Basic Information
Gene ID ENSMEUG00000004666
Gene Name ENSMEUG00000004666
Full Name ENSMEUG00000004666
Organism Macropus eugenii [9315]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMEUP00000004257 Gene3D G3DSA:1.10.10.10 IPR011991 4 55 1.90e-11 Winged helix-turn-helix DNA-binding domain
ENSMEUP00000004257 Gene3D G3DSA:2.60.200.10 IPR017855 200 308 2.70e-23 SMAD domain-like
ENSMEUP00000004257 Pfam PF00605 IPR001346 8 56 9.20e-10 Interferon regulatory factor DNA-binding domain
ENSMEUP00000004257 Pfam PF10401 IPR019471 203 314 3.90e-19 Interferon regulatory factor-3
ENSMEUP00000004257 ProSiteProfiles PS51507 IPR001346 6 242 0.00e-00 Interferon regulatory factor DNA-binding domain
ENSMEUP00000004257 SUPERFAMILY SSF49879 IPR008984 204 307 0.00e-00 SMAD/FHA domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMEUP00000004257 PF10401 3e-19 IRF-3 Interferon-regulatory factor 3
ENSMEUP00000004257 PF00605 6.2e-10 IRF Interferon regulatory factor transcription factor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMEUP00000004257 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSMEUP00000004257 GO:0006351 biological_process transcription, DNA-templated
ENSMEUP00000004257 GO:0031663 biological_process lipopolysaccharide-mediated signaling pathway
ENSMEUP00000004257 GO:0032727 biological_process positive regulation of interferon-alpha production
ENSMEUP00000004257 GO:0032728 biological_process positive regulation of interferon-beta production
ENSMEUP00000004257 GO:0043330 biological_process response to exogenous dsRNA
ENSMEUP00000004257 GO:0045087 biological_process innate immune response
ENSMEUP00000004257 GO:0045351 biological_process type I interferon biosynthetic process
ENSMEUP00000004257 GO:0045358 biological_process negative regulation of interferon-beta biosynthetic process
ENSMEUP00000004257 GO:0050689 biological_process negative regulation of defense response to virus by host
ENSMEUP00000004257 GO:0051607 biological_process defense response to virus
ENSMEUP00000004257 GO:0060340 biological_process positive regulation of type I interferon-mediated signaling pathway
ENSMEUP00000004257 GO:0005634 cellular_component nucleus
ENSMEUP00000004257 GO:0005737 cellular_component cytoplasm
ENSMEUP00000004257 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMEUP00000004257 GO:0042803 molecular_function protein homodimerization activity
ENSMEUP00000004257 GO:0044212 molecular_function transcription regulatory region DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9606 Homo sapiens 3661 10141 Cavia porcellus ENSCPOG00000026146
10020 Dipodomys ordii ENSDORG00000014920 9595 Gorilla gorilla ENSGGOG00000000499
9785 Loxodonta africana ENSLAFG00000028074 13616 Monodelphis domestica ENSMODG00000013603
30608 Microcebus murinus ENSMICG00000001752 30611 Otolemur garnettii ENSOGAG00000011935
9813 Procavia capensis ENSPCAG00000008633 132908 Pteropus vampyrus ENSPVAG00000010968
9305 Sarcophilus harrisii ENSSHAG00000003813 37347 Tupaia belangeri ENSTBEG00000003466
9739 Tursiops truncatus ENSTTRG00000005531