Basic Information
Gene ID ENSTNIG00000010305
Gene Name TCF7L2
Full Name Uncharacterized protein
Organism Tetraodon nigroviridis [99883]

Cross Reference
UniProt H3CY74 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSTNIP00000013209 Gene3D G3DSA:1.10.30.10 IPR009071 192 273 2.60e-28 High mobility group box domain
ENSTNIP00000013209 PANTHER PTHR10373 IPR024940 22 434 0.00e-00 Transcription factor TCF/LEF
ENSTNIP00000013209 PANTHER PTHR10373:SF26 IPR028773 22 434 0.00e-00 Transcription factor 7-like 2
ENSTNIP00000013209 Pfam PF00505 IPR009071 193 260 6.90e-22 High mobility group box domain
ENSTNIP00000013209 Pfam PF08347 IPR013558 14 96 7.60e-36 CTNNB1 binding, N-teminal
ENSTNIP00000013209 ProSiteProfiles PS50118 IPR009071 193 261 0.00e-00 High mobility group box domain
ENSTNIP00000013209 SMART SM00398 IPR009071 192 262 3.90e-25 High mobility group box domain
ENSTNIP00000013209 SUPERFAMILY SSF47095 IPR009071 192 273 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSTNIP00000013209 PF08347 7.6e-36 CTNNB1_binding N-terminal CTNNB1 binding
ENSTNIP00000013209 PF00505 3.2e-22 HMG_box HMG (high mobility group) box
ENSTNIP00000013209 PF09011 1.8e-07 HMG_box_2 HMG-box domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSTNIP00000013209 GO:0006351 biological_process transcription, DNA-templated
ENSTNIP00000013209 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSTNIP00000013209 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSTNIP00000013209 GO:0007275 biological_process multicellular organismal development
ENSTNIP00000013209 GO:0016055 biological_process Wnt signaling pathway
ENSTNIP00000013209 GO:0060070 biological_process canonical Wnt signaling pathway
ENSTNIP00000013209 GO:0005634 cellular_component nucleus
ENSTNIP00000013209 GO:0003677 molecular_function DNA binding
ENSTNIP00000013209 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSTNIP00000013209 GO:0008013 molecular_function beta-catenin binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9597 Pan paniscus 100978424 9555 Papio anubis 101026705
7227 Drosophila melanogaster 43769 28377 Anolis carolinensis ENSACAG00000010433
9646 Ailuropoda melanoleuca ENSAMEG00000015382 7955 Danio rerio ENSDARG00000004415
30608 Microcebus murinus ENSMICG00000007510 9544 Macaca mulatta ENSMMUG00000022799
9978 Ochotona princeps ENSOPRG00000005139 59729 Taeniopygia guttata ENSTGUG00000010805
7029 Acyrthosiphon pisum 100161896 6087 Hydra magnipapillata 100199257
34638 Metaseiulus occidentalis 100905988 39432 Saimiri boliviensis 101037011
9913 Bos taurus ENSBTAG00000021574 9615 Canis familiaris ENSCAFG00000011005
7719 Ciona intestinalis ENSCING00000002003 9483 Callithrix jacchus ENSCJAG00000018987
10141 Cavia porcellus ENSCPOG00000002152 9361 Dasypus novemcinctus ENSDNOG00000012035
10020 Dipodomys ordii ENSDORG00000011398 9796 Equus caballus ENSECAG00000024121
9685 Felis catus ENSFCAG00000018774 8049 Gadus morhua ENSGMOG00000007406
7897 Latimeria chalumnae ENSLACG00000015707 9785 Loxodonta africana ENSLAFG00000018192
9315 Macropus eugenii ENSMEUG00000011191 59463 Myotis lucifugus ENSMLUG00000008783
9669 Mustela putorius furo ENSMPUG00000002032 61853 Nomascus leucogenys ENSNLEG00000015863
9986 Oryctolagus cuniculus ENSOCUG00000008142 30611 Otolemur garnettii ENSOGAG00000014475
8128 Oreochromis niloticus ENSONIG00000016240 8090 Oryzias latipes ENSORLG00000008387
7757 Petromyzon marinus ENSPMAG00000004519 9601 Pongo abelii ENSPPYG00000002661
9598 Pan troglodytes ENSPTRG00000002949 132908 Pteropus vampyrus ENSPVAG00000016688
10116 Rattus norvegicus ENSRNOG00000049232 9823 Sus scrofa ENSSSCG00000010638
43179 Ictidomys tridecemlineatus ENSSTOG00000006847 37347 Tupaia belangeri ENSTBEG00000002995
31033 Takifugu rubripes ENSTRUG00000012549 9478 Tarsius syrichta ENSTSYG00000012796
8364 Xenopus tropicalis ENSXETG00000018735 8083 Xiphophorus maculatus ENSXMAG00000014710
9739 Tursiops truncatus ENSTTRG00000002360