Basic Information
Gene ID 58092
Gene Name smad3a
Full Name MAD homolog 3a (Drosophila)
Organism Danio rerio [7955]

Cross Reference
UniProt Q8AY15 UniGene Dr.87309
PDB NULL OMIM NULL
KEGG dre:58092 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 7955.ENSDARP00000045373

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSDARP00000045373 Gene3D G3DSA:2.60.200.10 IPR017855 224 425 6.60e-99 SMAD domain-like
ENSDARP00000045373 Gene3D G3DSA:3.90.520.10 IPR013019 2 142 1.00e-64 MAD homology, MH1
ENSDARP00000045373 PANTHER PTHR13703 IPR013790 1 425 0.00e-00 Dwarfin
ENSDARP00000045373 Pfam PF03165 IPR003619 30 130 4.30e-44 MAD homology 1, Dwarfin-type
ENSDARP00000045373 Pfam PF03166 IPR001132 227 402 3.70e-77 SMAD domain, Dwarfin-type
ENSDARP00000045373 ProSiteProfiles PS51075 IPR013019 9 135 0.00e-00 MAD homology, MH1
ENSDARP00000045373 ProSiteProfiles PS51076 IPR001132 232 425 0.00e-00 SMAD domain, Dwarfin-type
ENSDARP00000045373 SMART SM00523 IPR003619 25 133 1.30e-70 MAD homology 1, Dwarfin-type
ENSDARP00000045373 SMART SM00524 IPR001132 230 401 3.30e-111 SMAD domain, Dwarfin-type
ENSDARP00000045373 SUPERFAMILY SSF49879 IPR008984 176 416 0.00e-00 SMAD/FHA domain
ENSDARP00000045373 SUPERFAMILY SSF56366 IPR013019 9 130 0.00e-00 MAD homology, MH1

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSDARP00000045373 PF03166 0 MH2 MH2 domain
ENSDARP00000045373 PF03165 2.24208e-44 MH1 MH1 domain
ENSDARP00000045373 PF10401 5.9e-05 IRF-3 Interferon-regulatory factor 3

Gene Ontology Annotation
Protein Entry Name Space Description
ENSDARP00000045373 GO:0006351 biological_process transcription, DNA-templated
ENSDARP00000045373 GO:0007179 biological_process transforming growth factor beta receptor signaling pathway
ENSDARP00000045373 GO:0005634 cellular_component nucleus
ENSDARP00000045373 GO:0005667 cellular_component transcription factor complex
ENSDARP00000045373 GO:0005737 cellular_component cytoplasm
ENSDARP00000045373 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100114895 10224 Saccoglossus kowalevskii 100313734
9483 Callithrix jacchus 100393808 9601 Pongo abelii 100448249
30195 Bombus terrestris 100646575 132113 Bombus impatiens 100740756
10029 Cricetulus griseus 100771578 7463 Apis florea 100864028
143995 Megachile rotundata 100882571 34638 Metaseiulus occidentalis 100906659
9597 Pan paniscus 100993322 9555 Papio anubis 101013089
39432 Saimiri boliviensis 101039593 9685 Felis catus 101087179
9669 Mustela putorius furo 101691860 43179 Ictidomys tridecemlineatus 101973097
7897 Latimeria chalumnae 102360430 59463 Myotis lucifugus 102429768
13735 Pelodiscus sinensis 102457921 10116 Rattus norvegicus 25631
9606 Homo sapiens 4087 7460 Apis mellifera 412601
7668 Strongylocentrotus purpuratus 577345 9544 Macaca mulatta 711355
9598 Pan troglodytes 748161 9031 Gallus gallus 769000
7719 Ciona intestinalis 778756 28377 Anolis carolinensis ENSACAG00000009914
9646 Ailuropoda melanoleuca ENSAMEG00000003318 9913 Bos taurus ENSBTAG00000012599
9615 Canis familiaris ENSCAFG00000017388 9358 Choloepus hoffmanni ENSCHOG00000011289
10141 Cavia porcellus ENSCPOG00000021314 51511 Ciona savignyi ENSCSAVG00000004749
10020 Dipodomys ordii ENSDORG00000013015 9796 Equus caballus ENSECAG00000015132
9365 Erinaceus europaeus ENSEEUG00000007736 69293 Gasterosteus aculeatus ENSGACG00000005092
9595 Gorilla gorilla ENSGGOG00000004706 8049 Gadus morhua ENSGMOG00000008364
9785 Loxodonta africana ENSLAFG00000021903 9103 Meleagris gallopavo ENSMGAG00000009879
30608 Microcebus murinus ENSMICG00000006119 13616 Monodelphis domestica ENSMODG00000009609
61853 Nomascus leucogenys ENSNLEG00000012983 9258 Ornithorhynchus anatinus ENSOANG00000013558
8128 Oreochromis niloticus ENSONIG00000013271 9978 Ochotona princeps ENSOPRG00000014996
8090 Oryzias latipes ENSORLG00000002207 9813 Procavia capensis ENSPCAG00000008103
7757 Petromyzon marinus ENSPMAG00000000489 132908 Pteropus vampyrus ENSPVAG00000002626
9823 Sus scrofa ENSSSCG00000004505 37347 Tupaia belangeri ENSTBEG00000016121
59729 Taeniopygia guttata ENSTGUG00000000016 99883 Tetraodon nigroviridis ENSTNIG00000009546
31033 Takifugu rubripes ENSTRUG00000016858 9478 Tarsius syrichta ENSTSYG00000005303
9739 Tursiops truncatus ENSTTRG00000002628 30538 Vicugna pacos ENSVPAG00000007781
8364 Xenopus tropicalis ENSXETG00000020292 8083 Xiphophorus maculatus ENSXMAG00000002377
9371 Echinops telfairi ENSETEG00000003356 9315 Macropus eugenii ENSMEUG00000016668
9305 Sarcophilus harrisii ENSSHAG00000012543

Paralogs
ENSDARG00000010207