Basic Information
Gene ID ENSPPYG00000015621
Gene Name MEF2C
Full Name Myocyte-specific enhancer factor 2C
Organism Pongo abelii [9601]

Cross Reference
UniProt H2PG23 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPPYP00000017465 Pfam PF00319 IPR002100 10 59 3.60e-22 Transcription factor, MADS-box
ENSPPYP00000017465 Pfam PF12347 IPR022102 95 155 7.50e-13 Holliday junction regulator protein family C-terminal
ENSPPYP00000017465 PRINTS PR00404 IPR002100 23 38 1.00e-25 Transcription factor, MADS-box
ENSPPYP00000017465 PRINTS PR00404 IPR002100 3 23 1.00e-25 Transcription factor, MADS-box
ENSPPYP00000017465 PRINTS PR00404 IPR002100 38 59 1.00e-25 Transcription factor, MADS-box
ENSPPYP00000017465 ProSitePatterns PS00350 IPR002100 3 57 - Transcription factor, MADS-box
ENSPPYP00000017465 ProSiteProfiles PS50066 IPR002100 1 61 0.00e-00 Transcription factor, MADS-box
ENSPPYP00000017465 SMART SM00432 IPR002100 1 60 8.50e-40 Transcription factor, MADS-box
ENSPPYP00000017465 SUPERFAMILY SSF55455 IPR002100 2 89 0.00e-00 Transcription factor, MADS-box

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPPYP00000017465 PF00319 2.1e-22 SRF-TF SRF-type transcription factor (DNA-binding and dimerisation domain)
ENSPPYP00000017465 PF12347 2.9e-13 HJURP_C Holliday junction regulator protein family C-terminal repeat

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPPYP00000017465 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSPPYP00000017465 GO:0000165 biological_process MAPK cascade
ENSPPYP00000017465 GO:0006351 biological_process transcription, DNA-templated
ENSPPYP00000017465 GO:0006366 biological_process transcription from RNA polymerase II promoter
ENSPPYP00000017465 GO:0006915 biological_process apoptotic process
ENSPPYP00000017465 GO:0007507 biological_process heart development
ENSPPYP00000017465 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSPPYP00000017465 GO:0071277 biological_process cellular response to calcium ion
ENSPPYP00000017465 GO:0005634 cellular_component nucleus
ENSPPYP00000017465 GO:0005737 cellular_component cytoplasm
ENSPPYP00000017465 GO:0000977 molecular_function RNA polymerase II regulatory region sequence-specific DNA binding
ENSPPYP00000017465 GO:0000981 molecular_function sequence-specific DNA binding RNA polymerase II transcription factor activity
ENSPPYP00000017465 GO:0001077 molecular_function RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
ENSPPYP00000017465 GO:0003677 molecular_function DNA binding
ENSPPYP00000017465 GO:0003682 molecular_function chromatin binding
ENSPPYP00000017465 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSPPYP00000017465 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9646 Ailuropoda melanoleuca 100464632 132113 Bombus impatiens 100745731
9555 Papio anubis 101019513 39432 Saimiri boliviensis 101029713
9595 Gorilla gorilla 101139415 7897 Latimeria chalumnae 102361694
6239 Caenorhabditis elegans 172732 9598 Pan troglodytes 461760
9615 Canis familiaris 479155 9358 Choloepus hoffmanni ENSCHOG00000010767
9796 Equus caballus ENSECAG00000024716 9978 Ochotona princeps ENSOPRG00000012052
6087 Hydra magnipapillata 100204453 7029 Acyrthosiphon pisum 100572713
30195 Bombus terrestris 100649884 10141 Cavia porcellus 100725079
7463 Apis florea 100871942 143995 Megachile rotundata 100877544
9597 Pan paniscus 100975251 31033 Takifugu rubripes 101069405
9669 Mustela putorius furo 101686957 7460 Apis mellifera 413946
28377 Anolis carolinensis ENSACAG00000000488 9913 Bos taurus ENSBTAG00000020701
10020 Dipodomys ordii ENSDORG00000010183 9365 Erinaceus europaeus ENSEEUG00000002968
9371 Echinops telfairi ENSETEG00000015637 9685 Felis catus ENSFCAG00000011595
69293 Gasterosteus aculeatus ENSGACG00000010270 9031 Gallus gallus ENSGALG00000014645
8049 Gadus morhua ENSGMOG00000000565 9785 Loxodonta africana ENSLAFG00000013761
9315 Macropus eugenii ENSMEUG00000012604 30608 Microcebus murinus ENSMICG00000005703
59463 Myotis lucifugus ENSMLUG00000008230 9544 Macaca mulatta ENSMMUG00000019836
13616 Monodelphis domestica ENSMODG00000020223 9258 Ornithorhynchus anatinus ENSOANG00000011076
30611 Otolemur garnettii ENSOGAG00000028682 8128 Oreochromis niloticus ENSONIG00000015941
8090 Oryzias latipes ENSORLG00000010062 9813 Procavia capensis ENSPCAG00000012944
13735 Pelodiscus sinensis ENSPSIG00000012244 9305 Sarcophilus harrisii ENSSHAG00000010347
43179 Ictidomys tridecemlineatus ENSSTOG00000001883 9478 Tarsius syrichta ENSTSYG00000003647
9739 Tursiops truncatus ENSTTRG00000003944 30538 Vicugna pacos ENSVPAG00000009789
8083 Xiphophorus maculatus ENSXMAG00000019414 132908 Pteropus vampyrus ENSPVAG00000009412
10116 Rattus norvegicus ENSRNOG00000033134 42254 Sorex araneus ENSSARG00000012570
9823 Sus scrofa ENSSSCG00000014149 37347 Tupaia belangeri ENSTBEG00000006794
59729 Taeniopygia guttata ENSTGUG00000000676 99883 Tetraodon nigroviridis ENSTNIG00000015441