Basic Information
Gene ID 3146 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name HMGB1; HMG1
Full Name High mobility group protein B1
Organism Homo sapiens [9606]

Cross Reference
UniProt P09429 UniGene Hs.596078
PDB 2YRQ OMIM 163905
KEGG hsa:3146 UCSC uc001usx.3

Protein Interactions
DIP DIP-24195N
IntAct P09429
MINT MINT-153055
STRING 9606.ENSP00000343040

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000343040 Gene3D G3DSA:1.10.30.10 IPR009071 8 78 9.50e-30 High mobility group box domain
ENSP00000343040 Gene3D G3DSA:1.10.30.10 IPR009071 93 168 6.60e-32 High mobility group box domain
ENSP00000343040 Pfam PF00505 IPR009071 95 163 3.80e-27 High mobility group box domain
ENSP00000343040 Pfam PF09011 IPR009071 6 78 3.90e-27 High mobility group box domain
ENSP00000343040 ProSitePatterns PS00353 IPR017967 41 52 - HMG box A DNA-binding domain, conserved site
ENSP00000343040 ProSiteProfiles PS50118 IPR009071 95 163 0.00e-00 High mobility group box domain
ENSP00000343040 ProSiteProfiles PS50118 IPR009071 9 79 0.00e-00 High mobility group box domain
ENSP00000343040 SMART SM00398 IPR009071 8 80 2.80e-28 High mobility group box domain
ENSP00000343040 SMART SM00398 IPR009071 94 164 1.30e-32 High mobility group box domain
ENSP00000343040 SUPERFAMILY SSF47095 IPR009071 3 81 0.00e-00 High mobility group box domain
ENSP00000343040 SUPERFAMILY SSF47095 IPR009071 78 164 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000343040 PF09011 2.59941e-42 HMG_box_2 HMG-box domain
ENSP00000343040 PF00505 6.19934e-42 HMG_box HMG (high mobility group) box

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000343040 GO:0005634 cellular_component nucleus
ENSP00000343040 GO:0005694 cellular_component chromosome
ENSP00000343040 GO:0003677 molecular_function DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9796 Equus caballus 100033873 9555 Papio anubis 100137373
400682 Amphimedon queenslandica 100635010 10141 Cavia porcellus 100718808
31033 Takifugu rubripes 101074166 7227 Drosophila melanogaster 117294
7425 Nasonia vitripennis 100122354 7029 Acyrthosiphon pisum 100167132
6087 Hydra magnipapillata 100204109 9483 Callithrix jacchus 100392312
9601 Pongo abelii 100461759 9103 Meleagris gallopavo 100543659
61853 Nomascus leucogenys 100587901 132113 Bombus impatiens 100749348
7463 Apis florea 100871828 143995 Megachile rotundata 100876876
34638 Metaseiulus occidentalis 100900993 9597 Pan paniscus 100971286
39432 Saimiri boliviensis 101045330 9669 Mustela putorius furo 101675666
43179 Ictidomys tridecemlineatus 101976825 8083 Xiphophorus maculatus 102238067
7897 Latimeria chalumnae 102366474 59463 Myotis lucifugus 102420405
13735 Pelodiscus sinensis 102454149 10090 Mus musculus 15289
9913 Bos taurus 282691 7668 Strongylocentrotus purpuratus 373332
8364 Xenopus tropicalis 394834 9823 Sus scrofa 445521
7070 Tribolium castaneum 662763 9544 Macaca mulatta 712849
7460 Apis mellifera 725551 9598 Pan troglodytes 736904
7719 Ciona intestinalis 778643 28377 Anolis carolinensis ENSACAG00000005092
9646 Ailuropoda melanoleuca ENSAMEG00000011652 9615 Canis familiaris ENSCAFG00000023930
9358 Choloepus hoffmanni ENSCHOG00000002423 7955 Danio rerio ENSDARG00000029722
9361 Dasypus novemcinctus ENSDNOG00000012887 9365 Erinaceus europaeus ENSEEUG00000012238
9371 Echinops telfairi ENSETEG00000004048 9685 Felis catus ENSFCAG00000000200
69293 Gasterosteus aculeatus ENSGACG00000020545 9595 Gorilla gorilla ENSGGOG00000025109
8049 Gadus morhua ENSGMOG00000019231 9785 Loxodonta africana ENSLAFG00000030388
9315 Macropus eugenii ENSMEUG00000001380 30608 Microcebus murinus ENSMICG00000007144
13616 Monodelphis domestica ENSMODG00000008785 9258 Ornithorhynchus anatinus ENSOANG00000014719
9986 Oryctolagus cuniculus ENSOCUG00000021335 30611 Otolemur garnettii ENSOGAG00000003205
8128 Oreochromis niloticus ENSONIG00000006737 9978 Ochotona princeps ENSOPRG00000003507
8090 Oryzias latipes ENSORLG00000003951 9813 Procavia capensis ENSPCAG00000002201
7757 Petromyzon marinus ENSPMAG00000008313 132908 Pteropus vampyrus ENSPVAG00000001431
42254 Sorex araneus ENSSARG00000004470 9305 Sarcophilus harrisii ENSSHAG00000014034
37347 Tupaia belangeri ENSTBEG00000012820 59729 Taeniopygia guttata ENSTGUG00000006267
99883 Tetraodon nigroviridis ENSTNIG00000016258 9478 Tarsius syrichta ENSTSYG00000006328
9739 Tursiops truncatus ENSTTRG00000010327 30538 Vicugna pacos ENSVPAG00000004452
51511 Ciona savignyi ENSCSAVG00000000341 9031 Gallus gallus ENSGALG00000010745
10116 Rattus norvegicus ENSRNOG00000030351

Paralogs
3149