Basic Information
Gene ID ENSRNOG00000005343 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Esr2
Full Name Estrogen receptor beta
Organism Rattus norvegicus [10116]

Cross Reference
UniProt D3ZQD5 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSRNOP00000043144 Gene3D G3DSA:1.10.565.10 IPR008946 203 516 2.20e-75 Nuclear hormone receptor, ligand-binding
ENSRNOP00000043144 Gene3D G3DSA:3.30.50.10 IPR013088 149 202 6.30e-28 Zinc finger, NHR/GATA-type
ENSRNOP00000043144 Pfam PF00104 IPR000536 284 494 4.60e-33 Nuclear hormone receptor, ligand-binding, core
ENSRNOP00000043144 Pfam PF00105 IPR001628 148 216 3.80e-31 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000043144 Pfam PF12497 IPR021064 12 123 9.30e-39 Estrogen receptor beta, N-terminal
ENSRNOP00000043144 PIRSF PIRSF002527 IPR024178 23 548 2.10e-298 Oestrogen receptor/oestrogen-related receptor
ENSRNOP00000043144 PIRSF PIRSF500102 IPR028355 1 548 0.00e-00 Estrogen receptor beta/gamma
ENSRNOP00000043144 PRINTS PR00047 IPR001628 149 165 5.90e-17 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000043144 PRINTS PR00047 IPR001628 165 180 5.90e-17 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000043144 PRINTS PR00047 IPR001628 198 206 5.90e-17 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000043144 PRINTS PR00047 IPR001628 206 214 5.90e-17 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000043144 PRINTS PR00398 IPR001723 210 220 4.00e-24 Steroid hormone receptor
ENSRNOP00000043144 PRINTS PR00398 IPR001723 301 322 4.00e-24 Steroid hormone receptor
ENSRNOP00000043144 PRINTS PR00398 IPR001723 322 338 4.00e-24 Steroid hormone receptor
ENSRNOP00000043144 PRINTS PR00398 IPR001723 408 423 4.00e-24 Steroid hormone receptor
ENSRNOP00000043144 PRINTS PR00398 IPR001723 475 492 4.00e-24 Steroid hormone receptor
ENSRNOP00000043144 ProSitePatterns PS00031 IPR001628 149 175 - Zinc finger, nuclear hormone receptor-type
ENSRNOP00000043144 ProSiteProfiles PS51030 IPR001628 146 221 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000043144 SMART SM00399 IPR001628 146 217 5.90e-37 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000043144 SMART SM00430 IPR000536 300 487 3.50e-37 Nuclear hormone receptor, ligand-binding, core
ENSRNOP00000043144 SUPERFAMILY SSF48508 IPR008946 198 211 0.00e-00 Nuclear hormone receptor, ligand-binding
ENSRNOP00000043144 SUPERFAMILY SSF48508 IPR008946 253 517 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSRNOP00000043144 PF12497 4.4e-39 ERbeta_N Estrogen receptor beta
ENSRNOP00000043144 PF00104 2.9e-33 Hormone_recep Ligand-binding domain of nuclear hormone receptor
ENSRNOP00000043144 PF00105 1.5e-31 zf-C4 Zinc finger, C4 type (two domains)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSRNOP00000043144 GO:0006351 biological_process transcription, DNA-templated
ENSRNOP00000043144 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSRNOP00000043144 GO:0030520 biological_process intracellular estrogen receptor signaling pathway
ENSRNOP00000043144 GO:0005634 cellular_component nucleus
ENSRNOP00000043144 GO:0003677 molecular_function DNA binding
ENSRNOP00000043144 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSRNOP00000043144 GO:0003707 molecular_function steroid hormone receptor activity
ENSRNOP00000043144 GO:0005496 molecular_function steroid binding
ENSRNOP00000043144 GO:0008270 molecular_function zinc ion binding
ENSRNOP00000043144 GO:0030284 molecular_function estrogen receptor activity
ENSRNOP00000043144 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9615 Canis familiaris 403639 9598 Pan troglodytes 452964
9646 Ailuropoda melanoleuca ENSAMEG00000003956 10141 Cavia porcellus ENSCPOG00000005703
9103 Meleagris gallopavo ENSMGAG00000013507 59463 Myotis lucifugus ENSMLUG00000011894
9669 Mustela putorius furo ENSMPUG00000006688 9796 Equus caballus 100033964
9555 Papio anubis 100303418 9601 Pongo abelii 100459579
8128 Oreochromis niloticus 100534556 10029 Cricetulus griseus 100763291
30611 Otolemur garnettii 100946964 9597 Pan paniscus 100988122
39432 Saimiri boliviensis 101046392 8083 Xiphophorus maculatus 102232037
7897 Latimeria chalumnae 102366308 13735 Pelodiscus sinensis 102447875
10090 Mus musculus 13983 7955 Danio rerio 317734
9544 Macaca mulatta 574110 9358 Choloepus hoffmanni ENSCHOG00000012987
9483 Callithrix jacchus ENSCJAG00000019502 9361 Dasypus novemcinctus ENSDNOG00000013868
10020 Dipodomys ordii ENSDORG00000010443 9365 Erinaceus europaeus ENSEEUG00000006141
9371 Echinops telfairi ENSETEG00000014544 9685 Felis catus ENSFCAG00000009636
69293 Gasterosteus aculeatus ENSGACG00000007514 9031 Gallus gallus ENSGALG00000011801
9595 Gorilla gorilla ENSGGOG00000003030 8049 Gadus morhua ENSGMOG00000019003
9785 Loxodonta africana ENSLAFG00000017799 9315 Macropus eugenii ENSMEUG00000008494
30608 Microcebus murinus ENSMICG00000013003 13616 Monodelphis domestica ENSMODG00000009240
9258 Ornithorhynchus anatinus ENSOANG00000009109 9978 Ochotona princeps ENSOPRG00000005700
8090 Oryzias latipes ENSORLG00000018012 9813 Procavia capensis ENSPCAG00000011157
7757 Petromyzon marinus ENSPMAG00000008530 132908 Pteropus vampyrus ENSPVAG00000017577
42254 Sorex araneus ENSSARG00000004498 9305 Sarcophilus harrisii ENSSHAG00000008174
43179 Ictidomys tridecemlineatus ENSSTOG00000015102 37347 Tupaia belangeri ENSTBEG00000001569
99883 Tetraodon nigroviridis ENSTNIG00000003064 31033 Takifugu rubripes ENSTRUG00000013709
30538 Vicugna pacos ENSVPAG00000004869 8364 Xenopus tropicalis ENSXETG00000007257
9823 Sus scrofa ENSSSCG00000005109 9478 Tarsius syrichta ENSTSYG00000009621
9739 Tursiops truncatus ENSTTRG00000000517