Basic Information
Gene ID 84193 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name SETD3; C14orf154
Full Name Histone-lysine N-methyltransferase setd3
Organism Homo sapiens [9606]

Cross Reference
UniProt Q86TU7 UniGene Hs.510407
PDB 3SMT OMIM NULL
KEGG hsa:84193 UCSC uc021sbn.1

Protein Interactions
DIP NULL
IntAct Q86TU7
MINT NULL
STRING 9606.ENSP00000327436

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000327436 Gene3D G3DSA:3.90.1420.10 IPR015353 330 504 4.40e-58 Rubisco LSMT, substrate-binding domain
ENSP00000327436 Pfam PF00856 IPR001214 105 314 2.30e-11 SET domain
ENSP00000327436 Pfam PF09273 IPR015353 343 475 3.70e-37 Rubisco LSMT, substrate-binding domain
ENSP00000327436 ProSiteProfiles PS50280 IPR001214 94 314 0.00e-00 SET domain
ENSP00000327436 ProSiteProfiles PS51565 IPR025785 1 594 0.00e-00 Histone-lysine N-methyltransferase, SETD3
ENSP00000327436 SUPERFAMILY SSF81822 IPR015353 337 519 0.00e-00 Rubisco LSMT, substrate-binding domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000327436 PF09273 1.6e-37 Rubis-subs-bind Rubisco LSMT substrate-binding
ENSP00000327436 PF00856 4.3e-12 SET SET domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000327436 GO:0006351 biological_process transcription, DNA-templated
ENSP00000327436 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000327436 GO:0010452 biological_process histone H3-K36 methylation
ENSP00000327436 GO:0016568 biological_process chromatin modification
ENSP00000327436 GO:0018022 biological_process peptidyl-lysine methylation
ENSP00000327436 GO:0018023 biological_process peptidyl-lysine trimethylation
ENSP00000327436 GO:0018026 biological_process peptidyl-lysine monomethylation
ENSP00000327436 GO:0018027 biological_process peptidyl-lysine dimethylation
ENSP00000327436 GO:0032259 biological_process methylation
ENSP00000327436 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSP00000327436 GO:0005634 cellular_component nucleus
ENSP00000327436 GO:0003713 molecular_function transcription coactivator activity
ENSP00000327436 GO:0008168 molecular_function methyltransferase activity
ENSP00000327436 GO:0016740 molecular_function transferase activity
ENSP00000327436 GO:0018024 molecular_function histone-lysine N-methyltransferase activity
ENSP00000327436 GO:0046975 molecular_function histone methyltransferase activity (H3-K36 specific)

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100123991 59729 Taeniopygia guttata 100228706
132113 Bombus impatiens 100740861 143995 Megachile rotundata 100878381
9597 Pan paniscus 100977239 8364 Xenopus tropicalis 549331
9796 Equus caballus 100049970 9555 Papio anubis 100137585
7029 Acyrthosiphon pisum 100161611 28377 Anolis carolinensis 100565086
30195 Bombus terrestris 100648643 10029 Cricetulus griseus 100768717
7463 Apis florea 100870337 34638 Metaseiulus occidentalis 100898757
30611 Otolemur garnettii 100966115 39432 Saimiri boliviensis 101047794
9669 Mustela putorius furo 101688373 8083 Xiphophorus maculatus 102233827
13735 Pelodiscus sinensis 102447925 6239 Caenorhabditis elegans 190607
10116 Rattus norvegicus 299295 7227 Drosophila melanogaster 31638
10090 Mus musculus 52690 7668 Strongylocentrotus purpuratus 593983
7070 Tribolium castaneum 664524 9544 Macaca mulatta 705369
9646 Ailuropoda melanoleuca ENSAMEG00000011420 9358 Choloepus hoffmanni ENSCHOG00000011590
51511 Ciona savignyi ENSCSAVG00000001659 7955 Danio rerio ENSDARG00000016513
9361 Dasypus novemcinctus ENSDNOG00000012617 9365 Erinaceus europaeus ENSEEUG00000003681
9595 Gorilla gorilla ENSGGOG00000011169 7897 Latimeria chalumnae ENSLACG00000013086
9785 Loxodonta africana ENSLAFG00000018555 9103 Meleagris gallopavo ENSMGAG00000013257
30608 Microcebus murinus ENSMICG00000015065 9258 Ornithorhynchus anatinus ENSOANG00000014774
9986 Oryctolagus cuniculus ENSOCUG00000012829 8128 Oreochromis niloticus ENSONIG00000011057
9813 Procavia capensis ENSPCAG00000004920 7757 Petromyzon marinus ENSPMAG00000004272
132908 Pteropus vampyrus ENSPVAG00000007426 9823 Sus scrofa ENSSSCG00000002508
43179 Ictidomys tridecemlineatus ENSSTOG00000006730 37347 Tupaia belangeri ENSTBEG00000012886
99883 Tetraodon nigroviridis ENSTNIG00000008284 31033 Takifugu rubripes ENSTRUG00000003791
9478 Tarsius syrichta ENSTSYG00000000725 9739 Tursiops truncatus ENSTTRG00000017132
30538 Vicugna pacos ENSVPAG00000009314 9615 Canis familiaris ENSCAFG00000017821
7719 Ciona intestinalis ENSCING00000004735 9483 Callithrix jacchus ENSCJAG00000006717
10020 Dipodomys ordii ENSDORG00000013141 9685 Felis catus ENSFCAG00000001108
69293 Gasterosteus aculeatus ENSGACG00000013126 9031 Gallus gallus ENSGALG00000026002
8049 Gadus morhua ENSGMOG00000015875 9315 Macropus eugenii ENSMEUG00000003402
59463 Myotis lucifugus ENSMLUG00000012483 13616 Monodelphis domestica ENSMODG00000012975
9978 Ochotona princeps ENSOPRG00000012636