PredictBias

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score = 37.5 bits (87), Expect = 2e-05

		 Identities = 20/76 (26%), Positives = 30/76 (39%), Gaps = 7/76 (9%)

		

		Query: 2   GATKLLSEKLFHQANHHVQNRGTVFCSVRFGNVLGSRGS---VIPILFEQLMAGGPLTI- 57

		            ATK  +E + H  +H     G     +RF  V G  G     +    + ++ G  + + 

		Sbjct: 152 AATKKANELMAHTYSH---LYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVY 208

		

		Query: 58  TDKNMTRFFMSIDDAA 73

		               M R F  IDD A

		Sbjct: 209 NYGKMKRDFTYIDDIA 224

		

		

		>BCTERIALGSPH#Bacterial general secretion pathway protein H

		          signature.

		          Length = 170

		

		 Score = 38.8 bits (90), Expect = 2e-06

		 Identities = 14/56 (25%), Positives = 24/56 (42%), Gaps = 3/56 (5%)

		

		Query: 8  ENGFTLLESLIVLSLASVLLT-VLFTTVPPAYTHLAVRQKTEQLQKDIQLAQETAI 62

		          + GFTLLE +++L L  V    VL           A  Q   + +  ++  Q+  +

		Sbjct: 3  QRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAA--QTLARFEAQLRFVQQRGL 56

		

		

		>BCTERIALGSPG#Bacterial general secretion pathway protein G

		          signature.

		          Length = 145

		

		 Score = 39.9 bits (93), Expect = 3e-07

		 Identities = 14/60 (23%), Positives = 30/60 (50%), Gaps = 7/60 (11%)

		

		Query: 1  MLRLKNQDGFTLIEMLIVLFIVSILLLITIPNVTKHNQSIQHKGCEGLQNMVKAQVTAYE 60

		          M     Q GFTL+E+++V+ I+ +L  + +PN+  + +       +  +    + + A E

		Sbjct: 1  MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKE-------KADKQKAVSDIVALE 53

		

		

		>BCTERIALGSPF#Bacterial general secretion pathway protein F

		           signature.

		          Length = 408

		

		 Score = 83.3 bits (206), Expect = 6e-20

		 Identities = 57/339 (16%), Positives = 135/339 (39%), Gaps = 4/339 (1%)

		

		Query: 11  KDQAAFLKRLGEMTEKGYSLIEGLRLLQLQLHKRQLAELTDGIR-RLREGDAFYQVLEAL 69

		            D A   ++L  +      L E L  +  Q  K  L++L   +R ++ EG +    ++  

		Sbjct: 68  SDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLADAMKCF 127

		

		Query: 70  --SFHKEAVSICYFAEKHGELPGAMKQSGDLLQRKLMQTNQIKKMLRYPMFLISSVCVMF 127

		             SF +   ++    E  G L   + +  D  +++    ++I++ + YP  L      + 

		Sbjct: 128 PGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVVAIAVV 187

		

		Query: 128 YILQSLIIPQFSGIYQSMNMNTSGATAFIFAFFRHFHEACVLALSAAFCLFLYVWFLCKK 187

		            IL S+++P+    +  M      +T  +              L A    F+    + ++

		Sbjct: 188 SILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFRVMLRQ 247

		

		Query: 188 KSPQDKM-LIVVKIPLLGKAAVLFNSYFFSLQLSSLLKSGLSIYDSLTAFKEQSFLPFYR 246

		           +  +      ++ +PL+G+ A   N+  ++  LS L  S + +  ++    +     + R

		Sbjct: 248 EKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMSNDYAR 307

		

		Query: 247 EEAEMLITRLKAGETIESALSGHPCYEKDLAAAVSHGQANGLLHRELYTYSQFMMERLEQ 306

		               +    ++ G ++  AL     +   +   ++ G+ +G L   L   +         

		Sbjct: 308 HRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQDREFSS 367

		

		Query: 307 NAAKYTGILQPVIYGVVAGMILIVYMSMLMPMYQMMNQM 345

		                 G+ +P++   +A ++L + +++L P+ Q+   M

		Sbjct: 368 QMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406

		

		

		>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein

		           signature.

		          Length = 347

		

		 Score =  173 bits (440), Expect = 5e-51

		 Identities = 84/358 (23%), Positives = 146/358 (40%), Gaps = 48/358 (13%)

		

		Query: 2   SKVIGIDLGTTNSCVAVLEGG----EPTVIA-NAEGNRTTPSVVAFKNGERQVGEVAKRQ 56

		           S  + IDLGT N+ + V   G    EP+V+A   +   +  SV A       VG  AK+ 

		Sbjct: 10  SNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAA-------VGHDAKQM 62

		

		Query: 57  SITNPNTIMSVKRHMGTDYKVEIEGKDYTPQEVSAIILQHLKAYAESYLGETVSKAVITV 116

		               P  I +++       K  +    +  +++    ++ +     +       + ++ V

		Sbjct: 63  LGRTPGNIAAIR-----PMKDGVIADFFVTEKMLQHFIKQVH---SNSFMRPSPRVLVCV 114

		

		Query: 117 PAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDEDQTILVYDLGGGTFDV 176

		           P      ER+A +++ + AG     +I EP AAA+  GL    E    +V D+GGGT +V

		Sbjct: 115 PVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGL-PVSEATGSMVVDIGGGTTEV 173

		

		Query: 177 SVLELGDGVFEVRSTAGDNRLGGDDFDQVIIDHLVAEFKKENGIDLSKDKMALQRLKDAA 236

		           +V+ L   V      +   R+GGD FD+ II+++   +    G             +  A

		Sbjct: 174 AVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYGSLIG-------------EATA 215

		

		Query: 237 EKAKKDLS----GVSSTQISLPFITAGEAGPLHLELTLTRAKFEELSAHLVERTMAPVRQ 292

		           E+ K ++     G    +I +      E  P    L  +    E L   L     A V  

		Sbjct: 216 ERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLN-SNEILEALQEPLTGIVSA-VMV 273

		

		Query: 293 ALQDA--DLSASEIDK-VILVGGSTRIPAVQEAIKKETGKEAHKGVNPDEVVALGAAI 347

		           AL+    +L++   ++ ++L GG   +  +   + +ETG       +P   VA G   

		Sbjct: 274 ALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGK 331

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 30.4 bits (68), Expect = 0.005

		 Identities = 25/175 (14%), Positives = 55/175 (31%), Gaps = 7/175 (4%)

		

		Query: 2    SEEKQTAEQVEAAEQEEVTEQAEQAASQEQHEETAGQEEALQHQIDELQGLLDEKENKLL 61

		            ++E QT E  E A  E+  +   +    ++  +   Q    Q Q + +Q   +       

		Sbjct: 1092 TKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDP 1151

		

		Query: 62   RVQADFENYKRRSRLEMEAAQKYRSQNVVTEILPALDNFERALQVEAESEQTKSLLQGME 121

		             V       +  +  + E   K  S NV   +               E+ +  +      

		Sbjct: 1152 TVNIKEPQSQTNTTADTEQPAKETSSNVEQPV--TESTTVNTGNSVVENPENTTPATTQP 1209

		

		Query: 122  MVRRQLMDALEKEGVEAIEAVGQEFDP-----NLHQAVMQVEDENFGSNIVIEEL 171

		             V  +  +  +     ++ +V    +P     N    V   +  +  +N V+ + 

		Sbjct: 1210 TVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDA 1264

		

		

		>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE)

		           signature.

		          Length = 372

		

		 Score = 27.8 bits (61), Expect = 0.048

		 Identities = 26/111 (23%), Positives = 42/111 (37%), Gaps = 14/111 (12%)

		

		Query: 5   KRMNSALTYIEENLTNDIDFKEASRLAFCSEYHFKRMFSFLTGISLSEYIRRRRLTFAAF 64

		           +R    L +IE +L  DID  +AS    CS   F ++   LT + +   +R   L F + 

		Sbjct: 214 QRRLVVLDFIEGSLLTDIDANDAS----CSRLEFGQLLRRLTQLKM---LRSADLLFVST 266

		

		Query: 65  ELKDSSVKVID-------LAIKYGYHSPDSFARAFQNLHGISPSEAKHNGH 108

		            L  S  K  +       L +      P        ++ G++     H  H

		Sbjct: 267 LLSYSFTKAFNAEESSWLLLMLSLLQQPHEVDSLLADIIGLNALLLSHKEH 317

		

		

		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

		          Length = 173

		

		 Score =  257 bits (659), Expect = 2e-91

		 Identities = 135/173 (78%), Positives = 157/173 (90%)

		

		Query: 1   MITKMTRFNMKDFNKPNEPFVVSGRIIPSFEDNVWTYTEEKFAEPYVKKYDDEDIDVSYI 60

		           MI KMT  NMKDFNKPNEPFVV GR+IP+FE+ VWTYTEE+F++PY K+Y+D+D+DVSY+

		Sbjct: 1   MIMKMTHLNMKDFNKPNEPFVVFGRMIPAFENGVWTYTEERFSKPYFKQYEDDDMDVSYV 60

		

		Query: 61  EEEDKVVFFYYAENDCVGRSKLRSNWNGYALIEDIAVAEDYRKNGVGTALLHKAVEWAKE 120

		           EEE K  F YY EN+C+GR K+RSNWNGYALIEDIAVA+DYRK GVGTALLHKA+EWAKE

		Sbjct: 61  EEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKE 120

		

		Query: 121 NHLCGLMLETQDINVSACHFYAKNNFVVGAVDTMLYSNFSTANEIAVFWYCKF 173

		           NH CGLMLETQDIN+SACHFYAK++F++GAVDTMLYSNF TANEIA+FWY KF

		Sbjct: 121 NHFCGLMLETQDINISACHFYAKHHFIIGAVDTMLYSNFPTANEIAIFWYYKF 173

		

		

		>PF08280#M protein trans-acting positive regulator

		          Length = 530

		

		 Score = 32.1 bits (73), Expect = 0.007

		 Identities = 73/451 (16%), Positives = 145/451 (32%), Gaps = 68/451 (15%)

		

		Query: 7   RQKKILYLLLSEPDDYLVVQDFADRVRCSEKTIRNDLKTIEDFLNEHAQAQLIRKPGLGV 66

		            + +++ L        L + + A++   +   + +  + +  F  +     + ++     

		Sbjct: 45  SKCQLVVLFFKTS--SLPITEVAEKTGLTFLQLNHYCEELNAFFPDSLSMTIQKRMISCQ 102

		

		Query: 67  YLHISEQERSRLSRQIYNEHFTCGHKTDEERILH-IAYDLLMNSKPVSAKEIAAQHFVNR 125

		           + H S++       Q+Y              +L  +A+ +   S      + A  HF++ 

		Sbjct: 103 FTHPSKET---YLYQLY----------ASSNVLQLLAFLIKNGSHSRPLTDFARSHFLSN 149

		

		Query: 126 ASIKKDVSAVEEWLKRFDLILVSKQRLGLKIEGDEKNKRKALARISDLIDNAEFTSQFIK 185

		           +S  +   A+   L+ F+L L        KI G+E        RI  LI  A   S+F  

		Sbjct: 150 SSAYRMREALIPLLRNFELKLSKN-----KIVGEE-------YRIRYLI--ALLYSKF-- 193

		

		Query: 186 SKFLSYEADFVRKE-IKLLQKKHSIYFTDETFES---LLLHTLLTIRRIKMKQPVAI-SA 240

		                Y+     K  I       S +     + S        LL +   + +  V I   

		Sbjct: 194 -GIKVYDLTQQDKNIIHSFLSHSSTHLKTSPWLSESFSFYDILLALSWKRHQFSVTIPQT 252

		

		Query: 241 RQLDAVKKKKEY-EWTLACLKRLEPVFAIRFPEEEAVYLTLHIIGGKVRYPSQQEKKLDL 299

		           R    +KK   Y     +    +E    + F   +  YL L  I     + S Q     +

		Sbjct: 253 RIFQQLKKLFVYDSLKKSSRDIIETYCQLNFSAGDLDYLYLIYITANNSFASLQWTPEHI 312

		

		Query: 300 EDSELSKVVRHLINRVSELQMLDFHKDQELINGLNIHLDPVLKRLSY------------- 346

		                      L       ++L  +    L+  L      ++K L +             

		Sbjct: 313 RQ------CCQLFEENDTFRLL-LNPIITLLPNLKEQKASLVKALMFFSKSFLFNLQHFI 365

		

		Query: 347 --DLSVSNPMLHDIKKMYPYLFHLIIDVLEDINQTFDLYIPEEEAAYLTLHFQAAIERLR 404

		                  +P     +K+Y  L  ++ + +  +      Y+  +       +    +E++ 

		Sbjct: 366 PETNLFVSPYYKGNQKLYTSLKLIVEEWMAKLPG--KRYLNHKHFHLFCHY----VEQIL 419

		

		Query: 405 RNSHNPKRTIIVCHMGIGMSQLLRNKIERKF 435

		           RN   P   + V    I  + LL +   R F

		Sbjct: 420 RNIQPPLVVVFVASNFIN-AHLLTDSFPRYF 449

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 69.1 bits (169), Expect = 1e-15

		 Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 4/115 (3%)

		

		Query: 3   KVLIVDDEMLARDELAYLLKRTNEVSDINEAENIESAFDSMMDQKPDLLFLDVDLSGENG 62

		            +L+ DD+   R  L   L R     D+    N  + +  +     DL+  DV +  EN 

		Sbjct: 5   TILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62

		

		Query: 63  FDIAKRLKNMKNPPAVVFATAYDQF--ALKAFEVDALDYLTKPFDEERVRQTIRK 115

		           FD+  R+K  +    V+  +A + F  A+KA E  A DYL KPFD   +   I +

		Sbjct: 63  FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score =  216 bits (552), Expect = 3e-67

		 Identities = 62/216 (28%), Positives = 112/216 (51%), Gaps = 13/216 (6%)

		

		Query: 362 QLELGEAELQSKLLKDAEIKALQAQVNPHFLFNAINTISALCRTDVEKTRKLLLQLSVYF 421

		           Q E+ + ++   + ++A++ AL+AQ+NPHF+FNA+N I AL   D  K R++L  LS   

		Sbjct: 146 QAEIDQWKMA-SMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELM 204

		

		Query: 422 RSNLQGARQLLIPLSKELNHLQAYLSLEQARFPGKYKISLEIERGLEDIEIPPFVLQILV 481

		           R +L+ +    + L+ EL  + +YL L   +F  + +   +I   + D+++PP ++Q LV

		Sbjct: 205 RYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLV 264

		

		Query: 482 ENALRHAFSRKQDSCAVNVSVVSAGQSVLMRVGDNGRGIDVELLSVLGKCPLPSKEGTGT 541

		           EN ++H  ++      + +       +V + V + G                 +KE TGT

		Sbjct: 265 ENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN-----------TKESTGT 313

		

		Query: 542 ALYNLNQRLIGLFGPKAALRLESETGKGTDVSFELP 577

		            L N+ +RL  L+G +A ++L  + GK       +P

		Sbjct: 314 GLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348

		

		

		>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase

		           signature.

		          Length = 572

		

		 Score = 73.3 bits (180), Expect = 1e-15

		 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 2/78 (2%)

		

		Query: 503 KMTDGAVLVASSTDRDMIASL--EKASALITEEGGLTSHAAVVGLSLGIPVIVGLENATS 560

		            + +  V++A        A L  +      T+ GG TSH+A++  SL IP +VG +  T 

		Sbjct: 152 TIAEETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHSAIMSRSLEIPAVVGTKEVTE 211

		

		Query: 561 VLTEGQVITVDAARGAVY 578

		            +  G ++ VD   G V 

		Sbjct: 212 KIQHGDMVIVDGIEGIVI 229

		

		

		>FbpA_PF05833#Fibronectin-binding protein

		          Length = 577

		

		 Score = 29.1 bits (65), Expect = 0.029

		 Identities = 9/37 (24%), Positives = 18/37 (48%), Gaps = 3/37 (8%)

		

		Query: 137 IGFDTALNTVIDAIDKIRDTATSHERTYVIEVMGRHA 173

		           I  D  +    ++ D++         + +IE+MGRH+

		Sbjct: 94  INQDRIVVIDFESTDELGFN---SIYSLIIEIMGRHS 127

		

		

		>PF01540#Adhesin lipoprotein

		          Length = 475

		

		 Score = 23.9 bits (51), Expect = 0.047

		 Identities = 11/34 (32%), Positives = 19/34 (55%)

		

		Query: 4   KDSWWKDTAKDQKTDDKDMGFEPRRIQNDVNELK 37

		           K +W K+ A+ +  DDK +  E ++I+    EL 

		Sbjct: 220 KKAWSKELAEIKAEDDKKLAEENQKIKEGAKELL 253

		

		

		>TYPE3OMBPROT#Type III secretion system outer membrane B protein

		           family signature.

		          Length = 538

		

		 Score = 28.9 bits (64), Expect = 0.011

		 Identities = 9/30 (30%), Positives = 15/30 (50%)

		

		Query: 73  VPGGWAPDKLRRYPEVLDIIRTMNEQKKPI 102

		           V GGWA + + + P   + +  +  Q K I

		Sbjct: 375 VIGGWAAEAIEKNPPCKNDVIYLANQIKEI 404

		

		

		>ISCHRISMTASE#Isochorismatase signature.

		          Length = 312

		

		 Score = 48.9 bits (116), Expect = 2e-09

		 Identities = 24/70 (34%), Positives = 37/70 (52%)

		

		Query: 103 KTRYSAFAGTDLELKLRERQITELHFAGLCTDICVLHTAVDAYNKGFQIVIHQNAVASFN 162

		           K RYSAF  T+L   +R+    +L   G+   I  L TA +A+ +  +     +AVA F+

		Sbjct: 123 KWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFS 182

		

		Query: 163 PEGHEWALSH 172

		            E H+ AL +

		Sbjct: 183 LEKHQMALEY 192

		

		

		>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature.

		          Length = 1147

		

		 Score = 28.1 bits (62), Expect = 0.017

		 Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 5/46 (10%)

		

		Query: 87  GVRRHAGEQATVINKLVIDFNRFVSE-----AKDFQKAEEKEKQKK 127

		           G++R   ++   +NK + DF++   E      KDF KAEE  K  K

		Sbjct: 678 GIKRELSDKLENVNKNLKDFDKSFDEFKNGKNKDFSKAEETLKALK 723

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score = 30.0 bits (67), Expect = 0.010

		 Identities = 17/101 (16%), Positives = 33/101 (32%), Gaps = 20/101 (19%)

		

		Query: 45  QLSALYPEKYIYDVAGFPKIRAQELVNNLKEQMAKFDQTIC--------------LEQAV 90

		           +  A + E +  DV     I   E+   ++ +M   D  +                E+  

		Sbjct: 53  KAEARHAEAFPADVRDSAAID--EITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWE 110

		

		Query: 91  ESVEKQADGVFKLVTNSETHY----SKTVIITAGNGAFKPR 127

		            +    + GVF    +   +     S +++    N A  PR

		Sbjct: 111 ATFSVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPR 151

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score = 62.8 bits (152), Expect = 8e-14

		 Identities = 40/195 (20%), Positives = 81/195 (41%), Gaps = 12/195 (6%)

		

		Query: 3   LTGNTILITGGNAGIGLAFAERFLKAGNKVIVTGRREHALQKAKET------YPELITYV 56

		           + G    ITG   GIG A A      G  +         L+K   +      + E   + 

		Sbjct: 6   IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE--AFP 63

		

		Query: 57  SDLSIPSERISLFDWVKKNYPEVNVLVNNAGIQQRFHVLKADAKDNWDYFNKEITTNIEA 116

		           +D+   +    +   +++    +++LVN AG+  R  ++ + + + W+      + N   

		Sbjct: 64  ADVRDSAAIDEITARIEREMGPIDILVNVAGVL-RPGLIHSLSDEEWE---ATFSVNSTG 119

		

		Query: 117 PFHLSMLFAPFFAGKEDAAFINVSSGLAFTPLAIAPIYSATKAALHSFTMSLRHQLSDSS 176

		            F+ S   + +   +   + + V S  A  P      Y+++KAA   FT  L  +L++ +

		Sbjct: 120 VFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179

		

		Query: 177 VEVIEVAPPAVNTDL 191

		           +    V+P +  TD+

		Sbjct: 180 IRCNIVSPGSTETDM 194

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score =  104 bits (260), Expect = 7e-29

		 Identities = 69/261 (26%), Positives = 109/261 (41%), Gaps = 17/261 (6%)

		

		Query: 5   LERKLVLITGSTSGIGKAAAKSFLAEGAEVIINGRKKETVERTVEELSAYG-TVHGIAAD 63

		           +E K+  ITG+  GIG+A A++  ++GA +       E +E+ V  L A         AD

		Sbjct: 6   IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65

		

		Query: 64  LSRQDEADDLIKR-AGGIGEVDILVNNLGFFEVKDFAEVSDDEWTRYFEVNVMSAVRLCR 122

		           +      D++  R    +G +DILVN  G         +SD+EW   F VN        R

		Sbjct: 66  VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125

		

		Query: 123 RFLPQMLERNSGRILNISSEAGVKPLAQMIPYSMTKTALISLSRGMAEMTKGTNVTVNSV 182

		                M++R SG I+ + S     P   M  Y+ +K A +  ++ +       N+  N V

		Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185

		

		Query: 183 LPGPT-----WTEGVASYMEGAAKAAGEDTNSFVRDYFKVNEPTSLIQRYATPEEVANTI 237

		            PG T     W+                +T       FK   P   +++ A P ++A+ +

		Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLET-------FKTGIP---LKKLAKPSDIADAV 235

		

		Query: 238 VFLASSAASAINGTAQRVEGG 258

		           +FL S  A  I      V+GG

		Sbjct: 236 LFLVSGQAGHITMHNLCVDGG 256

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 36.4 bits (84), Expect = 2e-04

		 Identities = 19/106 (17%), Positives = 39/106 (36%), Gaps = 24/106 (22%)

		

		Query: 478 ILENLLANAVKH----NKKGIAIRVVLEESAEQLILKVKDNGRGMDDETIHQLFNRYYRG 533

		           +++ L+ N +KH      +G  I +   +    + L+V++ G      T           

		Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTK---------- 308

		

		Query: 534 TNTKGPSEGTGLGLAIAKE-LVHLH--NGTIHVNSRISAGTVITIL 576

		                  E TG GL   +E L  L+     I ++ +      + ++

		Sbjct: 309 -------ESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLI 347

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 97.2 bits (242), Expect = 2e-25

		 Identities = 36/130 (27%), Positives = 64/130 (49%), Gaps = 2/130 (1%)

		

		Query: 1   MENASILIVDDEKAIVDMVKRVLVKEGYHNIKTAGSAEEAIEFVKHETADLLVLDVMMEG 60

		           M  A+IL+ DD+ AI  ++ + L + GY +++   +A     ++     DL+V DV+M  

		Sbjct: 1   MTGATILVADDDAAIRTVLNQALSRAGY-DVRITSNAATLWRWIAAGDGDLVVTDVVMPD 59

		

		Query: 61  MSGFEACTEIRN-YTDAPIFFLTARSSDADKLSGFALGADDYITKPFNPLELAARIRATL 119

		            + F+    I+    D P+  ++A+++    +     GA DY+ KPF+  EL   I   L

		Sbjct: 60  ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119

		

		Query: 120 KRTYKREEKT 129

		               +R  K 

		Sbjct: 120 AEPKRRPSKL 129

		

		

		>OMS28PORIN#OMS28 porin signature.

		          Length = 257

		

		 Score = 27.1 bits (59), Expect = 0.041

		 Identities = 12/15 (80%), Positives = 13/15 (86%)

		

		Query: 21 NVLEHSDEKDAKSLD 35

		          NVLEHSD+KD K LD

		Sbjct: 37 NVLEHSDQKDNKKLD 51

		

		

		>TCRTETB#Tetracycline resistance protein TetB signature.

		          Length = 458

		

		 Score = 51.4 bits (123), Expect = 3e-09

		 Identities = 65/381 (17%), Positives = 125/381 (32%), Gaps = 55/381 (14%)

		

		Query: 24  FTVANVYLNQTLLVSMANTFHVSENNIGIVATLTQVGYALGNLLLVPLGDIFERRKLILS 83

		           F+V N  +    L  +AN F+    +   V T   + +++G  +   L D    ++L+L 

		Sbjct: 25  FSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLF 84

		

		Query: 84  LLSIVCIILAATALSMN-VTWLIAANLILGF-VTIVPQIIVPLAANLASEENRGKVLGNV 141

		            + I C       +  +  + LI A  I G      P +++ + A    +ENRGK  G +

		Sbjct: 85  GIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLI 144

		

		Query: 142 AIGLVCGILGARFISGFADSHFGWRSMYWASFAGTMIMIILMAMYLPKSKGNH------- 194

		              +  G      I G    +  W   Y        I+ +   M L K +          

		Sbjct: 145 GSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVRIKGHFDIK 202

		

		Query: 195 -----------------------------------AMQYKTLLASLGPLFKKEKVLQKAC 219

		                                                  K     + P   K        

		Sbjct: 203 GIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGV 262

		

		Query: 220 LSQGMMFGSFSAFWTTLIFLLNT----SPYSYGSTAAGLIGLVGIAGAFATPMIGRVIDK 275

		           L  G++FG+ + F + + +++      S    GS    +I    ++      + G ++D+

		Sbjct: 263 LCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGS---VIIFPGTMSVIIFGYIGGILVDR 319

		

		Query: 276 KGSKFANTLCMFISLIAFLTLIFLGYWLPGLLLGALLVTVGTQA--NQVACQAAIFQLSS 333

		           +G  +   + +    ++FLT  FL       +   ++  +G  +    V        L  

		Sbjct: 320 RGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQ 379

		

		Query: 334 EKRSRLNGLYMVSTFLGGSLG 354

		           ++      L   ++FL    G

		Sbjct: 380 QEAGAGMSLLNFTSFLSEGTG 400

		

		

		>BCTERIALGSPC#Bacterial general secretion pathway protein C

		           signature.

		          Length = 272

		

		 Score = 28.8 bits (64), Expect = 0.027

		 Identities = 22/97 (22%), Positives = 46/97 (47%), Gaps = 16/97 (16%)

		

		Query: 243 SVKIILEDGKKVNVGSREQAEAFLEQVTQ--PYKLITQKTG----VIAGTKEETA----- 291

		           S+ II +D ++ + G  E+   +  ++    P +++ Q  G    +   ++E++      

		Sbjct: 109 SIAIISKDNEQFSRGVNEEVPGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQEDSGSDGVP 168

		

		Query: 292 -AELRRLSVQ---YSITDFVILSPIKNAEEKRLSYRL 324

		            A++     Q    +++D+V  SPI N + K   YRL

		Sbjct: 169 GAQVNEQLQQRASTTMSDYVSFSPIMN-DNKLQGYRL 204

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score =  123 bits (309), Expect = 4e-36

		 Identities = 75/256 (29%), Positives = 127/256 (49%), Gaps = 7/256 (2%)

		

		Query: 5   LKGKTALVTGSTSGIGKAIAASLIAEGAAVIINGRREEKVNETIRELEKQTPDARLYPA- 63

		           ++GK A +TG+  GIG+A+A +L ++GA +       EK+ + +  L+ +   A  +PA 

		Sbjct: 6   IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65

		

		Query: 64  -AFDLGTAEGCGAIFQQYPDVDILVNNLGIFEPAEYFDIPDEEWLRFFEVNIMSGVRLTR 122

		                   E    I ++   +DILVN  G+  P     + DEEW   F VN       +R

		Sbjct: 66  VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125

		

		Query: 123 RYAKRMIERKEGRVIFIASEAAVMPSQEMAHYSATKTTQLSLSRSLAELTEGTNVTVNTV 182

		             +K M++R+ G ++ + S  A +P   MA Y+++K   +  ++ L       N+  N V

		Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185

		

		Query: 183 MPGSTKTEGVETMLESLYPGENLTAAEAERRFMKENRPTSIIQRLIRPEEIAHFVAFLSS 242

		            PGST+T+    M  SL+  EN  A +  +  ++  +    +++L +P +IA  V FL S

		Sbjct: 186 SPGSTETD----MQWSLWADEN-GAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240

		

		Query: 243 PLSSAINGSALRIDGG 258

		             +  I    L +DGG

		Sbjct: 241 GQAGHITMHNLCVDGG 256

		

		

		>SECGEXPORT#Protein-export SecG membrane protein signature.

		          Length = 110

		

		 Score = 43.4 bits (102), Expect = 3e-09

		 Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 4/76 (5%)

		

		Query: 1  MHTLLITLLVIVSIALIIVVLLQTSKSAGLSGAISGGAE-QLFGKQKARGLDLILHRTTV 59

		          M+  L+ + +IV+I L+ +++LQ  K A +  +   GA   LFG   + G    + R T 

		Sbjct: 1  MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFG---SSGSGNFMTRMTA 57

		

		Query: 60 VLAVLFFVLTISLAYI 75

		          +LA LFF++++ L  I

		Sbjct: 58 LLATLFFIISLVLGNI 73

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 31.0 bits (70), Expect = 0.010

		 Identities = 18/101 (17%), Positives = 36/101 (35%), Gaps = 25/101 (24%)

		

		Query: 362 NAVDY----TPEGGEIRVDVLCTDSALHLAVSDSGSGFSPEALKRATQLFYTEDKSRHSA 417

		           N + +     P+GG+I +     +  + L V ++GS                     ++ 

		Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALK-----------------NTK 308

		

		Query: 418 GHHGMGLTFAHHVVHLHHGE---LILENQESGGARAEIRIP 455

		              G GL      + + +G    + L  ++ G   A + IP

		Sbjct: 309 ESTGTGLQNVRERLQMLYGTEAQIKLSEKQ-GKVNAMVLIP 348

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 80.6 bits (199), Expect = 7e-20

		 Identities = 36/122 (29%), Positives = 59/122 (48%), Gaps = 2/122 (1%)

		

		Query: 2   ANILAIDDEKDILVLIRNILQRDQHTVTILEKAEDQSLDFFQG-YDLILLDVMMPGTDGI 60

		           A IL  DD+  I  ++   L R  + V I   A         G  DL++ DV+MP  +  

		Sbjct: 4   ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63

		

		Query: 61  ELCRRIR-PLVDSPILFLTAKSDEESIVKGLMTGADDYITKPFGVQELMARVNAHVRRER 119

		           +L  RI+    D P+L ++A++   + +K    GA DY+ KPF + EL+  +   +   +

		Sbjct: 64  DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123

		

		Query: 120 RE 121

		           R 

		Sbjct: 124 RR 125

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score = 80.2 bits (198), Expect = 2e-18

		 Identities = 53/282 (18%), Positives = 95/282 (33%), Gaps = 52/282 (18%)

		

		Query: 270 TILVTGAGGSIGSEICRQISAFLPREIVLLGHGENSIHSVHT-------ELSARFGKEVL 322

		             LVTGA G IG  + +     L       GH    I +++        +       +  

		Sbjct: 2   KYLVTGAAGFIGFHVSK---RLLEA-----GHQVVGIDNLNDYYDVSLKQARLELLAQPG 53

		

		Query: 323 FHAEIADIQDRDKIFTLMKKYEPHVVYHAAAHKHVPLMEHNPEEAVKNNIIGTKNVAEAA 382

		           F     D+ DR+ +  L        V+ +     V     NP     +N+ G  N+ E  

		Sbjct: 54  FQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGC 113

		

		Query: 383 DMCGTETFVLISS---------------DKAVNPANVMGATKRFAEMVIMNLGKVSRTKF 427

		                +  +  SS               D   +P ++  ATK+  E++      +     

		Sbjct: 114 RHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPA 173

		

		Query: 428 AAVRFGNVLGSRGS---VIPIFKKQIEKGGPVTV-THPAMTRYFMTIPEASRLVIQA--- 480

		             +RF  V G  G     +  F K + +G  + V  +  M R F  I + +  +I+    

		Sbjct: 174 TGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDV 233

		

		Query: 481 ------------GALAKGR---QIFVLDMGEPVKIVDLAKNL 507

		                       G  A      +++ +    PV+++D  + L

		Sbjct: 234 IPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQAL 275

		

		

		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

		          Length = 173

		

		 Score = 52.6 bits (126), Expect = 3e-11

		 Identities = 24/110 (21%), Positives = 46/110 (41%), Gaps = 7/110 (6%)

		

		Query: 38  KAYLENAFRSEQLKKELSNLSSQFYFVYYHDDLAGYVKVNMNEAQSEKMGEDSLEIERIY 97

		           K Y +     +     +       +  Y  ++  G +K+  N             IE I 

		Sbjct: 44  KPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSN-------WNGYALIEDIA 96

		

		Query: 98  IRKNHQKHGLGKYLLNEAVKIATAHNKKKIWLGVWEKNENAIAFYQKMGF 147

		           + K+++K G+G  LL++A++ A  ++   + L   + N +A  FY K  F

		Sbjct: 97  VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 34.0 bits (78), Expect = 0.001

		 Identities = 37/191 (19%), Positives = 73/191 (38%), Gaps = 15/191 (7%)

		

		Query: 42  SATGIIFSVNAVFALCMQPLYGFISDKLGLKKKILFMISCLLIFTGPFYIFVYGPLLQYN 101

		           +  GI+ ++ A+      P+ G +SD+ G  ++ + ++S L      + I    P L + 

		Sbjct: 43  AHYGILLALYALMQFACAPVLGALSDRFG--RRPVLLVS-LAGAAVDYAIMATAPFL-WV 98

		

		Query: 102 VFLGAVVGGLYLGAAFLAGIGAIETYIEKVSRKYDFEYGKSRMWGSLGWAAAAFFAGQLF 161

		           +++G +V G+  GA        I    +   R   F +  +      G  A     G + 

		Sbjct: 99  LYIGRIVAGI-TGATGAVAGAYIADITDGDERARHFGFMSACF--GFGMVAGPVLGGLMG 155

		

		Query: 162 NINPNINFWIASV---SAVILTAIIM--SVKIE---MTDHEKNRADSVRLKDVGRLFLLR 213

		             +P+  F+ A+       +    ++  S K E   +     N   S R      +    

		Sbjct: 156 GFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAAL 215

		

		Query: 214 DFWFFMMYIIG 224

		              FF+M ++G

		Sbjct: 216 MAVFFIMQLVG 226

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 28.6 bits (64), Expect = 0.027

		 Identities = 9/37 (24%), Positives = 16/37 (43%)

		

		Query: 3   EKDWIVLITLFEEKNMTKAAERLYMTQPALSYRLKNL 39

		           E   I+        N  KAA+ L + +  L  +++ L

		Sbjct: 437 EYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL 473

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 50.6 bits (121), Expect = 6e-09

		 Identities = 65/401 (16%), Positives = 129/401 (32%), Gaps = 62/401 (15%)

		

		Query: 23  LVILSFAYFFDFIDLNTFSYAAPSLLKEWNISTHTIA---FITSVSYFGMFIGASAGGWF 79

		           L+++      D + +       P LL++   S    A    + ++     F  A   G  

		Sbjct: 7   LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66

		

		Query: 80  SDRFGRKKGLILVVTFFSFFSLLSSLAWNPEILGVFRFLTSLGIGATTIVASTYISEFFP 139

		           SDRFGR+  L++ +   +    + + A    +L + R +  +  GAT  VA  YI++   

		Sbjct: 67  SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI-TGATGAVAGAYIADITD 125

		

		Query: 140 SATKGK---YQAICITIGICGIPAAGWVAKLVVPSASYGWRFIFLFGAV--GIFFPLIAR 194

		              + +   + + C   G+   P  G +         +     F   A   G+ F     

		Sbjct: 126 GDERARHFGFMSACFGFGMVAGPVLGGLM------GGFSPHAPFFAAAALNGLNFLTGCF 179

		

		Query: 195 KLEESPKWLDTKGKSEQAHRILLELEAKAEKEKGELPEPAPALRSRQTAVKSVPYRTLFQ 254

		            L ES K                              E  P  R     + S  +     

		Sbjct: 180 LLPESHK-----------------------------GERRPLRREALNPLASFRWARGM- 209

		

		Query: 255 KPLAGRTFVLMTMWAASTIAIQGFGTWVPTLLVKEGVSMDESIVYVTLGTIGAPLGALIA 314

		             +A    V   M       +      +  +  ++    D + + ++L   G  L +L  

		Sbjct: 210 TVVAALMAVFFIMQ-----LVGQVPAALWVIFGEDRFHWDATTIGISLAAFGI-LHSLAQ 263

		

		Query: 315 SQISDRVDRKWA---ISVLSLIIMALGF----FYGINPLPMVIVICGFLMHMFERTFSSI 367

		           + I+  V  +       +L +I    G+    F     +   I++      +      ++

		Sbjct: 264 AMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAM 323

		

		Query: 368 AYAYTPELYPVEARASGNGLTYGVGRLANVAGPFVVSFLYS 408

		                 E    E +    G    +  L ++ GP + + +Y+

		Sbjct: 324 LSRQVDE----ERQGQLQGSLAALTSLTSIVGPLLFTAIYA 360

		

		

		>TRNSINTIMINR#Translocated intimin receptor (Tir) signature.

		          Length = 549

		

		 Score = 29.7 bits (66), Expect = 0.011

		 Identities = 16/65 (24%), Positives = 23/65 (35%), Gaps = 11/65 (16%)

		

		Query: 160 KGRPVWVITTTSFKPVDNMQTWNTP-NGKIDVTF----------SMHSVAVTGYDHDYVY 208

		           + +P    TTT+   V   QT   P +    +            S  SVA T +      

		Sbjct: 389 RNQPAEQTTTTTTHTVVQQQTGGIPQHKVALMPQERRRFSDRRDSQGSVASTHWSDSSSE 448

		

		Query: 209 VNDPY 213

		           V +PY

		Sbjct: 449 VVNPY 453

		

		

		>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE)

		           signature.

		          Length = 372

		

		 Score = 31.6 bits (71), Expect = 0.001

		 Identities = 16/73 (21%), Positives = 37/73 (50%)

		

		Query: 24  FLKVMKNFIIIQIARYTPFLSVKNWLYRTFLKMNVGKQTSFALMVMPDIMFPEKITVGEN 83

		           F ++++    +++ R    L V   L  +F K    +++S+ L+++  +  P ++     

		Sbjct: 243 FGQLLRRLTQLKMLRSADLLFVSTLLSYSFTKAFNAEESSWLLLMLSLLQQPHEVDSLLA 302

		

		Query: 84  SIIGYNTTILAHE 96

		            IIG N  +L+H+

		Sbjct: 303 DIIGLNALLLSHK 315

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 68.9 bits (168), Expect = 9e-17

		 Identities = 34/172 (19%), Positives = 68/172 (39%), Gaps = 12/172 (6%)

		

		Query: 7   TKERIIQTSAYLFQIQGYHATGLNQIIKESGAPRGSVYHHFPNGKAELAIAAIK-YTGRC 65

		           T++ I+  +  LF  QG  +T L +I K +G  RG++Y HF + K++L     +      

		Sbjct: 12  TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKD-KSDLFSEIWELSESNI 70

		

		Query: 66  VEKQIQNSMSQFADPI----EAIQHFIHVTAEQFNDPQNIEGVPVGLL-AGETALINETL 120

		            E +++       DP+    E + H +  T  +      +E +       GE A++ +  

		Sbjct: 71  GELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130

		

		Query: 121 RCTCVEVFKKWTDVFAAKFLEHGF-----EQEEAEKLGVTINSMIEGAIMFS 167

		           R  C+E + +                    +  A  +   I+ ++E  +   

		Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAP 182

		

		

		>adhesinb#Adhesin B signature.

		          Length = 310

		

		 Score = 26.0 bits (57), Expect = 0.017

		 Identities = 9/37 (24%), Positives = 18/37 (48%)

		

		Query: 2   EKDPENAQVTEESLRNLIREQKRMNSEMLAELEQIKA 38

		           EKDP N +  E++L+  + +   ++ E   +   I  

		Sbjct: 161 EKDPANKETYEKNLKAYVEKLSALDKEAKEKFNNIPG 197

		

		

		>PF03944#delta endotoxin

		          Length = 633

		

		 Score = 31.6 bits (71), Expect = 0.008

		 Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 10/93 (10%)

		

		Query: 206 DQLGFAVDDATNELTANAEGKNAKFTFNGLEMTKTSNNFTINGIKYTLNSVTDSNKTVTI 265

		           D L F  ++ T   T    G +         +  ++   TING  YT  +V         

		Sbjct: 521 DSLRFEQNNTTARYTLRGNGNSYNLYLRVSSIGNSTIRVTINGRVYTATNV--------- 571

		

		Query: 266 NSTTDTDGIFDNIKDFVD-KYNTLIKSANEKVT 297

		           N+TT+ DG+ DN   F D     ++ S+N  V 

		Sbjct: 572 NTTTNNDGVNDNGARFSDINIGNVVASSNSDVP 604

		

		

		>FLAGELLIN#Flagellin signature.

		          Length = 507

		

		 Score =  157 bits (397), Expect = 1e-46

		 Identities = 87/268 (32%), Positives = 131/268 (48%), Gaps = 4/268 (1%)

		

		Query: 1   MRINHNIAALNTSRQLNAGSNSAAKNMEKLSSGLRINRAGDDAAGLAISEKMRSQIRGLD 60

		             IN N  +L T   LN   +S +  +E+LSSGLRIN A DDAAG AI+ +  S I+GL 

		Sbjct: 2   QVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLT 61

		

		Query: 61  MASKNAQDGISLIQTAEGALNETHSILQRMSELATQAANDTNTTSDRAELQKEMDQLSSE 120

		            AS+NA DGIS+ QT EGALNE ++ LQR+ EL+ QA N TN+ SD   +Q E+ Q   E

		Sbjct: 62  QASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEE 121

		

		Query: 121 VTRISTDTEFNTKKLLDGTATDLTFQIGANEGQTMKLSINKMDSESLAVG---TATAGID 177

		           + R+S  T+FN  K+L      +  Q+GAN+G+T+ + + K+D +SL +           

		Sbjct: 122 IDRVSNQTQFNGVKVLSQDNQ-MKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEA 180

		

		Query: 178 ISTSADAASTALTTIKTAIDTVSSERAKLGAVQNRLEHTINNLGTSSENLTSAESRIRDV 237

		                 ++   +T   T     +  R  + +     + T   +        +      D 

		Sbjct: 181 TVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDD 240

		

		Query: 238 DMASEMMEYTKNNILTQASQAMLAQANQ 265

		              +  ++  K    T  +    A A  

		Sbjct: 241 AENNTAVDLFKTTKSTAGTAEAKAIAGA 268

		

		

		

		 Score = 97.0 bits (241), Expect = 6e-25

		 Identities = 49/186 (26%), Positives = 82/186 (44%)

		

		Query: 90  MSELATQAANDTNTTSDRAELQKEMDQLSSEVTRISTDTEFNTKKLLDGTATDLTFQIGA 149

		           +     Q++ +  T+    +   +    +        +     K     T     +   A

		Sbjct: 322 VDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESKITVNGAEYTANA 381

		

		Query: 150 NEGQTMKLSINKMDSESLAVGTATAGIDISTSADAASTALTTIKTAIDTVSSERAKLGAV 209

		              +           ++ +  +     D + +  + +  L +I +A+  V + R+ LGA+

		Sbjct: 382 AGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPLASIDSALSKVDAVRSSLGAI 441

		

		Query: 210 QNRLEHTINNLGTSSENLTSAESRIRDVDMASEMMEYTKNNILTQASQAMLAQANQQPQQ 269

		           QNR +  I NLG +  NL SA SRI D D A+E+   +K  IL QA  ++LAQANQ PQ 

		Sbjct: 442 QNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKAQILQQAGTSVLAQANQVPQN 501

		

		Query: 270 VLQLLK 275

		           VL LL+

		Sbjct: 502 VLSLLR 507

		

		

		>FLAGELLIN#Flagellin signature.

		          Length = 507

		

		 Score = 67.8 bits (165), Expect = 7e-15

		 Identities = 46/244 (18%), Positives = 98/244 (40%), Gaps = 7/244 (2%)

		

		Query: 1   MRVTQGMIAKNSLRFIGSSYDKLDRLQQQVSTGKKITKASDDPVVAMKGMQYRTQLAQVN 60

		             +    ++  +   +  S   L    +++S+G +I  A DD        ++ + +  + 

		Sbjct: 2   QVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLT 61

		

		Query: 61  QYQRNVSQGFTWLENSESSVNSETDIMGKIRDLMVQAKSDSNGETELKAIGTEIGQLKKQ 120

		           Q  RN + G +  + +E ++N   + + ++R+L VQA + +N +++LK+I  EI Q  ++

		Sbjct: 62  QASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEE 121

		

		Query: 121 LVSVAN-TQVNGRYLFNGTNSDVPPITENADGTYTYNYENYTGASDVNINISNGAVLKVN 179

		           +  V+N TQ NG  + +  N     +  N   T T + +     S             VN

		Sbjct: 122 IDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKS------LGLDGFNVN 175

		

		Query: 180 SDPNSAFGGVAQNGDNVFEFLNSLEASLSKGTLSEADSDQILSDIDGFTDKMNAEKSNIG 239

		               +  G +  +  NV  +      +        + +    +      DK+    +N  

		Sbjct: 176 GPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQ 235

		

		Query: 240 ARTN 243

		             T+

		Sbjct: 236 LTTD 239

		

		

		

		 Score = 30.8 bits (69), Expect = 0.008

		 Identities = 36/272 (13%), Positives = 83/272 (30%), Gaps = 17/272 (6%)

		

		Query: 24  DRLQQQVSTGKKITKASDDPVVAMKGMQYRTQLAQVNQYQRNVSQGFTWLENSESSVNSE 83

		                + +T   + K +       +       +    +      +G T+  ++++  +  

		Sbjct: 237 TTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGN 296

		

		Query: 84  TDIMGKIRD--LMVQAKSDSNGETELKAIGTEIGQLKKQLVSVANTQVNGRYLFNGTNSD 141

		             +   I    + +     + G   + A   +           ++  V    +      D

		Sbjct: 297 GKVSTTINGEKVTLTVADITAGAANVDAATLQ-----------SSKNVYTSVVNGQFTFD 345

		

		Query: 142 VPPITENADGTYTYNYENYTGASDVNINISNGAVLKVNSDPNSAFGGVAQNGDNVFEFLN 201

		               T+N     +    N     +  I ++        +       G     D     ++

		Sbjct: 346 --DKTKNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVS 403

		

		Query: 202 SLEASLSKGTLSEADSDQILSDIDGFTDKMNAEKSNIGARTNRLELIQTRLESQAATAEK 261

		           +L    +        +   L+ ID    K++A +S++GA  NR +   T L +       

		Sbjct: 404 TLINEDAAAAKKSTAN--PLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNS 461

		

		Query: 262 VLSDNEDVEMEDVIVDYLSQQTVHRAALSVNA 293

		             S  ED +    + +    Q + +A  SV A

		Sbjct: 462 ARSRIEDADYATEVSNMSKAQILQQAGTSVLA 493

		

		

		>FLGHOOKAP1#Flagellar hook-associated protein signature.

		          Length = 546

		

		 Score =  175 bits (446), Expect = 8e-51

		 Identities = 126/550 (22%), Positives = 213/550 (38%), Gaps = 66/550 (12%)

		

		Query: 7   GLETARRALSAQQTALSTVSNNVANANTEGYTRQRVTLQSTSPYPAVSKNSDLTAGQIGT 66

		            +  A   L+A Q AL+T SNN+++ N  GYTRQ   +   +             G +G 

		Sbjct: 3   LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLG-------AGGWVGN 55

		

		Query: 67  GVKAGSVERVRDSFLDYQYRTENTKLGYYTARSNSLSQMEGVMKELDDNGLNGSLSSFWN 126

		           GV    V+R  D+F+  Q R   T+    TAR   +S+++ ++     + L   +  F+ 

		Sbjct: 56  GVYVSGVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLST-STSSLATQMQDFFT 114

		

		Query: 127 ALQDLATNPENTGARSVLQEQGKSLAESFNYISTSLTNIQGDIKKNLDNTADQVNSILNQ 186

		           +LQ L +N E+  AR  L  + + L   F      L +    +   +  + DQ+N+   Q

		Sbjct: 115 SLQTLVSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQ 174

		

		Query: 187 LNDLNNQIAAVEPSGML--PNDLYDQRDRLIDQLSSMANIKV------------------ 226

		           +  LN+QI+ +   G    PN+L DQRD+L+ +L+ +  ++V                  

		Sbjct: 175 IASLNDQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSL 234

		

		Query: 227 -------------SYNKSGGHALATAEGTVNVELLNG---NNNSLGTLLDGNTKTVSEMK 270

		                        S        +A  +GT     +     N  SLG +L   ++ + + +

		Sbjct: 235 VQGSTARQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTR 294

		

		Query: 271 INYDKDSGLVSSVSVGSSTVNADAFTGKGSLLGLIESYGYMSNGEEKGLYPEMLTALDNM 330

		               + +   +           DA    G     I     + N + KG      T  D  

		Sbjct: 295 NTLGQLALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDAS 354

		

		Query: 331 ALSFAD---AFNAVHEKGKTYTGEQGAAFFDFSGGEAV-----------PAKGAAAKIK- 375

		           A+   D   +F+    +               + G+             PA   +  +K 

		Sbjct: 355 AVLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKP 414

		

		Query: 376 VSDKI----LASTD--NIAASLNGEKSDGTNATNLAAVQN-SKLTINGETTTINDFYESL 428

		           VSD I    +  TD   IA +   +  D  N    A +   S     G   + ND Y SL

		Sbjct: 415 VSDAIVNMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASL 474

		

		Query: 429 IGKLGVNSQKAANLMNNSESNTLSADERRQSVSAVSLDEEMTNMIQFQHAYNAAARIITM 488

		           +  +G  +           +       ++QS+S V+LDEE  N+ +FQ  Y A A+++  

		Sbjct: 475 VSDIGNKTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQT 534

		

		Query: 489 QDEIFDKIIN 498

		            + IFD +IN

		Sbjct: 535 ANAIFDALIN 544

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 80.3 bits (198), Expect = 1e-19

		 Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 2/118 (1%)

		

		Query: 1   MTKVNIVIIDDHQLFREGVKRILDFEPTFEVVAEGDDGDEAARIVEHYHPDVVIMDINMP 60

		           MT   I++ DD    R  + + L     ++V    +      R +     D+V+ D+ MP

		Sbjct: 1   MTGATILVADDDAAIRTVLNQALSRAG-YDVRITSN-AATLWRWIAAGDGDLVVTDVVMP 58

		

		Query: 61  NVNGVEATKQLVELYPESKVIILSIHDDENYVTHALKTGARGYLLKEMDADTLIEAVK 118

		           + N  +   ++ +  P+  V+++S  +       A + GA  YL K  D   LI  + 

		Sbjct: 59  DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 41.8 bits (98), Expect = 3e-06

		 Identities = 30/179 (16%), Positives = 64/179 (35%), Gaps = 30/179 (16%)

		

		Query: 219 FQEIRNLRQNVRNALYEVRRIIYDL-----RPMALDDLGLIP------TLRKYLYTTE-E 266

		           F  + N+R  +     + R ++  L       +   +   +        +  YL     +

		Sbjct: 176 FNALNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQ 235

		

		Query: 267 YNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKH--SESEE---ITVKVEVT 321

		           +  +++   Q      + ++ P        L Q  V N +KH  ++  +   I +K    

		Sbjct: 236 FEDRLQFENQINPAIMDVQV-PPM------LVQTLVENGIKHGIAQLPQGGKILLKGTKD 288

		

		Query: 322 ADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLL---EGTITIDSKIGLGTFI 377

		              V L +++ G          K++   GL  ++ER+ +L   E  I +  K G    +

		Sbjct: 289 NGTVTLEVENTGSLALK---NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM 344

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 42.9 bits (101), Expect = 2e-06

		 Identities = 29/164 (17%), Positives = 65/164 (39%), Gaps = 4/164 (2%)

		

		Query: 26  GVISGAILFMKKELGLN---AFTEGLVVSSLLAGAILGSGFAGKLTDRFGRRKAIMGAAL 82

		           G+I   +  + ++L  +       G++++         +   G L+DRFGRR  ++ +  

		Sbjct: 22  GLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLA 81

		

		Query: 83  LFCIGGLGVAFAPNTEVMVLFRIILGLAVGTSTTIVPLYLSELAPKHKRGALSSLNQLMI 142

		              +    +A AP   V+ + RI+ G+  G +  +   Y++++    +R           

		Sbjct: 82  GAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMSACF 140

		

		Query: 143 TVGILVSYIVNYIFADAGAWRWMLGLAVVPSVILLIGILFMPES 186

		             G++   ++  +             A +  +  L G   +PES

		Sbjct: 141 GFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184

		

		

		

		 Score = 35.2 bits (81), Expect = 4e-04

		 Identities = 27/144 (18%), Positives = 58/144 (40%), Gaps = 7/144 (4%)

		

		Query: 32  ILFMKKELGLNAFTEGLVVSSL-LAGAILGSGFAGKLTDRFGRRKAIMGAALLFCIGGLG 90

		           ++F +     +A T G+ +++  +  ++  +   G +  R G R+A+M   +    G + 

		Sbjct: 234 VIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYIL 293

		

		Query: 91  VAFAPNTEVMVLFRIILGLAVGTSTTIVPLYLSELAPKHKRGALSSLNQLMITVG----- 145

		           +AFA     M    ++L  + G     +   LS    + ++G L      + ++      

		Sbjct: 294 LAFA-TRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGP 352

		

		Query: 146 ILVSYIVNYIFADAGAWRWMLGLA 169

		           +L + I          W W+ G A

		Sbjct: 353 LLFTAIYAASITTWNGWAWIAGAA 376

		

		

		>SSPAMPROTEIN#Salmonella surface presentation of antigen gene type M

		           signature.

		          Length = 147

		

		 Score = 29.3 bits (65), Expect = 0.007

		 Identities = 22/94 (23%), Positives = 48/94 (51%), Gaps = 8/94 (8%)

		

		Query: 24  KEETARASADEPVVIPDEAIRLRILANSDNDEDQKLKRQ-------IRDAVNKQITDWVK 76

		           ++E  R   +E  ++ ++   L++L ++   E+++L R+        +  V +QI D   

		Sbjct: 29  QDEDRRLQVEEEAIV-EQIAGLKLLLDTLRAENRQLSREEIYALLRKQSIVRRQIKDLEL 87

		

		Query: 77  DITTIEEARRLIRSKLPEIKEIAKQTMKEKGAHQ 110

		            I  I+E R  +  K  E +E +K  ++++G +Q

		Sbjct: 88  QIIQIQEKRSELEKKREEFQEKSKYWLRKEGNYQ 121

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 32.1 bits (73), Expect = 0.001

		 Identities = 16/83 (19%), Positives = 28/83 (33%)

		

		Query: 85  AEQRLAELERKLDILTKEKQGENHLLSRIEELERQLKQKADEGVSYQLLQHRREIDDLNT 144

		            E +  E   +L +   + +     +   +E  + + Q     +  +L Q    I  L  

		Sbjct: 257 QENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTL 316

		

		Query: 145 ELQTLASRIQELAQTAPLSETAA 167

		           EL     R Q     AP+S    

		Sbjct: 317 ELAKNEERQQASVIRAPVSVKVQ 339

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score =  110 bits (276), Expect = 9e-32

		 Identities = 32/121 (26%), Positives = 56/121 (46%)

		

		Query: 1   MMNEKILIVDDQYGIRILLNEVFHKEGYQTFQAANGIQALDIVTKERPDLVLLDMKIPGM 60

		           M    IL+ DD   IR +LN+   + GY     +N       +     DLV+ D+ +P  

		Sbjct: 1   MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60

		

		Query: 61  DGIEILKRMKMIDESIRVIIMTAYGELDMIKESKELGALTHFAKPFDIDEIRDAVKKYLP 120

		           +  ++L R+K     + V++M+A        ++ E GA  +  KPFD+ E+   + + L 

		Sbjct: 61  NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120

		

		Query: 121 L 121

		            

		Sbjct: 121 E 121

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score = 95.5 bits (237), Expect = 1e-25

		 Identities = 66/254 (25%), Positives = 113/254 (44%), Gaps = 7/254 (2%)

		

		Query: 4   RTAFIMGASQGIGKAIALKLADNGFHTVINSRVPENIESV--KEEILAKHPDAGVTVLAG 61

		           + AFI GA+QGIG+A+A  LA  G H       PE +E V    +  A+H +A       

		Sbjct: 9   KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEA----FPA 64

		

		Query: 62  DMSDQKTRAGIFEEIRSQCGRLDVLINNIPGGSPDTFENCDIEDMTNTFTNKTIAYIDSM 121

		           D+ D      I   I  + G +D+L+N      P    +   E+   TF+  +    ++ 

		Sbjct: 65  DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124

		

		Query: 122 KTAAAIMKQHEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKNIAIQLAPFHITVNC 181

		           ++ +  M     G I+ +  N    P  +M   +   AA +  +K + ++LA ++I  N 

		Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184

		

		Query: 182 LNPGFIATDRYHQFVKNVMKQNGISKAEAEERIASGVPMKRVGTAEETAALAAFLASEEA 241

		           ++PG   TD       +      + K   E    +G+P+K++    + A    FL S +A

		Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLET-FKTGIPLKKLAKPSDIADAVLFLVSGQA 243

		

		Query: 242 SYITGQQVSADGGS 255

		            +IT   +  DGG+

		Sbjct: 244 GHITMHNLCVDGGA 257

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score =  137 bits (347), Expect = 7e-42

		 Identities = 73/251 (29%), Positives = 118/251 (47%), Gaps = 6/251 (2%)

		

		Query: 6   KTVLITGGASGIGYAAVQAFLNQQANVVVADIDEAQGEAMIRKENNDRLHFVQ--TDITD 63

		           K   ITG A GIG A  +   +Q A++   D +  + E ++     +  H      D+ D

		Sbjct: 9   KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68

		

		Query: 64  EPACQNAIRSAADKFGGLDVLINNAGIEIVAPIHEMELSDWNKVLNVNLTGMFLMSKHAL 123

		             A          + G +D+L+N AG+     IH +   +W    +VN TG+F  S+   

		Sbjct: 69  SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128

		

		Query: 124 KYMLKSGKGNIINTCSVGGVVAWPDIPAYNASKGGVLQLTRSMAVDYAKHNIRVNCVCPG 183

		           KYM+    G+I+   S    V    + AY +SK   +  T+ + ++ A++NIR N V PG

		Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188

		

		Query: 184 IIDTPLNEKSFLENNEGTLEEIKKEKAKVN---PLLRLGKPEEIANVMLFLASDLSSYMT 240

		             +T +    + + N G  + IK          PL +L KP +IA+ +LFL S  + ++T

		Sbjct: 189 STETDMQWSLWADEN-GAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247

		

		Query: 241 GSAITADGGYT 251

		              +  DGG T

		Sbjct: 248 MHNLCVDGGAT 258

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 71.4 bits (175), Expect = 8e-16

		 Identities = 78/341 (22%), Positives = 128/341 (37%), Gaps = 19/341 (5%)

		

		Query: 28  LSLDMYLPALPEVAADLHTTASLAQLSLTFCLLGLAVGQIVVGP----LSDMIGRRKPLI 83

		           + + + +P LP +  DL  +  +         L  A+ Q    P    LSD  GRR  L+

		Sbjct: 19  VGIGLIMPVLPGLLRDLVHSNDVTAHYGILLAL-YALMQFACAPVLGALSDRFGRRPVLL 77

		

		Query: 84  LSLLLYTLSSLLCAFSPSVSFLIVMRFIQGFTGAAGIVIARASARDMYSGKELTAFFSLL 143

		           +SL    +   + A +P +  L + R + G TGA G V     A D+  G E    F  +

		Sbjct: 78  VSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIA-DITDGDERARHFGFM 136

		

		Query: 144 MLVNGAAPILAPITGGFILQFAGWKIVFVVLAVIGCIISAAVLTALPESLPPEKRTSGGL 203

		               G   +  P+ GG +  F      F   A +  +        LPES   E+R     

		Sbjct: 137 SACFGFGMVAGPVLGGLMGGF-SPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLR-- 193

		

		Query: 204 RETLMTFRGLLGDRMFMGFALSQA-FVMTGMFAYIAGSPFVL--QNIYGVSAQMFSLLFA 260

		           RE L         R     A   A F +  +   +  + +V+  ++ +   A    +  A

		Sbjct: 194 REALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLA 253

		

		Query: 261 VNGA-GIICATQITGRMAKTHDERKLFVSGLLIAVIGSIALLLSLAFGSGLTAVCISLFI 319

		             G    +    ITG +A    ER+  + G++    G    +L      G  A  I + +

		Sbjct: 254 AFGILHSLAQAMITGPVAARLGERRALMLGMIADGTG---YILLAFATRGWMAFPIMVLL 310

		

		Query: 320 IVSSVGIVTTTGF---SLAMQKQEKGAGSAAALLGLLPFIG 357

		               +G+          +  ++Q +  GS AAL  L   +G

		Sbjct: 311 ASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVG 351

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score = 69.0 bits (169), Expect = 1e-15

		 Identities = 56/239 (23%), Positives = 92/239 (38%), Gaps = 44/239 (18%)

		

		Query: 3   KVLVTGAAGQLGRELCRQLKREGYEVIAL------------------------TKAMMNI 38

		           K LVTGAAG +G  + ++L   G++V+ +                            +++

		Sbjct: 2   KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61

		

		Query: 39  SDQRSVRHSFSHYKPDIVVNTAAYTSVDKCETELDKAYLINGIGAYYAALEA--ENTGAK 96

		           +D+  +   F+    + V  +    +V +   E   AY  + +  +   LE    N    

		Sbjct: 62  ADREGMTDLFASGHFERVFISPHRLAV-RYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120

		

		Query: 97  FIHISTDYVFSGKGTRPYQTDDPAD-PGTIYGKSKKLGEELI----RLTGKNHTIIRTSW 151

		            ++ S+  V+      P+ TDD  D P ++Y  +KK  E +      L G   T +R   

		Sbjct: 121 LLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFT 180

		

		Query: 152 VYGSGG------HNFVNTMLKLADTHDQVRVVNDQVGAP--TYTKDLAETVIGLFDRPP 202

		           VYG  G        F   ML+       + V N        TY  D+AE +I L D  P

		Sbjct: 181 VYGPWGRPDMALFKFTKAMLE----GKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIP 235

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score =  166 bits (423), Expect = 2e-51

		 Identities = 77/332 (23%), Positives = 146/332 (43%), Gaps = 26/332 (7%)

		

		Query: 4   SYLITGGAGFIGLTFTKMMLKETDAQITVLDNLT--Y--ASRPLEIEALKKNGRFRFIKG 59

		            YL+TG AGFIG   +K +L+    Q+  +DNL   Y  + +   +E L + G F+F K 

		Sbjct: 2   KYLVTGAAGFIGFHVSKRLLEAGH-QVVGIDNLNDYYDVSLKQARLELLAQPG-FQFHKI 59

		

		Query: 60  DISEKEDIDKVF-SQMYDAVIHFAAESHVDRSINQAEPFITTNVMGTYRLADAVLQGKAG 118

		           D++++E +  +F S  ++ V        V  S+     +  +N+ G   + +     K  

		Sbjct: 60  DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119

		

		Query: 119 RLIHISTDEVYGDLAPDDPAFTETTPLSPNNPYSASKASSDLLVMSYVRTHKLPAIITRC 178

		            L++ S+  VYG L    P  T+ +   P + Y+A+K +++L+  +Y   + LPA   R 

		Sbjct: 120 HLLYASSSSVYG-LNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRF 178

		

		Query: 179 SNNYGPYQHHEKMIPTIIRHAVNGTPVPLYGDGMQIRDWLFAEDHCRAIKLVLEKGTLGD 238

		              YGP+   +  +    +  + G  + +Y  G   RD+ + +D   AI  + +     D

		Sbjct: 179 FTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHAD 238

		

		Query: 239 ------------------IYNIGGGNERTNKELASFIMKELGVEERFAHVEDRKGHDRRY 280

		                             +YNIG  +     +    +   LG+E +   +  + G     

		Sbjct: 239 TQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDVLET 298

		

		Query: 281 AINASKLKNELGWRQDVTFEEGMRRTIRWYTD 312

		           + +   L   +G+  + T ++G++  + WY D

		Sbjct: 299 SADTKALYEVIGFTPETTVKDGVKNFVNWYRD 330

		

		

		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

		          Length = 173

		

		 Score = 37.2 bits (86), Expect = 3e-05

		 Identities = 23/117 (19%), Positives = 44/117 (37%), Gaps = 8/117 (6%)

		

		Query: 156 FTKSRYYQDPHL-SYESANRLFEEWARNNAEGRASLQFAATYKGETVGFVQGLSKGDEF- 213

		           +T+ R+   P+   YE  +              A L +    +   +G ++  S  + + 

		Sbjct: 37  YTEERF-SKPYFKQYEDDDMDVSY--VEEEGKAAFLYYL---ENNCIGRIKIRSNWNGYA 90

		

		Query: 214 VLDLMAVKPGFEGKGAGFHLAAHVIEQSLRFQHKTVSAGTQLHNVRAIRLYERMGFK 270

		           +++ +AV   +  KG G  L    IE +       +   TQ  N+ A   Y +  F 

		Sbjct: 91  LIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score = 27.9 bits (62), Expect = 0.036

		 Identities = 23/146 (15%), Positives = 47/146 (32%), Gaps = 5/146 (3%)

		

		Query: 38  HLEKGKTESEAMALILREVGTPSEIISAFQKASAVPARTF--MLFYLFCNCGLFVMGAM- 94

		            +E      EA    + ++      I+    A  +P   F      ++    + ++ AM 

		Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479

		

		Query: 95  ITMMHAWRIHPAVDALWKGISVSVWLIMIGYVLYWFQIGYQAGKEFGAGG--KKLAERTV 152

		           ++++ A  + PA+ A       +      G    WF   +            K L     

		Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539

		

		Query: 153 WASMAPNLCFMFVFLFNLVPAGLFPS 178

		           +  +   +    V LF  +P+   P 

		Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPE 565

		

		

		>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature.

		          Length = 428

		

		 Score = 28.0 bits (62), Expect = 0.031

		 Identities = 18/70 (25%), Positives = 28/70 (40%), Gaps = 9/70 (12%)

		

		Query: 139 EIPVYLTNRVEYVKAEIQIRTIAMDFWASLEHKIYYKLNNEVPKHLTDELKEAADIAHYL 198

		            I  Y+    E ++   QI+ I +DF    E+K +Y L   +        KE+A    Y 

		Sbjct: 131 SIKQYIDAHREELE-RNQIKIIGIDFDIETEYKWFYSLQFNI--------KESAFTTGYA 181

		

		Query: 199 DEKMLGIKKE 208

		               L  + E

		Sbjct: 182 IASWLSEQDE 191

		

		

		>PF05043#Transcriptional activator

		          Length = 493

		

		 Score = 42.6 bits (100), Expect = 3e-06

		 Identities = 35/233 (15%), Positives = 85/233 (36%), Gaps = 32/233 (13%)

		

		Query: 8   ELLRLLLAAETPVTSSVIAANVKVTTRTVRNDIKELQTIVEKHGASIQSVRGSGYKLLIR 67

		           ELL LL   +     S +A  +  T R V++D+  +++        +     +    +I 

		Sbjct: 14  ELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAF----PDLIFHSSTNGIRIIN 69

		

		Query: 68  NEQPFKNWLQDNFQQNSTVPIFPDERIDYLMKRMLLADGYLKLDDLAEELFISKSTLQSD 127

		            +      +  +F ++ST          + +   +  +   + + + +E +IS S+L   

		Sbjct: 70  TDDSDIEMVYHHFFKHSTH---------FSILEFIFFNEGCQAESICKEFYISSSSLYRI 120

		

		Query: 128 LKEVKKRLR-PYDIILETRPNYGFKLRGEELRLRYCMAEYLVDDREPEPDLLSEKAGI-- 184

		           + ++ K ++  +   +   P    ++ G E  +RY  A+Y            SEK     

		Sbjct: 121 ISQINKVIKRQFQFEVSLTPV---QIIGNERDIRYFFAQY-----------FSEKYYFLE 166

		

		Query: 185 --LPKDDIHVIRTAIMKQVRNHKIPLSFFGLNNLIIHIAIACKRIRTENYVSL 235

		                     +   +    +    P++      L + +     RI+  +++ +

		Sbjct: 167 WPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEV 219

		

		

		>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature.

		          Length = 296

		

		 Score = 63.0 bits (153), Expect = 1e-13

		 Identities = 51/258 (19%), Positives = 99/258 (38%), Gaps = 35/258 (13%)

		

		Query: 36  KIASMSIHLTNDLLALGVTPAG--SVVGGELKDFLPHVKNQLKDTKKLGPASDPDMEALL 93

		           +I ++       LLALG+ P G    +   L    P + + + D   +G  ++P++E L 

		Sbjct: 37  RIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVID---VGLRTEPNLELLT 93

		

		Query: 94  ELNPDNIYLDKEFAGKDVSKYKKIGNTHVFDLDKGT-----WRDHLKDIGKIVNREKEAK 148

		           E+ P    +     G       +I     F+   G       R  L ++  ++N +  A+

		Sbjct: 94  EMKPS-FMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAE 152

		

		Query: 149 TFIQDYEDETKQVRSMMNKELGKNAK--VMAIRVNAKELRVFSTRRPMGPILFDDLKLKP 206

		           T +  YED    +RSM  + + + A+  ++   ++ + + VF         LF +  +  

		Sbjct: 153 THLAQYED---FIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGP-----NSLFQE--ILD 202

		

		Query: 207 ADGIKEMNTSRP----YEVISQEVLPDY-NADAI-FVVVNRDDKSQQAYKELQKSAVWKG 260

		             GI               +S + L  Y + D + F   N  D        L  + +W+ 

		Sbjct: 203 EYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDA-----LMATPLWQA 257

		

		Query: 261 LKAVKANHVYKIADQPWL 278

		           +  V+A    ++    W 

		Sbjct: 258 MPFVRAGRFQRVPAV-WF 274

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score = 32.9 bits (75), Expect = 0.004

		 Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 2/38 (5%)

		

		Query: 137 MAIVPAAVVIYVFFQDKTSALILILALP--ILIVFMIL 172

		            AI+   +V+Y+F Q+  + LI  +A+P  +L  F IL

		Sbjct: 346 EAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAIL 383

		

		

		>UREASE#Urea amidohydrolase (urease) protein signature.

		          Length = 570

		

		 Score = 34.7 bits (80), Expect = 6e-04

		 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 8/52 (15%)

		

		Query: 358 TVNAAYAIGKGEEAGQIKAGRAADIVIWEAPNYMYIPYHYGVNHVHCVIKNG 409

		           T+N A A G   E G ++ G+ AD+V+W        P  +GV     V+  G

		Sbjct: 410 TINPAIAHGLSHEIGSLEVGKRADLVLWN-------PAFFGVK-PDMVLLGG 453

		

		

		

		 Score = 33.2 bits (76), Expect = 0.002

		 Identities = 29/110 (26%), Positives = 43/110 (39%), Gaps = 20/110 (18%)

		

		Query: 38  AVIGISDGRIVFAGHQGAEEGYE--------ARDIIDCGGRLVTPGLVDPHTHLVFGGSR 89

		           A IG+ DGRI   G  G  +             ++I   G++VT G +D H H +     

		Sbjct: 86  ADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFICPQQI 145

		

		Query: 90  EKELNLKIQGMSYLDILAQGGGILSTVKDTKAASEEELIEKGLFHLGRML 139

		           E+ L   +  M        GGG       T A +       G +H+ RM+

		Sbjct: 146 EEALMSGLTCML-------GGGT-GPAHGTLATT----CTPGPWHIARMI 183

		

		

		>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature.

		          Length = 296

		

		 Score = 55.7 bits (134), Expect = 4e-11

		 Identities = 46/247 (18%), Positives = 93/247 (37%), Gaps = 34/247 (13%)

		

		Query: 55  PKRIVTD--FYAGELLSVD------ANVVGAGSWAFKNPFIKKQLKNTTDIG--NPVNVE 104

		           P RIV         LL++       A+ +    W  + P       +  D+G     N+E

		Sbjct: 35  PNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPD----SVIDVGLRTEPNLE 90

		

		Query: 105 KVMQLKPDLIVLMK--DDQYEKLSKIAPTIVIPFNTAKN----TKDTVSLFGDIAGAKDK 158

		            + ++KP  +V         E L++IAP     F+  K      + +++   D+   +  

		Sbjct: 91  LLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSA 150

		

		Query: 159 AKSFMADFNKKAEANQKRLKNVIGKDET-VGLYETTDKGEIWIFNDNSGRGGQAVYNALG 217

		           A++ +A +     + + R    + +    + L    D   + +F  NS    Q + +  G

		Sbjct: 151 AETHLAQYEDFIRSMKPRF---VKRGARPLLLTTLIDPRHMLVFGPNS--LFQEILDEYG 205

		

		Query: 218 LKAPAKIEKDIMKTGAMKQVSQEVIPQYA-ADYMFITDYNPNGESKTFERLKDSSVWKNL 276

		           +    + E +   + A   VS + +  Y   D +     N     K  + L  + +W+ +

		Sbjct: 206 IPNAWQGETNFWGSTA---VSIDRLAAYKDVDVLCFDHDNS----KDMDALMATPLWQAM 258

		

		Query: 277 DAVKNNR 283

		             V+  R

		Sbjct: 259 PFVRAGR 265

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 40.6 bits (95), Expect = 5e-06

		 Identities = 58/344 (16%), Positives = 118/344 (34%), Gaps = 67/344 (19%)

		

		Query: 4   FLRSHAVLILLFLLQGLFVFFYYWFAGLHSFSHLFYILGVQLLILAGYL-AYRWYKDRG- 61

		            L S    I + L+  +    Y  F     +  L     +  ++ A  +    W+     

		Sbjct: 38  KLHSMIFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQIILRVLPACVVIGMVWFVANTS 97

		

		Query: 62  ---VYHWLSWEQEGTDIPYLGSSVFCSEL-------------YEKQMELIRMQHQKL--H 103

		              +  +++ +     +P   S +F   +             + K  +   +   K+   

		Sbjct: 98  IWRLLAFINTKPVAFTLPLALSIIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASM 157

		

		Query: 104 ETEAKLDARVTYMNQWVHQVKTPLSVINLIIQEEDEPVFEQIKKEVRQIEFGLETLL-YS 162

		             EA+L A    +N   H +   L+ I  +I E+          + R++   L  L+ YS

		Sbjct: 158 AQEAQLMALKAQINP--HFMFNALNNIRALILEDPT--------KAREMLTSLSELMRYS 207

		

		Query: 163 SRLDLFERDFKVEAVSLSELLQSVIQSYKRFFIQYRVYP---KMDIRDDHQIYTDAKWLK 219

		            R            VSL++ L +V+ SY    +    +    + + + +  I  D +   

		Sbjct: 208 LRYS------NARQVSLADEL-TVVDSY--LQLASIQFEDRLQFENQINPAIM-DVQVPP 257

		

		Query: 220 FAIGQVVTNAVKYSAGKSD---RLELNVFRDEDRTVLEVKDYGVGIPSQDIKRVFDPYYT 276

		             +  +V N +K+   +     ++ L   +D     LEV++ G                 

		Sbjct: 258 MLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNT---------- 307

		

		Query: 277 GENGRRFQESTGIGLHLVKE---ITGKLNHTVDISSSPGEGTSV 317

		                  +ESTG GL  V+E   +       + +S   G+  ++

		Sbjct: 308 -------KESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM 344

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 78.3 bits (193), Expect = 5e-19

		 Identities = 38/175 (21%), Positives = 74/175 (42%), Gaps = 7/175 (4%)

		

		Query: 3   KIMIVEDSEDIRGLLQNYLEKYGYQTVAAADFTAVLDVFLREKADVVLLDINLPSYDGYY 62

		            I++ +D   IR +L   L + GY     ++   +         D+V+ D+ +P  + + 

		Sbjct: 5   TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64

		

		Query: 63  WCRQIRQHSTS-PIIFISARSGEMDQVMAIENGGDDYIEKPFSYDIVLAKIKSQIRRAYG 121

		              +I++     P++ +SA++  M  + A E G  DY+ KPF    ++      I RA  

		Sbjct: 65  LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIG----IIGRALA 120

		

		Query: 122 EYAAKQGEKVVEYAGVQLFVERFELRFQDEKSELSKKESKLLEVLLERGEKVTGR 176

		           E   +  +   +       V R     Q+    L++     L +++  GE  TG+

		Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGR-SAAMQEIYRVLARLMQTDLTLMI-TGESGTGK 173

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 54.4 bits (131), Expect = 3e-10

		 Identities = 73/317 (23%), Positives = 111/317 (35%), Gaps = 16/317 (5%)

		

		Query: 42  LKLSDSQIGLLGAF-SANAISAAIGALLGGYLADKVGRKAVYTNSMLVYALGICLVLFGF 100

		           L  S+      G   +  A+     A + G L+D+ GR+ V   S+   A+   ++    

		Sbjct: 35  LVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAP 94

		

		Query: 101 NFPMLLCGYMIIGISVGADITASWTIIAENAPEKNRARHCGVAQVAWAAGAVVVLLLSVL 160

		              +L  G ++ GI+ GA    +   IA+      RARH G     +  G V   +L  L

		Sbjct: 95  FLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGL 153

		

		Query: 161 VGDLGLLGNKIVFAHLLVIALITYVIRKRLPESDAWKNSEDRPAAVKKTSYFDLLQPKFF 220

		           +G           A L  +  +T      LPES      E RP   +  +     +    

		Sbjct: 154 MGGFSPHAPFFAAAALNGLNFLTGCF--LLPES---HKGERRPLRREALNPLASFRWARG 208

		

		Query: 221 KNIL-FLMGVFLVWNLAAGVMGFFMPYIYQQVGGVSANTANILQMALFIFTGLGVACIFM 279

		             ++  LM VF +  L   V         +      A T  I   A  I   L  A I  

		Sbjct: 209 MTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITG 268

		

		Query: 280 PFADKYRKTVFGICACMAVVGWSLFLLPFQG---LPMLLLFVLAIGINNGAGQQANYQLW 336

		           P A +  +    +   M   G    LL F     +   ++ +LA G   G G  A  Q  

		Sbjct: 269 PVAARLGERRA-LMLGMIADGTGYILLAFATRGWMAFPIMVLLASG---GIGMPA-LQAM 323

		

		Query: 337 ASELFPTEHRASAQGLM 353

		            S     E +   QG +

		Sbjct: 324 LSRQVDEERQGQLQGSL 340

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 42.1 bits (99), Expect = 3e-06

		 Identities = 80/427 (18%), Positives = 154/427 (36%), Gaps = 56/427 (13%)

		

		Query: 1   MKKNTKKYLIYFFGALGGLLYGYDTGVISGAL--LFINNDIPLNTLTEGLVVSMLLLGAI 58

		           MK N    +I    AL  +  G    V+ G L  L  +ND+  +    G+++++  L   

		Sbjct: 1   MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHY---GILLALYALMQF 57

		

		Query: 59  FGSALSGTCSDRWGRRKVVFVLSLIFIIGALACAASQTVTMLIISRVILGLAVGGSTALV 118

		             + + G  SDR+GRR V+ V      +     A +  + +L I R++ G+  G + A+ 

		Sbjct: 58  ACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVA 116

		

		Query: 119 PVYLSEMAPTKIRGTLGTLNNLMIVTGILLAYIVNYIFTPFEAWRWMVGLAAVPAALLLI 178

		             Y++++     R       +     G++   ++  +   F         AA+     L 

		Sbjct: 117 GAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLT 176

		

		Query: 179 GIAFMPESPRWLVKRGREQEARQVMEMTHDKEDIAVELAEMKQGEAEKKESTLGLLKAKW 238

		           G   +PES      +G  +  R+                               L   +W

		Sbjct: 177 GCFLLPES-----HKGERRPLRREALNP--------------------------LASFRW 205

		

		Query: 239 IRPMLLIGIGLAIFQQAVGINTVIYYAPTIFTKAGLGTSASVLGTM--GIGVLNVIMCIT 296

		            R M ++   +A+F     +  V      IF +      A+ +G      G+L+ +    

		Sbjct: 206 ARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAM 265

		

		Query: 297 AM-ILIDRIGRKKLLMWGSVGITLSLASLSAILLLAGLSASTAWLTVLFLGIYIVFYQAT 355

		               +  R+G ++ LM G     +       ILL        A+  ++ L    +     

		Sbjct: 266 ITGPVAARLGERRALMLG-----MIADGTGYILLAFATRGWMAFPIMVLLASGGIGM--- 317

		

		Query: 356 WGPVVWVLMPELFPSNARGAATGFTTLILSATNLIVSLVFPLMLSAM-----GIGWVFG- 409

		             P +  ++        +G   G    + S T+++  L+F  + +A      G  W+ G 

		Sbjct: 318 --PALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGA 375

		

		Query: 410 IFSVICL 416

		              ++CL

		Sbjct: 376 ALYLLCL 382

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score =  131 bits (330), Expect = 5e-39

		 Identities = 77/249 (30%), Positives = 123/249 (49%), Gaps = 4/249 (1%)

		

		Query: 7   KTAIITGAATGIGQATARVFADEGARVICGDINESELNETVSAIRKNGGEAEAFHLDVSD 66

		           K A ITGAA GIG+A AR  A +GA +   D N  +L + VS+++     AEAF  DV D

		Sbjct: 9   KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68

		

		Query: 67  EENVKSFADGIQQKYETIDILFNNAGVDQEGGKVHEYPVDLFDRIIAVDLRGTFLCSKYL 126

		              +      I+++   IDIL N AGV +  G +H    + ++   +V+  G F  S+ +

		Sbjct: 69  SAAIDEITARIEREMGPIDILVNVAGVLRP-GLIHSLSDEEWEATFSVNSTGVFNASRSV 127

		

		Query: 127 IPLML-EKGGSIINTSSMSGRAADLDRSGYNAAKGGITNLTRAMAIDYARSGIRVNSLSP 185

		              M+  + GSI+   S          + Y ++K      T+ + ++ A   IR N +SP

		Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187

		

		Query: 186 GTIETPLIDKL--AGTTEDEMGEAFREANKWITPLGRLGKPEEMAAVALFLASDDSSYVT 243

		           G+ ET +   L       +++ +   E  K   PL +L KP ++A   LFL S  + ++T

		Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247

		

		Query: 244 GEDITADGG 252

		             ++  DGG

		Sbjct: 248 MHNLCVDGG 256

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 55.6 bits (134), Expect = 2e-11

		 Identities = 22/152 (14%), Positives = 57/152 (37%), Gaps = 8/152 (5%)

		

		Query: 4   IFIAEDQQMLLGALGSLLNLE-EDMTVVGQGTSGQDAIDFVEKHAPDICLMDIEMPGKSG 62

		           I +A+D   +   L   L+    D+ +     +      ++     D+ + D+ MP ++ 

		Sbjct: 6   ILVADDDAAIRTVLNQALSRAGYDVRITS---NAATLWRWIAAGDGDLVVTDVVMPDENA 62

		

		Query: 63  LEAAEELK--DSGVKIIILTTFARSGYFQRALKAGVSGYMLKDSPSDELVSAIRSVMKGR 120

		            +    +K     + +++++         +A + G   Y+ K     EL+  I   +   

		Sbjct: 63  FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122

		

		Query: 121 RVYAPELMEDIYSEENPLTERE--KEVLELVA 150

		           +    +L +D       +      +E+  ++A

		Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLA 154

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 57.6 bits (139), Expect = 2e-11

		 Identities = 84/385 (21%), Positives = 142/385 (36%), Gaps = 65/385 (16%)

		

		Query: 2   KKYFKFQKLNGISPYIWMIFFILPFYFIFKSSSTFVIVAGIIFTLVFFGAYRFAFVAKGW 61

		            KY+ + +  G   Y    F     Y   K  S    +A  +  LV   AYR     +GW

		Sbjct: 9   NKYYWYCQGIGWGVYTLTGFGFASLYGSPKLHSMIFNIAISLMGLVLTHAYRSFIKRQGW 68

		

		Query: 62  PLYLWALLLIGISTGSAMLFSYIYFAFFIAY-----FIGHIRDKVPFYILYYIHIISAAV 116

		            L L    +I     + ++   ++F    +      FI      V F +   + II   V

		Sbjct: 69  -LKLNMGQIILRVLPACVVIGMVWFVANTSIWRLLAFINT--KPVAFTLPLALSIIFNVV 125

		

		Query: 117 AVNFSLVLKKEWFLTQIPFIVITLISAILLPLSIRSRKARERLEEKLEYANERIADLVKL 176

		            V F                     S +           +  +++    +  + A L+ L

		Sbjct: 126 VVTFMW-------------------SLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMAL 166

		

		Query: 177 EERQRIARD-LHDTLGQKLSLIGLKSDLARKLIYKDPEQARTELKSVQQTARTSLNEVRK 235

		             + +I    + + L           +  R LI +DP +AR  L S+ +  R SL     

		Sbjct: 167 --KAQINPHFMFNAL-----------NNIRALILEDPTKAREMLTSLSELMRYSLRY--- 210

		

		Query: 236 IVSSMKGIRLKDELGNVRQILEAAGIEF----VYEEKEAPKHISLLNENIVSMCIKEAVT 291

		             S+ + + L DEL  V   L+ A I+F     +E +  P   ++++  +  M ++  V 

		Sbjct: 211 --SNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINP---AIMDVQVPPMLVQTLVE 265

		

		Query: 292 NVVKH------SGAKVCRITIQQLWKEVVITVEDDGSFQCKEDRFFSKGHGLLGMRERLE 345

		           N +KH       G K+  +   +    V + VE+ GS   K  +  S G GL  +RERL+

		Sbjct: 266 NGIKHGIAQLPQGGKI-LLKGTKDNGTVTLEVENTGSLALKNTK-ESTGTGLQNVRERLQ 323

		

		Query: 346 FANG---SLAIDTAAG-TKLTMRIP 366

		              G    + +    G     + IP

		Sbjct: 324 MLYGTEAQIKLSEKQGKVNAMVLIP 348

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 54.2 bits (130), Expect = 1e-10

		 Identities = 16/111 (14%), Positives = 43/111 (38%), Gaps = 3/111 (2%)

		

		Query: 198 KPADRRVTRTRQALQEAMIGLMAEKKEYAAITISDIARQSNLRRATFYDHYANKEALLKT 257

		           +   +    TRQ + +  + L +++   ++ ++ +IA+ + + R   Y H+ +K  L   

		Sbjct: 3   RKTKQEAQETRQHILDVALRLFSQQG-VSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61

		

		Query: 258 IIHQSCRDLIGLL-TVKGEPADCSMEEAEAALVRLFSALSDGLPLVHFMRE 307

		           I   S  ++  L    + +     +      L+ +  +          + E

		Sbjct: 62  IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTE-ERRRLLME 111

		

		

		

		 Score = 46.5 bits (110), Expect = 5e-08

		 Identities = 14/59 (23%), Positives = 31/59 (52%)

		

		Query: 9  IKQALLAMLGERDIRRVTMKDIAERARVSRGTLYLYYEDKYAILEDIEEEMKDGLSEAL 67

		          I    L +  ++ +   ++ +IA+ A V+RG +Y +++DK  +  +I E  +  + E  

		Sbjct: 16 ILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELE 74