Basic Information
Gene ID 58146
Gene Name hey2; grl; zgc:136746
Full Name Hairy/enhancer-of-split related with YRPW motif protein 2
Organism Danio rerio [7955]

Cross Reference
UniProt Q9I9L0 UniGene Dr.81319
PDB NULL OMIM NULL
KEGG dre:58146 UCSC NULL

Protein Interactions
DIP DIP-46472N
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSDARP00000002357 Gene3D G3DSA:4.10.280.10 IPR011598 49 106 6.10e-20 Myc-type, basic helix-loop-helix (bHLH) domain
ENSDARP00000002357 Pfam PF00010 IPR011598 53 104 1.40e-17 Myc-type, basic helix-loop-helix (bHLH) domain
ENSDARP00000002357 Pfam PF07527 IPR003650 124 163 8.80e-14 Orange
ENSDARP00000002357 ProSiteProfiles PS50888 IPR011598 48 103 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSDARP00000002357 ProSiteProfiles PS51054 IPR003650 122 157 0.00e-00 Orange
ENSDARP00000002357 SMART SM00353 IPR011598 54 109 2.20e-18 Myc-type, basic helix-loop-helix (bHLH) domain
ENSDARP00000002357 SMART SM00511 IPR018352 119 166 7.60e-20 Orange subgroup
ENSDARP00000002357 SUPERFAMILY SSF47459 IPR011598 42 106 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSDARP00000002357 PF00010 7.8e-18 HLH Helix-loop-helix DNA-binding domain
ENSDARP00000002357 PF07527 4e-14 Hairy_orange Hairy Orange

Gene Ontology Annotation
Protein Entry Name Space Description
ENSDARP00000002357 GO:0007219 biological_process Notch signaling pathway
ENSDARP00000002357 GO:0005634 cellular_component nucleus
ENSDARP00000002357 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100119662 61853 Nomascus leucogenys 100587093
143995 Megachile rotundata 100877455 9305 Sarcophilus harrisii 100918295
43179 Ictidomys tridecemlineatus 101976281 7227 Drosophila melanogaster 35764
9796 Equus caballus 100073020 7029 Acyrthosiphon pisum 100169375
10224 Saccoglossus kowalevskii 100303559 9483 Callithrix jacchus 100395441
28377 Anolis carolinensis 100562001 7460 Apis mellifera 100577069
400682 Amphimedon queenslandica 100640672 30195 Bombus terrestris 100648331
9785 Loxodonta africana 100661585 8128 Oreochromis niloticus 100711035
132113 Bombus impatiens 100744110 10029 Cricetulus griseus 100755611
7463 Apis florea 100869544 34638 Metaseiulus occidentalis 100900811
9597 Pan paniscus 100986179 9555 Papio anubis 101023494
39432 Saimiri boliviensis 101050354 31033 Takifugu rubripes 101068985
9669 Mustela putorius furo 101691308 7897 Latimeria chalumnae 102346312
13735 Pelodiscus sinensis 102453728 10090 Mus musculus 15213
9606 Homo sapiens 23462 9913 Bos taurus 408005
7668 Strongylocentrotus purpuratus 578414 7070 Tribolium castaneum 656543
9544 Macaca mulatta 712988 9646 Ailuropoda melanoleuca ENSAMEG00000009592
9615 Canis familiaris ENSCAFG00000008391 10141 Cavia porcellus ENSCPOG00000021417
10020 Dipodomys ordii ENSDORG00000009001 9365 Erinaceus europaeus ENSEEUG00000014040
9371 Echinops telfairi ENSETEG00000007340 9685 Felis catus ENSFCAG00000026914
69293 Gasterosteus aculeatus ENSGACG00000003436 9595 Gorilla gorilla ENSGGOG00000002589
8049 Gadus morhua ENSGMOG00000013488 9315 Macropus eugenii ENSMEUG00000008397
9103 Meleagris gallopavo ENSMGAG00000013281 30608 Microcebus murinus ENSMICG00000014068
59463 Myotis lucifugus ENSMLUG00000002617 9986 Oryctolagus cuniculus ENSOCUG00000016568
9978 Ochotona princeps ENSOPRG00000003055 9813 Procavia capensis ENSPCAG00000006105
9601 Pongo abelii ENSPPYG00000018693 9598 Pan troglodytes ENSPTRG00000020364
132908 Pteropus vampyrus ENSPVAG00000002976 42254 Sorex araneus ENSSARG00000011755
37347 Tupaia belangeri ENSTBEG00000008836 59729 Taeniopygia guttata ENSTGUG00000011792
99883 Tetraodon nigroviridis ENSTNIG00000017785 9739 Tursiops truncatus ENSTTRG00000016350
8364 Xenopus tropicalis ENSXETG00000021844 9031 Gallus gallus ENSGALG00000027364
8090 Oryzias latipes ENSORLG00000012953 10116 Rattus norvegicus ENSRNOG00000011593
30538 Vicugna pacos ENSVPAG00000010498 8083 Xiphophorus maculatus ENSXMAG00000003593

Paralogs
335134