Basic Information
Gene ID 43383
Gene Name fkh; CG10002
Full Name Protein fork head
Organism Drosophila melanogaster [7227]

Cross Reference
UniProt P14734 UniGene Dm.22561
PDB NULL OMIM NULL
KEGG dme:Dmel_CG10002 UCSC NULL

Protein Interactions
DIP DIP-17045N
IntAct P14734
MINT MINT-307436
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
FBpp0289487 Gene3D G3DSA:1.10.10.10 IPR011991 203 297 1.00e-39 Winged helix-turn-helix DNA-binding domain
FBpp0289487 Pfam PF00250 IPR001766 210 305 8.70e-45 Transcription factor, fork head
FBpp0289487 Pfam PF08430 IPR013638 102 209 4.50e-22 Fork-head N-terminal
FBpp0289487 Pfam PF09354 IPR018533 449 486 5.10e-10 Forkhead box protein, C-terminal
FBpp0289487 PRINTS PR00053 IPR001766 210 223 5.30e-24 Transcription factor, fork head
FBpp0289487 PRINTS PR00053 IPR001766 231 248 5.30e-24 Transcription factor, fork head
FBpp0289487 PRINTS PR00053 IPR001766 254 271 5.30e-24 Transcription factor, fork head
FBpp0289487 ProSitePatterns PS00657 IPR018122 210 223 - Transcription factor, fork head, conserved site
FBpp0289487 ProSitePatterns PS00658 IPR018122 254 260 - Transcription factor, fork head, conserved site
FBpp0289487 ProSiteProfiles PS50039 IPR001766 210 304 0.00e-00 Transcription factor, fork head
FBpp0289487 SMART SM00339 IPR001766 208 298 6.50e-62 Transcription factor, fork head

Pfam Annotation
Protein Pfam ID E.value Name Description
FBpp0289487 PF00250 5.60519e-45 Fork_head Fork head domain
FBpp0289487 PF08430 1.2e-22 Fork_head_N Forkhead N-terminal region
FBpp0289487 PF09354 5.1e-10 HNF_C HNF3 C-terminal domain

Gene Ontology Annotation
Protein Entry Name Space Description
FBpp0289487 GO:0006351 biological_process transcription, DNA-templated
FBpp0289487 GO:0006355 biological_process regulation of transcription, DNA-templated
FBpp0289487 GO:0005634 cellular_component nucleus
FBpp0289487 GO:0003677 molecular_function DNA binding
FBpp0289487 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
FBpp0289487 GO:0008134 molecular_function transcription factor binding
FBpp0289487 GO:0019904 molecular_function protein domain specific binding
FBpp0289487 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10224 Saccoglossus kowalevskii 100302707 9646 Ailuropoda melanoleuca 100483366
7029 Acyrthosiphon pisum 100569272 30195 Bombus terrestris 100650207
9785 Loxodonta africana 100662656 8128 Oreochromis niloticus 100709336
143995 Megachile rotundata 100876229 39432 Saimiri boliviensis 101029549
9595 Gorilla gorilla 101142518 8083 Xiphophorus maculatus 102235112
10090 Mus musculus 15376 8364 Xenopus tropicalis 395063
7425 Nasonia vitripennis 100123589 9823 Sus scrofa 100513828
61853 Nomascus leucogenys 100579885 34638 Metaseiulus occidentalis 100906595
9597 Pan paniscus 100971902 9555 Papio anubis 101015279
9669 Mustela putorius furo 101680872 43179 Ictidomys tridecemlineatus 101959361
7897 Latimeria chalumnae 102350308 13735 Pelodiscus sinensis 102462414
7460 Apis mellifera 411296 7070 Tribolium castaneum 641542
9913 Bos taurus ENSBTAG00000012407 9615 Canis familiaris ENSCAFG00000013743
51511 Ciona savignyi ENSCSAVG00000011291 9371 Echinops telfairi ENSETEG00000011013
9685 Felis catus ENSFCAG00000012368 9315 Macropus eugenii ENSMEUG00000013519
9986 Oryctolagus cuniculus ENSOCUG00000007368 30611 Otolemur garnettii ENSOGAG00000031319
9813 Procavia capensis ENSPCAG00000005390 7757 Petromyzon marinus ENSPMAG00000005222
9601 Pongo abelii ENSPPYG00000005758 9598 Pan troglodytes ENSPTRG00000006285
132908 Pteropus vampyrus ENSPVAG00000015464 9305 Sarcophilus harrisii ENSSHAG00000014905
59729 Taeniopygia guttata ENSTGUG00000007523 9478 Tarsius syrichta ENSTSYG00000005803
9739 Tursiops truncatus ENSTTRG00000002855 7668 Strongylocentrotus purpuratus 578584
28377 Anolis carolinensis ENSACAG00000001256 7719 Ciona intestinalis ENSCING00000023488
10141 Cavia porcellus ENSCPOG00000027068 7955 Danio rerio ENSDARG00000019150
9361 Dasypus novemcinctus ENSDNOG00000006385 9796 Equus caballus ENSECAG00000005936
69293 Gasterosteus aculeatus ENSGACG00000006986 8049 Gadus morhua ENSGMOG00000018910
30608 Microcebus murinus ENSMICG00000003135 59463 Myotis lucifugus ENSMLUG00000029779
9544 Macaca mulatta ENSMMUG00000009653 13616 Monodelphis domestica ENSMODG00000006213
9258 Ornithorhynchus anatinus ENSOANG00000015108 9978 Ochotona princeps ENSOPRG00000006139
8090 Oryzias latipes ENSORLG00000017407 10116 Rattus norvegicus ENSRNOG00000013133
42254 Sorex araneus ENSSARG00000008208 99883 Tetraodon nigroviridis ENSTNIG00000016890
31033 Takifugu rubripes ENSTRUG00000006136 30538 Vicugna pacos ENSVPAG00000009933