Basic Information
Gene ID 101043581
Gene Name NR3C1; GRL
Full Name Glucocorticoid receptor
Organism Saimiri boliviensis [39432]

Cross Reference
UniProt O13186 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_003920603 Gene3D G3DSA:1.10.565.10 IPR008946 535 762 7.20e-67 Nuclear hormone receptor, ligand-binding
XP_003920603 Gene3D G3DSA:3.30.50.10 IPR013088 418 497 3.00e-28 Zinc finger, NHR/GATA-type
XP_003920603 Pfam PF00104 IPR000536 544 735 4.90e-31 Nuclear hormone receptor, ligand-binding, core
XP_003920603 Pfam PF00105 IPR001628 420 487 4.40e-28 Zinc finger, nuclear hormone receptor-type
XP_003920603 Pfam PF02155 IPR001409 26 401 3.20e-179 Glucocorticoid receptor
XP_003920603 PRINTS PR00047 IPR001628 421 437 8.00e-14 Zinc finger, nuclear hormone receptor-type
XP_003920603 PRINTS PR00047 IPR001628 437 452 8.00e-14 Zinc finger, nuclear hormone receptor-type
XP_003920603 PRINTS PR00047 IPR001628 470 478 8.00e-14 Zinc finger, nuclear hormone receptor-type
XP_003920603 PRINTS PR00047 IPR001628 478 486 8.00e-14 Zinc finger, nuclear hormone receptor-type
XP_003920603 PRINTS PR00398 IPR001723 482 492 7.80e-13 Steroid hormone receptor
XP_003920603 PRINTS PR00398 IPR001723 566 587 7.80e-13 Steroid hormone receptor
XP_003920603 PRINTS PR00398 IPR001723 587 603 7.80e-13 Steroid hormone receptor
XP_003920603 PRINTS PR00398 IPR001723 656 671 7.80e-13 Steroid hormone receptor
XP_003920603 PRINTS PR00528 IPR001409 109 129 9.60e-77 Glucocorticoid receptor
XP_003920603 PRINTS PR00528 IPR001409 26 46 9.60e-77 Glucocorticoid receptor
XP_003920603 PRINTS PR00528 IPR001409 275 296 9.60e-77 Glucocorticoid receptor
XP_003920603 PRINTS PR00528 IPR001409 322 340 9.60e-77 Glucocorticoid receptor
XP_003920603 PRINTS PR00528 IPR001409 382 401 9.60e-77 Glucocorticoid receptor
XP_003920603 PRINTS PR00528 IPR001409 76 96 9.60e-77 Glucocorticoid receptor
XP_003920603 ProSitePatterns PS00031 IPR001628 421 447 - Zinc finger, nuclear hormone receptor-type
XP_003920603 ProSiteProfiles PS51030 IPR001628 418 493 0.00e-00 Zinc finger, nuclear hormone receptor-type
XP_003920603 SMART SM00399 IPR001628 418 489 2.50e-38 Zinc finger, nuclear hormone receptor-type
XP_003920603 SMART SM00430 IPR000536 565 729 6.70e-35 Nuclear hormone receptor, ligand-binding, core
XP_003920603 SUPERFAMILY SSF48508 IPR008946 530 776 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_003920603 PF02155 0 GCR Glucocorticoid receptor
XP_003920603 PF00104 3.1e-31 Hormone_recep Ligand-binding domain of nuclear hormone receptor
XP_003920603 PF00105 2.3e-28 zf-C4 Zinc finger, C4 type (two domains)

Gene Ontology Annotation
Protein Entry Name Space Description
XP_003920603 GO:0006351 biological_process transcription, DNA-templated
XP_003920603 GO:0006355 biological_process regulation of transcription, DNA-templated
XP_003920603 GO:0016568 biological_process chromatin modification
XP_003920603 GO:0042921 biological_process glucocorticoid receptor signaling pathway
XP_003920603 GO:0043401 biological_process steroid hormone mediated signaling pathway
XP_003920603 GO:0043402 biological_process glucocorticoid mediated signaling pathway
XP_003920603 GO:0005634 cellular_component nucleus
XP_003920603 GO:0005737 cellular_component cytoplasm
XP_003920603 GO:0005739 cellular_component mitochondrion
XP_003920603 GO:0003677 molecular_function DNA binding
XP_003920603 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
XP_003920603 GO:0003707 molecular_function steroid hormone receptor activity
XP_003920603 GO:0004883 molecular_function glucocorticoid receptor activity
XP_003920603 GO:0005496 molecular_function steroid binding
XP_003920603 GO:0008270 molecular_function zinc ion binding
XP_003920603 GO:0008289 molecular_function lipid binding
XP_003920603 GO:0043565 molecular_function sequence-specific DNA binding
XP_003920603 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9601 Pongo abelii 100189725 8128 Oreochromis niloticus 100534398
9597 Pan paniscus 100970978 9555 Papio anubis 101011541
59729 Taeniopygia guttata 100008583 9796 Equus caballus 100061217
9483 Callithrix jacchus 100394916 61853 Nomascus leucogenys 100605325
9785 Loxodonta africana 100664515 10029 Cricetulus griseus 100763961
31033 Takifugu rubripes 101062852 9669 Mustela putorius furo 101688907
7897 Latimeria chalumnae 102354325 13735 Pelodiscus sinensis 102454070
10090 Mus musculus 14815 9606 Homo sapiens 2908
9823 Sus scrofa 396740 9615 Canis familiaris 478047
9646 Ailuropoda melanoleuca ENSAMEG00000010159 9358 Choloepus hoffmanni ENSCHOG00000013777
10020 Dipodomys ordii ENSDORG00000010001 9365 Erinaceus europaeus ENSEEUG00000008977
9371 Echinops telfairi ENSETEG00000014280 9685 Felis catus ENSFCAG00000026823
8049 Gadus morhua ENSGMOG00000005668 9103 Meleagris gallopavo ENSMGAG00000009322
9544 Macaca mulatta ENSMMUG00000000421 9258 Ornithorhynchus anatinus ENSOANG00000005745
9986 Oryctolagus cuniculus ENSOCUG00000011676 30611 Otolemur garnettii ENSOGAG00000003356
9978 Ochotona princeps ENSOPRG00000015535 8090 Oryzias latipes ENSORLG00000006022
9598 Pan troglodytes ENSPTRG00000017363 132908 Pteropus vampyrus ENSPVAG00000014255
10116 Rattus norvegicus ENSRNOG00000014096 9305 Sarcophilus harrisii ENSSHAG00000001727
37347 Tupaia belangeri ENSTBEG00000016278 99883 Tetraodon nigroviridis ENSTNIG00000008946
9739 Tursiops truncatus ENSTTRG00000003260 30538 Vicugna pacos ENSVPAG00000006590
8364 Xenopus tropicalis ENSXETG00000001879 8083 Xiphophorus maculatus ENSXMAG00000009167
43179 Ictidomys tridecemlineatus 101954529 59463 Myotis lucifugus 102429264
9361 Dasypus novemcinctus ENSDNOG00000010685 69293 Gasterosteus aculeatus ENSGACG00000018209
9031 Gallus gallus ENSGALG00000007394 9595 Gorilla gorilla ENSGGOG00000004334
9315 Macropus eugenii ENSMEUG00000009869 30608 Microcebus murinus ENSMICG00000009473
42254 Sorex araneus ENSSARG00000000617 9478 Tarsius syrichta ENSTSYG00000013696