Basic Information
Gene ID 20472 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Six2
Full Name Homeobox protein SIX2
Organism Mus musculus [10090]

Cross Reference
UniProt Q62232 UniGene Mm.5039
PDB NULL OMIM NULL
KEGG mmu:20472 UCSC uc008duc.2

Protein Interactions
DIP NULL
IntAct Q62232
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000024947 Gene3D G3DSA:1.10.10.60 IPR009057 125 196 6.60e-24 Homeodomain-like
ENSMUSP00000024947 Pfam PF00046 IPR001356 130 180 2.40e-14 Homeobox domain
ENSMUSP00000024947 ProSitePatterns PS00027 IPR017970 157 180 - Homeobox, conserved site
ENSMUSP00000024947 ProSiteProfiles PS50071 IPR001356 122 182 0.00e-00 Homeobox domain
ENSMUSP00000024947 SMART SM00389 IPR001356 125 186 3.60e-20 Homeobox domain
ENSMUSP00000024947 SUPERFAMILY SSF46689 IPR009057 122 193 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000024947 PF00046 8.8e-15 Homeobox Homeobox domain
ENSMUSP00000024947 PF05920 3e-12 Homeobox_KN Homeobox KN domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000024947 GO:0005634 cellular_component nucleus
ENSMUSP00000024947 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMUSP00000024947 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100115806 7029 Acyrthosiphon pisum 100160072
6087 Hydra magnipapillata 100192245 59729 Taeniopygia guttata 100218142
10224 Saccoglossus kowalevskii 100369568 9483 Callithrix jacchus 100397818
9646 Ailuropoda melanoleuca 100468465 61853 Nomascus leucogenys 100605305
30195 Bombus terrestris 100649208 132113 Bombus impatiens 100746030
10029 Cricetulus griseus 100767057 7463 Apis florea 100867252
143995 Megachile rotundata 100880596 34638 Metaseiulus occidentalis 100900652
9597 Pan paniscus 100973560 9555 Papio anubis 101018624
39432 Saimiri boliviensis 101054481 31033 Takifugu rubripes 101078813
9595 Gorilla gorilla 101131409 8090 Oryzias latipes 101161260
13735 Pelodiscus sinensis 102452073 9606 Homo sapiens 10736
6239 Caenorhabditis elegans 191622 400682 Amphimedon queenslandica 100639860
9305 Sarcophilus harrisii 100921913 9669 Mustela putorius furo 101676499
43179 Ictidomys tridecemlineatus 101976995 7897 Latimeria chalumnae 102365580
9358 Choloepus hoffmanni ENSCHOG00000001094 9365 Erinaceus europaeus ENSEEUG00000013612
9371 Echinops telfairi ENSETEG00000019169 69293 Gasterosteus aculeatus ENSGACG00000010790
9031 Gallus gallus ENSGALG00000023303 9315 Macropus eugenii ENSMEUG00000010820
9986 Oryctolagus cuniculus ENSOCUG00000027205 132908 Pteropus vampyrus ENSPVAG00000013457
9823 Sus scrofa ENSSSCG00000008446 7227 Drosophila melanogaster 35662
9598 Pan troglodytes 459197 9615 Canis familiaris 481357
7668 Strongylocentrotus purpuratus 576117 7070 Tribolium castaneum 660875
7955 Danio rerio 83415 28377 Anolis carolinensis ENSACAG00000023286
9913 Bos taurus ENSBTAG00000012139 7719 Ciona intestinalis ENSCING00000022188
51511 Ciona savignyi ENSCSAVG00000002607 9361 Dasypus novemcinctus ENSDNOG00000018725
10020 Dipodomys ordii ENSDORG00000005524 9796 Equus caballus ENSECAG00000017789
9685 Felis catus ENSFCAG00000029823 8049 Gadus morhua ENSGMOG00000015501
9785 Loxodonta africana ENSLAFG00000013981 30608 Microcebus murinus ENSMICG00000004949
59463 Myotis lucifugus ENSMLUG00000002337 9544 Macaca mulatta ENSMMUG00000023752
13616 Monodelphis domestica ENSMODG00000008640 30611 Otolemur garnettii ENSOGAG00000034436
9978 Ochotona princeps ENSOPRG00000003825 9813 Procavia capensis ENSPCAG00000002941
7757 Petromyzon marinus ENSPMAG00000009968 10116 Rattus norvegicus ENSRNOG00000024511
42254 Sorex araneus ENSSARG00000013256 37347 Tupaia belangeri ENSTBEG00000007513
99883 Tetraodon nigroviridis ENSTNIG00000007465 9478 Tarsius syrichta ENSTSYG00000002547
9739 Tursiops truncatus ENSTTRG00000013829 8364 Xenopus tropicalis ENSXETG00000016943
8083 Xiphophorus maculatus ENSXMAG00000016855