Basic Information | |||
Gene ID | 101089873 | ||
Gene Name | STAT6 | ||
Full Name | Signal transducer and activator of transcription | ||
Organism | Felis catus [9685] |
Cross Reference | |||
UniProt | M3WKY3 | UniGene | NULL |
PDB | NULL | OMIM | NULL |
KEGG | fca:101089873 | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSFCAP00000013518 | Gene3D | G3DSA:1.10.238.10 | IPR011992 | 416 | 541 | 2.40e-41 | EF-hand domain pair |
ENSFCAP00000013518 | Gene3D | G3DSA:1.10.532.10 | IPR013799 | 1 | 113 | 6.40e-23 | STAT transcription factor, protein interaction |
ENSFCAP00000013518 | Gene3D | G3DSA:1.20.1050.20 | IPR013800 | 114 | 273 | 2.20e-25 | STAT transcription factor, all-alpha |
ENSFCAP00000013518 | Gene3D | G3DSA:2.60.40.630 | IPR012345 | 275 | 415 | 2.10e-44 | STAT transcription factor, DNA-binding, subdomain |
ENSFCAP00000013518 | Gene3D | G3DSA:3.30.505.10 | IPR000980 | 542 | 650 | 6.70e-37 | SH2 domain |
ENSFCAP00000013518 | PANTHER | PTHR11801 | IPR001217 | 2 | 718 | 0.00e-00 | Transcription factor STAT |
ENSFCAP00000013518 | Pfam | PF00017 | IPR000980 | 538 | 616 | 3.60e-10 | SH2 domain |
ENSFCAP00000013518 | Pfam | PF01017 | IPR013800 | 124 | 271 | 8.10e-24 | STAT transcription factor, all-alpha |
ENSFCAP00000013518 | Pfam | PF02864 | IPR013801 | 273 | 527 | 5.80e-94 | STAT transcription factor, DNA-binding |
ENSFCAP00000013518 | Pfam | PF02865 | IPR013799 | 2 | 115 | 8.70e-23 | STAT transcription factor, protein interaction |
ENSFCAP00000013518 | Pfam | PF14596 | IPR028187 | 655 | 844 | 1.20e-100 | STAT6, C-terminal |
ENSFCAP00000013518 | ProSiteProfiles | PS50001 | IPR000980 | 517 | 632 | 0.00e-00 | SH2 domain |
ENSFCAP00000013518 | SMART | SM00252 | IPR000980 | 540 | 622 | 1.60e-07 | SH2 domain |
ENSFCAP00000013518 | SMART | SM00964 | IPR013799 | 2 | 116 | 5.10e-36 | STAT transcription factor, protein interaction |
ENSFCAP00000013518 | SUPERFAMILY | SSF47655 | IPR015988 | 112 | 273 | 0.00e-00 | STAT transcription factor, coiled coil |
ENSFCAP00000013518 | SUPERFAMILY | SSF48092 | IPR013799 | 1 | 115 | 0.00e-00 | STAT transcription factor, protein interaction |
ENSFCAP00000013518 | SUPERFAMILY | SSF49417 | IPR008967 | 265 | 528 | 0.00e-00 | p53-like transcription factor, DNA-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSFCAP00000013518 | PF02864 | 0 | STAT_bind | STAT protein, DNA binding domain |
ENSFCAP00000013518 | PF14596 | 0 | STAT6_C | STAT6 C-terminal |
ENSFCAP00000013518 | PF01017 | 3.2e-25 | STAT_alpha | STAT protein, all-alpha domain |
ENSFCAP00000013518 | PF02865 | 2.4e-23 | STAT_int | STAT protein, protein interaction domain |
ENSFCAP00000013518 | PF00017 | 1.5e-10 | SH2 | SH2 domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSFCAP00000013518 | GO:0001553 | biological_process | luteinization |
ENSFCAP00000013518 | GO:0001779 | biological_process | natural killer cell differentiation |
ENSFCAP00000013518 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSFCAP00000013518 | GO:0007259 | biological_process | JAK-STAT cascade |
ENSFCAP00000013518 | GO:0007565 | biological_process | female pregnancy |
ENSFCAP00000013518 | GO:0007595 | biological_process | lactation |
ENSFCAP00000013518 | GO:0019218 | biological_process | regulation of steroid metabolic process |
ENSFCAP00000013518 | GO:0019915 | biological_process | lipid storage |
ENSFCAP00000013518 | GO:0030155 | biological_process | regulation of cell adhesion |
ENSFCAP00000013518 | GO:0030856 | biological_process | regulation of epithelial cell differentiation |
ENSFCAP00000013518 | GO:0038161 | biological_process | prolactin signaling pathway |
ENSFCAP00000013518 | GO:0040018 | biological_process | positive regulation of multicellular organism growth |
ENSFCAP00000013518 | GO:0042104 | biological_process | positive regulation of activated T cell proliferation |
ENSFCAP00000013518 | GO:0043029 | biological_process | T cell homeostasis |
ENSFCAP00000013518 | GO:0045086 | biological_process | positive regulation of interleukin-2 biosynthetic process |
ENSFCAP00000013518 | GO:0045579 | biological_process | positive regulation of B cell differentiation |
ENSFCAP00000013518 | GO:0045647 | biological_process | negative regulation of erythrocyte differentiation |
ENSFCAP00000013518 | GO:0045931 | biological_process | positive regulation of mitotic cell cycle |
ENSFCAP00000013518 | GO:0045944 | biological_process | positive regulation of transcription from RNA polymerase II promoter |
ENSFCAP00000013518 | GO:0046543 | biological_process | development of secondary female sexual characteristics |
ENSFCAP00000013518 | GO:0050729 | biological_process | positive regulation of inflammatory response |
ENSFCAP00000013518 | GO:0005634 | cellular_component | nucleus |
ENSFCAP00000013518 | GO:0005737 | cellular_component | cytoplasm |
ENSFCAP00000013518 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSFCAP00000013518 | GO:0004871 | molecular_function | signal transducer activity |
ENSFCAP00000013518 | GO:0005509 | molecular_function | calcium ion binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
9796 | Equus caballus | 100050053 | 9823 | Sus scrofa | 100627682 |
10029 | Cricetulus griseus | 100753838 | 30611 | Otolemur garnettii | 100949888 |
9597 | Pan paniscus | 100989067 | 9555 | Papio anubis | 101023204 |
39432 | Saimiri boliviensis | 101029869 | 31033 | Takifugu rubripes | 101065277 |
9595 | Gorilla gorilla | 101130575 | 9669 | Mustela putorius furo | 101676980 |
43179 | Ictidomys tridecemlineatus | 101967693 | 9544 | Macaca mulatta | 714159 |
28377 | Anolis carolinensis | ENSACAG00000009680 | 9365 | Erinaceus europaeus | ENSEEUG00000005856 |
9371 | Echinops telfairi | ENSETEG00000014957 | 9315 | Macropus eugenii | ENSMEUG00000016670 |
59463 | Myotis lucifugus | ENSMLUG00000006689 | 13616 | Monodelphis domestica | ENSMODG00000019411 |
61853 | Nomascus leucogenys | ENSNLEG00000017396 | 9978 | Ochotona princeps | ENSOPRG00000013409 |
9813 | Procavia capensis | ENSPCAG00000009432 | 132908 | Pteropus vampyrus | ENSPVAG00000003949 |
42254 | Sorex araneus | ENSSARG00000001630 | 37347 | Tupaia belangeri | ENSTBEG00000013664 |
59729 | Taeniopygia guttata | ENSTGUG00000015716 | 9478 | Tarsius syrichta | ENSTSYG00000000267 |
9739 | Tursiops truncatus | ENSTTRG00000013064 | 8364 | Xenopus tropicalis | ENSXETG00000004431 |
9483 | Callithrix jacchus | ENSCJAG00000010327 | 10020 | Dipodomys ordii | ENSDORG00000012548 |
9785 | Loxodonta africana | ENSLAFG00000005970 | 30608 | Microcebus murinus | ENSMICG00000009087 |
9601 | Pongo abelii | ENSPPYG00000004680 | 9598 | Pan troglodytes | ENSPTRG00000005121 |