Basic Information
Gene ID 7566 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name ZNF18; HDSG1, KOX11, ZKSCAN6, ZNF535
Full Name Zinc finger protein 18
Organism Homo sapiens [9606]

Cross Reference
UniProt P17022 UniGene Hs.370473
PDB NULL OMIM 194524
KEGG hsa:7566 UCSC uc002gni.1

Protein Interactions
DIP NULL
IntAct P17022
MINT NULL
STRING 9606.ENSP00000315664

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000315664 Gene3D G3DSA:3.30.160.60 IPR013087 410 438 3.60e-11 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315664 Gene3D G3DSA:3.30.160.60 IPR013087 439 465 1.20e-12 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315664 Gene3D G3DSA:3.30.160.60 IPR013087 466 490 1.30e-13 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315664 Gene3D G3DSA:3.30.160.60 IPR013087 491 511 4.20e-17 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315664 Gene3D G3DSA:3.30.160.60 IPR013087 512 546 2.90e-17 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315664 PANTHER PTHR10032 IPR027775 1 549 0.00e-00 C2H2- zinc finger protein family
ENSP00000315664 PANTHER PTHR10032:SF11 IPR027764 1 549 0.00e-00 Zinc finger protein 18
ENSP00000315664 Pfam PF01352 IPR001909 222 249 1.50e-08 Krueppel-associated box
ENSP00000315664 Pfam PF02023 IPR003309 36 128 6.60e-40 Transcription regulator SCAN
ENSP00000315664 ProSitePatterns PS00028 IPR007087 410 430 - Zinc finger, C2H2
ENSP00000315664 ProSitePatterns PS00028 IPR007087 438 458 - Zinc finger, C2H2
ENSP00000315664 ProSitePatterns PS00028 IPR007087 464 486 - Zinc finger, C2H2
ENSP00000315664 ProSitePatterns PS00028 IPR007087 494 514 - Zinc finger, C2H2
ENSP00000315664 ProSitePatterns PS00028 IPR007087 522 542 - Zinc finger, C2H2
ENSP00000315664 ProSiteProfiles PS50157 IPR007087 408 435 0.00e-00 Zinc finger, C2H2
ENSP00000315664 ProSiteProfiles PS50157 IPR007087 436 463 0.00e-00 Zinc finger, C2H2
ENSP00000315664 ProSiteProfiles PS50157 IPR007087 464 491 0.00e-00 Zinc finger, C2H2
ENSP00000315664 ProSiteProfiles PS50157 IPR007087 492 519 0.00e-00 Zinc finger, C2H2
ENSP00000315664 ProSiteProfiles PS50157 IPR007087 520 547 0.00e-00 Zinc finger, C2H2
ENSP00000315664 ProSiteProfiles PS50804 IPR003309 41 120 0.00e-00 Transcription regulator SCAN
ENSP00000315664 ProSiteProfiles PS50805 IPR001909 211 283 0.00e-00 Krueppel-associated box
ENSP00000315664 SMART SM00349 IPR001909 222 272 2.80e-05 Krueppel-associated box
ENSP00000315664 SMART SM00355 IPR015880 408 430 3.70e-04 Zinc finger, C2H2-like
ENSP00000315664 SMART SM00355 IPR015880 436 458 8.10e-06 Zinc finger, C2H2-like
ENSP00000315664 SMART SM00355 IPR015880 464 486 5.70e-05 Zinc finger, C2H2-like
ENSP00000315664 SMART SM00355 IPR015880 492 514 8.30e-08 Zinc finger, C2H2-like
ENSP00000315664 SMART SM00355 IPR015880 520 542 2.60e-07 Zinc finger, C2H2-like
ENSP00000315664 SMART SM00431 IPR003309 37 149 8.20e-65 Transcription regulator SCAN
ENSP00000315664 SUPERFAMILY SSF109640 IPR001909 222 265 0.00e-00 Krueppel-associated box
ENSP00000315664 SUPERFAMILY SSF47353 IPR008916 36 123 0.00e-00 Retrovirus capsid, C-terminal

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000315664 PF02023 6.6e-40 SCAN SCAN domain
ENSP00000315664 PF13465 1e-36 zf-H2C2_2 Zinc-finger double domain
ENSP00000315664 PF00096 9.1e-27 zf-C2H2 Zinc finger, C2H2 type
ENSP00000315664 PF13894 1.8e-16 zf-C2H2_4 C2H2-type zinc finger
ENSP00000315664 PF01352 4.2e-09 KRAB KRAB box
ENSP00000315664 PF12171 2.1e-08 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding
ENSP00000315664 PF05605 1.8e-05 zf-Di19 Drought induced 19 protein (Di19), zinc-binding
ENSP00000315664 PF13912 1.9e-05 zf-C2H2_6 C2H2-type zinc finger

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000315664 GO:0005634 cellular_component nucleus
ENSP00000315664 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus 100386522 10029 Cricetulus griseus 100768111
9555 Papio anubis 101015083 9669 Mustela putorius furo 101673786
10116 Rattus norvegicus 303226 9615 Canis familiaris 479505
10090 Mus musculus 52712 30611 Otolemur garnettii 100946405
9597 Pan paniscus 100991178 39432 Saimiri boliviensis 101037259
10141 Cavia porcellus ENSCPOG00000012793 9595 Gorilla gorilla ENSGGOG00000005431
59463 Myotis lucifugus ENSMLUG00000022865 9978 Ochotona princeps ENSOPRG00000011305
132908 Pteropus vampyrus ENSPVAG00000014085 9823 Sus scrofa ENSSSCG00000018014
43179 Ictidomys tridecemlineatus ENSSTOG00000012652 9478 Tarsius syrichta ENSTSYG00000006855
28377 Anolis carolinensis ENSACAG00000028206 9646 Ailuropoda melanoleuca ENSAMEG00000013156
9913 Bos taurus ENSBTAG00000004675 9358 Choloepus hoffmanni ENSCHOG00000001767
10020 Dipodomys ordii ENSDORG00000012359 9796 Equus caballus ENSECAG00000025164
9365 Erinaceus europaeus ENSEEUG00000011943 9371 Echinops telfairi ENSETEG00000000611
9685 Felis catus ENSFCAG00000027934 9785 Loxodonta africana ENSLAFG00000009028
30608 Microcebus murinus ENSMICG00000016196 9544 Macaca mulatta ENSMMUG00000018541
13616 Monodelphis domestica ENSMODG00000000157 9986 Oryctolagus cuniculus ENSOCUG00000010095
9813 Procavia capensis ENSPCAG00000002958 42254 Sorex araneus ENSSARG00000003073
9305 Sarcophilus harrisii ENSSHAG00000004742 37347 Tupaia belangeri ENSTBEG00000007103
9739 Tursiops truncatus ENSTTRG00000012317 30538 Vicugna pacos ENSVPAG00000007132