Basic Information
Gene ID 3149 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name HMGB3; HMG2A, HMG4
Full Name High mobility group protein B3
Organism Homo sapiens [9606]

Cross Reference
UniProt O15347 UniGene Hs.19114
PDB 2YQI OMIM 300193
KEGG hsa:3149 UCSC uc004fep.3

Protein Interactions
DIP NULL
IntAct O15347
MINT MINT-5002211
STRING 9606.ENSP00000359393

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000472961 Gene3D G3DSA:1.10.30.10 IPR009071 8 78 1.30e-27 High mobility group box domain
ENSP00000472961 Gene3D G3DSA:1.10.30.10 IPR009071 91 165 7.50e-30 High mobility group box domain
ENSP00000472961 Pfam PF00505 IPR009071 93 161 1.60e-27 High mobility group box domain
ENSP00000472961 Pfam PF09011 IPR009071 6 78 4.70e-30 High mobility group box domain
ENSP00000472961 ProSitePatterns PS00353 IPR017967 41 52 - HMG box A DNA-binding domain, conserved site
ENSP00000472961 ProSiteProfiles PS50118 IPR009071 93 161 0.00e-00 High mobility group box domain
ENSP00000472961 ProSiteProfiles PS50118 IPR009071 9 79 0.00e-00 High mobility group box domain
ENSP00000472961 SMART SM00398 IPR009071 8 80 8.80e-28 High mobility group box domain
ENSP00000472961 SMART SM00398 IPR009071 92 162 2.80e-34 High mobility group box domain
ENSP00000472961 SUPERFAMILY SSF47095 IPR009071 3 79 0.00e-00 High mobility group box domain
ENSP00000472961 SUPERFAMILY SSF47095 IPR009071 81 162 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000472961 PF09011 0 HMG_box_2 HMG-box domain
ENSP00000472961 PF00505 5.10073e-43 HMG_box HMG (high mobility group) box
ENSP00000472961 PF14887 1.5e-06 HMG_box_5 HMG (high mobility group) box 5

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000472961 GO:0005634 cellular_component nucleus
ENSP00000472961 GO:0003677 molecular_function DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9823 Sus scrofa 100517745 10029 Cricetulus griseus 100772377
9597 Pan paniscus 100995089 9555 Papio anubis 101019418
39432 Saimiri boliviensis 101032929 9595 Gorilla gorilla 101129467
9669 Mustela putorius furo 101694047 43179 Ictidomys tridecemlineatus 101966850
7897 Latimeria chalumnae 102353521 59463 Myotis lucifugus 102434276
10090 Mus musculus 15354 10116 Rattus norvegicus 305373
9796 Equus caballus ENSECAG00000020596 9813 Procavia capensis ENSPCAG00000001945
8364 Xenopus tropicalis 448228 9615 Canis familiaris 481073
7955 Danio rerio 561025 9544 Macaca mulatta 703598
28377 Anolis carolinensis ENSACAG00000013274 9913 Bos taurus ENSBTAG00000031711
9358 Choloepus hoffmanni ENSCHOG00000005005 9483 Callithrix jacchus ENSCJAG00000033322
10141 Cavia porcellus ENSCPOG00000000601 10020 Dipodomys ordii ENSDORG00000010826
9371 Echinops telfairi ENSETEG00000015689 9685 Felis catus ENSFCAG00000024624
9031 Gallus gallus ENSGALG00000009071 30608 Microcebus murinus ENSMICG00000015668
13616 Monodelphis domestica ENSMODG00000005735 61853 Nomascus leucogenys ENSNLEG00000018249
9986 Oryctolagus cuniculus ENSOCUG00000005986 30611 Otolemur garnettii ENSOGAG00000001773
13735 Pelodiscus sinensis ENSPSIG00000015958 9598 Pan troglodytes ENSPTRG00000022371
132908 Pteropus vampyrus ENSPVAG00000000219 37347 Tupaia belangeri ENSTBEG00000003068
9478 Tarsius syrichta ENSTSYG00000014321 9739 Tursiops truncatus ENSTTRG00000000205
30538 Vicugna pacos ENSVPAG00000000096

Paralogs
3146