Basic Information
Gene ID 485744
Gene Name NKX2-2
Full Name Uncharacterized protein
Organism Canis familiaris [9615]

Cross Reference
UniProt E2RNP4 UniGene NULL
PDB NULL OMIM NULL
KEGG cfa:485744 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSCAFP00000007724 Gene3D G3DSA:1.10.10.60 IPR009057 101 187 9.70e-26 Homeodomain-like
ENSCAFP00000007724 Pfam PF00046 IPR001356 129 185 8.80e-20 Homeobox domain
ENSCAFP00000007724 PRINTS PR00024 IPR020479 150 161 8.90e-06 Homeodomain, metazoa
ENSCAFP00000007724 PRINTS PR00024 IPR020479 165 175 8.90e-06 Homeodomain, metazoa
ENSCAFP00000007724 PRINTS PR00024 IPR020479 175 184 8.90e-06 Homeodomain, metazoa
ENSCAFP00000007724 ProSitePatterns PS00027 IPR017970 161 184 - Homeobox, conserved site
ENSCAFP00000007724 ProSiteProfiles PS50071 IPR001356 126 186 0.00e-00 Homeobox domain
ENSCAFP00000007724 SMART SM00389 IPR001356 128 190 1.10e-24 Homeobox domain
ENSCAFP00000007724 SUPERFAMILY SSF46689 IPR009057 116 186 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSCAFP00000007724 PF00046 4.6e-20 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSCAFP00000007724 GO:0007275 biological_process multicellular organismal development
ENSCAFP00000007724 GO:0005634 cellular_component nucleus
ENSCAFP00000007724 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSCAFP00000007724 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
8364 Xenopus tropicalis 100038077 9796 Equus caballus 100050029
7425 Nasonia vitripennis 100120954 30195 Bombus terrestris 100648138
132113 Bombus impatiens 100741206 143995 Megachile rotundata 100882499
9685 Felis catus 101083926 9595 Gorilla gorilla 101138484
9669 Mustela putorius furo 101682380 7955 Danio rerio 30697
59729 Taeniopygia guttata 100226749 10224 Saccoglossus kowalevskii 100303532
34638 Metaseiulus occidentalis 100906762 9305 Sarcophilus harrisii 100918079
30611 Otolemur garnettii 100942745 9597 Pan paniscus 100981941
9555 Papio anubis 101009557 39432 Saimiri boliviensis 101047273
43179 Ictidomys tridecemlineatus 101959936 8083 Xiphophorus maculatus 102227328
7227 Drosophila melanogaster 31003 7460 Apis mellifera 725671
9646 Ailuropoda melanoleuca ENSAMEG00000012637 9365 Erinaceus europaeus ENSEEUG00000000616
9371 Echinops telfairi ENSETEG00000010501 8049 Gadus morhua ENSGMOG00000018920
30608 Microcebus murinus ENSMICG00000016966 59463 Myotis lucifugus ENSMLUG00000009371
31033 Takifugu rubripes ENSTRUG00000007981 9913 Bos taurus 531695
7668 Strongylocentrotus purpuratus 579092 7070 Tribolium castaneum 656094
10020 Dipodomys ordii ENSDORG00000007972 69293 Gasterosteus aculeatus ENSGACG00000006996
7897 Latimeria chalumnae ENSLACG00000002767 9315 Macropus eugenii ENSMEUG00000014506
9258 Ornithorhynchus anatinus ENSOANG00000002007 8128 Oreochromis niloticus ENSONIG00000008139
8090 Oryzias latipes ENSORLG00000017414 9813 Procavia capensis ENSPCAG00000008298
13735 Pelodiscus sinensis ENSPSIG00000015250 37347 Tupaia belangeri ENSTBEG00000015943
99883 Tetraodon nigroviridis ENSTNIG00000016892 9739 Tursiops truncatus ENSTTRG00000009146