Basic Information
Gene ID 779756
Gene Name nr4a1
Full Name Nuclear receptor subfamily 4, group A, member 1
Organism Xenopus tropicalis [8364]

Cross Reference
UniProt Q0V9X8 UniGene Str.43980
PDB NULL OMIM NULL
KEGG xtr:779756 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 8364.ENSXETP00000001266

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSXETP00000001266 Gene3D G3DSA:1.10.565.10 IPR008946 308 571 3.30e-70 Nuclear hormone receptor, ligand-binding
ENSXETP00000001266 Gene3D G3DSA:3.30.50.10 IPR013088 245 307 1.70e-30 Zinc finger, NHR/GATA-type
ENSXETP00000001266 Pfam PF00104 IPR000536 373 553 4.70e-25 Nuclear hormone receptor, ligand-binding, core
ENSXETP00000001266 Pfam PF00105 IPR001628 245 313 7.90e-31 Zinc finger, nuclear hormone receptor-type
ENSXETP00000001266 PRINTS PR00047 IPR001628 246 262 4.00e-18 Zinc finger, nuclear hormone receptor-type
ENSXETP00000001266 PRINTS PR00047 IPR001628 262 277 4.00e-18 Zinc finger, nuclear hormone receptor-type
ENSXETP00000001266 PRINTS PR00047 IPR001628 295 303 4.00e-18 Zinc finger, nuclear hormone receptor-type
ENSXETP00000001266 PRINTS PR00047 IPR001628 303 311 4.00e-18 Zinc finger, nuclear hormone receptor-type
ENSXETP00000001266 PRINTS PR00398 IPR001723 307 317 1.20e-20 Steroid hormone receptor
ENSXETP00000001266 PRINTS PR00398 IPR001723 388 409 1.20e-20 Steroid hormone receptor
ENSXETP00000001266 PRINTS PR00398 IPR001723 409 425 1.20e-20 Steroid hormone receptor
ENSXETP00000001266 PRINTS PR00398 IPR001723 475 490 1.20e-20 Steroid hormone receptor
ENSXETP00000001266 PRINTS PR00398 IPR001723 533 550 1.20e-20 Steroid hormone receptor
ENSXETP00000001266 PRINTS PR01284 IPR003070 117 132 7.70e-111 Orphan nuclear receptor
ENSXETP00000001266 PRINTS PR01284 IPR003070 24 41 7.70e-111 Orphan nuclear receptor
ENSXETP00000001266 PRINTS PR01284 IPR003070 318 333 7.70e-111 Orphan nuclear receptor
ENSXETP00000001266 PRINTS PR01284 IPR003070 340 356 7.70e-111 Orphan nuclear receptor
ENSXETP00000001266 PRINTS PR01284 IPR003070 383 397 7.70e-111 Orphan nuclear receptor
ENSXETP00000001266 PRINTS PR01284 IPR003070 433 453 7.70e-111 Orphan nuclear receptor
ENSXETP00000001266 PRINTS PR01284 IPR003070 44 57 7.70e-111 Orphan nuclear receptor
ENSXETP00000001266 PRINTS PR01284 IPR003070 454 469 7.70e-111 Orphan nuclear receptor
ENSXETP00000001266 PRINTS PR01284 IPR003070 500 517 7.70e-111 Orphan nuclear receptor
ENSXETP00000001266 PRINTS PR01284 IPR003070 533 553 7.70e-111 Orphan nuclear receptor
ENSXETP00000001266 PRINTS PR01284 IPR003070 554 575 7.70e-111 Orphan nuclear receptor
ENSXETP00000001266 PRINTS PR01287 IPR003073 144 164 8.30e-05 Orphan nuclear receptor, NURR type
ENSXETP00000001266 PRINTS PR01287 IPR003073 329 346 8.30e-05 Orphan nuclear receptor, NURR type
ENSXETP00000001266 PRINTS PR01287 IPR003073 517 533 8.30e-05 Orphan nuclear receptor, NURR type
ENSXETP00000001266 PRINTS PR01287 IPR003073 99 116 8.30e-05 Orphan nuclear receptor, NURR type
ENSXETP00000001266 ProSitePatterns PS00031 IPR001628 246 272 - Zinc finger, nuclear hormone receptor-type
ENSXETP00000001266 ProSiteProfiles PS51030 IPR001628 243 318 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSXETP00000001266 SMART SM00399 IPR001628 243 314 1.30e-40 Zinc finger, nuclear hormone receptor-type
ENSXETP00000001266 SMART SM00430 IPR000536 387 545 3.00e-34 Nuclear hormone receptor, ligand-binding, core
ENSXETP00000001266 SUPERFAMILY SSF48508 IPR008946 317 575 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSXETP00000001266 PF00105 3.9e-31 zf-C4 Zinc finger, C4 type (two domains)
ENSXETP00000001266 PF00104 2.8e-25 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSXETP00000001266 GO:0005634 cellular_component nucleus
ENSXETP00000001266 GO:0005737 cellular_component cytoplasm
ENSXETP00000001266 GO:0003707 molecular_function steroid hormone receptor activity
ENSXETP00000001266 GO:0004879 molecular_function ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
ENSXETP00000001266 GO:0008270 molecular_function zinc ion binding
ENSXETP00000001266 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7070 Tribolium castaneum 100142491 7029 Acyrthosiphon pisum 100162780
9483 Callithrix jacchus 100409975 30195 Bombus terrestris 100642535
132113 Bombus impatiens 100741960 7463 Apis florea 100868712
143995 Megachile rotundata 100884030 34638 Metaseiulus occidentalis 100902028
9597 Pan paniscus 100976569 9555 Papio anubis 101021171
7897 Latimeria chalumnae 102364494 9606 Homo sapiens 3164
7227 Drosophila melanogaster 35332 9031 Gallus gallus 424320
7668 Strongylocentrotus purpuratus 581160 9823 Sus scrofa 100157120
10224 Saccoglossus kowalevskii 100373323 8128 Oreochromis niloticus 100709939
30611 Otolemur garnettii 100965317 39432 Saimiri boliviensis 101039973
9685 Felis catus 101097902 9669 Mustela putorius furo 101676286
8083 Xiphophorus maculatus 102231076 9544 Macaca mulatta 697077
9615 Canis familiaris ENSCAFG00000007338 10141 Cavia porcellus ENSCPOG00000003095
51511 Ciona savignyi ENSCSAVG00000004898 9365 Erinaceus europaeus ENSEEUG00000003127
69293 Gasterosteus aculeatus ENSGACG00000005831 9595 Gorilla gorilla ENSGGOG00000006418
8049 Gadus morhua ENSGMOG00000019215 9785 Loxodonta africana ENSLAFG00000013317
59463 Myotis lucifugus ENSMLUG00000006887 61853 Nomascus leucogenys ENSNLEG00000017763
9258 Ornithorhynchus anatinus ENSOANG00000006120 8090 Oryzias latipes ENSORLG00000016692
9813 Procavia capensis ENSPCAG00000003761 13735 Pelodiscus sinensis ENSPSIG00000018018
43179 Ictidomys tridecemlineatus ENSSTOG00000019650 10116 Rattus norvegicus 79240
9646 Ailuropoda melanoleuca ENSAMEG00000001755 9358 Choloepus hoffmanni ENSCHOG00000012702
7719 Ciona intestinalis ENSCING00000019110 9361 Dasypus novemcinctus ENSDNOG00000003671
10020 Dipodomys ordii ENSDORG00000000196 9796 Equus caballus ENSECAG00000016661
9371 Echinops telfairi ENSETEG00000018553 9315 Macropus eugenii ENSMEUG00000001112
30608 Microcebus murinus ENSMICG00000016812 9986 Oryctolagus cuniculus ENSOCUG00000011746
9978 Ochotona princeps ENSOPRG00000002948 9601 Pongo abelii ENSPPYG00000004537
132908 Pteropus vampyrus ENSPVAG00000004955 42254 Sorex araneus ENSSARG00000010811
9305 Sarcophilus harrisii ENSSHAG00000012643 37347 Tupaia belangeri ENSTBEG00000017058
59729 Taeniopygia guttata ENSTGUG00000016805 99883 Tetraodon nigroviridis ENSTNIG00000016484
31033 Takifugu rubripes ENSTRUG00000015503 9478 Tarsius syrichta ENSTSYG00000001482
9739 Tursiops truncatus ENSTTRG00000005740 30538 Vicugna pacos ENSVPAG00000000105