Basic Information
Gene ID 705369
Gene Name SETD3; EGK_18532
Full Name Histone-lysine N-methyltransferase setd3 isoform a
Organism Macaca mulatta [9544]

Cross Reference
UniProt F7DAH4 UniGene Mmu.21122
PDB NULL OMIM NULL
KEGG mcc:705369 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMMUP00000001602 Gene3D G3DSA:3.90.1420.10 IPR015353 330 504 7.80e-58 Rubisco LSMT, substrate-binding domain
ENSMMUP00000001602 Pfam PF00856 IPR001214 105 314 2.30e-11 SET domain
ENSMMUP00000001602 Pfam PF09273 IPR015353 343 475 1.10e-37 Rubisco LSMT, substrate-binding domain
ENSMMUP00000001602 ProSiteProfiles PS50280 IPR001214 94 314 0.00e-00 SET domain
ENSMMUP00000001602 ProSiteProfiles PS51565 IPR025785 1 595 0.00e-00 Histone-lysine N-methyltransferase, SETD3
ENSMMUP00000001602 SUPERFAMILY SSF81822 IPR015353 337 519 0.00e-00 Rubisco LSMT, substrate-binding domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMMUP00000001602 PF09273 4.5e-38 Rubis-subs-bind Rubisco LSMT substrate-binding
ENSMMUP00000001602 PF00856 6.7e-12 SET SET domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMMUP00000001602 GO:0006351 biological_process transcription, DNA-templated
ENSMMUP00000001602 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSMMUP00000001602 GO:0010452 biological_process histone H3-K36 methylation
ENSMMUP00000001602 GO:0016568 biological_process chromatin modification
ENSMMUP00000001602 GO:0018022 biological_process peptidyl-lysine methylation
ENSMMUP00000001602 GO:0018023 biological_process peptidyl-lysine trimethylation
ENSMMUP00000001602 GO:0018026 biological_process peptidyl-lysine monomethylation
ENSMMUP00000001602 GO:0018027 biological_process peptidyl-lysine dimethylation
ENSMMUP00000001602 GO:0032259 biological_process methylation
ENSMMUP00000001602 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSMMUP00000001602 GO:0005634 cellular_component nucleus
ENSMMUP00000001602 GO:0003713 molecular_function transcription coactivator activity
ENSMMUP00000001602 GO:0008168 molecular_function methyltransferase activity
ENSMMUP00000001602 GO:0016740 molecular_function transferase activity
ENSMMUP00000001602 GO:0018024 molecular_function histone-lysine N-methyltransferase activity
ENSMMUP00000001602 GO:0046975 molecular_function histone methyltransferase activity (H3-K36 specific)

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100123991 7029 Acyrthosiphon pisum 100161611
59729 Taeniopygia guttata 100228706 30195 Bombus terrestris 100648643
132113 Bombus impatiens 100740861 7463 Apis florea 100870337
143995 Megachile rotundata 100878381 34638 Metaseiulus occidentalis 100898757
9597 Pan paniscus 100977239 8083 Xiphophorus maculatus 102233827
13735 Pelodiscus sinensis 102447925 6239 Caenorhabditis elegans 190607
7227 Drosophila melanogaster 31638 8364 Xenopus tropicalis 549331
7070 Tribolium castaneum 664524 9796 Equus caballus 100049970
9555 Papio anubis 100137585 28377 Anolis carolinensis 100565086
10029 Cricetulus griseus 100768717 30611 Otolemur garnettii 100966115
39432 Saimiri boliviensis 101047794 9669 Mustela putorius furo 101688373
10116 Rattus norvegicus 299295 10090 Mus musculus 52690
7668 Strongylocentrotus purpuratus 593983 9646 Ailuropoda melanoleuca ENSAMEG00000011420
9358 Choloepus hoffmanni ENSCHOG00000011590 51511 Ciona savignyi ENSCSAVG00000001659
7955 Danio rerio ENSDARG00000016513 9361 Dasypus novemcinctus ENSDNOG00000012617
9365 Erinaceus europaeus ENSEEUG00000003681 9595 Gorilla gorilla ENSGGOG00000011169
7897 Latimeria chalumnae ENSLACG00000013086 9103 Meleagris gallopavo ENSMGAG00000013257
30608 Microcebus murinus ENSMICG00000015065 9986 Oryctolagus cuniculus ENSOCUG00000012829
8128 Oreochromis niloticus ENSONIG00000011057 132908 Pteropus vampyrus ENSPVAG00000007426
9823 Sus scrofa ENSSSCG00000002508 43179 Ictidomys tridecemlineatus ENSSTOG00000006730
37347 Tupaia belangeri ENSTBEG00000012886 99883 Tetraodon nigroviridis ENSTNIG00000008284
31033 Takifugu rubripes ENSTRUG00000003791 30538 Vicugna pacos ENSVPAG00000009314
9606 Homo sapiens 84193 9615 Canis familiaris ENSCAFG00000017821
7719 Ciona intestinalis ENSCING00000004735 9483 Callithrix jacchus ENSCJAG00000006717
10020 Dipodomys ordii ENSDORG00000013141 9685 Felis catus ENSFCAG00000001108
69293 Gasterosteus aculeatus ENSGACG00000013126 9031 Gallus gallus ENSGALG00000026002
8049 Gadus morhua ENSGMOG00000015875 9785 Loxodonta africana ENSLAFG00000018555
9315 Macropus eugenii ENSMEUG00000003402 59463 Myotis lucifugus ENSMLUG00000012483
13616 Monodelphis domestica ENSMODG00000012975 9258 Ornithorhynchus anatinus ENSOANG00000014774
9978 Ochotona princeps ENSOPRG00000012636 9813 Procavia capensis ENSPCAG00000004920
7757 Petromyzon marinus ENSPMAG00000004272 9478 Tarsius syrichta ENSTSYG00000000725
9739 Tursiops truncatus ENSTTRG00000017132