Basic Information
Gene ID 172732
Gene Name mef-2; CELE_W10D5.1, W10D5.1
Full Name Protein MEF-2
Organism Caenorhabditis elegans [6239]

Cross Reference
UniProt Q9U325 UniGene Cel.32745
PDB NULL OMIM NULL
KEGG cel:CELE_W10D5.1 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
W10D5.1 Pfam PF00319 IPR002100 10 59 1.10e-22 Transcription factor, MADS-box
W10D5.1 PRINTS PR00404 IPR002100 23 38 1.40e-26 Transcription factor, MADS-box
W10D5.1 PRINTS PR00404 IPR002100 3 23 1.40e-26 Transcription factor, MADS-box
W10D5.1 PRINTS PR00404 IPR002100 38 59 1.40e-26 Transcription factor, MADS-box
W10D5.1 ProSitePatterns PS00350 IPR002100 3 57 - Transcription factor, MADS-box
W10D5.1 ProSiteProfiles PS50066 IPR002100 1 61 0.00e-00 Transcription factor, MADS-box
W10D5.1 SMART SM00432 IPR002100 1 60 4.30e-40 Transcription factor, MADS-box
W10D5.1 SUPERFAMILY SSF55455 IPR002100 2 90 0.00e-00 Transcription factor, MADS-box

Pfam Annotation
Protein Pfam ID E.value Name Description
W10D5.1 PF00319 6e-23 SRF-TF SRF-type transcription factor (DNA-binding and dimerisation domain)

Gene Ontology Annotation
Protein Entry Name Space Description
W10D5.1 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
W10D5.1 GO:0000165 biological_process MAPK cascade
W10D5.1 GO:0006366 biological_process transcription from RNA polymerase II promoter
W10D5.1 GO:0006915 biological_process apoptotic process
W10D5.1 GO:0007507 biological_process heart development
W10D5.1 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
W10D5.1 GO:0071277 biological_process cellular response to calcium ion
W10D5.1 GO:0005634 cellular_component nucleus
W10D5.1 GO:0005737 cellular_component cytoplasm
W10D5.1 GO:0000977 molecular_function RNA polymerase II regulatory region sequence-specific DNA binding
W10D5.1 GO:0000981 molecular_function sequence-specific DNA binding RNA polymerase II transcription factor activity
W10D5.1 GO:0001077 molecular_function RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
W10D5.1 GO:0003677 molecular_function DNA binding
W10D5.1 GO:0003682 molecular_function chromatin binding
W10D5.1 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
W10D5.1 GO:0033613 molecular_function activating transcription factor binding
W10D5.1 GO:0042826 molecular_function histone deacetylase binding
W10D5.1 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10224 Saccoglossus kowalevskii 100313657 9646 Ailuropoda melanoleuca 100464632
9685 Felis catus 101098464 7425 Nasonia vitripennis 100122265
6087 Hydra magnipapillata 100204453 7029 Acyrthosiphon pisum 100572713
400682 Amphimedon queenslandica 100636842 30195 Bombus terrestris 100649884
10141 Cavia porcellus 100725079 132113 Bombus impatiens 100745731
10029 Cricetulus griseus 100754401 7463 Apis florea 100871942
143995 Megachile rotundata 100877544 34638 Metaseiulus occidentalis 100902919
9597 Pan paniscus 100989820 9555 Papio anubis 101002825
39432 Saimiri boliviensis 101029713 31033 Takifugu rubripes 101069405
9669 Mustela putorius furo 101686957 7897 Latimeria chalumnae 102348604
10090 Mus musculus 17258 7227 Drosophila melanogaster 36032
7460 Apis mellifera 413946 9606 Homo sapiens 4205
9598 Pan troglodytes 461760 7668 Strongylocentrotus purpuratus 591326
7070 Tribolium castaneum 660448 28377 Anolis carolinensis ENSACAG00000000488
9913 Bos taurus ENSBTAG00000020701 9483 Callithrix jacchus ENSCJAG00000005848
51511 Ciona savignyi ENSCSAVG00000003571 7955 Danio rerio ENSDARG00000057527
9361 Dasypus novemcinctus ENSDNOG00000018848 10020 Dipodomys ordii ENSDORG00000011003
9796 Equus caballus ENSECAG00000024716 9365 Erinaceus europaeus ENSEEUG00000007138
69293 Gasterosteus aculeatus ENSGACG00000013094 9031 Gallus gallus ENSGALG00000014645
9595 Gorilla gorilla ENSGGOG00000013064 8049 Gadus morhua ENSGMOG00000007476
9785 Loxodonta africana ENSLAFG00000004656 9103 Meleagris gallopavo ENSMGAG00000004354
30608 Microcebus murinus ENSMICG00000008255 59463 Myotis lucifugus ENSMLUG00000016420
9544 Macaca mulatta ENSMMUG00000019836 13616 Monodelphis domestica ENSMODG00000020223
61853 Nomascus leucogenys ENSNLEG00000012609 9258 Ornithorhynchus anatinus ENSOANG00000011076
9986 Oryctolagus cuniculus ENSOCUG00000012173 30611 Otolemur garnettii ENSOGAG00000008728
8128 Oreochromis niloticus ENSONIG00000015941 8090 Oryzias latipes ENSORLG00000010062
9813 Procavia capensis ENSPCAG00000001596 9601 Pongo abelii ENSPPYG00000015621
13735 Pelodiscus sinensis ENSPSIG00000012244 132908 Pteropus vampyrus ENSPVAG00000014423
42254 Sorex araneus ENSSARG00000005597 9305 Sarcophilus harrisii ENSSHAG00000016994
9823 Sus scrofa ENSSSCG00000014149 43179 Ictidomys tridecemlineatus ENSSTOG00000028856
59729 Taeniopygia guttata ENSTGUG00000000676 9478 Tarsius syrichta ENSTSYG00000003647
30538 Vicugna pacos ENSVPAG00000011436 8364 Xenopus tropicalis ENSXETG00000018788
8083 Xiphophorus maculatus ENSXMAG00000011869 9615 Canis familiaris ENSCAFG00000010775
9358 Choloepus hoffmanni ENSCHOG00000010767 7719 Ciona intestinalis ENSCING00000000628
9371 Echinops telfairi ENSETEG00000018987 9315 Macropus eugenii ENSMEUG00000010585
9978 Ochotona princeps ENSOPRG00000012052 10116 Rattus norvegicus ENSRNOG00000033134
37347 Tupaia belangeri ENSTBEG00000006794 99883 Tetraodon nigroviridis ENSTNIG00000019230
9739 Tursiops truncatus ENSTTRG00000015831