Basic Information | |||
Gene ID | ENSECAG00000024121 | ||
Gene Name | TCF7L2 | ||
Full Name | Uncharacterized protein | ||
Organism | Equus caballus [9796] |
Cross Reference | |||
UniProt | F6X5U4 | UniGene | NULL |
PDB | NULL | OMIM | NULL |
KEGG | NULL | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSECAP00000021617 | Gene3D | G3DSA:1.10.30.10 | IPR009071 | 195 | 277 | 6.10e-29 | High mobility group box domain |
ENSECAP00000021617 | PANTHER | PTHR10373 | IPR024940 | 1 | 468 | 0.00e-00 | Transcription factor TCF/LEF |
ENSECAP00000021617 | PANTHER | PTHR10373:SF26 | IPR028773 | 1 | 468 | 0.00e-00 | Transcription factor 7-like 2 |
ENSECAP00000021617 | Pfam | PF00505 | IPR009071 | 197 | 264 | 7.70e-22 | High mobility group box domain |
ENSECAP00000021617 | Pfam | PF08347 | IPR013558 | 22 | 106 | 2.20e-36 | CTNNB1 binding, N-teminal |
ENSECAP00000021617 | ProSiteProfiles | PS50118 | IPR009071 | 197 | 265 | 0.00e-00 | High mobility group box domain |
ENSECAP00000021617 | SMART | SM00398 | IPR009071 | 196 | 266 | 3.90e-25 | High mobility group box domain |
ENSECAP00000021617 | SUPERFAMILY | SSF47095 | IPR009071 | 196 | 277 | 0.00e-00 | High mobility group box domain |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSECAP00000021617 | PF08347 | 2.2e-36 | CTNNB1_binding | N-terminal CTNNB1 binding |
ENSECAP00000021617 | PF00505 | 3.9e-22 | HMG_box | HMG (high mobility group) box |
ENSECAP00000021617 | PF09011 | 7.7e-08 | HMG_box_2 | HMG-box domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSECAP00000021617 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSECAP00000021617 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
ENSECAP00000021617 | GO:0006357 | biological_process | regulation of transcription from RNA polymerase II promoter |
ENSECAP00000021617 | GO:0007275 | biological_process | multicellular organismal development |
ENSECAP00000021617 | GO:0016055 | biological_process | Wnt signaling pathway |
ENSECAP00000021617 | GO:0060070 | biological_process | canonical Wnt signaling pathway |
ENSECAP00000021617 | GO:0005634 | cellular_component | nucleus |
ENSECAP00000021617 | GO:0003677 | molecular_function | DNA binding |
ENSECAP00000021617 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSECAP00000021617 | GO:0008013 | molecular_function | beta-catenin binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
7425 | Nasonia vitripennis | 100120687 | 9597 | Pan paniscus | 100978424 |
9555 | Papio anubis | 101026705 | 7668 | Strongylocentrotus purpuratus | 373203 |
7227 | Drosophila melanogaster | 43769 | 28377 | Anolis carolinensis | ENSACAG00000010433 |
9646 | Ailuropoda melanoleuca | ENSAMEG00000015382 | 7955 | Danio rerio | ENSDARG00000004415 |
7029 | Acyrthosiphon pisum | 100161896 | 6087 | Hydra magnipapillata | 100199257 |
10224 | Saccoglossus kowalevskii | 100303556 | 400682 | Amphimedon queenslandica | 100641322 |
34638 | Metaseiulus occidentalis | 100905988 | 39432 | Saimiri boliviensis | 101037011 |
13735 | Pelodiscus sinensis | 102459521 | 6239 | Caenorhabditis elegans | 171849 |
10090 | Mus musculus | 21416 | 7070 | Tribolium castaneum | 641465 |
9606 | Homo sapiens | 6934 | 9913 | Bos taurus | ENSBTAG00000021574 |
9615 | Canis familiaris | ENSCAFG00000011005 | 9483 | Callithrix jacchus | ENSCJAG00000018987 |
10141 | Cavia porcellus | ENSCPOG00000002152 | 51511 | Ciona savignyi | ENSCSAVG00000007833 |
9361 | Dasypus novemcinctus | ENSDNOG00000012035 | 10020 | Dipodomys ordii | ENSDORG00000011398 |
9365 | Erinaceus europaeus | ENSEEUG00000007595 | 9685 | Felis catus | ENSFCAG00000018774 |
8049 | Gadus morhua | ENSGMOG00000007406 | 7897 | Latimeria chalumnae | ENSLACG00000015707 |
9785 | Loxodonta africana | ENSLAFG00000018192 | 9315 | Macropus eugenii | ENSMEUG00000011191 |
59463 | Myotis lucifugus | ENSMLUG00000008783 | 9669 | Mustela putorius furo | ENSMPUG00000002032 |
61853 | Nomascus leucogenys | ENSNLEG00000015863 | 9986 | Oryctolagus cuniculus | ENSOCUG00000008142 |
30611 | Otolemur garnettii | ENSOGAG00000014475 | 8128 | Oreochromis niloticus | ENSONIG00000016240 |
7757 | Petromyzon marinus | ENSPMAG00000004519 | 9601 | Pongo abelii | ENSPPYG00000002661 |
9598 | Pan troglodytes | ENSPTRG00000002949 | 132908 | Pteropus vampyrus | ENSPVAG00000016688 |
10116 | Rattus norvegicus | ENSRNOG00000049232 | 9305 | Sarcophilus harrisii | ENSSHAG00000017344 |
9823 | Sus scrofa | ENSSSCG00000010638 | 43179 | Ictidomys tridecemlineatus | ENSSTOG00000006847 |
37347 | Tupaia belangeri | ENSTBEG00000002995 | 31033 | Takifugu rubripes | ENSTRUG00000012549 |
9478 | Tarsius syrichta | ENSTSYG00000012796 | 8364 | Xenopus tropicalis | ENSXETG00000018735 |
8083 | Xiphophorus maculatus | ENSXMAG00000014710 | 9371 | Echinops telfairi | ENSETEG00000018612 |
30608 | Microcebus murinus | ENSMICG00000007510 | 9544 | Macaca mulatta | ENSMMUG00000022799 |
13616 | Monodelphis domestica | ENSMODG00000010133 | 9258 | Ornithorhynchus anatinus | ENSOANG00000001579 |
9978 | Ochotona princeps | ENSOPRG00000005139 | 8090 | Oryzias latipes | ENSORLG00000008387 |
59729 | Taeniopygia guttata | ENSTGUG00000010805 | 99883 | Tetraodon nigroviridis | ENSTNIG00000010305 |
9739 | Tursiops truncatus | ENSTTRG00000002360 | 30538 | Vicugna pacos | ENSVPAG00000008158 |
Paralogs | |||
ENSECAG00000019975 |