Basic Information
Gene ID 2104 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name ESRRG; ERR3, ERRG2, KIAA0832, NR3B3
Full Name Estrogen-related receptor gamma
Organism Homo sapiens [9606]

Cross Reference
UniProt P62508 UniGene Hs.738938
PDB 2ZKC OMIM 602969
KEGG hsa:2104 UCSC uc001hkw.2

Protein Interactions
DIP NULL
IntAct P62508
MINT MINT-4824700
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000355904 Gene3D G3DSA:1.10.565.10 IPR008946 195 469 5.50e-80 Nuclear hormone receptor, ligand-binding
ENSP00000355904 Gene3D G3DSA:3.30.50.10 IPR013088 128 194 3.00e-30 Zinc finger, NHR/GATA-type
ENSP00000355904 Pfam PF00104 IPR000536 264 456 4.20e-36 Nuclear hormone receptor, ligand-binding, core
ENSP00000355904 Pfam PF00105 IPR001628 132 199 1.20e-30 Zinc finger, nuclear hormone receptor-type
ENSP00000355904 PIRSF PIRSF002527 IPR024178 12 470 2.90e-212 Oestrogen receptor/oestrogen-related receptor
ENSP00000355904 PIRSF PIRSF500939 IPR027289 28 470 2.00e-302 Oestrogen-related receptor
ENSP00000355904 PRINTS PR00047 IPR001628 133 149 2.10e-17 Zinc finger, nuclear hormone receptor-type
ENSP00000355904 PRINTS PR00047 IPR001628 149 164 2.10e-17 Zinc finger, nuclear hormone receptor-type
ENSP00000355904 PRINTS PR00047 IPR001628 182 190 2.10e-17 Zinc finger, nuclear hormone receptor-type
ENSP00000355904 PRINTS PR00047 IPR001628 190 198 2.10e-17 Zinc finger, nuclear hormone receptor-type
ENSP00000355904 PRINTS PR00398 IPR001723 194 204 4.00e-28 Steroid hormone receptor
ENSP00000355904 PRINTS PR00398 IPR001723 283 304 4.00e-28 Steroid hormone receptor
ENSP00000355904 PRINTS PR00398 IPR001723 304 320 4.00e-28 Steroid hormone receptor
ENSP00000355904 PRINTS PR00398 IPR001723 371 386 4.00e-28 Steroid hormone receptor
ENSP00000355904 PRINTS PR00398 IPR001723 428 445 4.00e-28 Steroid hormone receptor
ENSP00000355904 PRINTS PR01292 IPR003078 113 130 8.00e-05 Retinoic acid receptor
ENSP00000355904 PRINTS PR01292 IPR003078 204 217 8.00e-05 Retinoic acid receptor
ENSP00000355904 PRINTS PR01292 IPR003078 393 414 8.00e-05 Retinoic acid receptor
ENSP00000355904 PRINTS PR01292 IPR003078 437 452 8.00e-05 Retinoic acid receptor
ENSP00000355904 ProSitePatterns PS00031 IPR001628 133 159 - Zinc finger, nuclear hormone receptor-type
ENSP00000355904 ProSiteProfiles PS51030 IPR001628 130 205 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSP00000355904 SMART SM00399 IPR001628 130 201 1.30e-42 Zinc finger, nuclear hormone receptor-type
ENSP00000355904 SMART SM00430 IPR000536 282 440 5.30e-43 Nuclear hormone receptor, ligand-binding, core
ENSP00000355904 SUPERFAMILY SSF48508 IPR008946 180 214 0.00e-00 Nuclear hormone receptor, ligand-binding
ENSP00000355904 SUPERFAMILY SSF48508 IPR008946 243 469 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000355904 PF00104 2.9e-36 Hormone_recep Ligand-binding domain of nuclear hormone receptor
ENSP00000355904 PF00105 5.9e-31 zf-C4 Zinc finger, C4 type (two domains)

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9823 Sus scrofa 100622056 8364 Xenopus tropicalis 100101684
7425 Nasonia vitripennis 100120388 9986 Oryctolagus cuniculus 100355568
30195 Bombus terrestris 100644400 8128 Oreochromis niloticus 100704106
10141 Cavia porcellus 100719060 132113 Bombus impatiens 100747415
7463 Apis florea 100863304 143995 Megachile rotundata 100882199
34638 Metaseiulus occidentalis 100897394 9597 Pan paniscus 100987874
9555 Papio anubis 101012193 39432 Saimiri boliviensis 101046524
9595 Gorilla gorilla 101151743 7897 Latimeria chalumnae 102356802
13735 Pelodiscus sinensis 102450760 10090 Mus musculus 26380
10116 Rattus norvegicus 360896 7227 Drosophila melanogaster 38912
7955 Danio rerio 405890 7460 Apis mellifera 408855
9031 Gallus gallus 421357 9598 Pan troglodytes 453056
7070 Tribolium castaneum 654940 28377 Anolis carolinensis ENSACAG00000005586
9646 Ailuropoda melanoleuca ENSAMEG00000001292 9913 Bos taurus ENSBTAG00000010392
9615 Canis familiaris ENSCAFG00000017141 9358 Choloepus hoffmanni ENSCHOG00000008398
9483 Callithrix jacchus ENSCJAG00000020709 51511 Ciona savignyi ENSCSAVG00000002034
10020 Dipodomys ordii ENSDORG00000005752 9796 Equus caballus ENSECAG00000015997
9365 Erinaceus europaeus ENSEEUG00000010749 9371 Echinops telfairi ENSETEG00000012269
9685 Felis catus ENSFCAG00000028489 69293 Gasterosteus aculeatus ENSGACG00000016275
8049 Gadus morhua ENSGMOG00000003378 9785 Loxodonta africana ENSLAFG00000007032
9315 Macropus eugenii ENSMEUG00000000109 9103 Meleagris gallopavo ENSMGAG00000009436
30608 Microcebus murinus ENSMICG00000005051 59463 Myotis lucifugus ENSMLUG00000005021
9544 Macaca mulatta ENSMMUG00000014167 13616 Monodelphis domestica ENSMODG00000004163
9669 Mustela putorius furo ENSMPUG00000004285 61853 Nomascus leucogenys ENSNLEG00000014216
9258 Ornithorhynchus anatinus ENSOANG00000008544 30611 Otolemur garnettii ENSOGAG00000014802
9978 Ochotona princeps ENSOPRG00000013780 8090 Oryzias latipes ENSORLG00000011528
9813 Procavia capensis ENSPCAG00000005590 7757 Petromyzon marinus ENSPMAG00000002463
9601 Pongo abelii ENSPPYG00000000217 132908 Pteropus vampyrus ENSPVAG00000008613
42254 Sorex araneus ENSSARG00000013825 9305 Sarcophilus harrisii ENSSHAG00000010535
43179 Ictidomys tridecemlineatus ENSSTOG00000009493 37347 Tupaia belangeri ENSTBEG00000003245
59729 Taeniopygia guttata ENSTGUG00000002862 99883 Tetraodon nigroviridis ENSTNIG00000017413
31033 Takifugu rubripes ENSTRUG00000001481 9478 Tarsius syrichta ENSTSYG00000007446
9739 Tursiops truncatus ENSTTRG00000006004 30538 Vicugna pacos ENSVPAG00000005190
8083 Xiphophorus maculatus ENSXMAG00000014672 7719 Ciona intestinalis ENSCING00000018200