Basic Information
Gene ID 100995808
Gene Name MLL2
Full Name PREDICTED: histone-lysine N-methyltransferase MLL2 [Pan paniscus].
Organism Pan paniscus [9597]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_003846168 Gene3D G3DSA:3.30.40.10 IPR013083 1208 1259 6.00e-08 Zinc finger, RING/FYVE/PHD-type
XP_003846168 Gene3D G3DSA:3.30.40.10 IPR013083 1260 1307 3.20e-14 Zinc finger, RING/FYVE/PHD-type
XP_003846168 Gene3D G3DSA:3.30.40.10 IPR013083 1337 1390 7.30e-08 Zinc finger, RING/FYVE/PHD-type
XP_003846168 Gene3D G3DSA:3.30.40.10 IPR013083 216 274 2.70e-08 Zinc finger, RING/FYVE/PHD-type
XP_003846168 Gene3D G3DSA:3.30.40.10 IPR013083 275 321 2.90e-13 Zinc finger, RING/FYVE/PHD-type
XP_003846168 Pfam PF00628 IPR019787 1211 1260 2.80e-07 Zinc finger, PHD-finger
XP_003846168 Pfam PF00628 IPR019787 1261 1308 3.10e-09 Zinc finger, PHD-finger
XP_003846168 Pfam PF00628 IPR019787 275 322 3.80e-09 Zinc finger, PHD-finger
XP_003846168 Pfam PF00856 IPR001214 5244 5349 3.10e-24 SET domain
XP_003846168 Pfam PF05964 IPR003888 5016 5068 1.00e-20 FY-rich, N-terminal
XP_003846168 Pfam PF05965 IPR003889 5073 5159 3.50e-25 FY-rich, C-terminal
XP_003846168 ProSiteProfiles PS50016 IPR019787 1209 1262 0.00e-00 Zinc finger, PHD-finger
XP_003846168 ProSiteProfiles PS50016 IPR019787 1259 1309 0.00e-00 Zinc finger, PHD-finger
XP_003846168 ProSiteProfiles PS50016 IPR019787 1336 1391 0.00e-00 Zinc finger, PHD-finger
XP_003846168 ProSiteProfiles PS50016 IPR019787 226 276 0.00e-00 Zinc finger, PHD-finger
XP_003846168 ProSiteProfiles PS50016 IPR019787 273 323 0.00e-00 Zinc finger, PHD-finger
XP_003846168 ProSiteProfiles PS50089 IPR001841 229 274 0.00e-00 Zinc finger, RING-type
XP_003846168 ProSiteProfiles PS50280 IPR001214 5233 5349 0.00e-00 SET domain
XP_003846168 ProSiteProfiles PS50868 IPR003616 5357 5373 0.00e-00 Post-SET domain
XP_003846168 ProSiteProfiles PS51542 IPR003888 5011 5071 0.00e-00 FY-rich, N-terminal
XP_003846168 ProSiteProfiles PS51543 IPR003889 5072 5157 0.00e-00 FY-rich, C-terminal
XP_003846168 SMART SM00184 IPR001841 1212 1259 5.60e-02 Zinc finger, RING-type
XP_003846168 SMART SM00184 IPR001841 1339 1388 4.10e-02 Zinc finger, RING-type
XP_003846168 SMART SM00184 IPR001841 172 217 2.20e-02 Zinc finger, RING-type
XP_003846168 SMART SM00184 IPR001841 229 273 2.00e-05 Zinc finger, RING-type
XP_003846168 SMART SM00184 IPR001841 276 320 1.00e-02 Zinc finger, RING-type
XP_003846168 SMART SM00184 IPR001841 4928 4972 1.90e-02 Zinc finger, RING-type
XP_003846168 SMART SM00249 IPR001965 1211 1260 3.50e-11 Zinc finger, PHD-type
XP_003846168 SMART SM00249 IPR001965 1261 1307 4.30e-15 Zinc finger, PHD-type
XP_003846168 SMART SM00249 IPR001965 1338 1389 5.60e-09 Zinc finger, PHD-type
XP_003846168 SMART SM00249 IPR001965 171 218 8.70e-08 Zinc finger, PHD-type
XP_003846168 SMART SM00249 IPR001965 228 274 9.90e-10 Zinc finger, PHD-type
XP_003846168 SMART SM00249 IPR001965 275 321 3.80e-14 Zinc finger, PHD-type
XP_003846168 SMART SM00249 IPR001965 4927 4973 1.90e-07 Zinc finger, PHD-type
XP_003846168 SMART SM00317 IPR001214 5233 5355 2.80e-38 SET domain
XP_003846168 SMART SM00398 IPR009071 1844 1912 9.90e-09 High mobility group box domain
XP_003846168 SMART SM00508 IPR003616 5357 5373 1.40e-07 Post-SET domain
XP_003846168 SMART SM00541 IPR003888 5027 5070 2.10e-23 FY-rich, N-terminal
XP_003846168 SMART SM00542 IPR003889 5076 5163 8.60e-46 FY-rich, C-terminal
XP_003846168 SUPERFAMILY SSF47095 IPR009071 1854 1904 0.00e-00 High mobility group box domain
XP_003846168 SUPERFAMILY SSF57903 IPR011011 1206 1260 0.00e-00 Zinc finger, FYVE/PHD-type
XP_003846168 SUPERFAMILY SSF57903 IPR011011 1252 1312 0.00e-00 Zinc finger, FYVE/PHD-type
XP_003846168 SUPERFAMILY SSF57903 IPR011011 1327 1396 0.00e-00 Zinc finger, FYVE/PHD-type
XP_003846168 SUPERFAMILY SSF57903 IPR011011 224 277 0.00e-00 Zinc finger, FYVE/PHD-type
XP_003846168 SUPERFAMILY SSF57903 IPR011011 272 326 0.00e-00 Zinc finger, FYVE/PHD-type

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_003846168 PF00628 2.3e-34 PHD PHD-finger
XP_003846168 PF05965 8.9e-26 FYRC F/Y rich C-terminus
XP_003846168 PF00856 3.1e-24 SET SET domain
XP_003846168 PF13771 8e-23 zf-HC5HC2H PHD-like zinc-binding domain
XP_003846168 PF05964 5.7e-21 FYRN F/Y-rich N-terminus
XP_003846168 PF13832 5.4e-11 zf-HC5HC2H_2 PHD-zinc-finger like domain
XP_003846168 PF00505 0.00037 HMG_box HMG (high mobility group) box

Gene Ontology Annotation
Protein Entry Name Space Description
XP_003846168 GO:0051568 biological_process histone H3-K4 methylation
XP_003846168 GO:0005634 cellular_component nucleus
XP_003846168 GO:0035097 cellular_component histone methyltransferase complex
XP_003846168 GO:0008270 molecular_function zinc ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9555 Papio anubis 101013975 39432 Saimiri boliviensis 101037539
9615 Canis familiaris 486558 9606 Homo sapiens 8085
9646 Ailuropoda melanoleuca ENSAMEG00000006918 9913 Bos taurus ENSBTAG00000014429
9483 Callithrix jacchus ENSCJAG00000020845 10141 Cavia porcellus ENSCPOG00000002973
10020 Dipodomys ordii ENSDORG00000006509 9595 Gorilla gorilla ENSGGOG00000007949
9785 Loxodonta africana ENSLAFG00000009989 30608 Microcebus murinus ENSMICG00000017547
59463 Myotis lucifugus ENSMLUG00000011179 10090 Mus musculus ENSMUSG00000048154
61853 Nomascus leucogenys ENSNLEG00000017849 9986 Oryctolagus cuniculus ENSOCUG00000006202
30611 Otolemur garnettii ENSOGAG00000013443 9978 Ochotona princeps ENSOPRG00000015259
9813 Procavia capensis ENSPCAG00000003597 9601 Pongo abelii ENSPPYG00000004478
10116 Rattus norvegicus ENSRNOG00000015107 42254 Sorex araneus ENSSARG00000010487
43179 Ictidomys tridecemlineatus ENSSTOG00000003904 9739 Tursiops truncatus ENSTTRG00000004737
8364 Xenopus tropicalis ENSXETG00000011176 9365 Erinaceus europaeus ENSEEUG00000007930
9371 Echinops telfairi ENSETEG00000001399 9031 Gallus gallus ENSGALG00000025902
9544 Macaca mulatta ENSMMUG00000015718 9598 Pan troglodytes ENSPTRG00000004896
9823 Sus scrofa ENSSSCG00000000191 37347 Tupaia belangeri ENSTBEG00000001207