Basic Information
Gene ID 31165
Gene Name usp; Cf1, NR2B4; CG4380
Full Name Protein ultraspiracle
Organism Drosophila melanogaster [7227]

Cross Reference
UniProt P20153 UniGene Dm.25
PDB 2HAN OMIM NULL
KEGG dme:Dmel_CG4380 UCSC NULL

Protein Interactions
DIP DIP-645N
IntAct P20153
MINT MINT-824030
STRING 7227.FBpp0070332

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
FBpp0305937 Gene3D G3DSA:1.10.565.10 IPR008946 166 207 5.00e-75 Nuclear hormone receptor, ligand-binding
FBpp0305937 Gene3D G3DSA:1.10.565.10 IPR008946 257 498 5.00e-75 Nuclear hormone receptor, ligand-binding
FBpp0305937 Gene3D G3DSA:3.30.50.10 IPR013088 101 165 4.00e-32 Zinc finger, NHR/GATA-type
FBpp0305937 Pfam PF00104 IPR000536 278 480 3.40e-25 Nuclear hormone receptor, ligand-binding, core
FBpp0305937 Pfam PF00105 IPR001628 103 171 1.20e-30 Zinc finger, nuclear hormone receptor-type
FBpp0305937 PRINTS PR00047 IPR001628 104 120 1.70e-18 Zinc finger, nuclear hormone receptor-type
FBpp0305937 PRINTS PR00047 IPR001628 120 135 1.70e-18 Zinc finger, nuclear hormone receptor-type
FBpp0305937 PRINTS PR00047 IPR001628 153 161 1.70e-18 Zinc finger, nuclear hormone receptor-type
FBpp0305937 PRINTS PR00047 IPR001628 161 169 1.70e-18 Zinc finger, nuclear hormone receptor-type
FBpp0305937 PRINTS PR00398 IPR001723 165 175 4.10e-29 Steroid hormone receptor
FBpp0305937 PRINTS PR00398 IPR001723 284 305 4.10e-29 Steroid hormone receptor
FBpp0305937 PRINTS PR00398 IPR001723 305 321 4.10e-29 Steroid hormone receptor
FBpp0305937 PRINTS PR00398 IPR001723 400 415 4.10e-29 Steroid hormone receptor
FBpp0305937 PRINTS PR00398 IPR001723 457 474 4.10e-29 Steroid hormone receptor
FBpp0305937 PRINTS PR00545 IPR000003 172 185 1.50e-26 Retinoid X receptor/HNF4
FBpp0305937 PRINTS PR00545 IPR000003 362 387 1.50e-26 Retinoid X receptor/HNF4
FBpp0305937 PRINTS PR00545 IPR000003 388 406 1.50e-26 Retinoid X receptor/HNF4
FBpp0305937 PRINTS PR00545 IPR000003 429 448 1.50e-26 Retinoid X receptor/HNF4
FBpp0305937 ProSitePatterns PS00031 IPR001628 104 130 - Zinc finger, nuclear hormone receptor-type
FBpp0305937 ProSiteProfiles PS51030 IPR001628 101 176 0.00e-00 Zinc finger, nuclear hormone receptor-type
FBpp0305937 SMART SM00399 IPR001628 101 172 9.00e-40 Zinc finger, nuclear hormone receptor-type
FBpp0305937 SMART SM00430 IPR000536 283 469 3.90e-47 Nuclear hormone receptor, ligand-binding, core
FBpp0305937 SUPERFAMILY SSF48508 IPR008946 240 498 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
FBpp0305937 PF00105 4.3e-31 zf-C4 Zinc finger, C4 type (two domains)
FBpp0305937 PF00104 2e-25 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
FBpp0305937 GO:0006351 biological_process transcription, DNA-templated
FBpp0305937 GO:0006355 biological_process regulation of transcription, DNA-templated
FBpp0305937 GO:0043401 biological_process steroid hormone mediated signaling pathway
FBpp0305937 GO:0005634 cellular_component nucleus
FBpp0305937 GO:0003677 molecular_function DNA binding
FBpp0305937 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
FBpp0305937 GO:0003707 molecular_function steroid hormone receptor activity
FBpp0305937 GO:0008270 molecular_function zinc ion binding
FBpp0305937 GO:0043565 molecular_function sequence-specific DNA binding
FBpp0305937 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9796 Equus caballus 100069096 9258 Ornithorhynchus anatinus 100074625
7425 Nasonia vitripennis 100118473 7029 Acyrthosiphon pisum 100164958
61853 Nomascus leucogenys 100592610 30195 Bombus terrestris 100651492
132113 Bombus impatiens 100749223 143995 Megachile rotundata 100877684
34638 Metaseiulus occidentalis 100897482 9597 Pan paniscus 100989625
39432 Saimiri boliviensis 101044148 9669 Mustela putorius furo 101685997
13735 Pelodiscus sinensis 102443949 10090 Mus musculus 20181
10224 Saccoglossus kowalevskii 100329058 7463 Apis florea 100871050
9555 Papio anubis 101012079 9823 Sus scrofa 445465
10020 Dipodomys ordii ENSDORG00000009780 9595 Gorilla gorilla ENSGGOG00000009752
8049 Gadus morhua ENSGMOG00000014502 9601 Pongo abelii ENSPPYG00000019748
30538 Vicugna pacos ENSVPAG00000004578 7460 Apis mellifera 409227
9615 Canis familiaris 491278 7668 Strongylocentrotus purpuratus 579018
9606 Homo sapiens 6256 7070 Tribolium castaneum 661207
9544 Macaca mulatta 694807 10116 Rattus norvegicus 83574
28377 Anolis carolinensis ENSACAG00000007923 9646 Ailuropoda melanoleuca ENSAMEG00000006616
9913 Bos taurus ENSBTAG00000017851 9358 Choloepus hoffmanni ENSCHOG00000009952
9483 Callithrix jacchus ENSCJAG00000010148 10141 Cavia porcellus ENSCPOG00000000168
51511 Ciona savignyi ENSCSAVG00000007831 7955 Danio rerio ENSDARG00000035127
9361 Dasypus novemcinctus ENSDNOG00000015431 9365 Erinaceus europaeus ENSEEUG00000000887
9371 Echinops telfairi ENSETEG00000004886 9685 Felis catus ENSFCAG00000002431
69293 Gasterosteus aculeatus ENSGACG00000018189 9031 Gallus gallus ENSGALG00000002626
7897 Latimeria chalumnae ENSLACG00000006999 9785 Loxodonta africana ENSLAFG00000008059
9315 Macropus eugenii ENSMEUG00000013948 9103 Meleagris gallopavo ENSMGAG00000006819
30608 Microcebus murinus ENSMICG00000009970 59463 Myotis lucifugus ENSMLUG00000010476
13616 Monodelphis domestica ENSMODG00000013136 9986 Oryctolagus cuniculus ENSOCUG00000005512
30611 Otolemur garnettii ENSOGAG00000010970 8128 Oreochromis niloticus ENSONIG00000013076
9978 Ochotona princeps ENSOPRG00000000905 8090 Oryzias latipes ENSORLG00000012155
9813 Procavia capensis ENSPCAG00000008619 7757 Petromyzon marinus ENSPMAG00000007822
9598 Pan troglodytes ENSPTRG00000021527 132908 Pteropus vampyrus ENSPVAG00000001888
9305 Sarcophilus harrisii ENSSHAG00000015645 43179 Ictidomys tridecemlineatus ENSSTOG00000028427
37347 Tupaia belangeri ENSTBEG00000015312 59729 Taeniopygia guttata ENSTGUG00000005800
99883 Tetraodon nigroviridis ENSTNIG00000018446 31033 Takifugu rubripes ENSTRUG00000006349
9478 Tarsius syrichta ENSTSYG00000002120 9739 Tursiops truncatus ENSTTRG00000004291
8364 Xenopus tropicalis ENSXETG00000012733 8083 Xiphophorus maculatus ENSXMAG00000001735