>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 30.2 bits (68), Expect = 0.045 Identities = 19/83 (22%), Positives = 39/83 (46%), Gaps = 14/83 (16%) Query: 549 SREVTKTSVWALGSSLVGIVVALGLSMGMDRVAGGFFEF---FGSVGMLIHLAIVGVVFL 605 S E+ T+VW+L ++ V I+ + + FE+ G+V L+H ++ V Sbjct: 148 SGELVWTAVWSLLAATVVIMFYIWVR----------FEWQFALGAVVALVHDVLLTVGLF 197 Query: 606 VVTALVLSRSGLEEVVS-LGYAL 627 V L + + +++ GY++ Sbjct: 198 AVLQLKFDLTTVAALLTITGYSI 220
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 34.3 bits (79), Expect = 4e-04 Identities = 30/116 (25%), Positives = 43/116 (37%), Gaps = 13/116 (11%) Query: 122 GVDSILLPDVPVREGEPFIAAAKQAGIDPI--FIAPAQASEATLEGVAQHSSGYIYAISR 179 GV I+ P V GE I A G+D FI P Q EA + G+ G Sbjct: 109 GVTIIVGPGTEVIAGEGKIVTA--GGMDSHIHFICPQQIEEALMSGLTCMLGGGTGP--- 163 Query: 180 DGVTGTERQSSTRGLDKVVANVKRFGGAPILLGF----GISTPEHVRDAIAAGASG 231 GT + T G + ++ P+ L F S P + + + GA+ Sbjct: 164 --AHGTLATTCTPGPWHIARMIEAADAFPMNLAFAGKGNASLPGALVEMVLGGATS 217
>PF06776#Invasion associated locus B Length = 214 Score = 33.4 bits (76), Expect = 0.001 Identities = 13/58 (22%), Positives = 20/58 (34%), Gaps = 8/58 (13%) Query: 4 PSISSSVRRACATATAVIALAGVAAPS-ANAQSSNPIEAGSSALNYGANSLLAEWSKN 60 P ++S R A A + LAG A + + S G+ +G W Sbjct: 36 PMLASCRRLARRN-GARLMLAGAMAIALSFGWSDRADAQGAVRSVHGD------WQIR 86
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 30.4 bits (68), Expect = 0.009 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (4%) Query: 234 AHSENQAPRVEKEETTLAKITKNAPTIAHALEL---KPEQSFEELLRTTGLSQGQLRFAL 290 AH+ N A + E E LAK + A A A E + EQ +E+ R ++ QL+ A Sbjct: 116 AHANNAAMQAEDERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQLKLAE 175 Query: 291 DKLQ 294 + + Sbjct: 176 AEEK 179
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 116 bits (291), Expect = 6e-36 Identities = 33/145 (22%), Positives = 69/145 (47%), Gaps = 2/145 (1%) Query: 13 DAKQLIDHLQERLTDYNDLHLILKHAHWNVHGRNFIAVHEMIDPQVDLVRGYADEVAERI 72 + + + L +L+++ L+ L HW V G +F +HE + D D +AER+ Sbjct: 9 NQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIAERL 68 Query: 73 ATLGGTPIGTPVGHVENRTPLEYNVNSGSTEDHLKELNKVYTKVLEGVREAMANAGD-LD 131 +GG P+ T + E+ + + + S + ++ L Y ++ + + A + D Sbjct: 69 LAIGGQPVATVKEYTEHASITDGGNET-SASEMVQALVNDYKQISSESKFVIGLAEENQD 127 Query: 132 SVTEDIYIGQAAELEKFQWFIREHI 156 + T D+++G E+EK W + ++ Sbjct: 128 NATADLFVGLIEEVEKQVWMLSSYL 152
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 68.9 bits (168), Expect = 3e-16 Identities = 47/190 (24%), Positives = 73/190 (38%), Gaps = 13/190 (6%) Query: 3 RVAVVTGGSRGVGLSVVRTLLEAGWRVHAHYRTQPADITHDRLTWWQADFTQGLPTAQAS 62 ++A +TG ++G+G +V RTL G + A +A + P Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 63 G----------FPQLPRIDALIHCAGVATLGSCASVERDEWERHMSVNLHSPVQLTRQLL 112 ++ ID L++ AGV G S+ +EWE SVN +R + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 113 PQLRANHA-HVVYINSGAGKRANPQWGAYAASKFAAR--AWCDALRQEEPEITVTSIFPG 169 + + +V + S AYA+SK AA C L E I + PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 170 RIATDMQKAI 179 TDMQ ++ Sbjct: 189 STETDMQWSL 198
>cloacin#Cloacin signature. Length = 551 Score = 33.9 bits (77), Expect = 3e-04 Identities = 26/61 (42%), Positives = 30/61 (49%), Gaps = 4/61 (6%) Query: 127 NGGGNFGGSQGGFGGNTGGNSGGGFGAPQGGFGGGPQNSQSAAPA--NDPWSSAPQAGGF 184 GGG+ GS +GG +G +GGG G GG G G S AAP P S P AGG Sbjct: 46 WGGGS--GSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGL 103 Query: 185 G 185 Sbjct: 104 A 104 Score = 30.1 bits (67), Expect = 0.006 Identities = 11/35 (31%), Positives = 16/35 (45%) Query: 127 NGGGNFGGSQGGFGGNTGGNSGGGFGAPQGGFGGG 161 + GN G G G G + G G+ + +GGG Sbjct: 15 STSGNINGGPTGLGVGGGASDGSGWSSENNPWGGG 49 Score = 27.4 bits (60), Expect = 0.038 Identities = 19/62 (30%), Positives = 23/62 (37%), Gaps = 3/62 (4%) Query: 125 GGNGGGNFGGSQGGFGGNTGGNSGGGFGAPQGGFGGGPQNSQSAAPANDPWSSAPQAGGF 184 GG+G G+ G+ G GG +G G GG G S P S GG Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLG---VGGGASDGSGWSSENNPWGGGSGSGIHWGGG 59 Query: 185 GG 186 G Sbjct: 60 SG 61
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 54.8 bits (132), Expect = 3e-10 Identities = 80/380 (21%), Positives = 135/380 (35%), Gaps = 41/380 (10%) Query: 37 ALDAMDVGLISFVMAALIKHWGLTHGQTS---VLASAGFVGMAIGATFGGLLADKWGRRN 93 ALDA+ +GLI V+ L++ ++ T+ +L + + A G L+D++GRR Sbjct: 15 ALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRP 74 Query: 94 VFALTLLVYGLATGASALAGGLAVLIVLRFIVGLGLGAELPVASTLVSEFAPLRHRGRLV 153 V ++L + A A L VL + R + G+ GA VA +++ R R Sbjct: 75 VLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARHF 133 Query: 154 VILEAFWAVGWILAAIIGAFVVSAS-DSGWRWALVLGCVPALYSAYVRSSLPESVRFLEA 212 + A + G + ++G + S + + A L + L ++ LPES + Sbjct: 134 GFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFL---LPESHK---- 186 Query: 213 RGRHDEAEAAVQQFEKASATIPDTPVIATEDPADQADSIFAPNMRRRTFGLWTVWFCINL 272 R A+ T V A L V+F + L Sbjct: 187 GERRPLRREALNPLASFRWARGMTVVAA----------------------LMAVFFIMQL 224 Query: 273 -SYYGAFIWIPSLLVADGF---SLVKSFQFTLIITLAQFPGYALAAWLIEIWGRRTTLAV 328 A +W + D F + L + + G R L + Sbjct: 225 VGQVPAALW--VIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALML 282 Query: 329 FLLGSAGSAALYGFADTTALIIAAGCCLSFFNLGAWGALYAISPELYPSQIRGTGTGSAA 388 ++ L FA + L+ +G AL A+ + +G GS A Sbjct: 283 GMIADGTGYILLAFATRGWMAFPIMVLLASGGIGM-PALQAMLSRQVDEERQGQLQGSLA 341 Query: 389 GFGRIASIIAPLIVPPIVAA 408 + SI+ PL+ I AA Sbjct: 342 ALTSLTSIVGPLLFTAIYAA 361
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 46.6 bits (110), Expect = 2e-07 Identities = 47/268 (17%), Positives = 70/268 (26%), Gaps = 44/268 (16%) Query: 192 PDEEGEEGEFPAAAAEATAAAAEAAADTTVTTDATDNEATPPVPTPEQVAEKSQREAPAA 251 DE PA +E T AE + + T + + +AT +VA++++ A Sbjct: 1020 VDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKAN 1079 Query: 252 P---------------------IPCPQRPGEPALSEEDCMAEVPAKMPK--PVAPKPGAH 288 E A E + EVP + P + Sbjct: 1080 TQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETV 1139 Query: 289 LPAETPAPAPTATPAPTPSSRTVRVTSTVEESLEVTVSNSAEPNVEAEEADTPATPRPAP 348 P PA T T+ E+ + T SN +P E Sbjct: 1140 QPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQP--VTESTTVNTGNSVVE 1197 Query: 349 NP-----SMMAPRRKLRSRYVP-----------LPNEVWASAGYQTPFDVGQQYALWWFD 392 NP + P S P N A+ V Sbjct: 1198 NPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNT 1257 Query: 393 NAATPEQRDSAH---LLSGGGLPPEIDR 417 NA + R A L G + I + Sbjct: 1258 NAVLSDARAKAQFVALNVGKAVSQHISQ 1285
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.041 Identities = 9/20 (45%), Positives = 12/20 (60%) Query: 37 LIGANGVGKTTLLRILAGQS 56 L G G+GK+TL+ L G Sbjct: 601 LEGTGGIGKSTLINTLVGLD 620
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 77.7 bits (191), Expect = 2e-17 Identities = 54/265 (20%), Positives = 97/265 (36%), Gaps = 71/265 (26%) Query: 5 FIYPVSGVMRLWHYIFADLFGCSQSQAWVASLFALVVTVRSIIAPFSWMQFKSGRFAIMM 64 +++ +S + G W S+ + VR I+ P + Q+ S M+ Sbjct: 332 WLWFISQPLFKLLKWIHSFVG-----NWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRML 386 Query: 65 RPKIKRLKEEYAERTDKESILEQERRQKEIQEEY---GYSMAAGCVPALIQVPVFLGLYQ 121 +PKI+ ++E + +++R +E+ Y + GC P LIQ+P+FL LY Sbjct: 387 QPKIQAMRERLGD--------DKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYY 438 Query: 122 VLLRMARPKEGLDATVHEPIGMLTSDNVRSFLDTRFFGVPLPAYNSMSPEQLAHLGTDQP 181 +L+ +V P + + L P Sbjct: 439 MLMG----------SVE------------------LRQAPFALW-------IHDLSAQDP 463 Query: 182 TIHAFVLPLIIAACVFTTINMIVSTLRTRYSIDHDSEFAVGMYRFLIVMVLVAPIGLLQT 241 ++LP+++ +F M T T D M F+ V+ V Sbjct: 464 Y---YILPILMGVTMFFIQKM-SPTTVT------DPMQQKIMT-FMPVIFTV-------- 504 Query: 242 GIFGPIPAAICLYWVANNLWTLIQN 266 F P+ + LY++ +NL T+IQ Sbjct: 505 -FFLWFPSGLVLYYIVSNLVTIIQQ 528
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 40.6 bits (95), Expect = 1e-05 Identities = 38/141 (26%), Positives = 59/141 (41%), Gaps = 23/141 (16%) Query: 49 FKAAQPMLKEDFGLTTLQLGYIGLAFSITYGIGKTLVGYFVDGHNSKRIISTLLICASTM 108 + P + DF ++ AF +T+ IG + G D KR+ Sbjct: 33 LNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRL----------- 81 Query: 109 VLLMGLLLSYFGSVIGI----FIVLWGLNGLFQSAGGPASYSTI----SRWAPRTKRGKY 160 LL G++++ FGSVIG F L + Q AG A + + +R+ P+ RGK Sbjct: 82 -LLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKA 140 Query: 161 LGLWNASHNVG---GALAGGL 178 GL + +G G GG+ Sbjct: 141 FGLIGSIVAMGEGVGPAIGGM 161
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 32.0 bits (73), Expect = 0.004 Identities = 22/111 (19%), Positives = 48/111 (43%), Gaps = 13/111 (11%) Query: 145 SIYMVFPLFF-LYLRVLPDIRGIILVVGATAIAITSQLAQLTIGAVMGPVVSALVVIAIH 203 SI V L +++ + ++ ++ + IT L Q+ ++ V +V+ Sbjct: 143 SILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQILRQLMVICTVGFVVISIAD 202 Query: 204 FAFEAIWKGARE----REELIDELLATRNQLAETERAAGIAAERQRIAHEI 250 +AFE ++ +E ++E+ E E E + I ++R++ EI Sbjct: 203 YAFE-YYQYIKELKMSKDEIKRE-------YKEMEGSPEIKSKRRQFHQEI 245
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 57.1 bits (138), Expect = 6e-12 Identities = 30/126 (23%), Positives = 51/126 (40%), Gaps = 12/126 (9%) Query: 2 IRVLLADDHEIVRLGLRAVLESA-EDIEVIGEVATAEAAIAAAQAGGIDVILMDLRFGPG 60 +L+ADD +R L L A D+ + + A AG D+++ D+ Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRI---TSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 VQGTKLTSGADATAAIRRRMDNPPEVLVVTNYDTDADILGAIEAGALGYMLKDAPPEELL 120 + D I++ + P VLV++ +T + A E GA Y+ K EL+ Sbjct: 61 -------NAFDLLPRIKKARPDLP-VLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELI 112 Query: 121 AAVRSA 126 + A Sbjct: 113 GIIGRA 118
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 30.5 bits (68), Expect = 0.010 Identities = 16/45 (35%), Positives = 23/45 (51%) Query: 3 EMSSKKVAGFAGVAALVVASGVGAYTYTASQHDNAPRPQTATSSA 47 E+ G+ +AL+VA G+GA TA N P QT T++ Sbjct: 357 ELQLSSGIGYGLSSALIVAGGIGAGVTTALHRRNQPAEQTTTTTT 401
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 28.2 bits (62), Expect = 0.037 Identities = 29/115 (25%), Positives = 44/115 (38%), Gaps = 8/115 (6%) Query: 111 RLSDEVWKAVSGRDGRAVVTGLPMGVYLVSETPPAKRPAEYRRTLDFLITVPAGMRTADG 170 RL++E R ++ + V + P + A T + +TVP+ A Sbjct: 358 RLTNEA------RGNTTTLSVVSTDGVSVPKAVPVRMAAYNATTGLYEVTVPSTTAEAPP 411 Query: 171 NVASWSCDVQVFTKDTDDLPPTVPVFPPVESSVTLTPSSPVPGTPKTPGKPDLPE 225 + +W+ ++ P VP PV TLTP P T PG LPE Sbjct: 412 LILTWTPASPPGNQNPSSTTPVVPKPVPVYEGATLTPVKATPET--YPGVITLPE 464
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 33.6 bits (77), Expect = 0.001 Identities = 13/63 (20%), Positives = 19/63 (30%), Gaps = 17/63 (26%) Query: 119 RRRRSRQTDVQFHRADLADSDWVVHPASGLPITTVPRTILDLAQSGHEPDHLLHLVADAG 178 R Q QFH+ DLAD + + DL S + + Sbjct: 45 RLELLAQPGFQFHKIDLADREGMT----------------DLFAS-GHFERVFISPHRLA 87 Query: 179 RKY 181 +Y Sbjct: 88 VRY 90
>PF02370#M protein repeat Length = 168 Score = 28.1 bits (62), Expect = 0.033 Identities = 16/74 (21%), Positives = 34/74 (45%), Gaps = 5/74 (6%) Query: 268 DREERETMQRYWSGEELTPKREQAREDRANLDAREAEIEGQVSR-EADPQ----KKQELE 322 +R+E++ E + + +E + + ++E + + + Q +Q L Sbjct: 77 ERKEKQERPERREKFERQHQDKHYQEQQKKHQQEQQQLEAEKQKLAKEKQISDASRQGLN 136 Query: 323 RDLENTRATKEVVE 336 RDLE +RA K+ +E Sbjct: 137 RDLEASRAAKKELE 150
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 510 bits (1316), Expect = 0.0 Identities = 183/399 (45%), Positives = 251/399 (62%), Gaps = 8/399 (2%) Query: 4 VLVLNSGSSSIKFQLVDPTAHATDDPFASGLVEQIGEPQGRVTLKHAGEKFVVEAPIPDH 63 +LV+N GSSS+K+QL++ + A GL E+IG +T GEK ++ + DH Sbjct: 3 ILVINCGSSSLKYQLIESK---DGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDH 59 Query: 64 SAGLALAFDLMGEHKCG--PTDVEIIAVGHRVVHGGILFSQPQVITDEIMDMVRDLIPLA 121 + L D + G EI AVGHRVVHGG F+ +ITD+++ + D I LA Sbjct: 60 KDAIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELA 119 Query: 122 PLHNPANIDGIEVARKILPDVAHVAVFDTGFFHDMPPAAAIYAIDAKTAADHGVRRYGFH 181 PLHNPANI+GI+ +I+PDV VAVFDT F MP A +Y I + + +R+YGFH Sbjct: 120 PLHNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFH 179 Query: 182 GTSHEYVSHKVAELLDLPEGAINQITLHLGNGASCAAIRGGKAIDTSMGMTPLSGLVMGT 241 GTSH+YVS + AE+L+ P ++ IT HLGNG+S AA++ GK+IDTSMG TPL GL MGT Sbjct: 180 GTSHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGT 239 Query: 242 RSGDIDPGIVFHLHRQAGMSIDEIDELLNKKSGVKGISGV-NDFRELR-TMIDAGDQDAW 299 RSG IDP I+ +L + +S +E+ +LNKKSGV GISG+ +DFR+L GD+ A Sbjct: 240 RSGSIDPSIISYLMEKENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQ 299 Query: 300 LAYNIYIHQLRRYIGSYMIALGRVNAITFTAGVGENDVAVRADALSHLEGFGIKIDPERN 359 LA N++ +++++ IGSY A+G V+ I FTAG+GEN +R L LE G K+D E+N Sbjct: 300 LALNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKN 359 Query: 360 ALPNTGPREISTDDSAIKVFVVPTNEELAIARYAKALSG 398 + IST DS + V VVPTNEE IA+ + + Sbjct: 360 KVRGE-EAIISTADSKVNVMVVPTNEEYMIAKDTEKIVE 397
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 37.0 bits (85), Expect = 3e-04 Identities = 28/82 (34%), Positives = 47/82 (57%), Gaps = 9/82 (10%) Query: 199 VLPALDYLHSRGVVYNDLKPDNIII--SEDQVKLIDLG--AVSGIGAFGYIYGTKGYQAP 254 +L ++L GVV+ND+KP N++ + + +IDLG + SG G+ T+ ++AP Sbjct: 254 LLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKGF---TESFKAP 310 Query: 255 E--VASDGPSIASDIYTIGRTL 274 E V + G S SD++ + TL Sbjct: 311 ELGVGNLGASEKSDVFLVVSTL 332
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 44.6 bits (105), Expect = 9e-08 Identities = 16/60 (26%), Positives = 27/60 (45%) Query: 224 DGYLGYSAVEVAPEYRRQGLATELGAAMLAWGKAHGAHTAYLQVIESNAAGIGLYHKLGF 283 +GY + VA +YR++G+ T L + W K + L+ + N + Y K F Sbjct: 87 NGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.5 bits (63), Expect = 0.019 Identities = 26/150 (17%), Positives = 52/150 (34%), Gaps = 15/150 (10%) Query: 31 VTSDNSSSAPKTSTAETSEQTPAEKSAPQA-PAASDTP--------APSDAPGESAAPAE 81 V ++ + PK ++ + +Q +E PQA PA + P + ++ ++ PA+ Sbjct: 1114 VETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAK 1173 Query: 82 KAPAD--RPADKPAAERPVPVRVLNNSTVQGLAAQVADTLRSHGI----DVVEVGNLPDA 135 + ++ +P + V N Q S V ++P Sbjct: 1174 ETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHN 1233 Query: 136 VVPETTVFYPAGHQAQAQKIADQLHAAIAQ 165 V P TT A + +A ++ Sbjct: 1234 VEPATTSSNDRSTVALCDLTSTNTNAVLSD 1263
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 42.3 bits (99), Expect = 6e-07 Identities = 21/42 (50%), Positives = 25/42 (59%) Query: 131 NSDQPDDSKKPEGQGNPGGSNNPKLPNNPKLPNNPKLPNNPD 172 N DQP++ P+ NP NNP PNNP PNNP P+N D Sbjct: 285 NDDQPNNPDNPDNPNNPDNPNNPDEPNNPDNPNNPDNPDNGD 326 Score = 36.1 bits (83), Expect = 7e-05 Identities = 20/38 (52%), Positives = 21/38 (55%), Gaps = 1/38 (2%) Query: 147 PGGSNNPKLPNNPKLPNNPKLPNNPDVTPAPPSNDGAG 184 P +NP PNNP PNNP PNNPD P P N G Sbjct: 289 PNNPDNPDNPNNPDNPNNPDEPNNPD-NPNNPDNPDNG 325 Score = 32.7 bits (74), Expect = 0.001 Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 8/67 (11%) Query: 115 ENFRDALAACIAGKYYNSDQPDDSKKPEGQGNPGGSNNPKLPNNPKLPNNPKLPNNPDVT 174 EN R+ L I ++ +D +P NP NNP PNNP PNN P+NP+ Sbjct: 268 ENVRNFLKQNIEDIHFANDD-----QPNNPDNPDNPNNPDNPNNPDEPNN---PDNPNNP 319 Query: 175 PAPPSND 181 P + D Sbjct: 320 DNPDNGD 326
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.008 Identities = 18/95 (18%), Positives = 29/95 (30%), Gaps = 10/95 (10%) Query: 20 PTFQAERIRKCLRDGSEEVLSRYSVRMREYWIL-----GFVAGVEPPTQVAIAAALGVDP 74 F+ E+ + + G + L R G+ T + ALG DP Sbjct: 752 IYFRPEQELRLVETGVQGRLWALLTREGAPAAEGAAQKGYSVNTTFVTIADLVQALGADP 811 Query: 75 S-----DMVRLIDSVESRGWVRRELDPRDRRRHLV 104 ++ D + GW RRR + Sbjct: 812 GKSSPMLEGQVRDWLNENGWEYLRETSGQRRRGYM 846
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.1 bits (73), Expect = 0.010 Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 18/88 (20%) Query: 200 AKIPRGVLLYGPPGTGKTLLARAV---AGEAGVPFYS-----ISGSDFVEMFVGV----- 246 + +++ G GTGK L+ARA+ PF + I G Sbjct: 157 MQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAF 216 Query: 247 -GASRVRD-LFKQARENSPCIIFIDEID 272 GA F+QA + +F+DEI Sbjct: 217 TGAQTRSTGRFEQAEGGT---LFLDEIG 241
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.7 bits (72), Expect = 0.012 Identities = 33/173 (19%), Positives = 66/173 (38%), Gaps = 31/173 (17%) Query: 531 IIGQDDAVKSVSRAIRRTRAGLKDPRRPSGSFIFAGPSGVGKTELSKSLANFLFGDDDAL 590 ++G+ A++ + R + R + + G SG GK ++++L ++ + Sbjct: 139 LVGRSAAMQEIYRVLARLMQT-------DLTLMITGESGTGKELVARALHDYGKRRNGPF 191 Query: 591 IQIDMGEFHDRFTASRLFGAPPGYVGYDEGGQLTEKVRRKP--FS-----VVLFDEIEKA 643 + I+M S LFG E G T R F + DEI Sbjct: 192 VAINMAAIPRDLIESELFGH--------EKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDM 243 Query: 644 HKEIYNTLLQVLEEG---RLTDGQGRVVDFKNTVLIFTSNLGTQDISKAVGMG 693 + LL+VL++G + D + ++ +N +D+ +++ G Sbjct: 244 PMDAQTRLLRVLQQGEYTTVGGRTPIRSDVR---IVAATN---KDLKQSINQG 290
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 38.4 bits (89), Expect = 3e-06 Identities = 17/70 (24%), Positives = 27/70 (38%), Gaps = 15/70 (21%) Query: 90 AYLHKLAVRRTHAGRGVSSALIEACRHAARTQGCAKLRLD--------CHPNLRGLYERL 141 A + +AV + + +GV +AL+ A+ L L+ CH Y + Sbjct: 90 ALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACH-----FYAKH 144 Query: 142 GFT--HVDTF 149 F VDT Sbjct: 145 HFIIGAVDTM 154
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 26.5 bits (58), Expect = 0.030 Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 6/31 (19%) Query: 43 RRRAEHLAGRWAAKEAFVKAWSQSLYGKPPV 73 +R+AEHLAGR AA A + G V Sbjct: 45 KRKAEHLAGRIAAVHALRE------VGVRTV 69
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.3 bits (151), Expect = 3e-14 Identities = 35/207 (16%), Positives = 60/207 (28%), Gaps = 21/207 (10%) Query: 16 RPAQQRSREKFDRILAAARAVLVDVGFESFTFDEVAKRAEVPIGTIYQYFANKYVMICEL 75 R +Q ++E IL A + G S + E+AK A V G IY +F +K + E+ Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 76 DRHDTAASIAEIQRFSQQVPALQWPDFLNEFIDHLSVM--WRADPSRRSVWH----AIQS 129 + + + P I L + + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 130 TPATRATAAATEQPMLDIIGDVMRP------LAPRTTPEQRLEIASLLVHTVSSLLNYAV 183 + D I ++ L A ++ +S L+ + Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTR---RAAIIMRGYISGLMENWL 179 Query: 184 HDPTSSDEVFESRVAEIKRMIVAYLFA 210 P S D + + R VA L Sbjct: 180 FAPQSFD------LKKEARDYVAILLE 200
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 28.4 bits (63), Expect = 0.009 Identities = 11/43 (25%), Positives = 22/43 (51%), Gaps = 5/43 (11%) Query: 70 SAFERTDATGTKLGDWLRANNIERLDVVGLGTELGIRSSVLDA 112 SAF+RT+ L + +R ++L + G+ +G + +A Sbjct: 127 SAFKRTN-----LLEMMRKEGRDQLIITGIYAHIGCLVTACEA 164
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 94.3 bits (234), Expect = 4e-25 Identities = 58/188 (30%), Positives = 96/188 (51%), Gaps = 9/188 (4%) Query: 12 AVVTGASQGIGRAMARDLARMGHNVLLVARREDVLRELADQLMTDHSVVAEVYPCDLADA 71 A +TGA+QGIG A+AR LA G ++ V + L E + + AE +P D+ D+ Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKL-EKVVSSLKAEARHAEAFPADVRDS 69 Query: 72 DDLRGLVAEL--QGREVNIIVNSAGIASFGP---FMDQDWQYESKQFDLNARAVFELTHA 126 + + A + + ++I+VN AG+ G D++W+ F +N+ VF + + Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWE---ATFSVNSTGVFNASRS 126 Query: 127 VLPGMVARKSGAICNVGSAAGNVPIPNNATYVLTKAGVNAFTEALHYELRKSGVACTLLA 186 V M+ R+SG+I VGS VP + A Y +KA FT+ L EL + + C +++ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 187 PGPVREAV 194 PG + Sbjct: 187 PGSTETDM 194
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.0 bits (65), Expect = 0.029 Identities = 10/27 (37%), Positives = 14/27 (51%) Query: 156 ILVTGATGGVGSIAVHLLAQRGYSIVA 182 LVTGA G +G L + G+ +V Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVG 29
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.6 bits (69), Expect = 0.013 Identities = 31/140 (22%), Positives = 54/140 (38%), Gaps = 7/140 (5%) Query: 255 LGVFMLASGLSALVGGRISGVWSDYSSRAVMSYGALASSIVVLVIVACSWWAPSALNVWL 314 G+ + L + G SD R + +LA + V I+A +A +W+ Sbjct: 45 YGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMA------TAPFLWV 98 Query: 315 FPLSFFVVNVVHTGIRVARKTYIVDMAEGDQRTRYVGAANTLMGVILLIVGVISGTIAHW 374 + V + VA YI D+ +GD+R R+ G + G ++ V+ G + + Sbjct: 99 LYIGRIVAGITGATGAVA-GAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGF 157 Query: 375 GPQPALLFLAAIGLAGAATS 394 P AA+ T Sbjct: 158 SPHAPFFAAAALNGLNFLTG 177
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 28.6 bits (64), Expect = 0.021 Identities = 13/93 (13%), Positives = 31/93 (33%), Gaps = 1/93 (1%) Query: 100 YLIEAHSAQKVAQLPSAQRTAIVAALEATIEKQEEALSRERLDLYTDFDAEFHQHIMKAA 159 YL ++ ++ LP+ +T + + E + L + + A Sbjct: 146 YLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLEKKLASLSSEDYTSAG 205 Query: 160 GNEILAHLYNSLRDKQ-ARITSRIVTRNADNAQ 191 G + + + N K I + + + A+ Sbjct: 206 GVDNVVEIINMADRKTEKFIIESLEEEDPELAE 238
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 38.0 bits (88), Expect = 3e-04 Identities = 48/270 (17%), Positives = 97/270 (35%), Gaps = 33/270 (12%) Query: 303 NAAAAAGRLASQSANMADQAVAASHEARAALRETAAALARAAAASARAQSAAAHAASAAN 362 +A +A+ L++ A+ +A A L + + + AQ AA +++A Sbjct: 250 SAISASFILSNADADTRTKAAAGVELTTKVL----GNVGKGISQYIIAQRAAQGLSTSAA 305 Query: 363 AAAYDANAAHGARIAAEQARNAAQAAEQSQQAFRYAEEAAGFAQSAGQAAGSAARNADAA 422 AA A+A A I+ + A +++ + Y++ + + A Sbjct: 306 AAGLIASAVTLA-ISPLSFLSIADKFKRANKIEEYSQRFKKLGYDGDSLLAAFHKETGAI 364 Query: 423 AAAATEAANAAGESQGAADEARAGAARARAAAGRARAAASEVDRLVANIRSLVEQTRQAA 482 A+ T A + +AA + V LV + ++ +A+ Sbjct: 365 DASLT-----------TISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEAS 413 Query: 483 KEAA-EH-ANNSAQSADDAAREAGNAHYAAQVAGRHAQFSSQSAERARNNIQLAKDIHEQ 540 K+A EH A+ A + ++ G ++ RHA F +N ++ +++ Sbjct: 414 KQAMFEHVASKMADVIAEWEKKHGKNYFENGYDARHAAF-------LEDNFKILSQYNKE 466 Query: 541 ATNSAQERLQAERAFLKEQARLAREIQDVA 570 ER+ L Q I ++A Sbjct: 467 --------YSVERSVLITQQHWDTLIGELA 488
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 38.8 bits (90), Expect = 4e-06 Identities = 14/58 (24%), Positives = 24/58 (41%) Query: 109 YFELAELHVSPRAQGQGIGRSLLHALIKHCGHELILLSTPEVPDEKNAAFHLYRSCGF 166 Y + ++ V+ + +G+G +LLH I+ E D +A H Y F Sbjct: 89 YALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 86.1 bits (213), Expect = 5e-23 Identities = 57/200 (28%), Positives = 91/200 (45%), Gaps = 25/200 (12%) Query: 38 QLSKESIISASLDILDSYGLADMTMRRLATHLGVAPGALYWHFKNKQALIDAIARHIMAP 97 +L++ES+I A+L++L+ G+ +T R+LA LG+ LYWH KNK+AL+DA+A I+A Sbjct: 3 RLNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILAR 62 Query: 98 LIDASPSAYHHD----IPSLAFDVRSLMLRHRDGAELLSAALTDAS----LRNDIISVVS 149 D S A + + A R +LR+RDGA++ D + + + Sbjct: 63 HHDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHLGTRPDEKQYDTVETQLRFMTE 122 Query: 150 AILGGCDKAYVGASTLLNFILGSCLIEQSEVQRLEIESGTTTAVR--------------- 194 D Y S + +F LG+ L EQ E + Sbjct: 123 NGFSLRDGLYAI-SAVSHFTLGAVL-EQQEHTAALTDRPAAPDENLPPLLREALQIMDSD 180 Query: 195 NHDQLFMSSLEIIIAGLKSQ 214 + +Q F+ LE +I G + Q Sbjct: 181 DGEQAFLHGLESLIRGFEVQ 200
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 30.1 bits (67), Expect = 0.007 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 6/76 (7%) Query: 48 TSKSASAKPSEP-SDAPASESAAPAPAPENGQPAPGHPAPGPIDNPEISFIPQAPVADGA 106 T SA A ++P + +E+ A PAP +P P P NP+ + P DG Sbjct: 316 TPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDAN-----PDTDGQ 370 Query: 107 PASAEDQQAIEGLVRG 122 P + D A+ G Sbjct: 371 PGTRPDSPAVPDRPNG 386
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 88.5 bits (219), Expect = 4e-22 Identities = 58/263 (22%), Positives = 104/263 (39%), Gaps = 27/263 (10%) Query: 90 PERVVVLDTGELDSVLSLGITPVGMTTTKGAN------PVPSYLADKVKDVERVGTINEL 143 P R+V L+ ++ +L+LGI P G+ T P+P V VG E Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLP-------DSVIDVGLRTEP 87 Query: 144 NIEAIAALKPDLIIGSQLRADKLYPQLSDIAPT-VFSIRPGSP----WKENFLLVGEALG 198 N+E + +KP ++ S L+ IAP F+ G +++ + + L Sbjct: 88 NLELLTEMKPSFMVWSA-GYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLN 146 Query: 199 MEKEAEEKLNEYADRVAELKNNVPQNTE--VSLVRFM-PNKLRLYGNKSLIGVVLADAGL 255 ++ AE L +Y D + +K + + L + P + ++G SL +L + G+ Sbjct: 147 LQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGI 206 Query: 256 ARPEKQNVDDLAVE-ISPENIDQAAGSVIFYTSYGKPDATGETAVVEGPAWKNLEAVAAG 314 + + +S + + + + A++ P W+ + V AG Sbjct: 207 PNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDM--DALMATPLWQAMPFVRAG 264 Query: 315 KAHRVNDDVWFLGLGPTGAMEIV 337 + RV VWF G AM V Sbjct: 265 RFQRV-PAVWFYG-ATLSAMHFV 285
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 38.3 bits (89), Expect = 1e-04 Identities = 26/215 (12%), Positives = 66/215 (30%), Gaps = 20/215 (9%) Query: 190 KKGGELGIAETAVAEAEQAVLAATQQKETLDRRVESVAGFQRDRDQAQQ-DLPNARDTLT 248 +KG L AEA+ ++ + L++ + + ++ + LP+ Sbjct: 119 RKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQN 178 Query: 249 TREQELKTA-ELAAQQLENASAQLKIAQDQERILQSDIDAREELRKEQSRLSEALQIRI- 306 E+E+ L +Q Q + +++ LS + R+ Sbjct: 179 VSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLD 238 Query: 307 -------------QEELDLKEKTDSLSEAREKLRSQHEKARADAEKMRQRLEKLKESLRL 353 L+ + K +SQ E+ ++ ++ + + + + Sbjct: 239 DFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN 298 Query: 354 DTLRTSYQELLTVSKQLEELRTVPEVTGAQLSAAE 388 + L +L + + L + A+ Sbjct: 299 EIL----DKLRQTTDNIGLLTLELAKNEERQQASV 329
>SECETRNLCASE#Bacterial translocase SecE signature. Length = 127 Score = 38.3 bits (89), Expect = 1e-05 Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 14/100 (14%) Query: 56 SAQQEADSAEKDGFEALG-LPDAILKAVAKVG----FETPSPIQAQTIPVLMQGHDVMGL 110 SA EA + + G EA+ + L VA VG + P++A + +L+ G+ Sbjct: 2 SANTEAQGSGR-GLEAMKWVVVVALLLVAIVGNYLYRDIMLPLRALAVVILIAA--AGGV 58 Query: 111 AQTGTGKTAAFALPILSRIDVKKRHPQALILAPTRELALQ 150 A T A A +R +V+K ++ PTR+ L Sbjct: 59 ALLTTKGKATVAFAREARTEVRK------VIWPTRQETLH 92
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 33.9 bits (77), Expect = 0.005 Identities = 15/61 (24%), Positives = 20/61 (32%), Gaps = 1/61 (1%) Query: 48 EAKNTSPQPAAPAKKQPAPAKKPAPTTASAPASTEAKAAPKPENKKPAKKQQPSPLERTG 107 +A+ + A A P KP +A KP K K+ L TG Sbjct: 451 QAEELAKLRAGKASDSQTPDAKPGNKAVP-GKGQAPQAGTKPNQNKAPMKETKRQLPSTG 509 Query: 108 E 108 E Sbjct: 510 E 510
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 32.5 bits (74), Expect = 0.003 Identities = 31/146 (21%), Positives = 57/146 (39%), Gaps = 19/146 (13%) Query: 189 IATVLYELPDAQRANVAKELDDDRLADVLQEMS-------EDRQAELIETLDIERAADVL 241 A +L + + V K L + + + E++ E + L+E ++ A + + Sbjct: 21 AAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFKELMMAQEFI 80 Query: 242 EEMDPDDAADLLGE-LDDDKAD-VLLELMDPEESAPVRRLMSFSPDTVGALMTPEPLILS 299 ++ D A +LL + L KA ++ L +S P + P + + E Sbjct: 81 QKGGIDYARELLEKSLGTQKAVDIINNLGSALQSRPFEFVRRADPANILNFIQQE----H 136 Query: 300 PQTTVAEALALARNPDLPTSLASIVF 325 PQT AL L+ L AS + Sbjct: 137 PQTI---ALILSY---LDPQKASFIL 156
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 55.0 bits (132), Expect = 3e-12 Identities = 26/80 (32%), Positives = 44/80 (55%), Gaps = 5/80 (6%) Query: 1 MFSSIGWPEIFTVLILGLIIIGPERLPKVIEDVRAAIYAAKKAINNAKEELNGNLGAEFD 60 MF IG+ E+ V I+GL+++GP+RLP ++ V I A + + EL L + Sbjct: 1 MFD-IGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQ-- 57 Query: 61 EFREPINK--IASIQRMGPK 78 EF++ + K AS+ + P+ Sbjct: 58 EFQDSLKKVEKASLTNLTPE 77
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 179 bits (455), Expect = 1e-50 Identities = 98/443 (22%), Positives = 181/443 (40%), Gaps = 60/443 (13%) Query: 7 RNVAIVAHVDHGKTTLVDAMLRQSGAFDEHAELVDR---VMDSGDLEKEKGITILAKNTA 63 N+ ++AHVD GKTTL +++L SGA E VD+ D+ LE+++GITI T+ Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGS-VDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 64 VRRRGAGKDGNDVVINVIDTPGHADFGGEVERALSMVDGVVLLVDASEGPLPQTRFVLGK 123 + + +N+IDTPGH DF EV R+LS++DG +LL+ A +G QTR + Sbjct: 63 FQW-------ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHA 115 Query: 124 ALAAKMPVVILVNKTDRPDARIDEVVEE-----SQDLLLELASAL------DDPEAAEAA 172 +P + +NK D+ + V ++ S +++++ L + +E Sbjct: 116 LRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQW 175 Query: 173 EQLL----DLPVLYASGREGKAS-------------TVNPG-NGNVPDAEDLQALFDVIY 214 + ++ DL Y SG+ +A ++ P +G+ + + L +VI Sbjct: 176 DTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT 235 Query: 215 EVMPEPTVNVDGPLQAHVTNLDSSSFLGRIGLIRVHSGSLKKGQQVAWIHYDEEGNQHTK 274 T L V ++ S R+ IR++SG L V + Sbjct: 236 NKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVR--------ISEKE 287 Query: 275 TAKIAELLRTVGVTRVPADEVVAGDIAAISGIDSIMIGDTLADLEHPVALPRITVDEPAI 334 KI E+ ++ D+ +G+I + + + + L D + RI P + Sbjct: 288 KIKITEMYTSINGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPLL 346 Query: 335 SMTIGVNTSPLAGRGGGDKLTARVVKARLEQELIGNVSLRVLPTERPDAWEVQGRGEMAL 394 T+ + + L + + LR + G++ + Sbjct: 347 QTTVEPSKPQQREM----------LLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQM 396 Query: 395 SVLVETMRRE-GFELTVGKPQVV 416 V ++ + E+ + +P V+ Sbjct: 397 EVTCALLQEKYHVEIEIKEPTVI 419 Score = 37.5 bits (87), Expect = 1e-04 Identities = 16/81 (19%), Positives = 29/81 (35%), Gaps = 11/81 (13%) Query: 424 LFEPYEHMVIDIPSEYQGNVTQLMAARKGQMLSMDNISDEWVRMEYKVPAR--------- 474 L EPY I P EY ++ + + V + ++PAR Sbjct: 535 LLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCIQEYRSDL 593 Query: 475 -GLISFRTMFMTETRGTGIAN 494 + R++ +TE +G + Sbjct: 594 TFFTNGRSVCLTELKGYHVTT 614
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 38.4 bits (89), Expect = 1e-05 Identities = 33/163 (20%), Positives = 60/163 (36%), Gaps = 42/163 (25%) Query: 48 CTGTLVSPTTVLTARHCLNGGLG---------HVRLGADH----FTAVRAVAHP-QADLA 93 +G +V T+LT +H ++ G ++ FTA + + + DLA Sbjct: 104 ASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLA 163 Query: 94 VLHLD------------RPAPIAPSAISGRHTQPGNRFGVAGYGSTFPGIPMAAAATMQR 141 ++ +PA ++ +A + Q V GY P ATM Sbjct: 164 IVKFSPNEQNKHIGEVVKPATMSNNAET----QVNQNITVTGYPGDKP------VATMWE 213 Query: 142 RVTDVPSPDRQAVMIENHISQGVLRPGDSGGPLL-EGNHVVGV 183 + +A+ + + G+SG P+ E N V+G+ Sbjct: 214 SKGKITYLKGEAMQYDLSTT-----GGNSGSPVFNEKNEVIGI 251
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 29.5 bits (66), Expect = 0.013 Identities = 18/103 (17%), Positives = 36/103 (34%), Gaps = 5/103 (4%) Query: 98 TPDDGAVAFLVWGDPSLYDSTLRIIEHMRNLEDLHADVKVIP-----GITAVQVLTAEHG 152 D+ A LV G+P+ + +I+ + + + KVI V+VLT Sbjct: 232 VADERTNAVLVSGEPNSRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISS 291 Query: 153 ILINRIGEAIHITTGRNLPETSAKDRRNCVVMLDGKTAWQDVA 195 + + A + A + N +++ D+ Sbjct: 292 TMQSEKQAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLE 334
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 33.0 bits (75), Expect = 0.003 Identities = 12/88 (13%), Positives = 19/88 (21%), Gaps = 11/88 (12%) Query: 435 PAPPQPVHPMDVTPPTPVPTPDLDPVPGGNTTA---------PTPVLPPADPQPVAP--D 483 P+P PP P P P P + P + +P +P + Sbjct: 68 VVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFEN 127 Query: 484 LDKGTDTRPPLGLKELGGDGASPEDLYP 511 T + Sbjct: 128 TAPARLTSSTATAATSKPVTSVASGPRA 155 Score = 30.3 bits (68), Expect = 0.023 Identities = 20/70 (28%), Positives = 27/70 (38%), Gaps = 2/70 (2%) Query: 437 PPQPVHPMDVTPPTPVPTPDLDPVPGGNTTAPTPVLPPADPQPVAPDLDKGTDTRPPLGL 496 PPQ V P P P P+ +P+P AP + P P K +P + Sbjct: 57 PPQAVQP--PPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDV 114 Query: 497 KELGGDGASP 506 K + ASP Sbjct: 115 KPVESRPASP 124
>PF04183#IucA / IucC family Length = 580 Score = 183 bits (466), Expect = 5e-51 Identities = 104/488 (21%), Positives = 175/488 (35%), Gaps = 35/488 (7%) Query: 18 GRLLAALIDEHLITPETH---HKLTNTTTPPADLLRQLAQDNQLTITPTNLERACAEIAD 74 ++L+ L E + E+ N + + L I L A + Sbjct: 15 AKMLSELEYEQVFHAESQGDDRYCINLPGAQWRFIAERGIWGWLWIDAQTLRCADEPVLA 74 Query: 75 SVVGLHRARTAITQRWEQALNAQTATNTSQTPYSDLIQALRQRCRLEDRGSSAMLARCEQ 134 + + + A A+ + T DL Q L+ R L + A Q Sbjct: 75 QTLLMQLKQV---LSMSDATVAEHMQDLYATLLGDL-QLLKARRGLSASDLINLNADRLQ 130 Query: 135 LVCDGHPAHPAAKTSLGIG-DSFLHVLPEQTETIQLRFVAVDTDHAVV--VGGHPVETI- 190 + GHP K G G ++ PE T +L ++AV +H + + + Sbjct: 131 CLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRCDNEMDIHQLL 190 Query: 191 -SEAMPLLGARLNAELERCELHHHSV-IPVHPFQWDNVISSEFAEEIASGTIVLL-ETTA 247 + P AR + + L H+ + +PVHP+QW I+++F + A G +V L E Sbjct: 191 TAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEGRMVSLGEFGD 250 Query: 248 TAEPLMSVRTLRVSDATGSMHIKVALEIQLTGAVRGVS-AGAVAAPAIASIIDDACTLDA 306 S+RTL + G + IK+ L I T RG+ A P + + DA Sbjct: 251 QWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDA 310 Query: 307 GFIPRTDT--DQPAFSVAYDRSAIRWNADSGIRAHCFGAVLRDDP-TGNADDEIAMPVAT 363 + +PA G + R++P DE + +AT Sbjct: 311 TLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMAT 370 Query: 364 LLARNPLTGATIAADLIDELSHRHNRHRDEIATDWFTALGKFLFVPAVALIARWGIALEP 423 L+ + +A ID A W T L + + VP L+ R+G+AL Sbjct: 371 LMECDE-NNQPLAGAYIDRS--------GLDAETWLTQLFRVVVVPLYHLLCRYGVALIA 421 Query: 424 HPQNTVIILRDGMPHRIVVRDLGGCRLWANGPLAAH--------PIVDKLRATALIENDL 475 H QN + +++G+P R++++D G + +L A LI + Sbjct: 422 HGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSRLSADYLIHDLQ 481 Query: 476 IRLIDKVF 483 V Sbjct: 482 TGHFVTVL 489 Score = 177 bits (450), Expect = 7e-49 Identities = 99/519 (19%), Positives = 183/519 (35%), Gaps = 46/519 (8%) Query: 569 ISPLENLELLTPES-------LRAACAPYSEWAHETLATRLHDAAVRERIDDS------- 614 +S LE ++ ES + A + A + L A R D Sbjct: 18 LSELEYEQVFHAESQGDDRYCINLPGAQWRFIAERGIWGWLWIDAQTLRCADEPVLAQTL 77 Query: 615 FPTLRDDIANAEENLALVRAQVTSRVNTPESYWDLLKGLP---PHAAMIAADSYAISGHN 671 L+ ++ ++ +A + + + +GL +SGH Sbjct: 78 LMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINLNADRLQCLLSGHP 137 Query: 672 VHPLAKLRRGFSIEESAAYGPEAGMSTDLRLVGVDKRMIDTSTTADC---VRLIAHHFPQ 728 K RRG+ E Y PE + L + V + + + L A PQ Sbjct: 138 KFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRCDNEMDIHQLLTAAMDPQ 197 Query: 729 HIAYARTHLHEHGLDADSYAIIPVHPWQLEHVIREAFAEDIADHTMVPIPNIAIAAHPTI 788 A E+GLD ++ +PVHPWQ + I F D A+ MV + Sbjct: 198 EFARFSQVWQENGLD-HNWLPLPVHPWQWQQKIATDFIADFAEGRMVSLGEFGDQWLAQQ 256 Query: 789 SLRTLVPHAPTPSGTRPFIKCAVDVTLTSTRRSISQDSALGTPRVAGLVATALEQLRRET 848 SLRTL +A IK + + TS R I P + + T Sbjct: 257 SLRTLT-NASRRG--GLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATD--AT 311 Query: 849 NVQPRAVVVPELSGLALSRDERSEGIDDSFRKTRQRGLSVLLRDDATAYLAPGEIAMSAC 908 VQ AV++ E + +S + + +R Q L V+ R++ +L P E + Sbjct: 312 LVQSGAVILGEPAAGYVSHEGYAALARAPYR--YQEMLGVIWRENPCRWLKPDESPVLMA 369 Query: 909 AL----RGHEGVVPSPLRDIN---EEFFDDYVYDLMSTVLGLMMVKGIALEQHLQNTLVR 961 L ++ + + + E + ++ + L+ G+AL H QN + Sbjct: 370 TLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITL- 428 Query: 962 IDLSGKTPVYRGIMLRDFSG-LRAWAPRLQQWASDQVFEPGAIT-LTDDH-EEFVNKGFY 1018 + P ++L+DF G +R + S + L+ D+ + G + Sbjct: 429 -AMKEGVPQ--RVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSRLSADYLIHDLQTGHF 485 Query: 1019 ASVFGNLDGIVDEYSQARGVDAQSLWERVHVQINRFVQE 1057 +V + ++ GV + ++ + ++ ++++ Sbjct: 486 VTVLRFISPLMVRL----GVPERRFYQLLAAVLSDYMKK 520
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.1 bits (78), Expect = 1e-04 Identities = 12/65 (18%), Positives = 23/65 (35%), Gaps = 1/65 (1%) Query: 74 VHTVGVDPRWQRRGFGRLVMDNFVHVADTAG-GPIFLEVRTTNAPAIALYESLGFEHQGV 132 + + V ++++G G ++ + A + LE + N A Y F V Sbjct: 92 IEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAV 151 Query: 133 RKNYY 137 Y Sbjct: 152 DTMLY 156
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.7 bits (61), Expect = 0.022 Identities = 7/20 (35%), Positives = 11/20 (55%) Query: 35 VIILDGPLGAGKTTFTQGLA 54 ++L+G G GK+T L Sbjct: 598 SVVLEGTGGIGKSTLINTLV 617
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 284 bits (728), Expect = 7e-96 Identities = 97/369 (26%), Positives = 154/369 (41%), Gaps = 24/369 (6%) Query: 5 ETRISCDAIAANTRRLKDMVAPAQLMCVVKADGYNHGAPEVATVMARNGADQFGVATLAE 64 + + A+ N ++ A++ VVKA+ Y HG + + A D F + L E Sbjct: 6 QASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWS--AIGATDGFALLNLEE 63 Query: 65 AHQLRDAGITLPIL-CWIWSPEQDFSAAIDRDIDLAAVSMDHVRALIAEAMRRPAGTRVR 123 A LR+ G PIL + QD + S ++AL ++ P + Sbjct: 64 AITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAP----LD 119 Query: 124 VTVKIDTELHRSGIDEANWTEAFELLHACPQVNVTGVFSHLACADDLESDYTDHQAEVFR 183 + +K+++ ++R G ++ L A V + SH A A+ D Sbjct: 120 IYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAE--HPDGISGAMARIE 177 Query: 184 RAISAGRNVGLDLPVNHLAASPATLTRPDLHFDMVRPGLALYGHEPIAG----LDHGLRE 239 +A GL+ L+ S ATL P+ HFD VRPG+ LYG P + GLR Sbjct: 178 QAAE-----GLECRR-SLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRP 231 Query: 240 AMTWIGSVTVVKPIAAGQGTSYNMTWHAPADGYLCVVPVGYADGLPRNVQGHLEVTIAGT 299 MT + V+ + AG+ Y + A + + +V GYADG PR+ V + G Sbjct: 232 VMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGV 291 Query: 300 RYPQVGRVCMDQIVVFLGDNSRGVAPGDEAIIFGPRDTQAMTVTELACATGTINYEILCR 359 R VG V MD + V L + G ++G + + ++A A GT+ YE++C Sbjct: 292 RTMTVGTVSMDMLAVDLTPCPQ-AGIGTPVELWGKE----IKIDDVAAAAGTVGYELMCA 346 Query: 360 PTGRSHRTY 368 R Sbjct: 347 LALRVPVVT 355
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 41.1 bits (96), Expect = 4e-06 Identities = 17/56 (30%), Positives = 23/56 (41%), Gaps = 3/56 (5%) Query: 370 VPPPPTPDVPPPPAPAPPPVIDNVPEPPPPPKQIPGMVPAAAPAPPPAPEPPAPAP 425 + PP PP P P P + +PEPP P ++ P P P P+P Sbjct: 60 LEPPQAVQPPPEPVVEPEPEPEPIPEPPKEA---PVVIEKPKPKPKPKPKPVKKVE 112 Score = 35.7 bits (82), Expect = 2e-04 Identities = 15/59 (25%), Positives = 19/59 (32%) Query: 370 VPPPPTPDVPPPPAPAPPPVIDNVPEPPPPPKQIPGMVPAAAPAPPPAPEPPAPAPLSS 428 V P P P P PV+ P+P P PK P E +P + Sbjct: 73 VVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFEN 131 Score = 33.4 bits (76), Expect = 0.001 Identities = 10/55 (18%), Positives = 13/55 (23%) Query: 371 PPPPTPDVPPPPAPAPPPVIDNVPEPPPPPKQIPGMVPAAAPAPPPAPEPPAPAP 425 P + P P P P A+P AP P + Sbjct: 87 PKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSST 141 Score = 33.4 bits (76), Expect = 0.001 Identities = 17/55 (30%), Positives = 19/55 (34%), Gaps = 4/55 (7%) Query: 371 PPPPTPDVPPPPAPAPPPVIDNVPEPPPPPKQIPGMVPAAAPAPPPAPEPPAPAP 425 PP P V P P P P P+P +Q V P E APA Sbjct: 86 PPKEAPVVIEKPKPKPKP----KPKPVKKVEQPKRDVKPVESRPASPFENTAPAR 136 Score = 32.6 bits (74), Expect = 0.002 Identities = 11/55 (20%), Positives = 12/55 (21%) Query: 371 PPPPTPDVPPPPAPAPPPVIDNVPEPPPPPKQIPGMVPAAAPAPPPAPEPPAPAP 425 P P P P P D P P PA + P Sbjct: 97 PKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVT 151 Score = 30.3 bits (68), Expect = 0.011 Identities = 21/53 (39%), Positives = 23/53 (43%), Gaps = 4/53 (7%) Query: 377 DVPPPPAPAPPPVIDNVP----EPPPPPKQIPGMVPAAAPAPPPAPEPPAPAP 425 V PAPA P + V EPP + P V P P P PEPP AP Sbjct: 39 QVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAP 91
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 29.3 bits (66), Expect = 0.027 Identities = 13/21 (61%), Positives = 17/21 (80%) Query: 346 HDRGAIEVGKRADLVLCSGDF 366 H+ G++EVGKRADLVL + F Sbjct: 421 HEIGSLEVGKRADLVLWNPAF 441
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 46.8 bits (111), Expect = 1e-07 Identities = 62/326 (19%), Positives = 118/326 (36%), Gaps = 46/326 (14%) Query: 51 IQKEFGLSDTQLSWILAVAILNGSMWRLPAGILADKIGGRKV-MLGITLFSAVASLGVAF 109 I +F +W+ +L S+ G L+D++G +++ + GI + S+ Sbjct: 40 IANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIIN-CFGSVIGFV 98 Query: 110 SQNYTMTLVLA-FLVGFCGNSFTAGAAWASAWF-PKHKQGFALGVFGA-GNVGASVTKFI 166 ++ L++A F+ G +F A A + PK +G A G+ G+ +G V I Sbjct: 99 GHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAI 158 Query: 167 GPVIIASTAGATYFGFIP-----AGWRLIPI------------IYSVTLVIVAILMMIYT 209 G +IA +Y IP L+ + I + L+ V I+ + Sbjct: 159 GG-MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLF 217 Query: 210 PKVDRFGSSGRSLAEMLLPLKQVR----------------VWRFSLYYVVVFGAYVALSA 253 S+ L+ +K +R L ++FG + Sbjct: 218 TTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS 277 Query: 254 TLPKYYISNYDVSLAAAGLLTAIFIFPASL----LRPVGGWFSDRYGARRAMYGTFFVMG 309 +P + +S A G ++ IFP ++ +GG DR G + + Sbjct: 278 MVPYMMKDVHQLSTAEIG---SVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS 334 Query: 310 TAAGLLCLPSNIINIFVFTLLIFSLG 335 + + F+ +++F LG Sbjct: 335 VSFLTASFLLETTSWFMTIIIVFVLG 360
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.2 bits (65), Expect = 0.027 Identities = 17/75 (22%), Positives = 31/75 (41%), Gaps = 1/75 (1%) Query: 64 KLDEYTSGLDSVSGSFEAAGAQHVTTANPEIPQDIGAAAFFDIDNTLIQGSSLVVFAMGL 123 LD +GLD+VSG A A + +N + AAA ++ ++ + + Sbjct: 234 NLDNIGAGLDTVSGILSAISASFIL-SNADADTRTKAAAGVELTTKVLGNVGKGISQYII 292 Query: 124 AKKKYFKLNEILPVA 138 A++ L+ A Sbjct: 293 AQRAAQGLSTSAAAA 307
>PRPHPHLPASEC#Prokaryotic zinc-dependent phospholipase C signature. Length = 398 Score = 28.4 bits (63), Expect = 0.032 Identities = 17/97 (17%), Positives = 34/97 (35%), Gaps = 11/97 (11%) Query: 120 EFSDFECPFCARWSNQTEPTLMEEYVSKGLVRIEWNDLPVNGEHALAAAKAGRAAAAQGK 179 +F+ + + ++ + Y S + W+D + LA ++ G A G Sbjct: 212 DFNAWSKEYARGFAKTGK----SIYYSHASMSHSWDDWDYAAKVTLANSQKGTA----GY 263 Query: 180 FDEFRKALFEASRNVSGHPNNTLKDFERFARNAGVKD 216 F L + S +K+ + +G KD Sbjct: 264 IYRF---LHDVSEGNDPSVGKNVKELVAYISTSGEKD 297
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.2 bits (216), Expect = 5e-22 Identities = 30/118 (25%), Positives = 61/118 (51%), Gaps = 1/118 (0%) Query: 2 TSILLVEDEESLADPLAFLLRKEGFDVVIAGDGPSALVEFDRNAIDIVLLDLMLPGMSGT 61 +IL+ +D+ ++ L L + G+DV I + + D+V+ D+++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 DVCKRLRAV-SSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRR 118 D+ R++ +PV++++A+++ + + E GA DY+ KP+ ELI I L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>PF06580#Sensor histidine kinase Length = 349 Score = 32.9 bits (75), Expect = 0.002 Identities = 25/110 (22%), Positives = 43/110 (39%), Gaps = 23/110 (20%) Query: 264 LLVTAVSNLISNAINYSPQGMPISVATKISRDGRVLIRVIDNGIGISVENQKRVFERFFR 323 L+ T V N I + I PQG I + +G V + V + G ++++N K Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGT-KDNGTVTLEVENTG-SLALKNTKE------- 309 Query: 324 VDKARSRSTGGTGLGLAIVKH-VAANHGGD--VTLWSRPGTGSTFTIELP 370 TG GL V+ + +G + + L + G + +P Sbjct: 310 ----------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKV-NAMVLIP 348
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 29.6 bits (66), Expect = 0.006 Identities = 14/83 (16%), Positives = 24/83 (28%), Gaps = 5/83 (6%) Query: 35 LSPEPGEVHEFTEANGGAVATLFEVLPQELLPEAIRAMISQALKVKRVVTVGGLNGTSAP 94 L+P PG +A G V + + EA V G+ G Sbjct: 190 LTPVPGNWIYMIDAADGKV-----LNKWNQMDEAKPGGAQPVAGTSTVGVGRGVLGDQKY 244 Query: 95 LSYTADVKGTPVDFKGEISMNGL 117 ++ T + +G+ Sbjct: 245 INTTYSSYYGYYYLQDNTRGSGI 267
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 41.5 bits (97), Expect = 2e-06 Identities = 33/241 (13%), Positives = 68/241 (28%), Gaps = 42/241 (17%) Query: 31 TNGTPVSPADDTAAEGVVQVAS--------CTGTVVASQWVLTAQHCVE----VPNLQRP 78 + ++ + V + +G VV +LT +H V+ P+ + Sbjct: 74 NDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHVVDATHGDPHALKA 133 Query: 79 VYVGTTREQQRREENTFTSDYAVWAPHGDVALVHVTDALPQRLVRKV-------RRAPVS 131 ++ ++ GD+A+V + + + +V A Sbjct: 134 FPSAINQD-NYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQ 192 Query: 132 FGEQGRVYGWGAGTGETLQYARAAVGKTSSGVRPQGNQHGAFIVQYLDEAKAGRGDSGGP 191 + V G+ + G Q+ G+SG P Sbjct: 193 VNQNITVTGYPGDKPVATMWESKGKITYLKGE---AMQYDLSTTG---------GNSGSP 240 Query: 192 LF-VDGEVAGVTSFKAPQGGGRFSLFASLHGLGDWIAQ-------TTAAPSPSPRNPNSK 243 +F EV G+ P + +++ Q +P NP++ Sbjct: 241 VFNEKNEVIGIHWGGVPNEFNGAVFINE--NVRNFLKQNIEDIHFANDDQPNNPDNPDNP 298 Query: 244 N 244 N Sbjct: 299 N 299
>BORPETOXINA#Bordetella pertussis toxin A subunit signature. Length = 269 Score = 27.8 bits (61), Expect = 0.034 Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 5/56 (8%) Query: 74 YPSYRYIDKIAGTTVPPVPDSLAALAPEALRAAAEVAEELAPWVETFVPEMVLVNY 129 Y S R + I GT V P A +A +A E +E +A W E MVLV Y Sbjct: 212 YTSRRSVASIVGTLVRMAPVIGACMARQA-----ESSEAMAAWSERAGEAMVLVYY 262
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 39.8 bits (93), Expect = 2e-05 Identities = 26/130 (20%), Positives = 50/130 (38%), Gaps = 28/130 (21%) Query: 19 RVVVTGASGYVGARLVVELLSTGFNVRATSRSLSSLKRFPWYDQ--------------VE 64 + +VTGA+G++G + LL G V + +L +YD + Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVG----IDNLN--DYYDVSLKQARLELLAQPGFQ 55 Query: 65 AVEADLSISEDVNRLFED--VDTVFYLVHSMSGTQNFEELESKIASKVA------QAAHS 116 + DL+ E + LF + VF H ++ + E + S + + Sbjct: 56 FHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRH 115 Query: 117 NGVRQIIYLS 126 N ++ ++Y S Sbjct: 116 NKIQHLLYAS 125
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 56.4 bits (136), Expect = 7e-11 Identities = 83/384 (21%), Positives = 148/384 (38%), Gaps = 38/384 (9%) Query: 10 ITFLLVTQMLFSIGFYLVVPFLAVQLSENLGASGTIV---GLVLGIRTFSQQGLFFFGGG 66 + +L T L ++G L++P L L + L S + G++L + Q G Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRD-LVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 67 LADKFGAGPILLIGVAIRVIGFLTVGMAETVTLMTLGVVLIGFAAALFSPAVESIFAAEG 126 L+D+FG P+LL+ +A + + + A + ++ +G ++ G A + A Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATG-AVAGAYIA--- 121 Query: 127 HRLEKLGVITRARLFALDAAYSRIGTLTGPVIGAVLIPLGFATVSIAGAAIFGSIFVI-H 185 + RAR F +A G + GPV+G ++ A AA+ G F+ Sbjct: 122 ---DITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGC 178 Query: 186 LALRRTWTASAQPQRTHAPSMMAVWGEVIRNKKFVVFALLYSTYLLA--YNQQYLSLPVE 243 L + +P R A + +A + V A L + + + Q +L V Sbjct: 179 FLLPESHKGERRPLRREALNPLAS---FRWARGMTVVAALMAVFFIMQLVGQVPAALWVI 235 Query: 244 L--RRATGSDEALGWFFAVSAVFVIALQSRVT-----RWAERQAAAAALGGGFGLMALSF 296 R +G A + Q+ +T R ER+A G + Sbjct: 236 FGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALML----GMIADGTGY 291 Query: 297 AVVAVASISLELEGWIAYVPAAAMMILLHTGIMIAVPIARDLVGDLAGNNNLGSYYGFLN 356 ++A A+ GW+A+ +M+LL +G I +P + ++ G G L Sbjct: 292 ILLAFAT-----RGWMAFP----IMVLLASG-GIGMPALQAMLSRQVDEERQGQLQGSLA 341 Query: 357 SFGGLAVLLGSLTVGATLDHAETT 380 + L ++G L A + TT Sbjct: 342 ALTSLTSIVGPLLFTAIYAASITT 365
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.0 bits (72), Expect = 0.005 Identities = 11/45 (24%), Positives = 23/45 (51%) Query: 168 LIAHNTFTAEVAQILENLVRERRPLLIVGGTGSGKTTLLSALLAT 212 L+ VA+++E + +++ G G GK+TL++ L+ Sbjct: 575 LVGKYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 50.0 bits (119), Expect = 6e-09 Identities = 56/298 (18%), Positives = 105/298 (35%), Gaps = 49/298 (16%) Query: 98 AIGSVFQTLATLLVAWLVSIPLATGLSGGISQGIKNSEILGFVDHGAPSQLSALPSKISA 157 + S+F +ATL A LVS P A LS S+ + N Q + + + Sbjct: 7 KVSSLF--VATLTTATLVSSPAANALS---SKAMDN-----------HPQQTQSSKQQTP 50 Query: 158 MLNESGLPPLVSPFMEKQHSSQVEAP--AIKVADTALVERLRPSVIHVLGESEECSRRLM 215 + + G + P +++H++ + ++ DT V ++ + E + + Sbjct: 51 KIQKGGN---LKPLEQREHANVILPNNDRHQITDTTNGHY--APVTYI--QVEAPTGTFI 103 Query: 216 GSGFVVDATHVMTNAHVVAGTQRVS--LDTVVGMVDATVVYYNPQLDIAVLEAEGLNLPA 273 SG VV ++TN HVV T L ++ + + G A Sbjct: 104 ASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLA 163 Query: 274 LQWAPEPAETGADAIVMGFPES-GPFE---AAPARISDRIIIAG----PDIYANGRVERE 325 + P E E P A +++ I + G + + + Sbjct: 164 I-VKFSPNEQNKH-----IGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGK 217 Query: 326 SYTARGSIRQ-------GNSGGPMVDAEGNVIGVVFGASVDATDIGYALTAKEVLNMV 376 +G Q GNSG P+ + + VIG+ +G + + + + V N + Sbjct: 218 ITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNEFNGAVFIN-ENVRNFL 274
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 99.5 bits (248), Expect = 3e-26 Identities = 41/158 (25%), Positives = 75/158 (47%), Gaps = 4/158 (2%) Query: 1 MHRLRVLVVDDEPQMVQIISYALELEGWEVLSASSAQRGWQLLNEYRCDLVILDVMLPDA 60 M +LV DD+ + +++ AL G++V S+A W+ + DLV+ DV++PD Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 SGYALCERIRAAGDVAGTPVIMLTALGDTDNRVEGLEAGADDYVAKPFSPKELV-LRAQA 119 + + L RI+ A PV++++A ++ E GA DY+ KPF EL+ + +A Sbjct: 61 NAFDLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 120 VVRRSGGVVQPEL-REIIVGEVSVNPATHAVVIGGRRV 156 + + E + + V + A + R+ Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARL 156
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 37.7 bits (87), Expect = 2e-04 Identities = 13/39 (33%), Positives = 19/39 (48%) Query: 1011 PHPTPAPQPAPQPTPQKPSEQQPSPKAPEKKPQKEKKVL 1049 P P P+P P+P + P + P+ KP+ KKV Sbjct: 69 VEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQ 107 Score = 34.6 bits (79), Expect = 0.002 Identities = 12/47 (25%), Positives = 21/47 (44%) Query: 1008 PLFPHPTPAPQPAPQPTPQKPSEQQPSPKAPEKKPQKEKKVLARTGA 1054 P+ P AP +P P+ + +P K E+ + K V +R + Sbjct: 77 PIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPAS 123 Score = 31.9 bits (72), Expect = 0.010 Identities = 15/51 (29%), Positives = 24/51 (47%) Query: 997 PLIPLVIIPFLPLFPHPTPAPQPAPQPTPQKPSEQQPSPKAPEKKPQKEKK 1047 P P+ + P P A QP P+P + E +P P+ P++ P +K Sbjct: 41 PAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEK 91 Score = 31.5 bits (71), Expect = 0.013 Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 2/39 (5%) Query: 1011 PHPTPAPQPAPQ-PTPQKPSEQQPSPKA-PEKKPQKEKK 1047 P P P P+P + P + + +P PK P KK Q++ K Sbjct: 73 PEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPK 111 Score = 31.1 bits (70), Expect = 0.019 Identities = 10/37 (27%), Positives = 15/37 (40%) Query: 1011 PHPTPAPQPAPQPTPQKPSEQQPSPKAPEKKPQKEKK 1047 P P P P+P P+ E +KP+ + K Sbjct: 61 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPK 97
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 31.7 bits (72), Expect = 0.005 Identities = 22/100 (22%), Positives = 41/100 (41%), Gaps = 7/100 (7%) Query: 112 RIVDVTPGRVREALDEGKICLVAGFQG--VNRESKDVTTL-GRGGSDTTAVALAAALNAD 168 V+ +++ ++ G I + +G G V E ++ + D LA +NAD Sbjct: 172 GHVEAET--IKKLVERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNAD 229 Query: 169 VCEIYSDVDGVYTADPRIVPNAQKLEKLCFEEMLELAASG 208 + I +DV+G Q L ++ EE+ + G Sbjct: 230 IFMILTDVNGAALYYGT--EKEQWLREVKVEELRKYYEEG 267
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 149 bits (378), Expect = 2e-42 Identities = 96/376 (25%), Positives = 183/376 (48%), Gaps = 7/376 (1%) Query: 41 MAEGLGIDPNTASLQASLAGVIIGIGAVVYAALADAISIRKLMLIGIGLVVVGSVIGFVF 100 +A P + + + + IG VY L+D + I++L+L GI + GSVIGFV Sbjct: 40 IANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVG 99 Query: 101 SGSWPLVLAGRLIQTGGLAAAETLYVIYVTKHLAAEDQKTYLGFSTAAFQSGLLVGALTS 160 + L++ R IQ G AA L ++ V +++ E++ G + G VG Sbjct: 100 HSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIG 159 Query: 161 GAISTYIGWRVMFLVPLILIVAVPFILKTVPEEEASSSHLDVVGLFLIAIFATSVIQYMQ 220 G I+ YI W + L+P+I I+ VPF++K + +E H D+ G+ L+++ + + Sbjct: 160 GMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT 219 Query: 221 AFKLFWLAFMLVSIVIFVWYVRNAKNPVVNPEFFKNGRYVWAILLVLIVYSTQLGYIVLL 280 ++ + +L ++S +IFV ++R +P V+P KN ++ +L I++ T G++ ++ Sbjct: 220 SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMV 279 Query: 281 PFAAKEFHGLDQAQASYLMIPGYICAVLIGIFSGKIGKLMTSRRTIFTALGMIIVALVVG 340 P+ K+ H L A+ ++I + I G IG ++ RR L + + L V Sbjct: 280 PYMMKDVHQLSTAEIGSVII---FPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVS 336 Query: 341 ALAIQVHV---AVAIASIILFASGFALLYAPLVNTALANIL-PEKSGVAIGFYNLTINIG 396 L + + + II+F G +++T +++ L +++G + N T + Sbjct: 337 FLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLS 396 Query: 397 VPLGIAYTFKLMNLSI 412 GIA L+++ + Sbjct: 397 EGTGIAIVGGLLSIPL 412
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 40.8 bits (95), Expect = 2e-05 Identities = 19/90 (21%), Positives = 22/90 (24%), Gaps = 16/90 (17%) Query: 520 EPENKKVWNPEPKPEP--------KPEPKPEPKPEPEPAPASDNVWGAPAPLGGGQPATP 571 E E K + K E K + K E A A P Sbjct: 418 ELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKL-----RAGKASDSQTPDAK 472 Query: 572 PPPPVERFSPAKATAPQPPAAPQPVQEAPK 601 P P K APQ P + K Sbjct: 473 PGNKA---VPGKGQAPQAGTKPNQNKAPMK 499
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 31.8 bits (72), Expect = 0.006 Identities = 26/132 (19%), Positives = 46/132 (34%), Gaps = 15/132 (11%) Query: 267 ASSKENIEWYASH------------ANVRGIGPNKLNQLAHAQFFGDVAGLKAHMLKHAA 314 +E I + + + + LN+ + QFF V L + Sbjct: 37 TDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSV--LDVYGFAVIN 94 Query: 315 SLAPKFERVLEILDSRLSEYGVAKWTSPTGGYFISVDVVPGTASRVVELAKEAGIALTGA 374 + +V+ D++ + VA +P G + VVP T +LA A Sbjct: 95 -MNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLLRQLNDNA 153 Query: 375 GSSFPLHNDPNN 386 G +H +P+N Sbjct: 154 GVGSVVHYEPSN 165
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 52.5 bits (126), Expect = 6e-09 Identities = 34/205 (16%), Positives = 79/205 (38%), Gaps = 9/205 (4%) Query: 216 IIGVAIAAIILIFTFGSLVAAGLPLLIAVIGVGIGSLSITLATAWVSLNNVTPVLAVMLG 275 + + +++ ++ A +P IAV V +G+ +I A S+N +T + ++L Sbjct: 345 FEAIMLVFLVMYLFLQNMRATLIPT-IAVPVVLLGTFAILAAFG-YSINTLT-MFGMVLA 401 Query: 276 LAVGIDYSLFIMFRYRRELL--HLDKEQAAGMAVGTAGSAVVFAGLTVIIALVALAV--- 330 + + +D ++ ++ R ++ L ++A ++ A+V + + + +A Sbjct: 402 IGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGG 461 Query: 331 ANIPFLTYMGLAAAFTVFIAVLIALTMVPALLGALGDKAFAVRLRRKRRT-SPARTLGRK 389 + + + ++VL+AL + PAL L A K T Sbjct: 462 STGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDH 521 Query: 390 WGELVHRAPGVVIAVSVVTLGALTL 414 + G ++ + L L Sbjct: 522 SVNHYTNSVGKILGSTGRYLLIYAL 546
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 34.6 bits (79), Expect = 0.002 Identities = 16/59 (27%), Positives = 22/59 (37%), Gaps = 7/59 (11%) Query: 150 PNTVISAKFDVVGGTTQPEPEPDPAPEPQP-------APEPEPGTSVNPAAPTAVDPAT 201 N S +P P+P P P P AP+P G ++ AA AV+ Sbjct: 560 GNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELSAAANAAVNTGG 618
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 32.1 bits (73), Expect = 0.003 Identities = 46/218 (21%), Positives = 89/218 (40%), Gaps = 30/218 (13%) Query: 36 QARIAEDAGASAVMALERVPADIRAQGGVARMSDPDLIEGIVNAVSIPVMAKARIGHFVE 95 + +I + +A AL+ V + M + + E A I ++K +GH + Sbjct: 91 KGKIENE-QMNAEYALKEVSDMFVSM--FESMDNEYMKE---RAADIRDVSKRVLGHLIG 144 Query: 96 AQI--LESLGVDFIDESEVLSPADYVNHIDKWNFDVPFVCG-ATNLGEALRRITEGAAMI 152 + L ++ + + +E L+P+D + FV G AT++G R + A M Sbjct: 145 VETGSLATIAEETVIIAEDLTPSDTAQ------LNKQFVKGFATDIGG---RTSHSAIMS 195 Query: 153 RSKGE---AGTGDVSEAVKHLRTI-----RGEINRLRSMDEDQLYVAAKEI----QAPYD 200 RS GT +V+E ++H + G + + +E + Y + + + Sbjct: 196 RSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEEKRAAFEKQKQEWA 255 Query: 201 LVREVAATGKLPVTLFVAGGVATPADAALVMQMGAEGV 238 + +T K + +A + TP D V+ G EG+ Sbjct: 256 KLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGI 293
>DPTHRIATOXIN#Diphtheria toxin signature. Length = 567 Score = 1114 bits (2881), Expect = 0.0 Identities = 559/560 (99%), Positives = 560/560 (100%) Query: 1 MSRKLFASILIGALLGIGAPPSAHAGADDVVDSSKSFVMENFSSYHGTKPGYVDSIQKGI 60 +SRKLFASILIGALLGIGAPPSAHAGADDVVDSSKSFVMENFSSYHGTKPGYVDSIQKGI Sbjct: 8 VSRKLFASILIGALLGIGAPPSAHAGADDVVDSSKSFVMENFSSYHGTKPGYVDSIQKGI 67 Query: 61 QKPKSGTQGNYDDDWKGFYSTDNKYDAAGYSVDNENPLSGKAGGVVKVTYPGLTKVLALK 120 QKPKSGTQGNYDDDWKGFYSTDNKYDAAGYSVDNENPLSGKAGGVVKVTYPGLTKVLALK Sbjct: 68 QKPKSGTQGNYDDDWKGFYSTDNKYDAAGYSVDNENPLSGKAGGVVKVTYPGLTKVLALK 127 Query: 121 VDNAETIKKELGLSLTEPLMEQVGTEEFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQ 180 VDNAETIKKELGLSLTEPLMEQVGTEEFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQ Sbjct: 128 VDNAETIKKELGLSLTEPLMEQVGTEEFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQ 187 Query: 181 AKALSVELEINFETRGKRGQDAMYEYMAQACAGNRVRRSVGSSLSCINLDWDVIRDKTKT 240 AKALSVELEINFETRGKRGQDAMYEYMAQACAGNRVRRSVGSSLSCINLDWDVIRDKTKT Sbjct: 188 AKALSVELEINFETRGKRGQDAMYEYMAQACAGNRVRRSVGSSLSCINLDWDVIRDKTKT 247 Query: 241 KIESLKEHGPIKNKMSESPNKTVSEEKAKQYLEEFHQTALEHPELSELKTVTGTNPVFAG 300 KIESLKEHGPIKNKMSESPNKTVSEEKAKQYLEEFHQTALEHPELSELKTVTGTNPVFAG Sbjct: 248 KIESLKEHGPIKNKMSESPNKTVSEEKAKQYLEEFHQTALEHPELSELKTVTGTNPVFAG 307 Query: 301 ANYAAWAVNVAQVIDSETADNLEKTTAALSILPGIGSVMGIADGAVHHNTEEIVAQSIAL 360 ANYAAWAVNVAQVIDSETADNLEKTTAALSILPGIGSVMGIADGAVHHNTEEIVAQSIAL Sbjct: 308 ANYAAWAVNVAQVIDSETADNLEKTTAALSILPGIGSVMGIADGAVHHNTEEIVAQSIAL 367 Query: 361 SSLMVAQAIPLVGELVDIGFAAYNFVESIINLFQVVHNSYNRPAYSPGHKTQPFLHDGYA 420 SSLMVAQAIPLVGELVDIGFAAYNFVESIINLFQVVHNSYNRPAYSPGHKTQPFLHDGYA Sbjct: 368 SSLMVAQAIPLVGELVDIGFAAYNFVESIINLFQVVHNSYNRPAYSPGHKTQPFLHDGYA 427 Query: 421 VSWNTVEDSIIRTGFQGESGHDIKITAENTPLPIAGVLLPTIPGKLDVNKSKTHISVNGR 480 VSWNTVEDSIIRTGFQGESGHDIKITAENTPLPIAGVLLPTIPGKLDVNKSKTHISVNGR Sbjct: 428 VSWNTVEDSIIRTGFQGESGHDIKITAENTPLPIAGVLLPTIPGKLDVNKSKTHISVNGR 487 Query: 481 KIRMRCRAIDGDVTFCRPKSPVYVGNGVHANLHVAFHRSSSEKIHSNEISSDSIGVLGYQ 540 KIRMRCRAIDGDVTFCRPKSPVYVGNGVHANLHVAFHRSSSEKIHSNEISSDSIGVLGYQ Sbjct: 488 KIRMRCRAIDGDVTFCRPKSPVYVGNGVHANLHVAFHRSSSEKIHSNEISSDSIGVLGYQ 547 Query: 541 KTVDHTKVNSKLSLFFEIKS 560 KTVDHTKVNSKLSLFFEIKS Sbjct: 548 KTVDHTKVNSKLSLFFEIKS 567
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 32.2 bits (73), Expect = 0.025 Identities = 17/61 (27%), Positives = 26/61 (42%), Gaps = 8/61 (13%) Query: 1600 ILKGLGGAAGGAAAGFALGGPVGALLGGIAGLLFGGAGQVMNGIAEIKQGRMQESTYKKY 1659 +L + AA +G PV AL+G + G++ +GI E + M E K Sbjct: 374 VLASVSSGISAAATTSLVGAPVSALVGAVTGII--------SGILEASKQAMFEHVASKM 425 Query: 1660 A 1660 A Sbjct: 426 A 426
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 27.1 bits (60), Expect = 0.030 Identities = 11/47 (23%), Positives = 20/47 (42%) Query: 135 GTCREIASACRRLGYEISKTTVHRWAREETISSKTMEDGRVIVSLQE 181 T E+ ++ GY +++ TV R +E + +G SL Sbjct: 20 ETQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSYKYSLPA 66
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 199 bits (508), Expect = 6e-64 Identities = 78/333 (23%), Positives = 148/333 (44%), Gaps = 34/333 (10%) Query: 12 AVAATGLVAAAGCSTTDSGTSASGTSSAAKSDTLKIFATTSYIGDAVKNIAPD-ADLTVM 70 V + C++ T++ LK+ AT S I D KNIA D DL + Sbjct: 8 LVLFLSAIILVACASGKKDTTSG--------QKLKVVATNSIIADITKNIAGDKIDLHSI 59 Query: 71 VGPGGDPHTYQPSTADLEAMQNADAVIWSGLGMEANMIDQLRGLGDKQIAVAEQLPESQL 130 V G DPH Y+P D++ AD + ++G+ +E L + A++ Sbjct: 60 VPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVEN----AKKTENKDY 115 Query: 131 LPWVEEDEHDHDHGDAHEHGHEGEDAHGHHHESQWDPHVWNSTDNWKLVVDQIVKKLSAA 190 A G + G + + + DPH W + +N + I K+LSA Sbjct: 116 F--------------AVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSAK 161 Query: 191 DSANADTYKANGEKYNKQIDEAKAYVQAKIDTIPQDQRTLVSGHDAFRYFGKQFGLEVKA 250 D N + Y+ N ++Y ++D+ + K + IP +++ +V+ AF+YF K +G+ Sbjct: 162 DPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAY 221 Query: 251 TDFVTSDAERSANELEDLATFIVEHHVPVIFQDASANPQAVKSLEENVAKKGGKVKVVDK 310 + ++ E + +++ L + + VP +F ++S + + +K++ ++ Sbjct: 222 IWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIY------A 275 Query: 311 ELYSDSLGADA-PADTYIGALKYNADTIAEAFS 342 ++++DS+ D+Y +KYN D IAE + Sbjct: 276 QIFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLA 308
>adhesinb#Adhesin B signature. Length = 310 Score = 215 bits (549), Expect = 2e-70 Identities = 88/318 (27%), Positives = 158/318 (49%), Gaps = 25/318 (7%) Query: 14 VAALALTGSLVACSTDSASTSATTSAANKALTVFATTGYIGDAVKNIAPD-ADVTIMVGP 72 V L L ACS+ S+T + ++K L V AT I D KNIA D ++ +V Sbjct: 8 VLLLLAFVGLAACSS---QKSSTETGSSK-LNVVATNSIIADITKNIAGDKINLHSIVPV 63 Query: 73 GGDPHTYQPTTQDISKIESSDVVLWSGLHMEAKMLDQL-------KAQGDRQ-AAVAEAI 124 G DPH Y+P +D+ K +D++ ++G+++E K + ++ AV+E + Sbjct: 64 GQDPHEYEPLPEDVKKTSQADLIFYNGINLETGGNAWFTKLVENAKKKENKDYYAVSEGV 123 Query: 125 PEDKRLDWPEPGDNGEKLYDPHVWNSTENWKYVVDAIAKKLSEVDKDNAATYKDNAEKYK 184 G + + DPH W + EN IAK+LSE D N TY+ N + Y Sbjct: 124 D-----VIYLEGQSEKGKEDPHAWLNLENGIIYAQNIAKRLSEKDPANKETYEKNLKAYV 178 Query: 185 KEIDETAAYVKEQIDQIPEQKRILITGHDAFSYFGKQFGVEIHATDFVTSESEMSPAELA 244 +++ KE+ + IP +K++++T F YF K + V + +E E +P ++ Sbjct: 179 EKLSALDKEAKEKFNNIPGEKKMIVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIK 238 Query: 245 ELGKFIAEKKIPTIFQDNLANPQAINSLKETVKAKGWNVEISDKELYADSLGESA-PTDT 303 L + + + K+P++F ++ + + + ++ +K N+ I +++ DS+ E D+ Sbjct: 239 TLVEKLRKTKVPSLFVESSVDDRPMKTV-----SKDTNIPIYA-KIFTDSVAEKGEEGDS 292 Query: 304 YLGVLKYNADAIREALAK 321 Y ++KYN + I E L+K Sbjct: 293 YYSMMKYNLEKIAEGLSK 310
>TACYTOLYSIN#Bacterial thiol-activated pore-forming cytolysin signature. Length = 574 Score = 26.1 bits (57), Expect = 0.014 Identities = 12/37 (32%), Positives = 20/37 (54%) Query: 9 QPVPQPQEATSDTIATQHTSAPLSNDMMLLMAEEIPM 45 QP P+ E T++ + SNDM+ L +E+P+ Sbjct: 52 QPKPESSELTTEKAGQKMDDMLNSNDMIKLAPKEMPL 88
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 49.7 bits (118), Expect = 2e-09 Identities = 49/199 (24%), Positives = 72/199 (36%), Gaps = 9/199 (4%) Query: 2 LNAVG-QAQNILLLGGTSEIGLSIVAEFLAKGPAHVTLAARQDSPRIDAAVAQMKAAGAS 60 +NA G + + + G IG + VA LA AH+ A +P V A A Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEA-VARTLASQGAHIA--AVDYNPEKLEKVVSSLKAEAR 57 Query: 61 EVDVIDFDATDFDKHAEVID-LAWAQGDVDLAIVAFGTL--GDQEQLWQDQKAAVTSAQT 117 + D D E+ + G +D+ + G L G L ++ A S + Sbjct: 58 HAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNS 117 Query: 118 NYTAPVSVGVLLGEKFKEQGHGTIVALSSVAGQRVRRSNFVYGASKAGMDGFYVNLGEAL 177 S V + ++ G+IV + S R S Y +SKA F LG L Sbjct: 118 TGVFNASRSVS--KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLEL 175 Query: 178 RPSGANVVVVRPGQVRTKM 196 +V PG T M Sbjct: 176 AEYNIRCNIVSPGSTETDM 194
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 28.3 bits (63), Expect = 0.025 Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 7/44 (15%) Query: 154 IDGTLRGFVLRVPHLLVPENSPRLGHNISPMRLNGSVVMSPKTV 197 I GT+ GFV VP+++ + H +S + GSV++ P T+ Sbjct: 268 IFGTVAGFVSMVPYMM------KDVHQLSTAEI-GSVIIFPGTM 304
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 46.2 bits (109), Expect = 2e-08 Identities = 15/82 (18%), Positives = 32/82 (39%) Query: 2 RTNKKQQLLATAMDIVESDGLQGLTYDSLSTATGTSKSGLIYHFPSRRALEVELNKYSAS 61 +Q +L A+ + G+ + ++ A G ++ + +HF + L E+ + S S Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 62 LWTQALEDIAGAPPQQLDLPLR 83 + + P LR Sbjct: 69 NIGELELEYQAKFPGDPLSVLR 90
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 136 bits (344), Expect = 2e-37 Identities = 78/414 (18%), Positives = 159/414 (38%), Gaps = 18/414 (4%) Query: 18 HDQRWIFLGIISLGLFVVGADNSVLYTALPALHVHLHTSELEGLWIINAYSLVLAGLLLG 77 H+Q I+L I+S F + VL +LP + + W+ A+ L + Sbjct: 12 HNQILIWLCILS---FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAV 68 Query: 78 TGTLGDKIGHRRMFEIGLSVFAGASILAAVSPNAAT-LITARALLGIGASTMMPASLALL 136 G L D++G +R+ G+ + S++ V + + LI AR + G GA+ PA + ++ Sbjct: 69 YGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAA-AFPALVMVV 127 Query: 137 RITFTDIRERNTAIGIWGAVATLGAALGPVLGGFLLEHYYWGSIFLINVPVVIIALVGTY 196 + R A G+ G++ +G +GP +GG + + +W +L+ +P++ I V Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITV--- 182 Query: 197 FMAPKNRPNPQRSWDFLSSMFAMFFMVGLVLLIKECAHTPISFAMLALGFAFMAVGAALF 256 K R + VG+V + ISF ++++ +F Sbjct: 183 PFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFL------IF 236 Query: 257 WWRHSHLDEPLLRFGVFRNSLFSAGVLAATCAMLILSGTELLTTQRFQLAEGFTPLQAGL 316 + +P + G+ +N F GVL ++G + + + + G Sbjct: 237 VKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGS 296 Query: 317 LSAATA-LAAFPSSIGGGAIVHKVGFRPLISGGFLVMCTGGALTAFSVPHNIFPLLITGL 375 + ++ GG +V + G +++ G + +F + + + I + Sbjct: 297 VIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIV 356 Query: 376 LLCGFGAGMVMSVSSTAVIGSAPSRDSGMASAMEAVSYEFGSLISVALFGSLFS 429 + G + +S+ S + S+ +A+ G L S Sbjct: 357 FVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSF-LSEGTGIAIVGGLLS 409 Score = 33.7 bits (77), Expect = 0.002 Identities = 21/100 (21%), Positives = 40/100 (40%), Gaps = 2/100 (2%) Query: 333 GAIVHKVGFRPLISGGFLVMCTGGALTAFSVPHNIFPLLITGLLLCGFGAGMVMSVSSTA 392 G + ++G + L+ G ++ C G + H+ F LLI + G GA ++ Sbjct: 70 GKLSDQLGIKRLLLFGIIINCFGSVIGFVG--HSFFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 393 VIGSAPSRDSGMASAMEAVSYEFGSLISVALFGSLFSFFY 432 V P + G A + G + A+ G + + + Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIH 167
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 102 bits (257), Expect = 1e-27 Identities = 33/119 (27%), Positives = 57/119 (47%) Query: 8 ATRVLVVDDEPNIVELLKVSLKFQGFEVETAQSGIEALEKARSFQPDAFILDVMMPGMDG 67 +LV DD+ I +L +L G++V + + D + DV+MP + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 68 YELLPKLRADGFEGPVLYLTAKDAVEHRIHGLTIGADDYVTKPFSLEEVITRLRVILRR 126 ++LLP+++ + PVL ++A++ I GA DY+ KPF L E+I + L Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>PF06580#Sensor histidine kinase Length = 349 Score = 38.3 bits (89), Expect = 6e-05 Identities = 25/139 (17%), Positives = 46/139 (33%), Gaps = 36/139 (25%) Query: 381 YPDR---DIDVRSECTDVPVVEGDAARLHQVLTNLVANALKHG----GDSARVTIKLADA 433 + DR + + DV V ++ LV N +KHG ++ +K Sbjct: 236 FEDRLQFENQINPAIMDVQV-------PPMLVQTLVENGIKHGIAQLPQGGKILLKGTKD 288 Query: 434 GSNFAVKVIDDGIGLSEEDASHIFERFYRADSSRARSTGGSGLGLAIVKS-LVESHGGE- 491 ++V + G + +G GL V+ L +G E Sbjct: 289 NGTVTLEVENTGSLALKNTKE------------------STGTGLQNVRERLQMLYGTEA 330 Query: 492 -VSVESEQGHGTTFIVELP 509 + + +QG +V +P Sbjct: 331 QIKLSEKQG-KVNAMVLIP 348
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 32.2 bits (73), Expect = 0.002 Identities = 25/92 (27%), Positives = 36/92 (39%), Gaps = 14/92 (15%) Query: 24 TATSAALLTAQPATASAAPLSSGSSATSSINDQLQTIGQQTRDGAWNL------------ 71 T + A + + +A + + SA S D L+ +QTR+ L Sbjct: 2 TTITTAQIKSTLQSAKQSAANKLHSAGQSTKDALKKAAEQTRNAGNRLILLIPKDYKGQG 61 Query: 72 --RNALISQADALPIEVAAPIKNGIDATVNLF 101 N L+ AD L IEV KNG T +F Sbjct: 62 SSLNDLVRTADELGIEVQYDEKNGTAITKQVF 93
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 45.4 bits (107), Expect = 6e-07 Identities = 36/189 (19%), Positives = 69/189 (36%), Gaps = 28/189 (14%) Query: 513 IDKEIVAAQEKAAAATKEAQEAAEKVEKLTEELAAARKENDELKTQVKESEEAVGDLADK 572 + ++ A + + K++ L E AA EL+ ++ + + K Sbjct: 223 LAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAK 282 Query: 573 VFKL--ENAVTEAKKKATVAEKAVSDA-LAKLQEAESIAEEQKAKAESAAAEAQ------ 623 + L E A EA+K + V +A L+ + E K + E+ + + Sbjct: 283 IKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKIS 342 Query: 624 ------------ALREKLEKLEGSILTAKENSEAEE------SADLSSTARDAADTARRA 665 A RE ++LE +E ++ E DL + +R+A +A Sbjct: 343 EASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDA-SREAKKQVEKA 401 Query: 666 ATDANGALS 674 +AN L+ Sbjct: 402 LEEANSKLA 410 Score = 45.4 bits (107), Expect = 6e-07 Identities = 27/138 (19%), Positives = 50/138 (36%), Gaps = 3/138 (2%) Query: 512 DIDKEIVAAQEKAAAATKEAQEAAEKVEKLTEELAAARKENDELKTQVKESEEAVGDLAD 571 +++K + A + A + + + + L A K + + L Sbjct: 194 ELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEA 253 Query: 572 KVFKLENAVTEAKKKATVAEKAVSDALAKLQEAES---IAEEQKAKAESAAAEAQALREK 628 + LE E +K A + AK++ E+ E +KA E + A R+ Sbjct: 254 EKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQS 313 Query: 629 LEKLEGSILTAKENSEAE 646 L + + AK+ EAE Sbjct: 314 LRRDLDASREAKKQLEAE 331 Score = 45.4 bits (107), Expect = 7e-07 Identities = 40/180 (22%), Positives = 71/180 (39%), Gaps = 34/180 (18%) Query: 511 GDIDKEIVAAQEKAAAATKEAQEAAEKVEKLTEELAAARKEN-------DELKTQVKESE 563 +++K + A + A + + + + L E A ++ L+ + S Sbjct: 263 AELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASR 322 Query: 564 EAVGDLADKVFKLENA--VTEAKKK--------ATVAEKAVSDALAKLQEAESIAE---- 609 EA L + KLE ++EA ++ + A+K + KL+E I+E Sbjct: 323 EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQ 382 Query: 610 ----------EQKAKAESAAAEAQALREKLEKLEGSILTAKENSE---AEESADLSSTAR 656 E K + E A EA + LEKL + +K+ +E AE A L + A+ Sbjct: 383 SLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAK 442 Score = 41.2 bits (96), Expect = 1e-05 Identities = 48/206 (23%), Positives = 78/206 (37%), Gaps = 37/206 (17%) Query: 514 DKEIVAAQEKAAAATKEAQEAAEKVEKLTEELAAARKENDELKTQVKESEEAVGDLADKV 573 + + + A+ + ++ + +KL E+ + L+ + S EA L + Sbjct: 308 NANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEH 367 Query: 574 FKLEN-----------------AVTEAKKK---ATVAEKAVSDALAKL--QEAESIAEEQ 611 KLE A EAKK+ A + AL KL + ES + Sbjct: 368 QKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTE 427 Query: 612 KAKAESAA---AEAQALREKL-------EKLEGSILTAKENSEAEESADLSSTARDAADT 661 K KAE A AEA+AL+EKL KL + + +A+ A Sbjct: 428 KEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQTPDAKPGNK----AVPGKGQ 483 Query: 662 ARRAATDANGALSGQKQNEEK-PAMG 686 A +A T N + K+ + + P+ G Sbjct: 484 APQAGTKPNQNKAPMKETKRQLPSTG 509
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 495 bits (1277), Expect = e-177 Identities = 249/446 (55%), Positives = 327/446 (73%), Gaps = 16/446 (3%) Query: 1 MSAIFQAFRDADLRKKILITIALIILYRIGAQIPSPGVDYASISGRLRELTSDSSSVYSL 60 ++A +AFR DLRKK+L T+A+I++YR+G IP PGVDY ++ +RE + + ++ L Sbjct: 2 LTAFARAFRTPDLRKKLLFTLAIIVVYRVGTHIPIPGVDYKNVQQCVREASG-NQGLFGL 60 Query: 61 INLFSGGALLQLSIFAIGVMPYITASIIVQLLTVVIPKFEELKKEGQSGQAKMDQYTRYL 120 +N+FSGGALLQ++IFA+G+MPYITASII+QLLTVVIP+ E LKKEGQ+G AK+ QYTRYL Sbjct: 61 VNMFSGGALLQITIFALGIMPYITASIILQLLTVVIPRLEALKKEGQAGTAKITQYTRYL 120 Query: 121 TLGLALLQSSGIVALADREQLLGSGVS--VLKEDRNLWTLVMLVLVMSAGAILVMWLGEI 178 T+ LA+LQ +G+VA A L G + D++++T + +V+ M+AG +VMWLGE+ Sbjct: 121 TVALAILQGTGLVATARSAPLFGRCSVGGQIVPDQSIFTTITMVICMTAGTCVVMWLGEL 180 Query: 179 ITERGIGNGMSLLIFAGIATRIPSDGANILS----SSGGVVFAVVLVAVIVLVVGVVFVE 234 IT+RGIGNGMS+L+F IA PS I + G + F V+ +++V VVFVE Sbjct: 181 ITDRGIGNGMSILMFISIAATFPSALWAIKKQGTLAGGWIEFGTVIAVGLIMVALVVFVE 240 Query: 235 QGQRRIPVQYAKRMVGRRQYGGSSTYLPLKVNQAGVIPVIFASSLIYMPVLITQIINSGS 294 Q QRRIPVQYAKRM+GRR YGG+STY+PLKVNQAGVIPVIFASSL+Y+P L+ Q S Sbjct: 241 QAQRRIPVQYAKRMIGRRSYGGTSTYIPLKVNQAGVIPVIFASSLLYIPALVAQFAGGNS 300 Query: 295 HEVSDNWWQRNVIQYLQTPSSWQYIVLYFALIIFFSYFYVSVQYDPNEQADNMKKYGGFI 354 W+ V Q L YIV YF LI+FF++FYV++ ++P E ADNMKKYGGFI Sbjct: 301 ------GWKSWVEQNLTKGDHPIYIVTYFLLIVFFAFFYVAISFNPEEVADNMKKYGGFI 354 Query: 355 PGIRPGRPTAEYLGYVMNRLLFVGALYLGIIAVLPNIALDLGVGASSAGSTPFGGTAILI 414 PGIR GRPTAEYL YV+NR+ + G+LYLG+IA++P +AL VG ++ + PFGGT+ILI Sbjct: 355 PGIRAGRPTAEYLSYVLNRITWPGSLYLGLIALVPTMAL---VGFGASQNFPFGGTSILI 411 Query: 415 MVSVALTTVKQIESQLLQSNYEGLLK 440 +V V L TVKQIESQL Q NYEG L+ Sbjct: 412 IVGVGLETVKQIESQLQQRNYEGFLR 437
>PF05272#Virulence-associated E family protein Length = 892 Score = 36.2 bits (83), Expect = 2e-04 Identities = 14/33 (42%), Positives = 18/33 (54%) Query: 34 LVLVGPSGCGKSTTLRMLAGLEEVNDGRILIGE 66 +VL G G GKST + L GL+ +D IG Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGT 631
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 149 bits (377), Expect = 1e-44 Identities = 76/338 (22%), Positives = 138/338 (40%), Gaps = 43/338 (12%) Query: 2 LVTGGAGFIGSNFVRRVLATRPEYRVTVLDKLT--Y-----AGNAANLDGCDATLVVGDI 54 LVTG AGFIG + +R L ++V +D L Y L D+ Sbjct: 4 LVTGAAGFIGFHVSKR-LLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 55 CDAQLVDRLVADS--DVVVHFAAESHNDNSLVDPSPFVQTNVVGTFTLLEAARRHDVRFH 112 D + + L A + V SL +P + +N+ G +LE R + ++ H Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ-H 120 Query: 113 HV--STDEVFGDLELDDPNRFTEHTPYN-PSSPYSATKAGSDHLVRAWVRSFGLRATISH 169 + S+ V+G P F+ + P S Y+ATK ++ + + +GL AT Sbjct: 121 LLYASSSSVYGLNR-KMP--FSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLR 177 Query: 170 CSNNYGPYQHIEKFIPRQITNILSGLTPKLYGTGEQVRDWIHVDDHNDAVIRILE----- 224 YGP+ + + + +L G + +Y G+ RD+ ++DD +A+IR+ + Sbjct: 178 FFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHA 237 Query: 225 -------------SGRIGQTYIIGADNDHVNNKTVITLICELMGADGFEHVADRPGHDMR 271 S + Y IG ++ V I + + +G + +++ D+ Sbjct: 238 DTQWTVETGTPAASIAPYRVYNIG-NSSPVELMDYIQALEDALGIEAKKNMLPLQPGDVL 296 Query: 272 YAM-DSSTLRAELGWQPRFTDTDTGMREGLLQTIEWYR 308 D+ L +G+ P T +++G+ + WYR Sbjct: 297 ETSADTKALYEVIGFTPE-----TTVKDGVKNFVNWYR 329
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 41.7 bits (98), Expect = 4e-06 Identities = 45/269 (16%), Positives = 86/269 (31%), Gaps = 71/269 (26%) Query: 176 RILITGAHGQLGRALAELLPD-----------------------AELCSHVDFDVVHPPQ 212 + L+TGA G +G +++ L + EL + F Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 213 RSW---------RQYEAIINCAAYNNVDAAEDDRARAWEVNAVAPARLAQIATENNLT-L 262 +E + V + ++ + N + + N + L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 263 VHVSTDFIFDGTTSV--HEETEAPSPLSVYGASKAAGDIAAAVTPKHYVVRTS-----WV 315 ++ S+ ++ + + P+S+Y A+K A ++ A Y + + V Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFTV 181 Query: 316 FGQGG-------NFVETMRSLAQRGIRPNVISDQRGRP--THAADLAAGIVHLL------ 360 +G G F + M G +V + + + T+ D+A I+ L Sbjct: 182 YGPWGRPDMALFKFTKAMLE----GKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHA 237 Query: 361 ------------RSSADYGVYNLSNSGDV 377 S A Y VYN+ NS V Sbjct: 238 DTQWTVETGTPAASIAPYRVYNIGNSSPV 266
>INTIMIN#Intimin signature. Length = 939 Score = 34.7 bits (79), Expect = 0.006 Identities = 46/222 (20%), Positives = 71/222 (31%), Gaps = 15/222 (6%) Query: 2185 IKVKVTYSDKSTDTAVAHVTTVAQTEQSVEVTPGTQTLVDVPGNGDVTVTVPQNSGLKAE 2244 +V VT +A A T +V+ Q V V N V + Sbjct: 556 DQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTN 615 Query: 2245 VAGNL-VTLTSDGSVEGHVTVTYQVKDADGKTTTGKINVQVAKLAEASWPKSASVAAGDS 2303 +G VTL SD V A T +N + + + A D Sbjct: 616 GSGKATVTLKSD-------KPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKA-DK 667 Query: 2304 TVITPEGVDTLPYGTTLSVGSLP---EWATFDQTTGQLTLTADEDATDESTTATITVAYP 2360 T G D + Y + G P + TF T G+L+ + ++ T+ T+T P Sbjct: 668 TTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTP 727 Query: 2361 -DGLT--KQYSVALSVGAATETTADQHDPQWESVVVNGDSVT 2399 L + VA+ V A ++ + G V Sbjct: 728 GKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVK 769
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 26.1 bits (57), Expect = 0.032 Identities = 12/55 (21%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 47 KRGARQGTGTRGRVLAVYSQTLVDTG-EVPTARQIAGEIGITKRMVNIHLKELRD 100 ++ ++ TR +L V + G + +IA G+T+ + H K+ D Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSD 57