Basic Information
Gene ID ENSRNOG00000018483 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Smad1; Mad1, Madh1
Full Name Mothers against decapentaplegic homolog 1
Organism Rattus norvegicus [10116]

Cross Reference
UniProt P97588 UniGene Rn.10635
PDB NULL OMIM NULL
KEGG NULL UCSC RGD:3030

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 10116.ENSRNOP00000025079

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSRNOP00000025079 Gene3D G3DSA:2.60.200.10 IPR017855 266 468 1.30e-97 SMAD domain-like
ENSRNOP00000025079 Gene3D G3DSA:3.90.520.10 IPR013019 5 144 2.30e-61 MAD homology, MH1
ENSRNOP00000025079 PANTHER PTHR13703 IPR013790 1 468 0.00e-00 Dwarfin
ENSRNOP00000025079 Pfam PF03165 IPR003619 31 131 4.70e-42 MAD homology 1, Dwarfin-type
ENSRNOP00000025079 Pfam PF03166 IPR001132 269 445 3.20e-78 SMAD domain, Dwarfin-type
ENSRNOP00000025079 ProSiteProfiles PS51075 IPR013019 12 136 0.00e-00 MAD homology, MH1
ENSRNOP00000025079 ProSiteProfiles PS51076 IPR001132 274 468 0.00e-00 SMAD domain, Dwarfin-type
ENSRNOP00000025079 SMART SM00523 IPR003619 25 134 1.50e-70 MAD homology 1, Dwarfin-type
ENSRNOP00000025079 SMART SM00524 IPR001132 272 444 5.70e-110 SMAD domain, Dwarfin-type
ENSRNOP00000025079 SUPERFAMILY SSF49879 IPR008984 221 459 0.00e-00 SMAD/FHA domain
ENSRNOP00000025079 SUPERFAMILY SSF56366 IPR013019 13 131 0.00e-00 MAD homology, MH1

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSRNOP00000025079 PF03166 0 MH2 MH2 domain
ENSRNOP00000025079 PF03165 1.69978e-42 MH1 MH1 domain
ENSRNOP00000025079 PF10401 7.3e-07 IRF-3 Interferon-regulatory factor 3

Gene Ontology Annotation
Protein Entry Name Space Description
ENSRNOP00000025079 GO:0001657 biological_process ureteric bud development
ENSRNOP00000025079 GO:0002051 biological_process osteoblast fate commitment
ENSRNOP00000025079 GO:0006351 biological_process transcription, DNA-templated
ENSRNOP00000025079 GO:0006468 biological_process protein phosphorylation
ENSRNOP00000025079 GO:0007179 biological_process transforming growth factor beta receptor signaling pathway
ENSRNOP00000025079 GO:0030509 biological_process BMP signaling pathway
ENSRNOP00000025079 GO:0045669 biological_process positive regulation of osteoblast differentiation
ENSRNOP00000025079 GO:0051216 biological_process cartilage development
ENSRNOP00000025079 GO:0060348 biological_process bone development
ENSRNOP00000025079 GO:0071773 biological_process cellular response to BMP stimulus
ENSRNOP00000025079 GO:1901522 biological_process positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
ENSRNOP00000025079 GO:0005634 cellular_component nucleus
ENSRNOP00000025079 GO:0005667 cellular_component transcription factor complex
ENSRNOP00000025079 GO:0005737 cellular_component cytoplasm
ENSRNOP00000025079 GO:0000979 molecular_function RNA polymerase II core promoter sequence-specific DNA binding
ENSRNOP00000025079 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSRNOP00000025079 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100011974 6087 Hydra magnipapillata 100211577
61853 Nomascus leucogenys 100580616 400682 Amphimedon queenslandica 100639179
143995 Megachile rotundata 100875661 9555 Papio anubis 101017482
7897 Latimeria chalumnae 102346718 59463 Myotis lucifugus 102433398
10090 Mus musculus 17129 9598 Pan troglodytes 450142
9371 Echinops telfairi ENSETEG00000016533 69293 Gasterosteus aculeatus ENSGACG00000017230
9258 Ornithorhynchus anatinus 100089852 7425 Nasonia vitripennis 100116381
7029 Acyrthosiphon pisum 100167170 59729 Taeniopygia guttata 100219645
10224 Saccoglossus kowalevskii 100303484 9986 Oryctolagus cuniculus 100341544
28377 Anolis carolinensis 100556712 30195 Bombus terrestris 100648431
9785 Loxodonta africana 100676711 10141 Cavia porcellus 100717571
132113 Bombus impatiens 100742193 10029 Cricetulus griseus 100768619
7463 Apis florea 100865795 34638 Metaseiulus occidentalis 100907251
9597 Pan paniscus 100992068 39432 Saimiri boliviensis 101036852
9685 Felis catus 101085713 9595 Gorilla gorilla 101137217
9669 Mustela putorius furo 101678475 8083 Xiphophorus maculatus 102217583
6239 Caenorhabditis elegans 176229 7227 Drosophila melanogaster 33529
7955 Danio rerio 445564 9615 Canis familiaris 475456
9544 Macaca mulatta 574340 7668 Strongylocentrotus purpuratus 582943
7070 Tribolium castaneum 659927 9913 Bos taurus 768050
9646 Ailuropoda melanoleuca ENSAMEG00000016645 9358 Choloepus hoffmanni ENSCHOG00000009259
9483 Callithrix jacchus ENSCJAG00000005968 9361 Dasypus novemcinctus ENSDNOG00000006004
10020 Dipodomys ordii ENSDORG00000002526 9796 Equus caballus ENSECAG00000022649
9365 Erinaceus europaeus ENSEEUG00000008384 9606 Homo sapiens ENSG00000113658
9031 Gallus gallus ENSGALG00000017050 8049 Gadus morhua ENSGMOG00000007465
9315 Macropus eugenii ENSMEUG00000005813 9103 Meleagris gallopavo ENSMGAG00000003725
30608 Microcebus murinus ENSMICG00000003343 30611 Otolemur garnettii ENSOGAG00000002742
8128 Oreochromis niloticus ENSONIG00000010000 9978 Ochotona princeps ENSOPRG00000012775
8090 Oryzias latipes ENSORLG00000007377 9813 Procavia capensis ENSPCAG00000009132
7757 Petromyzon marinus ENSPMAG00000009833 13735 Pelodiscus sinensis ENSPSIG00000016396
132908 Pteropus vampyrus ENSPVAG00000014298 42254 Sorex araneus ENSSARG00000009234
9305 Sarcophilus harrisii ENSSHAG00000006387 9823 Sus scrofa ENSSSCG00000025920
37347 Tupaia belangeri ENSTBEG00000011491 99883 Tetraodon nigroviridis ENSTNIG00000017720
31033 Takifugu rubripes ENSTRUG00000014344 9478 Tarsius syrichta ENSTSYG00000000913
9739 Tursiops truncatus ENSTTRG00000008086 30538 Vicugna pacos ENSVPAG00000007328
43179 Ictidomys tridecemlineatus ENSSTOG00000010836