Basic Information
Gene ID 4654 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name MYOD1; BHLHC1, MYF3, MYOD
Full Name Myoblast determination protein 1
Organism Homo sapiens [9606]

Cross Reference
UniProt P15172 UniGene Hs.181768
PDB NULL OMIM 159970
KEGG hsa:4654 UCSC uc001mni.3

Protein Interactions
DIP DIP-704N
IntAct P15172
MINT MINT-128965
STRING 9606.ENSP00000250003

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000250003 Gene3D G3DSA:4.10.280.10 IPR011598 100 165 1.60e-29 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000250003 Pfam PF00010 IPR011598 110 161 5.60e-15 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000250003 Pfam PF01586 IPR002546 22 109 6.00e-28 Myogenic basic muscle-specific protein
ENSP00000250003 Pfam PF12232 IPR022032 191 259 2.00e-26 Myogenic determination factor 5
ENSP00000250003 ProSiteProfiles PS50888 IPR011598 109 160 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000250003 SMART SM00353 IPR011598 115 166 5.00e-18 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000250003 SMART SM00520 IPR002546 1 114 1.70e-63 Myogenic basic muscle-specific protein
ENSP00000250003 SUPERFAMILY SSF47459 IPR011598 108 170 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000250003 PF01586 2.6e-28 Basic Myogenic Basic domain
ENSP00000250003 PF12232 7.1e-27 Myf5 Myogenic determination factor 5
ENSP00000250003 PF00010 3.2e-15 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000250003 GO:0006351 biological_process transcription, DNA-templated
ENSP00000250003 GO:0007517 biological_process muscle organ development
ENSP00000250003 GO:0043966 biological_process histone H3 acetylation
ENSP00000250003 GO:0043967 biological_process histone H4 acetylation
ENSP00000250003 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSP00000250003 GO:0071392 biological_process cellular response to estradiol stimulus
ENSP00000250003 GO:0005634 cellular_component nucleus
ENSP00000250003 GO:0005667 cellular_component transcription factor complex
ENSP00000250003 GO:0001047 molecular_function core promoter binding
ENSP00000250003 GO:0003677 molecular_function DNA binding
ENSP00000250003 GO:0031490 molecular_function chromatin DNA binding
ENSP00000250003 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9796 Equus caballus 100060703 9258 Ornithorhynchus anatinus 100073499
7425 Nasonia vitripennis 100123796 59729 Taeniopygia guttata 100232528
10224 Saccoglossus kowalevskii 100302710 9601 Pongo abelii 100451999
9646 Ailuropoda melanoleuca 100483494 8128 Oreochromis niloticus 100534488
61853 Nomascus leucogenys 100605738 30195 Bombus terrestris 100642478
9785 Loxodonta africana 100674686 10141 Cavia porcellus 100717629
10029 Cricetulus griseus 100773160 7463 Apis florea 100867910
143995 Megachile rotundata 100875133 34638 Metaseiulus occidentalis 100904128
9597 Pan paniscus 100981988 9555 Papio anubis 101009599
39432 Saimiri boliviensis 101042924 9685 Felis catus 101097667
9595 Gorilla gorilla 101130809 9669 Mustela putorius furo 101682575
43179 Ictidomys tridecemlineatus 101966425 59463 Myotis lucifugus 102419839
13735 Pelodiscus sinensis 102459218 10090 Mus musculus 17877
9913 Bos taurus 281336 7955 Danio rerio 30513
7668 Strongylocentrotus purpuratus 373197 7227 Drosophila melanogaster 42799
31033 Takifugu rubripes 446036 13616 Monodelphis domestica 100013522
132113 Bombus impatiens 100745308 9305 Sarcophilus harrisii 100923982
30611 Otolemur garnettii 100941493 9358 Choloepus hoffmanni ENSCHOG00000008319
9371 Echinops telfairi ENSETEG00000003979 69293 Gasterosteus aculeatus ENSGACG00000008444
9598 Pan troglodytes 467081 9615 Canis familiaris 611940
7070 Tribolium castaneum 660723 9544 Macaca mulatta 697306
28377 Anolis carolinensis ENSACAG00000014431 7719 Ciona intestinalis ENSCING00000007328
9483 Callithrix jacchus ENSCJAG00000019340 51511 Ciona savignyi ENSCSAVG00000002947
9361 Dasypus novemcinctus ENSDNOG00000017164 10020 Dipodomys ordii ENSDORG00000015437
9365 Erinaceus europaeus ENSEEUG00000011612 9031 Gallus gallus ENSGALG00000006216
8049 Gadus morhua ENSGMOG00000011389 7897 Latimeria chalumnae ENSLACG00000014430
9315 Macropus eugenii ENSMEUG00000014270 9103 Meleagris gallopavo ENSMGAG00000007210
30608 Microcebus murinus ENSMICG00000005566 9986 Oryctolagus cuniculus ENSOCUG00000021405
9978 Ochotona princeps ENSOPRG00000002390 8090 Oryzias latipes ENSORLG00000000694
9813 Procavia capensis ENSPCAG00000001317 132908 Pteropus vampyrus ENSPVAG00000012829
10116 Rattus norvegicus ENSRNOG00000011306 42254 Sorex araneus ENSSARG00000002401
9823 Sus scrofa ENSSSCG00000013375 37347 Tupaia belangeri ENSTBEG00000003438
99883 Tetraodon nigroviridis ENSTNIG00000002808 9478 Tarsius syrichta ENSTSYG00000014042
9739 Tursiops truncatus ENSTTRG00000013869 30538 Vicugna pacos ENSVPAG00000001927
8364 Xenopus tropicalis ENSXETG00000001320 8083 Xiphophorus maculatus ENSXMAG00000007430