Basic Information
Gene ID 15376 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Foxa2; Hnf3b, Tcf-3b, Tcf3b
Full Name Hepatocyte nuclear factor 3-beta
Organism Mus musculus [10090]

Cross Reference
UniProt P35583 UniGene Mm.938
PDB NULL OMIM NULL
KEGG mmu:15376 UCSC uc008mta.1

Protein Interactions
DIP NULL
IntAct P35583
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000105590 Gene3D G3DSA:1.10.10.10 IPR011991 158 252 2.10e-41 Winged helix-turn-helix DNA-binding domain
ENSMUSP00000105590 Pfam PF00250 IPR001766 165 260 1.30e-46 Transcription factor, fork head
ENSMUSP00000105590 Pfam PF08430 IPR013638 23 164 2.50e-23 Fork-head N-terminal
ENSMUSP00000105590 Pfam PF09354 IPR018533 380 454 1.20e-22 Forkhead box protein, C-terminal
ENSMUSP00000105590 PRINTS PR00053 IPR001766 165 178 2.90e-24 Transcription factor, fork head
ENSMUSP00000105590 PRINTS PR00053 IPR001766 186 203 2.90e-24 Transcription factor, fork head
ENSMUSP00000105590 PRINTS PR00053 IPR001766 209 226 2.90e-24 Transcription factor, fork head
ENSMUSP00000105590 ProSitePatterns PS00657 IPR018122 165 178 - Transcription factor, fork head, conserved site
ENSMUSP00000105590 ProSitePatterns PS00658 IPR018122 209 215 - Transcription factor, fork head, conserved site
ENSMUSP00000105590 ProSiteProfiles PS50039 IPR001766 165 259 0.00e-00 Transcription factor, fork head
ENSMUSP00000105590 SMART SM00339 IPR001766 163 253 1.60e-64 Transcription factor, fork head

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000105590 PF00250 0 Fork_head Fork head domain
ENSMUSP00000105590 PF08430 2.5e-23 Fork_head_N Forkhead N-terminal region
ENSMUSP00000105590 PF09354 1.2e-22 HNF_C HNF3 C-terminal domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000105590 GO:0005634 cellular_component nucleus
ENSMUSP00000105590 GO:0003677 molecular_function DNA binding
ENSMUSP00000105590 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMUSP00000105590 GO:0008134 molecular_function transcription factor binding
ENSMUSP00000105590 GO:0019904 molecular_function protein domain specific binding
ENSMUSP00000105590 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9031 Gallus gallus 100859030 7425 Nasonia vitripennis 100123589
6087 Hydra magnipapillata 100202271 10224 Saccoglossus kowalevskii 100302707
9483 Callithrix jacchus 100389929 9646 Ailuropoda melanoleuca 100483366
9823 Sus scrofa 100513828 28377 Anolis carolinensis 100556026
7029 Acyrthosiphon pisum 100569272 30195 Bombus terrestris 100650207
8128 Oreochromis niloticus 100709336 132113 Bombus impatiens 100744463
7463 Apis florea 100864351 143995 Megachile rotundata 100876229
34638 Metaseiulus occidentalis 100906595 9597 Pan paniscus 100978881
9555 Papio anubis 101015279 39432 Saimiri boliviensis 101029549
9595 Gorilla gorilla 101142518 9669 Mustela putorius furo 101680872
43179 Ictidomys tridecemlineatus 101959361 8083 Xiphophorus maculatus 102235112
7897 Latimeria chalumnae 102350308 6239 Caenorhabditis elegans 173740
8364 Xenopus tropicalis 395063 7460 Apis mellifera 411296
7227 Drosophila melanogaster 43383 9606 Homo sapiens 442425
7668 Strongylocentrotus purpuratus 578584 7070 Tribolium castaneum 641542
9913 Bos taurus ENSBTAG00000012407 9358 Choloepus hoffmanni ENSCHOG00000007726
7719 Ciona intestinalis ENSCING00000023488 10141 Cavia porcellus ENSCPOG00000027068
51511 Ciona savignyi ENSCSAVG00000004649 9361 Dasypus novemcinctus ENSDNOG00000006385
9685 Felis catus ENSFCAG00000012368 8049 Gadus morhua ENSGMOG00000018910
9785 Loxodonta africana ENSLAFG00000026345 9315 Macropus eugenii ENSMEUG00000013519
13616 Monodelphis domestica ENSMODG00000006213 9258 Ornithorhynchus anatinus ENSOANG00000015108
9986 Oryctolagus cuniculus ENSOCUG00000007368 9978 Ochotona princeps ENSOPRG00000006139
8090 Oryzias latipes ENSORLG00000017407 9813 Procavia capensis ENSPCAG00000014796
7757 Petromyzon marinus ENSPMAG00000005222 132908 Pteropus vampyrus ENSPVAG00000015464
10116 Rattus norvegicus ENSRNOG00000013133 9305 Sarcophilus harrisii ENSSHAG00000014905
59729 Taeniopygia guttata ENSTGUG00000007523 99883 Tetraodon nigroviridis ENSTNIG00000016890
31033 Takifugu rubripes ENSTRUG00000008187 9478 Tarsius syrichta ENSTSYG00000005803
9796 Equus caballus ENSECAG00000026854 69293 Gasterosteus aculeatus ENSGACG00000006986