Basic Information
Gene ID 100448249
Gene Name SMAD3
Full Name Uncharacterized protein
Organism Pongo abelii [9601]

Cross Reference
UniProt H2NNK3 UniGene NULL
PDB NULL OMIM NULL
KEGG pon:100448249 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPPYP00000007465 Gene3D G3DSA:2.60.200.10 IPR017855 224 425 8.10e-99 SMAD domain-like
ENSPPYP00000007465 Gene3D G3DSA:3.90.520.10 IPR013019 2 143 1.10e-64 MAD homology, MH1
ENSPPYP00000007465 PANTHER PTHR13703 IPR013790 1 425 0.00e-00 Dwarfin
ENSPPYP00000007465 Pfam PF03165 IPR003619 31 131 1.20e-43 MAD homology 1, Dwarfin-type
ENSPPYP00000007465 Pfam PF03166 IPR001132 227 402 2.20e-77 SMAD domain, Dwarfin-type
ENSPPYP00000007465 ProSiteProfiles PS51075 IPR013019 10 136 0.00e-00 MAD homology, MH1
ENSPPYP00000007465 ProSiteProfiles PS51076 IPR001132 232 425 0.00e-00 SMAD domain, Dwarfin-type
ENSPPYP00000007465 SMART SM00523 IPR003619 26 134 1.10e-70 MAD homology 1, Dwarfin-type
ENSPPYP00000007465 SMART SM00524 IPR001132 230 401 1.40e-111 SMAD domain, Dwarfin-type
ENSPPYP00000007465 SUPERFAMILY SSF49879 IPR008984 176 416 0.00e-00 SMAD/FHA domain
ENSPPYP00000007465 SUPERFAMILY SSF56366 IPR013019 10 131 0.00e-00 MAD homology, MH1

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPPYP00000007465 PF03166 0 MH2 MH2 domain
ENSPPYP00000007465 PF03165 6.16571e-44 MH1 MH1 domain
ENSPPYP00000007465 PF10401 6.5e-05 IRF-3 Interferon-regulatory factor 3

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPPYP00000007465 GO:0006351 biological_process transcription, DNA-templated
ENSPPYP00000007465 GO:0007179 biological_process transforming growth factor beta receptor signaling pathway
ENSPPYP00000007465 GO:0005634 cellular_component nucleus
ENSPPYP00000007465 GO:0005667 cellular_component transcription factor complex
ENSPPYP00000007465 GO:0005737 cellular_component cytoplasm
ENSPPYP00000007465 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100114895 7029 Acyrthosiphon pisum 100167170
6087 Hydra magnipapillata 100211577 10224 Saccoglossus kowalevskii 100313734
9986 Oryctolagus cuniculus 100342616 9483 Callithrix jacchus 100393808
30195 Bombus terrestris 100646575 132113 Bombus impatiens 100740756
7463 Apis florea 100864028 143995 Megachile rotundata 100882571
34638 Metaseiulus occidentalis 100906659 9597 Pan paniscus 100993322
9555 Papio anubis 101013089 39432 Saimiri boliviensis 101039593
43179 Ictidomys tridecemlineatus 101973097 10090 Mus musculus 17129
6239 Caenorhabditis elegans 176229 10116 Rattus norvegicus 25631
7227 Drosophila melanogaster 33529 7460 Apis mellifera 412601
7668 Strongylocentrotus purpuratus 577345 7070 Tribolium castaneum 659927
9544 Macaca mulatta 711355 9598 Pan troglodytes 748161
7719 Ciona intestinalis 778756 28377 Anolis carolinensis ENSACAG00000009914
9646 Ailuropoda melanoleuca ENSAMEG00000003318 9913 Bos taurus ENSBTAG00000012599
9615 Canis familiaris ENSCAFG00000017388 9358 Choloepus hoffmanni ENSCHOG00000001562
10141 Cavia porcellus ENSCPOG00000021314 51511 Ciona savignyi ENSCSAVG00000004749
9361 Dasypus novemcinctus ENSDNOG00000006004 69293 Gasterosteus aculeatus ENSGACG00000005092
8049 Gadus morhua ENSGMOG00000008364 9785 Loxodonta africana ENSLAFG00000021903
9103 Meleagris gallopavo ENSMGAG00000009879 30608 Microcebus murinus ENSMICG00000006119
13616 Monodelphis domestica ENSMODG00000009609 61853 Nomascus leucogenys ENSNLEG00000012983
9258 Ornithorhynchus anatinus ENSOANG00000013558 30611 Otolemur garnettii ENSOGAG00000002742
8128 Oreochromis niloticus ENSONIG00000013271 9978 Ochotona princeps ENSOPRG00000014996
8090 Oryzias latipes ENSORLG00000002207 9813 Procavia capensis ENSPCAG00000008103
7757 Petromyzon marinus ENSPMAG00000000489 132908 Pteropus vampyrus ENSPVAG00000002626
42254 Sorex araneus ENSSARG00000009234 59729 Taeniopygia guttata ENSTGUG00000009470
99883 Tetraodon nigroviridis ENSTNIG00000009546 31033 Takifugu rubripes ENSTRUG00000016858
8083 Xiphophorus maculatus ENSXMAG00000002377 400682 Amphimedon queenslandica 100639179
7955 Danio rerio 58092 9371 Echinops telfairi ENSETEG00000003356
9315 Macropus eugenii ENSMEUG00000016668 9305 Sarcophilus harrisii ENSSHAG00000012543

Paralogs
ENSPPYG00000009144