Basic Information
Gene ID 317734
Gene Name esr2a; erbeta2
Full Name Esr2a protein
Organism Danio rerio [7955]

Cross Reference
UniProt Q7ZU32 UniGene Dr.80416
PDB NULL OMIM NULL
KEGG dre:317734 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSDARP00000017514 Gene3D G3DSA:1.10.565.10 IPR008946 213 243 7.30e-80 Nuclear hormone receptor, ligand-binding
ENSDARP00000017514 Gene3D G3DSA:1.10.565.10 IPR008946 281 517 7.30e-80 Nuclear hormone receptor, ligand-binding
ENSDARP00000017514 Gene3D G3DSA:3.30.50.10 IPR013088 159 212 6.40e-28 Zinc finger, NHR/GATA-type
ENSDARP00000017514 Pfam PF00104 IPR000536 305 497 2.60e-30 Nuclear hormone receptor, ligand-binding, core
ENSDARP00000017514 Pfam PF00105 IPR001628 158 226 2.70e-31 Zinc finger, nuclear hormone receptor-type
ENSDARP00000017514 Pfam PF12497 IPR021064 28 134 1.20e-39 Estrogen receptor beta, N-terminal
ENSDARP00000017514 PIRSF PIRSF002527 IPR024178 38 550 0.00e-00 Oestrogen receptor/oestrogen-related receptor
ENSDARP00000017514 PIRSF PIRSF500102 IPR028355 1 553 0.00e-00 Estrogen receptor beta/gamma
ENSDARP00000017514 PRINTS PR00047 IPR001628 159 175 6.00e-17 Zinc finger, nuclear hormone receptor-type
ENSDARP00000017514 PRINTS PR00047 IPR001628 175 190 6.00e-17 Zinc finger, nuclear hormone receptor-type
ENSDARP00000017514 PRINTS PR00047 IPR001628 208 216 6.00e-17 Zinc finger, nuclear hormone receptor-type
ENSDARP00000017514 PRINTS PR00047 IPR001628 216 224 6.00e-17 Zinc finger, nuclear hormone receptor-type
ENSDARP00000017514 PRINTS PR00398 IPR001723 220 230 1.90e-25 Steroid hormone receptor
ENSDARP00000017514 PRINTS PR00398 IPR001723 319 340 1.90e-25 Steroid hormone receptor
ENSDARP00000017514 PRINTS PR00398 IPR001723 340 356 1.90e-25 Steroid hormone receptor
ENSDARP00000017514 PRINTS PR00398 IPR001723 408 423 1.90e-25 Steroid hormone receptor
ENSDARP00000017514 PRINTS PR00398 IPR001723 476 493 1.90e-25 Steroid hormone receptor
ENSDARP00000017514 ProSitePatterns PS00031 IPR001628 159 185 - Zinc finger, nuclear hormone receptor-type
ENSDARP00000017514 ProSiteProfiles PS51030 IPR001628 156 231 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSDARP00000017514 SMART SM00399 IPR001628 156 227 4.30e-37 Zinc finger, nuclear hormone receptor-type
ENSDARP00000017514 SMART SM00430 IPR000536 318 488 1.30e-38 Nuclear hormone receptor, ligand-binding, core
ENSDARP00000017514 SUPERFAMILY SSF48508 IPR008946 279 517 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSDARP00000017514 PF12497 5.5e-40 ERbeta_N Estrogen receptor beta
ENSDARP00000017514 PF00105 1.5e-31 zf-C4 Zinc finger, C4 type (two domains)
ENSDARP00000017514 PF00104 1.4e-30 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSDARP00000017514 GO:0006351 biological_process transcription, DNA-templated
ENSDARP00000017514 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSDARP00000017514 GO:0030520 biological_process intracellular estrogen receptor signaling pathway
ENSDARP00000017514 GO:0043401 biological_process steroid hormone mediated signaling pathway
ENSDARP00000017514 GO:0005634 cellular_component nucleus
ENSDARP00000017514 GO:0003677 molecular_function DNA binding
ENSDARP00000017514 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSDARP00000017514 GO:0003707 molecular_function steroid hormone receptor activity
ENSDARP00000017514 GO:0005496 molecular_function steroid binding
ENSDARP00000017514 GO:0008270 molecular_function zinc ion binding
ENSDARP00000017514 GO:0008289 molecular_function lipid binding
ENSDARP00000017514 GO:0030284 molecular_function estrogen receptor activity
ENSDARP00000017514 GO:0043565 molecular_function sequence-specific DNA binding
ENSDARP00000017514 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9796 Equus caballus 100033964 8090 Oryzias latipes 100049269
9601 Pongo abelii 100459579 10029 Cricetulus griseus 100763291
9597 Pan paniscus 100988122 8083 Xiphophorus maculatus 102232037
7897 Latimeria chalumnae 102366308 13735 Pelodiscus sinensis 102447875
10090 Mus musculus 13983 9555 Papio anubis 100303418
30611 Otolemur garnettii 100946964 39432 Saimiri boliviensis 101046392
9544 Macaca mulatta 574110 8128 Oreochromis niloticus ENSONIG00000005633
37347 Tupaia belangeri ENSTBEG00000001569 31033 Takifugu rubripes ENSTRUG00000013709
9615 Canis familiaris 403639 9598 Pan troglodytes 452964
9646 Ailuropoda melanoleuca ENSAMEG00000003956 9358 Choloepus hoffmanni ENSCHOG00000012987
9483 Callithrix jacchus ENSCJAG00000019502 10141 Cavia porcellus ENSCPOG00000005703
9361 Dasypus novemcinctus ENSDNOG00000013868 9365 Erinaceus europaeus ENSEEUG00000006141
9371 Echinops telfairi ENSETEG00000014544 9685 Felis catus ENSFCAG00000009636
69293 Gasterosteus aculeatus ENSGACG00000007514 9031 Gallus gallus ENSGALG00000011801
9595 Gorilla gorilla ENSGGOG00000003030 8049 Gadus morhua ENSGMOG00000019003
9785 Loxodonta africana ENSLAFG00000017799 9315 Macropus eugenii ENSMEUG00000008494
9103 Meleagris gallopavo ENSMGAG00000013507 30608 Microcebus murinus ENSMICG00000013003
59463 Myotis lucifugus ENSMLUG00000011894 13616 Monodelphis domestica ENSMODG00000009240
9669 Mustela putorius furo ENSMPUG00000006688 9258 Ornithorhynchus anatinus ENSOANG00000009109
9813 Procavia capensis ENSPCAG00000011157 7757 Petromyzon marinus ENSPMAG00000008530
132908 Pteropus vampyrus ENSPVAG00000017577 10116 Rattus norvegicus ENSRNOG00000005343
42254 Sorex araneus ENSSARG00000004498 9305 Sarcophilus harrisii ENSSHAG00000008174
9823 Sus scrofa ENSSSCG00000005109 43179 Ictidomys tridecemlineatus ENSSTOG00000015102
99883 Tetraodon nigroviridis ENSTNIG00000003064 9478 Tarsius syrichta ENSTSYG00000009621
9739 Tursiops truncatus ENSTTRG00000000517 30538 Vicugna pacos ENSVPAG00000004869
8364 Xenopus tropicalis ENSXETG00000007257