>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 35.6 bits (82), Expect = 6e-04 Identities = 21/88 (23%), Positives = 33/88 (37%), Gaps = 18/88 (20%) Query: 217 ARIPAGVLLEGPPGTGKTLLAKAV---AGEAGVPFFS-----ISGSDFVEMFVGV----- 263 + +++ G GTGK L+A+A+ PF + I G Sbjct: 157 MQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAF 216 Query: 264 -GASRVRS-LFEDAKKAAPAIIFIDEID 289 GA + FE A+ +F+DEI Sbjct: 217 TGAQTRSTGRFEQAEGGT---LFLDEIG 241
>SECA#SecA protein signature. Length = 901 Score = 27.5 bits (61), Expect = 0.006 Identities = 10/44 (22%), Positives = 17/44 (38%) Query: 7 SLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCEFLGIKY 50 +SE I SI +D ++ E+ D+ E L + Sbjct: 671 DVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDF 714
>cloacin#Cloacin signature. Length = 551 Score = 25.8 bits (56), Expect = 0.035 Identities = 12/46 (26%), Positives = 28/46 (60%), Gaps = 1/46 (2%) Query: 28 KLQEQRKEEERREEQEFASMIIQGYNHAYERGREAERQEIRKNIRR 73 ++++++ EE RR+++ A+ ++ YER R AE + +++ R Sbjct: 295 QVKQRQDEENRRQQEWDATHPVEAAERNYERAR-AELNQANEDVAR 339
>SECA#SecA protein signature. Length = 901 Score = 24.1 bits (52), Expect = 0.040 Identities = 9/52 (17%), Positives = 21/52 (40%), Gaps = 3/52 (5%) Query: 12 LKRTIEQNEEKIIEYSKPCDARKRRIRALERDLLKKKNKELRKKVEELEDEI 63 L + ++ + + I A+E ++ K ++EL+ K E + Sbjct: 6 LTKVFGSRNDRTLRRMRK---VVNIINAMEPEMEKLSDEELKGKTAEFRARL 54
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 27.9 bits (62), Expect = 0.017 Identities = 7/19 (36%), Positives = 14/19 (73%) Query: 8 EKLGISRATLTRYRKKLGI 26 + LG++R TL + ++LG+ Sbjct: 457 DLLGLNRNTLRKKIRELGV 475
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 27.3 bits (60), Expect = 0.011 Identities = 10/19 (52%), Positives = 11/19 (57%) Query: 16 DEIAKRKGVNRKTIDKYFK 34 EIAK GV R I +FK Sbjct: 35 GEIAKAAGVTRGAIYWHFK 53
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 35.0 bits (80), Expect = 4e-04 Identities = 15/70 (21%), Positives = 26/70 (37%), Gaps = 1/70 (1%) Query: 226 AEIARKEQKEAQEKAKAERLEEIAQSAKKNANANIKAYDAETGEILEQGTITPEPQNNAR 285 E E +EKAK E E+ + K + + K +ET + + +P N + Sbjct: 1098 TETKETATVEKEEKAKVE-TEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIK 1156 Query: 286 EVAKFEPSEP 295 E + Sbjct: 1157 EPQSQTNTTA 1166
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 26.9 bits (59), Expect = 0.025 Identities = 18/65 (27%), Positives = 23/65 (35%) Query: 34 GAITGAAYAALAAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIA 93 G ITG A +AA G + L A+ A G V G V G + F + Sbjct: 233 GHITGGRAAGVAAMQGAVVHLQRATIRRGDAPAGGAVPGGAVPGGAVPGGFGPGGFGPVL 292 Query: 94 SAGIG 98 G Sbjct: 293 DGWYG 297
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 66.6 bits (162), Expect = 2e-13 Identities = 75/489 (15%), Positives = 149/489 (30%), Gaps = 34/489 (6%) Query: 11 LASVAILGAGFVTSQPTFVRAEEAPVASQSKAEKDYDAAVKKSEAAKKHYEEAKKKAKEA 70 ++ +LGAG V + T + A + EK + A K + + Sbjct: 23 AVALTVLGAGLVVN--TNEVSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNN 80 Query: 71 QKKYDEDQKKTEDKAEAVKKADEELQKANLAVQKAYVEYREAKDKASAEKKIEEAKRKQK 130 + D + + TE+ + A +K + + + K D A + Sbjct: 81 KALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADS 140 Query: 131 EANKKFNEEQAKVVPEAKELAATKQKAEKAKKDAEVAKEKYDKAVQEVEVEKNKILEQDA 190 K E+A + +L + A + + +E + ++ + Sbjct: 141 AKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALE 200 Query: 191 ENEKKIDVLQNKVADLEKGIALYQNKVAELNKEIARLQSDLKDAEE--NNVEDYIKE--- 245 K+ LE A + A+L K + + +E Sbjct: 201 GAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEA 260 Query: 246 ---GLEQAIADKKAELATTQQNIDKTQKDLEDAELELEKVLATLDPEGKTQDELDKE-AA 301 LE+A+ I + + E E + + L ++ A Sbjct: 261 RQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDA 320 Query: 302 EDANIEALQNKVADLENKVAELDKEVTRLQSDLKDA---------------EENNVEDYV 346 + L+ + LE + + L+ DL + E+N + + Sbjct: 321 SREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEAS 380 Query: 347 KEGLEKALTDKKVELNNTQKALDTAQKALDTALNELGPDGDEEETPAPAPKPEQPAE--- 403 ++ L + L + +KAL+ A L AL +L + +E + K E A+ Sbjct: 381 RQSLRRDLDASREAKKQVEKALEEANSKLA-ALEKLNKELEESKKLTEKEKAELQAKLEA 439 Query: 404 QPKPAPAPQPAPAPKPEKTDDQQAEEDYARRSEEEYNRLPQQQPPKAEKPAPAPKPEQPV 463 + K A + K +A + ++ + P K + P KP Q Sbjct: 440 EAKALKEKLAKQAEELAKLRAGKASDSQTPDAKPG----NKAVPGKGQAPQAGTKPNQNK 495 Query: 464 PAPKPGWKQ 472 K +Q Sbjct: 496 APMKETKRQ 504
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 24.7 bits (53), Expect = 0.042 Identities = 11/43 (25%), Positives = 22/43 (51%) Query: 31 SELEGRITARQLVEENRPEYNIEYIELLSDKLLDYEKETGAFE 73 S+LE R+ Q + E++ E I+ + L + ++ T +E Sbjct: 102 SQLESRLAVWQAMIESQKEMGIQVSKEFQTALGEAQEATDLYE 144
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 30.7 bits (69), Expect = 0.001 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 7/75 (9%) Query: 48 LAYDGAEVIGFLAVQENLFE-AEVLQIAVKGAYQGQGIASAL------FAQLPTDKEIFL 100 L Y IG + ++ N A + IAV Y+ +G+ +AL +A+ + L Sbjct: 69 LYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLML 128 Query: 101 EVRQSNQRAQAFYKK 115 E + N A FY K Sbjct: 129 ETQDINISACHFYAK 143
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 27.5 bits (61), Expect = 0.023 Identities = 14/56 (25%), Positives = 23/56 (41%), Gaps = 9/56 (16%) Query: 72 EVPAPAEASVATEGN--LVESPLVGVVYLAAGPDKPAFVTVGDSVKKGQTLVIIEA 125 E+ A A + G ++ +V K V G+SV+KG L+ + A Sbjct: 81 EIVATANGKLTHSGRSKEIKPIENSIV-------KEIIVKEGESVRKGDVLLKLTA 129
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 230 bits (587), Expect = 3e-70 Identities = 108/451 (23%), Positives = 205/451 (45%), Gaps = 41/451 (9%) Query: 9 KRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKTGTFAKSDWMDIEKQRGISVT 68 K +++H DAGKTT+TE LLY G I E G+V GT ++D +E+QRGI++ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVD---KGT-TRTDNTLLERQRGITIQ 57 Query: 69 SSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVK 128 + + F ++ +VNI+DTPGH DF + YR+L +D A++++ + G++AQT+ LF ++ Sbjct: 58 TGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALR 117 Query: 129 HRGIPVFTFMNKLDRDGREPLDLLQELEEILGIASYPMNWPIGMGKAFEGLYDLYNQRLE 188 GIP F+NK+D++G + + Q+++E L + + N + Sbjct: 118 KMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIK----------QKVELYPNMCVT 167 Query: 189 LYKGDERFASLEDGDKLFGSNPFYEQVKDDIELLNEAGNEFSEEAILAGELTPVFFGSAL 248 + E++ ++ +G+ + E+ L + L PV+ GSA Sbjct: 168 NFTESEQWDTVIEGN-----DDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAK 222 Query: 249 TNFGVQTFLETFLKFAPEPHGHKKTDGEIVDPYDKDFSGFVFKIQANMDPRHRDRIAFVR 308 N G+ +E + G VFKI+ + R R+A++R Sbjct: 223 NNIGIDNLIEVITNKFYSS----------THRGQSELCGKVFKIE--YSEK-RQRLAYIR 269 Query: 309 IVSGEFERGMSVNLPRTGKGAKLSNVTQFMAESRENVTNAVAGDIIGVYDTG---TYQVG 365 + SG SV + K K++ + + + A +G+I+ + + +G Sbjct: 270 LYSGVLHLRDSVRISEKEK-IKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLG 328 Query: 366 DTLTVGKNKFEFEPLPTFTPEIFMKVSAKNVMKQKSFHKGIEQLVQEG-AVQLYKNYQTS 424 DT + + + PLP + V +++ + ++ ++ Y + T Sbjct: 329 DTKLLPQRERIENPLPL----LQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATH 384 Query: 425 EYMLGAVGQLQFEVFKHRMEGEYNAEVVMSP 455 E +L +G++Q EV ++ +Y+ E+ + Sbjct: 385 EIILSFLGKVQMEVTCALLQEKYHVEIEIKE 415
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.2 bits (65), Expect = 0.044 Identities = 9/35 (25%), Positives = 18/35 (51%) Query: 73 NQSTVAIISLVACFGIAYRLSEGYGTDGPSAGIIA 107 + + ++ + IA R ++G T +AG+IA Sbjct: 277 TKVLGNVGKGISQYIIAQRAAQGLSTSAAAAGLIA 311
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 27.2 bits (60), Expect = 0.003 Identities = 8/22 (36%), Positives = 17/22 (77%) Query: 34 IIDWVLLIVFAIQISYIFWRLS 55 I+ ++L+++F Q++ IFWR+ Sbjct: 17 ILFYLLMLLFCQQLAMIFWRIG 38
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 148 bits (375), Expect = 7e-42 Identities = 72/367 (19%), Positives = 136/367 (37%), Gaps = 66/367 (17%) Query: 2 SKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVV-------SFKNGEIIVGDAAK 54 S + IDLGT N+ + V I+ N PSVV VG AK Sbjct: 10 SNDLSIDLGTANTLIYVKGQ---GIVLN------EPSVVAIRQDRAGSPKSVAAVGHDAK 60 Query: 55 RQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAEDYLGEKVTKAVI 114 + P + +I+ K + +++ ++ + + + ++ Sbjct: 61 QMLGRTPGNIAAIRPM-----KDGVIADFFVTEKMLQHFIKQVHS---NSFMRPSPRVLV 112 Query: 115 TVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDKEEKILVFDLGGGTF 174 VP +R+A +++ + AG ++ EP AAA+ GL + +V D+GGGT Sbjct: 113 CVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGL-PVSEATGSMVVDIGGGTT 171 Query: 175 DVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKENGIDLSTDKMAMQRLKD 234 +V+++ L V + ++GGD FD+ II+++ + G + Sbjct: 172 EVAVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYGSLIG-------------EA 213 Query: 235 AAEKAKKDLS----GVTSTQISLPFITAGEAGPLHLEMTLTRAKFDDL----------TR 280 AE+ K ++ G +I + E P + + + L Sbjct: 214 TAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLN-SNEILEALQEPLTGIVSAVM 272 Query: 281 DLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKSVNPDEV 340 +E+ + +S+ G ++L GG + + + ETG + +P Sbjct: 273 VALEQCPPELASDISERG--------MVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTC 324 Query: 341 VAMGAAI 347 VA G Sbjct: 325 VARGGGK 331
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 75.3 bits (185), Expect = 1e-16 Identities = 60/386 (15%), Positives = 128/386 (33%), Gaps = 58/386 (15%) Query: 10 EFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKEITVTSQGEITPTSVIASIQSTSDNP 69 E + ++ + I S++ EI T+ G++T + I+ +N Sbjct: 47 ELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKP-IENS 105 Query: 70 ILANHLVA-NQVVEKGDLLIKYSETMEESQKTALETQLQRLEKQKEGLGILKQSLE---- 124 I+ +V + V KGD+L+K + E+ ++ L + ++ IL +S+E Sbjct: 106 IVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKL 165 Query: 125 --------KATDLFSSEDEFGY----HNTFMNFTKQSHDIELGISKTNTEVSNQANLTNS 172 S E+ F + Q + EL + K E N Sbjct: 166 PELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINR 225 Query: 173 SSSAIEQEITKVQQQIGEYQELRDTIVNKRARLPTGNPHQSILNRYLIASQEQTQGTAEE 232 + E + ++ ++ L + + N+Y+ A E ++ Sbjct: 226 YENLSRVE----KSRLDDFSSLLHKQAIAKHAV------LEQENKYVEAVNELRVYKSQ- 274 Query: 233 PFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVLRTQFLQTASQQQLTVE 292 + +ES I S K + +++ F + Sbjct: 275 ---------LEQIESEILSAKEE-----------------YQLVTQLFKNEILDKLRQTT 308 Query: 293 NQLTELKVQLDQATQRLGNNTLTAPSKGIVHLNSEFEGKNRIPTGTEIAQIFPVITDTRE 352 + + L ++L + +R + + AP V + T + I P + Sbjct: 309 DNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVP---EDDT 365 Query: 353 VLITYYVSSDYLPLLDKGQTVRLKLE 378 + +T V + + ++ GQ +K+E Sbjct: 366 LEVTALVQNKDIGFINVGQNAIIKVE 391
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 86.4 bits (214), Expect = 2e-19 Identities = 45/139 (32%), Positives = 64/139 (46%), Gaps = 18/139 (12%) Query: 439 IMGHVDHGKTTLLDTLRNSRVATGEAG------------------GITQHIGAYQIVENG 480 ++ HVD GKTTL ++L + A E G GIT G Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 481 KKITFLDTPGHAAFTSMRARGASVTDITILVVAADDGVMPQTIEAINHSKAVNVPIIVAI 540 K+ +DTPGH F + R SV D IL+++A DGV QT + + + +P I I Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 541 NKIDKPGANPERVIGELAE 559 NKID+ G + V ++ E Sbjct: 128 NKIDQNGIDLSTVYQDIKE 146
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.0 bits (70), Expect = 0.021 Identities = 11/73 (15%), Positives = 26/73 (35%), Gaps = 6/73 (8%) Query: 806 YLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQKEKDKQADYQ 865 + +L E + EL ++ +L+ + ++ +AK E + + + Sbjct: 248 AIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEI------LSAKEEYQLVTQLFKNEIL 301 Query: 866 AKYDVTVARIDEM 878 K T I + Sbjct: 302 DKLRQTTDNIGLL 314
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.1 bits (83), Expect = 2e-05 Identities = 27/135 (20%), Positives = 50/135 (37%), Gaps = 10/135 (7%) Query: 11 EVLAKIAKQTFRETFAYDNTEEQLQE-YFEEAYSLKTLSTELGNPDSETYFIMHEEEIAG 69 V ++ + Y TEE+ + YF++ + + + E G Sbjct: 21 VVFGRMIPAFENGVWTY--TEERFSKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIG 78 Query: 70 FLKVNWGSAQTERELEDAFEIQRLYVLQKFQGFGLGKQLFEFALGLATKNSFSWAWLGVW 129 +K+ S L I+ + V + ++ G+G L A+ A +N F L Sbjct: 79 RIKIR--SNWNGYAL-----IEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQ 131 Query: 130 EHNTKAQAFYNRYGF 144 + N A FY ++ F Sbjct: 132 DINISACHFYAKHHF 146
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.8 bits (72), Expect = 0.002 Identities = 20/90 (22%), Positives = 35/90 (38%), Gaps = 20/90 (22%) Query: 30 YRDPYLSNMLNFDPNMP-------AFFLYYEKGELVGLLTV------YADDQDVEVTILV 76 + PY + D ++ A FLYY + +G + + YA +D+ V Sbjct: 42 FSKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVA--- 98 Query: 77 HPDYRRQGIARVLF---TSFEKETAAFSIR 103 DYR++G+ L + KE + Sbjct: 99 -KDYRKKGVGTALLHKAIEWAKENHFCGLM 127 Score = 28.0 bits (62), Expect = 0.028 Identities = 13/52 (25%), Positives = 23/52 (44%) Query: 224 LAISESERGKGYGSYLAKSLVNQLIEQNNKEFQIAVEDSNVGAKRLYEKIGF 275 +A+++ R KG G+ L + E + + +D N+ A Y K F Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.4 bits (79), Expect = 4e-04 Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 4/56 (7%) Query: 218 LHQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKE 273 L+ +L + + I+ +L K A L L+RN+L+ KI + G+ + Sbjct: 428 LYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL----GVSVYR 479
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 31.1 bits (70), Expect = 0.004 Identities = 31/125 (24%), Positives = 47/125 (37%), Gaps = 11/125 (8%) Query: 111 AIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTN---LLTGQFLSVTVR 167 ++Q+W+ F VT + A+IT N +G + T G + Sbjct: 108 SLQSWSDVANLTFTEVTGNKSANITFG--NYTRDA-SGNLDYGTQAYAYYPGNYQGAGSS 164 Query: 168 LNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQEEDVANLRK 227 +Y SN S E T HE+GHA+GL H E + + S+ D Sbjct: 165 WYNYNQSNIRNPGSEEYGRQTFTHEIGHALGLAHPGEYNAGEGDPSY-----NDAVYAED 219 Query: 228 IYETS 232 Y+ S Sbjct: 220 SYQFS 224
>SECBCHAPRONE#Bacterial protein-transport SecB chaperone protein signature. Length = 170 Score = 28.7 bits (64), Expect = 0.004 Identities = 18/82 (21%), Positives = 32/82 (39%), Gaps = 5/82 (6%) Query: 30 DDYSHGAVKLSVSLVDKDAMKK---ISVTVIGYFEI-NIDE-NITDILYVNGTAILYHYL 84 DD + +SV + + V G F I ++E + L +L+ Y Sbjct: 62 DDLYEVCLNISVETTMESSGDVAFICEVKQAGVFTISGLEEMQMAHCLTSQCPNMLFPYA 121 Query: 85 RSIVSIVSAIDSSEAMLLPTIN 106 R +VS + + A+ L +N Sbjct: 122 RELVSSLVNRGTFPALNLSPVN 143
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 28.3 bits (63), Expect = 0.044 Identities = 16/82 (19%), Positives = 29/82 (35%), Gaps = 4/82 (4%) Query: 163 IATASIAFWTKQSGAMIYIFYMFNDFAKYPI--SIYNSLLR-WLISFIVPFAFTAYYPAS 219 +++ + SG + + ++Y S + +VP A+ Sbjct: 856 YDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAA 915 Query: 220 YFLQEK-DVFFNVGGLMLISLV 240 +K DV+F VG L I L Sbjct: 916 TLFNQKNDVYFMVGLLTTIGLS 937
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 93.0 bits (231), Expect = 4e-22 Identities = 50/233 (21%), Positives = 87/233 (37%), Gaps = 57/233 (24%) Query: 209 LKSINAPF-GKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWL 267 ++ I AP GRG+ ++ +DTG D H DLK Sbjct: 26 VEMIQAPAVWNQTRGRGVKVAVLDTGCDADH-----------------PDLKA------- 61 Query: 268 SDKIPHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPN 327 +I N+ + + E + D + HG H+AG +A + N NG+ G+AP Sbjct: 62 --RIIGGRNFTDDDEGDPEIFKDY----NGHGTHVAGTIAATE------NENGVVGVAPE 109 Query: 328 AQIFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL 387 A + K+ + GSG + I +I+ VD++S+S G +A++ Sbjct: 110 ADLLIIKVLNKQGSGQYDW--IIQGIYYAIEQKVDIISMSLGGPEDVPELH---EAVKKA 164 Query: 388 RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVAS 440 + I ++ A GN T + + + I+V + Sbjct: 165 VASQILVMCAAGNEGDGDDR---------------TDELGYPGCYNEVISVGA 202 Score = 59.5 bits (144), Expect = 6e-11 Identities = 36/139 (25%), Positives = 54/139 (38%), Gaps = 32/139 (23%) Query: 660 PDVSAPGKNIKSTLNVINGKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLT 719 D+ APG++I ST+ Y SGTSMATP VA + LI+ ER Sbjct: 219 VDLVAPGEDILSTVP----GGKYATFSGTSMATPHVAGALALIKQLANASFER------- 267 Query: 720 GDDKIDLTSLT-KIALQNTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVAT 778 DLT L P+ + SP+ +G GL+ + ++ Sbjct: 268 -----DLTEPELYAQLIKRTIPLGN------------SPKMEGNGLLYLTAVEE---LSR 307 Query: 779 FKNTDSKGLVNSYGSISLK 797 +T + S S+ +K Sbjct: 308 IFDTQRVAGILSTASLKVK 326
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 40.0 bits (93), Expect = 1e-04 Identities = 46/218 (21%), Positives = 80/218 (36%), Gaps = 16/218 (7%) Query: 2032 QRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYRIQLTK---EKPVSEKTV 2088 + K +E +Q E S L R + S + K+ + K + +SE + Sbjct: 322 REAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASR 381 Query: 2089 AAVQEDLPK----LEFVEKDLA-----YKTVEKKDSTLYLGETRVEQEGKTGKERIFTAI 2139 +++ DL + VEK L +EK + L + E+E + ++ Sbjct: 382 QSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEA 441 Query: 2140 NPDGSKEEKLREVVEAPTDRIVLVG----TKPVAQEAKKPQVSEKADTKPIDSSEASQTN 2195 K K E + KP + + +A TKP + + Sbjct: 442 KALKEKLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKET 501 Query: 2196 KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED 2233 K QLP+TG A+ AA L ++ + V K K+E+ Sbjct: 502 KRQLPSTGETANPFFTAAALTVMATAGVAAVVKRKEEN 539 Score = 37.4 bits (86), Expect = 7e-04 Identities = 32/172 (18%), Positives = 55/172 (31%), Gaps = 14/172 (8%) Query: 7 NRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVYADETLITHTAEKPKEEKMIVEE 66 N R YS+RK G SV + +LG + + + + T K V+E Sbjct: 5 NTNRHYSLRKLKTGTASVAVAL--TVLGAGLVVNTNEVSAVATRSQTDTLEK-----VQE 57 Query: 67 KADKALETKNVVERTEQSEPSSTEAIASEKKEDEAVTPKEEKVSAKLEEKAPRIESQASS 126 +ADK N ++ S A + DE + + +EK + + S Sbjct: 58 RADKFEIENN--TLKLKNSDLSFNNKALKDHNDEL-----TEELSNAKEKLRKNDKSLSE 110 Query: 127 QEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWYFKLNANSKEAIKPDADVST 178 + ++E + E + L A AD+ Sbjct: 111 KASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEK 162
>PF03309#Bvg accessory factor Length = 271 Score = 35.1 bits (81), Expect = 2e-04 Identities = 25/126 (19%), Positives = 45/126 (35%), Gaps = 14/126 (11%) Query: 5 IIGIDLGGTSIKFAILTTAGEIQ---GKWSIKTNILDEGSHIVDDMIESIQHRLDLLGLV 61 ++ ID+ T +++ +G+ +W I+T D++ +I L+G Sbjct: 2 LLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTA----DELALTI---DGLIGDD 54 Query: 62 AADFQGIGMGSPGVVDRENGTVIGAYNLNWKTLQPIKEKIEKDLGIPFFIDNDANVAALG 121 A G S V V W + + + GIP +DN V A Sbjct: 55 AERLTGASGLS--TVPSVLHEVRVMLEQYWPNVPHVLIEPGVRTGIPLLVDNPKEVGA-- 110 Query: 122 ERWMGA 127 +R + Sbjct: 111 DRIVNC 116
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 80.1 bits (197), Expect = 5e-20 Identities = 48/182 (26%), Positives = 87/182 (47%), Gaps = 6/182 (3%) Query: 4 ILITGASGGLAQEMVKLLPND--QLILLGRNKEKLAQLYGNYS----HAELIEIDITDDS 57 ITGA+ G+ + + + L + + + N EKL ++ + HAE D+ D + Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 58 ALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEVNTFALMNLSRHLAAR 117 A++ + + G ID+L+N AG ++D++ F VN+ + N SR ++ Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKY 130 Query: 118 MKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRLELMPYGVYVTTVNPGPI 177 M + G I+ + S + + Y+++K AA+ F+ L LEL Y + V+PG Sbjct: 131 MMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGST 190 Query: 178 RT 179 T Sbjct: 191 ET 192
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 181 bits (461), Expect = 1e-51 Identities = 99/469 (21%), Positives = 193/469 (41%), Gaps = 72/469 (15%) Query: 8 IRNIAIIAHVDHGKTTLVDELLKQSETLD--ARTELAERAMDSNDIEKERGITILAKNTA 65 I NI ++AHVD GKTTL + LL S + + D+ +E++RGITI T+ Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 66 VAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKALEQDLV 125 + T++NI+DTPGH DF EV R + ++DG +L++ A +G QTR + + + Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 126 PIVVVNKIDKPSARPAEVVDEVLELF---------IELGADDDQLDFP--VVYASAING- 173 I +NKID+ + V ++ E +EL + +F + + I G Sbjct: 123 TIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGN 182 Query: 174 ----TSSLSDDPAD------------QEATMAPIF--------------DTIIDHIPAPV 203 +S + ++ P++ + I + + Sbjct: 183 DDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSST 242 Query: 204 DNSDEPLQFQVSLLDYNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFF 263 L +V ++Y++ R+ R++ G + + D V +S + ++T+++ Sbjct: 243 HRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRIS----EKEKIKITEMYTSI 298 Query: 264 GLERREIQEAKAGDLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPF 323 E +I +A +G+++ + E + + + T + + P LQ T Sbjct: 299 NGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPLLQTT-------- 349 Query: 324 AGKEGKWVTSRKVEER------LQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIET 377 V K ++R L +D LR + + +S G++ + + Sbjct: 350 -------VEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCAL 402 Query: 378 MRRE-GYELQVSRPEVIVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLS 425 ++ + E+++ P VI E K E +++ P + S+ S+S Sbjct: 403 LQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVP-PNPFWASIGLSVS 450 Score = 41.0 bits (96), Expect = 1e-05 Identities = 16/77 (20%), Positives = 28/77 (36%), Gaps = 1/77 (1%) Query: 403 EPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPARGLIGYSTEFLS 462 EP+ +I P+EY + ++D N + L +PAR + Y ++ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVD-TQLKNNEVILSGEIPARCIQEYRSDLTF 595 Query: 463 MTRGYGIMNHTFDQYLP 479 T G + Y Sbjct: 596 FTNGRSVCLTELKGYHV 612
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 42.0 bits (98), Expect = 4e-06 Identities = 24/116 (20%), Positives = 53/116 (45%), Gaps = 12/116 (10%) Query: 15 ELKELSEWQKRNQEYLKKKAEEEA--ALAEEKEKERQARMGEESEKSEDKQDQ-ESETDQ 71 E E + + +K E++A A+ +E ++A+ ++ ++ Q SET Sbjct: 1035 ETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSET-- 1092 Query: 72 EDSESAKEESEEKVASSEADKEKEEKEESESKEKEEQDKKLAKKATKEKPAKAKIP 127 +E++ A EKEEK + E+++ +E K ++ + K++ ++ P Sbjct: 1093 -------KETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQP 1141 Score = 40.8 bits (95), Expect = 9e-06 Identities = 24/123 (19%), Positives = 50/123 (40%), Gaps = 8/123 (6%) Query: 2 SKDKKNEDKEILEELKELSEWQKRNQEYLKKKAE-EEAALAEEKEKERQARMGEESEKSE 60 + + +++E+ +E K + + E + +E +E E KE + + ++E Sbjct: 1058 ATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETE 1117 Query: 61 DKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEESESKEKEEQDKKLAKKATKEK 120 Q+ T Q + + E+ + +A+ +E KE + Q A E+ Sbjct: 1118 KTQEVPKVTSQVSPKQEQSETVQP----QAEPARENDPTVNIKEPQSQTN---TTADTEQ 1170 Query: 121 PAK 123 PAK Sbjct: 1171 PAK 1173 Score = 29.3 bits (65), Expect = 0.033 Identities = 10/33 (30%), Positives = 15/33 (45%) Query: 354 ADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEE 386 + E +E E KE ++EE+ K E E Sbjct: 1085 VAQSGSETKETQTTETKETATVEKEEKAKVETE 1117
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 29.3 bits (65), Expect = 0.046 Identities = 24/105 (22%), Positives = 42/105 (40%), Gaps = 14/105 (13%) Query: 475 KNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFTVDRIEDIDAVVAEAVKLNKEGKTVVI 534 K K++D+ +L +FTN KI + Q D ++ I V E G+ Sbjct: 56 KEKFKDSINNLVKTEFTNETLDKIQQTQ-------DLLKKIPKDVLEIYS-ELGGEIYFT 107 Query: 535 DARITQHRPLPVEVLELDPK----LHSEEAIKAFKEKYEAEELVP 575 D + +H+ L + L + K E+ A + +E + P Sbjct: 108 DIDLVEHKEL--QDLSEEEKNSMNSRGEKVPFASRFVFEKKRETP 150
>PF03944#delta endotoxin Length = 633 Score = 30.0 bits (67), Expect = 0.025 Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 8/92 (8%) Query: 332 TFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPMYTFKTMYSYQTPK 391 T+ +LK Y + N I + + R + ++L+F Y F ++ Y + Sbjct: 207 TYRDYLKNYTRDYSNYCINTYQSAFKGLNTR-------LHDMLEFRTYMFLNVFEYVSIW 259 Query: 392 EI-TYKSIVGGKLNNLFVIGKGAYQSESFRSQ 422 + Y+S++ NL+ G G Q++SF SQ Sbjct: 260 SLFKYQSLLVSSGANLYASGSGPQQTQSFTSQ 291
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 30.1 bits (67), Expect = 0.012 Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 3/96 (3%) Query: 58 AEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKNIYLEDHPDTKIHVID 117 AEA+ D+L+A + A + T G L S + A N P + Sbjct: 20 AEAAFEGVRKNTDFLKAADKAFKDVVATKAGDLKAGTKSGESAINTVGLKPPTDAAR--E 77 Query: 118 SLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQ 153 LS+ G++ LL+ KL L+ +S ++ + +Q Sbjct: 78 KLSSEGQLTLLLGKLMTLLGD-VSLSQLESRLAVWQ 112
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.0 bits (132), Expect = 9e-12 Identities = 24/104 (23%), Positives = 47/104 (45%), Gaps = 6/104 (5%) Query: 16 KSNQESNLLTREAIETALLQLLEKKELTKISISELVKRAGVSRAAFYRNYDSKEEILESV 75 + ++ TR+ I L+L ++ ++ S+ E+ K AGV+R A Y ++ K ++ + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 76 FKRTVHNIMEQLHHYDLKTD------LYLVWVHLFREARKEARV 113 ++ + NI E Y K L + +H+ E R Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERR 106
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 117 bits (294), Expect = 1e-36 Identities = 56/146 (38%), Positives = 86/146 (58%), Gaps = 2/146 (1%) Query: 1 MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSRDIKNMNLSKVREED-S 59 MNK + RH IR +IT N+I TQ EL +L ++ VTQAT+SRDIK ++L KV + S Sbjct: 1 MNKGQ-RHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGS 59 Query: 60 AYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGLAQSFGSIIDTLSFPDAI 119 Y L +L+ + DA V + H ++LKT+PG AQ+ G+++D L + + + Sbjct: 60 YKYSLPADQRFNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEEIM 119 Query: 120 ATLCGNDVCLIICEDADTAQKCFEEL 145 T+CG+D LIIC D + +++ Sbjct: 120 GTICGDDTILIICRTHDDTKVVQKKI 145
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 49.4 bits (118), Expect = 7e-09 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 7/101 (6%) Query: 127 GAIPIINENDSVVIDEVKVGDNDTLSAQVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKR 186 G +P+I E+ + E V D D ++A V AD+ ++LTDV+G + R Sbjct: 195 GGVPVILEDGEIKGVEA-VIDKDLAGEKLAEEVNADIFMILTDVNGAALYYGTEKEQWLR 253 Query: 187 LERIETINREIIDMAGGAGSSNGTGGMLTKIKAATIATESG 227 ++E + + + AGS M K+ AA E G Sbjct: 254 EVKVEELRKYYEEGHFKAGS------MGPKVLAAIRFIEWG 288
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 30.2 bits (68), Expect = 0.035 Identities = 21/119 (17%), Positives = 40/119 (33%), Gaps = 7/119 (5%) Query: 347 GEGLKAVTSESLVISLGILPILSF---YFAEFQPWSILLTF--VFSFLFDLTFLPLLS-I 400 + A+ ++V+S +P+ F A ++ +SI + S L L P L Sbjct: 436 SQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCAT 495 Query: 401 LFVLSFLYPVIQLNFIFEWLEGII-RLVSQVTSRPLVFGQPNAWFLILLLISLALVYDL 458 L F W V+ T+ +L++ + +A + L Sbjct: 496 LLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVL 554
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 59.6 bits (144), Expect = 3e-12 Identities = 50/263 (19%), Positives = 102/263 (38%), Gaps = 36/263 (13%) Query: 55 PERVATIAWGNHDVALALGIVPVGLSK-ANYGVSADKGVLPWTEEKIKELNGKANLFDDL 113 P R+ + W ++ LALGIVP G++ NY + + LP + + ++ + Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLP---DSVIDVGLRTE----- 86 Query: 114 DGLNFEAISNSKPDVIL--AGYSGITKEDYDTLSKIAPVAAYK----SKPWQTLWRDMIR 167 N E ++ KP ++ AGY + L++IAP + +P + + Sbjct: 87 --PNLELLTEMKPSFMVWSAGY----GPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTE 140 Query: 168 IDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAADTSKFWIYTS 227 + + L ++ + + E I P + +L T+I D ++ Sbjct: 141 M-ADLLNLQSAAETHLAQYEDFI---RSMKPRFVKRGARPLLLTTLI---DPRHMLVFGP 193 Query: 228 KDPRANYLTDLGLVFPESLKEFESEDSF--AKEISAEEANKINDADVI-ITYGDDKTLEA 284 L + G+ ++ E +F + +S + D DV+ + + K ++A Sbjct: 194 NSLFQEILDEYGIP-----NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDA 248 Query: 285 LQKDPLLGKINAIKNGAVAVIPD 307 L PL + ++ G +P Sbjct: 249 LMATPLWQAMPFVRAGRFQRVPA 271
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 34.5 bits (79), Expect = 0.001 Identities = 19/127 (14%), Positives = 44/127 (34%), Gaps = 6/127 (4%) Query: 390 QEKINMKVDTSEIEKEIDNY-QKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRL 448 + V S +++E D + +LR + + L + + D L ++ Sbjct: 50 GGWVGNGVYVSGVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQM 109 Query: 449 CRMYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVEHRQLISAL 508 + + L S+ D A++ I + + D+ + + + I A Sbjct: 110 QDFFTSLQTLVSNAEDPAARQALIGKSEGLVNQFKT----TDQYLRDQDK-QVNIAIGAS 164 Query: 509 ISEIQVY 515 + +I Y Sbjct: 165 VDQINNY 171
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 37.6 bits (87), Expect = 5e-06 Identities = 24/111 (21%), Positives = 36/111 (32%), Gaps = 10/111 (9%) Query: 20 PQLTDKEAIDEVKKYTNGKNTAIFTEVEGDTIVG-LALCSLRFDYVEGCKYSPVGFLEGI 78 P E D Y + A F + +G + + S Y +E I Sbjct: 45 PYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYA---------LIEDI 95 Query: 79 IVDEEYRLKDIAKNLCTKCEEWAKNKGCKEFASDCTLTNTDSIRFHLNIGF 129 V ++YR K + L K EWAK + N + F+ F Sbjct: 96 AVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 31.1 bits (70), Expect = 0.035 Identities = 19/121 (15%), Positives = 34/121 (28%), Gaps = 8/121 (6%) Query: 428 VVSDKGVPEVQPALSKAVITDKGETEVQPESPDTVVSDKGEPAVQPESPDTVVSDKGEPK 487 S V E+ PA ++ + EP V+PE + + + Sbjct: 34 YTSVHQVIEL-PAPAQPISVTMVAPADLEPPQAVQPPP--EPVVEPEPEPEPIPEPPKEA 90 Query: 488 QV-----APLPEYTGPQASAIVEPEQVAPLPEYTGVQAGAIVEPAVQPALPEAVVSDKGV 542 V P P+ + +P++ E PA + + K V Sbjct: 91 PVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPV 150 Query: 543 P 543 Sbjct: 151 T 151
>cloacin#Cloacin signature. Length = 551 Score = 30.8 bits (69), Expect = 0.028 Identities = 35/154 (22%), Positives = 60/154 (38%), Gaps = 20/154 (12%) Query: 56 EEMREASKAKVKQANEDYNHILQNSPPSLLNRKELRDRRLPHARKRLKIAKKQFREAKVE 115 M + + K ++A D N+ Q + + K D L A + K + + R A+ Sbjct: 387 HRMWQMAGLKAQRAQTDVNN-KQAAFDAAAKEKSDADAALSSAMESRKKKEDKKRSAENN 445 Query: 116 AKEERKESRKERKTNQKFLYGQESKQKSNFFFQGKSLEELKAKKEVKAAKENLKSTKQAY 175 +E+ + RK K YG + + E +K ++K K+ KQ Sbjct: 446 LNDEKNKPRKGFKD-----YGHD-------YHPAPKTENIKGLGDLKPGIP--KTPKQNG 491 Query: 176 KSKKVSRKAKTFLYVLGREGGELASENEDLEGYR 209 K+ GR+ E S++ +LEGYR Sbjct: 492 GGKRKRWTGDK-----GRKIYEWDSQHGELEGYR 520
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 25.9 bits (56), Expect = 0.017 Identities = 6/47 (12%), Positives = 17/47 (36%) Query: 1 MTIIERLEEKVTRQESKVARETEKLAAYKEQLETAMFATFKRRQSIS 47 ++ ++ +T ++ + A + E A + RQ + Sbjct: 197 ISSLQIRMNTLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAA 243
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 66.6 bits (162), Expect = 1e-15 Identities = 32/173 (18%), Positives = 65/173 (37%), Gaps = 16/173 (9%) Query: 1 MARN--RNSHETRKKILEVSKDLFLEKGFDNTSIQDIIDGLGGLTKGVIYHHFESKDEIL 58 MAR + + ETR+ IL+V+ LF ++G +TS+ +I G+T+G IY HF+ K ++ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAA-GVTRGAIYWHFKDKSDLF 59 Query: 59 QSIISENNQEIL-----NYNWRGDTALEKIQNSLMDAFSNLEQQRLVYSA-SIMLRSPRL 112 I + I L ++ L+ + + I+ Sbjct: 60 SEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 113 LGE--QYLNLFSDFLPGIREKVFEGVKDKSIKTEY-----PEELADLIVLTLN 158 +GE + +++ + +K A ++ ++ Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYIS 172
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 1119 bits (2895), Expect = 0.0 Identities = 632/639 (98%), Positives = 636/639 (99%) Query: 1 MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGI 60 MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGI Sbjct: 1 MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGI 60 Query: 61 TSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMG 120 TSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMG Sbjct: 61 TSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMG 120 Query: 121 IPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIE 180 IPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIE Sbjct: 121 IPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIE 180 Query: 181 GNDDLLEKYMSGKSLEALELEQEESKRFQNCSLFPLYHGSAKSNIGIDNLIEVITNKFYS 240 GNDDLLEKYMSGKSLEALELEQEES RF NCSLFP+YHGSAK+NIGIDNLIEVITNKFYS Sbjct: 181 GNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYS 240 Query: 241 STHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSING 300 STHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSING Sbjct: 241 STHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSING 300 Query: 301 ELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREM 360 ELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREM Sbjct: 301 ELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREM 360 Query: 361 LLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIY 420 LLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIY Sbjct: 361 LLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIY 420 Query: 421 MERPLKKAEYTIHIEVPPNPFWASIGLSVAPLPLGSGVQYESSVSLGYLNQSFQNAVMEG 480 MERPLKKAEYTIHIEVPPNPFWASIGLSV+PLPLGSG+QYESSVSLGYLNQSFQNAVMEG Sbjct: 421 MERPLKKAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEG 480 Query: 481 IRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYL 540 IRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYL Sbjct: 481 IRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYL 540 Query: 541 SFKIYAPQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGR 600 SFKIYAPQEYLSRAY DAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGR Sbjct: 541 SFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGR 600 Query: 601 SVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT 639 SVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT Sbjct: 601 SVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT 639
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 39.3 bits (91), Expect = 7e-05 Identities = 34/197 (17%), Positives = 72/197 (36%), Gaps = 18/197 (9%) Query: 526 DTKDRMVDTASGLKEQVKDLPTNARYA-VYQGKSKVKENVRDLTSSISQTKADRASG--R 582 D + KE ++ N + V Q S+ KE T + + + + Sbjct: 1057 DATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVET 1116 Query: 583 KEQQEQRRKT--IAKRRSEMEQVKQKKQPASSVHERPTTRQEQYHDEQTSKQSNIQTSYK 640 ++ QE + T ++ ++ + E V+ + +PA PT ++ QT+ ++ Sbjct: 1117 EKTQEVPKVTSQVSPKQEQSETVQPQAEPARE--NDPTVNIKEP-QSQTNTTAD------ 1167 Query: 641 ESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTTADRTSQRPITKERPSTVQ 700 Q AK+ V+ + GN+V E P +T + + + +P Sbjct: 1168 TEQPAKETSSNVEQPVTESTTVNTGNSVVE----NPENTTPATTQPTVNSESSNKPKNRH 1223 Query: 701 RVPLQNTRSRPPIKTAT 717 R +++ T + Sbjct: 1224 RRSVRSVPHNVEPATTS 1240
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 26.0 bits (57), Expect = 0.041 Identities = 18/63 (28%), Positives = 27/63 (42%), Gaps = 8/63 (12%) Query: 3 PLIQSLTEGQLR-TDIPSFRPGDTVRVHAKVVE-------GNRERIQIFEGVVIARKGAG 54 ++ + +L DI R GD +R+H V GNR++ GVV + A Sbjct: 260 DVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIGNRKKFLCQPGVVGKKIAAQ 319 Query: 55 ISE 57 I E Sbjct: 320 ILE 322
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 28.2 bits (62), Expect = 0.035 Identities = 15/63 (23%), Positives = 35/63 (55%), Gaps = 4/63 (6%) Query: 87 EDLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAE 146 ++LS++ + L M FI+ + K+ + ++D+ +L++ E E++ AE + E Sbjct: 248 DNLSNVARLTMLMAM----FIEIVGKNTEESLQNDLALFNALQEGRQAEMEKKSAEFQEE 303 Query: 147 SKK 149 ++K Sbjct: 304 TRK 306
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 29.7 bits (66), Expect = 0.019 Identities = 15/59 (25%), Positives = 31/59 (52%), Gaps = 1/59 (1%) Query: 151 GISKKTSNSIKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEEN 209 GIS + K + P++ + ++++ + D +L + K +E+ +SI I I+EN Sbjct: 176 GISLDIISKDKSLDPEFLNLIKSLSDDSDSSDLLFSQKFKEKLELNNKSI-DINFIKEN 233
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 47.8 bits (113), Expect = 4e-08 Identities = 78/331 (23%), Positives = 134/331 (40%), Gaps = 65/331 (19%) Query: 25 LDSKINSRDSQKLVIYNWGDYIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTY 84 L S ++S S V+ N+ YI P LL + E+ + + T+ SNE + TY Sbjct: 16 LSSILSSCGSTTFVLANFESYISPLLLERVQEKH--PLTFLTYPSNEKLINGF--ANNTY 71 Query: 85 DIAIPSEYMINKMKDEDLLVPLDYSK-----------------------IEGIENIGPEF 121 +A+ S Y ++++ + DLL P+D+S+ I+ I+ I + Sbjct: 72 SVAVASTYAVSELIERDLLSPIDWSQFNLKKSSSSSDKVNNASDAKDLFIDSIKEISQQT 131 Query: 122 LNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEH---WDDLWKPEYK-------NSIML 171 + + +++PYF L VY + E + W D+ K K N ++ Sbjct: 132 KDSKNNELLHWAVPYFLQNLVFVYRGEKISELEQENVSWTDVIKAIVKHKDRFNDNRLVF 191 Query: 172 FDGAREVLGLG---------------LNSLGYSLNSKDP-QQLEETVDKLYKLTPNIKA- 214 D AR + L + +GY N + Q+L T L + N + Sbjct: 192 IDDARTIFSLANIVNTNNNSADVNPKEDGIGYFTNVYESFQRLGLTKSNLDSIFVNSDSN 251 Query: 215 IVADEM-----KGYMIQNNVAIGVTFSGEASQMLEKNE----NLRYVVPTEASNLWFDNM 265 IV +E+ +G ++ N A+ G+ L + + N ++V + S + D + Sbjct: 252 IVINELASGRRQGGIVYNGDAVYAALGGDLRDELSEEQIPDGNNFHIVQPKISPVALDLL 311 Query: 266 VIPKTVKN-QDSAYAFINFMLKPENALQNAE 295 VI K N Q A+ I F L + A Q E Sbjct: 312 VINKQQSNFQKEAHEII-FDLALDGADQTKE 341
>BCTLIPOCALIN#Bacterial lipocalin signature. Length = 171 Score = 26.1 bits (57), Expect = 0.038 Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 11/85 (12%) Query: 45 KAVAPTTDWKQEN--GMWY-FYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQ-------- 93 ++V P +D++ N G WY D S G QV + N G +N+ Sbjct: 21 ESVKPVSDFELNNYLGKWYEVARLDHSFERGLSQVTAEYRVRNDGGISVLNRGYSEEKGE 80 Query: 94 WFQVGGKWYYVNASGELAVNTSIDG 118 W + GK Y+VN S + + S G Sbjct: 81 WKEAEGKAYFVNGSTDGYLKVSFFG 105
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 29.9 bits (67), Expect = 0.003 Identities = 26/139 (18%), Positives = 41/139 (29%), Gaps = 28/139 (20%) Query: 37 YPNADVIIDDI--ISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFH 94 Y + D+ + + A++ E + + NW + Y + Sbjct: 50 YEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRS------------NW----NGYALIE 93 Query: 95 RIAVAADVQGKGVAQTFLEGLIE---GFDYLDFRSDTHAENKVMQHIFEKLGFKQVG--- 148 IAVA D + KGV L IE + +T N H + K F Sbjct: 94 DIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDT 153 Query: 149 ----KVPVDGERLAYQKLK 163 P E + K Sbjct: 154 MLYSNFPTANEIAIFWYYK 172
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 34.0 bits (78), Expect = 0.001 Identities = 19/94 (20%), Positives = 33/94 (35%), Gaps = 20/94 (21%) Query: 164 RIAVVGG-GYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHNIRLA 222 + V G G+IG +++ G +VV +D LN YYD +L+ + L Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGID----NLNDYYD--------VSLKQARLELL 49 Query: 223 LGQTVKAIEGD----GKVERLITDKESFDVDMVI 252 + + D + L + V Sbjct: 50 AQPGFQFHKIDLADREGMTDLFASGH---FERVF 80
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 31.0 bits (70), Expect = 0.003 Identities = 15/53 (28%), Positives = 22/53 (41%), Gaps = 4/53 (7%) Query: 7 RHVQNILRKQTLKPLSHLKIKSQFKKTRKRFKTSRRF-RKVRLMYQDEAGFGR 58 R + +LR++ L P L + +K T RK+RL D A R Sbjct: 26 RQARQLLRERGLVP---LSVDENRGDQQKSGSTGLSLRRKIRLSTSDLALLTR 75
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 80.7 bits (199), Expect = 2e-18 Identities = 53/153 (34%), Positives = 81/153 (52%), Gaps = 10/153 (6%) Query: 13 VNIGTIGHVDHGKTTLTAAI---TTVLARRLPSSVNQPKDYASIDAAPEERERGITINTA 69 +NIG + HVD GKTTLT ++ + + SV+ K D ER+RGITI T Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITE--LGSVD--KGTTRTDNTLLERQRGITIQTG 59 Query: 70 HVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQV 129 ++ E ID PGH D++ + + +DGAIL++++ DG QTR R++ Sbjct: 60 ITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKM 119 Query: 130 GVKHLIVFMNKVDLVDDEELLELVEMEIRDLLS 162 G+ I F+NK+D + L V +I++ LS Sbjct: 120 GIP-TIFFINKIDQNGID--LSTVYQDIKEKLS 149
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.9 bits (192), Expect = 7e-19 Identities = 31/142 (21%), Positives = 66/142 (46%), Gaps = 3/142 (2%) Query: 3 KILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYH 62 IL+ +DD IR + + LS G++V + + + + LV+ D+ +P N + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 WCQEIRKI-SKVPIMFLSSRDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLL--RRS 119 I+K +P++ +S+++ M + A GA D++ KPFD L+ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 120 YEFGRDESLLEYAGVILNTKSM 141 ++ + ++ + +M Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAM 146
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 352 bits (905), Expect = e-123 Identities = 129/365 (35%), Positives = 184/365 (50%), Gaps = 17/365 (4%) Query: 7 RPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAYGHGAVAVAKAIQDDVDGFCVSN 66 RP +A + L A++QN+ + + +VVKANAYGHG + AI DGF + N Sbjct: 3 RPIQASLDLQALKQNLSIVRQAATHARV-WSVVKANAYGHGIERIWSAI-GATDGFALLN 60 Query: 67 IDEAIELRQAGLSKPILIL-GVSEIEAVALAKEYDFTLTVAGLEWIQALLDKEVDLTGLT 125 ++EAI LR+ G PIL+L G + + + ++ T V ++AL + + L Sbjct: 61 LEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAP-LD 119 Query: 126 VHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVEGIFTHFATADEESDDYFNAQLERFK 185 ++LK++SGM R+GF+ + Q L V + +HFA A+ D + + R + Sbjct: 120 IYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEHP--DGISGAMARIE 177 Query: 186 TILASMKCLPELVHASNSATTLWHVETIFNAVRMGDAMYGLNPSGAVLDL-PYDLIPALT 244 L SNSA TLWH E F+ VR G +YG +PSG D+ L P +T Sbjct: 178 QAAEG---LECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPVMT 234 Query: 245 LESALVHVKTVPAGACMGYGATYQADSEQVIATVPIGYADGWTRDMQN-FSVLVDGQACP 303 L S ++ V+T+ AG +GYG Y A EQ I V GYADG+ R VLVDG Sbjct: 235 LSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTM 294 Query: 304 IVGRVSMDQITIRLPK--PYPLGTKVTLIGSNGDKEITATQVATYRVTINYEVVCLLSDR 361 VG VSMD + + L +GT V L G KEI VA T+ YE++C L+ R Sbjct: 295 TVGTVSMDMLAVDLTPCPQAGIGTPVELWG----KEIKIDDVAAAAGTVGYELMCALALR 350 Query: 362 IPREY 366 +P Sbjct: 351 VPVVT 355
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 26.9 bits (59), Expect = 0.017 Identities = 18/73 (24%), Positives = 31/73 (42%), Gaps = 5/73 (6%) Query: 6 GIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGRRQIEYLAGRWSAKEAFSKAMG 65 GIDIE++ S + A ++ + E + + L +SAKE+ KA Sbjct: 105 GIDIEKIMSQHT----ATELAPSIIDSDERQILQA-SLLPFPLALTLAFSAKESVYKAFS 159 Query: 66 TGISKLGFQDLEV 78 ++ GF +V Sbjct: 160 DRVTLPGFNSAKV 172
>SECA#SecA protein signature. Length = 901 Score = 1055 bits (2729), Expect = 0.0 Identities = 389/904 (43%), Positives = 559/904 (61%), Gaps = 71/904 (7%) Query: 1 MANILKTIIENDKG-EIRRLEKMADKVFKYEDQMAALTDDQLKAKTVEFKERYQNGESLD 59 + +L + + +RR+ K+ + + E +M L+D++LK KT EF+ R + GE L+ Sbjct: 2 LIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLE 61 Query: 60 SLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNAL 119 +L+ EAFAVVRE +KRV G+ + VQ++GG+VL+ + EMRTGEGKTLTAT+P YLNAL Sbjct: 62 NLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNAL 121 Query: 120 SGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLAAKSPMEKKEAYECDITYSTNSE 179 +GKGVHVVTVN+YL++RDA L+ +LGL+VGINL K+EAY DITY TN+E Sbjct: 122 TGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNE 181 Query: 180 IGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGANAVETSQLYHMAD 239 GFDYLRDNM E VQR L+YALVDEVDSILIDEARTPLI+SG + ++Y + Sbjct: 182 YGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSS-EMYKRVN 240 Query: 240 HYVKSLDKD------------DYIIDVQSKTIGLSDSGIDKAESYF-------KLENLYD 280 + L + + +D +S+ + L++ G+ E + E+LY Sbjct: 241 KIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYS 300 Query: 281 IENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGLHQAIEA 340 N+ L H + ALRA+ + D+DY+V ++ E++IVD+ TGRTM+GRR+SDGLHQA+EA Sbjct: 301 PANIMLMHHVTAALRAHALFTRDVDYIV-KDGEVIIVDEHTGRTMQGRRWSDGLHQAVEA 359 Query: 341 KEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIPIPTNRPVQ 400 KEGV IQ+E +T ASIT+QN FR+Y+KL+GMTGT TE EF IY + + +PTNRP+ Sbjct: 360 KEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMI 419 Query: 401 RIDHSDLLYASIEAKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKLVAAGVPHEVL 460 R D DL+Y + K +A++ED+K R KGQPVLVGT+++E S+ +S +L AG+ H VL Sbjct: 420 RKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVL 479 Query: 461 NAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLG----------------------- 497 NAK H EA I+ AG AVTIATNMAGRGTDI LG Sbjct: 480 NAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKA 539 Query: 498 ------EGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFG 551 + V E GGL +IGTERHESRRIDNQLRGRSGRQGD G S+FYLS+ED LM+ F Sbjct: 540 DWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFA 599 Query: 552 SERLKGIFERLNMSE-EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREII 610 S+R+ G+ +L M EAIE +T+ + AQ++VE N+D RKQ+L+YDDV +QR I Sbjct: 600 SDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAI 659 Query: 611 YAQRYDVITADRDLAPEIQAMIKRTIGRVVDGHARAKQDEK---LEAILNFAKYNLLPED 667 Y+QR +++ D++ I ++ + +D + + E+ + + K + + Sbjct: 660 YSQRNELLDVS-DVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDL 718 Query: 668 SIT--MEDLSGLSDKAIKEELFQRALQVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTD 725 I ++ L ++ ++E + ++++VY + + E ++ F+K ++L+ +D+ W + Sbjct: 719 PIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVG-AEMMRHFEKGVMLQTLDSLWKE 777 Query: 726 HIDALDQLRNAVGLRGYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIH----- 780 H+ A+D LR + LRGYAQ +P EY+ E F MF M+ S++++V + K Q+ Sbjct: 778 HLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEV 837 Query: 781 ----EQERPQAEHHISTTATRNIAAHQA---NMPEDLDLSQIGRNELCPCGSGKKFKNCH 833 +Q R +AE + A + ++GRN+ CPCGSGKK+K CH Sbjct: 838 EELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCH 897 Query: 834 GKRQ 837 G+ Q Sbjct: 898 GRLQ 901
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.003 Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 6/81 (7%) Query: 33 LKGDNGSGKTVLLKILAG-YIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSL 91 L+G G GK+ L+ L G D G K+ Y Q AGI+ ++ ++ Sbjct: 601 LEGTGGIGKSTLINTLVGLDFFSD--THFDIGT---GKDSYEQIAGIVAYELSEMTAFRR 655 Query: 92 RENLELLRYFSSKVTEKRIAY 112 + + +FSS+ R AY Sbjct: 656 ADAEAVKAFFSSRKDRYRGAY 676
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.7 bits (98), Expect = 5e-06 Identities = 21/192 (10%), Positives = 56/192 (29%), Gaps = 18/192 (9%) Query: 41 NAEQEATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQE 100 + R Q + L + + + +E R + +F + + + Sbjct: 143 LLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLR-LTSLIKEQFSTWQNQ 201 Query: 101 LKQIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAK----------NLDAREEQL 150 Q E L ++ + E ++ + D + + +E + Sbjct: 202 KYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKY 261 Query: 151 EEVERQKEAELERIG----ALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKM 206 E + ++ + A+ + EI ++R+ + + ++ Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEE---YQLVTQLFKNEILDKLRQTTDNIGLLTLEL 318 Query: 207 AKDILVQAMQRI 218 AK+ Q I Sbjct: 319 AKNEERQQASVI 330
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 28.5 bits (63), Expect = 0.015 Identities = 14/56 (25%), Positives = 24/56 (42%), Gaps = 1/56 (1%) Query: 27 LTHCLGVERAAMELAQRFGVDVEKASLAGLLHDYAKKLSDQEFLVLIDRYQLDFDL 82 ++HC A+ QR G+D+EK + A + D + ++ L F L Sbjct: 88 ISHCATT-ALAVISRQRIGIDIEKIMSQHTATELAPSIIDSDERQILQASLLPFPL 142
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 55.0 bits (132), Expect = 1e-10 Identities = 56/260 (21%), Positives = 93/260 (35%), Gaps = 30/260 (11%) Query: 57 PEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLK-----DLVGTVKNVGSMKEPDLE 111 P +IV + + + ALG IV Y L +V +VG EP+LE Sbjct: 35 PNRIVALEWLPVELLLALG----IVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLE 90 Query: 112 AIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANI--ESLASAFGETG 169 + ++P ++ S + IAP F S + +SL Sbjct: 91 LLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDG----KQPLAMARKSLTEMADLLN 146 Query: 170 TQKAKEE-LAKLDKSIQEVATKNESSDKKALAI--LLNEGKMAAFGAKSRFSFLYQTLKF 226 Q A E LA+ + I+ + + + L + L++ M FG S F + Sbjct: 147 LQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGI 206 Query: 227 KPTDTTFEDSRHGQE-VSFESVKEI-NPDILFVINRTLAIGGDNSSN-DGVLENALIAET 283 P E + G VS + + + D+ L DNS + D ++ L Sbjct: 207 -PNAWQGETNFWGSTAVSIDRLAAYKDVDV-------LCFDHDNSKDMDALMATPLWQAM 258 Query: 284 PAAKNGKIIQLTPDLWYLSG 303 P + G+ Q P +W+ Sbjct: 259 PFVRAGR-FQRVPAVWFYGA 277
>TACYTOLYSIN#Bacterial thiol-activated pore-forming cytolysin signature. Length = 574 Score = 28.4 bits (63), Expect = 0.045 Identities = 26/103 (25%), Positives = 46/103 (44%), Gaps = 9/103 (8%) Query: 223 QSETQFVCDFIGSINKISQEVLKKLQGE-------NKYFKETEGYIRLERVKLE-KTSPQ 274 + T+ + D I S+N EVL K GE + K+ + +I +ER K T+P Sbjct: 106 EDHTEEINDKIYSLNYNELEVLAK-NGETIENFVPKEGVKKADKFIVIERKKKNINTTPV 164 Query: 275 DLSITGVISDIEFNGVLIKYKVDLSNSESIHIIEKNDGLSRHI 317 D+SI ++D + L + ++ ++ K + HI Sbjct: 165 DISIIDSVTDRTYPAALQLANKGFTENKPDAVVTKRNPQKIHI 207
>PF05307#Bundlin Length = 193 Score = 31.3 bits (70), Expect = 0.007 Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 29/152 (19%) Query: 336 KIIEKRYDELLEMIESGDVSSSFDMIRMDMAWLPTFGKK-YFQEIT-SFRQTKSINQNIS 393 KI+ K+Y++ L +IES V + +A T G Y+Q + S + +I++ +S Sbjct: 4 KIMNKKYEKGLSLIESAMV--------LALAATVTAGVMFYYQSASDSNKSQNAISEVMS 55 Query: 394 KSVSREYMYIDQKQYTFPLDVSSQILVYRKDLFEDSFLQRRYFEKTKRKLTVPKSYQEFD 453 + + +YI Q YT ++S IL+ S + Y + K+T P + Sbjct: 56 ATSAINGLYIGQTSYT---GLNSNILL------NTSAIPDNYKDTKNNKITNPFGGE--- 103 Query: 454 ELSEFFTLTENPFSPTLYGHSLALSSSVRAAC 485 L P + T +G+ L L+ +AAC Sbjct: 104 -------LEVGPAANTSFGYYLTLTGLDKAAC 128
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 49.6 bits (118), Expect = 4e-10 Identities = 29/90 (32%), Positives = 42/90 (46%), Gaps = 4/90 (4%) Query: 59 QITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNGLGSLLLEEAIEWAQAS 118 + L +L G + I ++ I D I + K Y G+G+ LL +AIEWA+ + Sbjct: 65 KAAFLYYLENNCIGRIKIRSNWNGYA-LIED--IAVAKDYRKKGVGTALLHKAIEWAKEN 121 Query: 119 GILRRLQLTVQTRNQAAVHLYQKHGFVIEG 148 L L Q N +A H Y KH F+I Sbjct: 122 HFCG-LMLETQDINISACHFYAKHHFIIGA 150
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 116 bits (292), Expect = 2e-31 Identities = 62/225 (27%), Positives = 109/225 (48%), Gaps = 21/225 (9%) Query: 35 GFIWNTIGAPMAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMN 94 G++W I P+ + +K+ + G +G +III+T IVR I+ PL + + KM Sbjct: 331 GWLW-FISQPLFKLLKWIHSFVG-NWGFSIIIITFIVRGIMYPLT-KAQYTSMA---KMR 384 Query: 95 ALKHVLEPHQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPLLLQMPFFSAIY 154 L +P ++E +++ Q + A K ++ GG CFPLL+QMP F A+Y Sbjct: 385 ML----QPKIQAMRERLGDDKQ-RISQEMMALYKAEKVNPLGG--CFPLLIQMPIFLALY 437 Query: 155 FAAQHTEGVAQASYLG----IPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKK 210 + + + QA + + P IL GV + +S V D MQ +K Sbjct: 438 YMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQ----QK 493 Query: 211 MIYMSPLMIVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPK 255 ++ P++ VF L+ P+ + LY++V + I+QQ ++ + + Sbjct: 494 IMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKR 538
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 35.4 bits (81), Expect = 3e-04 Identities = 36/153 (23%), Positives = 65/153 (42%), Gaps = 7/153 (4%) Query: 145 AQSQASKQLATEKESAKNAIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEI- 203 A +A KQ+ E A + + K ++ + L++KEKAEL A++EAE +A +++ Sbjct: 390 ASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLA 449 Query: 204 ENAKTMEDVKEAETIGVQAIVMVTVPKRPVAPNAAPKTTSTPQATAGTMQDVTYQSPAGK 263 + A+ + ++ + Q P A P PQA Q+ + Sbjct: 450 KQAEELAKLRAGKASDSQT------PDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKR 503 Query: 264 QLPNTGSASSAALASLALAAATSGFALLGRKTR 296 QLP+TG ++ + AL + K + Sbjct: 504 QLPSTGETANPFFTAAALTVMATAGVAAVVKRK 536
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 71.0 bits (174), Expect = 8e-17 Identities = 26/122 (21%), Positives = 50/122 (40%), Gaps = 2/122 (1%) Query: 2 KVLVAEDQNMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEKESVDIAILDVEMPVKTG 61 +LVA+D +R + Q L+ V N + + D+ + DV MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 62 LEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVLKERSVADLMQTLHTVLEGR 121 ++L I+ R + V+V++ +A + G Y+ K + +L+ + L Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 122 KE 123 K Sbjct: 123 KR 124
>PF06580#Sensor histidine kinase Length = 349 Score = 34.8 bits (80), Expect = 5e-04 Identities = 28/135 (20%), Positives = 56/135 (41%), Gaps = 19/135 (14%) Query: 242 TLTSELETVKKMLEIAGI----EVETDNQLDTASLTQKLESTASMILLELVTNIIKHAQA 297 +L EL V L++A I ++ +NQ++ A + ++ M++ LV N IKH A Sbjct: 217 SLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQV---PPMLVQTLVENGIKHGIA 273 Query: 298 SK-----VYLKLERTEKELILAVSDDGCGFAFLKGDE----LHTIRDRV---FPFSGEVS 345 + LK + + L V + G + L +R+R+ + ++ Sbjct: 274 QLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIK 333 Query: 346 VISQKHPTEVQVRLP 360 + ++ V +P Sbjct: 334 LSEKQGKVNAMVLIP 348
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.005 Identities = 29/153 (18%), Positives = 53/153 (34%), Gaps = 35/153 (22%) Query: 31 CVALIGPNGAGKTTLLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQ--- 87 V L G G GK+TL++ L+G + I + K Y + V + Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDI-----GTGKDSYEQI---AGIVAYELSE 649 Query: 88 -----KLKVKELIAFFQR---IYPNPLSNQEIDQLLQFV----KQQKEQLAEKLSGGQKR 135 + + + AFF Y D Q V +++ L + G +R Sbjct: 650 MTAFRRADAEAVKAFFSSRKDRYRGAYGRYVQDHPRQVVIWCTTNKRQYLFD--ITGNRR 707 Query: 136 LFSFVLTLIGRPKIVFLDEPTASMDTSTRQRFW 168 + + + GR +V+L + R + + Sbjct: 708 F--WPVLVPGRANLVWLQK--------FRGQLF 730
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 175 bits (445), Expect = 2e-59 Identities = 46/149 (30%), Positives = 80/149 (53%), Gaps = 4/149 (2%) Query: 1 MRKRDRHQLIKKKITEEKLSTQKEIQDRLEAHNVCVTQTTLSRDLREIGLTKVKKNDMVY 60 M K RH I++ IT ++ TQ E+ D L+ VTQ T+SRD++E+ L KV N+ Y Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSY 60 Query: 61 YVLVNETEKIDLVEFLSHHLEG----VARAEFTLVLHTKLGEASVLANIVDVNKDKWILG 116 + ++ + + L L + A +VL T G A + ++D + I+G Sbjct: 61 KYSLPADQRFNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEEIMG 120 Query: 117 TVAGANTLLVICRDQHVAKLMEDRLLDLM 145 T+ G +T+L+ICR K+++ ++L+L+ Sbjct: 121 TICGDDTILIICRTHDDTKVVQKKILELL 149
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.4 bits (240), Expect = 3e-25 Identities = 32/127 (25%), Positives = 60/127 (47%), Gaps = 1/127 (0%) Query: 1 MTKQ-VLLVDDEEHILKLLYYHLSKEGFSTQLVTNGRKALALAETEPFDFILLDIMLPQL 59 MT +L+ DD+ I +L LS+ G+ ++ +N D ++ D+++P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 DGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAVLR 119 + ++ R++ P++++SA++ + A E GA DYL KPF EL+ + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RTKGEQE 126 K Sbjct: 121 EPKRRPS 127
>PF06580#Sensor histidine kinase Length = 349 Score = 43.3 bits (102), Expect = 1e-06 Identities = 38/186 (20%), Positives = 76/186 (40%), Gaps = 33/186 (17%) Query: 261 IYKESLRLEHIVEHLLTLSKA--QQMPIQWTTLSL-AEFVQDLTQSLQPQLKKKDLQLKV 317 I ++ + ++ L L + + + +L+ V Q Q + + LQ + Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDR-LQFEN 244 Query: 318 QVPDDVTLVSDSQLLSQILLNLLSNAIRY----TEQGGKIEVKTQKVNEGIKISVSDTGI 373 Q+ + D Q+ ++ L+ N I++ QGGKI +K K N + + V +TG Sbjct: 245 QINPAI---MDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGS 301 Query: 374 GISQLEQDRIFERFYRVNKGRSRQTGGTGLGLAIVKELSQLLGG---QVTVTSQLGRGSC 430 + ++ TG GL V+E Q+L G Q+ ++ + G+ + Sbjct: 302 LALKNTKE------------------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNA 343 Query: 431 FTIFLP 436 + +P Sbjct: 344 -MVLIP 348
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.2 bits (68), Expect = 0.010 Identities = 30/159 (18%), Positives = 50/159 (31%), Gaps = 9/159 (5%) Query: 78 LPFLAYAILGIFSVQYFFYLCVEYSNATTATILQFISPVFILFYNRLVYQKRASKSAVFY 137 PF A A L + +L E + + F A+ AVF+ Sbjct: 161 APFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFF 220 Query: 138 V--LVAMLGVCLMATKG-DLSQLSMTPLALITGLLSAMGVMFNVILPQPFAKRYGFVPTV 194 + LV + L G D T + + + + ++ P A R G + Sbjct: 221 IMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRAL 280 Query: 195 GWGMILAGLFSNVLSPVYQLSFTLDIWSILICLIIAFFG 233 GMI G + L+F W +++ G Sbjct: 281 MLGMIADG------TGYILLAFATRGWMAFPIMVLLASG 313
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 28.6 bits (64), Expect = 0.046 Identities = 17/94 (18%), Positives = 36/94 (38%), Gaps = 16/94 (17%) Query: 433 DLQVKASSDYDMVFSTIKVETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQ 492 D+ + +D V+ + K M + ++ ++ + + PN + FE Sbjct: 18 DIIERGCRLFDQVYVAVLRNPNK-----QPMFSVQERLEQIAKAIAHLPNAQVDSFE-GL 71 Query: 493 ILNIVKRYGI--ITQ--------ELELRLALKNY 516 +N ++ I + ELEL++A N Sbjct: 72 TVNYARQRQAGAILRGLRVLSDFELELQMANTNK 105
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 552 bits (1425), Expect = 0.0 Identities = 189/408 (46%), Positives = 270/408 (66%), Gaps = 8/408 (1%) Query: 5 PIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIPFLEDAQKEHDAFAQALRDEG 64 PI +FSEIG+LKKV+LHRPG+ELENL P ++ LFDDIP+LE A++EH+ FA L++ Sbjct: 7 PINIFSEIGRLKKVLLHRPGEELENLTPFIMKNFLFDDIPYLEVARQEHEVFASILKNNL 66 Query: 65 IEVLYLEQLAAESLTSP-EIRDQFIEEYLDEANIRDRQTKVAIRELLHGIKDNQELVEKT 123 +E+ Y+E L +E L S + ++FI +++ EA I+ T +++ ++ K Sbjct: 67 VEIEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTINLLKDYFSS-LTIDNMISKM 125 Query: 124 MAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNLYFTRDPFATIGNAVSLNHMFADT 183 ++G+ EL L DLV F IDPMPN+ FTRDPFA+IGN V++N MF Sbjct: 126 ISGVVTEELKNYT---SSLDDLVNGANLFIIDPMPNVLFTRDPFASIGNGVTINKMFTKV 182 Query: 184 RNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIEGGDELILSKDVLAVGISQRTDAASI 243 R RET++ +YIFKYHP+Y V + NR E+ +EGGDEL+L+K +L +GIS+RT+A S+ Sbjct: 183 RQRETIFAEYIFKYHPVYKENVPIWLNRWEEASLEGGDELVLNKGLLVIGISERTEAKSV 242 Query: 244 EKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLHVYSVTY 303 EKL +++FK F +LAF+ NR +MHLDTVFT +DY FT + +Y +TY Sbjct: 243 EKLAISLFKNKTSFDTILAFQIPKNRSYMHLDTVFTQIDYSVFTSFTSDDMYFSIYVLTY 302 Query: 304 ENEK--LKIVEEKGDLAELLAQNLGVEKVHLIRCGGGNIVAAAREQWNDGSNTLTIAPGV 361 + I +EK + ++L+ LG K+ +I+C GG+++ AREQWNDG+N L IAPG Sbjct: 303 NPSSSKIHIKKEKARIKDVLSFYLG-RKIDIIKCAGGDLIHGAREQWNDGANVLAIAPGE 361 Query: 362 VVVYDRNTVTNKILEEYGLRLIKIRGSELVRGRGGPRCMSMPFEREEV 409 ++ Y RN VTNK+ EE G+++ +I SEL RGRGGPRCMSMP RE++ Sbjct: 362 IIAYSRNHVTNKLFEENGIKVHRIPSSELSRGRGGPRCMSMPLIREDI 409
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 407 bits (1048), Expect = e-146 Identities = 140/312 (44%), Positives = 204/312 (65%), Gaps = 5/312 (1%) Query: 4 RKIVVALGGNAIL--SSDPSAKAQQEALVETAKHLVKLIKNGDDLIITHGNGPQVGNLLL 61 +++V+ALGGNA+ S + + + +TA+ + ++I G +++ITHGNGPQVG+LLL Sbjct: 3 KRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLLL 62 Query: 62 QHLASDSEKN-PAFPLDSLVAMTEGSIGFWLKNALQNALLDEGIEKNVASVVTQVIVDKN 120 A + PA P+D AM++G IG+ ++ AL+N L G+EK V +++TQ IVDKN Sbjct: 63 HMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDKN 122 Query: 121 DPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWRKVVASPKPVDIKEIETIRTL 180 DPAF N +KP+GPFY EE AK A + G KED+GRGWR+VV SP P E ETI+ L Sbjct: 123 DPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKL 182 Query: 181 LNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFASQRLAELVDADLFIVLTGVDYVF 240 + G +V+A+GGGG+PV+ E +G + GVEAVIDKD A ++LAE V+AD+F++LT V+ Sbjct: 183 VERGVIVIASGGGGVPVILE-DGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAA 241 Query: 241 VNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPKVEAAIAFVNGRPEGKAVITSLENL 300 + Y ++ L V V +L +Y ++ F GSM PKV AAI F+ +A+I LE Sbjct: 242 LYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIE-WGGERAIIAHLEKA 300 Query: 301 GALIESESGTII 312 +E ++GT + Sbjct: 301 VEALEGKTGTQV 312
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 37.3 bits (86), Expect = 2e-04 Identities = 28/134 (20%), Positives = 50/134 (37%), Gaps = 19/134 (14%) Query: 279 FIPWTDLGVTIF-DDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIGVIY 337 I T+ GVTIF + L GNI+G +G G +L F L + Sbjct: 99 LIGLTERGVTIFAPQLDKLLQKYQKAGNILGGGAENIGDNLGKAGGILSTFQNFLGTALS 158 Query: 338 GLKEDKIISSFMNG----------AADLLSVALIVAIARGIQVIMNDGMITDTILNWGK- 386 +K D++I +G A+ L L+ +A + + + G Sbjct: 159 SMKIDELIKKQKSGGNVSSSELAKASIELINQLVDTVASLNNNV---NSFSQQLNTLGSV 215 Query: 387 ----EGLSGLSSQV 396 + L+G+ +++ Sbjct: 216 LSNTKHLNGVGNKL 229
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.7 bits (74), Expect = 1e-04 Identities = 15/72 (20%), Positives = 32/72 (44%) Query: 12 ERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQDTETSSALISSHYLDEQDLSEKLKS 71 + +SLRK G SV + ++ AG+ + + ++ + Q+ ++K + Sbjct: 5 NTNRHYSLRKLKTGTASVAVALTVLGAGLVVNTNEVSAVATRSQTDTLEKVQERADKFEI 64 Query: 72 ELQWFELENKLL 83 E +L+N L Sbjct: 65 ENNTLKLKNSDL 76
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.7 bits (74), Expect = 9e-04 Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 1/33 (3%) Query: 30 EGENGSGKSTLLQLLAGLETF-DSGLKNCVSKD 61 EG G GKSTL+ L GL+ F D+ KD Sbjct: 602 EGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKD 634
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 31.3 bits (70), Expect = 0.016 Identities = 34/209 (16%), Positives = 77/209 (36%), Gaps = 26/209 (12%) Query: 306 NLFFMTLLALPIYTVIIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESQ 365 N F ++ ++V++FA + +E NA+ DI + +E + Sbjct: 4 NKFIPNKFSIISFSVLLFAIS------SSQAIEVNAMNEHYTESDIKRNHKTEKNKTEKE 57 Query: 366 RYQKIDKEFVDYLKKSFTYSRAESQQKALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLI 425 +++ V + T + + Q LKK+ +L + G + D + Sbjct: 58 KFKDSINNLVKTEFTNETLDKIQQTQDLLKKIPKDVLEIYSELGGEIYFTDID------L 111 Query: 426 TYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTV---EDLSLMKG 482 + L + +N +N + + ++ + E K + +D ++ Sbjct: 112 VEHKELQDLSEEEKNSMNSRGE-------KVPFASRFVFEKKRETPKLIINIKDYAINSE 164 Query: 483 EMTFKQVHYKYGYG--RDVLSDINLTVPQ 509 + K+V+Y+ G G D++S P+ Sbjct: 165 QS--KEVYYEIGKGISLDIISKDKSLDPE 191
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 62.9 bits (153), Expect = 8e-13 Identities = 70/444 (15%), Positives = 149/444 (33%), Gaps = 60/444 (13%) Query: 27 MALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSN---NRILVNHLEENKLVKK 83 M L++ + + + + E+ + + S I+ N I+V +E + V+K Sbjct: 65 MGFLVIAFI-LSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIV---KEGESVRK 120 Query: 84 GDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFR 143 GD+L++ A G +A++ +Q +L+ + +Q Y S N PE Sbjct: 121 GDVLLKLT--ALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQN 178 Query: 144 DYISQVGSLRASTSQQNETIASQNAAASQT----QAEIGNLISQTEAKIRDYQTVKSAIE 199 +V L + +Q T +Q +AE ++++ + KS ++ Sbjct: 179 VSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLD 238 Query: 200 TGASLAGQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQ 259 +SL + + + + ++ +S L + + Sbjct: 239 DFSSLLHKQAI----------AKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSA--- 285 Query: 260 QAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVL 319 + ++ ++ L + + LL ++ + E I A + Sbjct: 286 KEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNE-------ERQQASVIRAPVSVKV 338 Query: 320 HLNPETSDSSMVAEGALLAQLYPS---LEREGKAKLTAYLSSKDVARIKVGDSVR----- 371 ++ +V L + P LE + +KD+ I VG + Sbjct: 339 QQLKVHTEGGVVTTAETLMVIVPEDDTLEVTAL------VQNKDIGFINVGQNAIIKVEA 392 Query: 372 --YTTTHDAGNQLFLDSTITSIDATATKTEK-GNFFKIEAEIN----LTSEQAEKLRYGV 424 YT L + +I+ A + ++ G F + I T + L G+ Sbjct: 393 FPYTRYGY------LVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGM 446 Query: 425 EGRLQMITGKKSYLRYYLDQFLNK 448 ++ TG +S + Y L Sbjct: 447 AVTAEIKTGMRSVISYLLSPLEES 470
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 28.4 bits (63), Expect = 0.033 Identities = 18/74 (24%), Positives = 30/74 (40%), Gaps = 4/74 (5%) Query: 122 KNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINE----LLKVWFAEIGLKLIDFKL 177 K D L I+ V F + +D + + I + WF + + + ++ Sbjct: 868 KEDKLSLADIDFRDVAFKREGNDLIMYKGEGNVLSIGHKNGITFRNWFEKESGDISNHEI 927 Query: 178 EFGFDKDGKIILAD 191 E FDK G+II D Sbjct: 928 EQIFDKSGRIITPD 941
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 31.1 bits (70), Expect = 0.036 Identities = 29/127 (22%), Positives = 41/127 (32%), Gaps = 35/127 (27%) Query: 1100 ANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVSHGEGKFV--VTAE 1157 S + NDA A VE+RI L+ + G G VTA+ Sbjct: 220 TQSNTSGRDLNDAQLKFANDVESRIQRRIEAILSPIV-----------GNGNVHAQVTAQ 268 Query: 1158 EFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQIIGKMGHSERYEDG 1217 +DF K + Y+PNG SK ++ SE+ G Sbjct: 269 ---------------LDFANKEQTEEHYSPNGDA-------SKATLRSRQLNISEQVGAG 306 Query: 1218 LFQNIPG 1224 +PG Sbjct: 307 YPGGVPG 313
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 30.0 bits (67), Expect = 0.015 Identities = 11/33 (33%), Positives = 15/33 (45%) Query: 193 YSLVRRVFADYTGEEVLPELEGKKLKEVLLEPT 225 YS R+ F DY E E E K L+ + + Sbjct: 93 YSQTRQYFYDYQIESNPREKEYKNLRNAISKNK 125
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 29.8 bits (67), Expect = 0.006 Identities = 9/35 (25%), Positives = 14/35 (40%), Gaps = 1/35 (2%) Query: 105 YLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDT 139 +P WN G+ GV + +D+G D Sbjct: 21 EIPRGVEMIQAPAVWNQTRGR-GVKVAVLDTGCDA 54
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 31.0 bits (70), Expect = 0.010 Identities = 14/90 (15%), Positives = 35/90 (38%), Gaps = 6/90 (6%) Query: 146 DGLALGKGVVVAETVEQAVEAAHEMLLDNKFGDSGA--RVVIEEFLEGEEF----SLFAF 199 D L L KG++V E+ + E L + F + + ++ + + + ++F Sbjct: 220 DELVLNKGLLVIGISERTEAKSVEKLAISLFKNKTSFDTILAFQIPKNRSYMHLDTVFTQ 279 Query: 200 VNGDKFYIMPTAQDHKRAYDGDKGPNTGGM 229 ++ F + + Y P++ + Sbjct: 280 IDYSVFTSFTSDDMYFSIYVLTYNPSSSKI 309
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 42.0 bits (98), Expect = 3e-06 Identities = 35/156 (22%), Positives = 55/156 (35%), Gaps = 15/156 (9%) Query: 16 SKNKPEEQAQEVADKAEETIADLDTPIGKNTQVEEEVSQAEVELESQQEEKIETPEGG-- 73 S K Q EVA ET + T K T E+ +A+VE E QE T + Sbjct: 1074 SNVKANTQTNEVAQSGSETK-ETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPK 1132 Query: 74 EARTEIEEKKASNSTEEEPDLSKETEKVTIAEESQEALPQQKATTKEPLLISKSLESPYI 133 + ++E + +A + E +P +E Q T + S ++E P Sbjct: 1133 QEQSETVQPQAEPARENDP--------TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVT 1184 Query: 134 PDQAPKSRDKWKEQVLDFWSWLVEAIKSPTSKLETS 169 + + E + A PT E+S Sbjct: 1185 ESTTVNTGNSVVENPEN----TTPATTQPTVNSESS 1216 Score = 37.0 bits (85), Expect = 1e-04 Identities = 26/127 (20%), Positives = 55/127 (43%), Gaps = 4/127 (3%) Query: 18 NKPEEQAQEVADKAEETIADLDTPIGKNTQVEEEVSQAEVELESQQEEKIETPEGGEART 77 E +++ + E+ D +N +V +E +++ V+ +Q E ++ T Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKE-AKSNVKANTQTNEVAQS-GSETKET 1095 Query: 78 EIEEKKASNSTEEEPDLSKETEKVTIAEE--SQEALPQQKATTKEPLLISKSLESPYIPD 135 + E K + + E+E ETEK + SQ + Q+++ T +P P + Sbjct: 1096 QTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNI 1155 Query: 136 QAPKSRD 142 + P+S+ Sbjct: 1156 KEPQSQT 1162
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 27.5 bits (61), Expect = 0.041 Identities = 14/70 (20%), Positives = 25/70 (35%) Query: 105 FAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGASSLV 164 F+I A + + L + G + S +LI + GA++ Sbjct: 62 FSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFP 121 Query: 165 LLGISYVARF 174 L + VAR+ Sbjct: 122 ALVMVVVARY 131
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 44.0 bits (104), Expect = 6e-07 Identities = 63/361 (17%), Positives = 119/361 (32%), Gaps = 19/361 (5%) Query: 6 LFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSLGVLTSLPLLMFTLFSPFSTQL 65 + + +G+ L P VLP +L ++ +V + G+L +L LM +P L Sbjct: 10 ILSTVALDAVGIGLIMP--VLPGLLRDLVHSNDV-TAHYGILLALYALMQFACAPVLGAL 66 Query: 66 AQKIGLEHLFTYSLFFLTIGSLIRLI--NLPLLYLGTLMVGASVAVINVLLPSLI----- 118 + + G + SL + I L +LY+G ++ G + A V + I Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG-AYIADITD 125 Query: 119 QANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGLILLLTLLCLATFLVWLP- 177 + + GF++ + M L + A + L FL+ Sbjct: 126 GDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESH 185 Query: 178 --NHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFYTAMTWLPTMSIHAGLSS 235 R R A + + +F Q + A W+ + Sbjct: 186 KGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDA 245 Query: 236 HEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVSLAGVVGISMLFFPINNFIY 295 G+ + ++ I + R LML + +A G +L F Sbjct: 246 TTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGM--IADGTGYILLAFATR---G 300 Query: 296 WLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGLSQTGGYILAAFGPTLFGYSFD 355 W+A +++ A+ + + + E+ QL G + + GP LF + Sbjct: 301 WMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYA 360 Query: 356 L 356 Sbjct: 361 A 361
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 82.1 bits (203), Expect = 4e-19 Identities = 54/306 (17%), Positives = 99/306 (32%), Gaps = 60/306 (19%) Query: 294 TILVTGAGGSIGSEICRQ----------VSRFNPERIVLLGHGENSIYLVYHELIRKFQG 343 LVTGA G IG + ++ + N V L EL+ + Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQAR-------LELLAQ--- 51 Query: 344 IDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFKNNIRGTYNVAK 403 + D+ D + + +F V+ + V NP +N+ G N+ + Sbjct: 52 PGFQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILE 111 Query: 404 AVDEAKVSKMVMIST---------------DKAVNPPNVMGATKRVAELIVTGFNQRSQS 448 K+ ++ S+ D +P ++ ATK+ EL+ ++ Sbjct: 112 GCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGL 171 Query: 449 TYCAVRFGNVLGSRGS---VIPVFERQIAEGGPVTV-TDFRMTRYFMTI----------- 493 +RF V G G + F + + EG + V +M R F I Sbjct: 172 PATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQ 231 Query: 494 -------PEASRLVIHAGAYAKDGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEV 546 + + A V+ + PV++ D + L E + Sbjct: 232 DVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQ---ALEDALGIEAKKNML 288 Query: 547 GIRPGE 552 ++PG+ Sbjct: 289 PLQPGD 294
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.6 bits (71), Expect = 0.003 Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 4/41 (9%) Query: 28 FEPG-KF-YSII--GESGAGKSTLLSLLAGLDSPVEGSILF 64 EPG KF YS++ G G GKSTL++ L GLD + Sbjct: 589 MEPGCKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDI 629
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.3 bits (211), Expect = 2e-21 Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 1/104 (0%) Query: 2 KILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYEVALVLLDIQMPKLNGLE 61 IL+ +D+ IR ++ L+ GY+ ++ ++ + LV+ D+ MP N + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLAEIRKT-SQVPVLMLTAFQDEEYKMSAFASLADGYLEKPFSL 104 +L I+K +PVL+++A + A A YL KPF L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDL 108
>PF06580#Sensor histidine kinase Length = 349 Score = 32.5 bits (74), Expect = 0.003 Identities = 29/166 (17%), Positives = 61/166 (36%), Gaps = 30/166 (18%) Query: 288 ILSLSSV--QELRDDRETIDLLQMTKNLVKDYALLAKER-------ELQIDNSLTHQQAY 338 + SLS + LR L +V Y LA + E QI+ ++ Q Sbjct: 197 LTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQ-- 254 Query: 339 LNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSFSDNASR 398 V +++ L+ N IKH + + G++ + +++ + + S Sbjct: 255 ----VPPMLVQTLVENGIKHGIAQ-----LPQGGKILL---KGTKDNGTVTLEVENTGSL 302 Query: 399 KVK----GSGMGLFVVKSLLEH---EKLAYRFEMEENRLTFFIAFP 437 +K +G GL V+ L+ + + ++ ++ + P Sbjct: 303 ALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.3 bits (71), Expect = 0.007 Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 2/72 (2%) Query: 96 GNLAIYIFASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSF 155 GN A + A +V +L YE+W I V L LG+ + + + + F Sbjct: 869 GNQAPALVAISFVVVFLCLAALYESWS-IPVSVMLVVPLGIVGVLLAATLFNQKND-VYF 926 Query: 156 LVGSYALLGLLA 167 +VG +GL A Sbjct: 927 MVGLLTTIGLSA 938
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.016 Identities = 14/23 (60%), Positives = 16/23 (69%) Query: 31 VVVLLGPSGSGKSTLIRTINGLE 53 VVL G G GKSTLI T+ GL+ Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLD 620
>SECA#SecA protein signature. Length = 901 Score = 31.8 bits (72), Expect = 0.006 Identities = 34/216 (15%), Positives = 80/216 (37%), Gaps = 46/216 (21%) Query: 140 KWSGRTIEMDDTIQPRIQAKIY---KENFEEDKLSKSTRQAIRTARNKGLEIQYGGLELL 196 W + I Q +++++ + K+ E D ++ R+AI + RN+ L++ + Sbjct: 621 PWVTKAIA---NAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETIN 677 Query: 197 DSFSELMKKTEKRKEIHLRNEAYYK-----KLLDNFKEDSYITLTSLDVSKRLRELEEQL 251 ++ K T + ++ ++ + L + K D + L + + EL E+ Sbjct: 678 SIREDVFKAT---IDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEET 734 Query: 252 EKNRVVA---------------EKFNDATRS-------SKVQENIKEKERLKEEIDFLQG 289 + R++A E + S +E++ + L++ I Sbjct: 735 LRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGI----H 790 Query: 290 YMNMGKSNIPLAATLSLEFGNTSVNLYAGMDDDFKR 325 + + P E+ S +++A M + K Sbjct: 791 LRGYAQKD-PK-----QEYKRESFSMFAAMLESLKY 820
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.9 bits (67), Expect = 0.024 Identities = 25/114 (21%), Positives = 44/114 (38%), Gaps = 14/114 (12%) Query: 176 LVKKAETFGIRLKKLKREELSIFKNITKET------SER-----REYSDKSLEYYEHFYD 224 LV+ A+ GI ++ ++ +I K + +ER DK L+ Y+ + Sbjct: 67 LVRTADELGIEVQYDEKNGTAITKQVFGTAEKLIGLTERGVTIFAPQLDKLLQKYQKAGN 126 Query: 225 SFGEQAEFLIASLNFSEYMSKLQGEQSKLEEILDKLRLD-LSKNPHSEKKQNQL 277 G AE + N + L Q+ L L +++D L K S + Sbjct: 127 ILGGGAENIGD--NLGKAGGILSTFQNFLGTALSSMKIDELIKKQKSGGNVSSS 178
>adhesinb#Adhesin B signature. Length = 310 Score = 27.1 bits (60), Expect = 0.047 Identities = 13/33 (39%), Positives = 17/33 (51%), Gaps = 1/33 (3%) Query: 1 MKKWQTCVLGAGSLLCLTACS-GKSVTSEHQTK 32 MKK + VL + + L ACS KS T +K Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSSK 33
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 95.3 bits (237), Expect = 1e-24 Identities = 35/129 (27%), Positives = 65/129 (50%), Gaps = 6/129 (4%) Query: 4 TILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWELIQKQVPDIILTDINMPHLN 63 TIL+ +D+ +R L + ++ A YD+ N W I D+++TD+ MP N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVR---ITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 64 GIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDDYLLKPFSRQDIEEMLGKIKQK 123 L +++ P + ++ ++ + F A+ A + G DYL KPF D+ E++G I + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF---DLTELIGIIGRA 118 Query: 124 LDKEEKEEQ 132 L + ++ Sbjct: 119 LAEPKRRPS 127
>PF06580#Sensor histidine kinase Length = 349 Score = 199 bits (508), Expect = 3e-61 Identities = 58/202 (28%), Positives = 100/202 (49%), Gaps = 9/202 (4%) Query: 357 QEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFHDSQRVVQVTKSLATYFRLAL-NQG 415 ++ QL AL +QINPHF++N L+ I + D + ++ SL+ R +L Sbjct: 154 MASMAQEAQLMALKAQINPHFMFNALNNIRALIL-EDPTKAREMLTSLSELMRYSLRYSN 212 Query: 416 KDLICLSDEINHVRQYLFIQKQRYGDKLEYEINENVAFDNLVLPKLVLQPLVENALYHGI 475 + L+DE+ V YL + ++ D+L++E N A ++ +P +++Q LVEN + HGI Sbjct: 213 ARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGI 272 Query: 476 KEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQDAGDSSQSQLKRGGVGLQNVDQRLKLHF 535 + G I L K + + + +E+ G S G GLQNV +RL++ + Sbjct: 273 AQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKES------TGTGLQNVRERLQMLY 326 Query: 536 GANYQMKIDSRPQKGTKVEIYI 557 G Q+K+ + K + I Sbjct: 327 GTEAQIKLSEKQGKVN-AMVLI 347
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 54.3 bits (130), Expect = 5e-09 Identities = 39/272 (14%), Positives = 89/272 (32%), Gaps = 29/272 (10%) Query: 178 VETPQSTTNQEQARTENQVVETE------------EAPKEEAPRTEESPK---------- 215 + + T E ++ E++ VE E KE + + + Sbjct: 1032 TPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSE 1091 Query: 216 -EEPKSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAE 274 +E ++ T+ K E+ K ++ + V +V +V K E+ V+P+++P+ + Sbjct: 1092 TKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDP 1151 Query: 275 ESKVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDE---QPAE 331 ++ P Q QP + + + ++ E P+ QP Sbjct: 1152 TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTV 1211 Query: 332 APEIKVEEPVESKEETKTAKGTQEEGKEGQAPVQEVNPEYKVTTGTVEKSTE---SELDF 388 E + + ++ E V +T T ++ Sbjct: 1212 NSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFV 1271 Query: 389 TTEVVPDDTKYVDEEVVERQGSKGVQVTKTTY 420 V ++++ + + +G V V+ T+ Sbjct: 1272 ALNVGKAVSQHISQLEMNNEGQYNVWVSNTSM 1303 Score = 42.7 bits (100), Expect = 2e-05 Identities = 45/250 (18%), Positives = 78/250 (31%), Gaps = 26/250 (10%) Query: 280 PPVEQAKVPEQPVQPT-----QAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPE 334 P VE+ T QA+ PS P + + E P E E Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAE 1042 Query: 335 IKVEEPVESKEETKTAKGTQEEGKEGQAPVQEVNPEYKVTTGTVEKSTESELDFTTEVVP 394 SK+E+KT + +++ E A +EV E K ++ E Sbjct: 1043 -------NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEV---------- 1085 Query: 395 DDTKYVDEEVVERQGSKGVQVTKTTYETVEVVETDKVLSTTTEVKTPVVPKVVKKGTKPV 454 + +E + + V K VE +T +V T++V PK + T Sbjct: 1086 AQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVS----PKQEQSETVQP 1141 Query: 455 EGTAVETREEVIPFATKEQEDGTLKRGTRQVAQEGVNGKKQITETYKTIRGEKTNEAPTV 514 + + + + + T + + N ++ +TE+ G E P Sbjct: 1142 QAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPEN 1201 Query: 515 EETVLQAPQD 524 P Sbjct: 1202 TTPATTQPTV 1211 Score = 42.0 bits (98), Expect = 3e-05 Identities = 57/253 (22%), Positives = 88/253 (34%), Gaps = 28/253 (11%) Query: 264 PESQPSDKPAEESKVEPPVEQAKVPEQPVQP----TQAEQPSTPKESSQQENP---KEDR 316 P + +D P+ S E E A+V E PV P T +E T E+S+QE+ K ++ Sbjct: 1000 PNNIQADVPSVPSNNE---EIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQ 1056 Query: 317 GAEETPKQEDEQPAEA-----PEIKVEEPVESKEETKTAKGTQEEGKEGQAPVQEVNPEY 371 A ET Q E EA + E +S ETK + T+ + + E + Sbjct: 1057 DATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETK----ETATVEKEEKA 1112 Query: 372 KVTTGTVEKSTESELDFTTEVVPDDTKYVDEEVVERQGSKGVQVT----KTTYETVEVVE 427 KV T + T+ T++V P + + + + Sbjct: 1113 KVET----EKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADT 1168 Query: 428 TDKVLSTTTEVKTPVVP-KVVKKGTKPVEGTAVETREEVIPFATKEQEDGTLKRGTRQVA 486 T++ V+ PV V G VE T P E + R R V Sbjct: 1169 EQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVR 1228 Query: 487 QEGVNGKKQITET 499 N + T + Sbjct: 1229 SVPHNVEPATTSS 1241 Score = 32.7 bits (74), Expect = 0.018 Identities = 22/99 (22%), Positives = 36/99 (36%), Gaps = 12/99 (12%) Query: 160 DTVLEETSAKPGEVTVVEVETPQSTTNQEQ-----ARTENQVVE---TEEAPKEEAPRTE 211 +TV + V ++ PQS TN A+ + VE TE Sbjct: 1137 ETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVV 1196 Query: 212 ESPKEEPKSEVKPTDDT----LPKVEEGKEDSAEPAPVE 246 E+P+ + +PT ++ PK + + P VE Sbjct: 1197 ENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVE 1235
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 96.7 bits (240), Expect = 2e-26 Identities = 66/252 (26%), Positives = 106/252 (42%), Gaps = 24/252 (9%) Query: 3 KRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLL-----EGDFHFLQRDLTLDL-- 55 K ITG + GIG A AR +G + VD + L D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 56 -----EPIFDWCPQV---DVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVELTRYY 107 E ++ D+L N AGVL + + ++ + F +N +R Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLR-PGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 108 LTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGIQVFGIAP 167 M++ + G I+ + S + + AY SSK A FTK L L+ AE I+ ++P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 168 GAVKTAMT--------AADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAMQ 219 G+ +T M A+ G + + P+K+ +P +IA+ LFL SG+A + Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 220 GQILTIDGGWSL 231 L +DGG +L Sbjct: 248 MHNLCVDGGATL 259
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 76.0 bits (187), Expect = 1e-17 Identities = 49/224 (21%), Positives = 91/224 (40%), Gaps = 30/224 (13%) Query: 24 VGMIRGEYLLRELNQNIILASCQEFVKDYLDTICSFYLGKEVWYRFSEL-TNTEANCLVG 82 +G+ R E+L + +Q L + +E + Y + + GK V R ++ + E + L Sbjct: 293 IGLYRTEFLYMDRDQ---LPTEEEQFEAYKEVVQRMD-GKPVVIRTLDIGGDKELSYL-- 346 Query: 83 TREFFDEGHPLFGYRGTRRLLACLDEF--QAEAHVVTEVYQTNPNLSLIFPFVNDADQLK 140 + E +P G+R R L D F Q A + Y NL ++FP + ++L+ Sbjct: 347 --QLPKELNPFLGFRAIRLCLEKQDIFRTQLRALLRASTY---GNLKVMFPMIATLEELR 401 Query: 141 QAITVLRQYGFTG-----------KVGTMIELPSAYFDLDRILETGISKIVVGMNDLTSF 189 QA ++++ +VG M+E+PS + + + +G NDL + Sbjct: 402 QAKAIMQEEKDKLLSEGVDVSDSIEVGIMVEIPSTAVAANLFAKE-VDFFSIGTNDLIQY 460 Query: 190 VFATMRN----SQWHDMESPIMLDMLRDMQDKARKNKINFAVAG 229 A R S + P +L ++ + A + G Sbjct: 461 TMAADRMNERVSYLYQPYHPAILRLVDMVIKAAHSEGKWVGMCG 504
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.3 bits (211), Expect = 2e-21 Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 1/118 (0%) Query: 2 IKILLVEDDLGLSNSVFDFLDD-FADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGF 60 IL+ +DD + + L DV + +G DL++ D+++P++N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 61 QVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKR 118 +L +++ PVL+M+A+ + E GA DYL KPF L EL I L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>PF06580#Sensor histidine kinase Length = 349 Score = 34.8 bits (80), Expect = 5e-04 Identities = 13/76 (17%), Positives = 30/76 (39%), Gaps = 9/76 (11%) Query: 314 FRFENRIHRTIVTDQLLLKQL---MTI--LFDNAVKY----TEEDGEIDFLISATDRNLY 364 +FE+R+ + ++ M + L +N +K+ + G+I + + + Sbjct: 234 IQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVT 293 Query: 365 LLVSDNGIGISTEDKK 380 L V + G K+ Sbjct: 294 LEVENTGSLALKNTKE 309
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 32.1 bits (73), Expect = 0.003 Identities = 32/150 (21%), Positives = 53/150 (35%), Gaps = 21/150 (14%) Query: 1 MKKIFLTLL----TVSLLGGASTAVAQDFTIAAKHA------IAVEANTGKILYEKDATQ 50 M+ I L ++ T+ L AS + ++ I ++ +G+ L A + Sbjct: 1 MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADE 60 Query: 51 PVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME----ARNY 106 + S K++ V ++ G L + L S P+ A Sbjct: 61 RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYR--QQDLVDYS-----PVSEKHLADGM 113 Query: 107 TVEELLEATLVSSANSAAIALAEKIAGSEK 136 TV EL A + S NSAA L + G Sbjct: 114 TVGELCAAAITMSDNSAANLLLATVGGPAG 143
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 35.6 bits (82), Expect = 6e-05 Identities = 22/98 (22%), Positives = 44/98 (44%), Gaps = 12/98 (12%) Query: 1 MLKTERKQLILEELNQHHVVSLEKLVSLLE-----TSESTVRRDLDELEAENKLRRVHG- 54 M K +R I E + + + + ++LV +L+ +++TV RD+ EL +V Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKELHL----VKVPTN 56 Query: 55 GAELPHSLQEEETIQ--EKSVKNLQEKKLLAQKAASLI 90 +SL ++ K ++L + + A+ LI Sbjct: 57 NGSYKYSLPADQRFNPLSKLKRSLMDAFVKIDSASHLI 94
>LCRVANTIGEN#Low calcium response V antigen signature. Length = 326 Score = 29.7 bits (66), Expect = 0.016 Identities = 21/78 (26%), Positives = 32/78 (41%) Query: 80 FVQVAEDTRINVKIKADQETEINGTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNL 139 VQ+ +D I++ IK D + V + +E LK IL+ ED ++ G L Sbjct: 35 LVQLVKDKNIDISIKYDPRKDSEVFANRVITDDIELLKKILAYFLPEDAILKGGHYDNQL 94 Query: 140 GNVIYKDLISLTRQTGAQ 157 N I + L Q Sbjct: 95 QNGIKRVKEFLESSPNTQ 112
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 34.0 bits (78), Expect = 0.002 Identities = 12/70 (17%), Positives = 28/70 (40%), Gaps = 1/70 (1%) Query: 11 LIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGLLIYLFFFKWIRKQEGLL-SGFFTIFA 69 + + K+ I ++ +I+ + +L L G+ I +Q ++ + F + + Sbjct: 140 FLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQILRQLMVICTVGFVVIS 199 Query: 70 GLLLIFEAYL 79 FE Y Sbjct: 200 IADYAFEYYQ 209
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.4 bits (68), Expect = 0.002 Identities = 24/102 (23%), Positives = 38/102 (37%), Gaps = 3/102 (2%) Query: 45 ALDNNKNTKKEPTTSQTTTIVKEIQKESPQENTSP---NKENKTSQEKTQQEETPKSSVK 101 A + N K T++ E ++ E KE K E + +E PK + + Sbjct: 1069 AKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQ 1128 Query: 102 EEKKEEQKTSTQDSSTPAPTPSKPATENEKQSNTPTSENKTN 143 K+EQ + Q + PA E QS T T+ + Sbjct: 1129 VSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQ 1170
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 30.1 bits (67), Expect = 0.027 Identities = 24/123 (19%), Positives = 48/123 (39%), Gaps = 27/123 (21%) Query: 601 LLAHSALESNWGRSKIAKDK----NNFFGI----------TAYDTTPYLSA--------- 637 +LA +ALES WG+ +I ++ N FG+ T TT Y + Sbjct: 174 ILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKF 233 Query: 638 KTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGM----NVEYASDPYWGEKIASVMMK 693 + + + + + N T + G + YA+DP++ K+ +++ + Sbjct: 234 RVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQ 293 Query: 694 INE 696 + Sbjct: 294 MKS 296
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 685 bits (1769), Expect = 0.0 Identities = 197/574 (34%), Positives = 321/574 (55%), Gaps = 31/574 (5%) Query: 1 MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQSHRLLLSAHPVFGRIQ 60 M+ DG FL+ I++EL++ ++NG+I K+NQP + E++L IR R S +LL+S+ + RI Sbjct: 1 MALDGIFLYSIIDELKNTIINGKIDKVNQPEKDEIILNIRKGRLSFKLLISSSSNYPRIH 60 Query: 61 LTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEITVSNKNEIGDHIQATLII 120 LT T NP + F MVLRKY+ A I I Q+ DRIV I + +E+G + +LII Sbjct: 61 LTDLTKPNPIKAPMFCMVLRKYISNAKIVDIHQINQDRIVVIDFESTDELGFNSIYSLII 120 Query: 121 EIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGSTYIAPPSTESLNPFTIKDEK 180 EIMG+HSN+ L+ K + I++ IKH+ N+YR++ PG Y+ PP + LNPF + Sbjct: 121 EIMGRHSNMTLIRKRDNIIMDSIKHITPDINTYRSIYPGIEYVYPPKSPKLNPFDFSYDM 180 Query: 181 LFEILQ--TQELTAKNLQSLFQGLGRDTANELERILVSEKL---------------SAFR 223 + + + +L +F G+ + ++E+ L + + F+ Sbjct: 181 IENFTKENSLQLNDNIFSKIFTGVSKTLSSEICFRLKNNSIDLSLSNLKEIVEVCKDLFK 240 Query: 224 NFFNQETKPCLTETSFSPVPFA--------NQVGEPFANLSDLLDTYYKDKAERDRVKQQ 275 + + + + S V F + + + S LL+ +Y K + DR+K + Sbjct: 241 EIQSNKFEFNCYTKNNSFVGFYCLNLMSKEDYKKIQYDSSSKLLENFYYAKDKSDRLKSK 300 Query: 276 ASELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILDN 335 +S+L + V N + + K K L ++ + F+ GELLT ++ + + L N Sbjct: 301 SSDLQKIVMNNINRCTKKDKILNNTLKKCEDKDIFKLYGELLTANIYALKKGLSHIELAN 360 Query: 336 YYTNQ--PIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVETV 393 YY+ + I LD+ TP+QN Q Y+K+Y KLK++ + + + + + + YL SV T Sbjct: 361 YYSENYDTVKITLDENKTPSQNVQSYYKKYNKLKKSEEAANEQLLQNEEELNYLYSVLTN 420 Query: 394 LNQA-GLEEIAEIREELIQTGFIRRRQ--REKIQKRKKLEQYLASDGKTIIYVGRNNLQN 450 +N A +EI EI++ELI+TG+I+ ++ + K K K +++ DG IYVG+NN+QN Sbjct: 421 INNADNYDEIEEIKKELIETGYIKFKKIYKSKKSKTSKPMHFISKDGID-IYVGKNNIQN 479 Query: 451 EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQVD 510 + LT K A K ++WFH K+IPGSHV++ +D ++ +AA LAAY+S+ + S+ V VD Sbjct: 480 DYLTLKFANKHDIWFHTKNIPGSHVIVKNIMDIPESTLLEAANLAAYYSKSQNSSNVPVD 539 Query: 511 MIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKK 544 EVK + KP G KPG V Y+ +T+ VTP + Sbjct: 540 YTEVKNVKKPNGAKPGMVIYSTNQTIYVTPTNPN 573
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 36.4 bits (84), Expect = 1e-04 Identities = 43/207 (20%), Positives = 80/207 (38%), Gaps = 34/207 (16%) Query: 3 FKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTTDKEQIVFIDTPG 62 + SG + LG + G + N ++ ++ I T+ + + ++ IDTPG Sbjct: 25 YNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS-------FQWENTKVNIIDTPG 77 Query: 63 IHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGDDMIIERLKAAKVPVILVVNK 122 H DF+ E Y +L +D + ++ A + ++ L+ +P I +NK Sbjct: 78 -HM------DFLAE-VYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFINK 129 Query: 123 IDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSRLVDILSENLDEGFQYFPSDQIT 182 ID+ + ID D KE + + V ++ N E Q+ D + Sbjct: 130 IDQ-------NGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQW---DTVI 179 Query: 183 DHPERFLVSEMVREKVL---HLTREEI 206 + + L EK + L E+ Sbjct: 180 EGNDDLL------EKYMSGKSLEALEL 200
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 106 bits (267), Expect = 1e-27 Identities = 69/357 (19%), Positives = 142/357 (39%), Gaps = 9/357 (2%) Query: 10 LRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQVAFYAGLAISVSAISAALFSPIWGI 69 L + L I L++P +P + +L V S V + G+ +++ A+ +P+ G Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDL-VHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 70 LADKYGRKPMMIRAGLAMTITMGGLAFVPNIYWLIFLRLLNGVFAGFVPNATALIASQVP 129 L+D++GR+P+++ + + +A P ++ L R++ G+ A A IA Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITD 125 Query: 130 KEKSGSALGTLSTGVVAGTLTGPFIGGFIAELFGIRTVFLLVGSFLFLAAILTICFIKED 189 ++ G +S G + GP +GG + F F + L + + E Sbjct: 126 GDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 190 FQPVAKEKAIPTKELFTSVKYPYL---LLNLFLTSFVIQFSAQSIGPILALYVRDLGQTE 246 + + S ++ + L F++Q Q + ++ D + Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWD 244 Query: 247 NLLFVSGLIVSSMG-FSSIMSAGVMGKLGDKVGNHRLLVVAQFYSVIIYLLCANASSPLQ 305 G+ +++ G S+ A + G + ++G R L++ Y+L A A+ Sbjct: 245 ATTI--GISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWM 302 Query: 306 LGLYRFLFGLGTGALIPGVNALLSKMTPKAGISRVFAFNQVFFYLGGVVGPMAGSAV 362 L G G +P + A+LS+ + ++ L +VGP+ +A+ Sbjct: 303 AFPIMVLLASG-GIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAI 358 Score = 56.8 bits (137), Expect = 5e-11 Identities = 44/178 (24%), Positives = 76/178 (42%), Gaps = 2/178 (1%) Query: 214 LLNLFLTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSIMSAGVMGKL 273 L+ + T + I P+L +RDL + ++ G++++ A V+G L Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 274 GDKVGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTP 333 D+ G +L+V+ + + Y + A A L + R + G+ TGA A ++ +T Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI-TGATGAVAGAYIADITD 125 Query: 334 KAGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFR 391 +R F F F G V GP+ G + G F HA F+A + + L Sbjct: 126 GDERARHFGFMSACFGFGMVAGPVLG-GLMGGFSPHAPFFAAAALNGLNFLTGCFLLP 182
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 1e-05 Identities = 20/76 (26%), Positives = 35/76 (46%), Gaps = 3/76 (3%) Query: 48 IAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP--DFY 105 I + + IE + V ++ R +G+G+ LL +A AK + C + T FY Sbjct: 82 IRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFY 141 Query: 106 QKHGYKEVFSLQDYLY 121 KH + + ++ LY Sbjct: 142 AKHHFI-IGAVDTMLY 156
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 30.7 bits (69), Expect = 0.013 Identities = 30/129 (23%), Positives = 42/129 (32%), Gaps = 8/129 (6%) Query: 50 LMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDV--PSSPAEES 107 ++A L T + + P P P +PAD E P P + V P E Sbjct: 28 VVAGLLYTSVHQVIELPA-PAQPISVTMVAPADL---EPPQAVQPPPEPVVEPEPEPEPI 83 Query: 108 GSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDIIRDTSRR 167 P PV +K + P V K+ + P E R TS Sbjct: 84 PEPPKEAPVVIEKPKP--KPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSST 141 Query: 168 SRREGAKPV 176 + +KPV Sbjct: 142 ATAATSKPV 150
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 39.9 bits (93), Expect = 1e-06 Identities = 33/136 (24%), Positives = 61/136 (44%), Gaps = 22/136 (16%) Query: 25 SFPAEKQQLSHILEESIRKCADTFLLARDENQLLGYI-LSSPQSDNPQYLKVHSLVIESD 83 + + +S++ EE L EN +G I + S + Y + + + D Sbjct: 49 QYEDDDMDVSYVEEE-----GKAAFLYYLENNCIGRIKIRSNWNG---YALIEDIAVAKD 100 Query: 84 HQRQGLGTLLLAALKEVAVELDYKGIRLESPDELLS---YFEMNGF----VDEEATLLY- 135 ++++G+GT LL E A E + G+ LE+ D +S ++ + F VD T+LY Sbjct: 101 YRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVD---TMLYS 157 Query: 136 --ATSQGYSMIWFNPF 149 T+ ++ W+ F Sbjct: 158 NFPTANEIAIFWYYKF 173
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 31.7 bits (72), Expect = 0.006 Identities = 16/55 (29%), Positives = 24/55 (43%), Gaps = 9/55 (16%) Query: 306 IVNDTVI--IDDFA-----HHPTEIIATLDAARQKYPSKEIVAVFQPHTFTRTIA 353 ++ D V+ I D H+P I + A Q P +VAVF F +T+ Sbjct: 103 LITDDVLKAITDCIELAPLHNPANIEG-IKACTQIMPDVPMVAVFDT-AFHQTMP 155
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 450 bits (1159), Expect = e-163 Identities = 308/309 (99%), Positives = 309/309 (100%) Query: 1 MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIV 60 MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIV Sbjct: 1 MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIV 60 Query: 61 PIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVSD 120 PIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVSD Sbjct: 61 PIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVSD 120 Query: 121 GVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKL 180 GVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKL Sbjct: 121 GVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKL 180 Query: 181 DKLDKESKNKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEEGTPEQIKTLV 240 DKLDKESK+KFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEEGTPEQIKTLV Sbjct: 181 DKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEEGTPEQIKTLV 240 Query: 241 EKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTDSIAEQGKEGDSYYSMMKYNL 300 EKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTDSIAEQGKEGDSYYSMMKYNL Sbjct: 241 EKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTDSIAEQGKEGDSYYSMMKYNL 300 Query: 301 DKIAEGLAK 309 DKIAEGLAK Sbjct: 301 DKIAEGLAK 309
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 50.6 bits (121), Expect = 2e-08 Identities = 24/137 (17%), Positives = 57/137 (41%), Gaps = 13/137 (9%) Query: 198 SQFDQKVYNIARLKYQDLAGLNAFSSAYEEKSKQHQEDLE--QTLSDNGKV-RLQLLKKE 254 +Q QK N+ + + + + A + YE S+ + L+ +L + + +L++E Sbjct: 200 NQKYQKELNLDKKR-AERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQE 258 Query: 255 GQESLDKGQETLDKAQTNLQEGKRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQ 314 + +A L+ K +L ++ I + + + L Q+ + + +L Q Sbjct: 259 NK---------YVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTD 309 Query: 315 ELGKEEDKLKQAEQNLA 331 +G +L + E+ Sbjct: 310 NIGLLTLELAKNEERQQ 326 Score = 41.4 bits (97), Expect = 1e-05 Identities = 25/161 (15%), Positives = 55/161 (34%), Gaps = 18/161 (11%) Query: 208 ARLKYQDLAGLNAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLD 267 + +L L E + E+ L+ K + + + + + LD Sbjct: 155 ILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQ----KYQKELNLD 210 Query: 268 KAQTNLQEGKRRLAAAQARIQAQESQLALF---------PQVQREQASAQLTQAKQELGK 318 K + R+ + + ++S+L F + + + +A EL Sbjct: 211 KKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRV 270 Query: 319 EEDKLKQAEQNLAQEKEKLEKHQQ-----VLDDLAEPRYQV 354 + +L+Q E + KE+ + Q +LD L + + Sbjct: 271 YKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNI 311 Score = 30.6 bits (69), Expect = 0.036 Identities = 20/119 (16%), Positives = 43/119 (36%), Gaps = 21/119 (17%) Query: 249 QLLKKEGQESLDKGQE--TLDKAQTNLQEGKRRLAAAQARIQAQESQLAL---------- 296 +++ KEG+ S+ KG L K + + QAR++ Q+ Sbjct: 109 EIIVKEGE-SVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPE 167 Query: 297 --------FPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEKEKLEKHQQVLDDL 347 F V E+ + K++ +++ Q E NL +++ + ++ Sbjct: 168 LKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRY 226
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.006 Identities = 12/27 (44%), Positives = 18/27 (66%), Gaps = 1/27 (3%) Query: 32 KGELVIIL-GASGAGKSTVLNLLGGMD 57 K + ++L G G GKST++N L G+D Sbjct: 594 KFDYSVVLEGTGGIGKSTLINTLVGLD 620
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.3 bits (65), Expect = 0.022 Identities = 38/180 (21%), Positives = 63/180 (35%), Gaps = 19/180 (10%) Query: 74 AQDTAERVKQAAHERSNNIIHQAEQDAQRLLEEAKYKANEILRQATDNAK--KVAVETEE 131 + AE KQ + N EQDA + + A E N + +VA E Sbjct: 1037 TETVAENSKQESKTVEKN-----EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSE 1091 Query: 132 LKNKSRVFHQRLKSTIESQLAIVESSDWEDILRPTATYLQTSDEAFKEVVSEVLGEPIPA 191 K + + + + A VE+ +++ + T+ Q S + + + EP Sbjct: 1092 TKETQTTETKETATVEKEEKAKVETEKTQEVPKVTS---QVSPKQEQSETVQPQAEPAR- 1147 Query: 192 PIEEEPIDMTRQFSQAEMEELQARIEVADKELSEFEAQIKQEVETPTPV-VSPQVEEEPL 250 E +P ++ A E KE S + ++Q V T V V E P Sbjct: 1148 --ENDPTVNIKE--PQSQTNTTADTEQPAKETS---SNVEQPVTESTTVNTGNSVVENPE 1200
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 48.1 bits (114), Expect = 5e-08 Identities = 31/178 (17%), Positives = 58/178 (32%), Gaps = 11/178 (6%) Query: 251 QDTPKEPGNKKPSA-PKPGMQPSPQPEVKPQLEKPKPEVKPQLEKPKPEVKPQPEKPKPE 309 D P P N + A P P P + + E Q K + + + + Sbjct: 1005 ADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQ 1064 Query: 310 VKPQPEKPKPEVKPQPE-------KPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQPEKPK 362 + ++ K VK + + + E + + EK K E + E PK Sbjct: 1065 NREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPK 1124 Query: 363 PEVKPQLEKPKPDNSKPQADDKKPSTTNNLSKDKQPSNQASTNEKATNKPKKSLPSTG 420 + ++ + + +PQA+ + + K+ Q T +P K S Sbjct: 1125 VTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTN---TTADTEQPAKETSSNV 1179 Score = 45.1 bits (106), Expect = 5e-07 Identities = 44/255 (17%), Positives = 85/255 (33%), Gaps = 9/255 (3%) Query: 166 NQEKEKAKLAVATYMSKILDDIQKHHLQKEKHRQIVALIKELDELKKQALSEIDNVNTKV 225 N E EK V T ++IQ + + +A + E + + T Sbjct: 982 NPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVA 1041 Query: 226 EIENTVHKIFA--DMDAVVTKFKKGLTQDTPKEPGNKKPSAPKPGMQPSPQPEVKPQLEK 283 E K + DA T + K + S E + K Sbjct: 1042 ENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETK 1101 Query: 284 PKPEVKPQLEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQLEKPKPEV 343 V+ + EK K E + E PK + P++ + E +P E P + +P+ Sbjct: 1102 ETATVEKE-EKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ- 1159 Query: 344 KPQPEKPKPEVKPQPEKPKPEVKPQLEKPKPDNSKPQADDKKPSTTNNLSKDKQPSNQAS 403 + + ++ V+ + + N+ + +TT QP+ + Sbjct: 1160 --SQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPA---TTQPTVNSE 1214 Query: 404 TNEKATNKPKKSLPS 418 ++ K N+ ++S+ S Sbjct: 1215 SSNKPKNRHRRSVRS 1229 Score = 45.1 bits (106), Expect = 5e-07 Identities = 49/299 (16%), Positives = 88/299 (29%), Gaps = 36/299 (12%) Query: 132 PQPEKPEHQKPTTPAPDTKPSPQPEGKKPSVPDINQEKEKAKLAVATYMSKILDDIQKHH 191 P+ EK TT PSVP N+E + A + Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADV---PSVPSNNEEIARVDEAPVPPPAPATPSETTET 1039 Query: 192 LQKEKHRQIVALIKELDELKKQALSEIDNVNTKVEIENTVHKIFADMDAVVTKFKKGLTQ 251 + + ++ + E +Q +E N +V E + V + Sbjct: 1040 VAENSKQE-----SKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGS---- 1090 Query: 252 DTPKEPGNKKPSAPKPGMQPSPQPEVKPQLEKPKPEVKPQLEKPKPEVKPQPEKPKPEVK 311 E + + K + + EK K E + E PK + P++ + E Sbjct: 1091 ----ETKETQTTETK-------ETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSET- 1138 Query: 312 PQPEKPKPEVKPQPEKPKPEVKPQLEKPKPEVKPQPEK------PKPEVKPQPEKPKPEV 365 +P+ E + + +PQ + QP K +P + V Sbjct: 1139 ---VQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSV 1195 Query: 366 KPQLEKPKPDNSKPQAD---DKKPSTTNNLSKDKQPSNQASTNEKATNKPKKSLPSTGS 421 E P ++P + KP + S P N + ++ +L S Sbjct: 1196 VENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTS 1254 Score = 43.1 bits (101), Expect = 2e-06 Identities = 43/281 (15%), Positives = 80/281 (28%), Gaps = 29/281 (10%) Query: 130 ETPQPEKPEHQKPTTPAPDTKPSPQPEGKKPSVPDINQEKEKAKLAVATYMSKILDDIQK 189 P E AP P+P + N ++E + + + Sbjct: 1007 VPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNE--QDATETTAQ 1064 Query: 190 HHLQKEKHRQIVALIKELDELKKQALSEIDNVNTKVEIENTVHKIFADMDAVVTKFKKGL 249 + ++ + V + +E+ + + T+ + TV K + K Sbjct: 1065 NREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEK---------EEKAKVE 1115 Query: 250 TQDTPKEPGNKKPSAPKPGMQPSPQPEVKPQLEKPKPEVKPQLEKPKPEVKPQPEKPKPE 309 T+ T + P +PK + QP+ +P E P V + + + E+P E Sbjct: 1116 TEKTQEVPKVTSQVSPKQEQSETVQPQAEPARE-NDPTVNIKEPQSQTNTTADTEQPAKE 1174 Query: 310 VKPQPEKPKPEVKPQPEKPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQL 369 E+P E P+ P +P V + + Sbjct: 1175 TSSNVEQPVTESTTVNTGNSVVENPENT--------TPATTQPTVNSESSNKPKNRHRRS 1226 Query: 370 EKPKPDNSKPQADDKKPSTTNNLSKDKQPSNQASTNEKATN 410 + P N +P S D+ TN Sbjct: 1227 VRSVPHNVEPATTS---------SNDRSTVALCDLTSTNTN 1258
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 73.9 bits (181), Expect = 1e-15 Identities = 47/242 (19%), Positives = 84/242 (34%), Gaps = 24/242 (9%) Query: 258 GEPATPDKKENDAKSSDSSVGEETLPSPSLKPEKKVAEAEKKVEEAKKKAE--------D 309 P+ P E A+ ++ V +PS E VAE K+ + +K E Sbjct: 1006 DVPSVPSNNEEIARVDEAPVPPPAPATPSETTET-VAENSKQESKTVEKNEQDATETTAQ 1064 Query: 310 QKEEDRRNYPTNTYKTLELEIAESDVEVKKAELELVKEEAKEPQNEEKVKQAKAEVESKQ 369 +E + T E+A+S E K+ + E KE EK ++AK E E Q Sbjct: 1065 NREVAKEAKSNVKANTQTNEVAQSGSETKETQ----TTETKETATVEKEEKAKVETEKTQ 1120 Query: 370 AEATRLEKIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAPAP 429 ++ ++++E + + ++PQ + P E + Sbjct: 1121 EVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVE 1180 Query: 430 KPEN----------PAEQPKAEKPADQQAEEDYA-RRSEEEYNRLTQQQPPKTEKPAQPS 478 +P E P+ PA Q + + +R + + P +PA S Sbjct: 1181 QPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTS 1240 Query: 479 TP 480 + Sbjct: 1241 SN 1242 Score = 59.3 bits (143), Expect = 5e-11 Identities = 38/207 (18%), Positives = 67/207 (32%), Gaps = 8/207 (3%) Query: 283 PSPSLKPEKKVAEAEKKVEEAKKKAEDQKEEDRRNYPTNTYKTLELEIAESDVEVKKAEL 342 + P A+ ++ A + P +T E S E K E Sbjct: 994 TTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEK 1053 Query: 343 ELVKEEAKEPQNEEKVKQAKAEVES--KQAEATRL--EKIKTDRKKAEEEAKRKAAEEDK 398 QN E K+AK+ V++ + E + E +T + +E A + E+ K Sbjct: 1054 NEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAK 1113 Query: 399 V-KEKPAEQPQPAPAPQPEKPAPKPEKPAPAPKPENPAEQPKAEKPADQQ---AEEDYAR 454 V EK E P+ P++ + +P P EN E + E A+ Sbjct: 1114 VETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAK 1173 Query: 455 RSEEEYNRLTQQQPPKTEKPAQPSTPK 481 + + + + P+ Sbjct: 1174 ETSSNVEQPVTESTTVNTGNSVVENPE 1200 Score = 44.7 bits (105), Expect = 1e-06 Identities = 42/221 (19%), Positives = 76/221 (34%), Gaps = 16/221 (7%) Query: 103 PKAELTSKAKAELDAAFEQFKKEPELTKKVAEAQKKVEEAKKKAEDQKEEDFRNYPTNTY 162 P A T E A E K+E + +K ++ E + + +E N NT Sbjct: 1027 PPAPATPSETTETVA--ENSKQESKTVEK---NEQDATETTAQNREVAKEAKSNVKANTQ 1081 Query: 163 KTIELEIAESDVKVKEAELELLKEEAKEHRDEGTIKQVEEKVKSEKAEATRLEEIKTDRE 222 E+A+S + KE + KE A ++E + KV++EK + + + Sbjct: 1082 ---TNEVAQSGSETKETQTTETKETATVEKEE------KAKVETEKTQEVPKVTSQVSPK 1132 Query: 223 EAKRKADAKLKEAVEKNVATSEQDKLKGRRKRGVLGEPATPDKKENDAKSSDSSVGEETL 282 + + + E +N T + + + E + N + S T Sbjct: 1133 QEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTG 1192 Query: 283 PSPSLKPEKKVAEA--EKKVEEAKKKAEDQKEEDRRNYPTN 321 S PE E+ K +++ R+ P N Sbjct: 1193 NSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHN 1233
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.0 bits (200), Expect = 4e-20 Identities = 37/119 (31%), Positives = 63/119 (52%), Gaps = 4/119 (3%) Query: 3 ILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKIQDLPIHLMVLDLMMPRKSGFEV 62 ILVADD+ IR + L+ GY V + + + I L+V D++MP ++ F++ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 63 LKEINQ-KHDIPVIVLSALGDETTQSQVFDLYADDHVTKPFSL---VLLVKRIKALIRR 117 L I + + D+PV+V+SA T + + A D++ KPF L + ++ R A +R Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.7 bits (77), Expect = 0.003 Identities = 34/172 (19%), Positives = 56/172 (32%), Gaps = 28/172 (16%) Query: 502 KYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKA 561 L +++ ++G+ A+ I R + R + + M G +G GK +A+A Sbjct: 127 SKLEDDSQDGMPLVGRSAAMQEIYRVLAR----LMQTDLTL---MITGESGTGKELVARA 179 Query: 562 LAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSV---- 617 L + + +M+ S L G E G T Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGH--------EKGAFTGAQTRSTGRFEQAE 231 Query: 618 ---LLFDEVEKAHPDIFNVLLQVLDDGVLT---DSKGRKVDFSNTIIIMTSN 663 L DE+ D LL+VL G T + D I+ +N Sbjct: 232 GGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVR---IVAATN 280