>PF04619#Dr-family adhesin Length = 160 Score = 28.0 bits (62), Expect = 0.018 Identities = 9/50 (18%), Positives = 19/50 (38%), Gaps = 3/50 (6%) Query: 35 DDYHPQHVSILSRDRIDAINVR---AEGVLTFGDREFFFIVRDGNWDGTV 81 D++ ++S + D + V + D F+ G+W G + Sbjct: 84 DNFEQGKFFLISDNNRDKLYVNIRPTDNSAWTTDNGVFYKNDVGSWGGII 133
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 50.4 bits (120), Expect = 7e-09 Identities = 24/212 (11%), Positives = 61/212 (28%), Gaps = 10/212 (4%) Query: 139 DAAELRATIEQVNARAVDASWEEYEAEAHRVKARALDALTQALAAREKYDAEQAELARLR 198 + + T++ N + + + + A +E E Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTET---- 1039 Query: 199 AAEAEREQKEREERIAREATERAQREAEARAQAERDAAARREAEALA-----AAETARLN 253 AE +++ + E+ ++ATE + E +A+ + A + +A ET Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099 Query: 254 AELAEQRRIAAEQQAELDRQAAAVREREAAAQAEQRARQAAEQAAAAERQRIADEQAAAA 313 + + + E ++ + + +Q + + A R+ Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPK-VTSQVSPKQEQSETVQPQAEPARENDPTVNIKEP 1158 Query: 314 AEAARREEDMAHKAAINRAALDAFVQGGMPED 345 D A + ++ V + Sbjct: 1159 QSQTNTTADTEQPAKETSSNVEQPVTESTTVN 1190
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 28.7 bits (64), Expect = 0.035 Identities = 28/155 (18%), Positives = 56/155 (36%), Gaps = 23/155 (14%) Query: 30 VFAGAVIAAALSLALFAGGTGLGFLSVSPW---SGEGMSAPAVGIGVIAWMLFTQIVAYG 86 + + GT GF+S+ P+ +S +G +I F ++ Sbjct: 252 LGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVII----FPGTMSVI 307 Query: 87 VGGYVAGRLRTKWADVHGDEI-------------YFRDTAHGFLTWALSAVV-SAALLGS 132 + GY+ G L + ++ I + +T F+T + V+ + + Sbjct: 308 IFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKT 367 Query: 133 AVATLASGAAKAGASAAAGAGTAITATAAAGAGAG 167 ++T+ S + K A AG + T+ G G Sbjct: 368 VISTIVSSSLKQ-QEAGAGMS-LLNFTSFLSEGTG 400
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 23.9 bits (51), Expect = 0.018 Identities = 13/28 (46%), Positives = 17/28 (60%), Gaps = 1/28 (3%) Query: 5 PSPE-DPRPDPNHAPDDPGAPGITPPAP 31 P+PE DP +P+ PD G PG P +P Sbjct: 351 PNPEPDPDLNPDANPDTDGQPGTRPDSP 378
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.6 bits (230), Expect = 5e-24 Identities = 36/118 (30%), Positives = 63/118 (53%), Gaps = 1/118 (0%) Query: 2 RILIAEDDSILADGLSRSLRHNGYAVDAVRDGLAADSALAAQAFDLLILDLGLPQLAGLE 61 IL+A+DD+ + L+++L GY V + +AA DL++ D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLRRLRARNSALPVLILTAADSIEQRVKGLDLGADDYMAKPFALSE-LEARVRALTRR 118 +L R++ LPVL+++A ++ +K + GA DY+ KPF L+E + RAL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>PF06580#Sensor histidine kinase Length = 349 Score = 41.4 bits (97), Expect = 5e-06 Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 19/77 (24%) Query: 390 LLNNLVDNALRY----TPRGGHITVRVQALDGQAVLEVEDSGPGIALEERERVFDRFYRV 445 L+ LV+N +++ P+GG I ++ +G LEVE++G +E Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE--------- 309 Query: 446 LGTLSDGSGLGLAIVRE 462 +G GL VRE Sbjct: 310 ------STGTGLQNVRE 320
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 40.6 bits (95), Expect = 1e-05 Identities = 53/280 (18%), Positives = 100/280 (35%), Gaps = 27/280 (9%) Query: 46 GFIFALLAFAAGFAVRPFGALVFGRLGDLVGRKYTFLVTIVIMGLSTFLVGVLPSYASIG 105 G + AL A FA P G L D GR+ LV++ + ++ P Sbjct: 46 GILLALYALMQ-FACAPVL----GALSDRFGRRPVLLVSLAGAAVDYAIMATAPFL---- 96 Query: 106 LAAPAILIVLRLLQGLALGGEYGGAATYVAEHAPHGRRGFYTSWIQTTATLGLFLSLLVI 165 +L + R++ G+ G A Y+A+ R + ++ G+ Sbjct: 97 ----WVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAG---- 147 Query: 166 LGIRTFMGEDDFKAWGWRIPFLISVVLLGISVWIRLQLNESPTFQRMKDEGKGSKAPIAE 225 + MG + PF + L G++ L + + + P+A Sbjct: 148 PVLGGLMGG-----FSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLAS 202 Query: 226 SFGQWKNLKVVLLALLGLTAGQAVVWYTGQFYALFFLTQTLKVDANTANIMIAIALLIGT 285 +W V+ AL+ + +V + F DA T I +A ++ + Sbjct: 203 F--RWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHS 260 Query: 286 PF-FVIFGALSDKIGRKPIIMAGCLIAAATYFPIFQGITH 324 +I G ++ ++G + +M G +IA T + + T Sbjct: 261 LAQAMITGPVAARLGERRALMLG-MIADGTGYILLAFATR 299 Score = 33.6 bits (77), Expect = 0.002 Identities = 14/47 (29%), Positives = 24/47 (51%) Query: 270 ANTANIMIAIALLIGTPFFVIFGALSDKIGRKPIIMAGCLIAAATYF 316 I++A+ L+ + GALSD+ GR+P+++ AA Y Sbjct: 42 TAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYA 88
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 30.8 bits (69), Expect = 0.001 Identities = 10/49 (20%), Positives = 15/49 (30%), Gaps = 2/49 (4%) Query: 83 ARFIQEIYAAFGEI--LGELHECSYVHVIDARAAAYGYGGKTQEYRHQH 129 F I L EL + H + R G G+ + Y+ Sbjct: 480 GTFFTYERTPEESIYTLEELFRHEFTHYLQGRYVVPGMWGQGEFYQEGV 528
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 168 bits (428), Expect = 5e-47 Identities = 94/435 (21%), Positives = 167/435 (38%), Gaps = 62/435 (14%) Query: 5 LRNVAIIAHVDHGKTTLVDQLLRQSGTFRENQALTE--RVMDSNDLEKERGITILAKNCA 62 + N+ ++AHVD GKTTL + LL SG E ++ + D+ LE++RGITI + Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 63 VEYEGTHINIVDTPGHADFGGEVERVLSMVDGVLLLVDAVEGPMPQTIFVTRKALALGLK 122 ++E T +NI+DTPGH DF EV R LS++DG +LL+ A +G QT + +G+ Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 123 PIVVVNKVDRPGART-------------DFVINATFDLFDKLGATDEQL----------- 158 I +NK+D+ G + VI +L+ + T+ Sbjct: 123 TIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGN 182 Query: 159 -DFPVVYASG--LSG---YAGLTPDVREGDMRPLF--------------EAILQHVPQRD 198 D Y SG L + + P++ E I Sbjct: 183 DDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSST 242 Query: 199 DDPNGPLQMQIISLDYNSYVGKIGVGRINRGRMRPGMEVAYKFGPEGQGGRGRINQVLKF 258 L ++ ++Y+ ++ R+ G + V + + +I ++ Sbjct: 243 HRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRIS-----EKEKIKITEMYTS 297 Query: 259 HGLERIVVDEAEAGDIVLINGIEDLGIGCTVTDPVTQDVLPMLRIDEPTLTMNFMVNTSP 318 E +D+A +G+IV++ E L + + D + P L + Sbjct: 298 INGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQ 356 Query: 319 LAGREGKFVTSRQLRDRLDRELKSNVALRVRDTGDDTVFEVSGRGELHLTILLETMRRE- 377 L D L S+ LR +S G++ + + ++ + Sbjct: 357 QREM---------LLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKY 407 Query: 378 GYELAVSRPRVVFKE 392 E+ + P V++ E Sbjct: 408 HVEIEIKEPTVIYME 422 Score = 33.7 bits (77), Expect = 0.003 Identities = 17/100 (17%), Positives = 32/100 (32%), Gaps = 1/100 (1%) Query: 387 RVVFKEVDGVKCEPFESLTIDVEDAHQGGVMEELGRRKGDLQDMQPDGRGRTRLEYLIPA 446 V K+ EP+ S I + + + ++ D Q L IPA Sbjct: 525 EQVLKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQL-KNNEVILSGEIPA 583 Query: 447 RGLIGFQNEFLTLTRGTGLMSHIFHEYAPIKEGSIGERRN 486 R + ++++ T G + Y + + R Sbjct: 584 RCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRR 623
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 76.8 bits (189), Expect = 2e-16 Identities = 69/277 (24%), Positives = 94/277 (33%), Gaps = 76/277 (27%) Query: 525 VMGHVDHGKTSLLDYIRRAKVAAGEAG------------------GITQHIGAYHVETER 566 V+ HVD GKT+L + + A E G GIT G + E Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 567 GMVTFLDTPGHEAFTAMRARGAKATDIVILVCAADDGVMPQTREAIHHAKAAGVPMVVAM 626 V +DTPGH F A R D IL+ +A DGV QTR H + G+P + + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 627 TKIDKPSANPERVKQ--------------------------------------------- 641 KID+ + V Q Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 642 ------ELVAEEVVPEEYGG--DVPFVPV---SAKTGEGIDALLENVLLQAELLELKAPV 690 L A E+ EE + PV SAK GID L+E + + Sbjct: 188 KYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT--NKFYSSTHRG 245 Query: 691 DAQAKGLVIEARLDKGRGPVATILVQSGTLHRGDVVL 727 ++ G V + + R +A I + SG LH D V Sbjct: 246 QSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVR 282
>cloacin#Cloacin signature. Length = 551 Score = 31.6 bits (71), Expect = 0.009 Identities = 28/118 (23%), Positives = 36/118 (30%), Gaps = 10/118 (8%) Query: 431 GEANGNRKGGKPTGGRGQAGAGGKSGGRGGKAGGGKARGVRAAAAGSAGAPEATVGAGRK 490 G+ G+ G T G G G G G G G + GS G+G Sbjct: 4 GDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHG 63 Query: 491 PAGAKPGGKPAGARGGNAGRGNKPAGAGRAGNKAEGARAGGNKGPGAGGKPRAARGGS 548 G GN+G G+ G A PGAGG + G+ Sbjct: 64 NGGG----------NGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGA 111
>SOPEPROTEIN#Salmonella type III secretion SopE effector protein signature. Length = 239 Score = 27.8 bits (61), Expect = 0.038 Identities = 14/40 (35%), Positives = 21/40 (52%) Query: 16 PAFAQNVATVNGKAIPQKSLDQFVKLLVSQGATDSPQLRE 55 PA+A A+ K+ DQ LL+S+G +P L+E Sbjct: 103 PAYASQTREAILSAVYSKNKDQCCNLLISKGINIAPFLQE 142
>PF04183#IucA / IucC family Length = 580 Score = 27.5 bits (61), Expect = 0.045 Identities = 16/72 (22%), Positives = 21/72 (29%), Gaps = 27/72 (37%) Query: 100 WRLRVRTWAPDDEFPMV-ASLMEC----------------WPAVGWFER----------E 132 WR W DE P++ A+LMEC A W + Sbjct: 351 WRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYH 410 Query: 133 AFDLYGIVFEGH 144 YG+ H Sbjct: 411 LLCRYGVALIAH 422
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 24.8 bits (54), Expect = 0.037 Identities = 10/30 (33%), Positives = 13/30 (43%) Query: 4 QQYFPVLLFIVVATLIGFALLTAGSLLGPR 33 + + IV TL+ F LT SL R Sbjct: 5 RSSLVWCVLIVCLTLLIFTYLTRKSLCEIR 34
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 101 bits (253), Expect = 2e-26 Identities = 84/388 (21%), Positives = 141/388 (36%), Gaps = 58/388 (14%) Query: 1 MKKTLLAAALLAGFAGVAQAETSVTLYGIIDTGIGYNK-ISGAGDAKNGSKIGMINGVQN 59 MKK+L+A L A A VTLYG I G+ ++ ++ G + G V Sbjct: 1 MKKSLIALTLAAL---PVAAMADVTLYGTIKAGVETSRSVAHNGAQAASVETGT-GIVDL 56 Query: 60 GSRWGLRGSEDLGDGLRAVFQLESGFDSGNGKSGQNGRLFGRQATVGLASDSWGQLDFGR 119 GS+ G +G EDLG+GL+A++Q+E +G + RQ+ +GL +G+L GR Sbjct: 57 GSKIGFKGQEDLGNGLKAIWQVEQK----ASIAGTDSGWGNRQSFIGLKGG-FGKLRVGR 111 Query: 120 QTNIASKYFGSIDPFGAGFNVANIGTGMSAANTQRYDNMVMYQTPSFSGFQFGVGYSFSA 179 ++ G I+P+ + ++ A + V Y +P F+G V Y+ + Sbjct: 112 LNSVLKDT-GDINPW---DSKSDYLGVNKIAEPEARLISVRYDSPEFAGLSGSVQYALND 167 Query: 180 DEGNADGSTKADPDRVGFKTADNVRAITTGLRYVNGPLNVALTYDQLNASHNQAQGEVDA 239 + G + + G Y NG V Q ++ Sbjct: 168 NAGRHNS-----------------ESYHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIE- 209 Query: 240 TPRSYMIGGSYDFEVVKLALAYARTTDGWFATSNPAGASGTITVDGTSRKLGFGANQFAD 299 + + + YD + + ++ + D A S + + A +F + Sbjct: 210 KYQIHRLVSGYDNDALYASV-AVQQQD---AKLVEENYSHNSQTEVAAT----LAYRFGN 261 Query: 300 GFKANSYLLGLSAPIGGASSLFGSWQRVDPSNNKLTGDDATMNVFSAGYTYDLSKRTNLY 359 SY G + + G YD SKRT+ Sbjct: 262 VTPRVSYAHGFKGSFDAT------------------NYNNDYDQVVVGAEYDFSKRTSAL 303 Query: 360 AYGSYSKNYAFNDGVKATAVGVGLRHRF 387 + + +TA GVGLRH+F Sbjct: 304 VSAGWLQEGKGESKFVSTAGGVGLRHKF 331
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.1 bits (166), Expect = 2e-16 Identities = 33/150 (22%), Positives = 55/150 (36%), Gaps = 6/150 (4%) Query: 8 ADRNERLSALRRQMILDAAQRVFERDGLEKTTIRAIAKEAGCTTGAIYPWFAGKEILYGA 67 A + ++ + RQ ILD A R+F + G+ T++ IAK AG T GAIY F K L+ Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 68 LLDESLQRLHAHLQAATADC--APAAAARQAILAFFGYYAERRTDFSLGLYLFQ---GLG 122 + + S + A P + R+ ++ L +F +G Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 123 PRGLGRDMDEQLNGRLRQ-CVDVLGQALAR 151 + + L L + Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEA 151
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 32.5 bits (73), Expect = 0.009 Identities = 31/109 (28%), Positives = 46/109 (42%), Gaps = 5/109 (4%) Query: 310 GAMARYLASLTASTVANARAALGAKAQAAAALEQAVANEKAAAAAAGQAAAQVRLGGSLA 369 G A Y L +++ + + AA A +A A KA AA +A + Sbjct: 183 GLTAAYNVKLFTEAISSLQIRMN-TLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQ 241 Query: 370 ASTAAANAHRAAQTALAGAQRAATAAGTGLVAMLGGPAGIIGLLATAAA 418 A+ AAN + A A ATAAG GL+ + G A + ++ A A Sbjct: 242 AAIRAANTY--AMPANGSV--VATAAGRGLIQVAQGAASLAQAISDAIA 286
>INTIMIN#Intimin signature. Length = 939 Score = 33.9 bits (77), Expect = 0.001 Identities = 19/43 (44%), Positives = 26/43 (60%) Query: 201 WTSSNPSMAMVNQVSGQITAVAAGSVTITAASSVAPAVTDTIA 243 W S+NP++A V+ SGQ+T G+ TI+ SS T TIA Sbjct: 795 WRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTIA 837
>OUTRSURFACE#Outer surface protein signature. Length = 273 Score = 28.3 bits (63), Expect = 0.044 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 15/86 (17%) Query: 45 AGLRHNVDSIKSKARILIAWVDEAESVSKIAWQKLAPTVRESGSEIWITWNPEKDGSPTD 104 +G+ KSKA++ IA + +SK ++ +E G + KD + TD Sbjct: 73 SGVLEGTKDDKSKAKLTIA-----DDLSKTTFE----LFKEDGKTLVSRKVSSKDKTSTD 123 Query: 105 ERFRKNPPTSAKIV------ELNYTD 124 E F + SAK + +L YT+ Sbjct: 124 EMFNEKGELSAKTMTRENGTKLEYTE 149
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 23.5 bits (50), Expect = 0.040 Identities = 12/42 (28%), Positives = 19/42 (45%), Gaps = 2/42 (4%) Query: 7 DLARRIFEDPSEKAVMDLFQELCAERDRMAWANEGRESATMH 48 AR +F DPS+ ++ +EL +D + ES H Sbjct: 113 RQARSLFPDPSDLVLV--LRELLRRKDLEEIVRKKLESLLKH 152
>PF07520#Virulence protein SrfB Length = 1041 Score = 28.8 bits (64), Expect = 0.021 Identities = 12/58 (20%), Positives = 14/58 (24%) Query: 112 IQILAVSLDPNYSGDRVGAFIYGLADTIIAAHNGKTRLYATDALDGQRVYNAARNVEA 169 IQIL D N R FI H L D + + Sbjct: 27 IQILDFGFDINALDIRSFRFIERPEGAAEGRHRTLYPLTGEAERDAPILAATTPEDDE 84
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.6 bits (64), Expect = 0.027 Identities = 11/38 (28%), Positives = 17/38 (44%), Gaps = 1/38 (2%) Query: 27 LKLAVNAALTLQRPLLIKGEPGTGKTMLAEEVARALDR 64 ++ T L+I GE GTGK ++A + R Sbjct: 150 YRVLARLMQT-DLTLMITGESGTGKELVARALHDYGKR 186
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.1 bits (78), Expect = 1e-04 Identities = 16/68 (23%), Positives = 28/68 (41%), Gaps = 2/68 (2%) Query: 87 AWPAYKYSVEHSVYVDGRFRGRGLGEALMRVLIERARANQVHLMIGGIDAANQGSIKLHE 146 W Y +E + V +R +G+G AL+ IE A+ N ++ N + + Sbjct: 85 NWNGYAL-IED-IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYA 142 Query: 147 KLGFVHAG 154 K F+ Sbjct: 143 KHHFIIGA 150
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 141 bits (357), Expect = 3e-39 Identities = 84/388 (21%), Positives = 141/388 (36%), Gaps = 77/388 (19%) Query: 2 SKIIGIDLGTTNSCVAVMDGGQVKIIENAEGART----TPSIVAYMDDGETLVGAPAKRQ 57 S + IDLGT N+ + V G V + R +P VA VG AK+ Sbjct: 10 SNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVA-------AVGHDAKQM 62 Query: 58 AVTNPKNTLYAVKRLIGRKFEEKAVQKDINLMPYAIVKADNGDAWVEVRGKKMAPPQVSA 117 P N + A++ + + +A V+ Sbjct: 63 LGRTPGN-IAAIRPM---------------------------------KDGVIADFFVTE 88 Query: 118 DVLRK-MKKTAEDYLGEEVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAA 176 +L+ +K+ + ++ VP +R+A +++ + AG +I EP AAA Sbjct: 89 KMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAA 148 Query: 177 LAFGLDKTEKGDRKIAVYDLGGGTFDVSIIEIADVDGEKQFEVLSTNGDTFLGGEDFDQR 236 + GL +E V D+GGGT +V++I + V + +GG+ FD+ Sbjct: 149 IGAGLPVSE--ATGSMVVDIGGGTTEVAVISLNGV---------VYSSSVRIGGDRFDEA 197 Query: 237 IIDYIIGEFKKEQGVDLSKDVLALQRLKEAAEKAKIELSSS----QQTEINLPYITADAS 292 II+Y+ + G + AE+ K E+ S+ + EI + Sbjct: 198 IINYVRRNYGSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEG 244 Query: 293 GPKHLNLKITRAKLEALVEELIERTIEPCRVAIKDAGVKVSDIDD--VILVGGMTRMPKV 350 P+ L + LEAL E L + SDI + ++L GG + + Sbjct: 245 VPRGFTLN-SNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNL 303 Query: 351 QEKVKEFFGKDPRKDVNPDEAVAAGAAI 378 + E G +P VA G Sbjct: 304 DRLLMEETGIPVVVAEDPLTCVARGGGK 331
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.006 Identities = 18/126 (14%), Positives = 41/126 (32%), Gaps = 6/126 (4%) Query: 17 DADAAPAAQDAAQAELNELRAQLDAAQATVNEQQDQLLRVRAEAENVRRRAQEEVSKARK 76 +AD QA L + R Q+ + + ++L ++ E + EE Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSI----ELNKLPELKLPDEPYFQNVSEEEVLRLT 188 Query: 77 FGIESFAESLVPVKDSLEAALAQADQTVDTLREGVEVTLKQLAAAFERNLLKEIAPVQGD 136 I+ + K E L + T+ + + + E++ L + + + Sbjct: 189 SLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARIN--RYENLSRVEKSRLDDFSSLLHK 246 Query: 137 KFDPHL 142 + Sbjct: 247 QAIAKH 252
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 34.4 bits (79), Expect = 3e-04 Identities = 18/62 (29%), Positives = 25/62 (40%), Gaps = 9/62 (14%) Query: 40 DTARNTGLTEYPVATYEEIGKDAS-----LAVVMGGDGTVL----GAARHLAPYGVPVVG 90 + A N GLT PV ++ +S L + + GDG L G PVVG Sbjct: 24 EFADNLGLTLLPVEPSTQVNAASSHTKPPLVIFLSGDGGWATLDKAVGGILQQQGWPVVG 83 Query: 91 IN 92 + Sbjct: 84 WS 85
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 35.4 bits (81), Expect = 6e-04 Identities = 51/262 (19%), Positives = 89/262 (33%), Gaps = 36/262 (13%) Query: 129 HAHQSLMRPEAQRDLLDAHGGHGELRQGVAQAWKQWRALARQLELAEKDAAGLAAERERL 188 HA+ + M+ E +R L A+A ++ R A E A ++A E ER Sbjct: 117 HANNAAMQAEDERLRL-------------AKAEEKARKEAEAAEKAFQEAEQRRKEIERE 163 Query: 189 QWQVDELDRLGLAPDEWDALQSEHTRLSHSQSLLDGATQILDALDGEGDSAHHRLTAANQ 248 + + + +L A + LS ++ A + L A E + N Sbjct: 164 KAETERQLKLAEA------EEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLNS 217 Query: 249 RIQQMLRHD----TGLQGIYDELESARIAISEAVSDLNNYVSRVDLDPRRLADVEARLSA 304 R+ + L G +EL A E + R + + EA Sbjct: 218 RLSSSIHARDAEMKTLAGKRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRR 277 Query: 305 V-----FETARKFRTEPEALCALRDSLHAELSALQAAADIDALRAQAQAAQAQYDAAAAK 359 V E +K T E + ++A+++ +Q A I + A A+ A Sbjct: 278 VGAGKIREEKQKQVTASE---TRINRINADITQIQKA--ISQVSNNRNAGIARVHEAEEN 332 Query: 360 LTTARRKVAKDLGKQVTQAMQT 381 L ++ L Q+ A+ Sbjct: 333 L---KKAQNNLLNSQIKDAVDA 351
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 28.3 bits (63), Expect = 0.012 Identities = 11/49 (22%), Positives = 21/49 (42%), Gaps = 5/49 (10%) Query: 30 QRHLSAEDVYRALIGENVEIG----LATVYRVLTQFEQAGILARSQFDS 74 + L+ DV L +N +I T Q + I+A+++F + Sbjct: 195 KYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNAS-IIAQTRFKN 242
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 121 bits (306), Expect = 4e-32 Identities = 77/391 (19%), Positives = 164/391 (41%), Gaps = 16/391 (4%) Query: 26 FVVVLDTTITNVAMPTISGFLGVSTTEGTWIITAYAVAEAITVPLTGWLSRQFGQVKVFI 85 F VL+ + NV++P I+ W+ TA+ + +I + G LS Q G ++ + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 86 VSVALFVLFSVCCGLSWSLPSLVLF-RVLQGFAGGPLIPLSATLLLSVFPEKKSNVALAL 144 + + SV + S SL++ R +QG L ++ P++ A L Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 145 WGMMTVVAPIIGPILGGLISDNWRWQWVFYINIGFGLLVGLGSWWVLKGRETKIQRSRLD 204 G + + +GP +GG+I+ W ++ I + + + + + ++ + D Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM---ITIITVPFLMKLLKKEVRIKGHFD 200 Query: 205 GVGLTLLVVFVTAFQVMLDKGRELDWFSSNVILTCAIVSAISLILFIIWELTDEQPVIDL 264 G+ L+ V + F + F+++ ++ IVS +S ++F+ P +D Sbjct: 201 IKGIILMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDP 250 Query: 265 SVLKSRNWVVSTITLCLMYGIFFGNIVLTPLWLQQWMGYTATWAGLATAPMGILAV-VTS 323 + K+ +++ + +++G G + + P ++ + G G ++V + Sbjct: 251 GLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFG 310 Query: 324 PLVGRLLPKVDPRLLVTYGMGVLAASFVMRALMTSQVDFMSVAIPMFVLGAGIPACVITL 383 + G L+ + P ++ G+ L+ SF+ + + + I +FVLG G+ + Sbjct: 311 YIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG-GLSFTKTVI 369 Query: 384 TSLGVSDLPPDRIAGGSGLQNFLRVLCMAIG 414 +++ S L G L NF L G Sbjct: 370 STIVSSSLKQQEAGAGMSLLNFTSFLSEGTG 400
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 97.2 bits (242), Expect = 4e-24 Identities = 75/413 (18%), Positives = 134/413 (32%), Gaps = 74/413 (17%) Query: 25 KKMLIAFGAALLVVLACYFIWLIF--------FAGKTVTTDNAYTAVEVAQVTPLVSGPV 76 + ++ L FI + GK + + + P+ + V Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKE------IKPIENSIV 107 Query: 77 KEVKVVDTQAVHAGDVLVVLDDTDAKIALEQAEADLGRAR-------------------- 116 KE+ V + ++V GDVL+ L A+ + ++ L +AR Sbjct: 108 KEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPE 167 Query: 117 ------------------RQVRQIVANDTTLAGQMDQRAAAIQSAQHE---VTRARSRYD 155 R I +T Q Q+ + + E V +RY+ Sbjct: 168 LKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYE 227 Query: 156 KAVLDEKRR----RNLVEGGAVSAQDFTDSQAELREATAALGQAEANLKAAGAASVSAKG 211 EK R +L+ A++ + + + EA L ++ L+ + +SAK Sbjct: 228 NLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKE 287 Query: 212 SRQANEALF----LDSTVETNPIVVTAKAHADQARVNLDRTVLRAPVDGIVTQRSV-DIG 266 Q LF LD +T + + +V+RAPV V Q V G Sbjct: 288 EYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEG 347 Query: 267 QQVQAGMRLMNIVPIQQIY-VDANFKEGQLRNVKPGQKARLTADIYGDDVEYDGRVEGFA 325 V LM IVP V A + + + GQ A + + + Y G + G Sbjct: 348 GVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAF-PYTRY-GYLVG-- 403 Query: 326 GGSGSALSVIPAQNATGNWIKVVQRLPVRIRLDPEQLKKHPLRIGLSMEVSVD 378 + I + +V + + I + + + M V+ + Sbjct: 404 -----KVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAE 451
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 29.9 bits (67), Expect = 0.024 Identities = 27/125 (21%), Positives = 35/125 (28%), Gaps = 8/125 (6%) Query: 342 ERPAPFAGTVAIDAAPSD----QDADASASTPTIASKPPAENQEPPLWENMGGAAAPARP 397 E PAP AP+D Q P EPP + +P Sbjct: 42 ELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKP 101 Query: 398 PAAQTSPDVVEDLLEMVGMADPSNASQDGEAASVDAPAPTSEAAMSATA----APPPPVS 453 VE V + AS A + T+ AA S + P +S Sbjct: 102 KPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALS 161 Query: 454 MAAPQ 458 PQ Sbjct: 162 RNQPQ 166
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 28.9 bits (64), Expect = 0.010 Identities = 15/30 (50%), Positives = 21/30 (70%), Gaps = 1/30 (3%) Query: 7 ELPPPAYQIAAQQAGVPSPVLFAVALQESG 36 +L PA Q+A+QQ+GVP ++ A A ESG Sbjct: 155 QLSLPA-QLASQQSGVPHHLILAQAALESG 183
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 27.2 bits (60), Expect = 0.014 Identities = 10/29 (34%), Positives = 13/29 (44%) Query: 52 GETDEATRQANDVAIGADDPMISHFRITP 80 GE D D G D P+ F++TP Sbjct: 108 GEVDSKGEIKADSGGGTDAPIRKPFKLTP 136
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 33.3 bits (76), Expect = 0.001 Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 12/46 (26%) Query: 160 SQSELARRLAADGFPVQQSHISRM------------NDAVRYLLPA 193 +Q EL L DG+ V Q+ +SR N + +Y LPA Sbjct: 21 TQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSYKYSLPA 66
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 41.5 bits (97), Expect = 2e-07 Identities = 21/86 (24%), Positives = 35/86 (40%), Gaps = 8/86 (9%) Query: 60 ALAGYRFQENLI--------YGRFLYVDDLVVTERSRGARHGASLLQALERMAREAGCAK 111 A Y + N I + + ++D+ V + R G +LL A+E Sbjct: 66 AAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCG 125 Query: 112 LVLDTGLGNALAQRFYFRQGLLTGAM 137 L+L+T N A FY + + GA+ Sbjct: 126 LMLETQDINISACHFYAKHHFIIGAV 151
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.009 Identities = 15/94 (15%), Positives = 36/94 (38%), Gaps = 10/94 (10%) Query: 34 MEPEHWMAELLQAESAERQVRAQANQMKAARFPVHRDLLGFDFAASPVDRALVERLHQGD 93 + + + +A + + R + ++ L+G S + + L + Sbjct: 106 FDLTELIGIIGRALAEPK--RRPSKLEDDSQDG--MPLVG----RSAAMQEIYRVLAR-- 155 Query: 94 FIHTPENVVLVGGPGTGKTHLATAIGIQAVRQHR 127 + T +++ G GTGK +A A+ R++ Sbjct: 156 LMQTDLTLMITGESGTGKELVARALHDYGKRRNG 189
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 26.6 bits (58), Expect = 0.014 Identities = 12/36 (33%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 5 YTEEQII-GFLKQAAAGTPVKELCRKHGFSDASFYL 39 EQ+I G L+ G P+K+L + +DA +L Sbjct: 203 NGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFL 238
>PF07132#Harpin protein (HrpN) Length = 356 Score = 31.2 bits (70), Expect = 0.011 Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 1/67 (1%) Query: 330 MGGMMG-GMDHGGSGQAMEMTGMTGMTGMTGMTGMGSGSMSGMDHGAMAGMNHGAMNHGG 388 MG MMG G+ G G + G+ G G+ G S+ A+ G GA+ G Sbjct: 61 MGSMMGGGLGGGLGGLGSSLGGLGGGLLGGGLGGGLGSSLGSGLGSALGGGLGGALGAGM 120 Query: 389 MAMDHSQ 395 AM+ S Sbjct: 121 NAMNPSA 127
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.2 bits (203), Expect = 3e-20 Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 3/136 (2%) Query: 2 KLLVVEDENKTADYVRQGLMEAGFVVDLARNGLDGHHLAMGETYDLVVLDVMLPDVDGWR 61 +LV +D+ + Q L AG+ V + N DLVV DV++PD + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 IVRALRDAGKQVPVLFLTARGGVDDRVKGLELGADDYLVKPFAFSELLARVRTLL---RR 118 ++ ++ A +PVL ++A+ +K E GA DYL KPF +EL+ + L +R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 119 GSAPSQPDRIQVADLV 134 + + D LV Sbjct: 125 RPSKLEDDSQDGMPLV 140
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.0 bits (62), Expect = 0.014 Identities = 10/52 (19%), Positives = 23/52 (44%), Gaps = 6/52 (11%) Query: 91 ISVLPPRQGRGIGSRLMEQALSELRAMQAAGCVL------LGDPTYYTRFGF 136 I+V + +G+G+ L+ +A+ + G +L + +Y + F Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 124 bits (312), Expect = 4e-36 Identities = 49/119 (41%), Positives = 79/119 (66%), Gaps = 5/119 (4%) Query: 3 LSKFFMDRPIFAAVLSIVIFVSGLLAIPALPISEYPK-----VVVRAVYPGANPKVIAET 57 ++ FF+ RPIFA VL+I++ ++G LAI LP+++YP V V A YPGA+ + + +T Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 58 VATPLEEQINGVEGMMYIKSVAGSDGVLVTTVTFRSGINADDATVRVQNRVAQAQARLP 116 V +E+ +NG++ +MY+ S + S G + T+TF+SG + D A V+VQN++ A LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLP 119
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.4 bits (123), Expect = 2e-09 Identities = 25/121 (20%), Positives = 48/121 (39%), Gaps = 5/121 (4%) Query: 2 SGYVERVAYREGDEVKKGDVLFMIDARSYRAELARAQAQLTRARSEAGRSR--SEAQRAK 59 + V+ + +EG+ V+KGDVL + A A+ + Q+ L +AR E R + S + Sbjct: 104 NSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELN 163 Query: 60 VLVEQQAVSTEAWEQRRAADESAQ---AEVQAAQAAVETAQLNLERTQVRSPINGRASRA 116 L E + ++ + + Q + + Q L + R+ +R Sbjct: 164 KLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARI 223 Query: 117 R 117 Sbjct: 224 N 224 Score = 34.0 bits (78), Expect = 6e-04 Identities = 13/82 (15%), Positives = 34/82 (41%) Query: 25 IDARSYRAELARAQAQLTRARSEAGRSRSEAQRAKVLVEQQAVSTEAWEQRRAADESAQA 84 ++ RAE A++ R + + +S L+ +QA++ A ++ A Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVN 266 Query: 85 EVQAAQAAVETAQLNLERTQVR 106 E++ ++ +E + + + Sbjct: 267 ELRVYKSQLEQIESEILSAKEE 288
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 29.5 bits (66), Expect = 0.003 Identities = 15/34 (44%), Positives = 19/34 (55%), Gaps = 5/34 (14%) Query: 14 GRTFGRGWRAY--ARGERRAS---NWLVSKGVPA 42 G T G AY ERRA ++L+SKG+PA Sbjct: 259 GYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPA 292
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 25.5 bits (55), Expect = 0.039 Identities = 12/27 (44%), Positives = 12/27 (44%) Query: 47 TYTMPDEGGASLRAAGWRLIGARGGGA 73 TY MP G AAG LI G A Sbjct: 249 TYAMPANGSVVATAAGRGLIQVAQGAA 275
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 27.2 bits (60), Expect = 0.007 Identities = 13/29 (44%), Positives = 18/29 (62%) Query: 1 MKKLTTLTTLIALAAALSAPAWAATKTVT 29 MKK+ L+ L A+ A + + AAT TVT Sbjct: 1 MKKIACLSALAAVLAFTAGTSVAATSTVT 29
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 28.7 bits (64), Expect = 0.032 Identities = 13/46 (28%), Positives = 20/46 (43%), Gaps = 12/46 (26%) Query: 165 SQSELARRLAADGFPVQRSHITRMAD---AVR---------YLLPA 198 +Q EL L DG+ V ++ ++R V+ Y LPA Sbjct: 21 TQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSYKYSLPA 66
>PF02370#M protein repeat Length = 168 Score = 30.5 bits (68), Expect = 0.009 Identities = 21/97 (21%), Positives = 43/97 (44%), Gaps = 3/97 (3%) Query: 36 EEMKALGIEGDTPRDTVATLVAQVKQLRTELQTALSDNKSQREENQRLRQRENSIDQRIN 95 + +AL E R ++++L E + + RE+ +R Q ++ +Q+ Sbjct: 48 PQYRALMGENQDLRKREGQYQDKIEELEKERKEKQERPER-REKFERQHQDKHYQEQQ-- 104 Query: 96 SALETERSNLRRDQQQAASERQQTEGLLADLQRRLEG 132 + E+ L ++Q+ A E+Q ++ L R LE Sbjct: 105 KKHQQEQQQLEAEKQKLAKEKQISDASRQGLNRDLEA 141
>SHIGARICIN#Ribosome inactivating protein family signature. Length = 289 Score = 29.4 bits (66), Expect = 0.014 Identities = 12/47 (25%), Positives = 20/47 (42%), Gaps = 4/47 (8%) Query: 185 NLRRDLDLGTLVPTLPVRAVALASWRLEDQWVTAVRLTNSSGGWITL 231 NLR+ L + +P+ L S Q + LTN + I++ Sbjct: 43 NLRKALPYERKLYDIPL----LRSTLPGSQRYALIHLTNYADETISV 85
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 33.3 bits (76), Expect = 0.001 Identities = 15/46 (32%), Positives = 20/46 (43%), Gaps = 12/46 (26%) Query: 165 SQSELARRLAADGFPVQQSHISRMAD---AVR---------YLLPA 198 +Q EL L DG+ V Q+ +SR V+ Y LPA Sbjct: 21 TQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSYKYSLPA 66
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.5 bits (66), Expect = 0.024 Identities = 18/87 (20%), Positives = 33/87 (37%), Gaps = 5/87 (5%) Query: 33 VLMQP--MQDELGLSKPAIVGAYSV--ALLISGLLSTAAGSIIDRIGGRLLMGSGALLAA 88 V M P M+D LS A +G+ + + + G ++DR G ++ G + Sbjct: 276 VSMVPYMMKDVHQLS-TAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS 334 Query: 89 VMLACLSRVHNATELYLVWAGIGVAMS 115 V S + T ++ + V Sbjct: 335 VSFLTASFLLETTSWFMTIIIVFVLGG 361
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.4 bits (227), Expect = 1e-23 Identities = 33/126 (26%), Positives = 63/126 (50%), Gaps = 1/126 (0%) Query: 2 RILLVEDERDMASWLMRALAQSGFVPDHAADARTAEAFMAGTEYDAIVMDLRLPDKHGLV 61 IL+ +D+ + + L +AL+++G+ ++A T ++A + D +V D+ +PD++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLREMRNRDDRTPVLLLTAQGALQDRVRGLNLGADDFLTKPFALEE-LEARLTALVRRSR 120 +L ++ PVL+++AQ ++ GA D+L KPF L E + AL R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 GRQHPR 126 Sbjct: 125 RPSKLE 130
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 72.4 bits (177), Expect = 8e-16 Identities = 30/182 (16%), Positives = 61/182 (33%), Gaps = 4/182 (2%) Query: 63 SPVSPPPQPQPEPSKPQPKPQPEPEPEKQPEPPPPPPKPEPQAQPKADEVDPEIALQEAK 122 + ++ P Q + + ++ P PPP P P + A+ E E Sbjct: 995 TNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN 1054 Query: 123 KKKEKEEQARQAAEAAKEKARLEEERKQAELKEKKRLEQERQAAEKAAADKAAAEKAAAD 182 ++ E A+ A + K+ ++ + E+ + +E Q E K A + Sbjct: 1055 EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTET----KETATVEKEE 1110 Query: 183 KAAAEKKAKEDAAKKAAAEKAAAEKAAAEKAAADKAAAEKAAAEKKAKEEAAKKAAADKA 242 KA E + ++ K + E++ + A+ A K + A + Sbjct: 1111 KAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQ 1170 Query: 243 LK 244 Sbjct: 1171 PA 1172 Score = 54.7 bits (131), Expect = 3e-10 Identities = 28/195 (14%), Positives = 57/195 (29%), Gaps = 5/195 (2%) Query: 62 NSPVSPPPQPQPEPSKPQPKPQPEPEPEKQPEPPPPPPKPEPQAQPKADEVDPEI--ALQ 119 +PV PP P + + E + + + Q + A E + Q Sbjct: 1022 EAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQ 1081 Query: 120 EAKKKKEKEEQARQAAEAAKEKARLEEERKQAELKEKKRLEQERQAAEKAAADKAAAEKA 179 + + E KE A +E+E K EK + + + +++ + Sbjct: 1082 TNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQP 1141 Query: 180 AADKAAAEKKAKEDAAKKAAAE--KAAAEKAAAEKAAADKAAAEKAAAEKKAKEEAAKKA 237 A+ A E + + + A E+ A E ++ + ++ Sbjct: 1142 QAE-PARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPE 1200 Query: 238 AADKALKDAFRNDAL 252 A N Sbjct: 1201 NTTPATTQPTVNSES 1215 Score = 53.5 bits (128), Expect = 7e-10 Identities = 26/149 (17%), Positives = 48/149 (32%), Gaps = 9/149 (6%) Query: 103 PQAQPKADEVDPE-IALQEAKKKKEKEEQARQAAEAAKEKARLE-----EERKQAELK-- 154 P+ + + VD I + + A ++A + + E Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAE 1042 Query: 155 EKKRLEQERQAAEKAAADKAAAEKAAADKAAAEKKAKEDAAKKAAAEKAAAEKAAAE-KA 213 K+ + + E+ A + A + A +A + KA + A + E E K Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE 1102 Query: 214 AADKAAAEKAAAEKKAKEEAAKKAAADKA 242 A EKA E + +E K + Sbjct: 1103 TATVEKEEKAKVETEKTQEVPKVTSQVSP 1131 Score = 43.5 bits (102), Expect = 1e-06 Identities = 25/190 (13%), Positives = 53/190 (27%), Gaps = 23/190 (12%) Query: 67 PPPQPQPEPSKPQPKPQPEPEP-----EKQPEPPPPPPKPEPQAQPKADEVDPEIALQEA 121 P Q Q E +PQ +P E +P E Q + +P + ++ P Sbjct: 1130 SPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTV 1189 Query: 122 KKKKEKEEQARQAAEAAKEKARLEEERKQAELKEKKRLEQERQAAEKAAADKAAAEKAAA 181 E A + E + + + ++ + E A Sbjct: 1190 NTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATT---------- 1239 Query: 182 DKAAAEKKAKEDAAKKAAAEKAAAEKAAAEKAAADKAAAEKAAAEKKAKEEAAKKAAADK 241 + D + A + + A A KA K + ++ ++ Sbjct: 1240 --------SSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNE 1291 Query: 242 ALKDAFRNDA 251 + + ++ Sbjct: 1292 GQYNVWVSNT 1301 Score = 35.0 bits (80), Expect = 5e-04 Identities = 17/155 (10%), Positives = 42/155 (27%) Query: 65 VSPPPQPQPEPSKPQPKPQPEPEPEKQPEPPPPPPKPEPQAQPKADEVDPEIALQEAKKK 124 V P +P E +P+ + + P + + E + Sbjct: 1139 VQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVEN 1198 Query: 125 KEKEEQARQAAEAAKEKARLEEERKQAELKEKKRLEQERQAAEKAAADKAAAEKAAADKA 184 E A E + + R + ++ + + + A + + + Sbjct: 1199 PENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTN 1258 Query: 185 AAEKKAKEDAAKKAAAEKAAAEKAAAEKAAADKAA 219 A A+ A A A + ++ ++ Sbjct: 1259 AVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQ 1293 Score = 33.5 bits (76), Expect = 0.002 Identities = 22/182 (12%), Positives = 51/182 (28%), Gaps = 11/182 (6%) Query: 74 EPSKPQPKPQPEPEP-EKQPEPPPPPPKPEPQAQPKADEVDPEIALQEAKKKKEKEEQAR 132 E ++ PK + P ++Q E P +P E DP + ++E + + Sbjct: 1117 EKTQEVPKVTSQVSPKQEQSETVQPQAEPAR-------ENDPTVNIKEPQSQTNTTADTE 1169 Query: 133 QAAEAAKEKARLEEERKQAELKEKKRLEQERQAAEKAAADKAAAEKAAADKAAAEKKAKE 192 Q A+ +E +E + K + + Sbjct: 1170 QPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRS 1229 Query: 193 DAAKKAAAEKAAAEKAAAEKAAADKAAAEKAAAEKKAKEE---AAKKAAADKALKDAFRN 249 A ++ +++ ++ +AK + A + + N Sbjct: 1230 VPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMN 1289 Query: 250 DA 251 + Sbjct: 1290 NE 1291
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 91.5 bits (227), Expect = 9e-25 Identities = 24/113 (21%), Positives = 47/113 (41%), Gaps = 11/113 (9%) Query: 61 SVYFDFDSYTVSDQYRGLVETHARYLASH--QQQKIKIEGNTDERGGAEYNLALGQRRAD 118 V F+F+ T+ + + ++ L++ + + + G TD G YN L +RRA Sbjct: 220 DVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQ 279 Query: 119 AVRRMMTLLGVSDNQIETISFGKEKPKATGSSE---------ADFAENRRADI 162 +V + G+ ++I G+ P + + A +RR +I Sbjct: 280 SVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEI 332
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.019 Identities = 11/22 (50%), Positives = 12/22 (54%) Query: 37 VTALLGPNGSGKSTLLKALAGL 58 L G G GKSTL+ L GL Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL 619
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 638 bits (1647), Expect = 0.0 Identities = 177/681 (25%), Positives = 294/681 (43%), Gaps = 75/681 (11%) Query: 11 RNIGISAHIDAGKTTTTERILFYTGITHKIGEVHNGAAVMDWMEQEQERGITITSAATTA 70 NIG+ AH+DAGKTT TE +L+ +G ++G V G D E++RGITI + T+ Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSF 63 Query: 71 FWKGMAGNYPEHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYDAVGGVQPQSETVWRQA 130 W+ ++NIIDTPGH+DF EV RS+ VLDGA+++ A GVQ Q+ ++ Sbjct: 64 QWEN-------TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 131 NKYRVPRLAFVNKMDRVGADFLRVQRQISERLKGDAVPVQLPVGAEDGFEGVIDLVKMKA 190 K +P + F+NK+D+ G D V + I E+L + V Q V M Sbjct: 117 RKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ----------KVELYPNMCV 166 Query: 191 IIWDDASQGVRFEYRDIPAALQAQAQEWHDKMVEKAAEANEALLEKYLGGEALTEAEIKQ 250 + ++ Q + E N+ LLEKY+ G++L E++Q Sbjct: 167 TNFTESEQ------------------------WDTVIEGNDDLLEKYMSGKSLEALELEQ 202 Query: 251 GLRQRTVANEIVPMLCGSAFKNKGVQAMLDAVIDYLPSPVDVPAIKGHDERDHEIERHPT 310 R + P+ GSA N G+ +++ + + S Sbjct: 203 EESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH------------------R 244 Query: 311 DKEPFSALAFKIMTDPFVGQLVFFRVYSGVVKSGDSVYNPVKEKKERLGRILQMHANERR 370 + FKI +L + R+YSGV+ DSV KEK ++ + E Sbjct: 245 GQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-KITEMYTSINGELC 303 Query: 371 EITEVYAGDIAAAVG----VKDVTTGDTLTDPAHVIVLERMVFPEPVISQAVEPKTKADQ 426 +I + Y+G+I + V GDT P ER+ P P++ VEP + Sbjct: 304 KIDKAYSGEIVILQNEFLKLNSVL-GDTKLLPQR----ERIENPLPLLQTTVEPSKPQQR 358 Query: 427 EKMGIALGRLAQEDPSFRVRTDEESGQTIISGMGELHLEILVDRMKREFGVEATVGKPQV 486 E + AL ++ DP R D + + I+S +G++ +E+ ++ ++ VE + +P V Sbjct: 359 EMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTV 418 Query: 487 AYRETIRKTCDEVEGKFVKQSGGRGQYGHVVLKLEPQEPGKGYEFVDAIKGGVVPREFIP 546 Y E K E + + + L + P G G ++ ++ G + + F Sbjct: 419 IYMERPLKK---AEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQN 475 Query: 547 AVDKGIREALNAGVLAGYPVVDVKATLFFGSYHDVDSNENAFKMAGSMAFKEGMRRADPV 606 AV +GIR G L G+ V D K +G Y+ S F+M + ++ +++A Sbjct: 476 AVMEGIRYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTE 534 Query: 607 LLEPMMQVEVETPEDFTGNVMGDLSSRRGMVQGMEDIAGGGGKVVRAEVPLAEMFGYSTS 666 LLEP + ++ P+++ D + + ++ E+P + Y + Sbjct: 535 LLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ--LKNNEVILSGEIPARCIQEYRSD 592 Query: 667 LRSLTQGRATYTMEFKHYAEA 687 L T GR+ E K Y Sbjct: 593 LTFFTNGRSVCLTELKGYHVT 613
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 346 bits (889), Expect = e-120 Identities = 151/344 (43%), Positives = 219/344 (63%) Query: 5 MSGEKTEQPTQKKLRDARQKGDVAHSKDFTQTLLVLALFGYLLGNAHGIVEALGRLVLIP 64 MSGEKTEQPT KK+RDAR+KG VA SK+ T L++AL L+G + E +L+LIP Sbjct: 1 MSGEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIP 60 Query: 65 STLVGQSFEQALPIALDAALREAVYLVLPFVLIVLVVGMFSEFLQVGVVLAFEKLKPSAK 124 + F QAL +D L E YL P + + ++ + S +Q G +++ E +KP K Sbjct: 61 AEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIK 120 Query: 125 KLNVMSNLKNIFSKKNLVELLKSIIKIAFLSVLVTLVVRDALPELMAVPHSGLAGLEAGV 184 K+N + K IFS K+LVE LKSI+K+ LS+L+ ++++ L L+ +P G+ + + Sbjct: 121 KINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLL 180 Query: 185 GGMMRALIVNIAVAYVVISLADFVWQRMQYRKGLMMSKEDIKQEFKEMEGDPHIKHKRKH 244 G ++R L+V V +VVIS+AD+ ++ QY K L MSK++IK+E+KEMEG P IK KR+ Sbjct: 181 GQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQ 240 Query: 245 LHQEMVMHGAVASTRKASVLVTNPTHLAVAIYYEPDETPLPVVLAKGEGALAEQMMRAAR 304 HQE+ + +++SV+V NPTH+A+ I Y+ ETPLP+V K A + + + A Sbjct: 241 FHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAE 300 Query: 305 EAGVPVMQNIPLARALMASALPDQYIPSELIEPVAEVLRLVRKL 348 E GVP++Q IPLARAL AL D YIP+E IE AEVLR + + Sbjct: 301 EEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQ 344
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 143 bits (363), Expect = 5e-44 Identities = 46/230 (20%), Positives = 96/230 (41%), Gaps = 4/230 (1%) Query: 14 LSTLALTQPRILALCAMLPLFNRQLLPGMLRYALCAAIGLVLVPALAPRYAVIDLDAVEL 73 L+ R+LAL + P+ + + +P ++ L I + P+L + Sbjct: 13 LNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPANDVPVFSFF--A 70 Query: 74 VLLVAKEVFIGLVMGFLVAIPFWIFEAVGFVVDNQRGASLGATINPATGNDSSPLGILFN 133 + L +++ IG+ +GF + F G ++ Q G S ++PA+ + L + + Sbjct: 71 LWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIMD 130 Query: 134 QAFMVFFLVGGGFMLMLTMLYDSFRLWDLWDWAPTLRRESVPLMLDQLGRFLRLTLLFAA 193 ++ FL G + ++++L D+F + L + + L+ A Sbjct: 131 MLALLLFLTFNGHLWLISLLVDTFHTLPI--GGEPLNSNAFLALTKAGSLIFLNGLMLAL 188 Query: 194 PAIISMFLAEVGLALVSRFAPQLQVFFLAMPIKSALALLVMVLYMSTLFE 243 P I + + L L++R APQL +F + P+ + + +M M + Sbjct: 189 PLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAP 238
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 71.3 bits (175), Expect = 3e-20 Identities = 36/79 (45%), Positives = 46/79 (58%) Query: 5 DLVSYMTQALYLVLWLSLPPIAVAAIVGTLFSLFQALTQIQEQTLSFAVKLIAVFATIML 64 DLV +ALYLVL LS P VA I+G L LFQ +TQ+QEQTL F +KL+ V + L Sbjct: 3 DLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFL 62 Query: 65 TARWLSAELYNFTISVFDL 83 + W L ++ V L Sbjct: 63 LSGWYGEVLLSYGRQVIFL 81
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 230 bits (587), Expect = 9e-79 Identities = 87/224 (38%), Positives = 132/224 (58%), Gaps = 14/224 (6%) Query: 5 DPISLAVVLALLALVPLAAVMTTSFLKIAVVLTLVRNALGVQQVPPNMALYGLALILSAY 64 + ISL +LA L+P T F+K ++V +VRNALG+QQ+P NM L G+AL+LS + Sbjct: 3 NDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLSMF 62 Query: 65 VMGPVVMQIGDELRAPPAVAAPGTPEPDRLEGILEAVARGAEPMRAFMLKNSRAEQRDFF 124 VM P++ + + + + V G + R +++K S E FF Sbjct: 63 VMWPIMHDAYVYFEDED-------VTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFF 115 Query: 125 LRTARGLWGEQQARN-------LKEDDLLVLIPSFLLSELTAAFQIGFLLYLPFVIIDLI 177 ++ +++ + L+P++ LSE+ +AF+IGF LYLPFV++DL+ Sbjct: 116 ENAQLKRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLV 175 Query: 178 VSNILLAMGMMMVSPVTISMPLKLFLFVMVDGWTRLIQGLVLSY 221 VS++LLA+GMMM+SPVTIS P+KL LFV +DGWT L +GL+L Y Sbjct: 176 VSSVLLALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQY 219
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 73.5 bits (180), Expect = 8e-17 Identities = 37/166 (22%), Positives = 70/166 (42%), Gaps = 10/166 (6%) Query: 187 PAANEIDADAVPVRIAACLGWTELDAAQLRSLAPRDTVFLDHCLVSPEGELWLGAGAQGL 246 PA + + +G ++ + L + D + + E++ A G Sbjct: 138 PAVGGGRPKMLRWPLRFVIGSSDTQRSLLGRIGIGDVLLIRTS----RAEVYCYAKKLGH 193 Query: 247 RVRRQDSSYLVTQGWTSLMTETPQSPQDADAGAQTPLDIDAIPVRLTFELGERLITLGEL 306 R + +V + E + + A+ ++ +PV+L F L + +TL EL Sbjct: 194 F-NRVEGGIIVETLDIQHIEEENNTTETAET----LPGLNQLPVKLEFVLYRKNVTLAEL 248 Query: 307 RQLQPGETFDLARPLAEGPVLVRANGALVGSGELVEIDGRIGVTLH 352 + + L AE V + ANG L+G+GELV+++ +GV +H Sbjct: 249 EAMGQQQLLSLPTN-AELNVEIMANGVLLGNGELVQMNDTLGVEIH 293
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 97.7 bits (243), Expect = 4e-25 Identities = 42/174 (24%), Positives = 73/174 (41%), Gaps = 4/174 (2%) Query: 32 ALLLAACGARVELFSAANESEANEVLSVLLDAGIAAQKATTKTGVAVSVDGQQVARALDI 91 +L A LFS ++ + +++ L I + A+ V +V Sbjct: 41 MVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIPYR--FANGSGAIEVPADKVHELRLR 98 Query: 92 LRSRGLPRERFDGMGQIFRKEGLVSSPLEERARYIYALSQELTNTLSQMDGVLAARVHVV 151 L +GLP+ G ++ +E S E+ Y AL EL T+ + V +ARVH+ Sbjct: 99 LAQQGLPKGGAVGF-ELLDQEKFGISQFSEQVNYQRALEGELARTIETLGPVKSARVHLA 157 Query: 152 LPERGGVGENTTPSTAAVFIKHQTGYNLDALQPQ-IRKLVTHAIPGLTEDRVSI 204 +P+ +A+V + + G LD Q + LV+ A+ GL V++ Sbjct: 158 MPKPSLFVREQKSPSASVTVTLEPGRALDEGQISAVVHLVSSAVAGLPPGNVTL 211
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 56.5 bits (136), Expect = 8e-13 Identities = 29/137 (21%), Positives = 58/137 (42%), Gaps = 4/137 (2%) Query: 13 EALYRGLEALPSNDRLTPEQLEVVYALAYAHVAQEQYAQALPVFAFLAQYGPTRKHYLIG 72 E+ +G + + ++ + LE +Y+LA+ +Y A VF L + +G Sbjct: 16 ESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLG 75 Query: 73 LGLCLQMLGRLEEAINIFSLVLTLYPDSLSTALRIAECQLAARQFDQARR----TLQLLS 128 LG C Q +G+ + AI+ +S + AEC L + +A +L++ Sbjct: 76 LGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIA 135 Query: 129 AADVPSQVRARAEALLQ 145 ++ R ++L+ Sbjct: 136 DKTEFKELSTRVSSMLE 152
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 68.1 bits (166), Expect = 1e-15 Identities = 52/205 (25%), Positives = 82/205 (40%), Gaps = 26/205 (12%) Query: 28 RTAVVVIDMQQYFTLPGYQGECAAARDIIAPVNRLCDAVRAAGGTVVWV-QTASDNADA- 85 R +++ DMQ YF + + ++ A + +L + G VV+ Q S N D Sbjct: 30 RAVLLIHDMQNYFVDA-FTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDDR 88 Query: 86 -----FWSHHHGVMLTPERSARRLETLRRDSPGFALHPDLRPADSDLRVTKRFYSAMATG 140 FW L + +L P D DL +TK YSA Sbjct: 89 ALLTDFWG----------------PGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFK-- 130 Query: 141 SSELEPLLRGRGVDTLLIAGTVTNVCCESTARDAMMRDFRTIMVDDALAAVTPAEHENAL 200 + L ++R G D L+I G ++ C TA +A M D + V DA+A + +H+ AL Sbjct: 131 RTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSLEKHQMAL 190 Query: 201 HGWLLFFGDVLSVDEVSTRLRPAQA 225 + D + +L+ A A Sbjct: 191 EYAAGRCAFTVMTDSLLDQLQNAPA 215
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 68.8 bits (168), Expect = 9e-15 Identities = 60/371 (16%), Positives = 127/371 (34%), Gaps = 44/371 (11%) Query: 32 LPQLAAEFGATTGQAARAVTAFAVAYGVLQMFFGPVGDRYGKYRVVSVATFACALGSAGA 91 LP +A +F TAF + + + +G + D+ G R++ GS Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 92 FVAES-LDVLVFCRALSGAAGAGIVPLSMAWIGDTVPYERRQATLARFLTGTILGMAAGQ 150 FV S +L+ R + GA A L M + +P E R + +G G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 151 LAGGLFADTLGWRWAFAALVVGYLVVGTLLQLEVRRQRALGLGVVDPNAPRQGFVAQARL 210 GG+ A + W + ++ ++ +++ ++ G D V Sbjct: 157 AIGGMIAHYIHWSYLLLIPMI--TIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFF 214 Query: 211 VLGTP---WARVVLATVF------------------------------IEGLLVFGALA- 236 +L T + ++++ + + G ++FG +A Sbjct: 215 MLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAG 274 Query: 237 ---FAPSYLHERFDISLTAAGALVAVYA-VGGLLYTVVAGRVLKRLGERGLAVAGGLVLG 292 P + + +S G+++ + +++ + G ++ R G + G L Sbjct: 275 FVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS 334 Query: 293 VAFLSYLLGPVW-LWSLLASVLAGFGYYLLHATLQTNATQMV--PSARGTAVAWFASCLF 349 V+FL+ W + ++ G T+ + G ++ F Sbjct: 335 VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSF 394 Query: 350 MGQAAGVALAG 360 + + G+A+ G Sbjct: 395 LSEGTGIAIVG 405
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 28.3 bits (63), Expect = 0.029 Identities = 13/70 (18%), Positives = 26/70 (37%), Gaps = 15/70 (21%) Query: 118 VVVGHSMGA--LPA----LLAASQRRVAGVVLMAPSPPANLP---------GALGLPPVP 162 +++G+S GA +P + A ++ V G VL++PS ++ + Sbjct: 120 ILIGYSFGAEVIPFVLNEMPARYRKNVLGAVLLSPSQSSDFEIHVSEMVTSDNQSARYLT 179 Query: 163 ADAVRATPAA 172 V Sbjct: 180 LPEVNKQTTV 189
>PHAGEIV#Gene IV protein signature. Length = 426 Score = 31.4 bits (71), Expect = 0.004 Identities = 14/50 (28%), Positives = 22/50 (44%), Gaps = 2/50 (4%) Query: 54 RTFAQFLGKQTGQTVIVEDRPGAGGIVGTNAARNAAADGYTFLLSTNSTH 103 R F + KQTG++VIV P G V ++ + F +S + Sbjct: 32 RDFVTWYSKQTGESVIVS--PDVKGTVTVYSSDVKPENLRDFFISVLRAN 79
>PF07132#Harpin protein (HrpN) Length = 356 Score = 28.5 bits (63), Expect = 0.014 Identities = 26/87 (29%), Positives = 37/87 (42%) Query: 31 GGCANRSASSGVYSYDQAQREQIVRTGTVTGVRPIVIQNDKSSGVGMLAGGALGGVAGNA 90 GG ++SA G S Q I+ T G G+G GG GG+ G Sbjct: 32 GGSPSQSAFGGQRSNIAEQLSDIMTTMMFMGSMMGGGLGGGLGGLGSSLGGLGGGLLGGG 91 Query: 91 IGGGTGRTIATVGGAILGALAGNAVEN 117 +GGG G ++ + G+ LG G A+ Sbjct: 92 LGGGLGSSLGSGLGSALGGGLGGALGA 118
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 36.1 bits (83), Expect = 2e-04 Identities = 22/114 (19%), Positives = 33/114 (28%), Gaps = 5/114 (4%) Query: 51 MPAAAIPASNTPIAPPA---PAAPQAIAAPVL--VTPPAPPVDDGAPPPVRRPSVEPREV 105 +PA A P S T +AP P A Q PV+ P P + PV +P+ Sbjct: 43 LPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPK 102 Query: 106 APWDDLPDEPASPGIRPGASGASPAAAPSVAPTEEPAPRPLASAVPPAVLRGRD 159 + + + AP + A+ P Sbjct: 103 PKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASG 156 Score = 28.4 bits (63), Expect = 0.048 Identities = 20/97 (20%), Positives = 24/97 (24%), Gaps = 1/97 (1%) Query: 63 IAPPAPAAPQAIAAPVLVTPPAPPVDDGAPPPVRRPSVEPREVAPWDDLPDEPASPGIRP 122 I PAPA P ++ P P PV P EP E P +P Sbjct: 41 IELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEP-EPIPEPPKEAPVVIEKPKP 99 Query: 123 GASGASPAAAPSVAPTEEPAPRPLASAVPPAVLRGRD 159 P + P A P Sbjct: 100 KPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPAR 136
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 52.7 bits (126), Expect = 1e-10 Identities = 23/130 (17%), Positives = 42/130 (32%), Gaps = 5/130 (3%) Query: 3 RRENTERQILQALEDQIKETGMGGVGINAIAKRAGVSKELIYRYFDGMPGLMLAWMQEQ- 61 + T + IL + G+ + IAK AGV++ IY +F L + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 62 DFWTRNPGLLAADESSQRSPGELVLSMLRAQIDALAGNETLREVRRWELIERNEVSAPLA 121 A P ++ +L +++ E R + E+I Sbjct: 68 SNIGELELEYQAKFP--GDPLSVLREILIHVLESTVTEERRRLLM--EIIFHKCEFVGEM 123 Query: 122 ERRERAARGF 131 ++A R Sbjct: 124 AVVQQAQRNL 133
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 45.5 bits (108), Expect = 4e-07 Identities = 31/128 (24%), Positives = 46/128 (35%), Gaps = 27/128 (21%) Query: 2 PAQPDPQEYDLIISGGLIADGLGGPARRADVAINGERIAAIGD--------------GSG 47 + D +I+ LI D G +AD+ + RIAAIG G G Sbjct: 60 QVTREGGAVDTVITNALILDHWG--IVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPG 117 Query: 48 WRARRRIDASGRVVAPGFIDCHTHDDRALLGSPLMRPKVSQGVTTVVTGNCGISLAPVHA 107 I G++V G +D H H + + + G+T ++ G G P H Sbjct: 118 TEV---IAGEGKIVTAGGMDSHIH----FICPQQIEEALMSGLTCMLGGGTG----PAHG 166 Query: 108 PGDTVPPP 115 T P Sbjct: 167 TLATTCTP 174
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 29.6 bits (66), Expect = 0.026 Identities = 15/44 (34%), Positives = 20/44 (45%), Gaps = 1/44 (2%) Query: 9 GVVGMATAYYLHREGHRVSVVDASPGP-GLATSRANGAQLSYSF 51 V T Y L+ EGH DA GP G + GA+ Y++ Sbjct: 123 NVDEGFTVYRLNWEGHEHHPADAYDGPKGGNYPKPTGARDEYTY 166
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 820 bits (2119), Expect = 0.0 Identities = 283/1032 (27%), Positives = 509/1032 (49%), Gaps = 27/1032 (2%) Query: 7 FIVRPVATTLLSLAVVLAGMLSFFLLPVAPLPQMDIPTISVSASLPGASPETMASSVATP 66 FI RP+ +L++ +++AG L+ LPVA P + P +SVSA+ PGA +T+ +V Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 67 LERSLGSIAGVTEMTSSS-SQGSTRVTLQFDLSRDINGAARDVQAAINAARSLLPTSLRS 125 +E+++ I + M+S+S S GS +TL F D + A VQ + A LLP ++ Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ- 123 Query: 126 NPTYHKSNPSDAPIMTLAMTSDT--LSQGQMYDLASTIVAQKLSQVDGVGEVTVGGSSLP 183 S + +M SD +Q + D ++ V LS+++GVG+V + G+ Sbjct: 124 QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY- 182 Query: 184 AVRVTVLPGALANRGVSLDEVRTALANANANRPKGVLENDQY------HWQIMVNDQLSR 237 A+R+ + L ++ +V L N G L + I+ + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 238 AEQYRPLIV-AWRDGAPVRVSDVARVEDSVEDLFQTGFYNQRNAILMIVRRQADANIIET 296 E++ + + DG+ VR+ DVARVE E+ N + A + ++ AN ++T Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 297 VDAVRAQLPTLLALMPADVQLTVAQDRTPSIRASLHEAELTLIIAVGLVVLVVLLFLRRW 356 A++A+L L P +++ D TP ++ S+HE TL A+ LV LV+ LFL+ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 357 RAAIIPSVAVPVSLIGTFCIMYLCGFTLNTISLMALIVATGFVVDDAIVVLENIMRH-VE 415 RA +IP++AVPV L+GTF I+ G+++NT+++ +++A G +VDDAIVV+EN+ R +E Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 416 NGMSPMRAALRGSREVGFTVLSMSLSLVAVFIPILLMGGVAGRLFREFAVTLSASIMVSL 475 + + P A + ++ ++ +++ L AVFIP+ GG G ++R+F++T+ +++ +S+ Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 476 VVSLTLTPMMCARLLKAEPKEP-KPPGRLARWAERGFDWMQDGYRRSLAWALAHGRLMML 534 +V+L LTP +CA LLK E + G W FD + Y S+ L +L Sbjct: 483 LVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLL 542 Query: 535 VLAAAVGLNVYLYTVVPKGFFPQQDTGQLLGFFRVDQGTSFQATVPKLEALRKVVLADP- 593 + A V V L+ +P F P++D G L ++ G + + T L+ + L + Sbjct: 543 IYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEK 602 Query: 594 ----AVQSMTGYAGGRGGSNSSFMQIQLKPLGER---KVSADQVINRLRARLQNMPGARM 646 +V ++ G++ N+ + LKP ER + SA+ VI+R + L + + Sbjct: 603 ANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFV 662 Query: 647 FLVAQQDIRVGGRQSQGSYDYTLMSG-DLQLLRAWMPKVQQAMAKVP-EITDVDTDVEDK 704 I G + ++ +G L ++ A+ P + V + + Sbjct: 663 IPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLED 722 Query: 705 GREINLVIDRDAATRLGVSMATISTVLNNSFSQRQVSVMYGPLNQYHVVLGVDQRFAQDI 764 + L +D++ A LGVS++ I+ ++ + V+ + + D +F Sbjct: 723 TAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLP 782 Query: 765 ESLKQVEVITSTGARVPMAAFARFENANAPLSVQHQGLFVADTVSFSLAPGVSLGQATAA 824 E + ++ V ++ G VP +AF ++ + + APG S G A A Sbjct: 783 EDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMAL 842 Query: 825 IDAAVARIGLPSDQIQAGFQGTAAVLQQTLAQQPWLILAALVTMYIVLGILYESFVHPLT 884 ++ ++ LP+ I + G + + + Q P L+ + V +++ L LYES+ P++ Sbjct: 843 MENLASK--LPAG-IGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 885 ILSTLPSAGLGALLALLLVRTDFTLIALIGVFLLIGIVKKNAIMMVDFALEAERNQHMAP 944 ++ +P +G LLA L + ++G+ IG+ KNAI++V+FA + + Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 945 REAIFQACLTRFRPIMMTTMAAIFGALPLVLATGAGVEMRQPLGITIVGGLVLSQILTLY 1004 EA A R RPI+MT++A I G LPL ++ GAG + +GI ++GG+V + +L ++ Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1005 TTPVVYLYLDRF 1016 PV ++ + R Sbjct: 1020 FVPVFFVVIRRC 1031
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 40.9 bits (96), Expect = 2e-06 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 6/40 (15%) Query: 1 MKILVIGGTGLIGSKLVKLLIERGHDAVAASPATGVDTIT 40 MK LV G G IG + K L+E GH V G+D + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVV------GIDNLN 34
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 86.0 bits (213), Expect = 1e-20 Identities = 67/215 (31%), Positives = 92/215 (42%), Gaps = 16/215 (7%) Query: 55 LISSYAFAYAIAAPILGHLSDRVDRRRLLLAGLLSFAVDGVGVALAPTLEVAMALRIFGG 114 L++ YA AP+LG LSDR RR +LL L AVD +A AP L V RI G Sbjct: 48 LLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAG 107 Query: 115 LASAVIIPNAFALVADIMPRDRQAEAMGVVMLGMTAGIAMGPALAGLLTDWIGWRAPFLL 174 + A A A +ADI D +A G + G+ GP L GL+ APF Sbjct: 108 ITGAT-GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFA 165 Query: 175 TSAGCLVACVVSGMSIPRRHAAR-------APRQRSAIHWLRARTIVRPLLAKG----LW 223 +A + + +P H A ++ W R T+V L+A L Sbjct: 166 AAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLV 225 Query: 224 NGAGVAAFLLSGEILRARYQLDVAQVGLSATAFGI 258 A +++ GE R+ D +G+S AFGI Sbjct: 226 GQVPAALWVIFGE---DRFHWDATTIGISLAAFGI 257
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 26.6 bits (58), Expect = 0.004 Identities = 9/49 (18%), Positives = 16/49 (32%), Gaps = 1/49 (2%) Query: 4 AYLTKTWGRDFSAILVWILGAIEAYVIYAAVSFVLSAAL-VWAMTALAA 51 T W F + A +YV+ S + L +W + + Sbjct: 454 IKDTGDWKPLFLTLEKKAADAGVSYVVALLFSLLAGTTLGIWGIAIVTG 502
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 50.2 bits (120), Expect = 2e-09 Identities = 20/99 (20%), Positives = 33/99 (33%), Gaps = 2/99 (2%) Query: 147 AAAPRAVGAADVRPRVPRQVLQQGLAGMRYQPGREAQEPFRQAKARVVDGFESDYIRLAL 206 +P AA Q +++ + G RV+ E I AL Sbjct: 388 PDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPS--GLYDRVLAEMEYPLILAAL 445 Query: 207 SRHQGNVARAARASSKHRRAFWALMRKHGIDAGPYRRQA 245 + +GN +AA +R +R+ G+ R A Sbjct: 446 TATRGNQIKAADLLGLNRNTLRKKIRELGVSVYRSSRSA 484
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 47.2 bits (112), Expect = 1e-07 Identities = 34/163 (20%), Positives = 67/163 (41%), Gaps = 6/163 (3%) Query: 42 IIW--IANLFANLGTWAQSVAAAWVITTEQSSPLMVAMIQVAAAFPLVALSILTGVLADN 99 +IW I + F+ L +V+ + P + A + + G L+D Sbjct: 16 LIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 100 YDRRKVMLVGMLLELAGGIFITILAYIGLLHPITLIISVFCIAIGSAIVTPAWQAAVGEQ 159 ++++L G+++ G +++ ++G LI++ F G+A V Sbjct: 76 LGIKRLLLFGIIINCFG----SVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARY 131 Query: 160 VPREHIGSAVLLNSVNYNVARAVGPAIGGLLLGAAGAPTVFLL 202 +P+E+ G A L + VGPAIGG++ + L+ Sbjct: 132 IPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLI 174 Score = 29.8 bits (67), Expect = 0.032 Identities = 23/102 (22%), Positives = 36/102 (35%), Gaps = 3/102 (2%) Query: 90 SILTGVLADNYDRRKVMLVGMLLELAGGIFITILAYIGLLHPITLIISVFCIAIGSAIVT 149 + G+L D V+ +G+ F+T + II VF + S T Sbjct: 310 GYIGGILVDRRGPLYVLNIGVTFLSVS--FLTASFLLETTSWFMTIIIVFVLGGLSFTKT 367 Query: 150 PAWQAAVGEQVPREHIGSAVLLNSVNYNVARAVGPAIGGLLL 191 +E LLN ++ ++ G AI G LL Sbjct: 368 VISTIVSSSLKQQEAGAGMSLLNFTSF-LSEGTGIAIVGGLL 408
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 28.9 bits (64), Expect = 0.037 Identities = 37/161 (22%), Positives = 63/161 (39%), Gaps = 6/161 (3%) Query: 161 NGTPAGTAEGADATGAGASTPTTAASRALAAYAAASDTALDSDADTADTPAADTAAQGAA 220 NGTP G+ G G+ + ++AA A A ++ A + A+ A A AQ A Sbjct: 26 NGTPDGSGSGGGGGKGGSKSESSAAIHATAKWSTAQ--LKKTQAEQAARAKAAAEAQAKA 83 Query: 221 AAARADAAKAASASVDTDTAGDRNDKAGAPTESRHEPQAAQRRQDDAQAVRDAIRAMKEL 280 A R DA + + + + TE H AA + +D+ + A ++ Sbjct: 84 KANR-DALTQRLKDIVNEALRHNASRTPSATELAHANNAAMQAEDERLRLAKAEEKARKE 142 Query: 281 LAMLKSKLR---QHDKEAQKQVAEVRDALAEAEKTAQAIDG 318 + + Q KE +++ AE L AE + + Sbjct: 143 AEAAEKAFQEAEQRRKEIEREKAETERQLKLAEAEEKRLAA 183
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 28.4 bits (63), Expect = 0.042 Identities = 13/27 (48%), Positives = 18/27 (66%) Query: 228 SGTAAAIVLLAGAATAAAGPLAFIGLA 254 S +AAA L+A A T A PL+F+ +A Sbjct: 301 STSAAAAGLIASAVTLAISPLSFLSIA 327
>RTXTOXINC#Gram-negative bacterial RTX toxin-activating protein C signature. Length = 170 Score = 29.1 bits (65), Expect = 0.042 Identities = 16/52 (30%), Positives = 22/52 (42%), Gaps = 3/52 (5%) Query: 264 YIKNTTFLGEPDWNTYDRNIWTAGWQLEHQFNDAWKVSQNARYTHVDSLYRA 315 Y+ + T L DW + DR W W F D + + R D L+RA Sbjct: 70 YLNDVTSLVAEDWTSGDR-KWFIDWIAP--FGDNGALYKYMRKKFPDELFRA 118
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.1 bits (73), Expect = 0.004 Identities = 17/119 (14%), Positives = 39/119 (32%), Gaps = 10/119 (8%) Query: 310 LRRSAERYLALSHTDPDAMAFCRECALVSNAEQLEHLLRR----------DGRVLRLVGR 359 ++++ + L + D +A+ + N +LE+L+RR ++ R Sbjct: 325 VQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELR 384 Query: 360 QVKPGSAFRRGMQNADTPDPSAALDPDDAGQADGVIAWPAGLSFRVRSLYALNRDLLEE 418 P S + + + S A++ + R L + L+ Sbjct: 385 SEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILA 443
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 40.6 bits (95), Expect = 1e-07 Identities = 15/54 (27%), Positives = 26/54 (48%), Gaps = 5/54 (9%) Query: 26 VEVGATIKPGDVVGIVEVMKQFNQIEAEVGGVVAEILVADGDPVEPGQALLRIE 79 VE+ AT G + + +I+ +V EI+V +G+ V G LL++ Sbjct: 80 VEIVAT-----ANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLT 128
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 33.8 bits (77), Expect = 4e-04 Identities = 43/212 (20%), Positives = 73/212 (34%), Gaps = 23/212 (10%) Query: 1 MYRRTRALALASACGATLMLAAPAQAHEAGDILFRVGATQVRPSSNNGSVLDGSVKLDVN 60 M + A+A+A A AT+ AAP D + GA ++ ++ + Sbjct: 1 MKKTAIAIAVALAGFATVAQAAPK------DNTWYTGAKLGWSQYHDTGFINNNGP-THE 53 Query: 61 NNVRPSFTLAYMATRNIGIELLGAWPFEHDVRGSGLGKIGSSKQLPPTLSLQWHILPDSM 120 N + Y +G E+ W +GS ++ + T L + I D Sbjct: 54 NQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLD 113 Query: 121 VQPYIGVGINYTKFFDTKAEGALKGSDLKLGDSWGVAAQLGADIKISERWFMNADIRYID 180 + +G + DTK+ K D + V A G + I+ + ++ + Sbjct: 114 IYTRLGGMVWRA---DTKSNVYGKNHDTGVS---PVFA-GGVEYAITPEIATRLEYQWTN 166 Query: 181 IKSKVKLNGEHIGTARINPWVA--TLGVGYRF 210 N T P +LGV YRF Sbjct: 167 -------NIGDAHTIGTRPDNGMLSLGVSYRF 191
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 33.3 bits (76), Expect = 0.002 Identities = 34/157 (21%), Positives = 57/157 (36%), Gaps = 5/157 (3%) Query: 226 GAGYIIPATFLPAMAREIIPDPAVFGWAWPLFGLAAALSCLLAPRVAQARDD---KTVWR 282 G G I+P LP + R+++ V L L A + AP + D + V Sbjct: 20 GIGLIMPV--LPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLL 77 Query: 283 GAQALMALGMLAVALWHDIAAVIVAALLVGGTFMVITQSGMLVAQRLAGSAAPRAAAVMT 342 + A A+ +A + + + ++ G T +G +A G R M+ Sbjct: 78 VSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMS 137 Query: 343 SAFAAGQIVGPLLASGAARWGATLPQVLAAGAALLAL 379 + F G + GP+L + P AA L Sbjct: 138 ACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNF 174
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 70.0 bits (171), Expect = 2e-15 Identities = 35/166 (21%), Positives = 62/166 (37%), Gaps = 32/166 (19%) Query: 107 ASTSLGSGVVVNHDGYVLTNYHVVQAADAIEVALA------------DGRKDTAKVVGAD 154 T + SGVVV +LTN HVV A AL +G ++ Sbjct: 99 TGTFIASGVVVG-KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYS 157 Query: 155 PDTDLAVLKLATLR-------NLPAATLAPDRGLRVGDVVLAIGNPFG---VGQTTTQGI 204 + DLA++K + + AT++ + +V + G P ++G Sbjct: 158 GEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGK 217 Query: 205 VSALGRNGLGLNTYENFIQTDAAINPGNSGGALVDAQGNLVGINTA 250 ++ L + Q D + GNSG + + + ++GI+ Sbjct: 218 ITYLKGEAM---------QYDLSTTGGNSGSPVFNEKNEVIGIHWG 254
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 125 bits (316), Expect = 5e-40 Identities = 66/146 (45%), Positives = 86/146 (58%), Gaps = 15/146 (10%) Query: 6 GFVKEFRDFAVKGNAVDLAVGVIIGAAFGKIVDSLVKDIVMPLVNFVLGGSVDFSNKFLV 65 +KEFR+FA++GN VDLAVGVIIGAAFGKIV SLV DI+MP + ++GG +DF + Sbjct: 2 SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGG-IDFKQFAVT 60 Query: 66 LSMPAGYNGPMTYADLTKAGANVFAWGNFVTIIINFVLLAFVIFWMVKAIYKARTKAEEA 125 L G A V +G F+ + +F+++AF IF +K I K K EE Sbjct: 61 LRDAQG-----------DIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEP 109 Query: 126 PAPAAPAATPEDVALLREIRDLLKKQ 151 A AP + LL EIRDLLK+Q Sbjct: 110 AAAPAPTK---EEVLLTEIRDLLKEQ 132
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 38.7 bits (90), Expect = 3e-05 Identities = 64/339 (18%), Positives = 124/339 (36%), Gaps = 19/339 (5%) Query: 67 VVGHVADRYDRRKIVAICMAVETLATLLLAIAALHGVGGKTLIYATLIIMSSARAFEAPT 126 V+G ++DR+ RR ++ + +A + ++A A V +Y I+ A Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWV-----LYIGRIVAGITGA-TGAV 115 Query: 127 LTTLIPAIVPREWLPRATALSSSGGQIAQIAGPALGGIGYGLGAGWVYCVAAALYLCGFA 186 I I + R S+ +AGP LGG+ G + AAAL F Sbjct: 116 AGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFL 175 Query: 187 CIASMSIDRAPPRREPTTWRT--LFAGITFIFQRRILLGTLSLDLFAVLLGGA-TALLPI 243 + + R P A + ++ +++ L+G AL I Sbjct: 176 TGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVI 235 Query: 244 FAKDILNAGPWALG-ALRAAPACGAMLMSLTLARLS--LGEHVGRLLFGALILFGLATTV 300 F +D + +G +L A ++ ++ ++ LGE R L +I G + Sbjct: 236 FGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGER--RALMLGMIADGTGYIL 293 Query: 301 FGLSTSIPLSVGALVVLGAADAISVVVRSSLVQLNTPDHMLGRVSAVNTLFVGASNQLGE 360 +T ++ +V+L + + +++ + G++ ++ +G Sbjct: 294 LAFATRGWMAFPIMVLLASGGIGMPAL-QAMLSRQVDEERQGQLQGSLAALTSLTSIVGP 352 Query: 361 FESGVMAALLGAVPAVVVGGLGTIAVAGLWMHWFPELRR 399 ++ + A G IA A L++ P LRR Sbjct: 353 ----LLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 121 bits (305), Expect = 1e-35 Identities = 71/252 (28%), Positives = 122/252 (48%), Gaps = 10/252 (3%) Query: 5 LKSKTALVTGAYSGLGRHFALRLAEAGARVALCGRRTELGETLATEIRAQGGQACVAGMD 64 ++ K A +TGA G+G A LA GA +A E E + + ++A+ A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 65 VTQPDSVLAAFTQVEQAFGPVDIVVNNAGIAMTRPALDISEDEWTGLIDVNLNGAWRVAQ 124 V ++ ++E+ GP+DI+VN AG+ +S++EW VN G + ++ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 125 CAARHFHGHGRPGAIINIASILGQRVASHVAAYTAAKAGLLHLTRALALEWARHGIRVNA 184 +++ R G+I+ + S + +AAY ++KA + T+ L LE A + IR N Sbjct: 126 SVSKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 185 LAPGYIGTDLNRDFFATPAGEALVKR---------IPQRRLGRPQDLDGPLLLLASDASA 235 ++PG TD+ +A G V + IP ++L +P D+ +L L S + Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244 Query: 236 YMTGAVIDVDGG 247 ++T + VDGG Sbjct: 245 HITMHNLCVDGG 256
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 31.3 bits (70), Expect = 0.008 Identities = 12/45 (26%), Positives = 16/45 (35%) Query: 43 TQGTTPRMPVAPVRAQPPVQTAPSAATPLGGAPPPGMPAQPAAPA 87 T P + + A PP PS+ TP+ P P P Sbjct: 405 TTAEAPPLILTWTPASPPGNQNPSSTTPVVPKPVPVYEGATLTPV 449
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 464 bits (1194), Expect = e-161 Identities = 199/562 (35%), Positives = 311/562 (55%), Gaps = 36/562 (6%) Query: 1 MIFSFSLLLLWNNWQIHNGKPSLFGAPTPTASTNANGTPAAANNATPSVPNAPPATAAAP 60 + F ++W W+ A T +T A +AA Sbjct: 10 IALLFVSFMIWQAWEQDKNPQPQ--AQQTTQTT------------------TTAAGSAAD 49 Query: 61 SAVPGAAAPVPTRSEEVVITTDVLRLTFDTLGAQLVRAELLKYPATGQADKPTVLLDRTA 120 VP + + + + + TDVL LT +T G + +A L YP + +P LL+ + Sbjct: 50 QGVPASG-----QGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSP 104 Query: 121 GLNYVAQTGVVGAANGQNFPTHQTPFRVVSTDRQMTGD---SLAVAFE-AESGGVKVTKT 176 Y AQ+G+ G N P V D + + L V ++ G TKT Sbjct: 105 QFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKT 164 Query: 177 FTLHRGRYDIDVRHDLANVGAAPVTPALYLQLERDGNDP--ADTSS---FYHTFTGMAVY 231 F L RG Y ++V +++ N G P+ + + QL++ P DT S HTF G A Sbjct: 165 FVLKRGDYAVNVNYNVQNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFALHTFRGAAYS 224 Query: 232 SEQDKFQKMTFADIEKKKANYIKQADNGWIAVVQHYFATAWVPPQGKPRNNEVLEVQKNL 291 + +K++K F I + N + GW+A++Q YFATAW+P N + + Sbjct: 225 TPDEKYEKYKFDTIADNE-NLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGI 283 Query: 292 YAARTIEAVGEIAPGAAARVDSHLWVGPQDQKAMAALAPGLELVVDYGWLTIIAKPLFTL 351 A + PG ++S LWVGP+ Q MAA+AP L+L VDYGWL I++PLF L Sbjct: 284 AAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKL 343 Query: 352 MTWLHSILGNWGWTIVALTVLIKALFYPLAAASYRSMARMKQVAPRLQALKEKYGDDKQK 411 + W+HS +GNWG++I+ +T +++ + YPL A Y SMA+M+ + P++QA++E+ GDDKQ+ Sbjct: 344 LKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQR 403 Query: 412 LNAAMMEMYRTEKINPLGGCLPMLVQIPVFISLYWVLLASVEMRGAPWILWVHDLSIRDP 471 ++ MM +Y+ EK+NPLGGC P+L+Q+P+F++LY++L+ SVE+R AP+ LW+HDLS +DP Sbjct: 404 ISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDP 463 Query: 472 YFILPAIMMATMFLQIKLNPTP-PDPVQAKVMMIMPLVFGGMMFFFPAGLVLYWCVNNTL 530 Y+ILP +M TMF K++PT DP+Q K+M MP++F +FP+GLVLY+ V+N + Sbjct: 464 YYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLV 523 Query: 531 SIAQQWSITRAMQRKTEAAANR 552 +I QQ I R ++++ + + Sbjct: 524 TIIQQQLIYRGLEKRGLHSREK 545
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.8 bits (77), Expect = 3e-04 Identities = 14/75 (18%), Positives = 27/75 (36%), Gaps = 2/75 (2%) Query: 184 CVAGGMAVRDG--ELAGLFDVVTDPGQRRKGHAATLVDHLLALCVEDGATTAYLQVEPQN 241 G + +R A + D+ R+KG L+ + E+ L+ + N Sbjct: 75 NCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDIN 134 Query: 242 TAARALYGRYGFKDC 256 +A Y ++ F Sbjct: 135 ISACHFYAKHHFIIG 149
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 60.6 bits (147), Expect = 3e-12 Identities = 41/128 (32%), Positives = 58/128 (45%), Gaps = 2/128 (1%) Query: 29 LGLFLLLPVFAVAARGL-PGGDDPARVGLALGMYGLTQAFMQIPFGLASDRWGRRPVVLF 87 +G+ L++PV R L D A G+ L +Y L Q G SDR+GRRPV+L Sbjct: 19 VGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLV 78 Query: 88 GLLLFVAGSVVCAQADDVFWITIGRAIQG-AGAISAAVTAWLADATRDEVRTRAMAMVGG 146 L + A A ++ + IGR + G GA A A++AD T + R R + Sbjct: 79 SLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSA 138 Query: 147 SIGLSFAA 154 G A Sbjct: 139 CFGFGMVA 146
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 28.5 bits (63), Expect = 0.024 Identities = 19/75 (25%), Positives = 24/75 (32%) Query: 122 DTGADRYSTEIVADQMQMLGGREDGGGGGGSYGGGGGYDDAPARQPQQRAPAQRPAPQQR 181 D G RY + L G + + G P QP+ AP + Sbjct: 548 DIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELS 607 Query: 182 PAPQAAPAGGGANLA 196 A AA GG LA Sbjct: 608 AAANAAVNTGGVGLA 622
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 103 bits (257), Expect = 7e-26 Identities = 82/413 (19%), Positives = 155/413 (37%), Gaps = 37/413 (8%) Query: 27 VVLAAFDSTIISTTLPRVAEALDGM-ALYAWVGTGYLLTTAASILIFGRLGDMFGRKSLM 85 + + +++ +LP +A + A WV T ++LT + ++G+L D G K L+ Sbjct: 23 SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLL 82 Query: 86 LVSVLIVALGSIACGLAQSM-EQLIAFRSLQGIGGGMMIATAFAAPADLFPDARQRVRWM 144 L ++I GS+ + S LI R +QG G A A P R + Sbjct: 83 LFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKEN-RGKAF 141 Query: 145 ALISAAFAMASGIGPVLGGTATQVLGWRAAFFISPIAALAALALLARYFPRIPPPHAADR 204 LI + AM G+GP +GG + W I I Sbjct: 142 GLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMI--TIITVPFLMKLL--KKEVRIKG 197 Query: 205 RIDWIGAILLVAAVGAPLAALELAFAPGDSGQPMLALCLAFIGVAAIALLIPIERRLASP 264 D G IL+ + + F + + L ++ + + + + R++ P Sbjct: 198 HFDIKGIILMSVGI--------VFFMLFTTSYSISFLIVSVL---SFLIFVKHIRKVTDP 246 Query: 265 IFPLRVLASQEPRLLNLAATMVGAVMFVLIFYS--------PLLLQQVLGYTPSEAG-LL 315 +P L M+G + +IF + P +++ V + +E G ++ Sbjct: 247 FV--------DPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVI 298 Query: 316 LTPLVAAISVGSIINGRLYPKQSEPQRLMVFGSCLLATGTLAVLLISSATPAWWILAAFF 375 + P ++ + I G L ++ P ++ G L+ L + T W++ Sbjct: 299 IFPGTMSVIIFGYIGGILVDRRG-PLYVLNIGVTFLSVSFLTASFLLETTS-WFMTIIIV 356 Query: 376 INGCALGFLLPNLTLFMQLLSERRDIGVASALVQTTRAIGSALGTAIVGILIS 428 L F ++ + ++++ G +L+ T + G AIVG L+S Sbjct: 357 FVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 172 bits (438), Expect = 1e-53 Identities = 78/336 (23%), Positives = 135/336 (40%), Gaps = 38/336 (11%) Query: 3 RILVTGGAGFLGSHLCERLLNEGNDVLCVDN----YFTGNKDNIAHLMSNPHFEAMRHDV 58 + LVTG AGF+G H+ +RLL G+ V+ +DN Y K L++ P F+ + D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 59 T-------IPLYVEVDEIYNLACPASPVHYQF-DPVQTTKTSVHGAINMLGLAKRVKAK- 109 + + ++ + V Y +P +++ G +N+L + K + Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLA-VRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 110 ILQASTSEVYGDPEIHPQTEAYWGNVNPIGLRSCYDEGKRCAETLFFDYWRQYSVKIKVV 169 +L AS+S VYG P + + +P+ S Y K+ E + Y Y + + Sbjct: 121 LLYASSSSVYGLNRKMPFSTDDSVD-HPV---SLYAATKKANELMAHTYSHLYGLPATGL 176 Query: 170 RIFNTYGPRMHPNDGRVVSNFIVQALRGDDITIYGDGSQTRSFCYVDDLIEAFIRAMGTP 229 R F YGP P+ + F L G I +Y G R F Y+DD+ EA IR Sbjct: 177 RFFTVYGPWGRPD--MALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVI 234 Query: 230 DDFTGPV-----------------NIGNPAEFTMLELAEKVIALTGTASKIVFKPLPSDD 272 NIGN + +++ + + G +K PL D Sbjct: 235 PHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGD 294 Query: 273 PKQRQPNISLAKSAMNGWEPSVQLDQGLGKTIDYFR 308 + + + G+ P + G+ ++++R Sbjct: 295 VLETSADTKALYEVI-GFTPETTVKDGVKNFVNWYR 329
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 75.6 bits (186), Expect = 1e-17 Identities = 50/267 (18%), Positives = 94/267 (35%), Gaps = 42/267 (15%) Query: 6 SILITGGTGSFGKAFVRTVLERYPEVKRLVIFSR---DELKQFEMSQEFPEAKYPAVRYF 62 L+TG G G + +LE +V + + LKQ + P ++ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLEL----LAQPGFQFH 57 Query: 63 IGDVRDEARIRR--ALEGIDVVIHAAALKQVPAAEYNPFECIKTNVLGAQNLIEACLDSG 120 D+ D + A + V + V + NP +N+ G N++E C + Sbjct: 58 KIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK 117 Query: 121 VKRVVALST---------------DKAAAPINLYGATKLCSDKLFVAANNIKGNRDIRFS 165 ++ ++ S+ D P++LY ATK ++ + +++ G + + Sbjct: 118 IQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYG---LPAT 174 Query: 166 VVRYGNVLGSRGS---VVPFFLNKRKSGVLPIT---DSDMTR---FNISLQEGVDMVLWS 216 +R+ V G G + F G I M R + + E + + Sbjct: 175 GLRFFTVYGPWGRPDMALFKFTKAMLEGK-SIDVYNYGKMKRDFTYIDDIAEAIIRLQDV 233 Query: 217 I---ENAWGGEVLVPKIPS--YRVVDV 238 I + W E P YRV ++ Sbjct: 234 IPHADTQWTVETGTPAASIAPYRVYNI 260
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 29.8 bits (67), Expect = 0.015 Identities = 25/99 (25%), Positives = 37/99 (37%), Gaps = 1/99 (1%) Query: 134 LGALLAAVALVWLLNLYNFMDGIDGIAAAEAVCVCSGGAILYLLTGRPEAGYAPLLLAAA 193 L L + L + D + G A A + + S LLTG+ GY L AA Sbjct: 163 LPLLWGGLLFNLLGGFVSLGDAVIG-AMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAA 221 Query: 194 AAGFLCWNFPPAKIFMGDVGSGFLGITLGVLALQAGWTA 232 +L W P + + + F+GI L +L Sbjct: 222 LGAWLGWQALPIVLLLSSLVGAFMGIGLILLRNHHQSKP 260
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 77.5 bits (191), Expect = 1e-17 Identities = 55/298 (18%), Positives = 110/298 (36%), Gaps = 42/298 (14%) Query: 281 TVLVTGAGGSIGSELCRQLARFSPARLVLVEANEFALYNVEQWFHQHWPQLELVLLAGDV 340 LVTGA G IG + ++L + + N++ +++Q + Q D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 341 KDAARMEEVFQGWRPDVVFHAAAYKHVPLMEVANAWQAARNNVLGTLRVAECAVRYGASR 400 D M ++F + VF + V + N A +N+ G L + E Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVR-YSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 401 FVLIST---------------DKAVNPTNVMGATKRMAEMVCESLYRRHQTTQFSMVRFG 445 + S+ D +P ++ ATK+ E++ + Y + +RF Sbjct: 121 LLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHT-YSHLYGLPATGLRFF 179 Query: 446 NVLGSTGS---VIPKFQAQIARGGPVTV-THPEINRYFMSIPEAAQLVLQA--------- 492 V G G + KF + G + V + ++ R F I + A+ +++ Sbjct: 180 TVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADT 239 Query: 493 ---------ASMGAGGEIFVLDMGHPVKIVDLARNMIRLSGYSEAQIRIEFTGLRPGE 541 A+ A ++ + PV+++D + + G + + L+PG+ Sbjct: 240 QWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALG---IEAKKNMLPLQPGD 294
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 38.6 bits (90), Expect = 2e-05 Identities = 35/152 (23%), Positives = 54/152 (35%), Gaps = 21/152 (13%) Query: 57 IVIDVNSGQTLAASNPDMKVEPASLTKIMTAYVVFNALEEKRLTLEQTVPVSEHAWRTGG 116 I +D+ SG+TL A D + S K++ V ++ LE+ + + Sbjct: 43 IEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQD----- 97 Query: 117 SRMFIEPRKPVTVDELNQGM---------IVQSGNDASVALAEAVGGSEA--AFATLMNQ 165 + PV+ L GM I S N A+ L VGG AF + Sbjct: 98 ----LVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGD 153 Query: 166 EAERLGMRNTHFMNATGLPDPQHMTSTRDLAT 197 RL R +N D + T+ +A Sbjct: 154 NVTRLD-RWETELNEALPGDARDTTTPASMAA 184
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 159 bits (403), Expect = 5e-48 Identities = 85/352 (24%), Positives = 139/352 (39%), Gaps = 42/352 (11%) Query: 1 MSIIVTGGAGFIGSNFVLDWLSVKDEAVTTLDKLT--YAGNLENL-ASLAGDSRHSFIHG 57 M +VTG AGFIG + L + V +D L Y +L+ L F Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQ-VVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DIGDSRLVGDVLARHQPRAIINFAAESHVDRSIHAPAAFIQTNVVGTFQLLESVREYWSA 117 D+ D + D+ A + V S+ P A+ +N+ G +LE R Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN--K 117 Query: 118 LQEPARSNFRLLHVSTDEVYGSLDAHAAAFQETTAYAPNSPYAASKAASDHLMRAYHHTY 177 +Q LL+ S+ VYG L+ + + P S YAA+K A++ + Y H Y Sbjct: 118 IQ-------HLLYASSSSVYG-LNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLY 169 Query: 178 GLPILTTNCSNNYGPFHFPEKLIPLLIHHALAGKPLPIYGDGQQIRDWLYVKDHCSALRR 237 GLP YGP+ P+ + L GK + +Y G+ RD+ Y+ D A+ R Sbjct: 170 GLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIR 229 Query: 238 VLEAGR------------------PGQTYNVGGNNERTNLEVAHHICDLLDELQPRVDGR 279 + + P + YN+ GN+ L D + L+ + Sbjct: 230 LQDVIPHADTQWTVETGTPAASIAPYRVYNI-GNSSPVELM------DYIQALEDALGIE 282 Query: 280 SYRQQIVFVADRPGHDRRYAVDSRRLEQELNWTPAETFESGMLQTVRWYLAN 331 + + + +PG + D++ L + + +TP T + G+ V WY Sbjct: 283 A---KKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>NEISSPPORIN#Neisseria sp. porin signature. Length = 348 Score = 25.7 bits (56), Expect = 0.037 Identities = 15/37 (40%), Positives = 19/37 (51%) Query: 57 ALDLPAMTLVYDADPALLAKIKAGDKVRFTAERKDGK 93 AL L A+ + AD L IKAG + + E DGK Sbjct: 7 ALTLAALPVAAMADVTLYGAIKAGVQTYRSVEHTDGK 43
>adhesinb#Adhesin B signature. Length = 310 Score = 262 bits (671), Expect = 1e-88 Identities = 96/325 (29%), Positives = 163/325 (50%), Gaps = 35/325 (10%) Query: 13 ALLAAAGLWLSTAFGAAHAAEPLPVVASFSILGDIVREVGGDDIKLGTLVGPDGDAHEYE 72 A + A + +++ L VVA+ SI+ DI + + GD I L ++V D HEYE Sbjct: 13 AFVGLAACSSQKSSTETGSSK-LNVVATNSIIADITKNIAGDKINLHSIVPVGQDPHEYE 71 Query: 73 PTPGDAKKLAAARILFVNGLDFE----AWLPRLVKAAGFTG--PTVVASKGVTPRKFAGH 126 P P D KK + A ++F NG++ E AW +LV+ A S+GV G Sbjct: 72 PLPEDVKKTSQADLIFYNGINLETGGNAWFTKLVENAKKKENKDYYAVSEGVDVIYLEGQ 131 Query: 127 EHGTHDHGHGGKDHDHDHDHDHGAGEGHHHHGDADPHAWQNLANGVTYARNVAEGLAAAD 186 G DPHAW NL NG+ YA+N+A+ L+ D Sbjct: 132 SEK----------------------------GKEDPHAWLNLENGIIYAQNIAKRLSEKD 163 Query: 187 PAHADAYRKRADAYIARLQAADAAARKAFAAIPAERRKVVTSHDAFGYFGDAYGVDFIAA 246 PA+ + Y K AY+ +L A D A++ F IP E++ +VTS F YF AY V Sbjct: 164 PANKETYEKNLKAYVEKLSALDKEAKEKFNNIPGEKKMIVTSEGCFKYFSKAYNVPSAYI 223 Query: 247 MGVSTAAEPSAGDVARIIEQVKRDKVPAVFVENITSPRLVQQIARETGAKVGGTLYSDAL 306 ++T E + + ++E++++ KVP++FVE+ R ++ ++++T + +++D++ Sbjct: 224 WEINTEEEGTPDQIKTLVEKLRKTKVPSLFVESSVDDRPMKTVSKDTNIPIYAKIFTDSV 283 Query: 307 SKPGQPGATYLEMFEWNVRQLTAAL 331 ++ G+ G +Y M ++N+ ++ L Sbjct: 284 AEKGEEGDSYYSMMKYNLEKIAEGL 308
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 30.3 bits (68), Expect = 0.014 Identities = 14/36 (38%), Positives = 22/36 (61%), Gaps = 2/36 (5%) Query: 140 QATRWLELASY--ALVTLLGAWLVWIKAIRPLLRRR 173 Q + +L + L+ L+ AW++W KA+RP L RR Sbjct: 451 QQSFIDQLLAAGRWLLVLVVAWILWRKAVRPQLTRR 486
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 37.1 bits (86), Expect = 7e-05 Identities = 29/106 (27%), Positives = 39/106 (36%), Gaps = 7/106 (6%) Query: 138 GVVPIVNENDTVVTDEIRLGDNDTLGALVTNLIEADTLIILTDQRGLYDSDPRKNPDAKF 197 G VP++ E+ + E + D D G + + AD +ILTD G + Sbjct: 195 GGVPVILEDGEIKGVEAVI-DKDLAGEKLAEEVNADIFMILTDVNGAALYYGTEKEQWLR 253 Query: 198 MAHVQAGDPALEAMAGGAGSGIGTGGMLTKVLAAKRAAHSGAHTVI 243 V+ E AGS M KVLAA R G I Sbjct: 254 EVKVEELRKYYEEGHFKAGS------MGPKVLAAIRFIEWGGERAI 293
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 25.5 bits (56), Expect = 0.024 Identities = 9/31 (29%), Positives = 13/31 (41%) Query: 33 AGSIIVRQRGTRFHAGVNVGMGKDHTLFALV 63 AG II Q G F V+ + + A + Sbjct: 98 AGEIIGLQMGLSFATFVDPASHLNMPVLARI 128
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 46.7 bits (111), Expect = 3e-08 Identities = 59/254 (23%), Positives = 95/254 (37%), Gaps = 27/254 (10%) Query: 31 ARVSLSLRDL-DGGTVLAHHADRVQPSASIIKVPILLALLEAMANGRYALEQPLAL---- 85 RV + DL G T+ A AD P S KV + A+L + G LE+ + Sbjct: 38 GRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQD 97 Query: 86 -----PACGDRAGGTGILAQLPSVASLSLAELARLMIVLSDNAATNALIDLL-GFDAINQ 139 P +++ EL I +SDN+A N L+ + G + Sbjct: 98 LVDYSPVSEKHLADG-----------MTVGELCAAAITMSDNSAANLLLATVGGPAGLTA 146 Query: 140 WSQRAGLAASRLQRRMMDAAAREAGRDNFTSADDATAA-LCWMLRDGMLPSPLRTFALD- 197 + ++ G +RL R + G T+ + AA L +L L + + L Sbjct: 147 FLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQW 206 Query: 198 LLADQRERAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADRS--VVLAVLADGFTDW 254 ++ D+ + LPA +A K G G R +L +++ +V+ L D Sbjct: 207 MVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASM 266 Query: 255 QTAQTLQGGEGAAL 268 G GAAL Sbjct: 267 AERNQQIAGIGAAL 280
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 91.4 bits (227), Expect = 4e-23 Identities = 54/219 (24%), Positives = 90/219 (41%), Gaps = 28/219 (12%) Query: 1 MKILITGGAGFLGQRLARKLLEQGRLALSGERVPISQID-----LLDVTRTDAINDTRVR 55 MK L+TG AGF+G ++++LLE G + V I ++ L R + + + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGH-----QVVGIDNLNDYYDVSLKQARLELLAQPGFQ 55 Query: 56 SVEGDVADPDCLRSLIG-ADTAVIFHLAAIVSGQAEADFDLG-----MRINLDASRALLE 109 + D+AD + + L +F + + L NL +LE Sbjct: 56 FHKIDLADREGMTDLFASGHFERVFISPH----RLAVRYSLENPHAYADSNLTGFLNILE 111 Query: 110 ACRRQGHRPRVVFTSSVAVYGGA--LPETVRDDTALNPQSSYGTQKAIAELLLADYTRRG 167 CR + +++ SS +VYG +P + DD+ +P S Y K EL+ Y+ Sbjct: 112 GCRHNKIQ-HLLYASSSSVYGLNRKMPFST-DDSVDHPVSLYAATKKANELMAHTYSHLY 169 Query: 168 FVDGRALRLPTISVRPGRPNAAASSFASGIIREPLNGEP 206 + LR T+ GRP+ A F + L G+ Sbjct: 170 GLPATGLRFFTVYGPWGRPDMALFKFTKAM----LEGKS 204
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 31.2 bits (70), Expect = 0.002 Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 5/49 (10%) Query: 186 EARHADQMRAVLREHEAIAEAIRRQDEDAAREAARI-HMVNAAKRLRLA 233 EARHA+ A +R+ AI E R RE I +VN A LR Sbjct: 55 EARHAEAFPADVRDSAAIDEITAR----IEREMGPIDILVNVAGVLRPG 99
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.5 bits (66), Expect = 0.029 Identities = 24/143 (16%), Positives = 54/143 (37%), Gaps = 15/143 (10%) Query: 78 VGGMLIGSYADRHGRRAAMTLTLWLMGLGCALIAAAPTHAQMGLLGPVMMVLARLIQGFA 137 +G + G +D+ G + + + + G + H+ LL ++AR IQG Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGS--VIGFVGHSFFSLL-----IMARFIQGAG 116 Query: 138 AGGEVGASTTLLVEHAPPSRRGFYSSWQFGSQSLGVALGAVVVGTLTAALSAEQMQAWGW 197 A ++ + P RG ++G +G + G + + W Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI--------HW 168 Query: 198 RVPFVIGILTVPVGAYIRRNLEE 220 +I ++T+ ++ + L++ Sbjct: 169 SYLLLIPMITIITVPFLMKLLKK 191
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 31.7 bits (72), Expect = 0.011 Identities = 19/125 (15%), Positives = 33/125 (26%), Gaps = 14/125 (11%) Query: 575 VEGELRHQFTP---VFSAAVFGDYVRGKLTGGDGNLPRIPA-------ARAGLRGNVKWQ 624 + L H ++ D R G N+ + A A + L + + Sbjct: 396 FQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHD 455 Query: 625 QWSGGIEYARVFSQKD----IAAYESSTPGYNLVNAVVAYRGRYGATGYEVYLRGTNLLN 680 S Y + ++ + Y ST GY R + + Sbjct: 456 GQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKF 515 Query: 681 KLAYN 685 YN Sbjct: 516 TDYYN 520
>PF06580#Sensor histidine kinase Length = 349 Score = 29.1 bits (65), Expect = 0.021 Identities = 16/102 (15%), Positives = 34/102 (33%), Gaps = 5/102 (4%) Query: 63 IALYGVTLACMNLLFYMALRTLPLGVAIAIEFTGPLTLAVVLSRRAIDFVWIACALAGLV 122 ++ + ++ M L+ A R+ G + L V+ + I VW + Sbjct: 41 SMIFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQIILRVLPACVVIGMVWFVANTSIWR 100 Query: 123 LLIPTGQSMHDLDPVGIAYALGAAVCWALYIIFGKMAGNVHG 164 LL PV L ++ + + ++ + G Sbjct: 101 LLAFINTK-----PVAFTLPLALSIIFNVVVVTFMWSLLYFG 137
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 103 bits (259), Expect = 6e-26 Identities = 86/405 (21%), Positives = 157/405 (38%), Gaps = 17/405 (4%) Query: 16 VCLAALMFGLEISSVPVILPTLEQALHSGFQELQWIMNAYTIACTTVLMAAGTLADRYGR 75 +C+ + L + V LP + + W+ A+ + + G L+D+ G Sbjct: 19 LCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGI 78 Query: 76 KRLLLASLAVFGLTSLVCGWAQDT-GVLIAGRALQGLSGGAMLICQVAVLSHRFQDGAAR 134 KRLLL + + S++ +LI R +QG +G A V V+ R+ R Sbjct: 79 KRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQG-AGAAAFPALVMVVVARYIPKENR 137 Query: 135 GRAFGAWGIAFGVGLGFGPVIGSAIVAVASWQWVFLAHGPLALIALGLAWKGVDESRDPR 194 G+AFG G +G G GP IG I W ++ L P+ I + + Sbjct: 138 GKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLI--PMITIITVPFLMKLLKKEVRI 195 Query: 195 QRKLDVAGIVSLSVAVFGLAWFITQGPSAGFASLATLASLGAAIVALVVFVIAERRCADP 254 + D+ GI+ +SV + F T S F + ++++ ++FV R+ DP Sbjct: 196 KGHFDIKGIILMSVGIVFFMLFTTSY-SISFLIV--------SVLSFLIFVKHIRKVTDP 246 Query: 255 MFDFAVFRIRRFSGALLASAAMNFSFWPFMIYLPLYFQNGLGYGGLGTGLS-LLAYTLPT 313 D + + F +L + + F+ +P ++ G + T+ Sbjct: 247 FVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSV 306 Query: 314 LVAPPLGEKLALRYRPDTVIPAGLFAICLGFALMKWGSGVAQASWLTMLPGCLLAGTGLG 373 ++ +G L R P V+ G+ + + F + SW + + G GL Sbjct: 307 IIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTA--SFLLETTSWFMTIIIVFVLG-GLS 363 Query: 374 LINTPVTNTTTGAVPGDRAGMASGIDISVRMISLSINIALMGFLL 418 T ++ + ++ AG + +S IA++G LL Sbjct: 364 FTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 70.2 bits (172), Expect = 2e-16 Identities = 33/156 (21%), Positives = 60/156 (38%), Gaps = 4/156 (2%) Query: 11 RVLLADDHGIVREGLKMVLQQAPAMIGSIDEAATGEQVLALLAAHGADVLVLDLGMPGVA 70 +L+ADD +R L L +A + + + +AA D++V D+ MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGY---DVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 71 GSGWVRALRDRHPALHIMVLTANTDARSRQAILEAGADAYLAKTGSSHELMAAIQR-LHQ 129 + ++ P L ++V++A + E GA YL K EL+ I R L + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 130 DPADRPVRARPNHTPAPADTLTRREQQVLALAAQGA 165 + P + Q++ + A+ Sbjct: 122 PKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLM 157
>PF06580#Sensor histidine kinase Length = 349 Score = 41.4 bits (97), Expect = 5e-06 Identities = 41/191 (21%), Positives = 73/191 (38%), Gaps = 40/191 (20%) Query: 258 ARRQQTVLDSLNRLLDGLLDVSRMDAHLLRIE----RRAVDLDQL-FDDIRLDFESLARA 312 + + +L SL+ L+ L S L E + L + F+D RL FE Sbjct: 190 PTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFED-RLQFE----- 243 Query: 313 RGLRLSVAPTSLALDTDPALLRRILDNLLTNALSYTPKGG-VLLSARRRRGGVLIQVWDT 371 + P + + P L++ +++N + + ++ P+GG +LL + G V ++V +T Sbjct: 244 ----NQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENT 299 Query: 372 GVGIAPELQEAVFTEFTRGAGAPASPPAGQGLGLGLAIVRRLAGLLHGE---ITLRSTPG 428 G + G GL VR +L+G I L G Sbjct: 300 GSLALKN--------------------TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQG 339 Query: 429 KGSVFSLWLPA 439 K + + +P Sbjct: 340 KVNAM-VLIPG 349
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 36.0 bits (83), Expect = 3e-04 Identities = 29/129 (22%), Positives = 58/129 (44%), Gaps = 4/129 (3%) Query: 65 LTWGVVQPFTGMIADRHGSAKVILGGLACYALGLAGMAHAGTVTAFMLSAGVCIGIALSG 124 LT+ + G ++D+ G +++L G+ G + + ++ A G Sbjct: 60 LTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAG--A 117 Query: 125 TAF-AVIYGALSRLVPPERRGWALGVAGAVGGLGQFTMVPAAQWLIGSRGWVDALLIFAV 183 AF A++ ++R +P E RG A G+ G++ +G+ + PA +I LL+ + Sbjct: 118 AAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGE-GVGPAIGGMIAHYIHWSYLLLIPM 176 Query: 184 VLAVVVPLA 192 + + VP Sbjct: 177 ITIITVPFL 185
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 90.9 bits (225), Expect = 9e-24 Identities = 65/254 (25%), Positives = 103/254 (40%), Gaps = 15/254 (5%) Query: 18 LTGQRVIVTAGAAGIGAAIAGAFAARGAQVHICDVDERALAACPHPWS---------RAD 68 + G+ +T A GIG A+A A++GA + D + L AD Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 69 VSQRDQIDRYMQEALARLGGLDVLVNNAGIAGPTAGIADIAPQELDATLDINLASQFHTV 128 V ID +G +D+LVN AG+ P I ++ +E +AT +N F+ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGL-IHSLSDEEWEATFSVNSTGVFNAS 124 Query: 129 RHALPALRQAGGGSIINISSVAGRMGVPMRTPYAATKWGVVGLTRSLAVELGGYGIRVNA 188 R + GSI+ + S + YA++K V T+ L +EL Y IR N Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 189 LLPGL--VAGPRIDRVIEARARNMGVTVAEETRLELAGVSLGQFVRAADIANMALFLASP 246 + PG E A + E + G+ L + + +DIA+ LFL S Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKT---GIPLKKLAKPSDIADAVLFLVSG 241 Query: 247 FGAMVSGQAISIDG 260 ++ + +DG Sbjct: 242 QAGHITMHNLCVDG 255
>cdtoxina#Cytolethal distending toxin A signature. Length = 258 Score = 28.9 bits (64), Expect = 0.045 Identities = 14/40 (35%), Positives = 18/40 (45%), Gaps = 1/40 (2%) Query: 276 SDTSPSPQPQPTAMSDNGTSLPTSKP-PPARPGTPPPSAL 314 T PSP + G +LPT+ P PGT P +L Sbjct: 43 GPTVPSPDEPGLPLPGPGPALPTNGAIPIPEPGTAPAVSL 82
>PF06438#Heme acquisition protein HasAp Length = 205 Score = 62.7 bits (152), Expect = 2e-14 Identities = 44/140 (31%), Positives = 65/140 (46%), Gaps = 19/140 (13%) Query: 37 GEHTGVPNSGGFFGGGFFSGTEYGYTSKTVDGYAFVASGDLNYYFPPFSGPKMEGATPHT 96 G+ N+GGF G F G++Y S D AF+A GDL+Y FS P HT Sbjct: 35 GQVVDGSNTGGFNPGPF-DGSQYALKSTASD-AAFIAGGDLHYTL--FSNPS------HT 84 Query: 97 LWGTLESVTLGAGVDKAG-----HVVDPFITFTFDDPLHGDLADGRGNVTHDIIWGLMNG 151 LWG L+S+ LG + + ++F+ L +A GR H +++GLM+G Sbjct: 85 LWGKLDSIALGDTLTGGASSGGYALDSQEVSFSNLG-LDSPIAQGRDGTVHKVVYGLMSG 143 Query: 152 ---SVEGADDKLGSGTHGGL 168 +++G D L L Sbjct: 144 DSSALQGQIDALLKAVDPSL 163
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 391 bits (1006), Expect = e-135 Identities = 93/418 (22%), Positives = 155/418 (37%), Gaps = 6/418 (1%) Query: 33 ARFGWWVLALGFGGFLAWAAWAPLDNGVAMPGIVVVTGERQAVDSIEGGVVSALLVAEGD 92 R + + + ++ G + +G + + IE +V ++V EG+ Sbjct: 57 PRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGE 116 Query: 93 PVRAGQALVRLDDTRVRGEARSLRAQQAAVMAREARLLAERDGRDDLAPPDAQANAEAAV 152 VR G L++L + ++ + R + P+ + E Sbjct: 117 SVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYF 176 Query: 153 AYAME------RQLFASRRAALAGELAGIEATLAGSRALAGGLESTLAHKRTQRALLREQ 206 E L + + + E L RA + + + + + + Sbjct: 177 QNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSR 236 Query: 207 LGNLRDLAREGYVPRNRVLELERSLAQLDGDLASDLGALGQTRQQIAELALRGQQRRDAF 266 L + L + + ++ VLE E + +L L Q +I Q F Sbjct: 237 LDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLF 296 Query: 267 QREVRTDLAETRVQREQLTQKLATAEFDLAHSEIRAPVSGTVVALATHTVGGVVQPGSRL 326 + E+ L +T LT +LA E S IRAPVS V L HT GGVV L Sbjct: 297 KNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL 356 Query: 327 MEIVPEDVPLVVEGRLPVESIDKVRAGLPVELMFTAFDASRTPRLEGTVTLVSADRFEDD 386 M IVPED L V + + I + G + AF +R L G V ++ D ED Sbjct: 357 MVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQ 416 Query: 387 RNGRPYYRLRADVAPGQLRRIGDAPLRAGMPVEVFVRTGERSLLNYLFKPLLDRARLA 444 R G + + + + PL +GM V ++TG RS+++YL PL + + Sbjct: 417 RLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLEESVTES 474
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 169 bits (431), Expect = 3e-52 Identities = 79/346 (22%), Positives = 134/346 (38%), Gaps = 48/346 (13%) Query: 16 RILIAGAASLVGSHTADALLAAGVREVILLDNFA----FGTPEAIAHLQGNPRVKVVRGD 71 + L+ GAA +G H + LL AG +V+ +DN +A L P + + D Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 72 LMRLPDL--LAATEGVDGVLHLAAYMTLGFA-QTPWQAVDVNIRGAQNMLEACRANKVKK 128 L + L A+ + V + + ++ + P D N+ G N+LE CR NK++ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 129 FVFASSNAVYGYGSGIAGALAENGPF---HSVGAPPAAILYGASKIMGEQLCRQYYQKAG 185 ++ASS++VYG L PF SV P LY A+K E + Y G Sbjct: 121 LLYASSSSVYG--------LNRKMPFSTDDSVDHP--VSLYAATKKANELMAHTYSHLYG 170 Query: 186 LDYVVLRYSTVYGERQHYRAANSLYIMETYDRVRQGERPVLPGDGTDTKHFVHVSDVARA 245 L LR+ TVYG A + + +G+ + G + F ++ D+A A Sbjct: 171 LPATGLRFFTVYGPWGRPDMALFKFT----KAMLEGKSIDVYNYGKMKRDFTYIDDIAEA 226 Query: 246 NVAAFQSDATDVA------------------VNVSGPAPITTGELVRLVLDYCKSDLEPE 287 + N+ +P+ + ++ + D + + Sbjct: 227 IIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKN 286 Query: 288 IRPDPPGTVRLTSGGAFHIPHDLAGQQIGWQPQVGMAEGVTRLLAW 333 + P PG V T + IG+ P+ + +GV + W Sbjct: 287 MLPLQPGDVLET-----SADTKALYEVIGFTPETTVKDGVKNFVNW 327
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 32.6 bits (74), Expect = 0.007 Identities = 18/55 (32%), Positives = 24/55 (43%), Gaps = 3/55 (5%) Query: 537 DDIYKNI--DYIIGSSYDDIIVGDMLGGVTMTGGAGNDTFVLHGGGNRVIFNDGD 589 D I N D + G +D + G G + GG GND + G N + DGD Sbjct: 747 DLIEGNDGNDRLYGDKGNDTLSGGN-GDDQLYGGDGNDKLIGVAGNNYLNGGDGD 800
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 122 bits (307), Expect = 5e-36 Identities = 78/249 (31%), Positives = 111/249 (44%), Gaps = 10/249 (4%) Query: 5 RTALVTGGTGCLGRAIARALLDAGHDVIVTCHASEAATRQWLDQEAAAGRRYDMVKVDVA 64 + A +TG +G A+AR L G + + E + + A R + DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKV-VSSLKAEARHAEAFPADVR 67 Query: 65 DYDACQALARRLADDGRQIDILVNNAGITRDASLRKMSYENWNDVLRSNLDSMFNMTQPL 124 D A + R+ + IDILVN AG+ R + +S E W N +FN ++ + Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 125 CGPMADRGWGRIVNISSVNGSKGAFGQTNYAASKAGIHGFTKSLALELARKGVTVNTVSP 184 M DR G IV + S YA+SKA FTK L LELA + N VSP Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 185 GYLATRMVEAV------PEDVLK---EKILPQIPLGRLGQPDEIAALVAFICSDAAAFMT 235 G T M ++ E V+K E IPL +L +P +IA V F+ S A +T Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 236 GSNVAMNGG 244 N+ ++GG Sbjct: 248 MHNLCVDGG 256
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 57.6 bits (139), Expect = 1e-11 Identities = 46/176 (26%), Positives = 73/176 (41%), Gaps = 5/176 (2%) Query: 197 AALIREREHGTIEHLLVMPVTPTEIMLAKV-WSMGLVVLVSAGLSLTFVVRGLLQVPVEG 255 AA R T E +L + +I+L ++ W+ L AG+ + G Q Sbjct: 89 AAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGYTQWL--- 145 Query: 256 SVALFLAGVALHLFATTSMGIFMATLARSMPQFGMLLVLVLLPLQMLSGGTTPRESMPDF 315 S+ L +AL A S+G+ + LA S F LV+ P+ LSG P + +P Sbjct: 146 SLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIV 205 Query: 316 VQNIMLAAPTTHFVELGQAILFRGAGLGVVWQPFLALALIGSVLFAFSLTRFRKTL 371 Q P +H ++L + I+ + V Q AL + + F S R+ L Sbjct: 206 FQTAARFLPLSHSIDLIRPIMLGHPVVDVC-QHVGALCIYIVIPFFLSTALLRRRL 260
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 70.2 bits (172), Expect = 2e-15 Identities = 65/391 (16%), Positives = 131/391 (33%), Gaps = 84/391 (21%) Query: 11 LLAIVAVAAAGYYGWRMLSDTGPGAGFVSGNGRIEATEVDVATKLAGRVQDVLVAEGDFV 70 + V A + G ++ +GR + + V++++V EG+ V Sbjct: 63 FIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKE----IKPIENSIVKEIIVKEGESV 118 Query: 71 SAGQPLARM------------QIDTLQAQREEAR-------------------------- 92 G L ++ Q LQA+ E+ R Sbjct: 119 RKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQN 178 Query: 93 AQHQQAVNNAASASAQVAQRESDKLAAEAVVVQRESELDAARRRLARSE----------- 141 ++ + + Q + ++ K E + ++ +E R+ R E Sbjct: 179 VSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLD 238 Query: 142 ---TLSREGASSIQELDDDRARVRSAQAAVNAGRAQVKAAQAAIDAAKAAQVG------- 191 +L + A + + + + A + ++Q++ ++ I +AK Sbjct: 239 DFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN 298 Query: 192 ------AQSAVNAALAT--IARIEADIADSELRAPRDGRV-QYRVAQAGEVLGAGGKVLN 242 Q+ N L T +A+ E S +RAP +V Q +V G V+ ++ Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358 Query: 243 MVDLADVY-MTFFLPEQAAGRVALGQDVRIVLDAAPQY---VIPAKVSFVASTAQFTPKT 298 +V D +T + + G + +GQ+ I ++A P + KV + A Sbjct: 359 IVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA------ 412 Query: 299 VETATERQKLMFRVKAQIAPELLRQHLRQVK 329 +R L+F V I L + + Sbjct: 413 --IEDQRLGLVFNVIISIEENCLSTGNKNIP 441
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.9 bits (75), Expect = 0.003 Identities = 22/171 (12%), Positives = 44/171 (25%), Gaps = 36/171 (21%) Query: 86 DLRTALLRVEEARALYGIQRADQFPTIGAQADGSRGRTPGDLNLTGQPQVASQYQVGVGM 145 L A L + L ++ P + + P N++ + + Sbjct: 142 SLLQARLEQTRYQILSRSIELNKLPELKLPDE------PYFQNVSEEEVL---------- 185 Query: 146 AAWELDFWGRVRSLKDAALENYLASDAAAEAATLSLIAQVADSYLTLRELDERLALTRAT 205 R+ SL + E A+ + R+ Sbjct: 186 ---------RLTSLIKEQFSTWQNQKYQKELNLDKKRAERL-------TVLARINRYENL 229 Query: 206 IASREESLRIFRRRYEVGSISKLDLTQVE----TLWQQARALGADLEQARA 252 + L F +I+K + + E + R + LEQ + Sbjct: 230 SRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIES 280
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 356 bits (915), Expect = e-121 Identities = 167/476 (35%), Positives = 260/476 (54%), Gaps = 8/476 (1%) Query: 3 IQAAWDLLRRYAMVFHHAWSQRRQEDDVPLDRHEREFLPANLELMETPAHPAAHLTMRAI 62 + + L RY +V+ W R+Q D ++ E EFLPA+LEL+ETP L I Sbjct: 5 LMGFSEFLLRYKLVWSETWKIRKQLDTPVREKDENEFLPAHLELIETPVSRRPRLVAYFI 64 Query: 63 LLLIVVILLIAVFGRLDIVAVAKGKLIPSERVKTIQPAITGVVKGILVRDGERVVAGQPL 122 + +V+ +++V G+++IVA A GKL S R K I+P +VK I+V++GE V G L Sbjct: 65 MGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVL 124 Query: 123 IVLDATQAAADADKARSQRIDASLAAARAKALLEAQAEQRQPQVRQVEDTTAEKQSEAQR 182 + L A A AD K +S + A L R + L + + P+++ ++ + SE + Sbjct: 125 LKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEV 184 Query: 183 FATAV-----YQEYTDKLSVAQAELERREAELATTRRLIRKLEITVPIARREADDYKELA 237 + + ++ + L+++ AE T I + E + + DD+ L Sbjct: 185 LRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLL 244 Query: 238 RDRYVAQHDYLDKTKQAVEQEHELSMQRSRATELAAAIDQQRAVLSQTASQFRREQLRDL 297 + +A+H L++ + VE +EL + +S+ ++ + I + F+ E L L Sbjct: 245 HKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKL 304 Query: 298 EQSSQQALQSRNDETKANTRQQLLTLHAPVGGVVQQSAVHTLGGVVTTAQSLMVIVPED- 356 Q++ + K RQQ + APV VQQ VHT GGVVTTA++LMVIVPED Sbjct: 305 RQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDD 364 Query: 357 VLEVEAHIENKDVGFVNEGDDTIVKIDAFPYTRYGYLTGKVVSVSSDAVQHRDRRAALTF 416 LEV A ++NKD+GF+N G + I+K++AFPYTRYGYL GKV +++ DA++ D+R L F Sbjct: 365 TLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIE--DQRLGLVF 422 Query: 417 TARIRLQTNQMLIDGKSINLTPGMEVSAEIKTGKRAVAAYFFDPLLQVAQESMRER 472 I ++ N + K+I L+ GM V+AEIKTG R+V +Y PL + ES+RER Sbjct: 423 NVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLEESVTESLRER 478
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 64.6 bits (157), Expect = 5e-12 Identities = 69/308 (22%), Positives = 112/308 (36%), Gaps = 72/308 (23%) Query: 1189 DDIFDGKGGDDVISGGGGNDVFLFERG-YGRLTIDQYRWSDQHRSTLRFGAGIGAADVAV 1247 D +F G I G G+DV +++ G LTID + ++ T+ Sbjct: 621 DKVFLS-AGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVT------------ 667 Query: 1248 SALGDPFGGSIALTMGADRVVLKGMALGVPGFGVQLIQFAD-------GTSWTAEQILAA 1300 G L + V+K + V G + Q+ G + T L + Sbjct: 668 ---RVLGGDVKVL-----QEVVKEQEVSV-GKRTEKTQYRSYEFTHINGKNLTETDNLYS 718 Query: 1301 ARDVRGTADSEILYGTPWDDVFRGNGGNDVLFGNGGNDVFLFEKGDGQIEIVARSYVKVN 1360 ++ GT ++ +G+ + D+F G G+D++ GN GND +KG+ Sbjct: 719 VEELIGTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGN-------------- 764 Query: 1361 NVVRLGAGIQVEDVSVTMSRDGEYDIFLNIGSDRIKLKKAGQVSLADAPTGFDLSVPRIE 1420 + + G G D L G KL + + G D + Sbjct: 765 DTLSGGNG----------------DDQLYGGDGNDKLIGVAGNNYLNGGDGDD----EFQ 804 Query: 1421 FADGTVWAPEHLLDLARRFEGNSGDDNLVGTYGADRFDGHGGDDYIAGHGGGDTFIFNQG 1480 ++ G G+D L G+ GAD DG GDD + G G D + + G Sbjct: 805 VQGNSLAKNVL--------FGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSG 856 Query: 1481 YGRLVIDE 1488 YG +ID+ Sbjct: 857 YGHHIIDD 864 Score = 62.7 bits (152), Expect = 1e-11 Identities = 77/338 (22%), Positives = 126/338 (37%), Gaps = 48/338 (14%) Query: 1842 GNDYIFGGGGGDTFIYKPGYGHLEI-YENDYAGTNTLKFGTGIDPGMMRIKGNSTSGIEI 1900 G+D +F G + G GH + Y+ G T+ + G + +++ Sbjct: 619 GDDKVFLSAG--SANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGGDVKV 676 Query: 1901 I-DRISGGKVTLTNAMYGAGYGLQRVEFSDGTVWTASQLRSAVSNAVATTEDDALFGTEV 1959 + + + +V++ Y +G T + +V + TT D FG++ Sbjct: 677 LQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFFGSKF 736 Query: 1960 AEVFDGLGGGDYIQGGGGGDTFHYKVGYGRLEILEVESAGATNVLKFGPGISASSMQVVG 2019 ++F G G D I+G G D + G L S G + +G + + V G Sbjct: 737 TDIFHGADGDDLIEGNDGNDRLYGDKGNDTL------SGGNGDDQLYGGDGNDKLIGVAG 790 Query: 2020 ADDLSITLKTGATGDAVVLSMAMSPAAGVQRIDFEDGTSWTGDDVRALLRRATTGNDVLF 2079 + L+ G GD D G+ + + GND L+ Sbjct: 791 NNYLN-----GGDGD--------------------DEFQVQGNSLAKNVLFGGKGNDKLY 825 Query: 2080 GSLLGPDRLDGLGGIDTVYGNGGNDTYVLGAGYGGQLTIFNGYMYGGADGKLEL-DVSAD 2138 GS G D LDG G D + G GND Y +GYG + GG + KL L D+ Sbjct: 826 GSE-GADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHII----DDDGGKEDKLSLADIDFR 880 Query: 2139 RLWLQRSGQDL-------KVSIMGTDASAVLRDWYKDD 2169 + +R G DL V +G R+W++ + Sbjct: 881 DVAFKREGNDLIMYKGEGNVLSIGHKNGITFRNWFEKE 918 Score = 60.0 bits (145), Expect = 1e-10 Identities = 46/178 (25%), Positives = 67/178 (37%), Gaps = 39/178 (21%) Query: 1694 IGSSGNDALTGTSDADYFDGQGGDDTVNGMGGGDTIIFNAGYGKLRISEPYWPALPENVV 1753 IG++ D G+ D F G GDD + G G D + + G N Sbjct: 723 IGTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKG----------------NDT 766 Query: 1754 VLGAGLSTAAAQIKALRNGDISLTFAGTSDQITFAATALFGGVGIPAIVFADGT---RWS 1810 + G NGD L +D+ L G G + DG + Sbjct: 767 LSGG-------------NGDDQLYGGDGNDK-------LIGVAGNNYLNGGDGDDEFQVQ 806 Query: 1811 GAEVFNAAMQLTPGDDVLFGNSSAEYFDGLGGNDYIFGGGGGDTFIYKPGYGHLEIYE 1868 G + + G+D L+G+ A+ DG G+D + GG G D + Y GYGH I + Sbjct: 807 GNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDD 864 Score = 59.6 bits (144), Expect = 1e-10 Identities = 54/191 (28%), Positives = 71/191 (37%), Gaps = 28/191 (14%) Query: 801 IVGTSAGEVLDGGGGNDYILGGGGADTYLFNAGYGLLTINQAEGAPGVISRLRFGAGIDA 860 ++GT+ + G D G G D N G L ++ L G G D Sbjct: 722 LIGTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGN------DTLSGGNGDDQ 775 Query: 861 RDITVKSDATGNLILLHANGTDKVVLELQASRPKYGVGVVEFADGSTWTRQQLLQMSLTG 920 GN L+ G + + G + S L G Sbjct: 776 LY-----GGDGNDKLIGVAGNNYLN-------GGDGDDEFQVQGNSLAKNV------LFG 817 Query: 921 SGAMDNIYGTTGADFIDGKGGTDYLKGRGGNDIFYYASGYGHVIIDEEDFARDAQNVLRF 980 D +YG+ GAD +DG G D LKG GNDI+ Y SGYGH IID++ D L Sbjct: 818 GKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDDDGGKEDK---LSL 874 Query: 981 GAGISLTDLRF 991 A I D+ F Sbjct: 875 -ADIDFRDVAF 884 Score = 58.4 bits (141), Expect = 3e-10 Identities = 45/177 (25%), Positives = 60/177 (33%), Gaps = 52/177 (29%) Query: 1439 FEGNSGDDNLVGTYGADRFDGHGGDDYIAGHGGGDTFIFNQGYGRLVIDEFARSANEVNV 1498 F G GDD + G G DR G G+D ++G G D G +L Sbjct: 740 FHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKL-------------- 785 Query: 1499 LRFGTGIAPQEVSMKIDEQGNVVMIIGTDQVVLSNMAAGLERNGVQRVEFADGTTWTRQQ 1558 I GN + G +G + + Sbjct: 786 ---------------IGVAGNNYLNGG---------------DGDDEFQVQGNSLAKNV- 814 Query: 1559 IHDRLRTIQGDAGGQTLYGTDLADRIDGGGGPDVLYGKEGDDTYVYKLGYGIMTIAD 1615 + G G LYG++ AD +DGG G D+L G G+D Y Y GYG I D Sbjct: 815 -------LFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDD 864 Score = 56.1 bits (135), Expect = 2e-09 Identities = 73/318 (22%), Positives = 120/318 (37%), Gaps = 62/318 (19%) Query: 950 GNDIFYYASGYGHVIIDEEDFARDAQNVLRFGAG--ISLTDLRFSVTSDGDVTITHGVPG 1007 G+D + ++G ++ +A +V+ + LT T G+ T+T + G Sbjct: 619 GDDKVFLSAGSANI------YAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGG 672 Query: 1008 DEIVIRNMAGWDYSGVQR-----------LEFANGESISKPDFLARTQY--GSSGSDTLY 1054 D V++ + V + NG+++++ D L + G++ +D + Sbjct: 673 DVKVLQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFF 732 Query: 1055 GSRYVDSIDGLGGDDTVYARGGGGDVFVFNQGYGHLTIDSYDALRSDMSTLKLGPGILAT 1114 GS++ D G GDD + N G L D + TL G G Sbjct: 733 GSKFTDIFHGADGDDLIEG----------NDGNDRLYGDKGN------DTLSGGNG---- 772 Query: 1115 NIQIRLSGPGGQDISVLMGTDTVTLIGMGADPSRSGVDRILFSDGTILNAAEVAARAHQI 1174 +L G G D LIG+ + +G D + + + Sbjct: 773 --DDQLYGGDGND----------KLIGVAGNNYLNGGD-----GDDEFQVQGNSLAKNVL 815 Query: 1175 SGSAGSDTLTGTLVDDIFDGKGGDDVISGGGGNDVFLFERGYGRLTIDQYRWSDQHRSTL 1234 G G+D L G+ D+ DG GDD++ GG GND++ + GYG ID L Sbjct: 816 FGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDD---DGGKEDKL 872 Query: 1235 RFGAGIGAADVAVSALGD 1252 A I DVA G+ Sbjct: 873 SL-ADIDFRDVAFKREGN 889 Score = 53.4 bits (128), Expect = 1e-08 Identities = 81/380 (21%), Positives = 117/380 (30%), Gaps = 101/380 (26%) Query: 1383 EYDIFLNI-GSDRIKLKKAGQVSLADAPTGFDLS--VPRIEFADGTVWAPEHLLDLARRF 1439 EY L + G D+ +K D +D S + + R Sbjct: 566 EYITELLVKGVDKWTVKGVQ-----DKGAVYDYSNLIQHASVGNNQY--------REIRI 612 Query: 1440 EGNSGDDNLVGTYGADRFDGHGGDDYIAGHGGGDTFIFNQG-YGRLVID-EFARSANEVN 1497 E + GD + A + + G G D +++ G L ID A A Sbjct: 613 ESHLGDGDDKVFLSAGSANIYAGK-------GHDVVYYDKTDTGYLTIDGTKATEAGNYT 665 Query: 1498 VLRFGTG--------IAPQEVSM-----KIDEQGNVVMIIGTDQVVLSNMAAGLER--NG 1542 V R G + QEVS+ K + I + ++ +E Sbjct: 666 VTRVLGGDVKVLQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGT 725 Query: 1543 VQRVEFADGTTWTRQQIHDRLRTIQGDAGGQTLYGTDLADRIDGGGGPDVLYGKEGDDTY 1602 + +F D I+G+ G LYG D + GG G D LYG +G+D Sbjct: 726 TRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKL 785 Query: 1603 VYKLGYGIMTIADGEFGVDAANVLEFGAGIDASMITAKAGLDGSLTLLLGPSGGAVVLQN 1662 GV N L G G D + G + +N Sbjct: 786 ---------------IGVAGNNYLNGGDGDDEFQV-----------------QGNSLAKN 813 Query: 1663 MLRGRYWGVQEVKFADGVHWNRDDVLALISTIGSSGNDALTGTSDADYFDGQGGDDTVNG 1722 +L G GND L G+ AD DG GDD + G Sbjct: 814 VLFG-----------------------------GKGNDKLYGSEGADLLDGGEGDDLLKG 844 Query: 1723 MGGGDTIIFNAGYGKLRISE 1742 G D + +GYG I + Sbjct: 845 GYGNDIYRYLSGYGHHIIDD 864 Score = 51.9 bits (124), Expect = 3e-08 Identities = 68/326 (20%), Positives = 115/326 (35%), Gaps = 57/326 (17%) Query: 770 NGVQQVEFSDGVTWTREQVISHLSVGAGSDYIVGTSAGEVLDGGGGNDYILGGGGADTYL 829 N +Q + ++ SHL G G D + ++ + G G+D + Y Sbjct: 595 NLIQHASVGNNQY-REIRIESHL--GDGDDKVFLSAGSANIYAGKGHDVV--------YY 643 Query: 830 FNAGYGLLTIN-QAEGAPGVISRLRFGAGIDARDITVKSDATGNLILLHANGTDKVVLEL 888 G LTI+ G + R G D+ V + + T+K + Sbjct: 644 DKTDTGYLTIDGTKATEAGNYTVTRVLGG----DVKVLQEVVKEQEVSVGKRTEKT--QY 697 Query: 889 QASRPKYGVGVVEFADGSTWTRQQLLQMSLTGSGAMDNIYGTTGADFIDGKGGTDYLKGR 948 ++ + G + ++ ++L+ G+ D +G+ D G G D ++G Sbjct: 698 RSYEFTHINGKNLTETDNLYSVEELI-----GTTRADKFFGSKFTDIFHGADGDDLIEGN 752 Query: 949 GGNDIFYYASGYGHVIIDEEDFARDAQNVLRFGAGISLTDLRFSVTSDGDVTITHGVPGD 1008 GND Y G ++ + + L G G + G+ + G D Sbjct: 753 DGNDRLYGDKG------NDTLSGGNGDDQLYGGDGNDKL-----IGVAGNNYLNGGDGDD 801 Query: 1009 EIVIRNMAGWDYSGVQRLEFANGESISKPDFLARTQYGSSGSDTLYGSRYVDSIDGLGGD 1068 E ++ + V G G+D LYGS D +DG GD Sbjct: 802 EFQVQGNSLA--KNVLF--------------------GGKGNDKLYGSEGADLLDGGEGD 839 Query: 1069 DTVYARGGGGDVFVFNQGYGHLTIDS 1094 D + G G D++ + GYGH ID Sbjct: 840 DLLKG-GYGNDIYRYLSGYGHHIIDD 864 Score = 50.0 bits (119), Expect = 1e-07 Identities = 28/75 (37%), Positives = 40/75 (53%), Gaps = 4/75 (5%) Query: 792 LSVGAGSDYIVGTSAGEVLDGGGGNDYILGGGGADTYLFNAGYGLLTINQAEGAPGVISR 851 L G G+D + G+ ++LDGG G+D + GG G D Y + +GYG I+ G + Sbjct: 815 LFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDDDGGKE---DK 871 Query: 852 LRFGAGIDARDITVK 866 L A ID RD+ K Sbjct: 872 LSL-ADIDFRDVAFK 885 Score = 47.7 bits (113), Expect = 6e-07 Identities = 42/171 (24%), Positives = 65/171 (38%), Gaps = 60/171 (35%) Query: 1824 GDDVLFGNSSAEYFDGLGGNDYIFGGGGGDTFIYKPGYGHLEIYENDYAGTNTLKFGTGI 1883 G+D L+G+ + G G+D ++GG G D I G+ N L G G Sbjct: 754 GNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLI--GVAGN-----------NYLNGGDGD 800 Query: 1884 DPGMMRIKGNSTSGIEIIDRISGGKVTLTNAMYGAGYGLQRVEFSDGTVWTASQLRSAVS 1943 D +++GNS + + + GGK Sbjct: 801 D--EFQVQGNSLAK----NVLFGGK----------------------------------- 819 Query: 1944 NAVATTEDDALFGTEVAEVFDGLGGGDYIQGGGGGDTFHYKVGYGRLEILE 1994 +D L+G+E A++ DG G D ++GG G D + Y GYG I + Sbjct: 820 ------GNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDD 864 Score = 35.7 bits (82), Expect = 0.002 Identities = 36/111 (32%), Positives = 47/111 (42%), Gaps = 17/111 (15%) Query: 2074 GNDVLFGSLLGPDRLDGLGGIDTVYGNGGNDTYVLGAGYGGQLTIFNGYMYGGADGKLEL 2133 GND L+G G D L G G D +YG GND + AG N Y+ GG DG E Sbjct: 754 GNDRLYGDK-GNDTLSGGNGDDQLYGGDGNDKLIGVAG--------NNYLNGG-DGDDEF 803 Query: 2134 DVSADRLWL-QRSGQDLKVSIMGTDASAVLRDWYKDDFRKLAAVQSGGEGS 2183 V + L G + G++ + +L DD K GG G+ Sbjct: 804 QVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLK------GGYGN 848
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.4 bits (146), Expect = 1e-13 Identities = 23/171 (13%), Positives = 47/171 (27%), Gaps = 3/171 (1%) Query: 1 MSLELSPRAIEIVEQTKLLLAAGGYHGFSYADVSERVHIGKASIHHHFPTKAELVLAVVA 60 E I++ L + G S ++++ + + +I+ HF K++L + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 RHRAQAREGLAGLDRHV-EDPLARLTAY-TEYWAQCIREGSLP-MCICAMLAAELPLIPP 117 + E DPL+ L + E + E Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 118 EIADEVRAYFGELSGWLASVLEKGVATGHFRLRDGVQAEAQAFMSTVHGAM 168 + R E + L+ + + A + G M Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLM 175
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.9 bits (75), Expect = 0.002 Identities = 15/60 (25%), Positives = 20/60 (33%) Query: 242 GWSLADIGLVLNVVGATAGLLVALAYGRLLKRWSRRGATLAAALLQAVGIGGLALPAMAW 301 W IG+ L G L A+ G + R R A + + G LA W Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 41.1 bits (96), Expect = 3e-07 Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 5/55 (9%) Query: 72 MEALFVDPDARGTGVGRAL----VEDALRRHP-GLSTDVNEQNAQAIGFYERLGF 121 +E + V D R GVG AL +E A H GL + + N A FY + F Sbjct: 92 IEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 96.4 bits (240), Expect = 5e-24 Identities = 99/357 (27%), Positives = 152/357 (42%), Gaps = 37/357 (10%) Query: 43 MPVIGPVVRGLRLAE---WHGGLVVTVAGVLWMLMARYWGGRSDRVGRRRVLLRAAAGYI 99 MPV+ ++R L + H G+++ + ++ A G SDR GRR VLL + AG Sbjct: 25 MPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAA 84 Query: 100 VSYLLLAIGLDLMLREPPPAWLALLALMALRALLGAFYAAMPTVSAARIADITAPEQRGA 159 V Y ++A P W+ L R + G A V+ A IADIT ++R Sbjct: 85 VDYAIMATA--------PFLWV----LYIGRIVAGITGATGA-VAGAYIADITDGDERAR 131 Query: 160 MMARLGAANGLGMVLGPAIGGLLVKDSLTLPLYIAAVLPLLGTLWLAAKLPSDAAHEPRV 219 + A G GMV GP +GGL+ S P + AA L L L LP E R Sbjct: 132 HFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRP 191 Query: 220 TPPLKLSDRRLRLPLAAMLLAMSAVITAQMIVGFYAMDALRQEP------------GPAA 267 L+ PLA+ A + A ++ F+ M + Q P A Sbjct: 192 LRREALN------PLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDA 245 Query: 268 RTAGWAMTTVGVMLILVQVGLAK--ARRMNAARCLAGGALLSGVGFLLVPVLGGAGGLVA 325 T G ++ G++ L Q + A R+ R L G + G G++L+ G + Sbjct: 246 TTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILL-AFATRGWMAF 304 Query: 326 CYAVMAAGMGLVFPSIQTLAANAVTADEQGIAAGSVIAVQGMAMVVAPLVCTLLYGV 382 V+ A G+ P++Q + + V + QG GS+ A+ + +V PL+ T +Y Sbjct: 305 PIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAA 361
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 104 bits (262), Expect = 6e-27 Identities = 78/364 (21%), Positives = 143/364 (39%), Gaps = 10/364 (2%) Query: 25 RNLAVCFAGSFSTIVAMTLLLPFLPLYVEELGVQGHAAIVQWSGVAYGATFFAAALVAPL 84 R L V + V + L++P LP + +L G+ AP+ Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVT--AHYGILLALYALMQFACAPV 62 Query: 85 WGRLGDRYGRKLMLVRASFGMAICMSLTGMVQSVWQLVLLRLLVGLAGGYASGSTILVAM 144 G L DR+GR+ +L+ + G A+ ++ +W L + R++ G+ G + + +A Sbjct: 63 LGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD 122 Query: 145 QAPKARSGWALGVLSAGIMAGNLVGPLIGGGLPPLIGIRATFLLAGGVIFLAFLATVFLI 204 G +SA G + GP++GG + A F A + L FL FL+ Sbjct: 123 ITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLL 181 Query: 205 KE-MPRPAKPARQEGKRRG-GWAQIPDKRPVAAMLATGMLLMFATMSIEPIITVYVGQLV 262 E +P R+E + VAA++A ++ + ++ Sbjct: 182 PESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRF 241 Query: 263 DDPARVTLVSGVVMSAAALGAILSASRLGRLADRVGHWTVIIGALAVAALLLVPQAFVTA 322 A T + + + L ++ A G +A R+G ++ + + AF T Sbjct: 242 HWDA--TTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATR 299 Query: 323 GWQLVALRFLMGLALGGL-LPCVTSVIRHNVPDGVGGNVLGMSISAQYAGQVAGPLLGGF 381 GW +A ++ LA GG+ +P + +++ V + G + G + + GPLL Sbjct: 300 GW--MAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTA 357 Query: 382 IGGH 385 I Sbjct: 358 IYAA 361
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 57.2 bits (138), Expect = 4e-11 Identities = 39/169 (23%), Positives = 70/169 (41%), Gaps = 4/169 (2%) Query: 5 WLVIALLALPQVAETILAPALPDLARHWRLDAAATQPVMGIFFVGFAAGVLLWGHLADTR 64 WL I + E +L +LPD+A + A+T V F + F+ G ++G L+D Sbjct: 18 WLCILSFFSV-LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQL 76 Query: 65 G-RRPAMLAGLALGLAGTLCALAAPAYPWLLAGRFLQALGLAACSVVTQTVLRDCLDGPR 123 G +R + + + + + L+ RF+Q G AA + V+ + Sbjct: 77 GIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKEN 136 Query: 124 LTHYFVTLGTVLAWSPAVGPLTGQALAD--GHGYGGVLAAIAVVVALLL 170 F +G+++A VGP G +A Y ++ I ++ L Sbjct: 137 RGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFL 185
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 96.0 bits (239), Expect = 1e-24 Identities = 93/371 (25%), Positives = 139/371 (37%), Gaps = 43/371 (11%) Query: 1 MKKTLLAAAMLTTFAGVAQAETSVTLYGVIDTGIGYNK-IKGNGYDGSKLGMINGI-QAG 58 MKK+L+A LT A A VTLYG I G+ ++ + NG + + GI G Sbjct: 1 MKKSLIA---LTLAALPVAAMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLG 57 Query: 59 SRWGLRGSEDLGDGLRAVFTLESGFDSGNGTRGQSGRLFGRQATIGLANDAWGTIEFGRQ 118 S+ G +G EDLG+GL+A++ +E G RQ+ IGL +G + GR Sbjct: 58 SKIGFKGQEDLGNGLKAIWQVEQK----ASIAGTDSGWGNRQSFIGLKGG-FGKLRVGRL 112 Query: 119 ATVGSNYLADIDPFYTSYTQSNLGLGFSAANTMRWDNMVMYRSPSMSGFQFAAGYSFNVD 178 +V + DI+P + S LG A V Y SP +G + Y+ N D Sbjct: 113 NSVLKDT-GDINP-WDS-KSDYLG-VNKIAEPEARLISVRYDSPEFAGLSGSVQYALN-D 167 Query: 179 DTNNDETHFRTNDNSRGITAGLRYVEGPVNVTLTYDQLNGSNRASIDHDATPRQYAVGLS 238 + NS AG Y G V + + + + Sbjct: 168 NAGRH--------NSESYHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIHRLVSG 219 Query: 239 YDLEVVKLAAAYGRTTDGWFVGQDLPAGTPFSDEFGTNRYVDGFKANAYMLGATMP-VGG 297 YD + + A+ + D + + N + AY G P V Sbjct: 220 YDNDAL-YASVAVQQQDA----------KLVEENYSHNSQTEVAATLAYRFGNVTPRVSY 268 Query: 298 ASSLFASWQHVSPSNDRLTGGDANMNVWSVGYTYDLSKRTNLYAYGSYGKDYAFIDGLKS 357 A S+ + + + VG YD SKRT+ + ++ S Sbjct: 269 AHGFKGSFDAT--------NYNNDYDQVVVGAEYDFSKRTSALVSAGWLQEGKGESKFVS 320 Query: 358 TAAGVGIRHVF 368 TA GVG+RH F Sbjct: 321 TAGGVGLRHKF 331
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 84.9 bits (210), Expect = 2e-20 Identities = 89/400 (22%), Positives = 135/400 (33%), Gaps = 71/400 (17%) Query: 1 MKKTLLAAAMLATFAGVAQAETSVTLYGIIDTGIGYNKVSGTEPGINLGTGKPQNVDVSG 60 MKK+L+A + A A VTLYG I G+ ++ N + Sbjct: 1 MKKSLIALTLAAL---PVAAMADVTLYGTIKAGVETSR------------SVAHNGAQAA 45 Query: 61 SRIGMINGVQSGSRWGLKGSEDLGDGLRAMFQLESGFDSGNGDTTLDRLFGRQATVGLAN 120 S V GS+ G KG EDLG+GL+A++Q+E D+ RQ+ +GL Sbjct: 46 SVETGTGIVDLGSKIGFKGQEDLGNGLKAIWQVEQKASIAGTDS---GWGNRQSFIGLKG 102 Query: 121 DAWGSVEFGRQATVGSNFLAEIDPFAASFTQANIGTGLSAANTMHWDNMIMYRSPWTDGF 180 +G + GR +V L + ++++ A + Y SP G Sbjct: 103 G-FGKLRVGRLNSV----LKDTGDINPWDSKSDYLGVNKIAEPEARLISVRYDSPEFAGL 157 Query: 181 QFALGYSFNVDTDDGNQTGFRTADNARGITAGLRYVQGPLNVSLTYDQLNSSNKAYATGK 240 ++ Y+ N + G N+ AG Y G V Sbjct: 158 SGSVQYALN------DNAGR---HNSESYHAGFNYKNGGFFVQYGGAYKRH--------- 199 Query: 241 NGRPVFDDAGNRVALDNNITPRQYAVAVSYDLEVLKLAAAYGRTTDGWFVGQDLPEGSAS 300 V ++ + + + YD + L A+ + D V ++ S + Sbjct: 200 ------HQVQENVNIEKY---QIHRLVSGYDNDAL-YASVAVQQQDAKLVEENYSHNSQT 249 Query: 301 NHFGTYRYAEGF--KANSYMLGATLRLDGASNLFGSWQHVSPSNDLLTGDDARMNIWSVG 358 T Y G SY G D + + VG Sbjct: 250 EVAATLAYRFGNVTPRVSYAHGFKGSFDAT------------------NYNNDYDQVVVG 291 Query: 359 YTYDLSKRTSLYAYGSYGKNYAFIDGLKSTAGGVGMRHLF 398 YD SKRTS + + STAGGVG+RH F Sbjct: 292 AEYDFSKRTSALVSAGWLQEGKGESKFVSTAGGVGLRHKF 331
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 93.7 bits (233), Expect = 1e-23 Identities = 92/394 (23%), Positives = 140/394 (35%), Gaps = 68/394 (17%) Query: 1 MKKKLLAAAVLTALASVAQAATSVTLYGLIDTGIGYNRITGDANGADYSGSRIGMINGVQ 60 MKK L+A LT A A VTLYG I G+ +R S I V Sbjct: 1 MKKSLIA---LTLAALPVAAMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGI--VD 55 Query: 61 AGSRWGLRGTEDLGDGLRAVFRLENGFNSADGSRLQQGRMFGRQATIGLADDAWGSVDFG 120 GS+ G +G EDLG+GL+A++++E + A RQ+ IGL +G + G Sbjct: 56 LGSKIGFKGQEDLGNGLKAIWQVEQKASIAGT----DSGWGNRQSFIGLKGG-FGKLRVG 110 Query: 121 RQTSVGSLLLADINPFRTTFTQASIGTTFSAANTMRWDNMVLYRSPWTDGFQFAVGYSFN 180 R SV DINP+ + + + V Y SP G +V Y+ N Sbjct: 111 RLNSV-LKDTGDINPWDSKSDYLGVNKIAEPEARL---ISVRYDSPEFAGLSGSVQYALN 166 Query: 181 VDGTDEEQSGFRTADNARGITAGLRYANGPLNIVLTFDQLNGSNLASVDAFGDPVDHNAT 240 + +G N+ AG Y NG + + + + + Sbjct: 167 DN------AGR---HNSESYHAGFNYKNGGFFVQYGGAYKRHHQVQE-NVNIE--KYQI- 213 Query: 241 PRQYAVGMSYDLEVVKLAAAYGRTTDGWFVGQDLPAGVRGKQAAGAMRRSEKLFGTNRYE 300 + + YD + + A+ + + E+ + N Sbjct: 214 ---HRLVSGYDNDAL-YASVAVQQ--------------------QDAKLVEENYSHNSQT 249 Query: 301 EGFRANSYMLGATVP-----LGGGGSVFGAWQHASASSDALTGDDANMDIWSLGYTYDLS 355 E +Y G P G GS + + D +G YD S Sbjct: 250 EVAATLAYRFGNVTPRVSYAHGFKGSFDAT------------NYNNDYDQVVVGAEYDFS 297 Query: 356 KRTNLYVYGSYGKNYAFIEGLKSTAGGVGIQHRF 389 KRT+ V + + STAGGVG++H+F Sbjct: 298 KRTSALVSAGWLQEGKGESKFVSTAGGVGLRHKF 331
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 26.7 bits (59), Expect = 0.038 Identities = 13/61 (21%), Positives = 24/61 (39%), Gaps = 11/61 (18%) Query: 65 LAFAVVQIVVHIIYFLHMDTKSESGWNMLALIFTLVLVVITLSGSIWIMYHLN--SNMMP 122 L A++ + + + FL NM A + + V + L G+ I+ N + Sbjct: 344 LFEAIMLVFLVMYLFLQ---------NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLT 394 Query: 123 M 123 M Sbjct: 395 M 395
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 108 bits (270), Expect = 2e-30 Identities = 71/254 (27%), Positives = 111/254 (43%), Gaps = 13/254 (5%) Query: 7 GKRVLITGASKGIGLACATAFAREGAEPILAARDDAALQAASQAILAQTGRQPRTVAVDL 66 GK ITGA++GIG A A A +GA I A + + L R D+ Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAH-IAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 67 AQPGA----AARVLERTGAIDILVNNAGAVPGGALDQVQDERWRAGWDLKVHGYIDLARH 122 A AR+ G IDILVN AG + G + + DE W A + + G + +R Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 123 YYPLMRAAGAGVIANIIGMAGSAPRADYICGAAANASLIAFTRALGGDGPRHGVRVFGVN 182 M +G I + PR A++ A+ + FT+ LG + + +R V+ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 183 PSRTRTDRVLTLARQRAQARWGDESRWQETLND----LPFGRLMEPEEVADMVVFGASPR 238 P T TD + G E + +L +P +L +P ++AD V+F S + Sbjct: 187 PGSTETD----MQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 239 AGYLSGTVIDLDGG 252 AG+++ + +DGG Sbjct: 243 AGHITMHNLCVDGG 256
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 37.2 bits (86), Expect = 1e-05 Identities = 19/90 (21%), Positives = 37/90 (41%), Gaps = 5/90 (5%) Query: 66 ALLVAWQDGRIAGSVQLDCDTPPNQPHRAEIRKLMVHPDFRRQGIARALMRAAEAAAVVA 125 A + + + G +++ N A I + V D+R++G+ AL+ A A Sbjct: 66 AAFLYYLENNCIGRIKIR----SNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKEN 121 Query: 126 GRSLITLDTRTGD-NAEPLYASLGYHTVGV 154 + L+T+ + +A YA + V Sbjct: 122 HFCGLMLETQDINISACHFYAKHHFIIGAV 151
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 95.1 bits (236), Expect = 2e-25 Identities = 55/184 (29%), Positives = 87/184 (47%), Gaps = 3/184 (1%) Query: 5 KIWFVTGASGGLGLALVRMLLDQGHKVAATSRDVDALMDAVGA-KLEGRFL-PLEVNLAD 62 KI F+TGA+ G+G A+ R L QG +AA + + L V + K E R ++ D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 63 EGNVRRAVDTTVAAFGRIDVVVNNAGHGLAGALETLSDAELRDSFDINVFGVLNVVRAVM 122 + G ID++VN AG G + +LSD E +F +N GV N R+V Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 123 PRLRAQRGGHVFNISSILGFDGGSAGWGAYSAAKFAVSGLSETLALEAAPHGVRVSLVYP 182 + +R G + + S AY+++K A ++ L LE A + +R ++V P Sbjct: 129 KYMMDRRSGSIVTVGSNPA-GVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 183 GAMR 186 G+ Sbjct: 188 GSTE 191
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.4 bits (240), Expect = 8e-26 Identities = 28/99 (28%), Positives = 52/99 (52%) Query: 9 LLIDDDELYVRTLQRSLSRRGLETRTATGIAEALRVAEEIRPAFALVDLRLGEDSGLTLI 68 L+ DDD L ++LSR G + R + A R + D+ + +++ L+ Sbjct: 7 LVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLL 66 Query: 69 RPLRALRADMRILLVTGYASVATAVEAIKRGADDYLPKP 107 ++ R D+ +L+++ + TA++A ++GA DYLPKP Sbjct: 67 PRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKP 105 Score = 50.2 bits (120), Expect = 9e-10 Identities = 16/40 (40%), Positives = 25/40 (62%) Query: 134 LHRLEWEHIHQALHETGGNVSAAARLLGMHRRSLQRKLAK 173 L +E+ I AL T GN AA LLG++R +L++K+ + Sbjct: 433 LAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.5 bits (235), Expect = 1e-24 Identities = 34/119 (28%), Positives = 59/119 (49%) Query: 2 RILVVEDEPTLAAQLAEALRLAGYTVDTAADGADAHYMGEVETYDVVVLDLGLPVMDGLT 61 ILV +D+ + L +AL AGY V ++ A D+VV D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLKQWRAAGRGMPVLILTARSNWHEKVAGIDAGADDYLTKPFHMEELLARVRALLRRYS 120 +L + + A +PVL+++A++ + + + GA DYL KPF + EL+ + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123
>PF06580#Sensor histidine kinase Length = 349 Score = 32.9 bits (75), Expect = 0.002 Identities = 41/219 (18%), Positives = 73/219 (33%), Gaps = 50/219 (22%) Query: 271 ATREEGAFARLVRE-QVAMAQRQIDHH-----LARARAAAASGTAGGRTPLRAPLQALLR 324 A ++ A + +E Q+ + QI+ H L RA R L + L L+R Sbjct: 147 AEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTS-LSELMR 205 Query: 325 ------------VMQRLYAARE-LQLEMDEFADRL--EFRGEEQDLQEMVGNLL-----D 364 + L LQL +F DRL E + + V +L + Sbjct: 206 YSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVE 265 Query: 365 NACKWAAR------RVRIGAQATAPDRLSIVIDDDGPGISEDERERIFERGVRMDEQRPG 418 N K ++ + +++ +++ G ++ +E Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDN-GTVTLEVENTGSLALKNTKE--------------S 310 Query: 419 SGLGLDIVRD-LAGTYGGEVSAG-PSPLGGLRVTLTLPA 455 +G GL VR+ L YG E G + + +P Sbjct: 311 TGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIPG 349
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 56.0 bits (135), Expect = 1e-10 Identities = 81/412 (19%), Positives = 144/412 (34%), Gaps = 38/412 (9%) Query: 21 LFVCWLAILFEGYDVGVMGAVLPALADD--KSWNLSSIELGMLGSYALAGMFVGSFAVGT 78 L V + + +G++ VLP L D S ++++ +L YAL G Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVL-GA 65 Query: 79 LSDLLGRRRMLLACVTLFSLTMIGAAWAPTPTWFAAFRFIGGLGLGGVIPVAAALTIEYS 138 LSD GRR +LL + ++ A AP R + G+ G VA A + + Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADIT 124 Query: 139 PPAKRGFNYGVMYSGYSLGILCSAAVAMAVLQHWGWRAVILVGAAPLLLVPVLARLLPES 198 +R ++G M + + G++ + ++ + A AA L + Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLG-GLMGGFSPHAPFFAAAALNGLNFLTG------ 177 Query: 199 LEYLLAKGDEAGARAMAQRLGIASLESFRPREVTGEKTTWRDVMAAVFAPRHLRATLCFW 258 L G R +R + L SFR W M + Sbjct: 178 --CFLLPESHKGERRPLRREALNPLASFR----------WARGMT----------VVAAL 215 Query: 259 GALFLGMMLVYGLNTWLPQIMRKNGYDLGSS---ISFLLVFSLASAIGGLVLGQFADKSE 315 A+F M LV + L I ++ + ++ IS L S ++ G A + Sbjct: 216 MAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLG 275 Query: 316 PRRIVALSYLVGAIGIYCLTYNNPLAVNYLWVALAGIGSISSSLILTGYLAGYYPAHARG 375 RR + L + G L + + + + L G I L L+ +G Sbjct: 276 ERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMP-ALQAMLSRQVDEERQG 334 Query: 376 AATGWALSFARIGAMSGPIVGGYLAGLQLPLAWNFMAFSCAAVLAAVFVILI 427 G + + ++ GP++ + + WN A+ A L + + + Sbjct: 335 QLQGSLAALTSLTSIVGPLLFTAIYAASIT-TWNGWAWIAGAALYLLCLPAL 385
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 86.6 bits (214), Expect = 2e-22 Identities = 64/250 (25%), Positives = 109/250 (43%), Gaps = 13/250 (5%) Query: 2 IKDKVIIITGASSGIGEATAKLLASKGARVVLGARRADNLKRIADEIKQHGGQAVYRELD 61 I+ K+ ITGA+ GIGEA A+ LAS+GA + + L+++ +K A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 62 VAKQADNDAIVKLAKEKFGRVDAIFLNAGLMPTSPLSALKTDDWHQMVDVNVKGVLNGVA 121 V A D I + + G +D + AG++ + +L ++W VN GV N Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 122 AVLPEFLAQKSGHVIATSSVAGLKAYPGSAVYGGTKWFVRDFMEVLRIESAMEGTNIRTA 181 +V + ++SG ++ S A Y +K F + L +E A NIR Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA--EYNIRCN 183 Query: 182 TIYPAAINTELLATI--SDKQSLDQMRGLYDTY--GI------SPDRIANVVAF-AIDQP 230 + P + T++ ++ + + ++G +T+ GI P IA+ V F Q Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 231 DDTTINEFTV 240 T++ V Sbjct: 244 GHITMHNLCV 253
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 35.6 bits (82), Expect = 2e-06 Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 1/45 (2%) Query: 11 HRAQATLVAARLAQGVGAAATVPASMALIRQAYPDPLRRGHAVAL 55 H + L+ AR QG GAAA PA + ++ Y RG A L Sbjct: 100 HSFFSLLIMARFIQGAGAAA-FPALVMVVVARYIPKENRGKAFGL 143
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 28.3 bits (63), Expect = 0.028 Identities = 12/65 (18%), Positives = 25/65 (38%), Gaps = 3/65 (4%) Query: 10 GPVIGGWLVSLDWRWVFYLNLPVGLLTVAFLART--PVSPRRTAPFDMAGQAMATLAMGA 67 GP IGG +++ W + L +P+ + R FD+ G + ++ + Sbjct: 155 GPAIGG-MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVF 213 Query: 68 LIYGA 72 + Sbjct: 214 FMLFT 218
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 358 bits (920), Expect = e-120 Identities = 132/365 (36%), Positives = 202/365 (55%), Gaps = 25/365 (6%) Query: 206 ISRLRKEVNFYRRELSSMDQPNRGLDAIIGDSEPVARLKEQIVKIAPLDVPVLLLGESGV 265 I + + + +R S ++ ++ ++G S + + + ++ D+ +++ GESG Sbjct: 112 IGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGT 171 Query: 266 GKDVVAHAIHMLGPRASDPMVVINAAALPVSLVESELFGYESGAFTGADRKGRPGKFEQA 325 GK++VA A+H G R + P V IN AA+P L+ESELFG+E GAFTGA + G+FEQA Sbjct: 172 GKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTR-STGRFEQA 230 Query: 326 DGGSLFLDEIGDMPLEVQVKLLRTLQDGTFQRVGGESLHRSNFRLISASNRDFHRMLDSG 385 +GG+LFLDEIGDMP++ Q +LLR LQ G + VGG + RS+ R+++A+N+D + ++ G Sbjct: 231 EGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQG 290 Query: 386 AFRLDLFYRISAVTLRLPSLRERLEDIPVLAGTFLKQFADRHGLPVKEIEPAALRFLQSL 445 FR DL+YR++ V LRLP LR+R EDIP L F++Q + GL VK + AL +++ Sbjct: 291 LFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMKAH 349 Query: 446 PWPGNVRQLQHAIERAAIFCDGDAIRVADFE-----------------------MAGEAR 482 PWPGNVR+L++ + R D I E ++ Sbjct: 350 PWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVE 409 Query: 483 GAYHLDTARVATAAPRDGSMKEVKDRMEADLIVEYLQRFHGNKKKVAEALGISRSYLYKR 542 A A P G V ME LI+ L GN+ K A+ LG++R+ L K+ Sbjct: 410 ENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKK 469 Query: 543 LAEIN 547 + E+ Sbjct: 470 IRELG 474
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 103 bits (257), Expect = 1e-28 Identities = 71/249 (28%), Positives = 120/249 (48%), Gaps = 16/249 (6%) Query: 3 ENIKDKVVVITGASSGLGEATARLLAQNGAKLILAARRLDRLQALAHQLGLGA--DATVK 60 + I+ K+ ITGA+ G+GEA AR LA GA + ++L+ + L A Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 61 ADVTDRSQVEALIAHAVKKHGRVDVLLNNAGLMPSSMLENLHIDEWDRMIDVNIKGVLYG 120 ADV D + ++ + A ++ G +D+L+N AG++ ++ +L +EW+ VN GV Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 121 IAAVLPVMQRQKSGHIINVSSVAGHKVGPGGTVYAATKHAVRVISEGLRQEVKPYNIRTT 180 +V M ++SG I+ V S YA++K A + ++ L E+ YNIR Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 181 IISPGAVATNL-----IDTITDPAIAANMKKTYEKAIPAESFARVVAFAMSQPEDVDVNE 235 I+SPG+ T++ D + +T++ IP + A+ P D+ + Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAK--------PSDI-ADA 234 Query: 236 VLFRPTSQA 244 VLF + QA Sbjct: 235 VLFLVSGQA 243
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 134 bits (339), Expect = 1e-40 Identities = 83/253 (32%), Positives = 119/253 (47%), Gaps = 8/253 (3%) Query: 6 EGKVALVTGASAGIGLATAKAFAEAGARVALAAHDKYKLEEAANTLSAAGHEVLAVTCDV 65 EGK+A +TGA+ GIG A A+ A GA +A ++ KLE+ ++L A A DV Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 66 ADEAQVKAMVERTIKKFGRLDAAYNNAGVQSPVAETADADGKEFDHVQAVNLRGVWSCMK 125 D A + + R ++ G +D N AGV P +E++ +VN GV++ + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRP-GLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 126 YELIQMRDQGSGAIVNCSSMGGLIGIAGRGAYHASKHGVIGLTKSAALEYAARGIRINAV 185 M D+ SG+IV S + AY +SK + TK LE A IR N V Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 186 CPGIIETPMVSRMLKREPEAMDILMKDQ-------PIGRLGRPEEIASAVLWLCSPGASF 238 PG ET M + E A ++ P+ +L +P +IA AVL+L S A Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 239 VIGQALAVDGGYT 251 + L VDGG T Sbjct: 246 ITMHNLCVDGGAT 258
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.0 bits (65), Expect = 0.034 Identities = 19/146 (13%), Positives = 43/146 (29%), Gaps = 26/146 (17%) Query: 217 DAEAARADAEKARADQAEQSIEQARQDAKGAALARVKLEAVATEHKVAFKADSTDRALRE 276 A A AD K ++ + +EQ R ++ KL + + + + E Sbjct: 128 TALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPE------LKLPDEPYFQNVSE 181 Query: 277 GVIKAVRGDSADLADKSDGYIEAAFDLAVGEAKSRQDAVETQRRELAG---------GEP 327 + + I+ F + ++ ++ +R E Sbjct: 182 EEVLRLT-----------SLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLS 230 Query: 328 SAARQQRSDSAPPPKSASAARSAYLA 353 + + D + + A+ A L Sbjct: 231 RVEKSRLDDFSSLLHKQAIAKHAVLE 256
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 97.0 bits (241), Expect = 1e-22 Identities = 46/192 (23%), Positives = 69/192 (35%), Gaps = 21/192 (10%) Query: 2003 FLEMRDGHAPTNGDLYQYIKDHHADFNLADDPRGGDDTIHGGTGDDIIYGQGGNDTLYGD 2062 F D ++ DF+ + G GN ++ Sbjct: 281 FYTATDSSKALIFSVWDAGGTDTFDFSGYS---NNQRINLNEGSFSDVGGLKGNVSIAHG 337 Query: 2063 DGNDIIYGGAGDDKLYGGEGNDVLHGGSGNDTLEGGNGNDLLIGGKGDDTLIGGAGSDTF 2122 + GG+G+D L G +++L GG+GND L GG G D L GG G DT + G+G D+ Sbjct: 338 VTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDST 397 Query: 2123 KWELGDQGTTAKPAVDTIKDFSLDKPADGGDVLDLKDLLVGEKDGTLTQYLNFHKEGNNT 2182 A D I DF G D +DL E + Q F +G Sbjct: 398 -----------VAAYDWIADFQK-----GIDKIDLSAFR-NEGQLSFVQ-DQFTGKGQEV 439 Query: 2183 VIDVNTQGKLGT 2194 ++ + + Sbjct: 440 MLQWDAANSITN 451
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 54.5 bits (131), Expect = 8e-11 Identities = 35/164 (21%), Positives = 65/164 (39%), Gaps = 11/164 (6%) Query: 39 IRVAILDDHPVVALGVGAYLDSRPGFRVIHQETSARRLLEKLATSPCDVALIDFYLPQEP 98 + + DD + + L SR G+ V ++A L +A D+ + D +P E Sbjct: 4 ATILVADDDAAIRTVLNQAL-SRAGYDV-RITSNAATLWRWIAAGDGDLVVTDVVMPDE- 60 Query: 99 WDGVNYLRRLRRYHPSMAIITFSAGNRQETQYAAFRAGANGYLAKQWGMILLPEMIHGVL 158 + + L R+++ P + ++ SA N T A GA YL K + L E+I + Sbjct: 61 -NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFD---LTELIG--I 114 Query: 159 SRKDPFLSVQEGKIRPLSPRPPHALLTTSE--VEVLRHISQGMS 200 + + + L+ S E+ R +++ M Sbjct: 115 IGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQ 158
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 570 bits (1471), Expect = 0.0 Identities = 230/555 (41%), Positives = 329/555 (59%), Gaps = 7/555 (1%) Query: 3 GKGVARGYAIGRAVVMGAAALEVAHYRIAPEDVPAESSRLTEALASAQQELRQLADTLPA 62 G + G AI +A + +++ I DV E +LT AL +++ELR + D A Sbjct: 7 GIAASSGVAIAKAFIHLEPNVDIEKTSI--TDVSTEIEKLTAALEKSKEELRAIKDQTEA 64 Query: 63 DAPRELGAMLNVHSLLLGDPLLAEQTLALIAERHYNAEWALTTQGQILGQQFDAMEDEYL 122 + + H L+L DP L + I NAE+AL + F++M++EY+ Sbjct: 65 SMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEYM 124 Query: 123 RERGADVRQVIERVLHVLSGTSAILPDMSHMGGDEALVVVAHDISPADMLRLRGGRFAAF 182 +ER AD+R V +RVL L G ++ + E V++A D++P+D +L F Sbjct: 125 KERAADIRDVSKRVLGHLIGVE--TGSLATI--AEETVIIAEDLTPSDTAQLNKQFVKGF 180 Query: 183 VTDLGGPTSHTAIVARSMGVPAVVAMGNVRELVRDGDMLIIDGAAGAVVVNPSERILQEY 242 TD+GG TSH+AI++RS+ +PAVV V E ++ GDM+I+DG G V+VNP+E ++ Y Sbjct: 181 ATDIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAY 240 Query: 243 RRRQAAYADERAELGLLRDEPSVTLDGIDIVLHANIELPEEAALALASGAHGIGLFRSEF 302 ++AA+ ++ E L EPS T DG + L ANI P++ LA+G GIGL+R+EF Sbjct: 241 EEKRAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEF 300 Query: 303 LFMGRPDLPGEEEQYEAYASVVKVMAGRPVTIRTLDIGSDKTLDG-EATVATNPALGQRA 361 L+M R LP EEEQ+EAY VV+ M G+PV IRTLDIG DK L + NP LG RA Sbjct: 301 LYMDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFRA 360 Query: 362 IRYCLARPEMFATQLRAILRASAHGPVRLLIPMIAHMHEVVATRAAIESARRELDARGQA 421 IR CL + ++F TQLRA+LRAS +G ++++ PMIA + E+ +A ++ + +L + G Sbjct: 361 IRLCLEKQDIFRTQLRALLRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVD 420 Query: 422 YAAHMEVGAMVEVPAIAIAIEPFAQALDFLSIGTNDLIQYTLAIDRGDHDVASLYDPLHP 481 + +EVG MVE+P+ A+A FA+ +DF SIGTNDLIQYT+A DR + V+ LY P HP Sbjct: 421 VSDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHP 480 Query: 482 AVLRLVAHTINAGERAGKPVAVCGEMAGDSRMTRLLLGLGLTEFSMHPQQLLDVKREVRR 541 A+LRLV I A GK V +CGEMAGD LLLGLGL EFSM +L + ++ + Sbjct: 481 AILRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLK 540 Query: 542 AHTNALRVKVASALN 556 L+ AL Sbjct: 541 LSKEELKPFAQKALM 555
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.7 bits (77), Expect = 0.002 Identities = 33/145 (22%), Positives = 48/145 (33%), Gaps = 13/145 (8%) Query: 220 ARRALEVAAAGGHSLLMVGPPGAGKSMLAARLPGLLPPLARTQALEVAAIAALAGAPEAR 279 R L +L++ G G GK ++A L R +AA+ P Sbjct: 149 IYRVLARLMQTDLTLMITGESGTGKELVARALHDYGK--RRNGPFVAINMAAI---PRDL 203 Query: 280 MGTPPFRAPHHSASPFALVGGGGRPRPGEISLAHHGVLFLDELPEFSRRALEALREPLET 339 + + F H F G G A G LFLDE+ + A L L+ Sbjct: 204 IESELF---GHEKGAFT---GAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQ 257 Query: 340 GRVVIARALHTAQFPARFQLVAAMN 364 G + ++VAA N Sbjct: 258 GE--YTTVGGRTPIRSDVRIVAATN 280
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 117 bits (296), Expect = 2e-38 Identities = 37/89 (41%), Positives = 53/89 (59%) Query: 9 TKAELAELLFERVGLNKREAKDIVDTFFEEIRDALARGDSVKLSGFGNFQVRDKPPRPGR 68 K +L + E L K+++ VD F + LA+G+ V+L GFGNF+VR++ R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 69 NPKTGETIPIAARRVVTFHASQKLKSVVE 97 NP+TGE I I A +V F A + LK V+ Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.6 bits (71), Expect = 0.001 Identities = 25/128 (19%), Positives = 49/128 (38%), Gaps = 12/128 (9%) Query: 4 ATLKTRLSDAVKDAMRAKATERLATLRFLLAAVKQKEVD------ERRDLSDAEITAIIE 57 T++ DA + + + + A + A + EV + ++ + TA +E Sbjct: 1049 KTVEKNEQDATETTAQNREVAKEAKSN-VKANTQTNEVAQSGSETKETQTTETKETATVE 1107 Query: 58 KQVKQRRESIAAFEQAGRT--ETAEQEKAELVVLQEFLPQAATPEEVAAAIDAALAEVAA 115 K+ K + E+ E T + +QE++E V Q + A + I ++ Sbjct: 1108 KEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQ---AEPARENDPTVNIKEPQSQTNT 1164 Query: 116 QGVTGAPA 123 T PA Sbjct: 1165 TADTEQPA 1172
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 102 bits (254), Expect = 2e-28 Identities = 67/248 (27%), Positives = 110/248 (44%), Gaps = 14/248 (5%) Query: 6 ILVTGSSRGIGRAIALALADAGHDLVLHCRQQRAQAEAVQAEIAARGRQARVLQFDVADR 65 +TG+++GIG A+A LA G + + V + A R A DV D Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSL-KAEARHAEAFPADVRDS 69 Query: 66 AQCAAVLQADVDAHGAYYGVVLNAGLTRDGAFPALTGDDWDQVLRTNLDGFYNVLGPLAM 125 A + G +V AG+ R G +L+ ++W+ N G +N ++ Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 126 PMIRRRAPGRVVCMASVSGLIGNRGQVNYSASKAGLIGAAKALAVELAKRQITVNCVAPG 185 M+ RR+ G +V + S + Y++SKA + K L +ELA+ I N V+PG Sbjct: 130 YMMDRRS-GSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 186 LIDTDMI-------DAHVPV-----EEILKAVPAQRMGRPEEVAATVAFLMSPGAAYITR 233 +TDM + V E +P +++ +P ++A V FL+S A +IT Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248 Query: 234 QVIAVNGG 241 + V+GG Sbjct: 249 HNLCVDGG 256
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 40.6 bits (95), Expect = 3e-05 Identities = 29/142 (20%), Positives = 48/142 (33%), Gaps = 26/142 (18%) Query: 648 LVAAALLCLTL------GRAAAWRILAVPLAATACSLAALGYLGQPLTLFSLFGLLLVSA 701 A L+ L + RA +AVP+ + A L G + ++FG++L Sbjct: 345 FEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLG-TFAILAAFGYSINTLTMFGMVLAIG 403 Query: 702 IGVDYAIFMFERVAGAAA-------------------SLVGIMLGAITTLLSFGLLAVSR 742 + VD AI + E V +LVGI + + S Sbjct: 404 LLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGST 463 Query: 743 TPAIANFGLAVALGVGFSLLWA 764 F + + + S+L A Sbjct: 464 GAIYRQFSITIVSAMALSVLVA 485 Score = 30.6 bits (69), Expect = 0.031 Identities = 32/134 (23%), Positives = 56/134 (41%), Gaps = 18/134 (13%) Query: 257 IAMAGIVLVLLLALRRWLALLALVP-VAVGL-LAGTVACVAVFG-SIHALTLVIGASLIG 313 A+ + LV+ L L+ A L+P +AV + L GT A +A FG SI+ LT+ IG Sbjct: 346 EAIMLVFLVMYLFLQNMRA--TLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIG 403 Query: 314 VAVDFPM------HWLGKSYGMPDWRA-WPALRRVLPGLTISLAASLVGYVALAFTP--- 363 + VD + + +P A ++ ++ L ++ +AF Sbjct: 404 LLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGST 463 Query: 364 ---FPALTQTAVFS 374 + + T V + Sbjct: 464 GAIYRQFSITIVSA 477
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.4 bits (79), Expect = 8e-04 Identities = 84/377 (22%), Positives = 116/377 (30%), Gaps = 67/377 (17%) Query: 53 GLLADRWGDRPVLLGGLGATAAALAWMSLFAAPAHGVAPALWLLALGLLLVGVMGGSVNG 112 G L+DR+G RPVLL L A A M AP LW+L +G ++ G+ G + G Sbjct: 64 GALSDRFGRRPVLLVSLAGAAVDYAIM--------ATAPFLWVLYIGRIVAGITGAT--G 113 Query: 113 ASGRAVMA----------WFDEGERGLAMSIRQTAVPLGGGLGALVLPWLASRAGFGAVF 162 A A +A F G A P+ GGL P + A Sbjct: 114 AVAGAYIADITDGDERARHF--GFMSACFGFGMVAGPVLGGLMGGFSP--HAPFFAAAAL 169 Query: 163 GLLAGLCAGAALLTLGWLREPDRAHPATAAGSTAASHAGDNTPTTSPRSRAATHTPIAAA 222 L L L E H G+ P A Sbjct: 170 NGL------NFLTGCFLLPES---------------HKGERRPLRREALNPLASFRWARG 208 Query: 223 SSPLRDARVWRAAVAIGLLCCPQFAVLTFATVFLHDFSGAGIATLTAVMVAVQLGAMVAR 282 + + AV + Q + F ++ L ++ Sbjct: 209 MTVV----AALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQA 264 Query: 283 IAGGRWTDRHGNRRAYLRGCVWLGCVL-FVALAAAAWLQGAVPGNRAALLAVPVLLAAAG 341 + G R G RRA + G + G +A A W+ + VLLA+ G Sbjct: 265 MITGPVAARLGERRALMLGMIADGTGYILLAFATRGWM----------AFPIMVLLASGG 314 Query: 342 ICASAWHGVAYTELVTLAGAARAGTALGLANTCGYLGLFLTPLALPRLVAA--ASWP-LA 398 I A + L R G G L + PL + AA +W A Sbjct: 315 IGMPALQAM----LSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWA 370 Query: 399 WLAAGGAMLAILPLLPR 415 W+A L LP L R Sbjct: 371 WIAGAALYLLCLPALRR 387
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 37.2 bits (86), Expect = 1e-04 Identities = 32/180 (17%), Positives = 64/180 (35%), Gaps = 3/180 (1%) Query: 67 LVLLLAVACALSVANVYYAQPLLDAMGREFRLDEGAVGIVVTATQLGCALALVLVVPLGD 126 +++ L + SV N L + +F + V TA L ++ + L D Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 127 LLDRRRLMLAQLGLLVLA-LAAVALASAAPWLLAGMLALGLLGTAMTQGLLALSAALAAP 185 L +RL+L + + + S L+ G A ++ + A Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 186 GERGRVVGAVQGGVVIGLLLARTLAGAVADLWGWRAVYLVSAGLAALLALALARWLPRRA 245 RG+ G + V +G + + G +A W YL+ + ++ + L ++ Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKE 192
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 107 bits (268), Expect = 9e-30 Identities = 75/257 (29%), Positives = 112/257 (43%), Gaps = 18/257 (7%) Query: 24 DGKTVMVTGGGSGLGRCTAHELASLGARLALVGRKPEKLEAARDELARI--YPEAADRIT 81 +GK +TG G+G A LAS GA +A V PEKLE L + EA Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEA----- 61 Query: 82 LHACDIRGETGVRGAVADALAAHGAIDGLFNCAGGQFPAPLEQISFNGWNAVVQNNLHGT 141 D+R + A G ID L N AG P + +S W A N G Sbjct: 62 -FPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 142 FLMAREVYTQHMRQHGGAIVNMLADIWGGMP--GMGHSGAARAGVWNLTETAACEWAHAG 199 F +R V M + G+IV + ++ G+P M +++A T+ E A Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNP-AGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 200 VRVNAVAPGWIASSGMDS-YDEDYRA--VLRGLAAK----VPLQRFGTEAELAAAVVFLL 252 +R N V+PG + S + ++ A V++G +PL++ +++A AV+FL+ Sbjct: 180 IRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 253 SPAAAFINGSVIRVDGG 269 S A I + VDGG Sbjct: 240 SGQAGHITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 76.6 bits (188), Expect = 4e-19 Identities = 36/205 (17%), Positives = 67/205 (32%), Gaps = 13/205 (6%) Query: 13 PASAKSEQRIRDILRVARQVFSEAGFQAATTTEIAQRLGVSEGTVFTYFGGKRELCVRVI 72 ++++ + IL VA ++FS+ G + + EIA+ GV+ G ++ +F K +L + Sbjct: 4 KTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW 63 Query: 73 SDWYDEIIAKVEDYLPHMQGA---------RAQLHYLVHAHLRHLLAEGTGLCAFILSEG 123 I +Y G L V R LL E F E Sbjct: 64 ELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLME----IIFHKCEF 119 Query: 124 RARNDDFGEIYAGLQRRYTAPLMRILAQGQADGHVRQDMPLRLLRSAIYGPMEHVLWDAI 183 + L + + L + D+ R + G + ++ + + Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL 179 Query: 184 LRGTRVDVAATADQLVDFLWQALQP 208 D+ A V L + Sbjct: 180 FAPQSFDLKKEARDYVAILLEMYLL 204
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 108 bits (271), Expect = 1e-30 Identities = 74/254 (29%), Positives = 111/254 (43%), Gaps = 12/254 (4%) Query: 2 KGLADKTAIVTGGATLIGAGVVAALRAGGVRVAIFDIDAEGAARVAASDPDGIR---AWP 58 KG+ K A +TG A IG V L + G +A D + E +V +S R A+P Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 59 LDITDDTQLARAVAEVAAHFGRIDYLVNLAATYLDDGAAS--GRADWLRALDINVVSAVM 116 D+ D + A + G ID LVN A L G +W +N Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVN-VAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 117 AARAVHPHLVAAGGGAIVNFTSISSRVAQTGRWLYPVSKAALLQVTRSLAMDYAGDRIRV 176 A+R+V +++ G+IV S + V +T Y SKAA + T+ L ++ A IR Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 177 NSVSPGWTWSRVMDELTHGDRAKTDRVAAD---FHL---LGRAGDPAEVAEVVAFLLSDH 230 N VSPG T + + L + + F L + P+++A+ V FL+S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 231 ASFVTGADYAVDGG 244 A +T + VDGG Sbjct: 243 AGHITMHNLCVDGG 256
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 28.5 bits (63), Expect = 0.049 Identities = 28/107 (26%), Positives = 42/107 (39%), Gaps = 12/107 (11%) Query: 166 ARVTRRPFIVSTPHGDIL---------PEEARFTVRLHDLATRV-EVLDQTATVVPGRAA 215 ARVT +S PHG+++ P+ A ++ L A + L P + Sbjct: 327 ARVTVSGGSLSAPHGNVIETGGARRFAPQAAPLSITLQAGAHAQGKALLYRVLPEPVKLT 386 Query: 216 ASPAAYPRAVLLHANQAVSFDGNSAGPVGVASADAAAWLHGRLAVVD 262 + A + ++ S G S GP+ VA A A W G VD Sbjct: 387 LTGGADAQGDIVATELP-SIPGTSIGPLDVALASQARW-TGATRAVD 431
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 34.5 bits (79), Expect = 1e-04 Identities = 12/64 (18%), Positives = 23/64 (35%), Gaps = 1/64 (1%) Query: 100 QLFEQLDAEAFAFVACDFSLADGSPAPPYYLGNVLRRLDALDEASSRVRIKLDHNYQTGE 159 Q Q D ++ + P P++ L + L EA S + + + E Sbjct: 81 QAMGQYDLAIHSYSYG-AIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTE 139 Query: 160 NEKL 163 ++L Sbjct: 140 FKEL 143
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.8 bits (67), Expect = 0.022 Identities = 16/62 (25%), Positives = 25/62 (40%), Gaps = 11/62 (17%) Query: 14 WMGALLLRPATRIGLGVL---VIGGFLGGVTFLALFNTGMNATNTEAFCISCHSMRDTVL 70 +M A G G++ V+GG +GG + A F A N F C + ++ Sbjct: 135 FMSAC-------FGFGMVAGPVLGGLMGGFSPHAPFFAA-AALNGLNFLTGCFLLPESHK 186 Query: 71 PE 72 E Sbjct: 187 GE 188
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 30.7 bits (69), Expect = 0.007 Identities = 23/120 (19%), Positives = 44/120 (36%), Gaps = 7/120 (5%) Query: 150 LAQRLRATPDDADGWYTLARSYETLGRYGDAAVAYREVLRLVPAQPQVLADLADAL--LS 207 +A + D + Y+LA + G+Y DA ++ + L + L + Sbjct: 25 IAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMG 84 Query: 208 ANQGAPDAASIAAVAQALAANPDQPKALALAGMMALRRGDAAQALEYWQRLQALLPPDSE 267 A + S A+ +P+ A L++G+ A+A Q L+ +E Sbjct: 85 QYDLAIHSYSYGAIMD-----IKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTE 139
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 257 bits (657), Expect = 5e-90 Identities = 97/201 (48%), Positives = 137/201 (68%), Gaps = 3/201 (1%) Query: 1 MAKLQRDAVIAAALDLLNEVGVDGLTTRKLAERLGVQQPALYWHFKSKQALLDALSDAMM 60 MA+L R++VI AAL+LLNE G+DGLTTRKLA++LG++QP LYWH K+K+ALLDAL+ ++ Sbjct: 1 MARLNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEIL 60 Query: 61 -REHMHTLPSPGGPWKEFLYANARSFRRALLAYRDGARIHAGTRPAEPQYDRVQAQIKLL 119 R H ++LP+ G W+ FL NA SFRRALL YRDGA++H GTRP E QYD V+ Q++ + Sbjct: 61 ARHHDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHLGTRPDEKQYDTVETQLRFM 120 Query: 120 CDAGFTPLRAANALVAISHYVVGSVMEQQAGEAAAPERVAPP--APPPALARTMKALDRQ 177 + GF+ A+ A+SH+ +G+V+EQQ AA +R A P PP L ++ +D Sbjct: 121 TENGFSLRDGLYAISAVSHFTLGAVLEQQEHTAALTDRPAAPDENLPPLLREALQIMDSD 180 Query: 178 GPDATFEYGLAMMLDGLSPDL 198 + F +GL ++ G L Sbjct: 181 DGEQAFLHGLESLIRGFEVQL 201
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 387 bits (996), Expect = e-135 Identities = 239/396 (60%), Positives = 287/396 (72%), Gaps = 1/396 (0%) Query: 2 PDRAIALLLFIVTLDAAGAGLIMPVLPGLLDQLGDAAATPAHYGVLLSLYALAQCLAAPV 61 P+R + ++L V LDA G GLIMPVLPGLL L + AHYG+LL+LYAL Q APV Sbjct: 3 PNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPV 62 Query: 62 LGALSDRYGRRPVLLVSLAGAAVDYLVMAAAPALWVLYAGRILAGITGATGAVAGACIAD 121 LGALSDR+GRRPVLLVSLAGAAVDY +MA AP LWVLY GRI+AGITGATGAVAGA IAD Sbjct: 63 LGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD 122 Query: 122 AGDPSRRARRFGQLSACFGLGMILGPALGGLAGLAGARMPFVAAAAANGVAFLTALAWLP 181 D RAR FG +SACFG GM+ GP LGGL G PF AAAA NG+ FLT LP Sbjct: 123 ITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLP 182 Query: 182 ESRRGARAPWSWRALDPIGGLRQALGGKNLAGLLWVFLVMQMAGQVPGSLWVLYGQDRFQ 241 ES +G R P AL+P+ R A G +A L+ VF +MQ+ GQVP +LWV++G+DRF Sbjct: 183 ESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFH 242 Query: 242 WDAAAVGLSLAGFGALHAVAQATLPGPLSARLGERGALVVGMAADAAGYVLLACATQGWM 301 WDA +G+SLA FG LH++AQA + GP++ARLGER AL++GM AD GY+LLA AT+GWM Sbjct: 243 WDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWM 302 Query: 302 AAPLMLLLAAGGVGAPALQALLSARAGAGSQGQLQGAMNSLASAAAIAGPLAFTTLYAAS 361 A P+M+LLA+GG+G PALQA+LS + QGQLQG++ +L S +I GPL FT +YAAS Sbjct: 303 AFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAAS 362 Query: 362 VGGWTGWPWVAGAALYLLCAPTLARLGAPGDAAPRA 397 + W GW W+AGAALYLLC P L R G A RA Sbjct: 363 ITTWNGWAWIAGAALYLLCLPAL-RRGLWSGAGQRA 397
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.4 bits (71), Expect = 0.007 Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 22/141 (15%) Query: 74 LGGVIFGHYGDRIGRKSMLLITLLLMGVPTILIGLIPSYEQIGYWAAVLLVLMRFLQGIA 133 +G ++G D++G K +LL +++ ++ IG +G+ LL++ RF+QG Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSV-IGF------VGHSFFSLLIMARFIQGA- 115 Query: 134 VGGEWGGAVLMAV--EHAPQGKKGFFGSLPQAGVAPGLILSSLAMGAVAGLPEQDMLS-- 189 G A++M V + P+ + G A GLI S +AMG G M++ Sbjct: 116 -GAAAFPALVMVVVARYIPKENR---------GKAFGLIGSIVAMGEGVGPAIGGMIAHY 165 Query: 190 WGWRLPFLASVVLLAVGWFIR 210 W L ++ + F+ Sbjct: 166 IHWSYLLLIPMITIITVPFLM 186
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 128 bits (322), Expect = 4e-38 Identities = 82/249 (32%), Positives = 116/249 (46%), Gaps = 12/249 (4%) Query: 8 VLVTGGASGIGLAVARGLLGAGRRVLVADVSQERLDEVRGL--APADRLGCVRMDVSDEA 65 +TG A GIG AVAR L G + D + E+L++V A A DV D A Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 66 QVSEAIARLESDFGPIAGLVNSAGIGRDVPFLETDAALLRRILEVNLVGSFVVAREAARR 125 + E AR+E + GPI LVN AG+ R VN G F +R ++ Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKY 130 Query: 126 MRDRGRGSIVNIASVSGIRGNAGRAAYGASKGGVVTLTRVMAVELAAYGIRVNAVAPGPI 185 M DR GSIV + S AAY +SK V T+ + +ELA Y IR N V+PG Sbjct: 131 MMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGST 190 Query: 186 ETPLVSQMHTDEARAA---------WRRVVPQHRYAAPEELNGTIGWLLDESQSSYVTGQ 236 ET + + DE A ++ +P + A P ++ + +L+ Q+ ++T Sbjct: 191 ETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSG-QAGHITMH 249 Query: 237 VICVDGGFT 245 +CVDGG T Sbjct: 250 NLCVDGGAT 258
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 27.9 bits (62), Expect = 0.009 Identities = 11/45 (24%), Positives = 22/45 (48%) Query: 6 SAGIRLALAACLIFAALFAVVGGWTTGYSLESVIWLALTGAIFGA 50 A +A++ ++F L A+ W+ S+ V+ L + G + A Sbjct: 871 QAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAA 915
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 37.9 bits (88), Expect = 6e-05 Identities = 26/145 (17%), Positives = 52/145 (35%), Gaps = 1/145 (0%) Query: 49 IAASLDASTGRVGWLMVVPGLLAAL-CAPLVVMGARGVDRRRILCGLLLLLAGANLGSAL 107 IA + W+ L ++ A + + +R +L G+++ G+ +G Sbjct: 40 IANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVG 99 Query: 108 APDMAWFLAARVLVGVCIGGIWAVAGGLAGRLVPPAAIGMATAVIFGGVAVASVLGVPLG 167 + + AR + G A+ + R +P G A +I VA+ +G +G Sbjct: 100 HSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIG 159 Query: 168 ALIGNLAGWRSAFGAMAVLSAAVLL 192 +I + W + V Sbjct: 160 GMIAHYIHWSYLLLIPMITIITVPF 184
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 36.0 bits (83), Expect = 2e-04 Identities = 31/160 (19%), Positives = 60/160 (37%), Gaps = 1/160 (0%) Query: 25 LLALALAGFIAIMTETVPAGLLPQIGLGLGVSEALAGQLVTLFAAGSVLAAIPIIVATRG 84 L+ L + F +++ E V LP I A + T F + + Sbjct: 16 LIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 85 WNRRPLLLLAIGGLCIFNVVTALS-AHYALALAARFGGGMAAGLLWGLLAGYARRMVATR 143 + LLL I C +V+ + + ++L + ARF G A L+ R + Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 144 QQGRALAVVGAGQPLALCLGVPAGAWLGSLMDWRGVFWLM 183 +G+A ++G+ + +G G + + W + + Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIP 175
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 77.4 bits (190), Expect = 6e-20 Identities = 31/157 (19%), Positives = 59/157 (37%), Gaps = 3/157 (1%) Query: 13 DAAMQVFWRRGYAATSVQDLVDGTGLGRGSLYNAFGSKQGLYEAALRRYHELTAANLDLL 72 D A+++F ++G ++TS+ ++ G+ RG++Y F K L+ Sbjct: 18 DVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEY 77 Query: 73 A--RPGNARERIGRLLDFIADDELREPSRRGCLVA-NASLEMAGQDEMVAELVRRNFQRL 129 PG+ + +L + + + E RR + E G+ +V + R Sbjct: 78 QAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLES 137 Query: 130 EKALEQILAEGQANGEIDAGRSPRALARFIVTTVQGL 166 +EQ L + A R A + + GL Sbjct: 138 YDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL 174
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 44.4 bits (105), Expect = 5e-07 Identities = 67/359 (18%), Positives = 116/359 (32%), Gaps = 39/359 (10%) Query: 48 GDWGAVLGYFGYGYMVGALFGGMLADRYGPRKVWIVAGVTWSIFEIATAWAGDFGLAFLG 107 +G +L + A G L+DR+G R V +V+ ++ A A + ++G Sbjct: 43 AHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIG 102 Query: 108 GSALAGFATIRILFGAAEGPAYSIINKTIANWATPRERGFVVGFGLLSTPLGALLTAPVA 167 RI+ G G ++ IA+ ER FG +S G + A Sbjct: 103 ----------RIVAGIT-GATGAVAGAYIADITDGDER--ARHFGFMSACFGFGMVAGPV 149 Query: 168 VGLLSLTGSWRAMFYILGAAGLLVLVLFMRIFTDRPDTNPRVSPAELREIQAARAEQAAA 227 +G L S A F+ AA L L F P + Sbjct: 150 LGGLMGGFSPHAPFFA--AAALNGLNFLTGCFLLPESHKGERRPLRREALNPLA------ 201 Query: 228 GQGGDAPALPWWSFFRSKTLVLNTLGYFSFNYVNFLLLTWTPKYLQDTFGYSLSSLWYMG 287 + W ++ +F V + + +D F + +++ G Sbjct: 202 -------SFRWARGMTVVAALMAV--FFIMQLVGQVPAALWVIFGEDRFHWDATTI---G 249 Query: 288 MIPWTGACVTVLLGGRISDMLARRTGNLKIARSWFAAGCLLATTLCFLLVSQAQSVFAVI 347 + + L I+ +A R G + G + T LL + A Sbjct: 250 ISLAAFGILHSLAQAMITGPVAARLGERRA----LMLGMIADGTGYILLAFATRGWMAFP 305 Query: 348 ALMTLANALNAMPNSVYWAVVIDTAPASRVGTFSGLMHFFANIASILAPTLTGYLAARH 406 ++ LA+ MP A++ R G G + ++ SI+ P L + A Sbjct: 306 IMVLLASGGIGMP--ALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAAS 362
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 38.1 bits (88), Expect = 7e-05 Identities = 26/188 (13%), Positives = 53/188 (28%), Gaps = 12/188 (6%) Query: 14 PLLFALPAAPAVAGMDCARARTPTEKTLCADAALYRLDDELGAAYARLRAAQQPGQNEAL 73 P A P+ + ++ + T + DA + A A+ NE Sbjct: 1027 PPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVA 1086 Query: 74 RQAQRGWLKQRDACDSDAECLRQRYDTRLAELQAQQSRALAYRPDDIDRLALEDLRQAIE 133 + Q A ++ E + + + ++ E ++ E Sbjct: 1087 QSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQ--SETVQPQAE 1144 Query: 134 AARQSNPEFAVETVLAARSLKAEATAIRNERAADGDGPARLPAARPAGVTEDEWAAVLAS 193 AR+++P ++ E + N A + VTE S Sbjct: 1145 PARENDPTVNIK----------EPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNS 1194 Query: 194 DLESDAEE 201 +E+ Sbjct: 1195 VVENPENT 1202
>PilS_PF08805#PilS N terminal Length = 185 Score = 30.7 bits (69), Expect = 0.003 Identities = 17/89 (19%), Positives = 33/89 (37%), Gaps = 8/89 (8%) Query: 4 RRVAPHAQAGFTLIEVLVALALMALVSLMAWRGLDSVSSARDW--IARQADDTDAIVRAL 61 RR G TL+EVL+ + ++ +++ A++ V S A +++L Sbjct: 19 RRKKEQ-DKGATLMEVLLVVGVIVVLAASAYKLYSMVQSNIQSSNEQNNVLTVIANMKSL 77 Query: 62 GQMGRDVEMAYNGPSFAAPGIDARVFTSG 90 GR Y ++ + S Sbjct: 78 KFQGR-----YTDSNYIKTLYAQGLLPSD 101
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 117 bits (294), Expect = 5e-33 Identities = 38/150 (25%), Positives = 70/150 (46%) Query: 8 STVFIVDDDEAVRDSLRWLLEANGYRVRAYASGESFLEDYDPSQIGVLIADVRMPGMSGL 67 +T+ + DDD A+R L L GY VR ++ + +++ DV MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 68 ELQEQLIARNAPLPIVFITGHGDVPMAVSTMKKGAVDFLEKPFNESDLREIVARMLEQAT 127 +L ++ LP++ ++ A+ +KGA D+L KPF+ ++L I+ R L + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 128 QRVSKHQAQKDHEAMLARLTAREQQVLERI 157 +R SK + L +A Q++ + Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVL 153
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 37.7 bits (87), Expect = 1e-04 Identities = 33/156 (21%), Positives = 50/156 (32%), Gaps = 15/156 (9%) Query: 79 AAPAAKEEPKAEAPKQAAAAAPAAKAEAAAPAASSGPVEIEVPDIGDFKEVEVIEVMVAV 138 A P+ E AE KQ + + +A A + V E V Sbjct: 1031 ATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKE----------AKSNVKANT 1080 Query: 139 GDTIKAEQSLITVESDKALMEIPASQGGVVKEVKVKVGDKVAKGSVVVVVEGSAPAAAAA 198 A+ T E+ + A+ KE K KV + V V +P + Sbjct: 1081 QTNEVAQSGSETKETQTTETKETATVE---KEEKAKV-ETEKTQEVPKVTSQVSPKQEQS 1136 Query: 199 PAAKAEAASARSEAPAAKAEAPAAP-ATPAVGSRPA 233 + +A AR P + P + T A +PA Sbjct: 1137 ETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPA 1172
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.0 bits (78), Expect = 0.002 Identities = 19/85 (22%), Positives = 32/85 (37%), Gaps = 8/85 (9%) Query: 39 TVESDKASMEIPASTGGVVKSINVKVGDKVAEGSVVLEVEASDAAPAAKQAPKADAPKAE 98 + S EI +VK I VK G+ V +G V+L++ A A AD K + Sbjct: 89 KLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAE--------ADTLKTQ 140 Query: 99 APKAEAKPAAAAPAAATFKGSADAE 123 + +A+ + + Sbjct: 141 SSLLQARLEQTRYQILSRSIELNKL 165
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 70.1 bits (171), Expect = 2e-16 Identities = 71/266 (26%), Positives = 119/266 (44%), Gaps = 19/266 (7%) Query: 1 MADHSIKGKVVLIAGGAKNLGGLIARDLAQHGAKAVAIHYNSAASKADADATVAAIQAAG 60 M I+GK+ I G A+ +G +AR LA GA A+ YN + V++++A Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKL----EKVVSSLKAEA 56 Query: 61 AKAVALQADLTTAGAVEKLFADAVAAVGRPDIAINTVGKVLKKPLTEISEAEYDEMSAVN 120 A A AD+ + A++++ A +G DI +N G + + +S+ E++ +VN Sbjct: 57 RHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVN 116 Query: 121 AKTAFFFLKEAGRHVND--NGKVCTLVTSLLGAFTPFYAAYAGTKAPVEHYTRAASKEFG 178 + F + +++ D +G + T+ ++ G AAYA +KA +T+ E Sbjct: 117 STGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 179 ARGISVTAVGPGPMDTPFFYPAEGADAVAYHKTAAALSPFSKTGL--------TDIEDVV 230 I V PG +T + + A +L F KTG+ +DI D V Sbjct: 177 EYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETF-KTGIPLKKLAKPSDIADAV 235 Query: 231 PFIRHLVSD-GWWITGQTILINGGYT 255 F LVS IT + ++GG T Sbjct: 236 LF---LVSGQAGHITMHNLCVDGGAT 258
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.1 bits (75), Expect = 0.001 Identities = 18/80 (22%), Positives = 36/80 (45%), Gaps = 2/80 (2%) Query: 137 APRTADAPPPQPGATDSVPPSAAPSPDDAAPTPHIQGQSAASAAPAAAAIPAREGAAPHA 196 P+ P+ +++V P A P+ ++ PT +I+ + + A PA+E + + Sbjct: 1122 VPKVTSQVSPKQEQSETVQPQAEPAREN-DPTVNIKEPQSQTNTTADTEQPAKE-TSSNV 1179 Query: 197 DRPAMPKPTLRITEIPAENP 216 ++P T+ ENP Sbjct: 1180 EQPVTESTTVNTGNSVVENP 1199
>FLAGELLIN#Flagellin signature. Length = 507 Score = 217 bits (555), Expect = 3e-66 Identities = 237/564 (42%), Positives = 290/564 (51%), Gaps = 59/564 (10%) Query: 2 AAVINTNYLSLVAQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGMAIANRFTANVKGL 61 A VINTN LSL+ QNNLNKSQS+L +AIERLSSGLRINSAKDDAAG AIANRFT+N+KGL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 TQAARNANDGISLAQTTEGAASEINTHLQRVRELSVQAANGSYSQEQLNSMQDEINQRLS 121 TQA+RNANDGIS+AQTTEGA +EIN +LQRVRELSVQA NG+ S L S+QDEI QRL Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 DIDRISQQTDFNGVKVLSGNAKPLTLQVGANDGETITLNLTEISVKTLGLDGFNVNGTGV 181 +IDR+S QT FNGVKVLS + + + +QVGANDGETIT++L +I VK+LGLDGFNVNG Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQ-MKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 182 TQNRTATVSDLQAAGGKAGAGAAANDWTVTTNHAAATAEQAFGKLENGNTVVVGGTTYTY 241 S G A A + A T A + G T Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 242 DAANGNFTFQNTTKGATPADSTANLAKLASSLTPATGTSTGTYTNNASASTTFEVDATGN 301 DA N T +T + A A D G Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAI----------------KGGKEGDTFDYKGV 283 Query: 302 LTIGGKAAYLAATGELSTNNPGGGAQATLTDV--LTTTSKAAAGTASISIGGKTFNSTGT 359 G++ST G T+ D+ AA +S ++ N T Sbjct: 284 TFTIDTKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFT 343 Query: 360 VDEVTYTDTVAKDALLATFKAGAAGSEINLGQGITAAKLTFTTGTSTDTWVDGSGSFTRT 419 D+ T ++ L A Sbjct: 344 FDDKTKNESAKLSDLEANNAVKG------------------------------------- 366 Query: 420 QKYDTTYTVDPNTGKATVKSGTGTGDYAPKVGATAYVNSSGKLTTETTSKGGKTSDPLKT 479 ++ TV+ A T S + + + T++PL + Sbjct: 367 ---ESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPLAS 423 Query: 480 LDAAFTKLDKLTGELGAVQNRLESTIANLNNVVNNLSSARSRIQDADYATEVSNMSKAQI 539 +D+A +K+D + LGA+QNR +S I NL N V NL+SARSRI+DADYATEVSNMSKAQI Sbjct: 424 IDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKAQI 483 Query: 540 LQQAGTSVLAQANQVPQTVLSLLR 563 LQQAGTSVLAQANQVPQ VLSLLR Sbjct: 484 LQQAGTSVLAQANQVPQNVLSLLR 507
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 36.7 bits (85), Expect = 1e-04 Identities = 12/44 (27%), Positives = 23/44 (52%) Query: 4 VIGFLVVIVSVIGSFVALGGHMGALYQPFELTLIFGAAFGAFLA 47 ++G +V+ +V GG GA+Y+ F +T++ A +A Sbjct: 442 LVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVA 485
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 44.2 bits (104), Expect = 4e-07 Identities = 34/126 (26%), Positives = 56/126 (44%), Gaps = 11/126 (8%) Query: 167 FATGRAEVQPYMRDILRELGPVLNEL---PNKVSISGHTDASQYARGERAYSNWELSADR 223 F +A ++P + L +L L+ L V + G+TD G AY N LS R Sbjct: 223 FNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDR----IGSDAY-NQGLSERR 277 Query: 224 ANASRQELVAGGMNESKVMRIQGLSSSMSLVKDDPYAAVNRRISLVVLNQSTQRRIENEN 283 A + L++ G+ K+ +G+ S + V + V +R +L+ + RR+E E Sbjct: 278 AQSVVDYLISKGIPADKI-SARGMGES-NPVTGNTCDNVKQRAALIDC-LAPDRRVEIEV 334 Query: 284 AAAADV 289 DV Sbjct: 335 KGIKDV 340
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 80.6 bits (199), Expect = 3e-21 Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 2/104 (1%) Query: 6 TLTGAGWKVLTAGNGQEALEVAKSHPVDLVVSDWNMPVMGGLQLIQGLREQEQYLDVPVL 65 L+ AG+ V N + DLVV+D MP L+ ++ + D+PVL Sbjct: 22 ALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIK--KARPDLPVL 79 Query: 66 VLTTEDDVDSKMAARDLGVCGWLSKPVDPDVLVELASELLDEQS 109 V++ ++ + + A + G +L KP D L+ + L E Sbjct: 80 VMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123
>PF06580#Sensor histidine kinase Length = 349 Score = 43.3 bits (102), Expect = 2e-06 Identities = 23/151 (15%), Positives = 51/151 (33%), Gaps = 52/151 (34%) Query: 414 ELDKSLIERIIDPLT--HLVRNSLDHGIETPEKRVAAGKDPVGQLVLSAQHNGGNIVIEV 471 +++ ++++ + P+ LV N + HGI G+++L + G + +EV Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTLEV 296 Query: 472 SDDGAGLNREKILKKAMAQGLPVNENSPDDEIWQLIFAPGFSTAEKVTDISGRGVGMDVV 531 + G+ + G G+ V Sbjct: 297 ENTGSLALKN--------------------------------------TKESTGTGLQNV 318 Query: 532 RRNIQDMGG---HVQLSCEPGNGTTTRIVLP 559 R +Q + G ++LS + G +++P Sbjct: 319 RERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 53.3 bits (128), Expect = 6e-10 Identities = 36/152 (23%), Positives = 64/152 (42%), Gaps = 25/152 (16%) Query: 27 ARELIKKHNPDVLTLDVEMPRMDGLDFLEKLMRLRP-MPVVMVSSLTERGGEITLRALEL 85 I + D++ DV MP + D L ++ + RP +PV+++S+ ++A E Sbjct: 39 LWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKARPDLPVLVMSAQNT--FMTAIKASEK 96 Query: 86 GAIDFVTKPKLGIRDGLLEYTEIIADKIRAASRAKLRAPSPHAPAAAPAPMLRRPLSSSE 145 GA D++ KP + TE+I RA + K R + S + Sbjct: 97 GAYDYLPKP--------FDLTELIGIIGRALAEPKRRPS-------------KLEDDSQD 135 Query: 146 KLVIVGASTGGTEAIREVLQPLPPDSPAILIT 177 + +VG S E R + + + D ++IT Sbjct: 136 GMPLVGRSAAMQEIYRVLARLMQTDLT-LMIT 166
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.9 bits (210), Expect = 2e-22 Identities = 31/107 (28%), Positives = 53/107 (49%), Gaps = 3/107 (2%) Query: 5 GIKILVVDDFPTMRRIIRNLLKELGFENVDEAEDGAIGLEKLRNGGFQFVVSDWNMPNLD 64 G ILV DD +R ++ L G++ V + A + G VV+D MP+ + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYD-VRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 65 GLEMLKQIRADASLASLPVLMVTAEAKKENIVAAAQAGANGYVVKPF 111 ++L +I+ LPVL+++A+ + A++ GA Y+ KPF Sbjct: 62 AFDLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 30.0 bits (67), Expect = 0.026 Identities = 53/323 (16%), Positives = 112/323 (34%), Gaps = 36/323 (11%) Query: 62 AQLAQEQARAAEALAASGAQIAALSA-----------STSTHAREIADVSGQNLRAAEQA 110 A+ A AAEA A + A AL+ ++ +++ N A + Sbjct: 67 AEQAARAKAAAEAQAKAKANRDALTQRLKDIVNEALRHNASRTPSATELAHANNAAMQAE 126 Query: 111 LAELSEVK-ERVDRMTREMA--AFTDVVGQLTDRARSVGDISKLIKDIALQTQLLALNAG 167 L K E R E A AF + + + R + + +K + + LA A Sbjct: 127 DERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQLKLAEAEEKRLA--AL 184 Query: 168 VEAARAGD-AGRGFAVVASEVGRLAERVNAATSDIG-----------RHTGEMLELVDST 215 E A+A + A + + SEV ++ + S + G+ EL ++ Sbjct: 185 SEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAGKRNELAQAS 244 Query: 216 QRQTGTLREDVDASGAVLDKTR-----QDFQHFVRDFDNMNRQVGEVVQAIGEVDATNHG 270 + S D + + + V + +V + ++ N Sbjct: 245 AKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASETRINRINAD 304 Query: 271 MSQDVSRIAALSADVRERVASMS-GEIDRIRRQTESVQEVLSDMRTGNTAF-DRLSEAL- 327 ++Q I+ +S + +A + E + + Q + + D +F L+E Sbjct: 305 ITQIQKAISQVSNNRNAGIARVHEAEENLKKAQNNLLNSQIKDAVDATVSFYQTLTEKYG 364 Query: 328 DAFRAAATRLLEQARARGLDVFD 350 + + A L ++++ + + + Sbjct: 365 EKYSKMAQELADKSKGKKIGNVN 387
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 366 bits (940), Expect = e-128 Identities = 93/343 (27%), Positives = 176/343 (51%), Gaps = 2/343 (0%) Query: 8 EKTEAASPRRLEKAREEGQIARSRELGTFMMLAVGVGAIWAGGGTIYKGLSGVLRNGLAF 67 EKTE +P+++ AR++GQ+A+S+E+ + ++ + ++ S ++ + Sbjct: 4 EKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLML--IPA 61 Query: 68 DQRVVADPGVMVEQAVNGFGHALMVILPIFGLLAVIAVLSSVLLGGIVISGKPLSPNFSK 127 +Q + + N + P+ + A++A+ S V+ G +ISG+ + P+ K Sbjct: 62 EQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKK 121 Query: 128 LSLFAGLKRMFSAQTVVELIKALAKAMLVGGVAVWILWRYHDDMLGLMHVAPSAALTKAL 187 ++ G KR+FS +++VE +K++ K +L+ + I+ +L L Sbjct: 122 INPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLG 181 Query: 188 SLVAMCCAFIVASLLVIVLLDVPWQIWSHLKKLRMSKEDVRQEHKESEGDPHTKARIRQQ 247 ++ +VI + D ++ + ++K+L+MSK+++++E+KE EG P K++ RQ Sbjct: 182 QILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQF 241 Query: 248 QRQAARRRMMSEVPKADVVVTNPTHYAVALKYEEDKNGAPRVLAKGTGLIAAKIRELAAE 307 ++ R M V ++ VVV NPTH A+ + Y+ + P V K T +R++A E Sbjct: 242 HQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEE 301 Query: 308 HRIPTLEAPPLARALHQHVELGQEIPAELYTAVAEVLAWVFQL 350 +P L+ PLARAL+ + IPAE A AEVL W+ + Sbjct: 302 EGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQ 344
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 40.0 bits (93), Expect = 3e-05 Identities = 20/77 (25%), Positives = 26/77 (33%), Gaps = 3/77 (3%) Query: 144 PEQEVLQEPVARQAPPAAVP---PAAPVVAAPAPAAPVRVEMPVLPPARPAPSVAPSPMA 200 L+ P A Q PP V P + P APV +E P P V Sbjct: 55 VAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQP 114 Query: 201 RMPDAPLRNGPAMPPAA 217 + P+ + PA P Sbjct: 115 KRDVKPVESRPASPFEN 131 Score = 38.8 bits (90), Expect = 6e-05 Identities = 28/132 (21%), Positives = 38/132 (28%), Gaps = 7/132 (5%) Query: 89 PPPAMPASYGLGAHAAMAPPPHTAPIAPPAAPQPGYAVPSRSIAAYQSAYATPGVPEQEV 148 P PA P S + A A + PP P P P A + + + Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEP----IPEPPKEAPVVIEKPKP 99 Query: 149 LQEPVARQAPPAAVPPAAPVVAAPAPAAPVRVEMPVLPPARP--APSVAPSPMARMPDAP 206 +P + P PA+P P P + A + P Sbjct: 100 KPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRA 159 Query: 207 L-RNGPAMPPAA 217 L RN P P A Sbjct: 160 LSRNQPQYPARA 171 Score = 38.0 bits (88), Expect = 1e-04 Identities = 22/118 (18%), Positives = 33/118 (27%), Gaps = 5/118 (4%) Query: 71 AGTPAPQAQPAPVAPRLQPPPAMPASYGLGAHAAMAPPPHTAPIAPPAAPQPGYAVPSRS 130 A PQA P P ++P P A + P P P R Sbjct: 58 ADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRD 117 Query: 131 IAAYQSAYATPGVPEQEVLQEPVARQAPPAAVPPAAPVVAAPAPAAPVRVEMPVLPPA 188 + +S A+P P + A + PV + + + P P Sbjct: 118 VKPVESRPASPFENTA-----PARPTSSTATAATSKPVTSVASGPRALSRNQPQYPAR 170 Score = 35.7 bits (82), Expect = 5e-04 Identities = 22/138 (15%), Positives = 33/138 (23%), Gaps = 7/138 (5%) Query: 73 TPAPQAQPAPVAPRLQPPPAMPASYGLGAHAAMAPPPHTAPIAPPAAPQPGYAVPSRSIA 132 PA VAP PP + P P PI P P + Sbjct: 45 APAQPISVTMVAPADLEPPQAVQP---PPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKP 101 Query: 133 AYQSAYATPGVPEQEVLQEPVARQAPPAAVPPAAPVVAAPAPAAPVRVEMPVLPPARPAP 192 + + ++ +R A P AP + A + + P Sbjct: 102 KPKPKPVKKVEQPKRDVKPVESRPASPF--ENTAPARPTSSTATAATSKPVTSVASGPRA 159 Query: 193 SVAPSPMARMPDAPLRNG 210 P + P Sbjct: 160 LSRNQP--QYPARAQALR 175
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 29.5 bits (66), Expect = 0.004 Identities = 12/41 (29%), Positives = 20/41 (48%) Query: 96 SMPNVDPVAETVNMIAASRSYQANVEVLNTAKSLMQKTLTI 136 S+ V+ E N+ + Y AN +VL TA ++ + I Sbjct: 505 SISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.0 bits (101), Expect = 2e-06 Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 9/102 (8%) Query: 386 QYTNGETSIVGTIVLAD-FANLQGLQPVGNNAWKETATSGQPILGQPGSNGLSKVVGQAT 444 + ++ G D +A+L +GN TAT N ++++ Q Sbjct: 453 DLQSNSKTVGGAKSFNDAYASLVSD--IGNK----TATLKT--SSATQGNVVTQLSNQQQ 504 Query: 445 ESSNVDMSKELVNMIIAQRTYQANSQTIKTQDEIMQVLMNLK 486 S V++ +E N+ Q+ Y AN+Q ++T + I L+N++ Sbjct: 505 SISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 31.5 bits (71), Expect = 0.008 Identities = 15/52 (28%), Positives = 23/52 (44%), Gaps = 4/52 (7%) Query: 1 MNAAAQNLDVIGNNIANSGTVGFKSSTASFAD----VYASSRVGLGTKVAAI 48 +NAA L+ NNI++ G+ T A + A VG G V+ + Sbjct: 11 LNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGV 62
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 42.3 bits (99), Expect = 1e-06 Identities = 11/41 (26%), Positives = 22/41 (53%) Query: 221 ETSNVNVAEELVNMITTQRAYEMNSKAVKTSDEMLARLTQL 261 S VN+ EE N+ Q+ Y N++ ++T++ + L + Sbjct: 505 SISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545 Score = 39.6 bits (92), Expect = 8e-06 Identities = 15/78 (19%), Positives = 32/78 (41%), Gaps = 14/78 (17%) Query: 4 SLWIAKTGLEGQQTSMDVISNNLANVSTNGFKRGRAVFQDLMYQTLRQPGAQVGDATQLP 63 + A +GL Q +++ SNN+++ + G+ R + + L Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANSTLG 48 Query: 64 SGLQLGTGARVAATERIH 81 +G +G G V+ +R + Sbjct: 49 AGGWVGNGVYVSGVQREY 66
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 197 bits (503), Expect = 3e-66 Identities = 118/215 (54%), Positives = 148/215 (68%), Gaps = 6/215 (2%) Query: 3 VAGCAMIPPEPIVTGPTTAAPPPPPMPAAQPTGSIY---QPTTYGNYPLFEDRRPRNVGD 59 + GCA IP P+V G T+A P P P P A GSI+ QP YG PLFEDRRPRN+GD Sbjct: 19 LTGCAWIPSTPLVQGATSAQPVPGPTPVA--NGSIFQSAQPINYGYQPLFEDRRPRNIGD 76 Query: 60 IVTIVLNEKTNASKNVATNTNRSGSASLGITAAPSFMDSW-ANANLNTDAKGGNVAQGKG 118 +TIVL E +ASK+ + N +R G + G P ++ NA + +A GGN GKG Sbjct: 77 TLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNARADVEASGGNTFNGKG 136 Query: 119 DSTANNAFTGTITTTVVGVMSNGNLQVAGEKQIAINRGSEYVRFSGVVDPRSITGTNTVS 178 + A+N F+GT+T TV V+ NGNL V GEKQIAIN+G+E++RFSGVV+PR+I+G+NTV Sbjct: 137 GANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVP 196 Query: 179 STQVADARIEYRSKGVMDEVQTMGWLQRFFLIASP 213 STQVADARIEY G ++E Q MGWLQRFFL SP Sbjct: 197 STQVADARIEYVGNGYINEAQNMGWLQRFFLNLSP 231
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 381 bits (981), Expect = e-134 Identities = 154/357 (43%), Positives = 216/357 (60%), Gaps = 9/357 (2%) Query: 14 LLAGASAAHAERLKDLASIQGVRGNQLIGYGLVVGLDGSGDQVRQTPFTQQSLTNMLSQL 73 L + A R+KD+AS+Q R NQLIGYGLVVGL G+GD +R +PFT+QS+ ML L Sbjct: 19 LSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMRAMLQNL 78 Query: 74 GITVPAGSNMQLKNVAAVMVTTTLPAFARPGQTLDVVVSSMGNAKSLRGGTLLMTPLKGA 133 GIT G + KN+AAVMVT LP FA PG +DV VSS+G+A SLRGG L+MT L GA Sbjct: 79 GITTQGGQS-NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIMTSLSGA 137 Query: 134 DSQVYAIAQGNILVGGAGASAGGSSVQINQLNGGRISGGAIVERGVPTTFARDGYIYLEM 193 D Q+YA+AQG ++V G A +++ R+ GAI+ER +P+ F + L++ Sbjct: 138 DGQIYAVAQGALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSVNLVLQL 197 Query: 194 NNTDFGTAQNVVNALNR----KFGQGTATALDGRVVQVRTPMEQASQARFLSQVEDLQVT 249 N DF TA V + +N ++G A D + + V+ P A R ++++E+L V Sbjct: 198 RNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKP-RVADLTRLMAEIENLTVE 256 Query: 250 RAPTVAKVIINARTGSVVMNRTVMIEEAAVAHGNLSVIINRQNQVSQPDTPFTEGQTVVV 309 T AKV+IN RTG++V+ V I AV++G L+V + QV QP PF+ GQT V Sbjct: 257 -TDTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQP-APFSRGQTAVQ 314 Query: 310 PNTQIEVRQDNGSLQRVTTSANLADVVKGLNALGATPQDLLAILQAMKTAGALRAEL 366 P T I Q+ + + +L +V GLN++G ++AILQ +K+AGAL+AEL Sbjct: 315 PQTDIMAMQEGSKV-AIVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGALQAEL 370
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 226 bits (578), Expect = 9e-75 Identities = 128/309 (41%), Positives = 186/309 (60%), Gaps = 13/309 (4%) Query: 16 SVFDMGRLSDLKRDVTKDPANPGTEQQKQVAKQFEALFLQMMLKRMREATPKEGLFDSQQ 75 + +D L++LK +DPA + VA+Q E +F+QMMLK MR+A PK+GLF S+ Sbjct: 11 AAWDAQSLNELKAKAGEDPAA----NIRPVARQVEGMFVQMMLKSMRDALPKDGLFSSEH 66 Query: 76 TQMLQSMADEQLALHL-ATPGIGLSQSILAQMQQGKPGDLPAEAVQRLGQGTDLDFQTGG 134 T++ SM D+Q+A + A G+GL++ ++ QM +P + + +T Sbjct: 67 TRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPM----KFPLETVV 122 Query: 135 SRQVSALMDVMRNNRASDRALAAAEGAPEHVINFVSKMSRAATLASQQSGVPARLIMGQA 194 Q AL +++ + + P F++++S A LASQQSGVP LI+ QA Sbjct: 123 RYQNQALSQLVQKAVPRN----YDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQA 178 Query: 195 ALESGWGQREIKHEDGRTSYNLFGIKAGPSWKGKVVNVLTTEYEDGVAKKVTQPFRAYSS 254 ALESGWGQR+I+ E+G SYNLFG+KA +WKG V + TTEYE+G AKKV FR YSS Sbjct: 179 ALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSS 238 Query: 255 YEESFADYARLIGNSPRYEAVTQARNEIEAARRIQSAGYATDPQYAQKLIGVMSQLRGAA 314 Y E+ +DY L+ +PRY AVT A + + A+ +Q AGYATDP YA+KL ++ Q++ + Sbjct: 239 YLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSIS 298 Query: 315 AKVDISRQM 323 KV + M Sbjct: 299 DKVSKTYSM 307
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 327 bits (840), Expect = e-108 Identities = 208/556 (37%), Positives = 319/556 (57%), Gaps = 21/556 (3%) Query: 7 ALGGLNASQAGLATTGHNINNATTVGYNRQRVMISTAGAQATTNGYIGRGVQVDTVVRSY 66 A+ GLNA+QA L T +NI++ GY RQ +++ A + G++G GV V V R Y Sbjct: 7 AMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGVQREY 66 Query: 67 DSFLYKQLVGAQGSGAQLQAQLDQVSQVNNLFADRTVGIAPGLTNFFTSMNTVASKPADP 126 D+F+ QL AQ + L A+ +Q+S+++N+ + T +A + +FFTS+ T+ S DP Sbjct: 67 DAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLVSNAEDP 126 Query: 127 AARQDLLGKANSLTTQIRSAYQEMQNQRLGLNTQITTTVEQVNSYLTRINDLNSQISTAR 186 AARQ L+GK+ L Q ++ Q +++Q +N I +V+Q+N+Y +I LN QIS Sbjct: 127 AARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLNDQISRLT 186 Query: 187 AKAGGNPPNDLLDQRDQAVSELNQLIGVT-TYEQGDKLSISLASGGQALLSGDTVYPLQA 245 G PN+LLDQRDQ VSELNQ++GV + + G +I++A+ G +L+ G T L A Sbjct: 187 GVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMAN-GYSLVQGSTARQLAA 245 Query: 246 VSSAKDVSRTVIAYTLPAGSGGKTVAVELNDAEVTGGKLGGLLQFRATSLDFMQAQLGQM 305 V S+ D SRT +AY G +E+ + + G LGG+L FR+ LD + LGQ+ Sbjct: 246 VPSSADPSRTTVAYV-----DGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 300 Query: 306 AVGLALSFNEQHRQGLDTAGNPGTDFFSIGKPQGVPNAGNKSGAQISGEFTNVNNINAKD 365 A+ A +FN QH+ G D G+ G DFF+IGKP + N NK I T+ + + A D Sbjct: 301 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD 360 Query: 366 YEISFDGTNYMVTRLPEGTQVYNGPATGTPPTATLDLN---AEMGVTLTIDSPPQAGDKW 422 Y+ISFD + VTR A+ T T T D N A G+ LT P D + Sbjct: 361 YKISFDNNQWQVTR----------LASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSF 410 Query: 423 ALSPTRDAARDIKVIITDPEKVAAADTE-GGDANGKNALKLAQLQNTKVLGHGTMSITEM 481 L P DA ++ V+ITD K+A A E GD++ +N L LQ+ G S + Sbjct: 411 TLKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDA 470 Query: 482 FGQVVNTVGVQTAQIQSANTAQKNLIAQKTAAQQAVSGVNLNEEYVSLSLYQEQYQASAR 541 + +V+ +G +TA +++++ Q N++ Q + QQ++SGVNL+EEY +L +Q+ Y A+A+ Sbjct: 471 YASLVSDIGNKTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQ 530 Query: 542 IIDVASTLFDTLLGLR 557 ++ A+ +FD L+ +R Sbjct: 531 VLQTANAIFDALINIR 546
>FLAGELLIN#Flagellin signature. Length = 507 Score = 43.9 bits (103), Expect = 9e-07 Identities = 60/363 (16%), Positives = 120/363 (33%), Gaps = 23/363 (6%) Query: 1 MRLSTSMMYSNGLKGVLAQESDMNRLVEQVGSGKKFLTPADDPLSASLAINVAQTQSMNS 60 ++T+ + + +S ++ +E++ SG + + DD +A AI T ++ Sbjct: 2 QVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDD--AAGQAIANRFTSNIKG 59 Query: 61 TYQLNRNT--AKTNLGQENNVLDSITTALADVRTRVVQAGNGTFADSDRQALSTALKNAR 118 Q +RN + L+ I L VR VQA NGT +DSD +++ ++ Sbjct: 60 LTQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRL 119 Query: 119 DALLGLANSTDGNGQYLFSGYQGGVVPYSQDTNGKI------VYSGATGERTVQVDQSRQ 172 + + ++N T NG + S + + I + + G V+ ++ Sbjct: 120 EEIDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 173 MSTSDIGSDIFNRANPGSQAYVSTAAQANTGTAQFSTVSVTPGSPNIGKDFRLQFESDPA 232 + D+ S N + A + + + + T + P D Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTV------------PDKV 227 Query: 233 TGNMGYRVITTDPNANPPVPPVTTPAPPAAPTVYTPDAAIDFGGVSVVIKGTPQNGDVID 292 N +TTD N + A T A G G Sbjct: 228 YVNAANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFD-YKGVTFT 286 Query: 293 VQSVQSADVDMFNTLDSLIKTLDSPIAGDPVALAKLNNELATANKKLSTNYDNVQTVAAS 352 + + D + + + + +A A ++ ++K + T+ N Q Sbjct: 287 IDTKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDD 346 Query: 353 VGA 355 Sbjct: 347 KTK 349
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 33.4 bits (76), Expect = 0.002 Identities = 26/122 (21%), Positives = 35/122 (28%), Gaps = 10/122 (8%) Query: 518 DVIEVPARQLAQQHSAPRVAAAQTE----AQVSAARTAKPAAQAAAKPEPAAEP----DH 569 VIE+PA AQ S VA A E Q +P + PEP E + Sbjct: 39 QVIELPAP--AQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEK 96 Query: 570 SPVTPPAAPAPRLAQPVRARPTANSGATAARPLRRPVVKTTDATDVKPVKPAPPAARRAP 629 P P P R + A P ++ P + + Sbjct: 97 PKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASG 156 Query: 630 PA 631 P Sbjct: 157 PR 158 Score = 31.1 bits (70), Expect = 0.009 Identities = 18/99 (18%), Positives = 27/99 (27%), Gaps = 1/99 (1%) Query: 534 PRVAAAQTEAQVSAARTAKPAAQAAAKPEPAAEPDHSPVTPPAAPAPRLAQPVRARPTAN 593 P A + V+ A P A PEP EP+ P P P + +P Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQP-PPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPK 102 Query: 594 SGATAARPLRRPVVKTTDATDVKPVKPAPPAARRAPPAD 632 + + +P A R + Sbjct: 103 PKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSST 141
>PF05272#Virulence-associated E family protein Length = 892 Score = 35.4 bits (81), Expect = 7e-04 Identities = 13/54 (24%), Positives = 18/54 (33%) Query: 510 ARLTHSAPRAKTATAEAASAARPPRRPAPRAAANDAKPAPAATRRQAPADDDWE 563 AR + + TA A A PP++ P A A P +W Sbjct: 380 ARALLADVSSPTAAAGGAGGGEPPKKRDPSAGAGTDPGGPGGGDDGEDPFGEWL 433
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 167 bits (425), Expect = 3e-53 Identities = 121/252 (48%), Positives = 179/252 (71%), Gaps = 1/252 (0%) Query: 1 MFSFTIEQLNGWIGQFLWPFVRILALVGTAPLFSESTVPVKVKIGLAFVLAVAVSPALDP 60 M T EQ W+ + WP +R+LAL+ TAP+ SE +VP +VK+GLA ++ A++P+L P Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSL-P 59 Query: 61 APPIAPGSFAGLWMVMQQVLIGIAMGFTMRLVFAAVQTAGEFVGLQMGLSFASFFDPSTG 120 A + SF LW+ +QQ+LIGIA+GFTM+ FAAV+TAGE +GLQMGLSFA+F DP++ Sbjct: 60 ANDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASH 119 Query: 121 ANTAVLSRLFNIVAMLTFLALDGHLLVLAALVRSFDTLPVAAIQLHQNGWGVVVEWGKTV 180 N VL+R+ +++A+L FL +GHL +++ LV +F TLP+ L+ N + + + G + Sbjct: 120 LNMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLI 179 Query: 181 FVSGLLLALPLICALLTINLAMGILNRAAPQLSVFSVGFPVSLIVGVVLLTVVLPNSGPF 240 F++GL+LALPLI LLT+NLA+G+LNR APQLS+F +GFP++L VG+ L+ ++P PF Sbjct: 180 FLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPF 239 Query: 241 LESLFESGLSAM 252 E LF + + Sbjct: 240 CEHLFSEIFNLL 251
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 60.2 bits (146), Expect = 8e-16 Identities = 26/78 (33%), Positives = 46/78 (58%) Query: 4 ETVMTMTYQAMKIALAMAGPLLVITLIVGLVISIFQAATQINEMTLSFIPKLLAMCGVLV 63 + ++ +A+ + L ++G ++ I+GL++ +FQ TQ+ E TL F KLL +C L Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 LLGPWLIGIMVDYIRQLI 81 LL W +++ Y RQ+I Sbjct: 62 LLSGWYGEVLLSYGRQVI 79
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 287 bits (735), Expect = e-100 Identities = 162/239 (67%), Positives = 190/239 (79%), Gaps = 2/239 (0%) Query: 21 ALLGLALFPAGVVAQATLPALTATPGPGGSETYSLSMQTLLLMTSLSFLPAALLMMTGFT 80 A + L L AQ LP +T+ P PGG +++SL +QTL+ +TSL+F+PA LLMMT FT Sbjct: 8 APVLLWLITPLAFAQ--LPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMMTSFT 65 Query: 81 RIIIVLGLLRSAMGTAMSPPNHVLIGLALFLTFYTMSPVFDKIYTDAYKPLSEGSIQFEA 140 RIIIV GLLR+A+GT +PPN VL+GLALFLTF+ MSPV DKIY DAY+P SE I + Sbjct: 66 RIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISMQE 125 Query: 141 AVERAAGPLRTFMLHQTRENDLALFANLAKQPALEDPSQVPLRILVPAFITSELKTAFQI 200 A+E+ A PLR FML QTRE DL LFA LA L+ P VP+RIL+PA++TSELKTAFQI Sbjct: 126 ALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELKTAFQI 185 Query: 201 GFTIFIPFLIIDLVVASVLMALGMMMVPPVTVALPFKLMLFVLADGWNLLMGSLAQSFY 259 GFTIFIPFLIIDLV+ASVLMALGMMMVPP T+ALPFKLMLFVL DGW LL+GSLAQSFY Sbjct: 186 GFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLAQSFY 244
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 143 bits (361), Expect = 2e-46 Identities = 89/157 (56%), Positives = 105/157 (66%), Gaps = 28/157 (17%) Query: 28 NPPTQADGLKPAQDD-WAAAMAEQTAATPPATAAPAPAAAAPAAPAPAAPAAQSAAQSVF 86 NP + G A DD WA A+ EQ A T +SAA +VF Sbjct: 6 NPSDENTG---ALDDLWADALNEQKATT-----------------------TKSAADAVF 39 Query: 87 KPLAGSA-AGNGTDIDLIMDVPVQLTVELGRTRLTIKNLLQLGQGSVVELDGLAGEPMDI 145 + L G +G DIDLIMD+PV+LTVELGRTR+TIK LL+L QGSVV LDGLAGEP+DI Sbjct: 40 QQLGGGDVSGAMQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDI 99 Query: 146 FVNGYLIAQGEVVVVEDKYGIRLTDIITPSERINRLN 182 +NGYLIAQGEVVVV DKYG+R+TDIITPSER+ RL+ Sbjct: 100 LINGYLIAQGEVVVVADKYGVRITDIITPSERMRRLS 136
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 272 bits (697), Expect = 4e-92 Identities = 85/282 (30%), Positives = 147/282 (52%), Gaps = 5/282 (1%) Query: 7 LSQDEVDALLAGV-TGESDSK-KESAGPNDGARAYDLSSPDRVVRRRMQTLELINERFAR 64 LSQDE+D LL + +G++ + YD PD+ + +M+TL L++E FAR Sbjct: 5 LSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHETFAR 64 Query: 65 QMRSVLLNFMRRSADITVGSIKIQKYADFERNLPVPSNLNMVQMKPLRGTALFTYDPNLV 124 + L +R + V S+ Y +F R++P PS L ++ M PL+G A+ DP++ Sbjct: 65 LTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVDPSIT 124 Query: 125 FLVIDSLFGGDGRYHTRVEGRDFTTTEQRIIRRLLNLTLESYGKSWDPVYPIEFDYVRSE 184 F +ID LFGG G+ RD T E ++ ++ L + +SW V + + E Sbjct: 125 FSIIDRLFGGTGQAAKVQ--RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRLGQIE 182 Query: 185 MHTKFASITGNNEVVVVTSFHIEFGATGGDLNICLPYSMIEPVRDLL-TRPLQETTLEEV 243 + +FA I +E+VV+ + + G G +N C+PY IEP+ L ++ + Sbjct: 183 TNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVRRSS 242 Query: 244 DQRWSQQLSRQVRSADIDVVAEFARIPSSIRELMRMKVGDIL 285 ++ L ++ + D+DVVAE + S+R+++ ++VGDI+ Sbjct: 243 TTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDII 284
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 28.3 bits (63), Expect = 0.025 Identities = 15/59 (25%), Positives = 22/59 (37%), Gaps = 13/59 (22%) Query: 123 LEEGKVVIFAAGTGNPFFTT-------------DTAAALRGAEIGAEIVLKATKVDGIY 168 +E G +VI + G G P D A E+ A+I + T V+G Sbjct: 183 VERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAA 241
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 46.0 bits (109), Expect = 2e-07 Identities = 26/132 (19%), Positives = 54/132 (40%), Gaps = 1/132 (0%) Query: 26 LPNVATDLDVSIDIAGLLITGYAMGVVIGAPIMAIITARLPRKATLIGLASTFVLGNLLC 85 LP++A D + + T + + IG + ++ +L K L+ G+++ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 86 ALAPGYGT-LMAARVFTAFCHGAFFGIGAVVAADLVPRHQRSSAIALMFTGLTLANVLGV 144 + + + L+ AR AF + VV A +P+ R A L+ + + + +G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 145 PLGTALGQVAGW 156 +G + W Sbjct: 157 AIGGMIAHYIHW 168
>RTXTOXINC#Gram-negative bacterial RTX toxin-activating protein C signature. Length = 170 Score = 27.9 bits (62), Expect = 0.029 Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 9/50 (18%) Query: 152 PVHPDWIVTPLMAENMGPVMAPSLLPAFQAGDYVALSSRTRPRAWDDWLN 201 P+H +W V+ L A N +LPA QA YV L+ P A+ W N Sbjct: 21 PLHRNWPVS-LFAIN--------VLPAIQANQYVLLTRDDYPVAYCSWAN 61
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 32.2 bits (73), Expect = 0.002 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 3/55 (5%) Query: 73 LEVVSQDRESELASVRAALELDV-DCL-LGGTHVDEALALLAGSRIRYYPFPGRV 125 ++VV++ L SVR L L V D + L THV + L G+R ++ PG V Sbjct: 259 MDVVAEVGSLRL-SVRDILGLRVGDIIRLHDTHVGDPFVLSIGNRKKFLCQPGVV 312
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 33.8 bits (77), Expect = 0.001 Identities = 14/94 (14%), Positives = 25/94 (26%), Gaps = 2/94 (2%) Query: 317 PPAAQAPAQSQSRPPQ--SQSPGQPQSRPSQSPNQPQARPQQAQPQARPQQASRPGPAPD 374 PA P Q+ PP+ + +P+ P P + + + P Sbjct: 56 APADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPK 115 Query: 375 NLAQGAPREHRAAPANRPEARPQGNPQHGGGRAA 408 + + N ARP + Sbjct: 116 RDVKPVESRPASPFENTAPARPTSSTATAATSKP 149 Score = 29.2 bits (65), Expect = 0.032 Identities = 13/96 (13%), Positives = 24/96 (25%), Gaps = 15/96 (15%) Query: 317 PPAAQAPAQSQSRP----------PQSQSPGQPQSRPSQSPNQPQARP-----QQAQPQA 361 P A Q P + P P+ + +P P + + +P Sbjct: 63 PQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVE 122 Query: 362 RPQQASRPGPAPDNLAQGAPREHRAAPANRPEARPQ 397 + AP + P + P+ Sbjct: 123 SRPASPFENTAPARPTSSTATAATSKPVTSVASGPR 158
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 44.9 bits (106), Expect = 2e-07 Identities = 39/176 (22%), Positives = 72/176 (40%), Gaps = 8/176 (4%) Query: 208 AMTRERERGTMENLLAMPVRPLEVMTGKIVPYIAIGLIQSTIILLAAYFVFHVPF---LG 264 A R + T E +L +R +++ G++ + I + A + + + L Sbjct: 90 AFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGYTQWLSLLY 149 Query: 265 SLVTVYLGALIFVAANLTVGITLSSLAQNQLQAMQLTMFYFLPNMLLSGFMFPFLGMPKW 324 +L + L L F + + V ++LA + + P + LSG +FP +P Sbjct: 150 ALPVIALTGLAFASLGMVV----TALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIV 205 Query: 325 AQYLGNLLPLTHFNRLIRGILLKGNGWWDLWPAIWPMLLFTVVVMTAAVKFYRRTL 380 Q LPL+H LIR I+L D+ + + ++ V+ + RR L Sbjct: 206 FQTAARFLPLSHSIDLIRPIMLGHPV-VDVCQHVGALCIYIVIPFFLSTALLRRRL 260
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 52.9 bits (127), Expect = 7e-10 Identities = 49/360 (13%), Positives = 104/360 (28%), Gaps = 91/360 (25%) Query: 43 IASSEAGRLDTLSVRRGQQVAAAAPLFALEAERETAARDQAGAQLAAASAQLEDIATGKR 102 I E + + V+ G+ V L L A A + + L A + R Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 103 PPEVD---------------------------------VARAQLAQAEAASRRSAAQLAR 129 E++ + Q Q E + A+ Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218 Query: 130 DTAQFRA----GGVARAQLDDSRE------------------------QAQSDAARVREL 161 A+ V +++LDD + + +++ ++ Sbjct: 219 VLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQI 278 Query: 162 RAQLEVANLPGRQ----------DQRRAQAAQVDAARATLAQADWALAQKRLAAPAAALV 211 +++ A + D+ R + LA+ + + AP + V Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKV 338 Query: 212 FD-TLYRVGEWVPAGSPVVSLLPPGN-IKVRFFVPETVVGTLKPGQQAMVRCDGCGD--- 266 ++ G V ++ ++P + ++V V +G + GQ A+++ + Sbjct: 339 QQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRY 398 Query: 267 -PVPVRIDYISPQAEYTPPVIYSRETRGKLVYMVEAR------PAPDAATRLHPGQPVEA 319 + ++ I+ A + R LV+ V + L G V A Sbjct: 399 GYLVGKVKNINLDA--------IEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTA 450
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.5 bits (87), Expect = 2e-04 Identities = 23/188 (12%), Positives = 51/188 (27%), Gaps = 21/188 (11%) Query: 479 ALKRELAQMQAASAALLARLGVAHAAEAEE------RHARGIALQRELDAMRKTLAIHAP 532 L R + + L + +E E + Q + L Sbjct: 155 ILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKR- 213 Query: 533 KGVDALRGQRNEAQARRAQLAERLALLPPAAEADDVDPPAARQALRDAEASAAQAEQALA 592 + + N + RL + A+ A+ + E +A L Sbjct: 214 AERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAI----AKHAVLEQENKYVEAVNELR 269 Query: 593 AVQRALDADGARAQLLETQAAARGADLQSPERAAQ-RQDRAGRLAEARNGHDLLEQRLHQ 651 ++QL + ++ A + + + +L + + LL L + Sbjct: 270 V---------YKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAK 320 Query: 652 AQAALEAL 659 + +A Sbjct: 321 NEERQQAS 328 Score = 30.2 bits (68), Expect = 0.040 Identities = 31/213 (14%), Positives = 64/213 (30%), Gaps = 20/213 (9%) Query: 494 LLARLGVAHAAEAEERHARGIALQRELDAMRKTLAIHAPKGVDALRGQRNEAQARRAQLA 553 +L +L A AEA+ + LQ L+ R L + +L Sbjct: 123 VLLKL-TALGAEADTLKTQSSLLQARLEQTRY----------QILSRSIELNKLPELKLP 171 Query: 554 ERLALLPPAAEADDVDPPAARQALRDAEASAAQAEQALAAVQRALDADGARAQLLETQAA 613 + + E ++ + Q E L + AR E + Sbjct: 172 DEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSR 231 Query: 614 ARGADLQSPERAAQRQ--------DRAGRLAEARNGHDLLEQRLHQAQAALEALRPELLE 665 + L +Q ++ + EA N + + +L Q ++ + + + E + Sbjct: 232 VEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEE-YQ 290 Query: 666 QDAQRYEKSAAIERDAQHRRHSEIQQLLGKLEQ 698 Q ++ + + L K E+ Sbjct: 291 LVTQLFKNEILDKLRQTTDNIGLLTLELAKNEE 323
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.002 Identities = 18/165 (10%), Positives = 41/165 (24%), Gaps = 10/165 (6%) Query: 16 FMLLAAPLAARAAQLSPADSHFLQAAAAADAFQLQAARLASERAASTEVRAFAEKMRSSY 75 F ++ R L F +L + +ER E + Sbjct: 176 FQNVSEEEVLRLTSL--IKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 76 QERDAGLRQLARAKRITLPAKAEPGDQRA-----LEAMAGKTGEAFDSLYIEQVALQAHE 130 + R L + I A E ++ L + + I + Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESE--ILSAKEEYQL 291 Query: 131 KSERLYRTAAEQSADAQVRDFALRHQPVLADQLALARALKRDPAA 175 ++ ++ L + ++ ++ R P + Sbjct: 292 VTQLFKNEILDKLRQTTDNIGLLTLELAKNEER-QQASVIRAPVS 335
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 97.0 bits (241), Expect = 7e-26 Identities = 71/237 (29%), Positives = 111/237 (46%), Gaps = 13/237 (5%) Query: 50 LAGMAAIVTGGDSGIGRAVSVLFAREGADVAIVYLNEHEDARETERAVQAEGRRCLLIAG 109 + G A +TG GIG AV+ A +GA +A V N E + +++AE R Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNP-EKLEKVVSSLKAEARHAEAFPA 64 Query: 110 DVRESAFCDRAVEQAAQAFGRLDVLVNNAAYQQHDEGLSAISDEKWDKTLRTNIYGYFYM 169 DVR+SA D + + G +D+LVN A + ++SDE+W+ T N G F Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVN-VAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 170 ARAILPHLRA--GAAIINTGSVTGLRGSGGLLDYSTSKGAIHAFTRSLASNLASQGIRVN 227 +R++ ++ +I+ GS + Y++SK A FT+ L LA IR N Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 228 AVAPGPVWTPLNP---ADRDADE--IPSFGQDTELGRP----AQPEEISPAYVFLAA 275 V+PG T + AD + E I + + G P A+P +I+ A +FL + Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 26.9 bits (59), Expect = 0.003 Identities = 11/37 (29%), Positives = 13/37 (35%) Query: 10 PPKPEPIPPGSPPGDLPVDPDTDEPEVDLPPLEPPPA 46 PP P+P P P P P + P P A Sbjct: 572 PPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELSA 608
>PF06580#Sensor histidine kinase Length = 349 Score = 23.7 bits (51), Expect = 0.043 Identities = 8/44 (18%), Positives = 21/44 (47%) Query: 1 MSTILLIVLILLLIGAVPAWPYSRGWGYYPSGLLGIVLIVLIVL 44 + I + ++ L+L A ++ +GW G + + ++ V+ Sbjct: 43 IFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQIILRVLPACVV 86
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 52.1 bits (125), Expect = 2e-09 Identities = 57/284 (20%), Positives = 97/284 (34%), Gaps = 16/284 (5%) Query: 17 LLMGLVTLTPMGIDIYLPSLPAMAAGFEQPMSALQASITLFIFAVGVGQVLIGP----LA 72 +++ V L +GI + +P LP + + + A + + + Q P L+ Sbjct: 9 VILSTVALDAVGIGLIMPVLPGLLRDL-VHSNDVTAHYGILLALYALMQFACAPVLGALS 67 Query: 73 DRYGRRPVALGGALAYLLGSALGAAATSLELFYAARVIQGLGACSASLVAFAAVRDRFSP 132 DR+GRRPV L + A+ A A L + Y R++ G+ + + VA A + D Sbjct: 68 DRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGA-VAGAYIADITDG 126 Query: 133 AVGARVYSYLNGALCTVPALAPMLGGALAVHLGWRSTFVFMVLFALALALLLAWRFDETR 192 AR + +++ P+LGG + + F L + E+ Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLMG-GFSPHAPFFAAAALNGLNFLTGCFLLPESH 185 Query: 193 AAPPAGRAPLYSLRRYAPIITSGRFLYFAVFGMAGMAMILVFVSAAPVVLVQQLGYSELG 252 R PL V + + I+ V P L G Sbjct: 186 ---KGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFH 242 Query: 253 FSA------WFGGNAAINIAAFFLAPVFIARFGRHAMLRVGMAA 290 + A ++A + AR G L +GM A Sbjct: 243 WDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIA 286
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 175 bits (446), Expect = 1e-59 Identities = 67/140 (47%), Positives = 89/140 (63%), Gaps = 6/140 (4%) Query: 16 RRQRGFTLIEIMVVIVIMGILAALIVPRLLDRPDQARAVAARQDISALMQALKLYRLDNG 75 +QRGFTL+EIMVVIVI+G+LA+L+VP L+ ++A A DI AL AL +Y+LDN Sbjct: 5 DKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNH 64 Query: 76 SYPNTEQGLRALVERPASGPGASSAWRA--YLDRLPNDPWGHPYQYLNPGTRGEIDVFSL 133 YP T QGL +LVE P P A++ + Y+ RLP DPWG+ Y +NPG G D+ S Sbjct: 65 HYPTTNQGLESLVEAPTLPPLAAN-YNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLLSA 123 Query: 134 GADGKPDGDAGNADIGSWQL 153 G DG+ + DI +W L Sbjct: 124 GPDGEMGTE---DDITNWGL 140
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 352 bits (904), Expect = e-121 Identities = 168/406 (41%), Positives = 246/406 (60%), Gaps = 5/406 (1%) Query: 1 MADFRFEAADALGRIQRGVLSADSARAARAQLRAQGLTALAV---RLSARRGAGSGELFA 57 MA + ++A DA G+ RG ADSAR AR LR +GL L+V R ++ +G Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 58 --ARLSDSDLAWATRQLASLLAAGLPLEGALSATVEQAEKKHIAATFSGVRADVRGGQRF 115 RLS SDLA TRQLA+L+AA +PLE AL A +Q+EK H++ + VR+ V G Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 116 SDALSARPRDFPPIYRALIKAGEDSGDLARIMERLADYIEGRNALRSKVLTAFIYPAIVG 175 +DA+ P F +Y A++ AGE SG L ++ RLADY E R +RS++ A IYP ++ Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 176 VVSICIVVFLLAYVVPQVVSAFSQARQELPWITRAMLAASDYVRAWGGLNALVAALLFGL 235 VV+I +V LL+ VVP+VV F +Q LP TR ++ SD VR +G L F Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 236 WRLSQRAEAARLAWHGRILRLPMIGRFALGVNTARFAATLAILADAGVPLLRALDAARQT 295 +R+ R E R+++H R+L LP+IGR A G+NTAR+A TL+IL + VPLL+A+ + Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 296 LANDCLRRAVLDATERIEGGSGLGAALRQQKVFPPLLCHLVASGEKTGTLARMLDRAAQT 355 ++ND R + AT+ + G L AL Q +FPP++ H++ASGE++G L ML+RAA Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 356 LSADIERRAMAMTAMLEPLMILIMGGVVLTIVLAVMLPIMEINQMV 401 + + + EPL+++ M VVL IVLA++ PI+++N ++ Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>PF05860#haemagglutination activity domain. Length = 117 Score = 62.1 bits (151), Expect = 5e-13 Identities = 18/93 (19%), Positives = 39/93 (41%), Gaps = 4/93 (4%) Query: 136 TVVTVDQTADKAILNWETFNVGRNTTVSFKQQASSWSVLNRVNDPRARPSQIQGQIEAPG 195 + Q +++ F+V + T F + ++++RV S I G I A Sbjct: 23 IIERGTQAGSNLFHSFQEFSVPTSGTAFFNNPTNIQNIISRVTGGS--VSNIDGLIRANA 80 Query: 196 T--VMIVNRNGIVFSGSSQVNTRNLVAAAVGMS 226 T + ++N NGI+F +++++ + Sbjct: 81 TANLFLINPNGIIFGQNARLDIGGSFVGSTANR 113
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 29.6 bits (66), Expect = 0.008 Identities = 10/46 (21%), Positives = 24/46 (52%) Query: 131 RAAISFEVSPMGRVERARVLGSTGDRAKDDEIVLALDQAVFDKAPP 176 + + F+V+P GRV+ ++L + + E+ A+ + ++ P Sbjct: 175 QVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKP 220
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 46.9 bits (111), Expect = 4e-09 Identities = 18/73 (24%), Positives = 34/73 (46%) Query: 24 QRGFTLIELMVVLVIVGVATAALGLSIRSDPARQLRDDAQRLVERLAAAQSEVRIDGRAI 83 QRGFTL+E+M++L+++GV+ + L+ + R +L Q G+ Sbjct: 3 QRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQFF 62 Query: 84 AWQADADGYRFVR 96 D ++F+ Sbjct: 63 GVSVHPDRWQFLV 75
>PilS_PF08805#PilS N terminal Length = 185 Score = 31.1 bits (70), Expect = 0.001 Identities = 10/38 (26%), Positives = 20/38 (52%) Query: 18 AGFTLLEILIALAIVSVALAAVMRTTGMLTTNNGVLRE 55 G TL+E+L+ + ++ V A+ + M+ +N E Sbjct: 26 KGATLMEVLLVVGVIVVLAASAYKLYSMVQSNIQSSNE 63
>PF05946#Toxin-coregulated pilus subunit TcpA Length = 199 Score = 32.2 bits (73), Expect = 0.001 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 10/73 (13%) Query: 10 TLIEVVIAIMIMAVIS----LISWRAIDSVALTSRRLDQHTEEALALQRAFDQFERDIGA 65 TL+EV+I + IM V+S ++ RAIDS +T ++ +Q A Q R +G Sbjct: 2 TLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQSLNS-----IQVALTQTYRGLG- 55 Query: 66 RSPDLAESAAPAA 78 P A++ A + Sbjct: 56 NYPATADATAASK 68
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.9 bits (168), Expect = 8e-17 Identities = 35/199 (17%), Positives = 65/199 (32%), Gaps = 10/199 (5%) Query: 1 MPSDTALPSPDTRQRLLQATERLVYAGGIHATGMDLIVRTSGVARKQVYRLYPNKDALVA 60 M T + +TRQ +L RL G+ +T + I + +GV R +Y + +K L + Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 AALRARDERWMQWFVAASSR-----AQAPRARLLAMFDALREWFGTDDFRGCAF--LNAA 113 + + + ++ R L+ + ++ F Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 114 GEIGDEASPILAVAREHKARLLEYVRTLTRAAALP---DPDEAAAQLLVLIDGAIAVALV 170 GE+ + E R+ + ++ A LP AA + I G + L Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 171 TRDPAIADSAGRAAAALLG 189 R A+L Sbjct: 181 APQSFDLKKEARDYVAILL 199
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 27.3 bits (60), Expect = 0.020 Identities = 16/69 (23%), Positives = 33/69 (47%), Gaps = 6/69 (8%) Query: 14 TVGEVARRSGVPVSTIHFY-ESKGLIHSSRSDGNQRRFPGIVLRYIAIIKVAQRTGIPLE 72 ++GE+A+ +GV I+++ + K + S + ++ + L Y A+ G PL Sbjct: 33 SLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQ-----AKFPGDPLS 87 Query: 73 EIREAMARF 81 +RE + Sbjct: 88 VLREILIHV 96
>cloacin#Cloacin signature. Length = 551 Score = 26.6 bits (58), Expect = 0.018 Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 1/77 (1%) Query: 3 GGGHGTDSGAGLHGGSRAAGIAGAFADRLALAATPVFALMAL-LAAMREAGAMAALCGAG 61 GG +SG G G + +A A +TP +A+ ++A + A+A + A Sbjct: 64 NGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIADIMAAL 123 Query: 62 AWPFDGMAWMYALMSVF 78 PF W AL V Sbjct: 124 KGPFKFGLWGVALYGVL 140
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.5 bits (87), Expect = 7e-05 Identities = 30/204 (14%), Positives = 61/204 (29%), Gaps = 8/204 (3%) Query: 98 REDAQRAEDQRLADLAAQLARREALLASRERDLEEALKVATGQLAATEARLRTAESQLRQ 157 D + + L + R + L S E + LK+ E + + Sbjct: 133 EADTLKTQSS-LLQARLEQTRYQILSRSIELNKLPELKLPD------EPYFQNVSEEEVL 185 Query: 158 RDEALAHGQQQLADARAALLAQVADAERGRQEQAEALAAAHARHTAHERRWLNDLDAERG 217 R +L Q + D +R + A + + E+ L+D + Sbjct: 186 RLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLH 245 Query: 218 NAKRLQARLEDLLAARQQQAEQSRQALAQAAERLHAAEAEAAERLRVAESEAAAQLRAAQ 277 + + + + + R +Q + + + A E ++ ++ Sbjct: 246 KQAIAKHAVLEQENKYVEAVNELRVYKSQLEQ-IESEILSAKEEYQLVTQLFKNEILDKL 304 Query: 278 AEAQAEQGRRLAELATVREALQAS 301 + G ELA E QAS Sbjct: 305 RQTTDNIGLLTLELAKNEERQQAS 328 Score = 30.6 bits (69), Expect = 0.009 Identities = 21/144 (14%), Positives = 42/144 (29%), Gaps = 10/144 (6%) Query: 200 RHTAHERRWLNDLDAERGNAKRLQARLEDLLAARQQQAEQSRQALAQAAERLHAAEAEAA 259 A + + L R R Q + + + + + Q E Sbjct: 131 GAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVS------EEEV 184 Query: 260 ERLRVAESEAAAQLRAAQAEAQAEQGRRLAELATVREALQASRRREQELAQRLAAAEAQQ 319 RL E + + + + + ++ AE TV + + RL + Sbjct: 185 LRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSS-- 242 Query: 320 AELMAQQKARDAQLLELTRHLISA 343 L+ +Q +LE + A Sbjct: 243 --LLHKQAIAKHAVLEQENKYVEA 264 Score = 30.6 bits (69), Expect = 0.011 Identities = 25/131 (19%), Positives = 43/131 (32%), Gaps = 7/131 (5%) Query: 73 AQAAAHFWEAALSAARADLAGAN---REREDAQRAEDQRLADLAAQLARREALLASRERD 129 Q + E L RA+ E+ R E RL D + L ++A+ + Sbjct: 198 WQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFS-SLLHKQAIAKHAVLE 256 Query: 130 LEEALKVATGQLAATEARLRTAESQLRQRDEALAHGQQQLADARAALLAQVADAERGRQE 189 E A +L +++L ES++ E Q + +L ++ Sbjct: 257 QENKYVEAVNELRVYKSQLEQIESEILSAKEEY---QLVTQLFKNEILDKLRQTTDNIGL 313 Query: 190 QAEALAAAHAR 200 LA R Sbjct: 314 LTLELAKNEER 324 Score = 29.8 bits (67), Expect = 0.018 Identities = 22/166 (13%), Positives = 52/166 (31%), Gaps = 11/166 (6%) Query: 171 DARAALLAQVADAERGRQEQAEALAAAHARHTAHERRWLNDLDAERGNAKRLQARLEDLL 230 A A L + + R EQ + + L E + + L Sbjct: 131 GAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPE--LKLPDEPYFQNVSEEEVLRLT 188 Query: 231 AARQQQAEQSRQALAQAAERLHAAEAEAAERLRVAESEAAAQLRAAQAEAQAEQGRRLAE 290 + ++Q + Q L AE A++ + ++ E+ RL + Sbjct: 189 SLIKEQFSTWQNQKYQKELNLDKKRAERL--------TVLARINRYENLSRVEK-SRLDD 239 Query: 291 LATVREALQASRRREQELAQRLAAAEAQQAELMAQQKARDAQLLEL 336 +++ ++ E + A + +Q + ++++L Sbjct: 240 FSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSA 285
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 25.9 bits (57), Expect = 0.018 Identities = 14/58 (24%), Positives = 28/58 (48%), Gaps = 9/58 (15%) Query: 1 MANAALILGPALPDAGWDYVRVLLLKIALALAMTGLALANRYRWIARIRAEPALALHA 58 ++N+A L P+A +D+VR + + G + + ++R IA P + L + Sbjct: 189 LSNSAATL--WHPEAHFDWVRP-------GIILYGASPSGQWRDIANTGLRPVMTLSS 237
>PF04183#IucA / IucC family Length = 580 Score = 545 bits (1405), Expect = 0.0 Identities = 160/562 (28%), Positives = 274/562 (48%), Gaps = 20/562 (3%) Query: 16 PEVWDKVNRLLVKKAISEYAHEWLLEPERLGPAEAPGFDRYRLVLADGHAEYQFDAQLMA 75 + WD VNR LV K +SE +E + E G DRY + L A+++F A+ Sbjct: 3 HKDWDLVNRRLVAKMLSELEYEQVFHAESQGD------DRYCINLPG--AQWRFIAERGI 54 Query: 76 MRHWRIPPESISKTMAGTPAPLDALQFVIEIRDKLGMPEDRLPIYLDEITSTLHGSAYKH 135 I +++ P+ A +++++ L M + + ++ ++ +TL G Sbjct: 55 WGWLWIDAQTLRCA----DEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLL 110 Query: 136 -TRGAPAAAELALADYQTIETSMIEGHPSFVANNGRLGFNAEDYHVYAPECASPIRVMWL 194 R +A++L + ++ ++ GHP FV N GR G+ E YAPE A+ R+ WL Sbjct: 111 KARRGLSASDLINLNADRLQ-CLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWL 169 Query: 195 AVHKDNAHFACLSTMDYDSLLRDELGADTVARHTQTLRDQGLDPADYYFMPSHPWQWFNK 254 AV +++ + C + MD LL + AR +Q ++ GLD ++ +P HPWQW K Sbjct: 170 AVKREHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLDH-NWLPLPVHPWQWQQK 228 Query: 255 LSLAFAPYVATRKIVCLGYGDDDYLAQQSIRTFYNISQPGKHYVKTSLSILNMGFMRGLS 314 ++ F A ++V LG D +LAQQS+RT N S+ G +K L+I N RG+ Sbjct: 229 IATDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIP 288 Query: 315 PYYMSGTPAINEYLHGLISSDPWLRRNGFTILREAASLGFRNYYYEAAISVDTPYKKMFS 374 Y++ P + +L + ++D L ++G IL E A+ + Y A Y++M Sbjct: 289 GRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLG 348 Query: 375 ALWRENPTALIGANQRLMTMAALLHVDPQGGALLPELIRASGLDAAAWLERYVDAYLTPL 434 +WRENP + ++ + MA L+ D L I SGLDA WL + + PL Sbjct: 349 VIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPL 408 Query: 435 VHCFYAHDLVFMPHGENVILVVENHVPVRAFMKDIAEESSILNPN----AALPENARRLA 490 H + + + HG+N+ L ++ VP R +KD + ++ +LP+ R + Sbjct: 409 YHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVT 468 Query: 491 ADVPEEYKLLTIFVDVFEGYFRHLSQVLVDNGVMDEDAFWKLVAGRIIAYQEAHPERLEK 550 + + +Y + + F R +S ++V GV E F++L+A + Y + HP+ E+ Sbjct: 469 SRLSADYLIHDLQTGHFVTVLRFISPLMVRLGV-PERRFYQLLAAVLSDYMKKHPQMSER 527 Query: 551 YRQYDLFAPEMIHSCLNRLQLA 572 + + LF P++I LN ++L Sbjct: 528 FALFSLFRPQIIRVVLNPVKLT 549
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 75.6 bits (186), Expect = 5e-17 Identities = 94/377 (24%), Positives = 137/377 (36%), Gaps = 35/377 (9%) Query: 36 LPAFGALGREFAVPQETVQLTLGVYMACYASMLLLH----GTLSDSLGRRRVVLAALGVY 91 +P L R+ V V G+ +A YA M G LSD GRR V+L +L Sbjct: 25 MPVLPGLLRDL-VHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGA 83 Query: 92 VCGALMAALAPGFGWLLAGRAVQGLSAGAGIVVGQAIIRDCYDGAVARRAMSYLILVFNL 151 + A AP L GR V G++ G V G A I D DG R ++ F Sbjct: 84 AVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG-AYIADITDGDERARHFGFMSACFGF 142 Query: 152 SPALAPILGGYLAAHQGWRSIFLLLTALAAAAWLLCARRLPETLPPDRRQPLAWRTLGGN 211 P+LGG + + F AL +L LPE+ +RR PL L Sbjct: 143 GMVAGPVLGGLMGGF-SPHAPFFAAAALNGLNFLTGCFLLPESHKGERR-PLRREAL-NP 199 Query: 212 YARVLGNRRYAALGLAFSLLFAAQGFLIGAAPD-----FITNVLGLPETDFAYLFVPL-V 265 A R + ++ F Q L+G P F + T + Sbjct: 200 LASFRWARGMTVVAALMAVFFIMQ--LVGQVPAALWVIFGEDRFHWDATTIGISLAAFGI 257 Query: 266 VGAMAGALLAARKAGRWSDGRITLLAYLLMGGSCLAYVLYMAAAEPPRLPWAVLLPGLFT 325 + ++A A++ A R + R +L M Y+L A W + Sbjct: 258 LHSLAQAMITGPVAARLGERRALMLG---MIADGTGYILLAFATR----GWMAFPIMVLL 310 Query: 326 CGLAMGVPAMTLRILGHVPDLSGTAASVLGFMQMLTFSVASGWGVPLVYGQPLRLAVAIL 385 +G+PA+ + V + G + LT S+ S G PL++ AI Sbjct: 311 ASGGIGMPALQAMLSRQVDEERQGQLQ--GSLAALT-SLTSIVG-PLLFT-------AIY 359 Query: 386 ACVAASAAGWAWLHRCA 402 A + GWAW+ A Sbjct: 360 AASITTWNGWAWIAGAA 376
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 41.9 bits (98), Expect = 2e-06 Identities = 57/263 (21%), Positives = 101/263 (38%), Gaps = 39/263 (14%) Query: 85 PKRVVALGLGADDLVLSLGVVPVGVGRADWGGDSDHYWPWVRAAIEARGQPLPER---IT 141 P R+VAL +L+L+LG+VP GV D+ +Y WV PLP+ + Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGV------ADTINYRLWVSEP------PLPDSVIDVG 82 Query: 142 VYPELDIEKIIALRPDVVL-APFSGVSPEAYAQLSRLVPVVGYPEQPFLTPVD---TQID 197 + E ++E + ++P ++ + G SPE L+R+ P G+ P+ + Sbjct: 83 LRTEPNLELLTEMKPSFMVWSAGYGPSPE---MLARIAPGRGFNFSDGKQPLAMARKSLT 139 Query: 198 LIAAALGTREAAAPLKARIHDALAQAARRYPELSGKTFAYVRADLGSGNFAAYVAGDPRV 257 +A L + AA A+ D + R+ + + V G + Sbjct: 140 EMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTL---IDPRHMLVFGPNSL 196 Query: 258 --DTLSAMGLTLAPSVRGLRASAGHFAHY----LGFEHADALGDADILVSWFYTPQERDR 311 + L G+ A G + + + A D D+L ++ D Sbjct: 197 FQEILDEYGIP--------NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDA 248 Query: 312 TAAMPLYASIPAVRRGAYVALSD 334 A PL+ ++P VR G + + Sbjct: 249 LMATPLWQAMPFVRAGRFQRVPA 271
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.018 Identities = 14/64 (21%), Positives = 20/64 (31%), Gaps = 16/64 (25%) Query: 48 VGPNGCGKSTLLRVLGGALAPS----------------QGEAFLDGANLASLRRKAVARR 91 G G GKSTL+ L G S G + + + + RR Sbjct: 602 EGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELSEMTAFRRADAEAV 661 Query: 92 LAYL 95 A+ Sbjct: 662 KAFF 665
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.5 bits (66), Expect = 0.032 Identities = 35/146 (23%), Positives = 58/146 (39%), Gaps = 14/146 (9%) Query: 292 SMFIELGTLVWFGHLSDRIGRRTVYLIGSAGLMLAAFPFFWLVQTREPVWIFLAFFLGNT 351 + +GT V +G LSD++G + + L G + F + + + I F G Sbjct: 59 MLTFSIGTAV-YGKLSDQLGIKRLLLFGIIINCFGSVIGF-VGHSFFSLLIMARFIQG-- 114 Query: 352 VCHAAMIGTQPAYFAELFPPEVRYTGLALGHELASVFAG-GLSPLIAMALLRKYESATPV 410 AA A P E R G A G + V G G+ P I + + Sbjct: 115 AGAAAFPALVMVVVARYIPKENR--GKAFGLIGSIVAMGEGVGPAIGGMIAHY------I 166 Query: 411 AW-FLVGMAAITVITLLLTREPARQE 435 W +L+ + IT+IT+ + ++E Sbjct: 167 HWSYLLLIPMITIITVPFLMKLLKKE 192
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 30.2 bits (68), Expect = 0.014 Identities = 10/45 (22%), Positives = 14/45 (31%), Gaps = 4/45 (8%) Query: 144 GLPAPATPVPPLPDAPIPAAELGPGDTLAILYT--SGTSGLSKGV 186 L PV P ++ L I + G + L K V Sbjct: 28 NLGLTLLPVEPSTQVNAASS--HTKPPLVIFLSGDGGWATLDKAV 70
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 30.6 bits (69), Expect = 0.022 Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 8/77 (10%) Query: 283 LGGLAIGIGGLIDPAALGVGYDNI-RHLLAGDLALQAVLLLLVVKV--AIWSIALGSGTS 339 + G+ + IG L+D A + V +N+ R ++ L + + ++ A+ IA+ Sbjct: 395 MFGMVLAIGLLVDDAIVVV--ENVERVMMEDKLPPKEATEKSMSQIQGALVGIAM---VL 449 Query: 340 GGVLAPLLIFGGALGAL 356 V P+ FGG+ GA+ Sbjct: 450 SAVFIPMAFFGGSTGAI 466
>PF06580#Sensor histidine kinase Length = 349 Score = 29.8 bits (67), Expect = 0.025 Identities = 34/224 (15%), Positives = 69/224 (30%), Gaps = 36/224 (16%) Query: 201 TPATWPWLPWLLWALTSALLVAGVA----ASRRSRAEARRQQEQARVAAMARLSTLGEMA 256 P + L ++ + + + + +Q ++A+MA+ + L + Sbjct: 108 KPVAFTLPLALSIIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALK 167 Query: 257 AGI-AHELNQPLTAILAQTRAAQRLLDDDEERPTVRRALLASAEQAKRAADIITRMRALV 315 A I H + L I A E +A +++T + L+ Sbjct: 168 AQINPHFMFNALNNIRALIL-----------------------EDPTKAREMLTSLSELM 204 Query: 316 QPSAPGRREALDPDALVASLRFLR---EPELARQGIQLSWRNASPQARPLADRVALEQIL 372 + S L L + + + +L + N A + D ++ Sbjct: 205 RYSLRYSNARQVS--LADELTVVDSYLQLASIQFEDRLQFENQINPA--IMDVQVPPMLV 260 Query: 373 HNLVQNA-ADALAGASGARHIALEGRAEGATYVFSVSDNGPGIA 415 LV+N +A I L+G + T V + G Sbjct: 261 QTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLAL 304
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.5 bits (235), Expect = 7e-25 Identities = 33/160 (20%), Positives = 61/160 (38%), Gaps = 7/160 (4%) Query: 6 QSPLVYLVDDDDAVRDALALLLRTVGLRSESHADPQQFLAQLAPQAIGCVVLDIRMPGIS 65 + + DDD A+R L L G ++ +A VV D+ MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 66 GLDVLARLADT-SDLPVVMLTGHANVDLCRRAFKGGAMEFLQKPVDDDVFLDAVQAAVRG 124 D+L R+ DLPV++++ +A + GA ++L KP D + + A+ Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA- 120 Query: 125 HIARRERLAVTQAAADRLARL---STREHAVLERIVQGMS 161 + R + + + L S + + + M Sbjct: 121 --EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQ 158
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 41.1 bits (96), Expect = 3e-07 Identities = 19/102 (18%), Positives = 36/102 (35%), Gaps = 7/102 (6%) Query: 29 PWLEPASLREADLDAQTEGERIWVASAADDVLAGFVSL---WEPDDFVHHLYVGRAWRRQ 85 P+ + + D+ E + ++ G + + W + + V + +R++ Sbjct: 45 PYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKK 104 Query: 86 GVARALLRALPGW----PATRYRLKCLRRNAAALAFYRACGF 123 GV ALL W L+ N +A FY F Sbjct: 105 GVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 39.8 bits (93), Expect = 1e-05 Identities = 16/140 (11%), Positives = 42/140 (30%), Gaps = 1/140 (0%) Query: 35 VAVSVAAARSGPLPRDLHALGTITPLARV-VLRSQVDGQLQRLHYTEGQAVRRGQLLAEI 93 + ++ + G + A G +T R ++ + ++ + EG++VR+G +L ++ Sbjct: 68 LVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKL 127 Query: 94 DPRPYQAALAAAEGELAHVEALLGNAEIDLRRYRQLARQEAVAGQQLDTAEAQARSYAAQ 153 +A + L +I R E + Sbjct: 128 TALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRL 187 Query: 154 RQRLAAAVADARRLLALTRI 173 + + + + Sbjct: 188 TSLIKEQFSTWQNQKYQKEL 207 Score = 29.4 bits (66), Expect = 0.024 Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 11/64 (17%) Query: 60 LARVVLRSQVDGQLQRLH-YTEGQAVRRGQLLAEIDPRPYQAALAAAEGELAHVEALLGN 118 V+R+ V ++Q+L +TEG V + L I P E + V AL+ N Sbjct: 325 QQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVP----------EDDTLEVTALVQN 374 Query: 119 AEID 122 +I Sbjct: 375 KDIG 378
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 791 bits (2045), Expect = 0.0 Identities = 291/1038 (28%), Positives = 482/1038 (46%), Gaps = 33/1038 (3%) Query: 3 LSRPFILRPVATSFLMLALLLSGILAWRMLPVAALPQVDYPIIQVTTPYPGASPDVTARA 62 ++ FI RP+ L + L+++G LA LPVA P + P + V+ YPGA Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 VTAPLERRFGQIPGLKQMSSSSGS-GISVITLQFSLDVSLGVAEQEVQAAISASGSLLPS 121 VT +E+ I L MSS+S S G ITL F +A+ +VQ + + LLP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 DLPTPPVYRKVNPADVPILTLAVTSDSLPLPQ--VYDLVDTRMTQRLAQLSGVGMVSLAG 179 ++ + + ++ SD+ Q + D V + + L++L+GVG V L G Sbjct: 121 EVQQQGISV-EKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 180 GQRPAVRVQANPMALAARGLQLSDLQEAIAKANSNQPKGSFDGPV------RSVIMDAND 233 Q A+R+ + L L D+ + N G G + + A Sbjct: 180 AQY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 234 QLQSAQEYRDLIV-AWRNGAPVRLGEVATVEDGAEDRYLAAWVDRQPAVLVNIQRQPGAN 292 + ++ +E+ + + +G+ VRL +VA VE G E+ + A ++ +PA + I+ GAN Sbjct: 239 RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGAN 298 Query: 293 VIAVADQVKALLPQLTASLPAAVQVRVLTDRTESIRASVRGVQWELAFAVGLVVLVTFLF 352 + A +KA L +L P ++V D T ++ S+ V L A+ LV LV +LF Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 353 LRNLPATLIPSLAVPLSLIGTFGVMHLAGFSTNNLTLMALTIGAGFVVDDAIVMLENIAR 412 L+N+ ATLIP++AVP+ L+GTF ++ G+S N LT+ + + G +VDDAIV++EN+ R Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 413 Y-REQGHSPMAAALKGAGQIGFTLVSLTLSLIAVLIPLLFMEDVVGRLFREFAITLAVAI 471 E P A K QI LV + + L AV IP+ F G ++R+F+IT+ A+ Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 472 LISLAVSLTLTPMMCARLLPP----HAERPPGL-------LDRLQARYAGWLDVTLRHQR 520 +S+ V+L LTP +CA LL P H E G D Y + L Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTG 538 Query: 521 LTLLAMLATVALTALLYLAVPKGFFPAQDGGVLQGVTQSAQSTSFEAMSQRQQALAQSLL 580 LL VA +L+L +P F P +D GV + Q + E + + L Sbjct: 539 RYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYL 598 Query: 581 QD--PDVASLSSFIGIDGMNATLNTGRLLVNLKPWSERGAPLADIMARLDARARQVRGI- 637 ++ +V S+ + G N G V+LKPW ER A + ++ I Sbjct: 599 KNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658 Query: 638 SLYLQPVQELNIEDRVSRGQYQFTLTS---PDAALLARWSRALAQRLDAAP-QLADISSD 693 ++ P I + + + F L L + L P L + + Sbjct: 659 DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 694 LQGGGRQAYLEVSRDAAARLGLTMDDVAQALYNAFGQRQVATLFTQSNQYRVVLEVDPRL 753 Q LEV ++ A LG+++ D+ Q + A G V + ++ ++ D + Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 754 AASPEALERIHLKTADGQPIPLAALATVSERAVPLAVNHLSQFPAVNFSFNLPPGGSLGA 813 PE ++++++++A+G+ +P +A T + + P++ PG S G Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 814 AIAAIEAARQDIAMPPSVELRLQGAAAAFEASLSNTLWLMLAAVVTMYLVLGMLYESAIH 873 A+A +E +P + G + S + L+ + V ++L L LYES Sbjct: 839 AMALME--NLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSI 896 Query: 874 PVTILSTLPSATVGALLALLLTGRPLDLIAVIGIILLIGLVKKNGIMMVDFALESERSRG 933 PV+++ +P VG LLA L + D+ ++G++ IGL KN I++V+FA + G Sbjct: 897 PVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG 956 Query: 934 LAPREAIREAALLRLRPILMTTLAALFGALPLMLATGSGAELRQPLGWVMVGGLLVSQVL 993 EA A +RLRPILMT+LA + G LPL ++ G+G+ + +G ++GG++ + +L Sbjct: 957 KGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 1016 Query: 994 TLFTTPAVYLFFHRLGAG 1011 +F P ++ R G Sbjct: 1017 AIFFVPVFFVVIRRCFKG 1034
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 733 bits (1893), Expect = 0.0 Identities = 291/1035 (28%), Positives = 492/1035 (47%), Gaps = 29/1035 (2%) Query: 1 MIRALLHRPIACIFLALALTLLGAVAWRLLPVAPLPQVDFPTIEVRAELPGASPESMAST 60 M + RPI LA+ L + GA+A LPVA P + P + V A PGA +++ T Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VAAPLERALGGIAGVSAMSSSS-NQGATRVLLQFALDRDINAAARDVQAAINAARAELPS 119 V +E+ + GI + MSS+S + G+ + L F D + A VQ + A LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 120 GMPGNPTYRKVNPSQAPIMALALSS--PTRPAGRLYDLGATVLAQKLSQIVGVGEVTLGG 177 + S + +M S P + D A+ + LS++ GVG+V L G Sbjct: 121 EVQ-QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 178 SSLPAVRVQVNPNALAHYGVALDDLRQSIADAAPMGPQGQLDSA----GQRWEVGTPGQP 233 + A+R+ ++ + L Y + D+ + GQL GQ+ Q Sbjct: 180 AQY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 234 RM--ADDYNGLIVR-HQDGATIRLAQIARVSDSVENRYSSGFHNHDPAVVLTISRQPGAN 290 R +++ + +R + DG+ +RL +ARV EN N PA L I GAN Sbjct: 239 RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGAN 298 Query: 291 IIETIAAINQALPGLRALMPADVDLTVVLDRSPGIHATLREAHVTLGLAVGLVILVVWLF 350 ++T AI L L+ P + + D +P + ++ E TL A+ LV LV++LF Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 351 LGSARAAAIPSVAIPVCLVATFAVMYLWGFSLNNLSLMALIVAAGLVVDDAIVVLENISR 410 L + RA IP++A+PV L+ TFA++ +G+S+N L++ +++A GL+VDDAIVV+EN+ R Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 411 HL-ERGLGPRQAALRGVREVGFTLVAMTLALSVVFVSILFMGGLVERLFREFSITLVAAI 469 + E L P++A + + ++ LV + + LS VF+ + F GG ++R+FSIT+V+A+ Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 470 LISLVVSVAIIPSLCARWLRP-PAEAQTRPSRLRAVFARVHQW----YGASLARVLGHAR 524 +S++V++ + P+LCA L+P AE F Y S+ ++LG Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTG 538 Query: 525 LTLLLLAAVVALNAYLYAQAPKGFLPQQDTGQLMGFVRGDDGFSFQVMQPKIDVYRQLVL 584 LL+ A +VA L+ + P FLP++D G + ++ G + + Q +D L Sbjct: 539 RYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYL 598 Query: 585 KHPAVQD-----VIGYNGGSLGISNSLFLIRLKPASER---RESSAQVIDWLRANAPPVP 636 K+ V G++ + + + LKP ER S+ VI + + Sbjct: 599 KNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658 Query: 637 GGMFFLNVDQDLRMPGGFGNSGDHELAIMASDVPALRQWSRRI-SRAMQDIPELRDVDAV 695 G + G + AL Q ++ A Q L V Sbjct: 659 DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 696 GDAATQQVVINIDRAAARRLGVDMRTIASVLGNSFSQRQVATLYDPMNQYRVVLELDPRY 755 G T Q + +D+ A+ LGV + I + + V D ++ ++ D ++ Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 756 TEDPEVLERVQVVAADGNRVPLSAFSTYEHGLVNDRVFHDGLFAAVGVGFSLAEGVSLQQ 815 PE ++++ V +A+G VP SAF+T + R+ ++ + A G S Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 816 GLAAIDAAMARLMVPAHIQTRLGGDARSFQQSLQDQPWLILGVLVAIYLVLGILYESPLH 875 +A ++ ++L PA I G + + S P L+ V ++L L LYES Sbjct: 839 AMALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSI 896 Query: 876 PLTILSTLPSAGVGALLALRLADIEFSLIALLGLFLLVGVVMKNAILMIDFALGLERREG 935 P++++ +P VG LLA L + + + ++GL +G+ KNAIL+++FA L +EG Sbjct: 897 PVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG 956 Query: 936 LTPEQAIHRAAMLRLRPIVMTNLAGLLGALPLVLGMGEGSELRRPLGVTIVGGLMISQFL 995 +A A +RLRPI+MT+LA +LG LPL + G GS + +G+ ++GG++ + L Sbjct: 957 KGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 1016 Query: 996 TLYTTPIVYLALERL 1010 ++ P+ ++ + R Sbjct: 1017 AIFFVPVFFVVIRRC 1031
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 52.5 bits (126), Expect = 8e-10 Identities = 24/125 (19%), Positives = 48/125 (38%), Gaps = 13/125 (10%) Query: 44 DGRVKAYVVQVAPDVSGLVTAVPVHDNQDVKAGDVLFEIDRARFQLAYDQAQASVRSQQV 103 GR K + P + +V + V + + V+ GDVL ++ + + Q+S+ ++ Sbjct: 93 SGRSKE----IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARL 148 Query: 104 --AREQALRDAKRNRSLGQLV-------AAEALEQSQTKLQQTEAALAQAEVQLNTARLN 154 R Q L + L +L + E+ + + + Q LN Sbjct: 149 EQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELN 208 Query: 155 LERSR 159 L++ R Sbjct: 209 LDKKR 213
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 33.3 bits (76), Expect = 0.002 Identities = 14/104 (13%), Positives = 26/104 (25%), Gaps = 5/104 (4%) Query: 358 TGAVQARIAEAEANTKAAVARFDASVLNALRETESALVVYARQLDR-QAALQAARDQAAQ 416 E T +F N + E L + A + + + Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQ-NQKYQKELNLDKKRAERLTVLARINRYENLSRV 232 Query: 417 AASQ---ARQLFQYGKTDYLTVLDAERTLASNESALAAGQAELS 457 S+ L VL+ E + L +++L Sbjct: 233 EKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLE 276 Score = 30.6 bits (69), Expect = 0.015 Identities = 22/166 (13%), Positives = 47/166 (28%), Gaps = 26/166 (15%) Query: 153 RRAVEAAGADAQAAQAAYDATRVTVAAETARAYANLCSAGMQLASAEHSVKVQQESLDAV 212 +++ A+ Q Y ++ Q S E +++ + Sbjct: 136 TLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQF 195 Query: 213 SRLQRAGRGTALDVTRARSQLAQLRASLPPFQAQQRTALYRLAALTGQTPAEIPTTLLQC 272 S Q Q Q +L +A++ T L R+ + E Sbjct: 196 STWQN--------------QKYQKELNLDKKRAERLTVLARINRYENLSRVE-------- 233 Query: 273 AAAPQLSETIPVGDGAALLRRRPDIRQAERALAAATARIGVATADL 318 +L + + A+ + + + E A + V + L Sbjct: 234 --KSRLDDFSSLLHKQAIAKHA--VLEQENKYVEAVNELRVYKSQL 275
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 119 bits (300), Expect = 9e-35 Identities = 82/261 (31%), Positives = 120/261 (45%), Gaps = 13/261 (4%) Query: 5 MQGKTALVFGAGSSGPGWSNGRAAAALYAREGAHVFAVDLRVESAEETRRIILDEGGRCT 64 ++GK A + GA G A A A +GAH+ AVD E E+ + E Sbjct: 6 IEGKIAFITGAAQG-----IGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 65 ALAADVTDSAQILAAVRAMQAEAGRIDVLHNNVGITEMGDPIEASEESWHRVMDTNLTGV 124 A ADV DSA I ++ E G ID+L N G+ G S+E W N TGV Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 125 FLTCKHVLPVMLAQGGGSIVNISSLASIQVNTYPYTSYYAAKAGLNHLTRALAVRYAPDN 184 F + V M+ + GSIV + S + V +Y ++KA T+ L + A N Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPA-GVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 185 IRVNAVLPGVMDTPLIYTQIAGQFEDVEEMRRRRNAAS-----PMGRMGDAWDVAHAALF 239 IR N V PG +T + ++ A + + E + + + P+ ++ D+A A LF Sbjct: 180 IRCNIVSPGSTETDMQWSLWADE--NGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLF 237 Query: 240 LASDEAKYITGVCLPVDGGKS 260 L S +A +IT L VDGG + Sbjct: 238 LVSGQAGHITMHNLCVDGGAT 258
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 116 bits (292), Expect = 2e-30 Identities = 83/409 (20%), Positives = 170/409 (41%), Gaps = 20/409 (4%) Query: 14 LMVLCLGVLMIVLDTTIVNVALPSIREDLHFTETSLVWVVNAYMLTFGGFLLLGGRLGDL 73 L+ LC+ VL+ ++NV+LP I D + S WV A+MLTF + G+L D Sbjct: 16 LIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 74 LGHRRMFLAGLVLFTVASLACGLARGQ-GLLIAARAAQGLGGAVVSAVSLSLIMNLFTEA 132 LG +R+ L G+++ S+ + LLI AR QG G A A+ + ++ + Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 133 GERARAMGVYGFVCAGGGSLGVLLGGLLTSKLSWHWIFLVNIPIGVAVYALCLRLLPAAR 192 R +A G+ G + A G +G +GG++ + HW +L+ IP+ + L L + Sbjct: 136 -NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI--HWSYLLLIPMITIITVPFLMKLL-KK 191 Query: 193 GAAGGGKLDVAGALTVTASLMLAVYAVVNGNEAGWTSAQSLGLLGAAALLMALFLAIEAR 252 G D+ G + ++ ++ + T++ S+ L + L +F+ + Sbjct: 192 EVRIKGHFDIKGIILMSVGIVFFMLF---------TTSYSISFLIVSVLSFLIFVKHIRK 242 Query: 253 VAEPLMPLALFRLRNVATANVVGVLWAAGMFAWFFVSALYMQLVLGYDAMQVGLAFLPAN 312 V +P + L + + G + + + + M+ V ++G + Sbjct: 243 VTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 313 LIMAAFSLGLSAKLVMRFGIRGPLATGLLMAALGLALFARAPVDGHFAADVLPGMLLLGL 372 + + LV R G L G+ ++ + ++++ + Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLL----ETTSWFMTIIIVFV 358 Query: 373 GAGIAFNPMLLA--AMSDVEPGQSGLASGVVNTAFMMGGALGLAVLASL 419 G++F +++ S ++ ++G ++N + G+A++ L Sbjct: 359 LGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>cloacin#Cloacin signature. Length = 551 Score = 27.4 bits (60), Expect = 0.038 Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 1/66 (1%) Query: 26 GYRGGHHGGYHHHHGGGGGGSGWWIGGAFALAATGLILAANSGPSYAQTGVYAPGVSYTS 85 G GG H +GGG G SG G L+A +A P+ + G VS ++ Sbjct: 51 GSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGF-PALSTPGAGGLAVSISA 109 Query: 86 PPVYAA 91 + AA Sbjct: 110 GALSAA 115
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 74.2 bits (182), Expect = 4e-17 Identities = 37/134 (27%), Positives = 64/134 (47%), Gaps = 11/134 (8%) Query: 179 QSVSFRISNELLFPSGQATLSPSGLDVIKRLAAIL---NKNDYQVSVEGHSDPVPIQTRQ 235 Q+ F + +++LF +ATL P G + +L + L + D V V G++D I + Sbjct: 211 QTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDR--IGSDA 268 Query: 236 FASNWELSSSRATSVLRELVRDGVAGSRLRAVGYAETRPIESNDTPAGRAANRRVELIMD 295 + N LS RA SV+ L+ G+ ++ A G E+ P+ N + ++ + Sbjct: 269 Y--NQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCL-- 324 Query: 296 ITAPAKPVQAEAKG 309 AP + V+ E KG Sbjct: 325 --APDRRVEIEVKG 336
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 37.9 bits (88), Expect = 6e-05 Identities = 53/386 (13%), Positives = 116/386 (30%), Gaps = 69/386 (17%) Query: 40 IAAPLLRRDLGLDLASIGTLTAVFSILGMVGGIAAGGIIARFGARRMLLWGLATVAAGTA 99 ++ P + D AS + F + +G G + + G +R+LL+G+ G+ Sbjct: 35 VSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSV 94 Query: 100 AGALA-PGYGVLLASRVVEGLGFLLITVAGPAALQRLVLPSSRDLAFALWSCYMPAGMAI 158 G + + +L+ +R ++G G + R + +R AF L + G + Sbjct: 95 IGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGV 154 Query: 159 AMLASQAFGDWHAYWWCAGATAVIALGCIAALAPPVPGGAALSWNGLRRDTTDTLGAAGP 218 + + + + + + G Sbjct: 155 GPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVR----------IKGHFDIKGI 204 Query: 219 MLLAASFTLY--------------SLMFFALFT--------------------------- 237 +L++ + S++ F +F Sbjct: 205 ILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLC 264 Query: 238 -------------FLPVLLMDKLGLPLATAG-LYSAVASAANIIGNLGAGVLLSR-GWRR 282 +P ++ D L A G + + + II G+L+ R G Sbjct: 265 GGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLY 324 Query: 283 STLIACASVAMGVVALLIFQSVFAAMPTFLLCVLFSAVGGLIPATLLGTAPLVAPRPALT 342 I +++ + + + ++F G T++ T + + Sbjct: 325 VLNIGVTFLSVSFLTASFL--LETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEA 382 Query: 343 AATVGLVMMGSNLGQVIGPVTVGGVI 368 A + L+ S L + G VGG++ Sbjct: 383 GAGMSLLNFTSFLSEGTGIAIVGGLL 408
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 1e-05 Identities = 12/50 (24%), Positives = 20/50 (40%) Query: 80 VSDAARGSGVGRALEEAAEALARARGCDRIEVHCHERRVDAHRFYHRQGY 129 V+ R GVG AL A A+ + + + + A FY + + Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.9 bits (88), Expect = 2e-04 Identities = 28/197 (14%), Positives = 60/197 (30%), Gaps = 11/197 (5%) Query: 702 QSHADLQAALAARDKARLAAWHASLGDVAAELGRQWRQAGEQTAARHQELEQLLARTAHD 761 + AD ++ +ARL + + EL + E+ + R Sbjct: 131 GAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSL 190 Query: 762 LTAQTQAQAALLENLSTRLETAAGGVTQAWTEAQVRQELANEKLASDNQQALTTAAAAFE 821 + Q L+ +A + + E L+ + L ++ Sbjct: 191 IKEQFSTWQNQKYQKELNLDKK-----RAERLTVLARINRYENLSRVEKSRLDDFSSLLH 245 Query: 822 QHSASLLQTLGQSQAGLQAELAARDQERLAAWTGELGRMAEALRQEWEQAGARSAALQQE 881 + + + L Q ++A L + +L ++ + E+ + + E Sbjct: 246 KQAIAKHAVLEQENKYVEA------VNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNE 299 Query: 882 ICATLAQTAQDIATQTE 898 I L QT +I T Sbjct: 300 ILDKLRQTTDNIGLLTL 316
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 76.9 bits (189), Expect = 8e-19 Identities = 43/142 (30%), Positives = 62/142 (43%), Gaps = 16/142 (11%) Query: 70 ALAAPLAAGRVTLINGRIGISGSVLFALNSDQLQPEGREVLKSLIEPLSAYLKANDEILM 129 + AP A + + VLF N L+PEG+ L L LS D ++ Sbjct: 198 PVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNL-DPKDGSVV 256 Query: 130 VSGFTDDQQVREGNRRFADNWDLSAQRALTVTRALIDEGVPSSLVFAAAFGAEQPVASNA 189 V G+TD R G+ + N LS +RA +V LI +G+P+ + A G PV N Sbjct: 257 VLGYTD----RIGSDAY--NQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNT 310 Query: 190 DEEGR---------AKNRRVEI 202 + + A +RRVEI Sbjct: 311 CDNVKQRAALIDCLAPDRRVEI 332
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 40.6 bits (95), Expect = 2e-05 Identities = 16/109 (14%), Positives = 37/109 (33%), Gaps = 11/109 (10%) Query: 436 ALIDDARHRLARQETERAALRREAAAGAAQSARLRELDEEMAATRQQLVDAEARLAQESE 495 A I+ + +++ A + E + + +L +++L Q Sbjct: 221 ARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQ--- 277 Query: 496 LVRQIHALREELEAAGQEPESETTGKRRGGKAAEPTPAQAQLAELQQQL 544 + +I + +EE + Q ++E K R + L +L Sbjct: 278 IESEILSAKEEYQLVTQLFKNEILDKLR--------QTTDNIGLLTLEL 318
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 51.4 bits (123), Expect = 3e-09 Identities = 70/350 (20%), Positives = 117/350 (33%), Gaps = 16/350 (4%) Query: 38 GATAAQTGYLQTAQTLPFLLLSLPAGVLADRLPRRTLMTSAECVRAASLLALLALLALGG 97 A G L L + G L+DR RR ++ + A + L Sbjct: 39 NDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWV 98 Query: 98 LNLGWLAALGFLGAVGTVAYNVAAPALVPTLVPAPALGQANRWLELARSAAFSAGPALGG 157 L +G + A G GA G V A A + + + ++ AGP LGG Sbjct: 99 LYIGRIVA-GITGATGAV-----AGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGG 152 Query: 158 ALVGGIGAAAAYGLATLLSLLAA--GLLAGLPPQAPRAAARRHLWHELRDGAAFVTGHPL 215 L+GG A + A L+ L G R + G + Sbjct: 153 -LMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTV 211 Query: 216 LRPVLVTAVFFNLAWFVLQAVYVVYAVERLGLGAAGVGVTLGVYGA-GMLAGALAAPWLA 274 + ++ L V A++V++ +R A +G++L +G LA A+ +A Sbjct: 212 VAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVA 271 Query: 275 GRLSFGALIAVGPLCALAASLILLSTLALPSGLWAAVGFFLFGAGPILWTIATTTLRQAI 334 RL + +G + A LA + W A + A + A + Sbjct: 272 ARLGERRALMLG----MIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQ 327 Query: 335 TPNALLGRVSAVILTATFGARPLGALIGAAL--ASRLGLEACLWVSSAGF 382 G++ + T +G L+ A+ AS W++ A Sbjct: 328 VDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGAAL 377
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 194 bits (494), Expect = 2e-58 Identities = 79/398 (19%), Positives = 159/398 (39%), Gaps = 14/398 (3%) Query: 29 LLIVVDMTVLYTALPRLTHDLGVTASSKLWIVNIYALVVSGLLLGMGTLGDRLGHKRLFM 88 V++ VL +LP + +D +S W+ + L S G L D+LG KRL + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 89 MGLAVFGAASLAAAYSPNPAA-LIAARAVLAVGAAMMMPATLSILRLTFADERERAIAIG 147 G+ + S+ + + LI AR + GAA PA + ++ + + R A G Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAF-PALVMVVVARYIPKENRGKAFG 142 Query: 148 VWASVASGGAALGPVIGGFLLEHFWWGSVFLINLPIVLLALPLARRYIPAGQPDRQRPWD 207 + S+ + G +GP IGG + + W +L+ +P++ + + + + +D Sbjct: 143 LIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVRIKGHFD 200 Query: 208 LVGSLQVMVGLILTAYALKELGRAQPSWLDAALACAGGAAMLVVFARRQRGRAHPLIDFA 267 + G + + VG++ S ++ ++F + R P +D Sbjct: 201 IKGIILMSVGIVFFMLFTTSY-----SISFLIVS----VLSFLIFVKHIRKVTDPFVDPG 251 Query: 268 IFRNRSFSSAVASALFAAAALLGMELVFSQRLQLVLGMSPIQA-ALYILPLPLAAFIAGP 326 + +N F V + G + ++ V +S + ++ I P ++ I G Sbjct: 252 LGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGY 311 Query: 327 LAGWLLPKVGSARLLFVALLTSGLGMGGYLFTYDGALAAQMASLCVLGVGIGATMTAASS 386 + G L+ + G +L + + + F + + + G+ T T S+ Sbjct: 312 IGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVIST 371 Query: 387 TIMQSATPERAGMAASIEEVSYELGGALGVTLMGSILS 424 + S + AG S+ + L G+ ++G +LS Sbjct: 372 IVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 55.3 bits (133), Expect = 2e-10 Identities = 33/116 (28%), Positives = 56/116 (48%), Gaps = 1/116 (0%) Query: 45 SAPSIARTFGIPVPEALQTGTAFFVGMLIGAFAFGRLADRIGRRPVLMMAVVIDACAGVA 104 S P IA F P TAF + IG +G+L+D++G + +L+ ++I+ V Sbjct: 36 SLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVI 95 Query: 105 SAFAPDFA-WLLLLRFVTGIGVGGTLPVDYTMMAEFLPSERRGRWLVLLESFWALG 159 F L++ RF+ G G + ++A ++P E RG+ L+ S A+G Sbjct: 96 GFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMG 151
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 35.3 bits (81), Expect = 0.001 Identities = 14/51 (27%), Positives = 24/51 (47%) Query: 819 RATATATATATATATTTATTTATASAATSASVVAAPAVTTATAAAATINAV 869 + T A+ T +T A+ ++ SAA + S+V AP A I+ + Sbjct: 359 KETGAIDASLTTISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGI 409
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 100 bits (251), Expect = 5e-25 Identities = 76/407 (18%), Positives = 155/407 (38%), Gaps = 17/407 (4%) Query: 19 LLAACLTAVLIPLCFTGPAVVLPAISHALGGTPVQLNWILNGYILAYGSVIMVSGSLTDL 78 L+ C+ + L V LP I++ P NW+ ++L + V G L+D Sbjct: 16 LIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 79 YGPRRVWLGGLAWFCAFTFPIAWAPS-AAWIDFLRLMQGVGGAAAFAAAMSSLAPLFHGA 137 G +R+ L G+ C + S + + R +QG G AA A M +A Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 138 ARARAFSLLGTTFGIGLSFGPLVSGWLVQTAGWRWVFHGTGLVGLLGLALVAASVRATAG 197 R +AF L+G+ +G GP + G + W ++ + + L+ + Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLM--KLLKKEV 193 Query: 198 AASGRFDWRGALSFTGALGLFTYGMLLAPENGWRDAAVAGSLLASALLAIAFIATEMRAS 257 G FD +G + + + F ML L+ S L + F+ + + Sbjct: 194 RIKGHFDIKGIILMSVGIVFF---MLFTTSYSI------SFLIVSVLSFLIFVKHIRKVT 244 Query: 258 HPMLDLSLFRGARFVGVQALAASPAFLFIALIAILPGRFIGIDGHSALRAGQLMMGLATP 317 P +D L + F+ ++++P + S G +++ T Sbjct: 245 DPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTM 304 Query: 318 LLVV-PFLAALLTRRFSPAILSSIGLALAAAGLAWLARDLGGDAGRLWLPMSLIGIGIGL 376 +++ ++ +L R P + +IG+ + + L + ++ + ++ + GL Sbjct: 305 SVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLL--ETTSWFMTIIIVFVLGGL 362 Query: 377 PWG--LMDAMAVSVAPPERVGMATGIFNTVRVSADGVAIAVISALLA 421 + ++ + S + G + N ++G IA++ LL+ Sbjct: 363 SFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 48.4 bits (115), Expect = 1e-09 Identities = 21/102 (20%), Positives = 43/102 (42%), Gaps = 10/102 (9%) Query: 60 NLDARAVFIAEQDGQPIGFVCVQQEHDHPGEVLLDNLHVLPPYQGTGAGKLMVARAEAWA 119 + +A F+ + IG + ++ + G L++++ V Y+ G G ++ +A WA Sbjct: 61 EEEGKAAFLYYLENNCIGRIKIRSNWN--GYALIEDIAVAKDYRKKGVGTALLHKAIEWA 118 Query: 120 RARGAARLYLYALEGNTRAIAFYERQGWQYTGSEIDRIGGIE 161 + L L + N A FY + + IG ++ Sbjct: 119 KENHFCGLMLETQDINISACHFYAKHHF--------IIGAVD 152
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 128 bits (322), Expect = 3e-38 Identities = 88/253 (34%), Positives = 132/253 (52%), Gaps = 15/253 (5%) Query: 5 GKAALVTGGTRGIGAAIVRSLAQRGAAVAFTYANSDSAANELRRELGASGARVLGIKADS 64 GK A +TG +GIG A+ R+LA +GA +A N + ++ L A AD Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLE-KVVSSLKAEARHAEAFPADV 66 Query: 65 RDPAAVRAAVDHTARELGRLDILVNSAGVFPSGPIEDATLQEIDDTLAIHARAVFVASQA 124 RD AA+ RE+G +DILVN AGV G I + +E + T ++++ VF AS++ Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 125 ALAHMGA--GGRIISIGSCFAQRVPYGGVTLYAMSKSALIGFTKGLAREVGERGITVNIV 182 +M G I+++GS VP + YA SK+A + FTK L E+ E I NIV Sbjct: 127 VSKYMMDRRSGSIVTVGSN-PAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 183 DPGSTDTDMNPADGPAASAELALMA-----------VKRYARPAEIAAAVAYLASAESQF 231 PGST+TDM + + ++ +K+ A+P++IA AV +L S ++ Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 232 ITGSSLAIDGGFT 244 IT +L +DGG T Sbjct: 246 ITMHNLCVDGGAT 258
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 52.3 bits (125), Expect = 7e-11 Identities = 29/161 (18%), Positives = 51/161 (31%), Gaps = 8/161 (4%) Query: 1 MRTFWTQGYEGTSIQDLVAAMGVNKPSLYATFGCKEEIFREAVELYDRLEGRATSHSLAN 60 +R F QG TS+ ++ A GV + ++Y F K ++F E+++ E L Sbjct: 21 LRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF---SEIWELSESNIGELELEY 77 Query: 61 APTAREAVETMLRANARAYVVQDG-----PRGCMIVLSSLLGAPENESVRAFLASNRLNG 115 ++LR + I+ E V+ + L Sbjct: 78 QAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLES 137 Query: 116 ETLLRERLAQGIAQGDLTATADIAQLAAFYTTVLEGLSIQA 156 + + L I L A + A + GL Sbjct: 138 YDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENW 178
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 68.3 bits (167), Expect = 5e-14 Identities = 41/160 (25%), Positives = 71/160 (44%), Gaps = 6/160 (3%) Query: 695 RIWLAEDTPEIREFLVEELASLGFLVESEADGRGMVARIQADDARRPDLILTDHRMEGAD 754 I +A+D IR L + L+ G+ V ++ + I A D DL++TD M + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD---GDLVVTDVVMPDEN 61 Query: 755 GSAVLRAARARWPDLPVVAVSATPQETPPLDG--AGYDASLLKPINLVELRHLLGRLLHL 812 +L + PDLPV+ +SA + G L KP +L EL ++GR L Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 813 ATNPAANEPAPAASPLPRLSRAE-LEQVQRLLDIGGISDL 851 + + +P + R+ ++++ R+L +DL Sbjct: 122 PKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDL 161
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.6 bits (178), Expect = 1e-16 Identities = 39/158 (24%), Positives = 65/158 (41%), Gaps = 11/158 (6%) Query: 20 RVLVVEDRPEDRMLLVDFLTSQDCRVYVAEDGNDGYRKAQLVQPDIILMDVNMPVCDGLA 79 +LV +D R +L L+ V + + +R D+++ DV MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 80 A-CRLLKADPATRAIPVIFLTAASLPMERVAGLSAGAVDYVAKPFDFEEVRL---RLLIH 135 R+ KA P +PV+ ++A + M + GA DY+ KPFD E+ R L Sbjct: 65 LLPRIKKARP---DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 136 LRVTPVAQPASAAGPCEDGAPAAGTGSTLDGVLFRAAR 173 + P + +DG P G + + + AR Sbjct: 122 PKRRPSKLEDDS----QDGMPLVGRSAAMQEIYRVLAR 155
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 30.9 bits (69), Expect = 0.017 Identities = 18/66 (27%), Positives = 28/66 (42%), Gaps = 6/66 (9%) Query: 22 GAEPGRQLPQPVMPESTPTAPPVTVQQGGATEAPAGADKLTFTLTDMRV-EGVTRYPADT 80 + PG Q P +TP P GAT P A T+ + + +PAD+ Sbjct: 419 ASPPGNQNPS----STTPVVPKPVPVYEGATLTPVKATPETYPGVITLPEDLIIGFPADS 474 Query: 81 -LRPLY 85 ++P+Y Sbjct: 475 GIKPIY 480
>PF05860#haemagglutination activity domain. Length = 117 Score = 71.0 bits (174), Expect = 4e-16 Identities = 31/109 (28%), Positives = 51/109 (46%), Gaps = 7/109 (6%) Query: 44 PTGGNVVAGGATINDRGNGTLDINQSTGKAIINWKDFSIGANETVNFRQPGSNSITLNRV 103 P N+ G T Q+ ++++FS+ + T F P + ++RV Sbjct: 10 PINSNITTEGNTRIIERG-----TQAGSNLFHSFQEFSVPTSGTAFFNNPTNIQNIISRV 64 Query: 104 VGNDPSAIFGRLNANGT--VMLVNPNGVLFGKGARIDVGGLVATTANIS 150 G S I G + AN T + L+NPNG++FG+ AR+D+GG + Sbjct: 65 TGGSVSNIDGLIRANATANLFLINPNGIIFGQNARLDIGGSFVGSTANR 113
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 33.4 bits (76), Expect = 0.001 Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 9/58 (15%) Query: 2 PFTRRHALGALAALPLLPRLAFAQAQADFPTR-------PVRLL--VGFAPGGLTDIA 50 +RR L A+A PLL ++ A A A P R PV LL +G P G+ D Sbjct: 6 LISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVADTI 63
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.2 bits (216), Expect = 4e-22 Identities = 32/167 (19%), Positives = 69/167 (41%), Gaps = 14/167 (8%) Query: 3 VLLVEDDAMLGDALRSSMVGAGLRVDWVRDVPAARLALVEHGYGAVLLDLGLPGGSGLAV 62 +L+ +DDA + L ++ AG V + + V+ D+ +P + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 63 LKHLRARYDATPVLIITARDRLSERVQGLDAGADDYIVKPFQLDELLARLRAVVRRSSNS 122 L ++ PVL+++A++ ++ + GA DY+ KPF L EL+ + + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE---- 121 Query: 123 VVSVLRCRDVQLDPARRVVTRA-GAEVVLSASEYRTLLALMERAGQT 168 + P++ G +V ++ + + ++ R QT Sbjct: 122 ---------PKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQT 159
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 58.4 bits (141), Expect = 6e-12 Identities = 52/209 (24%), Positives = 81/209 (38%), Gaps = 21/209 (10%) Query: 23 ALGAASALSVA-QTMPVKHARGETAVPSNPAKTVVLDLAVLDTLHALGVDVTGVPSAAKL 81 L A ALS M HA P + V L+ ++ L ALG+ GV Sbjct: 11 RLLTAMALSPLLWQMNTAHAAAID-----PNRIVALEWLPVELLLALGIVPYGVADTINY 65 Query: 82 ------PPQLAQYADKRYLKVGSMFEPNYEVIHAAQPQVIFVAGRSAPKYDELAKLAPTV 135 PP D VG EPN E++ +P + + P + LA++AP Sbjct: 66 RLWVSEPPLPDSVID-----VGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 120 Query: 136 DLTVNAKDLVGSVTRNT-ETLAAIYGKQAVAKEKLDALRASIAALHGQAAKAGSALIVLT 194 + ++ R + +A + Q+ A+ L I ++ + K G+ ++LT Sbjct: 121 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT 180 Query: 195 T---GGKMSAYGPGSRFGVIHDAFGFAPA 220 T M +GP S F I D +G A Sbjct: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNA 209
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.1 bits (208), Expect = 7e-21 Identities = 39/137 (28%), Positives = 60/137 (43%), Gaps = 1/137 (0%) Query: 1 MATRRILLIDDDVDLALMLREYLEPTHIELTLAHNSAQGLPLAMQECFDLVLLDLMLPDG 60 M IL+ DDD + +L + L ++ + N+A DLV+ D+++PD Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLDLLRHLR-RHSRRPVIMFTAHGGETDRVLGLELGADDYLTKPFGPRELKARIGAVLR 119 N DLL ++ PV++ +A + E GA DYL KPF EL IG L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RFEEKPEPAPPELSVGA 136 + +P + G Sbjct: 121 EPKRRPSKLEDDSQDGM 137
>PF06580#Sensor histidine kinase Length = 349 Score = 31.0 bits (70), Expect = 0.009 Identities = 12/44 (27%), Positives = 21/44 (47%) Query: 360 IENVLRNALRFAPAGGAIQARLLVDAGEACLEIEDNGPGVPEKE 403 +EN +++ + P GG I + D G LE+E+ G + Sbjct: 264 VENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNT 307
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 33.9 bits (77), Expect = 0.002 Identities = 24/156 (15%), Positives = 55/156 (35%), Gaps = 14/156 (8%) Query: 128 SETEALRRAIVAQFEQYVKLNKKIPPEILTSLAGIDDAGRLADTIAAHLPLKLEQKQKML 187 ++ E + K + E A + + + + + Sbjct: 228 ADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKT-- 285 Query: 188 EIVGTSERLEGLLTQLETEIDILQVEKRIRGRVKKQMEKSQRDYYLNEQVKAIQKELGEG 247 + LE LE + +L R +++ ++ S+ K ++ E + Sbjct: 286 -LEAEKAALEAEKADLEHQSQVLNAN---RQSLRRDLDASREAK------KQLEAEHQKL 335 Query: 248 EEGADIEELEKKIIAAHM--PKEARKKADAELKKLK 281 EE I E ++ + + +EA+K+ +AE +KL+ Sbjct: 336 EEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLE 371
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.6 bits (64), Expect = 0.048 Identities = 12/46 (26%), Positives = 23/46 (50%), Gaps = 3/46 (6%) Query: 109 VELSKSNIMLIGPTGSGKTLLAQTL---ARMLNVPFVMADATTLTE 151 + + +M+ G +G+GK L+A+ L + N PFV + + Sbjct: 156 LMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPR 201
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 41.7 bits (98), Expect = 4e-06 Identities = 34/182 (18%), Positives = 58/182 (31%), Gaps = 36/182 (19%) Query: 41 TTASVTLDTLDTPCLLLDETRMTRNIERLNRLMA-------GHGVQLRPHLKTPKSIEVA 93 AS+ L L + R R+ + GHG+ + Sbjct: 5 IQASLDLQALK------QNLSIVRQAATHARVWSVVKANAYGHGI-----------ERIW 47 Query: 94 RRVMARPEGPAAVSTLQEAEQFAAAGVTD--LLYAVGVAPAKLERVLALRRGGVDLTVVV 151 + A A+ L+EA G L+ LE LT V Sbjct: 48 SAIGAT--DGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQ-----HRLTTCV 100 Query: 152 DSVEAAQAVAARALEEGAAIPALIEIDCDGHRAGVQPGQAGQLLEIARALHAAGCLRGVM 211 S +A+ L A + ++++ +R G QP + + + RA+ G +M Sbjct: 101 HSNWQLKALQNARL--KAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGE-MTLM 157 Query: 212 TH 213 +H Sbjct: 158 SH 159
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 25.5 bits (55), Expect = 0.029 Identities = 12/25 (48%), Positives = 18/25 (72%) Query: 8 IRGYVVAALAAVAAVVLVYLRGRRA 32 I G +VAA+A VA +V+V + G+ A Sbjct: 409 IVGAIVAAIAMVAVIVVVAVVGKGA 433
>cloacin#Cloacin signature. Length = 551 Score = 32.8 bits (74), Expect = 0.003 Identities = 34/126 (26%), Positives = 44/126 (34%), Gaps = 18/126 (14%) Query: 287 GGAGRMSQGWVATTPGVAMAIVVGAGGGTATAGGASSFAGLNPAAGAAGKNAIAGGYGGA 346 GG GR +T G G G G + G+ + NP G +G GG G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 347 GASGGGIAGADRTSLRGGSGGNGGASFFGAGGTGGEAASGSSGLAGSSPDAGAYGAGGGG 406 G GG GN G G GTGG ++ ++ +A P GAGG Sbjct: 63 GNGGG--------------NGNSG----GGSGTGGNLSAVAAPVAFGFPALSTPGAGGLA 104 Query: 407 AGGGGD 412 Sbjct: 105 VSISAG 110 Score = 31.2 bits (70), Expect = 0.010 Identities = 31/99 (31%), Positives = 38/99 (38%), Gaps = 7/99 (7%) Query: 326 GLNPAAGAAGKNAIAGGYGGAGASGGGIAGADRTSLRGGSGGNGGASFFGAGGTGGEAAS 385 G N A + N I GG G G GG G+ +S GG G S GG G Sbjct: 8 GHNTGAHSTSGN-INGGPTGLGVGGGASDGSGWSSENNPWGG-GSGSGIHWGGGSGHGNG 65 Query: 386 GSSGLAGSSPDAGAYGAGGGGAGGGGDGAFGVGGAAGRG 424 G +G +G G G GG + AFG + G Sbjct: 66 GGNGNSG-----GGSGTGGNLSAVAAPVAFGFPALSTPG 99 Score = 30.5 bits (68), Expect = 0.016 Identities = 23/84 (27%), Positives = 30/84 (35%), Gaps = 2/84 (2%) Query: 344 GGAGASGGGIAGADRTSLRGGSGGNGGASFFGAGGTGGEAASGSSGLAGSSPDAGAYGAG 403 GG G A + ++ GG G G GA G ++ + GS G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGG--GASDGSGWSSENNPWGGGSGSGIHWGGGS 60 Query: 404 GGGAGGGGDGAFGVGGAAGRGGVV 427 G G GGG + G G G V Sbjct: 61 GHGNGGGNGNSGGGSGTGGNLSAV 84 Score = 29.3 bits (65), Expect = 0.031 Identities = 23/73 (31%), Positives = 27/73 (36%), Gaps = 13/73 (17%) Query: 365 SGGNGGASFFGAGGTGGEAASGSSGLAGSS-------------PDAGAYGAGGGGAGGGG 411 SGG+G GA T G G +GL P G G+G GG G Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSG 61 Query: 412 DGAFGVGGAAGRG 424 G G G +G G Sbjct: 62 HGNGGGNGNSGGG 74
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.5 bits (113), Expect = 2e-07 Identities = 26/195 (13%), Positives = 70/195 (35%), Gaps = 14/195 (7%) Query: 431 QLTEALEKNARLEAAIRAVNPEDDRISSKAIREREAETRKKFQDKDAVSAGQNSLSGQLA 490 L +A + R + R++ E +++ + + ++ +++ Sbjct: 142 SLLQARLEQTRYQILSRSI--ELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQ 199 Query: 491 AMQAQARMREEALRAETAALEGQ-----RAAGLLSEEAFIRRRAAAQRA-ALSDELDIAR 544 + Q + + RAE + + + + ++A A L+ Sbjct: 200 NQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQEN 259 Query: 545 KQADIAGGKKQIAERERYTGRVQELEAQIARSQQQEATDIEKYQAKIRGALRATQLDIAN 604 K + E Y +++++E++I ++++ + ++ +I LR T +I Sbjct: 260 KYVEAVN------ELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGL 313 Query: 605 YSETRALQESRQNNA 619 + A E RQ + Sbjct: 314 LTLELAKNEERQQAS 328
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 30.3 bits (68), Expect = 0.019 Identities = 16/70 (22%), Positives = 22/70 (31%), Gaps = 1/70 (1%) Query: 608 LWVAEHLGLTRKTEAWWDAMAAKLDALPPPADSVEADDAPPPAARGRRPSPAVPAEAAPA 667 V + + L + M A D PP A + P P P P EA Sbjct: 35 TSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPE-PEPEPIPEPPKEAPVV 93 Query: 668 KPRAPPRPAR 677 + P+P Sbjct: 94 IEKPKPKPKP 103
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 25.7 bits (56), Expect = 0.009 Identities = 9/22 (40%), Positives = 17/22 (77%) Query: 7 MLVMFVIGFGVGVIYGRMKGMS 28 ++ +F +G G+GV+ GR+ G+S Sbjct: 43 LIYLFGLGAGLGVMVGRVGGVS 64
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 30.9 bits (70), Expect = 5e-04 Identities = 13/33 (39%), Positives = 18/33 (54%), Gaps = 4/33 (12%) Query: 56 EDQQVQRIRRLAEEAGVP----PALAETILREV 84 D QVQ +R++AEE GVP LA + + Sbjct: 288 TDAQVQTVRKIAEEEGVPILQRIPLARALYWDA 320
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 45.5 bits (108), Expect = 2e-07 Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 21/127 (16%) Query: 97 LLTRFIAELKRRAETAAGRDFTRAVLGRPVFFVDDNPAADQTAQDTLGEIARSVGFTDIE 156 +L FI ++ + R R ++ PV A Q + + E A+ G ++ Sbjct: 90 MLQHFIKQVHSNS---FMRPSPRVLVCVPV-------GATQVERRAIRESAQGAGAREVF 139 Query: 157 FQFEPLAAAFDYESQIDREELVLVIDIGGGTSDFSLIRLGPGRAAKPDRRDDILAYGGVH 216 EP+AAA + +V+DIGGGT++ ++I L ++ V Sbjct: 140 LIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN-----------GVVYSSSVR 188 Query: 217 IGGVDFD 223 IGG FD Sbjct: 189 IGGDRFD 195
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 30.2 bits (68), Expect = 0.014 Identities = 17/96 (17%), Positives = 32/96 (33%), Gaps = 3/96 (3%) Query: 273 FFAGALIQRFGLAKVLGAGMLLNVACALIAMASPSLPAFYAALFCLGVGWNFMFVGGTTL 332 + G L+ R G VL G+ L A L + + + + + T Sbjct: 311 YIGGILVDRRGPLYVLNIGVTFLSVSFLTASF---LLETTSWFMTIIIVFVLGGLSFTKT 367 Query: 333 LAQSYRPSERARAQGAAEMLRYAATAVATLAAGPAL 368 + + S + + A M T+ + G A+ Sbjct: 368 VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 40.0 bits (93), Expect = 2e-06 Identities = 31/132 (23%), Positives = 52/132 (39%), Gaps = 15/132 (11%) Query: 3 SALIVIDVQRALFETTPEPAD-ASAVLARINDLAERARAAAAPVIYVQHEAAGSPLAQG- 60 + L++ D+Q + A + + A I L + PV+Y + +P + Sbjct: 31 AVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDDRAL 90 Query: 61 -----EPGWQLD-------TRLRPADGDIRIRKTTPDSFLRTGLGDALSQAGVTQLVVCG 108 PG T L P D D+ + K +F RT L + + + G QL++ G Sbjct: 91 LTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITG 150 Query: 109 -YASEFCVDTTV 119 YA C+ T Sbjct: 151 IYAHIGCLVTAC 162
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 96.5 bits (240), Expect = 1e-23 Identities = 75/389 (19%), Positives = 138/389 (35%), Gaps = 12/389 (3%) Query: 30 MATLDTSMTNTALPSMASQLGVGAADVIGVVTVYQLVMVATMLPLAALAGKIGHRRVFLP 89 + L+ + N +LP +A+ A V T + L L+ ++G +R+ L Sbjct: 25 FSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLF 84 Query: 90 ALWLFLAASVWCGAAQSLWS-LEAARAAQGLAAAALMGCNMALVSAIYRKEELGRGMGLN 148 + + SV S +S L AR QG AAA M +V+ KE G+ GL Sbjct: 85 GIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLI 144 Query: 149 AMIAAASLAGGPVLASAMLTVLSWHWLFYVNVPFCLVALMLAGRHLPRLPGDGKA-LDAG 207 I A GP + + + HW + + +P + + L + K D Sbjct: 145 GSIVAMGEGVGPAIGGMIAHYI--HWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIK 202 Query: 208 AAVLCALAFGLAVQGLERAAQPDWGTALIWACCALSWALLLRRERLSAHAIVPLDLLRLA 267 +L ++ + + ++ LS+ + ++ R V L + Sbjct: 203 GIILMSVGIVFFMLFTTSYS---ISFLIVS---VLSFLIFVKHIRKVTDPFVDPGLGKNI 256 Query: 268 PFSMAVLVCVLAFAAQGAAMVALPFLLNQTLGRGIAEVG-MLIAPWPVMGACLAPFSGKW 326 PF + VL + F + +P+++ AE+G ++I P + G Sbjct: 257 PFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGIL 316 Query: 327 SDRMSASLLGAVGLALLAAGLLILSGLPAGAPIWAVMLPMALCGTGFGLFLSPNQRFIMF 386 DR + +G+ L+ L S L + ++ + + G + + Sbjct: 317 VDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVIST-IVSS 375 Query: 387 SVPAHRASVASGLSGLARLLGQTMGAAFV 415 S+ A L L + G A V Sbjct: 376 SLKQQEAGAGMSLLNFTSFLSEGTGIAIV 404
>LIPOLPP20#LPP20 lipoprotein precursor signature. Length = 175 Score = 28.6 bits (63), Expect = 0.008 Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 9/112 (8%) Query: 14 IRGLSVLATLLEKGAAHAAANGI---DPAELVNARLAPDMYPLSGQVQRASDASKFAVQR 70 I G+SV+A ++ G +HA +GI + A + APD + G +++ + K++ Sbjct: 8 ILGMSVVAAMVIVGCSHAPKSGISKSNKAYKEATKGAPDW--VVGDLEKVAKYEKYSGVF 65 Query: 71 LSQVE---SPRFPDEETTFEQLRQRVADTIAYLRSVPADKLDGAEARTITLS 119 L + E + D T + R A+ A L+S L+ + RT+ S Sbjct: 66 LGRAEDLITNNDVDYSTNQATAKAR-ANLAANLKSTLQKDLENEKTRTVDAS 116
>cdtoxina#Cytolethal distending toxin A signature. Length = 258 Score = 28.1 bits (62), Expect = 0.049 Identities = 14/45 (31%), Positives = 18/45 (40%), Gaps = 6/45 (13%) Query: 33 SPAQSSESSPVPAKAAAAPEKGAAPAAAATAQPAPAKAPAVATLG 77 P+ P+P A P GA P P P APAV+ + Sbjct: 46 VPSPDEPGLPLPGPGPALPTNGAIPI------PEPGTAPAVSLMN 84
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 36.3 bits (84), Expect = 6e-05 Identities = 17/134 (12%), Positives = 38/134 (28%), Gaps = 2/134 (1%) Query: 24 AAAALCAAGLSVALPAQAESMEERLRAQLRSTTQQLQQLQSEQAQVNAAKAAAEAQRDAA 83 + + L + + + Q L + ++E+ V A E Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 84 QKELVALRSQLASAKGQAEKLAGQQEAVMESAQAQVAASHAQLGKFKGAYDEL-LTLSRA 142 + L S L + Q+ +E A ++ +QL + + Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVE-AVNELRVYKSQLEQIESEILSAKEEYQLV 292 Query: 143 KEAERQTLARTLAQ 156 + + + L Q Sbjct: 293 TQLFKNEILDKLRQ 306
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 42.3 bits (99), Expect = 6e-07 Identities = 16/47 (34%), Positives = 18/47 (38%) Query: 57 PLPPPPPPPPEPEKPPEPEPPKEEPVAPPEPEPQPTPEPPKPQDEAP 103 L PP P PE EPEP E PP+ P +P P Sbjct: 54 DLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKP 100 Score = 33.0 bits (75), Expect = 7e-04 Identities = 19/92 (20%), Positives = 31/92 (33%), Gaps = 1/92 (1%) Query: 16 RRWLKLAAVAVALIAAAYALWRWANDMAGVRREAPKATAIIPLPPPPPPPPEPEKPPEPE 75 RR+ ++V + A A + + + AP + + P P P PE Sbjct: 7 RRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQAVQPPPE 66 Query: 76 PPKEEPVAPPEPEPQPTPEP-PKPQDEAPPRP 106 P E P P P + + P+P Sbjct: 67 PVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKP 98
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 30.3 bits (68), Expect = 0.008 Identities = 14/50 (28%), Positives = 24/50 (48%), Gaps = 3/50 (6%) Query: 97 KENQVLGAKLGSLSNAIAGGPYIGLLGTVLGIMVVFLGTAMAGDVNINAI 146 ++ Q G LG + I +G G +L FLGTA++ + I+ + Sbjct: 119 QKYQKAGNILGGGAENIGDN--LGKAGGILSTFQNFLGTALSS-MKIDEL 165
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 36.0 bits (83), Expect = 4e-04 Identities = 36/213 (16%), Positives = 62/213 (29%), Gaps = 27/213 (12%) Query: 242 TDNAKVWSGSYSMPLDKQWSLQFTG--YKSDSNVATIGGTNVLGK--GYSFGMSAIYTLA 297 + + + + L W++ + G G +G S M+ + Sbjct: 390 QEKPRFFQSTLLHGLPAGWTI-YGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTL 448 Query: 298 PQGDWYNSLSVGLDYKKFDETTRFGGNEDLIPLKYVPFTFSYNGYRYSEASQSSIGLSLV 357 P ++ SV Y K + GYRYS + + + Sbjct: 449 PDDSQHDGQSVRFLYNKSLNESGT--------------NIQLVGYRYSTSGYFNFADTTY 494 Query: 358 GASRSFFGLGSDWKEFDDKRYRASPSFALL---RGDGTHTQNLFGDWQ-LGLRAGFQLAS 413 + D ++ + A + T TQ L G L L Q Sbjct: 495 SRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQL-GRTSTLYLSGSHQTYW 553 Query: 414 GALVSNEQFSAGGSTSVRGY---LAAERTGDDG 443 G +EQF AG +T+ L+ T + Sbjct: 554 GTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAW 586
>PF05860#haemagglutination activity domain. Length = 117 Score = 58.3 bits (141), Expect = 8e-12 Identities = 25/99 (25%), Positives = 47/99 (47%), Gaps = 6/99 (6%) Query: 132 TEGGRQLVTI-EQTQSRAILNWDTFNVGRNTTLRFQQKAD-DAVLNRVVGASARPSQIQG 189 TEG +++ Q S ++ F+V + T F + +++RV G S S I G Sbjct: 17 TEGNTRIIERGTQAGSNLFHSFQEFSVPTSGTAFFNNPTNIQNIISRVTGGS--VSNIDG 74 Query: 190 AIQADGT--VLVVNQNGVIFSGTSQVNARNLVVAAATMS 226 I+A+ T + ++N NG+IF ++++ V + Sbjct: 75 LIRANATANLFLINPNGIIFGQNARLDIGGSFVGSTANR 113
>PF05860#haemagglutination activity domain. Length = 117 Score = 60.2 bits (146), Expect = 1e-12 Identities = 25/99 (25%), Positives = 47/99 (47%), Gaps = 6/99 (6%) Query: 132 TEGGRQLVTI-EQTQSRAILNWDTFNVGRNTTLRFQQKAD-DAVLNRVVGASARPSQIQG 189 TEG +++ Q S ++ F+V + T F + +++RV G S S I G Sbjct: 17 TEGNTRIIERGTQAGSNLFHSFQEFSVPTSGTAFFNNPTNIQNIISRVTGGS--VSNIDG 74 Query: 190 AIQADGT--VLVVNQNGVIFSGTSQVNTRNLVVAAATMS 226 I+A+ T + ++N NG+IF ++++ V + Sbjct: 75 LIRANATANLFLINPNGIIFGQNARLDIGGSFVGSTANR 113
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 112 bits (280), Expect = 9e-32 Identities = 85/264 (32%), Positives = 127/264 (48%), Gaps = 9/264 (3%) Query: 2 SKRLEGKVAIVTGAGCVGPGWGNGRAVAVRFAQEGAKVFAVDKSADAMAETLLRAKDAGG 61 +K +EGK+A +TGA G G AVA A +GA + AVD + + + + + K Sbjct: 3 AKGIEGKIAFITGAA-----QGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEAR 57 Query: 62 DITAWTCDATVSADVHAMVQACVERYGRVDILVNNVGGSRRGGPVDLSEADWDAQMDFNL 121 A+ D SA + + G +DILVN G R G LS+ +W+A N Sbjct: 58 HAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNS 117 Query: 122 KSVFLACKHVIPIMQGQGGGAIVNTAS-TSGIRWTGAAQVGYASAKAGIIQLSRVVAVEY 180 VF A + V M + G+IV S +G+ T A YAS+KA + ++ + +E Sbjct: 118 TGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMA--AYASSKAAAVMFTKCLGLEL 175 Query: 181 AKHNIRVNTVVPGQMHTPMVEARLAGQRAGGNVDALLAER-QARIPLGFMGDGTDTANAA 239 A++NIR N V PG T M + A + V E + IPL + +D A+A Sbjct: 176 AEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAV 235 Query: 240 LFLASDEARFVTGTEIIVDGGMSV 263 LFL S +A +T + VDGG ++ Sbjct: 236 LFLVSGQAGHITMHNLCVDGGATL 259
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 475 bits (1223), Expect = e-168 Identities = 189/476 (39%), Positives = 255/476 (53%), Gaps = 37/476 (7%) Query: 2 ARILIVDDDAAFRESLSETLHDLGHTALQASSTVAGLNRLRTEAVDLAIVDLRMPGEDGL 61 A IL+ DDDAA R L++ L G+ S+ + DL + D+ MP E+ Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 VFLRKAAGIAP-VPCIMLTAYASGGNTIEAMRLGAFDHLTKPVARAALVQTLERALDSAR 120 L + P +P ++++A + I+A GA+D+L KP L+ + RAL + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 VAGDDGADADTAPADEFELVSGSEAMREVFKRIGMAARGDATVLIQGETGTGKELVARAL 180 + + D LV S AM+E+++ + + D T++I GE+GTGKELVARAL Sbjct: 124 R---RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180 Query: 181 HRNGARAARPFVAVNCAAIPADLMESELFGHVKGAYTGATGDRAGRFREAEGGTLFLDEI 240 H G R PFVA+N AAIP DL+ESELFGH KGA+TGA GRF +AEGGTLFLDEI Sbjct: 181 HDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 241 GDMPLATQAKILRALQEREITPVGGARTVPVDVRIVAATHRDLPAAVAAGRFREDLWYRL 300 GDMP+ Q ++LR LQ+ E T VGG + DVRIVAAT++DL ++ G FREDL+YRL Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300 Query: 301 QVVPIALPPLRERLGDVLLLAEHFL---RRGGGTPKRLSAAAAQRLLAHNWPGNVRELRN 357 VVP+ LPPLR+R D+ L HF+ + G KR A + + AH WPGNVREL N Sbjct: 301 NVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELEN 360 Query: 358 AMERAAILSRGASIEPEHIGLQ------------------------------PLGIAQDG 387 + R L I E I + A G Sbjct: 361 LVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFG 420 Query: 388 FAIPLDGSLAQAVAALEGAMIRRALAAAAGNRAEAARRLGLSRQQLYRKLAEHGVE 443 A+P G + +A +E +I AL A GN+ +AA LGL+R L +K+ E GV Sbjct: 421 DALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>PERTACTIN#Pertactin signature. Length = 922 Score = 79.0 bits (194), Expect = 5e-17 Identities = 131/552 (23%), Positives = 198/552 (35%), Gaps = 69/552 (12%) Query: 379 GTAFSGTSVFNKLGAGRLTLSGNSAAFTGNTQVQAGTLQVDGVLGGPVDVL--AGARLTG 436 G G ++ ++ + L+ A V + G GP+DV + AR TG Sbjct: 362 GARAQGRALLYRVLPEPVKLTLAGGAQGQGDIVATELPPIPGASSGPLDVALASQARWTG 421 Query: 437 TGRV--GATTNKGTIAPGPRSGFGTLTIAGD---------YAAQGGNLEVRTRLGG---- 481 R + + T S G L +A D A + L V T G Sbjct: 422 ATRAVDSLSIDNATWVMTDNSNVGALRLASDGSVDFQQPAEAGRFKVLMVDTLAGSGLFR 481 Query: 482 -----DDSPTDKLVITGATAGTTPVTVTNIGGAGAQTQRGIQVVQVNGLSAGQFNLANGD 536 D +DKLV+ +G + V N G A + +VQ SA F LAN D Sbjct: 482 MNVFADLGLSDKLVVMRDASGQHRLWVRNSGSEPASGNT-MLLVQTPRGSAATFTLANKD 540 Query: 537 YVIGGRPALVAGAYGYTLQQDSGDGSWYLRSALTDPESPQTGGGSPAPAPGPLYQPGVPV 596 + G Y Y L + G+G W L A P P P P P P P Sbjct: 541 GKVD------IGTYRYRLAAN-GNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQ 593 Query: 597 YEAYANTLMQLSKLPTLRQRVGDRLYEPQGAGRN--------GVWARMEGSTS------R 642 + + P + G L A N +W + S R Sbjct: 594 PPQPPQPPQRQPEAPAPQPPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELR 653 Query: 643 LEPAVS-----TTGQRQDIDD----------WKMQIGVDRVLAGQEDGSRLVGGLALHYG 687 L P QRQ +D+ ++G D +A G +GGLA + Sbjct: 654 LNPDAGGAWGRGFAQRQQLDNRAGRRFDQKVAGFELGADHAVAVAG-GRWHLGGLAGY-- 710 Query: 688 TSDTRVSSVYGNGSIDTTRYGLTPTLTWYGSDGVYVDAQAQATWFDSDLK--SRLAGKLK 745 T R + G G D+ G T+ + G Y+DA +A+ ++D K +K Sbjct: 711 TRGDRGFTGDGGGHTDSVHVG--GYATYIANSGFYLDATLRASRLENDFKVAGSDGYAVK 768 Query: 746 DGRKAQSYGLGLEAGKAFGLREGLALVPQAQLTYVSTRFDRFSDRFGARVESDKGDSLQG 805 + G+ LEAG+ F +G L PQA+L + G RV + G S+ G Sbjct: 769 GKYRTHGVGVSLEAGRRFAHADGWFLEPQAELAVFRVGGGAYRAANGLRVRDEGGSSVLG 828 Query: 806 RLGVALDYRSNGQETGSDRRSNVYGVINLKHEFLDGTRIQVANVPVVSRMSRTWGNLGVG 865 RLG+ + R E R+ Y ++ EF ++ + + + T LG+G Sbjct: 829 RLGLEVGKRI---ELAGGRQVQPYIKASVLQEFDGAGTVRTNGIAHRTELRGTRAELGLG 885 Query: 866 ADYAWSKRYAVY 877 A + +++Y Sbjct: 886 MAAALGRGHSLY 897
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 41.7 bits (98), Expect = 4e-06 Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 14/115 (12%) Query: 346 VLVLDSRSGATLFGRAENDAVPIASLTKLVTAMVVLDTSP----DLSRRIRIDERDALAT 401 ++ +D SG TL ++ P+ S K+V VL L R+I ++D + Sbjct: 42 MIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVD- 100 Query: 402 ASGAASPLP---VGASVTLDTLLKLALMASDNRAAHALARAY--PGGETAFAEAL 451 SP+ + +T+ L A+ SDN AA+ L P G TAF + Sbjct: 101 ----YSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQI 151
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 28.2 bits (63), Expect = 0.022 Identities = 10/28 (35%), Positives = 12/28 (42%) Query: 122 ADNLFEVGQADGWRLYGKTGTGSPGSNG 149 A L GW + KTG G G+ G Sbjct: 213 AGPLIRSVLPAGWFIADKTGAGERGARG 240
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.5 bits (63), Expect = 0.011 Identities = 11/50 (22%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 14 APPSPAAPAPRAPADSEDARGQAPGNAVPEEDIEPADATADDPHPAQAGR 63 PP+PA P+ +E+++ ++ E+D + TA + A+ + Sbjct: 1026 PPPAPATPSETTETVAENSKQESKTVEKNEQD--ATETTAQNREVAKEAK 1073
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 28.5 bits (63), Expect = 0.006 Identities = 15/33 (45%), Positives = 17/33 (51%) Query: 88 PTPGQGTVKGSTANPAPDGRLPGGRAGSGGSKS 120 P +G V + N PDG GG G GGSKS Sbjct: 13 PYDDKGQVIITLLNGTPDGSGSGGGGGKGGSKS 45
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 173 bits (440), Expect = 1e-53 Identities = 78/334 (23%), Positives = 130/334 (38%), Gaps = 36/334 (10%) Query: 10 RALVAGGAGFLGSNLCARLLADGWEVMCVDNFQTGRSRNVAM----LAAHPRFSVVRHDI 65 + LV G AGF+G ++ RLL G +V+ +DN ++ L A P F + D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 66 ------VEPLADVQVDRIYNLACPASPVHYQ-ADPLKTLRTCVLGAMQLLELARRCG-AR 117 + A +R++ + V Y +P + + G + +LE R Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLA-VRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 118 VLQASTSEVYGDPLEHPQREGYWGHVNPVGPRSCYDEGKRCAETIFMEYAAHEGVDVRIA 177 +L AS+S VYG + P + P S Y K+ E + Y+ G+ Sbjct: 121 LLYASSSSVYGLNRKMPFST----DDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGL 176 Query: 178 RIFNTYGPHMSPDDGRVVSNFIVQALAGKPLTIYGDGTQTRSFCYVDDLIDGLVRLMESV 237 R F YGP PD + F L GK + +Y G R F Y+DD+ + ++RL + + Sbjct: 177 RFFTVYGPWGRPD--MALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVI 234 Query: 238 PP-----------------DVRPVNLGNPAELTMLEMADMVRTLTGANVPLVHRDLPVDD 280 P R N+GN + + +++ + G L D Sbjct: 235 PHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGD 294 Query: 281 PTHRCPDISLARERLGWTPLIAPVEGMARTVAYF 314 D E +G+TP +G+ V ++ Sbjct: 295 VLETSADTKALYEVIGFTPETTVKDGVKNFVNWY 328
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 30.1 bits (67), Expect = 0.019 Identities = 29/111 (26%), Positives = 50/111 (45%), Gaps = 5/111 (4%) Query: 199 DNQGHPTDIERYYRAGLRAARQDVLIANAYFFPGYRLLHDLASTARRGVRVRLLLQGEPD 258 D+ +E+ A L A Q+ LIAN + Y + D AS A R + + D Sbjct: 92 DSGAMSHKLEK---ADLLKAIQEQLIANVHSNDDYFEVIDFASDATITDRNGKVYFADKD 148 Query: 259 MLVAQLAASMLYDYLIDAGVEIFEYCKRPLHAKVACVDEDWSTVGSSNLDP 309 V L + ++L+ V + Y ++P+ + VD ++ TV + L+P Sbjct: 149 GSVT-LPTQPVQEFLLSGHVRVRPYKEKPIQNQAKSVDVEY-TVQFTPLNP 197
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.2 bits (68), Expect = 0.018 Identities = 42/245 (17%), Positives = 80/245 (32%), Gaps = 28/245 (11%) Query: 71 AVLFGHLGDRVGRKQSLVITLLLMGVATTLIGLLPSYHSIGLAAVVLLVALRLVQGIAVG 130 A + G L DR GR+ L+++L V ++ P + +L R+V GI Sbjct: 60 APVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAP--------FLWVLYIGRIVAGITGA 111 Query: 131 GEWGGAVLIA---AEHAPPKWRTFLASAPQYGSPIGLILATGVFRLVSDLPKEDFLSWGW 187 IA + F+++ +G G++ + L+ Sbjct: 112 TGAVAGAYIADITDGDERARHFGFMSAC--FG--FGMVAGPVLGGLMGGF--------SP 159 Query: 188 RLPFIISGVLVLVAFVIRRGVNESPELEARLKEKKRESTAPISMVLRERKR--ALLLGIG 245 PF + L + F+ + R ++ S A L+ + Sbjct: 160 HAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVF 219 Query: 246 LCLLGISGFYFVTTLMITYTTTYLKITRSQILDVVTWAGVVE-LISFPIASYIATRVGER 304 + + L + + + I + G++ L I +A R+GER Sbjct: 220 FIMQLVGQVP--AALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGER 277 Query: 305 RFLIW 309 R L+ Sbjct: 278 RALML 282
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 85.0 bits (210), Expect = 7e-21 Identities = 41/107 (38%), Positives = 64/107 (59%), Gaps = 3/107 (2%) Query: 212 VYFDTDKAEVKAESKAALDEM-GKLLNANPK-LKVYVVGHTDNQGTLAGNLELSQKRADA 269 V F+ +KA +K E +AALD++ +L N +PK V V+G+TD G+ A N LS++RA + Sbjct: 221 VLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQS 280 Query: 270 VVKALEAGYKIPAARLSARGVASLAPVAANDAEAGRARNRRVELVAQ 316 VV L + IPA ++SARG+ PV N + + R ++ +A Sbjct: 281 VVDYLISK-GIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAP 326
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 90.3 bits (224), Expect = 7e-22 Identities = 69/422 (16%), Positives = 129/422 (30%), Gaps = 100/422 (23%) Query: 4 TQTPDSRTSTRKSRLMLAGGATLLAGAGWAAWTFLAGAATQTTDNAYVNGHVVAITPQVG 63 +TP SR + ++ + + AT +G I P Sbjct: 49 IETPVSRRPRLVAYFIMGFLVIAF---ILSVLGQVEIVAT-ANGKLTHSGRSKEIKPIEN 104 Query: 64 GAVSAIWADNADRIRAGQTLVEVDP-------ADTQIALAGARADLARARR--------- 107 V I + +R G L+++ TQ +L AR + R + Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNK 164 Query: 108 ---------------------RVQALFASR--------DQAGAEVARRQAELDHAQADVS 138 R+ +L + Q + +++AE A ++ Sbjct: 165 LPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARIN 224 Query: 139 ARR-------------------GIAAQGAITSEEARHAADA--LNAARAALAVAQAAERA 177 A+ A+ +E ++ L ++ L ++ + Sbjct: 225 RYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILS 284 Query: 178 AQAQVDGVTPDTHPDVT--LAQARLRAAALDAQ---------RTTIRAPVGGMVAQRSVQ 226 A+ + VT ++ L Q L + + IRAPV V Q V Sbjct: 285 AKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVH 344 Query: 227 -LGKHVAIGDKLMAVVPLDQ-MWIDANFKEIQLAGICPGQPAVVTVDA-----HGAKVRY 279 G V + LM +VP D + + A + + I GQ A++ V+A +G Sbjct: 345 TEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYG---YL 401 Query: 280 RGRVGDVMAGSGSAFALLPSQNATGNWIKVVQRVPVRINLDPKELADHPLRIGLSAEVTV 339 G+V ++ + G V+ + N + PL G++ + Sbjct: 402 VGKVKNINLDA-------IEDQRLGLVFNVIISIEE--NCLSTGNKNIPLSSGMAVTAEI 452 Query: 340 DT 341 T Sbjct: 453 KT 454
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 119 bits (299), Expect = 3e-31 Identities = 83/380 (21%), Positives = 155/380 (40%), Gaps = 16/380 (4%) Query: 27 SFMAVVDITIANVSVPTISGNLGVSPEIGEWAITFFAIANSICIPLTGWLSRRLGQVRLF 86 SF +V++ + NVS+P I+ + P W T F + SI + G LS +LG RL Sbjct: 23 SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLL 82 Query: 87 VLSVAAFTLASVLCGVAQNFESLLAF-RVLQGMVSGPIVPLSQALLVAIFPPDKRTLALS 145 + + SV+ V +F SLL R +QG + L ++ P + R A Sbjct: 83 LFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFG 142 Query: 146 MWAMTNMAGPVAGPVLGGWLTDDFSWPWIFLVNAPVGIAVVAVTATMFRGRDTPSTRLPV 205 + G GP +GG + W ++ L+ P+ I ++ V M + + Sbjct: 143 LIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLI--PM-ITIITVPFLMKLLKKEVRIKGHF 199 Query: 206 DLRGLILLAVAIGCLQLTLDRGRTLDWFASPFIVTTALLSALGFVFLVIWELGEAHPIVD 265 D++G+IL++V I L F + + ++ ++S L F+ V P VD Sbjct: 200 DIKGIILMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVD 249 Query: 266 LSLFRHRNFAMGTLAVAVGFGLYFAALVLIPLWLQTDMRYTATWAGLATA-PMGVFGILL 324 L ++ F +G L + FG + ++P ++ + + G P + I+ Sbjct: 250 PGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIF 309 Query: 325 APLLGRWVQRGDARVFASLAFVAWSLVAWWRASMTTDVGVGLISLACLLQGIGIGLFLTP 384 + G V R ++ V + V++ AS + +++ + G+ T Sbjct: 310 GYIGGILVDRRGPLYVLNIG-VTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTV 368 Query: 385 LVSLSLAGLPPERIAAASGL 404 + ++ + L + A L Sbjct: 369 ISTIVSSSLKQQEAGAGMSL 388
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 75.0 bits (184), Expect = 6e-17 Identities = 35/167 (20%), Positives = 64/167 (38%), Gaps = 34/167 (20%) Query: 72 GGRQSIGSGVIVDAAQGNILTNHHVVRGATSIRVSLQ------------DGRSFTATVVG 119 I SGV+V + +LTN HVV +L+ +G + Sbjct: 98 PTGTFIASGVVV--GKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITK 155 Query: 120 SDPDTDLAVLRI--------PPDKLQALTLSDSSDLRVGDFVVAIGDPYGLG---QSASS 168 + DLA+++ + ++ T+S++++ +V + G P S Sbjct: 156 YSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESK 215 Query: 169 GIVSALERSSLRAAGYQNFIQTDASINPGNSGGALVNLNGELVGINT 215 G ++ L+ +Q D S GNSG + N E++GI+ Sbjct: 216 GKITYLK---------GEAMQYDLSTTGGNSGSPVFNEKNEVIGIHW 253
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.1 bits (221), Expect = 1e-22 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 1/128 (0%) Query: 6 HILIVDDDREIRELAGNFLKKNGLNVTLAADGRQMRNLLETLTVDLIVLDIMMPGDDGLV 65 IL+ DDD IR + L + G +V + ++ + + DL+V D++MP ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 66 LCRELRAGKHRRTPILLLTARDEDMDRVLGLEMGADDYLVKPFVARELLARIKAILRRTR 125 L ++ P+L+++A++ M + E GA DYL KPF EL+ I L + Sbjct: 65 LLPRIKK-ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 126 MLPPNFQV 133 P + Sbjct: 124 RRPSKLED 131
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 70.6 bits (173), Expect = 7e-16 Identities = 74/349 (21%), Positives = 129/349 (36%), Gaps = 67/349 (19%) Query: 25 AAETSSVTLYGLVDLGTTYER---KDGASSLRQKSGN---QSGSRWGLRGSEDLGNGYKA 78 A + VTLYG + G R +GA + ++G GS+ G +G EDLGNG KA Sbjct: 15 VAAMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLGSKIGFKGQEDLGNGLKA 74 Query: 79 VFRLESGFNANNGTQAQGRMFGRWAYVGLAGGFGEVRLGRQW-----VYGFE-WAGVGSP 132 ++++E + R +++GL GGFG++R+GR W Sbjct: 75 IWQVEQKASIAGT---DSGWGNRQSFIGLKGGFGKLRVGRLNSVLKDTGDINPWDSKSDY 131 Query: 133 FGTGWGQSSNN--ASLGYNDGDFGAG-------------GRVNNAVFYA--TPRLGGWQA 175 G S+ Y+ +F AG GR N+ ++A + GG+ Sbjct: 132 LGVNKIAEPEARLISVRYDSPEF-AGLSGSVQYALNDNAGRHNSESYHAGFNYKNGGFFV 190 Query: 176 GLGYSFESHD-GEAFATDAHDRVLTAGLRYNGGPVAAALTYERLNPNSQLPNKKTAGNLQ 234 G +++ H + ++ Y+ + A++ ++ + N + Sbjct: 191 QYGGAYKRHHQVQENVNIEKYQIHRLVSGYDNDALYASVAVQQQDAKLVEENYSHNSQTE 250 Query: 235 VAGSYDFEWIKLHGTYGNLRNANTGPSAGYDRVNSYLAGVSMPTGKAGTLMASYQRATSS 294 VA + + +GN+ P Y A S+ + Sbjct: 251 VAATLAYR-------FGNVT-----PRVSY----------------AHGFKGSFDATNYN 282 Query: 295 DITGWA-LGYQHDLSKRTNLY--AYVNRLDIRASHTLQT--SVGIRHLF 338 + +G ++D SKRT+ A + S + T VG+RH F Sbjct: 283 NDYDQVVVGAEYDFSKRTSALVSAGWLQEGKGESKFVSTAGGVGLRHKF 331
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 28.0 bits (62), Expect = 0.030 Identities = 19/68 (27%), Positives = 28/68 (41%), Gaps = 14/68 (20%) Query: 15 PDEDPWVRGKPAPEAVVVVPYDPDWPARYARLAQDIAAALGPAALR-IDHVGSTAVPGLP 73 P +VR + +P A V V +P AL + + H+ S+AV GLP Sbjct: 159 PKPSLFVREQKSPSASVTVTLEPG-------------RALDEGQISAVVHLVSSAVAGLP 205 Query: 74 AKPVVDID 81 V +D Sbjct: 206 PGNVTLVD 213
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 25.8 bits (56), Expect = 0.034 Identities = 12/46 (26%), Positives = 16/46 (34%) Query: 7 NDPPRQPSPKTPEPSSEDQVDISSRVQEGLKQANQRPRPHGQTPAT 52 N P TP + SS + + + R PH PAT Sbjct: 1193 NSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPAT 1238
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 30.9 bits (69), Expect = 0.005 Identities = 12/32 (37%), Positives = 15/32 (46%) Query: 207 RKAQQAKKAEEARKAEEARKAAQPAAAAQPAA 238 KA++ AE RKAEE + AA A Sbjct: 220 NKAREQAAAEAKRKAEEQARQQAAIRAANTYA 251
>PERTACTIN#Pertactin signature. Length = 922 Score = 30.5 bits (68), Expect = 0.014 Identities = 52/221 (23%), Positives = 80/221 (36%), Gaps = 9/221 (4%) Query: 175 SAAPAARFIVTESVFSMDGDRTDVARLAALAERYQAFVYLDEAHATGVLGPGGMGLAGLA 234 S APAA F+ + ++DG R A +A A V+L A P G + G A Sbjct: 214 SGAPAAVFVFGANELTVDGGHITGGRAAGVAAMDGAIVHLQRATIRRGDAPAGGAVPGGA 273 Query: 235 PDGIDLAMGTFSKALGGFGAYVAGSRA-LCDYLVNACSGFIYTTALPPAVL----GAMDA 289 G + G G +G V+ S L +V A A A + G++ A Sbjct: 274 VPGGAVPGGFGPLLDGWYGVDVSDSTVDLAQSIVEAPQLGAAIRAGRGARVTVSGGSLSA 333 Query: 290 ALDLVPTLDAERARLAASGERLRVALRGLGLDSGDSSTQIVPAIVGDEGRALALAATLEQ 349 V R L + L+ + + + V E L LA + Sbjct: 334 PHGNVIETGGGARRFPPPASPLSITLQ----AGARAQGRALLYRVLPEPVKLTLAGGAQG 389 Query: 350 RGLLAVAIRPPTVPAGTSRLRIALSAAHRDADIDRLIDGLT 390 +G + PP A + L +AL++ R R +D L+ Sbjct: 390 QGDIVATELPPIPGASSGPLDVALASQARWTGATRAVDSLS 430
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.2 bits (216), Expect = 3e-22 Identities = 32/125 (25%), Positives = 56/125 (44%), Gaps = 1/125 (0%) Query: 2 RILLVEDDTMIGESVLDCLRAEHYAVDWVKDGHAAELALRTDPYDLVLLDLGLPRRDGLT 61 IL+ +DD I + L Y V + + DLV+ D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LLRELRARKDRTPVLIATARDAVSDRIAGLDAGADDYIVKPYDVDELLARM-RALIRRSA 120 LL ++ + PVL+ +A++ I + GA DY+ KP+D+ EL+ + RAL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 GRAEP 125 ++ Sbjct: 125 RPSKL 129
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 32.2 bits (73), Expect = 0.004 Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 12/112 (10%) Query: 187 RQPEDLSPINVPDLP-------DEIRPLMQELNLLLERMRGAF--ALQKQFVGDAAHELR 237 + D++ INVPD ++I+ +QEL LE +R +F + FV Sbjct: 276 KPFADIAGINVPDTGLPNSASIEQIQSKIQELGDTLEELRDSFDGYINNAFVNQIHLNFV 335 Query: 238 SPLAALKLQLQSLRRAGDDASRRVAEE---RLAAGIERATRLVEQLLSMARH 286 P A + Q Q ++ ++ RL G ++ +L + L+ + RH Sbjct: 336 MPPQAQQQQGQGQQQQAQATAQEAVAAAAVRLLNGSDQIAQLYKDLVKLQRH 387
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 85.1 bits (210), Expect = 3e-20 Identities = 39/214 (18%), Positives = 72/214 (33%), Gaps = 39/214 (18%) Query: 117 RGEGSGFIVSNDGIILTNAHVVQGAKEVTVKLTDRREFR------------AKVLGADTQ 164 SG +V +LTN HVV L ++ + Sbjct: 101 TFIASGVVV-GKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGE 159 Query: 165 TDVAVIKIDAR--------NLPVVKIGDVNKLQVGEWVLAIGSPYGLENTATAGIVSAKG 216 D+A++K + + + + QV + + G P AT K Sbjct: 160 GDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDK-PVATMWESKGKI 218 Query: 217 RSLPDDTSVPFIQTDVAVNPGNSGGPLFNDRGEVVGINSQIYSRTGGFQGLSFSIPIDVA 276 L +Q D++ GNSG P+FN++ EV+GI+ G+ V Sbjct: 219 TYLK----GEAMQYDLSTTGGNSGSPVFNEKNEVIGIHW---------GGVPNEFNGAVF 265 Query: 277 Y--KIKDQILEHGKVQHARLGVTVQEVNQDLANS 308 +++ + ++ ++ Q N D ++ Sbjct: 266 INENVRNFLKQN--IEDIHFANDDQPNNPDNPDN 297
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 52.0 bits (124), Expect = 1e-08 Identities = 51/334 (15%), Positives = 108/334 (32%), Gaps = 4/334 (1%) Query: 168 AGVSRYKERRRETENRLSDTRENLTRVEDILRELNSQLEKLEAQAEVATRYRELQADGEK 227 + E+ +E ++ L L N L+ + + + Sbjct: 46 RSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKND 105 Query: 228 KQHALWFLKETGAREERAKKAQEMAQAQNELEAAIAGLRAGEAALESRRQAHYAASDAVH 287 K + K +A + + A N A A ++ EA + A+ Sbjct: 106 KSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALE 165 Query: 288 TAQGALYEANAQVSRLEAEIRHVVDSRNRLQARRDQLQQQIAEWNSQREHCAEQIAQAEE 347 A +A++ LEAE + + L+ + +++ + + A Sbjct: 166 GAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAA 225 Query: 348 DLAAGAARTEEARAAAEDAQAALPSVEQRVREAASGRDEMRAALARVEQNLALVAQTQRD 407 A E A + A + ++E + + E+ AL + + Sbjct: 226 RKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKT 285 Query: 408 ADRQMQALEQRRERLQQELRELHSPDPVRLEQLAGDRVAGEEQLEEAQAELATLEGKVPD 467 + + ALE + L+ + + L+ + L D A E ++ +AE LE + Sbjct: 286 LEAEKAALEAEKADLEHQSQVLN----ANRQSLRRDLDASREAKKQLEAEHQKLEEQNKI 341 Query: 468 ADAERSRAQAAAQTDAQNLARLEARLSALVKLQE 501 ++A R + + +LEA L + + Sbjct: 342 SEASRQSLRRDLDASREAKKQLEAEHQKLEEQNK 375 Score = 50.8 bits (121), Expect = 3e-08 Identities = 44/322 (13%), Positives = 99/322 (30%), Gaps = 3/322 (0%) Query: 168 AGVSRYKERRRETENRLSDTRENLTRVEDILRELNSQLEKLEAQAEVATRYRELQADGEK 227 A + + E S + L + L + LEK A + + + Sbjct: 123 ADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLE 182 Query: 228 KQHALWFLKETGAREERAKKAQEMAQAQNELEAAIAGLRAGEAALESRRQAHYAASDAVH 287 + A ++ + +++ A A A +A A + Sbjct: 183 AEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFST 242 Query: 288 TAQGALYEANAQVSRLEAEIRHVVDSRNRLQARRDQLQQQIAEWNSQREHCAEQIAQAEE 347 + A+ + LEA + + +I +++ + A E Sbjct: 243 ADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEH 302 Query: 348 DLAAGAARTEEARAAAEDAQAALPSVEQRVREAASGRDEMRAALARVEQNLALVAQTQRD 407 A + R + ++ A +E ++ A+ + ++L + ++ Sbjct: 303 QSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQ 362 Query: 408 ADRQMQALE---QRRERLQQELRELHSPDPVRLEQLAGDRVAGEEQLEEAQAELATLEGK 464 + + Q LE + E +Q LR +Q+ +L + LE Sbjct: 363 LEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEES 422 Query: 465 VPDADAERSRAQAAAQTDAQNL 486 + E++ QA + +A+ L Sbjct: 423 KKLTEKEKAELQAKLEAEAKAL 444 Score = 38.9 bits (90), Expect = 1e-04 Identities = 47/268 (17%), Positives = 103/268 (38%), Gaps = 8/268 (2%) Query: 663 QQEIENLQREIKAQQLIADQARAAVARAEVAWQQVSQAIAPARQRVAEVTRRVHDIQLEH 722 + L++ ++ + A + E ++ A + + + Sbjct: 189 EARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKI 248 Query: 723 SRLQQQAEQSGQHAARLRQDLEEIAAHEEDLRATREEAEARFEALDEELAEHQSRFADAE 782 L+ + A L + LE A + EA AL+ E A+ + + Sbjct: 249 KTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLN 308 Query: 783 MDGETLAAQAEAARARLRELERAAQEAEFAERGIQVRITDLQRNQQLAADQSQRGSVELE 842 + ++L +A+R ++LE Q+ E + + L+R+ + + ++ E + Sbjct: 309 ANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQ 368 Query: 843 QLLADLVDLDASASQAGLQDALEVRAEREEALSRARQEME-NLAALLRGADEDRLQQERT 901 +L +AS L+ L+ E ++ + +A +E LAAL + E ++ T Sbjct: 369 KLEEQNKISEASR--QSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLT 426 Query: 902 LEPRRARITELQ-----LQEQAARLAEE 924 + + +L+ L+E+ A+ AEE Sbjct: 427 EKEKAELQAKLEAEAKALKEKLAKQAEE 454
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 30.9 bits (69), Expect = 0.008 Identities = 21/55 (38%), Positives = 25/55 (45%), Gaps = 5/55 (9%) Query: 59 TPGGAPPAPVRDAAPAPAAVASPVAARSAGPGPGLRNGPPPKPAPKPEVAADAAP 113 TPG A AP +A P P SP + P P G P P P P++ DA P Sbjct: 316 TPGSAE-AP--NAQPLPEV--SPAENPANNPAPNENPGTRPNPEPDPDLNPDANP 365
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 46.9 bits (111), Expect = 2e-08 Identities = 20/73 (27%), Positives = 35/73 (47%) Query: 286 IAVARSLHRQGLGSVLLDWCEQQARERSLDGVLLEVRPSNTAAVEFYKARGYLQIGLRRG 345 IAVA+ ++G+G+ LL + A+E G++LE + N +A FY ++ + Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDTM 154 Query: 346 YYPAEKGGREDAL 358 Y E A+ Sbjct: 155 LYSNFPTANEIAI 167
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 102 bits (255), Expect = 4e-27 Identities = 38/135 (28%), Positives = 69/135 (51%), Gaps = 1/135 (0%) Query: 11 KILVVDDDPRLRDLLRRYLSEQGFNVFVAEDAKEMGKLWQREHFDLLVLDLMLPGEDGLS 70 ILV DDD +R +L + LS G++V + +A + + DL+V D+++P E+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 71 ICRRLRGGHDNTPIIMLTAKAEEIDRIVGLEMGADDYLSKPFNPRELLARI-NAILRRRG 129 + R++ + P+++++A+ + I E GA DYL KPF+ EL+ I A+ + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 130 TEEHPGAPSQENESI 144 SQ+ + Sbjct: 125 RPSKLEDDSQDGMPL 139
>PF06580#Sensor histidine kinase Length = 349 Score = 41.8 bits (98), Expect = 4e-06 Identities = 17/104 (16%), Positives = 37/104 (35%), Gaps = 22/104 (21%) Query: 351 LIENARRYG-RSTDGMAHLVMTLQAEGGMIVIEVSDRGPGIAPEDVDRLLRPFSRGEAAR 409 L+EN ++G +++ + G + +EV + G + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE------------- 309 Query: 410 TGVSGAGLGLAIVERLLKHVGG---ALRMLPREGGGLTARIELP 450 G GL V L+ + G +++ ++G A + +P Sbjct: 310 ----STGTGLQNVRERLQMLYGTEAQIKLSEKQGKV-NAMVLIP 348
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 102 bits (254), Expect = 5e-29 Identities = 60/213 (28%), Positives = 103/213 (48%), Gaps = 6/213 (2%) Query: 1 MARKTKEESQRTRDRILDAAEHVFLSKGVASTTMSDIADFAGVSRGAVYGHYKNKIDVCI 60 MARKTK+E+Q TR ILD A +F +GV+ST++ +IA AGV+RGA+Y H+K+K D+ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 AMCDRA---LGEAVSLTRVSTDGEALESLYASMRQYVQIYAEEGSVQRVLEILYLKCERS 117 + + + +GE + G+ L L + ++ E + ++EI++ KCE Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 118 DENAPLLRRRDLWERHALRTSEKLLRAAVSREDLPRALDVRLSNVYLHSLIEGVFGTICW 177 E A + + + + E+ L+ + + LP L R + + + I G+ W Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMEN--W 178 Query: 178 SDRLKGDIWPRVERML-RAAIDTLRLSPQLRTP 209 + + R ++ L P LR P Sbjct: 179 LFAPQSFDLKKEARDYVAILLEMYLLCPTLRNP 211
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.0 bits (104), Expect = 7e-07 Identities = 29/199 (14%), Positives = 58/199 (29%), Gaps = 15/199 (7%) Query: 37 IGVIVAKATPTSVASELPGRLEPY-REAEVRARVAGIVTRRLYEEGQEVARGAPLFQIDP 95 I I++ + + G+L R E++ IV + +EG+ V +G L ++ Sbjct: 70 IAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTA 129 Query: 96 -------APLQAAYDSEAAALARAQANLSAAADKLRRYADLVSDRAISERDHAESVAEER 148 Q++ R Q LS + + + + D + E V Sbjct: 130 LGAEADTLKTQSSLLQARLEQTRYQI-LSRSIELNKLPELKLPDEPYFQNVSEEEVLRLT 188 Query: 149 QARAEVALAKANLQSARLRLEYARVTSPIDGRARRALVTEGALVGEGQATPLTVVQQLDP 208 E N Q + L + + R E E Sbjct: 189 SLIKEQFSTWQN-QKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRL-----DDFSS 242 Query: 209 IYVNFSQPAAEVMQLQKQI 227 + + V++ + + Sbjct: 243 LLHKQAIAKHAVLEQENKY 261 Score = 39.0 bits (91), Expect = 3e-05 Identities = 33/231 (14%), Positives = 68/231 (29%), Gaps = 30/231 (12%) Query: 80 EGQEVARGAPLFQIDPAPLQAAYDSEAAALARAQANLSAAADKL----RRYADLVSDRAI 135 E + + L A + E A L +L + + Sbjct: 233 EKSRLDDFSSLLHKQAIAKHAVLEQENK-YVEAVNELRVYKSQLEQIESEILSAKEEYQL 291 Query: 136 SERDHAESVAEE-RQARAEVALAKANLQSARLRLEYARVTSPIDGR-ARRALVTEGALVG 193 + + ++ RQ + L L R + + + +P+ + + + TEG +V Sbjct: 292 VTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVT 351 Query: 194 EGQA--------TPLTVVQQLDPIYVNFSQPAAEV---MQLQKQIRAGALEGVAPDKMRV 242 + L V + + F ++ R G L G +V Sbjct: 352 TAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVG------KV 405 Query: 243 RLLLPDGSEYGQGGTLSFADLAVDPGTDNVTMRALFDNPDRVLLPGMYVRV 293 + + D E + G + ++++ N + L GM V Sbjct: 406 KNINLDAIEDQRLGLVFNVIISIE------ENCLSTGNKNIPLSSGMAVTA 450
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1111 bits (2874), Expect = 0.0 Identities = 540/1030 (52%), Positives = 724/1030 (70%), Gaps = 6/1030 (0%) Query: 1 MARFFIDRPVFAWVISLLIALVGLLSIRALPVAQYPDIAPPVVNIGASYPGASAKVVEEA 60 MA FFI RP+FAWV+++++ + G L+I LPVAQYP IAPP V++ A+YPGA A+ V++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTAIIEREMNGAPGLMYTSSSSDSTGWASINLTFKQGTNPDIAAVEVQNRLKAVEPRLPE 120 VT +IE+ MNG LMY SS+SDS G +I LTF+ GT+PDIA V+VQN+L+ P LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 SVRRDGVRVEKAADNIQLVVSLKSD-GSLDDMQLGELAASNVLQALRRVEGVGKVQSFGA 179 V++ G+ VEK++ + +V SD + + ASNV L R+ GVG VQ FGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 180 EAAMRIWPDPAKLTALSLTPGDIVSALRSHNARVTIGELGNQAVPQDAPLNASIVAGESL 239 + AMRIW D L LTP D+++ L+ N ++ G+LG LNASI+A Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 240 HTPEQFANIPLRAQPDGATLRLKDVARVELGGTDYMYLSRVNGMTGTGLGIKLAPGSNAV 299 PE+F + LR DG+ +RLKDVARVELGG +Y ++R+NG GLGIKLA G+NA+ Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 300 ETTRRIRETMRELAQYFPPGVSWDIPYETSTFVEISIQKVLMTLLEAVALVFCVMYLFMQ 359 +T + I+ + EL +FP G+ PY+T+ FV++SI +V+ TL EA+ LVF VMYLF+Q Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 360 NLRATLIPTLVVPVALLGTLGVMLGLGYSINVLTMFGMVLAIGILVDDAIVVVENVERIM 419 N+RATLIPT+ VPV LLGT ++ GYSIN LTMFGMVLAIG+LVDDAIVVVENVER+M Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 420 AEEGLSPHDATVKAMGQISGAIVGITVVLVSVFVPMAFFDGAVGNIYRQFAVTLAVSIAF 479 E+ L P +AT K+M QI GA+VGI +VL +VF+PMAFF G+ G IYRQF++T+ ++A Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 480 SAFLALSLTPALCASLLKPIPAGHHE-KRGFFGWFNRAFARLTTRYTARVAGVLARPVRF 538 S +AL LTPALCA+LLKP+ A HHE K GFFGWFN F YT V +L R+ Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 539 GLAYALVIGVAALLFARLPSSFLPDEDQGSFMAMVILPQGSPQAETMAVVKDVERYMMEH 598 L YAL++ +LF RLPSSFLP+EDQG F+ M+ LP G+ Q T V+ V Y +++ Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 599 EP--VQYVYSVNGFSQYGSGPNSAMFFVTLKDWKERRDASLHVDAVVKRINEAFADRKNL 656 E V+ V++VNGFS G N+ M FV+LK W+ER +AV+ R ++ Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 657 MVFALNSPPLPDLGSTSGFDFRLQDRGGLGYEALTQARQKLLAAAAEHPA-LTDVVFAGQ 715 V N P + +LG+ +GFDF L D+ GLG++ALTQAR +LL AA+HPA L V G Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 716 EEAPQLQLRIDRDKAQAMGVPIDEINTALAVMYGSDYIGDFMLNGQVRRVTVQADGKRRV 775 E+ Q +L +D++KAQA+GV + +IN ++ G Y+ DF+ G+V+++ VQAD K R+ Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 776 DVDDISRLHVRNLQGQMVPLSAFATLKWSMGPPQLNRYNGFPSFTINGSAAPGHSSGEAM 835 +D+ +L+VR+ G+MVP SAF T W G P+L RYNG PS I G AAPG SSG+AM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 836 RAMETLAAELPRGIGFDWSGQSYEERLSGNQAPVLFALSVLIVFLALAALYESWSIPLAV 895 ME LA++LP GIG+DW+G SY+ERLSGNQAP L A+S ++VFL LAALYESWSIP++V Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 896 ILVVPLGVIGALLGVTVRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDL-VRDGQGIL 954 +LVVPLG++G LL T+ ND+YF VGL+ TIGLSAKNAILIVE AKDL ++G+G++ Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 955 SATLEAARLRLRPIVMTSLAFGVGVLPLALASGAASGAQAAIGTGVLGGIITATVLAVFL 1014 ATL A R+RLRPI+MTSLAF +GVLPLA+++GA SGAQ A+G GV+GG+++AT+LA+F Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1015 VPLFFLIVGR 1024 VP+FF+++ R Sbjct: 1021 VPVFFVVIRR 1030
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 800 bits (2067), Expect = 0.0 Identities = 309/1029 (30%), Positives = 519/1029 (50%), Gaps = 29/1029 (2%) Query: 5 DLFVRRPVLALVVSTLLLLMGLRALSGLPIRQYPLTESTTITITTQYPGASPDLMQGFVT 64 + F+RRP+ A V++ +L++ G A+ LP+ QYP ++++ YPGA +Q VT Sbjct: 3 NFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVT 62 Query: 65 QPIAQSVATVEGIDYLSSSSTQ-GRSVITVRMKLNADSNKAMTEVMAKVNEVKYRLPQDA 123 Q I Q++ ++ + Y+SS+S G IT+ + D + A +V K+ LPQ+ Sbjct: 63 QVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEV 122 Query: 124 YDPVLVKSAGEATAVAYVGFSSST--MSLPALTDYLSRVVQPQLSSIDGVASVELYGGQK 181 + ++ + GF S + ++DY++ V+ LS ++GV V+L+G Q Sbjct: 123 QQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY 182 Query: 182 LAMRVWLDPDRLAARGISAGELAEALRQNNVQAAPGQAKGLYVVS------NIKVNTDLV 235 AMR+WLD D L ++ ++ L+ N Q A GQ G + +I T Sbjct: 183 -AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 236 NVAEFRDMVVKREGD-AIVRLGDVATVELGAASTDSSGLMDGEPAVYFGLNATPVGNPLV 294 N EF + ++ D ++VRL DVA VELG + + ++G+PA G+ N L Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 295 IVKRLNELLPNIKQNLPPGTSVQVPFELARFISASIDGVVHTLMEAIVIVVAVIFLCLGS 354 K + L ++ P G V P++ F+ SI VV TL EAI++V V++L L + Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 355 LRAVLIPVVTIPLSMLGGAAIMALFGFSVNLLTLLAMVLAIGLVVDDAIVVVENVHRHIE 414 +RA LIP + +P+ +LG AI+A FG+S+N LT+ MVLAIGL+VDDAIVVVENV R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 415 EGKS-PVRAALIGAREVAGPVIAMTITLAAVYAPIGLMGGLTGSLFKEFAFTLAGAVVVS 473 E K P A ++ G ++ + + L+AV+ P+ GG TG+++++F+ T+ A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 474 GVIALTLSPVMSSFLLNSHVSE-----GWMARRAEHFFNRLGQAYGRLLDVSLHHRWVTG 528 ++AL L+P + + LL +E G F+ Y + L Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 529 LVAVAVMASLPFLYNAAQRELAPVEDQSTVLTAIKSPQHANIDYVEKFGKK-WDDVMATL 587 L+ ++A + L+ P EDQ LT I+ P A + +K + D + Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 588 PEQKGRWL-ING----SDGVSNSIGGVDFVDWQKRKR---SADQIQADMQSMVNQIEGSN 639 +NG + + V W++R SA+ + + + +I Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 640 IFAFQLPP--LPGSTGGLPVQMVIMSAADYPVVYEAMENL-KQAARASGLFMVVDSDLDY 696 + F +P G+ G +++ + + + +A L AA+ + V + Sbjct: 662 VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLE 721 Query: 697 NNPVVQLKVDRAKANSLGVTMKAVGDTLAVLVGENYVNRFGMDGRSYDVIPQSLREQRIS 756 + +L+VD+ KA +LGV++ + T++ +G YVN F GR + Q+ + R+ Sbjct: 722 DTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRML 781 Query: 757 PESLARYYVKSASGAQVPLSNIVSVSMGVEPNKLTQFNQLNAATFQAIPMPGVTMGDAVQ 816 PE + + YV+SA+G VP S + +L ++N L + Q PG + GDA+ Sbjct: 782 PEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMA 841 Query: 817 FLTRQAQELPAGFSYDWQSDARQFSQEGSALMITFIFAIIVIYLVLAAQYESLRDPFIIL 876 + A +LPAG YDW + Q G+ + +V++L LAA YES P ++ Sbjct: 842 LMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVM 901 Query: 877 VSVPLSICGALIPLALGMATINIYTQIGLVTLIGLISKHGILMVEFANEMQVSHGLDRRS 936 + VPL I G L+ L ++Y +GL+T IGL +K+ IL+VEFA ++ G Sbjct: 902 LVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVE 961 Query: 937 AMEHAARIRLRPILMTTAAMVVGLIPLLFASGAGAHSRYSLGLVIVVGMLVGTLFTLFVL 996 A A R+RLRPILMT+ A ++G++PL ++GAG+ ++ ++G+ ++ GM+ TL +F + Sbjct: 962 ATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFV 1021 Query: 997 PTVYTVLAR 1005 P + V+ R Sbjct: 1022 PVFFVVIRR 1030
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 53.7 bits (129), Expect = 5e-10 Identities = 22/141 (15%), Positives = 56/141 (39%), Gaps = 7/141 (4%) Query: 105 QGELARLQAQAKNARALLERTRRLVPQQAATREQLDQAQADYDQAAGEIKRIQALIEQKR 164 + +L +++++ +A+ + +L + ++L Q + E+ + + + Sbjct: 272 KSQLEQIESEILSAKEEYQLVTQLF--KNEILDKLRQTTDNIGLLTLELAKNEERQQASV 329 Query: 165 IKAPFDGVLGVRRVH-LGQFARAGDPLVSLT-DAASVYANITLPEQALGALRMGQPVSIT 222 I+AP + +VH G + L+ + + ++ + + +G + +GQ I Sbjct: 330 IRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIK 389 Query: 223 VDAHAGR---VFEGTVTTIEP 240 V+A G V I Sbjct: 390 VEAFPYTRYGYLVGKVKNINL 410 Score = 47.1 bits (112), Expect = 6e-08 Identities = 22/124 (17%), Positives = 48/124 (38%), Gaps = 7/124 (5%) Query: 44 AVAPVLQADFPVALSGIASLEATRQVLVPAEVDGRVAQILFTPGERVRAGQLLVQLNDAP 103 + V +G + + + P E + V +I+ GE VR G +L++L Sbjct: 76 VLGQVEIV---ATANGKLTHSGRSKEIKPIE-NSIVKEIIVKEGESVRKGDVLLKLTALG 131 Query: 104 EQGELARLQAQAKNARALLERTRRLVPQQAATREQLDQAQADYDQ---AAGEIKRIQALI 160 + + + Q+ AR R + L + + + + E+ R+ +LI Sbjct: 132 AEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLI 191 Query: 161 EQKR 164 +++ Sbjct: 192 KEQF 195
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 78.1 bits (192), Expect = 4e-20 Identities = 42/204 (20%), Positives = 83/204 (40%), Gaps = 11/204 (5%) Query: 5 RLTREQSRDQTRQRLLDAAQSIFLTKGFVAASVEDIAELAGYTRGAFYSNFASKSELFLQ 64 R T+++++ +TRQ +LD A +F +G + S+ +IA+ AG TRGA Y +F KS+LF + Sbjct: 3 RKTKQEAQ-ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 65 LLKRDHENVMSDMRAIFEA--GETRQQMEDSVLHY--YSNHFRDNECFLLWMEAKLQAAR 120 + + N+ G+ + + ++H + + + K + Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 121 DPEFRIGFIACM-GELRDATTEYIRQFSERVGTPLPLPARELAIGLLALSDGMQFSFAFD 179 + + E D + ++ E P L R AI + G+ ++ F Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFA 181 Query: 180 PQNVSAETT-----ESVLAGFFRR 198 PQ+ + +L + Sbjct: 182 PQSFDLKKEARDYVAILLEMYLLC 205
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.8 bits (106), Expect = 4e-07 Identities = 18/127 (14%), Positives = 44/127 (34%), Gaps = 5/127 (3%) Query: 93 VGGKIIERKVRLGDTVKPGQVVARLDPADATKNAAAARAQLSAAQ-----HQLDYAKQQL 147 + E V+ G++V+ G V+ +L A + ++ L A+ +Q+ +L Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIEL 162 Query: 148 DRDRAQARENLIAANQLEQTRNAYASALAQRDQAAQQAALSADQLNYTTLVADHAGVITA 207 ++ + + + ++L + + Q +LN A+ V+ Sbjct: 163 NKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLAR 222 Query: 208 EQADTGQ 214 Sbjct: 223 INRYENL 229 Score = 33.6 bits (77), Expect = 0.001 Identities = 25/198 (12%), Positives = 61/198 (30%), Gaps = 28/198 (14%) Query: 120 ADATKNAAAARAQLSAAQHQLDYAKQQLDRDRAQARENLIAANQLEQTRNAYASALAQRD 179 +A ++QL + ++ AK++ + + + Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN---------EILDKLRQTTDNIG 312 Query: 180 QAAQQAALSADQLNYTTLVADHAGVITAEQADT-GQNVAAGQAVYNLAWSGD---VDALC 235 + A + ++ + + A + + + T G V + + + D V AL Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTAL- 371 Query: 236 DVPESVLAGLAIGQRATVTLAPLPGKTFSAV---LREIAPAADPQSRT---YRAKLTLES 289 V + + +GQ A + + P + + ++ I A R + +++E Sbjct: 372 -VQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEE 430 Query: 290 PSPEVRL-------GMTA 300 GM Sbjct: 431 NCLSTGNKNIPLSSGMAV 448 Score = 29.4 bits (66), Expect = 0.025 Identities = 19/113 (16%), Positives = 40/113 (35%), Gaps = 7/113 (6%) Query: 96 KIIERKVRLGDTVKPGQVVARLDPADATKNAAAARAQLSAAQHQLDYAKQQLDRDRAQ-- 153 + IE + + + + + + Q S Q+Q + LD+ RA+ Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERL 217 Query: 154 ----ARENLIAANQLEQTRNAYASALAQRDQAAQQAALSADQLNYTTLVADHA 202 +++E++R S+L QA + A+ + Y V + Sbjct: 218 TVLARINRYENLSRVEKSRLDDFSSLLH-KQAIAKHAVLEQENKYVEAVNELR 269
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 472 bits (1217), Expect = e-152 Identities = 241/1047 (23%), Positives = 442/1047 (42%), Gaps = 62/1047 (5%) Query: 22 LSAWALRHQPLVIFLITLVTLFGVLSYSRLAQSEDPPFTFRVMVIKTLWPGATSQQVQEQ 81 ++ + +R L ++ + G L+ +L ++ P + + +PGA +Q VQ+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 82 VTDRIAKKLQETPSTDFLRSYS-RPGESLIFFTMKDSAPASEVANEWYQVRKKVGDIGAT 140 VT I + + + ++ S S G I T + QV+ K+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQV---QVQNKLQLATPL 117 Query: 141 LPQGVQGP-FFNDEFGDVYTNIYTLAGDG--FSPAQLRDYAD-NLRTVLLRVPGVAKVDY 196 LPQ VQ ++ Y + D + + DY N++ L R+ GV V Sbjct: 118 LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL 177 Query: 197 FGEQPEHVYIEISNTQLTRLGVSPQQIAEAINSQNAVASAGTLTTADD------RVFVRP 250 FG Q + I + L + ++P + + QN +AG L + Sbjct: 178 FGAQYA-MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIA 236 Query: 251 SGQFQDTRALAETLIRVN--GKSIRLGDIATIHRGYDDPPAEQMRTRGEPVLGIGITMQP 308 +F++ + +RVN G +RL D+A + G ++ R G+P G+GI + Sbjct: 237 QTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENY-NVIARINGKPAAGLGIKLAT 295 Query: 309 GQDVVHLGKALEAKFGELKARLPAGLTLTEVSSMPKAVSFSVDEFLRSVAEAVAIVLIVS 368 G + + KA++AK EL+ P G+ + V S+ E ++++ EA+ +V +V Sbjct: 296 GANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVM 355 Query: 369 LVSLG-LRTGMVVVISIPVVLAVTALFMDMFGIGLHKVSLGTLVLALGLLVDDAIIAVEM 427 + L +R ++ I++PVVL T + FG ++ +++ +VLA+GLLVDDAI+ VE Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN 415 Query: 428 MA-VKLEQGWSRARAAAFAYTSTAFPMLTGTLVTVAGFLPIALAKSSTGEYTRSIFQVSA 486 + V +E A + + ++ +V A F+P+A STG R Sbjct: 416 VERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIV 475 Query: 487 IALITSWFAAVVLIPLLGYRMLPERKREAHLPDDHEHDIYNTRFYQRLRGW---VAWCVD 543 A+ S A++L P L +L E H +NT F + + V + Sbjct: 476 SAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILG 535 Query: 544 RRWRVLLATVLVFILSMAGFGLVPQQFFPSSDRTELLVDVRLQEGASFAATLRQVERLEK 603 R LL L+ + F +P F P D+ L ++L GA+ T + ++++ Sbjct: 536 STGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTD 595 Query: 604 VL--DGRPEIAHSVSFVGTGAPRFYLPLDQQLATPNFAQIVITANSVEDR---EKLAHWL 658 + + + + G N ++ E+R E A + Sbjct: 596 YYLKNEKANVESVFTVNGFSFSG---------QAQNAGMAFVSLKPWEERNGDENSAEAV 646 Query: 659 EPVLREQFPAIRSRLSRLENGPPV-------GF----QVQFRVSGDKIPEVRQVAEKVAA 707 + + IR N P + GF Q + D + + R +AA Sbjct: 647 IHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAA 706 Query: 708 EVRADSRSVNVQFDWDEPSERSVRFDIDQQKAREVGVSSNDISSFLAMTLSGYTVTQYRE 767 + A SV D + ++DQ+KA+ +GVS +DI+ ++ L G V + + Sbjct: 707 QHPASLVSVRPNGLEDTAQ---FKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFID 763 Query: 768 RDKLINVSLRAPDSERIDPGRLATLAMPTPNG-PVPLGSLGQVRYGLEYGVIWERDRQPT 826 R ++ + ++A R+ P + L + + NG VP + + + + P+ Sbjct: 764 RGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPS 823 Query: 827 ITVQADVTAGAQGIDVTHAIDRKLDALRAELPVGYRIEVGGPVEESAKGQSSINAQMPIM 886 + +Q + G D ++ L ++LP G + G + + A + I Sbjct: 824 MEIQGEAAPGTSSGDAMALMEN----LASKLPAGIGYDWTGMSYQERLSGNQAPALVAIS 879 Query: 887 VVAVLTLLMVQLQSFARVLMVVLTAPLGLIGVVAALLLFGKPFGFVAMLGVIAMFGIIMR 946 V V L +S++ + V+L PLG++GV+ A LF + M+G++ G+ + Sbjct: 880 FVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAK 939 Query: 947 NSVILVDQIEQDISA-GHKRVDAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFG---- 1001 N++++V+ + + G V+A + A R RPI +T+ A +L ++PL SN G Sbjct: 940 NAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQ 999 Query: 1002 -PMATALMGGITSATVLTLFFLPALYA 1027 + +MGG+ SAT+L +FF+P + Sbjct: 1000 NAVGIGVMGGMVSATLLAIFFVPVFFV 1026 Score = 93.0 bits (231), Expect = 3e-21 Identities = 63/335 (18%), Positives = 133/335 (39%), Gaps = 23/335 (6%) Query: 726 SERSVRFDIDQQKAREVGVSSNDISSFL--------AMTLSGYTVTQYRERDKLINVSLR 777 ++ ++R +D + ++ D+ + L A L G ++ + I R Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 778 APDSERIDPGRLATLAMPTPNGPVPLGSLGQVRYGLE-YGVIWERDRQPTITVQADVTAG 836 + E TL + + V L + +V G E Y VI + +P + + G Sbjct: 240 FKNPEEFGK---VTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATG 296 Query: 837 AQGIDVTHAIDRKLDALRAELPVGYRIEVGGPVEESAKGQSSINA---QMPIMVVAVLTL 893 A +D AI KL L+ P G ++ P + + Q SI+ + ++ V + Sbjct: 297 ANALDTAKAIKAKLAELQPFFPQGMKVLY--PYDTTPFVQLSIHEVVKTLFEAIMLVFLV 354 Query: 894 LMVQLQSFARVLMVVLTAPLGLIGVVAALLLFGKPFGFVAMLGVIAMFGIIMRNSVILVD 953 + + LQ+ L+ + P+ L+G A L FG + M G++ G+++ +++++V+ Sbjct: 355 MYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVE 414 Query: 954 QIEQDISAGH-KRVDAIVGATVRRFRPITLTAAAAVLALIPLL-----RSNFFGPMATAL 1007 +E+ + +A + + + A IP+ + + + Sbjct: 415 NVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITI 474 Query: 1008 MGGITSATVLTLFFLPALYAAWFRVRHDEREEPEG 1042 + + + ++ L PAL A + E E +G Sbjct: 475 VSAMALSVLVALILTPALCATLLKPVSAEHHENKG 509
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.1 bits (73), Expect = 0.006 Identities = 37/206 (17%), Positives = 68/206 (33%), Gaps = 20/206 (9%) Query: 235 DALQADQDAATLEASLPGLRAQ---WQATRHALAVLMGRSPDQAPPDLAFAMIAVPEEV- 290 AL A+ D ++SL R + +Q ++ L + P + F ++ E + Sbjct: 128 TALGAEADTLKTQSSLLQARLEQTRYQILSRSIE-LNKLPELKLPDEPYFQNVSEEEVLR 186 Query: 291 -PVLVPSELLAARPDIHIAEAVLRAAAADVGVATAQLFPSLSLSASMG-----------K 338 L+ + + + E L A+ A++ +LS K Sbjct: 187 LTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHK 246 Query: 339 GGFSWPTALSGAGSIWAVGASLTQPIFHGGALLAERSAAKERYEAAVLQYKQTVLTALRD 398 + L L + +E +AKE Y+ +K +L LR Sbjct: 247 QAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQ 306 Query: 399 VADTLAQLEADGQALASAEASRRAAE 424 D + L LA E ++A+ Sbjct: 307 TTDNIGLLT---LELAKNEERQQASV 329
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 360 bits (925), Expect = e-122 Identities = 132/397 (33%), Positives = 197/397 (49%), Gaps = 30/397 (7%) Query: 128 ALEVGTFDAEAQS-DLRDMIVLVEAALRVTRLEAETRALRVARGALPADSALADDSEILG 186 A E G +D + DL ++I ++ AL + G ++G Sbjct: 93 ASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGM-----------PLVG 141 Query: 187 QSEAIARLLHEIEVVADSELPILLLGETGVGKELFAHRVHRQSRRRGKPLVHVNCAALPE 246 +S A+ + + + ++L +++ GE+G GKEL A +H +RR P V +N AA+P Sbjct: 142 RSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPR 201 Query: 247 SLAESELFGHAKGAFSGALTERPGRFEAANGGTLFLDEVGELPLAVQAKLLRTLQNGEIQ 306 L ESELFGH KGAF+GA T GRFE A GGTLFLDE+G++P+ Q +LLR LQ GE Sbjct: 202 DLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYT 261 Query: 307 RLGDDRPRTVDVRIVAATNRDLRDRVRQGDFRADLYHRLSVYPVPIPPLRKRGRDVLLLA 366 +G P DVRIVAATN+DL+ + QG FR DLY+RL+V P+ +PPLR R D+ L Sbjct: 262 TVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLV 321 Query: 367 GRYLELNRARLGLRSLRLSPEAEDMLSRYRWPGNVRELEHVISRAAIKAVSHGAHRNEIV 426 +++ + GL R EA +++ + WPGNVRELE+++ R R I Sbjct: 322 RHFVQQAE-KEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIE 380 Query: 427 TLGPGLLDLDDVAMPAPPPEAPALPAGAAQPLR-----------------VAVDACQRQA 469 + + A + ++ + +R + + Sbjct: 381 NELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPL 440 Query: 470 IRRALQAHQGSWAGAARALDIDSSNLHKLARRLGLKD 506 I AL A +G+ AA L ++ + L K R LG+ Sbjct: 441 ILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSV 477
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.0 bits (187), Expect = 9e-17 Identities = 24/115 (20%), Positives = 54/115 (46%), Gaps = 5/115 (4%) Query: 412 TRKAVLLVEDNRMVGEVVSTLLTDLGQDLTWATDAESALGMLQERQGRFDIAILDIVLPG 471 T +L+ +D+ + V++ L+ G D+ ++A + + G D+ + D+V+P Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWI--AAGDGDLVVTDVVMPD 59 Query: 472 MDGVQLAEMIKAQWPAIRVVLATGYSE---ALAGRDAGALEVMQKPYSIEALTRL 523 + L IK P + V++ + + A+ + GA + + KP+ + L + Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGI 114
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 74.5 bits (183), Expect = 8e-19 Identities = 28/119 (23%), Positives = 48/119 (40%), Gaps = 2/119 (1%) Query: 2 TILLADDNQDAVETLAEILRLDHHQVHTAFEGRTALALAQAHRPDIVLLDISMPELDGYT 61 TIL+ADD+ L + L + V T A D+V+ D+ MP+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LCQRLRREPWAAGLVIVALSGYGSPQDLERGRIAGFDRYFTKPADPGELLDYLNRCGGH 120 L R+++ L ++ +S + + G Y KP D EL+ + R Sbjct: 65 LLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 123 bits (309), Expect = 3e-36 Identities = 79/256 (30%), Positives = 122/256 (47%), Gaps = 10/256 (3%) Query: 4 LTGKVAIITGASSGIGYEAAKLFAREGASLVVVARRQAELEHLVAAIEADGGHAVPLAGD 63 + GK+A ITGA+ GIG A+ A +GA + V +LE +V++++A+ HA D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 64 VRDEAVAEAAVTLAERRFGGLDIAFNNAGMTGGALPLHQVPPDAWRQILDTNLSSAFLGA 123 VRD A + ER G +DI N AG+ +H + + W N + F + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPG-LIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 124 RHQIPAMLRRGGGSLVFTSTFVGHTAGFPGMGAYAASKAGLIGLTQAIAAEYGAQGIRAN 183 R M+ R GS+V + M AYA+SKA + T+ + E IR N Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRT-SMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 184 ALLPGGTDTPMGRA--SMDSPEARRYIESLHA------LKRLASPAEIARSALYLASDAS 235 + PG T+T M + + ++ + SL LK+LA P++IA + L+L S + Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 236 SFTTGTALLVDGGVSI 251 T L VDGG ++ Sbjct: 244 GHITMHNLCVDGGATL 259
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 89.3 bits (221), Expect = 1e-23 Identities = 66/250 (26%), Positives = 112/250 (44%), Gaps = 13/250 (5%) Query: 4 RIAYVTSGMGHTGTAICQALHHAGHRVIA-GCGPRSSRKDHWLKEQKSLGYDFIASEGDA 62 +IA++T G A+ + L G + A P K + K+ A D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEK--VVSSLKAEARHAEAFPADV 66 Query: 63 TDWASTEAAFAKVRREVGEIDVLVNNAGAMLDMRFRQMSHADWSAVLRSNLDTLFNSTKQ 122 D A+ + A++ RE+G ID+LVN AG + +S +W A N +FN+++ Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 123 VVDGMAERGWGRIINIGSVAAEKGQIGQINYATAKGAVIGFTRSLAQEVAARGVTVNLVS 182 V M +R G I+ +GS A + YA++K A + FT+ L E+A + N+VS Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 183 PG----------FIADDTVKAFPPVLLDRIIESVPVGRLGTAEDLAGLCAWLASDEAAFV 232 PG + ++ + L+ +P+ +L D+A +L S +A + Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 233 TGANYAINGG 242 T N ++GG Sbjct: 247 TMHNLCVDGG 256
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 109 bits (275), Expect = 4e-28 Identities = 67/343 (19%), Positives = 106/343 (30%), Gaps = 65/343 (18%) Query: 56 WGLSAMNAQYAYARGLSGAGVKLGAVDSGYLPSHREFASRGIIALSVKGTYMNDGEQLDG 115 G+ + A + + G GVK+ +D+G H + +R Sbjct: 24 RGVEMIQAPAVWNQT-RGRGVKVAVLDTGCDADHPDLKAR-------------------- 62 Query: 116 SKLAWRAGEAFDRAGAYVDKTDLTKRIGANDN-HGNHVSGTIAAAKNGQGMMGVSFGSQY 174 + D + I + N HG HV+GTIAA +N G++GV+ + Sbjct: 63 ----------IIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATENENGVVGVAPEADL 112 Query: 175 YTTNSNGTDSSRYGSNMDYNYFKAAYGNLAAAGVRVINSSWGSPPTADNYDTLSSFTQAY 234 S + V +I+ S G P Sbjct: 113 LIIKVLNKQGSGQYDWI-----IQGIYYAIEQKVDIISMSLGGPEDVP------------ 155 Query: 235 LRLNGAGKKTWLDAAADVSLQYGVLHVWANGNAGVAHASTRAGLPYFRLELEKYWITATG 294 L A ++ +L + A GN G T I+ Sbjct: 156 ----------ELHEAVKKAVASQILVMCAAGNEGDGDDRT---DELGYPGCYNEVISVGA 202 Query: 295 LKPSGDQGFNKCGLAKYWCLAAPGYNILSANVTGDDKYKESNGTSMSAPHVTGALGILME 354 + L APG +ILS G KY +GTSM+ PHV GAL ++ + Sbjct: 203 INFDRHAS-EFSNSNNEVDLVAPGEDILSTVPGG--KYATFSGTSMATPHVAGALALIKQ 259 Query: 355 RYPYLGNEEIRTILLTTASHRGTGPADTPNEVFGWGVPDLRKG 397 ++ L + T P ++ G G+ L Sbjct: 260 LANASFERDLTEPELYAQLIKRTIPLGNSPKMEGNGLLYLTAV 302
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 8e-23 Identities = 45/143 (31%), Positives = 65/143 (45%), Gaps = 4/143 (2%) Query: 2 RILVIEDDEDLADALVRRLRRLGHAVDCQKDGLSADGVLQYETFDLVILDIGLPRMSGFE 61 ILV +DD + L + L R G+ V + + + DLV+ D+ +P + F+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 ILHRLRDRGSKTPVLALTARIDIEDRVHALDTGADDYLAKPFDFRELEARCRALL----R 117 +L R++ PVL ++A+ + A + GA DYL KPFD EL L R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 118 RPSVQAAGVLRFGELVIDSAARQ 140 RPS LV SAA Q Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQ 147
>PF06580#Sensor histidine kinase Length = 349 Score = 42.9 bits (101), Expect = 2e-06 Identities = 20/103 (19%), Positives = 41/103 (39%), Gaps = 22/103 (21%) Query: 367 LIDNALRHGAS---ADGHIDVRLERDDAGWRITVADQGPGISAALAQSAFERFSRGPNPR 423 L++N ++HG + G I ++ +D+ + V + G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSL---------------ALKNT 307 Query: 424 TPGAGLGLSIIKRVVDIHHG---RLSLSNRPGGGLEAVVLLPA 463 G GL ++ + + +G ++ LS + G A+VL+P Sbjct: 308 KESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKV-NAMVLIPG 349
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 50.6 bits (121), Expect = 2e-09 Identities = 28/130 (21%), Positives = 44/130 (33%), Gaps = 20/130 (15%) Query: 1 MRILVIGGTGFIGRHLIARLSGGQHQILV---------PTRRYGQGRELQILPTVTLLAS 51 M+ LV G GFIG H+ RL HQ++ + + + EL P Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQAR-LELLAQPGFQFHKI 59 Query: 52 DVHDDDALDRLARDC--DVVVNLVGILHGNAGRPYGSDFAQAHVHLP----QRIARACRR 105 D+ D + + L + V Y + A+ I CR Sbjct: 60 DLADREGMTDLFASGHFERVFISP----HRLAVRYSLENPHAYADSNLTGFLNILEGCRH 115 Query: 106 QGVRRLLHVS 115 ++ LL+ S Sbjct: 116 NKIQHLLYAS 125
>PERTACTIN#Pertactin signature. Length = 922 Score = 33.2 bits (75), Expect = 0.003 Identities = 23/66 (34%), Positives = 25/66 (37%), Gaps = 7/66 (10%) Query: 82 QWRLWSRVLPAEAKLQRFNGRRPPPRGTQRPPPPPPPPPSAQIQGPPLPPEMRDEHEVEQ 141 QW L P K P G Q P PP PP Q PP PP+ + E Q Sbjct: 559 QWSLVGAKAPPAPK-------PAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQ 611 Query: 142 ERAERE 147 A RE Sbjct: 612 PPAGRE 617
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.4 bits (240), Expect = 3e-25 Identities = 47/135 (34%), Positives = 73/135 (54%), Gaps = 1/135 (0%) Query: 9 TKLLVVDDDPALRQLLADYLNRHGYDTLLAPDASDLPSRITRYAPDLLVLDRMLPGGDGA 68 +LV DDD A+R +L L+R GYD + +A+ L I DL+V D ++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 69 DACRRLREQGEDIPVILLTARDEAVDRIIGLEAGADDYVGKPFDPRELLARIE-AVLRRK 127 D R+++ D+PV++++A++ + I E GA DY+ KPFD EL+ I A+ K Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 128 RGPSALTKDAPVAFG 142 R PS L D+ Sbjct: 124 RRPSKLEDDSQDGMP 138
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 59.1 bits (143), Expect = 2e-11 Identities = 36/238 (15%), Positives = 61/238 (25%), Gaps = 40/238 (16%) Query: 220 LAEGTFGYSSSLGRLNRMDPSATSGAVDYGASVGNSTVRYGLTPVLTLEGQMQSAPSLTT 279 EG YS + G A ST+ +GL T+ G Q A Sbjct: 369 QREGHTRYSITAGEYRS------GNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRA 422 Query: 280 RGMGTTYTAGEYGTFQAGATQSSFDAA-----SAWRYRFGYS------------------ 316 G G G TQ++ RF Y+ Sbjct: 423 FNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYS 482 Query: 317 ----VDVADAVNLGYTNEQIGAGFGDLSTYSGGVAAAPQTRN-----TLTAGVPITGWGT 367 + AD I G + N LT + T Sbjct: 483 TSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTST 542 Query: 368 LSGTYSGL-HEGSALAEQRLGLSHSM-FVAPKVKLAVGADRDIISGNYEWRANLSMPV 423 L + S + G++ +++ + F L+ ++ + L++ + Sbjct: 543 LYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNI 600
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.1 bits (75), Expect = 0.002 Identities = 28/116 (24%), Positives = 40/116 (34%), Gaps = 16/116 (13%) Query: 161 RPAQVIDTAPPNDVATPVPSVPAAAVEIA-------PAPTPAAE-------AQVDKAADK 206 + + PN++ VPSVP+ EIA P P PA A+ K K Sbjct: 990 QTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESK 1049 Query: 207 TTDKSADKAAAEPLPERAAASTTSAPSPTPAAPQSSSALVITKPLRSGQRVYARHT 262 T +K+ A R A A S A Q++ + Q + T Sbjct: 1050 TVEKNEQDATETTAQNREVAK--EAKSNVKANTQTNEVAQSGSETKETQTTETKET 1103
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 57.5 bits (139), Expect = 3e-11 Identities = 32/227 (14%), Positives = 68/227 (29%), Gaps = 20/227 (8%) Query: 97 LTQQNELRNTQAALQTRRAERAAKVATLKQAELAFRRQRQMLAADASSREAFESAEATLG 156 ++ + + E + L+Q E ++L+A + + + Sbjct: 248 AIAKHAVLEQENKYVEAVNELRVYKSQLEQIE------SEILSAKEEYQLVTQLFKNE-- 299 Query: 157 VTRADIAALDAQIVQAEIEVDKAKVNLGYTRIVSPIDGVVVAV-VTKEGQTVNAIQSAPT 215 + I +E+ K + + I +P+ V + V EG V + Sbjct: 300 -ILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE--TL 356 Query: 216 IIKVAQVATMTIKAQISEADVTRVKPGLPVYFTILGEPDHRY-HATLRAVEPAPDSIQKD 274 ++ V + T+ + A + D+ + G + P RY + + D+I+ Sbjct: 357 MVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQ 416 Query: 275 DAATSLTSSSSTSTSAAVYYNGLFDVPNPDEKLRISMTAQVSIVLGE 321 S + N + L M I G Sbjct: 417 RLGLVFNVIISIEENCLS-------TGNKNIPLSSGMAVTAEIKTGM 456 Score = 52.5 bits (126), Expect = 2e-09 Identities = 28/180 (15%), Positives = 64/180 (35%), Gaps = 17/180 (9%) Query: 1 MKKPRSKVQRYVLIAVVLLIIAFGVRAAFFSSPPPPTFAVAEVVRGNLEDSVLASGTMDA 60 ++ P S+ R V ++ ++ + + G +E A+G + Sbjct: 49 IETPVSRRPRLVAYFIMGFLVIAFILSVL----------------GQVEIVATANGKLTH 92 Query: 61 IERV-SVGAQATGQLKSLKVALGDRVTRGQLVAEIDDLTQQNELRNTQAALQTRRAERAA 119 R + +K + V G+ V +G ++ ++ L + + TQ++L R E+ Sbjct: 93 SGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTR 152 Query: 120 KVATLKQAELAFRRQRQMLAADASSREAFESAEATLGVTRADIAALDAQIVQAEIEVDKA 179 + EL + ++ + E + + + Q Q E+ +DK Sbjct: 153 YQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKK 212
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 50.6 bits (121), Expect = 4e-09 Identities = 67/320 (20%), Positives = 117/320 (36%), Gaps = 9/320 (2%) Query: 34 GTLVAVFAVLPMLFSVRAGRWVDRVGIVRPLVTGTTLVAVGTALPFLSQTQFALLVASCC 93 G L+A++A++ + G DR G L+ AV A+ + + L + Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 94 IGIGFMLHQVATQDLLGHAEPTQRLRNFSLMSLALAGSGFSGPLIAGLAIDHLGTRLAF- 152 GI VA + + +R R+F MS +GP++ GL F Sbjct: 106 AGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFF 164 Query: 153 --GLLTLGPLLSAGGLYALRHQLKAVDSQLAGTKEAQRRRVTELLAVPALRRILMVNTIL 210 L L+ L H+ + + R + V A + L Sbjct: 165 AAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQL 224 Query: 211 SGAWDTHLFVVPIFGV-AIGLSATTIGVILASFAAATFIIRLVL-PLIQRRVRSWTLVRV 268 G L+V IFG ATTIG+ LA+F + + ++ + R+ + + Sbjct: 225 VGQVPAALWV--IFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALML 282 Query: 269 AMATAAIDFMLYPLFTDVGVLIVLSFILGLALGCCQPSMLSLLHQHSPPGRAAEAVGLRM 328 M ++L F G + +L + G P++ ++L + R + G Sbjct: 283 GMIADGTGYILL-AFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLA 341 Query: 329 ALINGSQVSLPLTFGALGAV 348 AL + + + PL F A+ A Sbjct: 342 ALTSLTSIVGPLLFTAIYAA 361
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 28.4 bits (63), Expect = 0.015 Identities = 9/33 (27%), Positives = 16/33 (48%) Query: 15 TALGRYATGVTVVTTADLDGAPIGLTVSSFNSV 47 T L ++G++ T L GAP+ V + + Sbjct: 373 TVLASVSSGISAAATTSLVGAPVSALVGAVTGI 405
>PF04183#IucA / IucC family Length = 580 Score = 32.9 bits (75), Expect = 0.002 Identities = 12/71 (16%), Positives = 26/71 (36%), Gaps = 1/71 (1%) Query: 48 SEVIHAGIYYPAGSLKARLCVRGKHLLYAYCAERGI-PHKRLGKLIVATSTEQAAQLEGI 106 SE+ + +++ R C+ + + AERGI + + + E + Sbjct: 19 SELEYEQVFHAESQGDDRYCINLPGAQWRFIAERGIWGWLWIDAQTLRCADEPVLAQTLL 78 Query: 107 AQRARANGVDD 117 Q + + D Sbjct: 79 MQLKQVLSMSD 89
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 430 bits (1106), Expect = e-146 Identities = 175/540 (32%), Positives = 287/540 (53%), Gaps = 46/540 (8%) Query: 1 MLKRMILATALSLGLAAGAQAAPNWPNVPYSYYARDENLQTLLREFAGGFSLSLQIGPNV 60 KR++ T L L + AQ W +PY Y A+ E+L+ LL +F + ++ + + Sbjct: 8 FFKRVLTGTLLLLSSYSWAQELD-WLPIPYVYVAKGESLRDLLTDFGANYDATVVVSDKI 66 Query: 61 TGTVNGKFNANTPTEFMDRLGGVYGFNWFVYAGTLFVSRTNDMKTRSVSAMGSSISALRQ 120 V+G+F + P +F+ + +Y W+ L++ + +++ +R + S + L+Q Sbjct: 67 NDKVSGQFEHDNPQDFLQHIASLYNLVWYYDGNVLYIFKNSEVASRLIRLQESEAAELKQ 126 Query: 121 ALQQLGVLDPRFGWGELPDQGIALVSGPPGYVDLVERTVAAL-------PMGAGGQQVAV 173 ALQ+ G+ +PRFGW + VSGPP Y++LVE+T AAL G + + Sbjct: 127 ALQRSGIWEPRFGWRPDASNRLVYVSGPPRYLELVEQTAAALEQQTQIRSEKTGALAIEI 186 Query: 174 FRLKHASVNDRTISYRDQKVVTPGLSTVLRNLITGGGGGANNETLAAIAAPLRDNPPAFP 233 F LK+AS +DRTI YRD +V PG++T+L+ ++ Sbjct: 187 FPLKYASASDRTIHYRDDEVAAPGVATILQRVL--------------------------- 219 Query: 234 QVAGDGAAAPAGPAGNQPAAPASTGKSGLRLREPTVQADARLNAIIVQDIPDRIPIYRSL 293 A NQ A+T S + V+AD LNAIIV+D P+R+P+Y+ L Sbjct: 220 ----SDATIQQVTVDNQRIPQAATRASA----QARVEADPSLNAIIVRDSPERMPMYQRL 271 Query: 294 IEQLDLPSTLVEIEAMIVDVNSDLVSELGVTWGARAGSTTFGYGNLGLGPSGGLPLESGA 353 I LD PS +E+ IVD+N+D ++ELGV W R G T + + +G + Sbjct: 272 IHALDKPSARIEVALSIVDINADQLTELGVDW--RVGIRTGNNHQVVIKTTGDQSNIASN 329 Query: 354 ALSPGTIGVSVGNTLAARLRALQTKGQANILSQPSILTADNLGAMIDLSDTFYIQTRGER 413 + + L AR+ L+ +G A ++S+P++LT +N A+ID S+T+Y++ G+ Sbjct: 330 GALGSLVDARGLDYLLARVNLLENEGSAQVVSRPTLLTQENAQAVIDHSETYYVKVTGKE 389 Query: 414 VATVTPVTVGTSLRVTPRHIESKNGARVELTVDIEDGR-IQEERQIDNLPTVRKSNISTL 472 VA + +T GT LR+TPR + + + + L + IEDG I+ +PT+ ++ + T+ Sbjct: 390 VAELKGITYGTMLRMTPRVLTQGDKSEISLNLHIEDGNQKPNSSGIEGIPTISRTVVDTV 449 Query: 473 AIVGNNQTLLIGGYNSSQNSEQVDKVPILGDIPGLGLLFSNKSKTVQRRERLFLIRPKVV 532 A VG+ Q+L+IGG + S + KVP+LGDIP +G LF KS+ +R RLF+I P+++ Sbjct: 450 ARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYIGALFRRKSELTRRTVRLFIIEPRII 509
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 827 bits (2139), Expect = 0.0 Identities = 286/1033 (27%), Positives = 509/1033 (49%), Gaps = 25/1033 (2%) Query: 4 SRLFILRPVATTLSMVAILIAGFIAYRMLPVSALPEVDYPTIQVTTLYPGASPDVMTSLV 63 + FI RP+ + + +++AG +A LPV+ P + P + V+ YPGA + V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 64 TSPLERQFGQMPGLNQMSSTS-SGGASVITMQFNLTLPLDVAEQQVQAAINAASNLLPSD 122 T +E+ + L MSSTS S G+ IT+ F D+A+ QVQ + A+ LLP + Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 123 LPVPPTYNKVNPADAAVLTLAITS--PTMPLPQVRDLVDTRVAQKLSQIPGVGLVSVAGG 180 + + + ++ S P + D V + V LS++ GVG V + G Sbjct: 122 VQQQGIS-VEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QRPAVRVQVNPQALAANGLGLTDLRAAVVGANVNQPKGNLDGPL------RSTTINANDQ 234 Q A+R+ ++ L L D+ + N G L G + +I A + Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 235 LKSPTDYNDLII-AYKNNAPLRLSDVARAVEGAEDTRQAAWAGDKPAILLNIQRQPGANV 293 K+P ++ + + + + +RL DVAR G E+ A KPA L I+ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 294 IDVVNRIQALLPQLRAALPATLDVTVVSDRTQTIRDSVADVQFEMLLAVALVVMVTFVFL 353 +D I+A L +L+ P + V D T ++ S+ +V + A+ LV +V ++FL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 354 RSLTATLIPSVVVPLSLVGTFGIMYLAGFSINNLTLMALTIATGFVVDDAIVMIENIARH 413 +++ ATLIP++ VP+ L+GTF I+ G+SIN LT+ + +A G +VDDAIV++EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 414 I-EEGETPLQAALKGAQQIGFTLISLTFSLIAVLIPLLFMTEVVGRLFREFAITLAVSIL 472 + E+ P +A K QI L+ + L AV IP+ F G ++R+F+IT+ ++ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 473 ISLVVSLTLTPMMCARLLRAESEQKH---GRFHQVTGAFIDRTIAAYDRMLQKVLRHQPL 529 +S++V+L LTP +CA LL+ S + H G F D ++ Y + K+L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 530 TLLVALATFALTVLLYILVPKGFFPQQDTGLIQAITQAPQSISFTAMAERQQAAARLAL- 588 LL+ A V+L++ +P F P++D G+ + Q P + + L Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 589 -EDPDVQAVSSFIGVDGSNATLSAGRMQIALKPQAERNGDLRTVMARLQQAFGKQDGLTV 647 E +V++V + G S +AG ++LKP ERNGD + A + +A + + Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 648 -YMQPVQDLTIEDRVSRTQYQMTL---SNPDLKVLSEWTPKLIDRLRQVPG-LKDVTDDL 702 ++ P I + + T + L + L++ +L+ Q P L V + Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 703 QDDGLQTWVEIDRDAASRLGITAAVVDEALYDAFGQRLISTIFTQSNQYRVVLEVQPQFQ 762 +D Q +E+D++ A LG++ + +++ + A G ++ + ++ ++ +F+ Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 763 MNPAALGQIHVPTSTGAQVPLSSIARITEGKTVLAVNRLDQFPMVTVSFNLAPGASLSAA 822 M P + +++V ++ G VP S+ + R + P + + APG S A Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 823 VEAITAAEAEIGMPASVETRFQGAALAFQNSLSSTLWLILAAIVTMYIVLGVLYESYIHP 882 + + ++ +PA + + G + + S + L+ + V +++ L LYES+ P Sbjct: 840 MALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIP 897 Query: 883 ITILSTLPSAGVGALLALLISGTELDMIGIIGIILLIGIVKKNAIMMIDFALDAERKRGL 942 ++++ +P VG LLA + + D+ ++G++ IG+ KNAI++++FA D K G Sbjct: 898 VSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGK 957 Query: 943 SPRAAIHEAALLRFRPILMTTLAALFGALPLMLSTGTGAELRQPLGLVMVGGLLLSQVLT 1002 A A +R RPILMT+LA + G LPL +S G G+ + +G+ ++GG++ + +L Sbjct: 958 GVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLA 1017 Query: 1003 LFTTPVIYLMFDR 1015 +F PV +++ R Sbjct: 1018 IFFVPVFFVVIRR 1030
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.3 bits (102), Expect = 1e-06 Identities = 23/147 (15%), Positives = 64/147 (43%), Gaps = 12/147 (8%) Query: 89 VTAYNTVTVRSRVSGELVDVPFQEGQRVKAGDLLAQVDP-------RAFQVALDQARGTQ 141 + + ++ + + ++ +EG+ V+ GD+L ++ Q +L QAR Q Sbjct: 91 THSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQ 150 Query: 142 MQNLALLENARRDLQRYQALFKQ---DSIAKQQVDTQAALVRQYEGTIKSD--QANVDNA 196 + L + + L + ++++++V +L+++ T ++ Q ++ Sbjct: 151 TRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLD 210 Query: 197 RLQLDYARITAPISGRLGLRQVDRGNL 223 + + + + A I+ L +V++ L Sbjct: 211 KKRAERLTVLARINRYENLSRVEKSRL 237
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 240 bits (613), Expect = 8e-81 Identities = 126/274 (45%), Positives = 164/274 (59%), Gaps = 3/274 (1%) Query: 15 FVALAALAGLFAGGWLTRLTHRLPRMMEHEWQAQCQEAAGKPRSA---AAYGLLAPAAHC 71 + +L L L G +L + HRLP M+E EWQA+ + Y L+ P + C Sbjct: 15 YFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDEPPYNLMVPRSCC 74 Query: 72 PACQAPVTGWRRLPLLGWLALRGRCAACHAPIGWRYPAIESMTCILFAACAWRFGATPIA 131 P C P+T +PLL WL LRGRC C API RYP +E +T +L A A Sbjct: 75 PHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSVAVAMTLAPGWGT 134 Query: 132 LCAMGLSAALVALAWIDLETTLLPDAITLPLAWAGLLVNLFDAFTPLSMAVVGAVAGYVF 191 L A+ L+ LVAL +IDL+ LLPD +TLPL W GLL NL F L AV+GA+AGY+ Sbjct: 135 LAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDAVIGAMAGYLV 194 Query: 192 LWVIFHAFRLLTGREGMGFGDFKLLAALGAWFGVGALPMLLLAASVAGVVVGGALTLSGR 251 LW ++ AF+LLTG+EGMG+GDFKLLAALGAW G ALP++LL +S+ G +G L L Sbjct: 195 LWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAFMGIGLILLRN 254 Query: 252 ASRGQALPFGPYLALAGVAVLLLGGEQGLGWLLH 285 + + +PFGPYLA+AG LL G +L + Sbjct: 255 HHQSKPIPFGPYLAIAGWIALLWGDSITRWYLTN 288
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 80.6 bits (199), Expect = 2e-19 Identities = 71/349 (20%), Positives = 126/349 (36%), Gaps = 61/349 (17%) Query: 1 MRIAVTGSTGYIAQALIKHLANQENEVLAI---------SRGQPITALATLPGVQW---- 47 M+ VTG+ G+I + K L ++V+ I S Q L PG Q+ Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 48 LSTADGIPSAAALRGCHAVVHLAGRAHTRVAHEGGRDLFDESNRVLALNCSDASREAGVD 107 L+ +G+ A V R R + E D SN LN + R + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYAD-SNLTGFLNILEGCRHNKIQ 119 Query: 108 RFVFISTLGVHGGSSPKPVTENSPMTG-VSPYARSKIEAE---QQLAENYRNTPETLCIV 163 ++ S+ V+G + P + + + VS YA +K E + Y P T + Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLY-GLPAT--GL 176 Query: 164 RPPMVYGPSCPGN--FPRLINLVRRGLPLP-FASIHSRRSFIHVDNLA------------ 208 R VYGP + + + G + + +R F ++D++A Sbjct: 177 RFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPH 236 Query: 209 ------HFLGAVSSCQVPGGTYVIGDESDFTVPELIRMIGQAFGLPTR--LIPFPPSLLL 260 G ++ P Y IG+ S + + I+ + A G+ + ++P P Sbjct: 237 ADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQP---- 292 Query: 261 AAAHLVGRRGEMESLTQAMEVDWSRARDFAGWTPPIPGRQALQDTLENY 309 G++ T A D + G+TP + +++ + Y Sbjct: 293 ---------GDVLE-TSA---DTKALYEVIGFTPETTVKDGVKNFVNWY 328
>PF03309#Bvg accessory factor Length = 271 Score = 95.6 bits (238), Expect = 2e-25 Identities = 57/287 (19%), Positives = 90/287 (31%), Gaps = 58/287 (20%) Query: 1 MIILIDSGNSRLKVGWLDPGSPD--------MPREPAAVAFDGLDLDALDRWLGALPRRP 52 M++ ID N+ VG + + EP A D L + L Sbjct: 1 MLLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTA------DELALTIDGL---- 50 Query: 53 SRALGVNVAGAERGAAIAAV-----------LQRH-GCPVTWATSQATTLGLVNRYKTPS 100 +G + A GA+ + L+++ G+ P Sbjct: 51 ---IGDD-AERLTGASGLSTVPSVLHEVRVMLEQYWPNVPHVLIEPGVRTGIPLLVDNPK 106 Query: 101 QLGADRWASLLGVLSHLPGAHPPFLLASFGTATTIDTVGPDNVFAGGLILPGPAMMRNAL 160 ++GADR + L A ++ FG++ +D V F GG I PG + +A Sbjct: 107 EVGADRIVNCLAAYHKYGTAA---IVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAA 163 Query: 161 AHGTANLP---IADGQVVPYPTDTHEAIASGIAAAQAGAV----VRQWLTGRQRYGQAPQ 213 A +A L + + V +T E + +G AG V R G Sbjct: 164 AARSAALRRVELTRPRSV-IGKNTVECMQAGAVFGFAGLVDGLVNRIRDDVDGFSGADVA 222 Query: 214 IFAAGGGWPEVHQEIERLLADAGGAFGAAPVPVYLDHPVLDGLAAIA 260 + A G L+ Y H LDGL + Sbjct: 223 VVATGHT--------APLVLPDLRTV-----EHYDRHLTLDGLRLVF 256
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 29.8 bits (67), Expect = 0.012 Identities = 22/123 (17%), Positives = 45/123 (36%), Gaps = 6/123 (4%) Query: 132 RIEQRGGRL---ISNVEDATEQLRRLLSEQNVQALTASLQNATDITHSLKEASRDLGPAL 188 ++ R+ V ++ L +QNV L + L N+ +I+ S +A + Sbjct: 72 KLSDSQARVSDVEEQVNQYLSKVPELEQKQNVSELLSLLSNSPNISLSQLKAYLE---GK 128 Query: 189 AKLGPLVDSLGSTSRQADRAAREVADLAQQARQSLARLNAPDGALAAATRSLNDIAFAAS 248 ++ + R A + E+A L+ Q+L + G + A+ S Sbjct: 129 SEEPSEQFKMLCGLRDALKGRPELAHLSHLVEQALVSMAEEQGETIVLGARITPEAYRES 188 Query: 249 RLD 251 + Sbjct: 189 QSG 191
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 28.3 bits (63), Expect = 0.023 Identities = 24/129 (18%), Positives = 46/129 (35%), Gaps = 27/129 (20%) Query: 107 PWVLAGFSFGTAVAAQTYAAL-ADQGDTVLPSALMLMGPAVNRFQSH------------- 152 +L G+SFG V + A VL + L+ + + F+ H Sbjct: 118 KVILIGYSFGAEVIPFVLNEMPARYRKNVLGAVLLSPSQSSD-FEIHVSEMVTSDNQSAR 176 Query: 153 -------EVQVPGDTLMVHG-EEDEVVPLSEAMDWARPRSIPVVVIPGASHFFHGKLLVL 204 Q L ++G E+D + L + + ++ V+ + G F + Sbjct: 177 YLTLPEVNKQTTVPMLCLYGKEDDAPLHLCPEV---KQPNVTVMELSGGHS-FDDDYDKV 232 Query: 205 RQLVQAHLK 213 +L++ LK Sbjct: 233 VKLIKGWLK 241
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 28.7 bits (64), Expect = 0.020 Identities = 7/19 (36%), Positives = 11/19 (57%) Query: 99 LRCAYAFALDQGYEGIVTI 117 ++ D+GY+GI TI Sbjct: 124 FLSMINYSKDKGYDGIYTI 142
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 113 bits (283), Expect = 2e-32 Identities = 70/250 (28%), Positives = 115/250 (46%), Gaps = 17/250 (6%) Query: 10 ALVTGGASGMGLAIVERLARDGFRVVMADRNAALADKETQALRAQGLDVDYRAVDLADEH 69 A +TG A G+G A+ LA G + D N +K +L+A+ + D+ D Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 70 ATRALV----RELAPLAALVNNAGLFDERKFFDVTSDDYRRMYDVNLLAVATLTQEAARD 125 A + RE+ P+ LVN AG+ ++ +++ + VN V ++ ++ Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKY 130 Query: 126 MAA--GGKIVNIASRAYLGAR-NHPHYVASKAALVGYTRASAMELAPRGILVNAIAPGLI 182 M G IV + S R + Y +SKAA V +T+ +ELA I N ++PG Sbjct: 131 MMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGST 190 Query: 183 DTPLLRNLSPERLAAQLALQ----------PTGRAGQPRDVANAVSFLASPQMDFITGQV 232 +T + +L + A+ ++ P + +P D+A+AV FL S Q IT Sbjct: 191 ETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMHN 250 Query: 233 IFVDGGKSLG 242 + VDGG +LG Sbjct: 251 LCVDGGATLG 260
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 121 bits (304), Expect = 2e-35 Identities = 75/252 (29%), Positives = 116/252 (46%), Gaps = 10/252 (3%) Query: 5 MQDKRVLVTGAGRGLGATIAQGFAREGASVIVADLDPALARASAQAIAAAGGRAIDAALD 64 ++ K +TGA +G+G +A+ A +GA + D +P ++ A A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 65 VTDAEAVRAFAAECEARHGAIDVLVNNAGISARAPFDDPQTPQIWERVMNVNLQGTFNVT 124 V D+ A+ A E G ID+LVN AG+ + WE +VN G FN + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEE-WEATFSVNSTGVFNAS 124 Query: 125 HAFVEQLKARR-GAIVNLCSIVAYGCGISTAGYVVSKGGVRSFTEVLARDLAPHGVRVNA 183 + + + RR G+IV + S A S A Y SK FT+ L +LA + +R N Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 184 VAPGLMETEMTAGQRAQAHGTDWYMRRA--------PMARAGRADEIVGPVLFLASDMAS 235 V+PG ET+M A +G + ++ + P+ + + +I VLFL S A Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244 Query: 236 YVNGVVLPVDGG 247 ++ L VDGG Sbjct: 245 HITMHNLCVDGG 256
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 28.6 bits (63), Expect = 0.029 Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 11/105 (10%) Query: 107 LRQDRQAVKADLDMV-------CDTFPRLRERFEQKAATLSGGEQQMLATGRAMMARPRM 159 L+Q +++ KA L ++ D + +RF+ + G +Q A R MMA Sbjct: 611 LQQQQESAKAQLSILINRSGSWADVARQSLQRFDSTRPVVKFGTEQYTAIHRQMMAAHAA 670 Query: 160 ILLDEPSM---GLSPLVVEQIFDIVLRLNREQGITILLVEQNVKL 201 I L E S + V+ I ++++L R + LVEQ KL Sbjct: 671 ITLQEVSEFTDDMRNFTVDSI-PLLIQLGRSSLMDEHLVEQREKL 714
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 105 bits (264), Expect = 1e-29 Identities = 82/266 (30%), Positives = 126/266 (47%), Gaps = 26/266 (9%) Query: 8 AAGPAPRLALVTGGGGGIGATICQELARAGYRVVVSDVDAQRARRVADELGAP---HSAH 64 A G ++A +TG GIG + + LA G + D + ++ +V L A A Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF 62 Query: 65 AFDVSDESAVETAFDQIEQAHGPIAVLVSAAGLLLFQPNGERPLIKDTTLDIWERSFAVN 124 DV D +A++ +IE+ GPI +LV+ AG+L + WE +F+VN Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSD------EEWEATFSVN 116 Query: 125 ARGVFLCGRA---YLRRREAAPLKHGRIVTFTSVAAQLGGYRSSASYIAAKSAVLGLTKA 181 + GVF R+ Y+ R + G IVT S A + S A+Y ++K+A + TK Sbjct: 117 STGVFNASRSVSKYMMDR-----RSGSIVTVGSNPAGVP-RTSMAAYASSKAAAVMFTKC 170 Query: 182 MARESAHLGVTVNGIAPGLIDTDMLRSTVTS--------SGALAAAAQAIPLGRIGTVDD 233 + E A + N ++PG +TDM S G+L IPL ++ D Sbjct: 171 LGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSD 230 Query: 234 VAAAVRFLASEEAGYITGSVIDVNGG 259 +A AV FL S +AG+IT + V+GG Sbjct: 231 IADAVLFLVSGQAGHITMHNLCVDGG 256
>cloacin#Cloacin signature. Length = 551 Score = 29.7 bits (66), Expect = 0.014 Identities = 18/55 (32%), Positives = 21/55 (38%), Gaps = 2/55 (3%) Query: 60 GHGRGARYATGDWHEGGRGRHGRHAGGGGGGWFG--GPWGGRGGDADDSFGGDGR 112 GH GA +G+ + G G G GW PWGG G GG G Sbjct: 8 GHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 28.7 bits (64), Expect = 0.026 Identities = 5/31 (16%), Positives = 16/31 (51%), Gaps = 1/31 (3%) Query: 234 AKAVREIMVAQHGVDKSRIRAASYWKRGAIA 264 A++V + ++++ G+ +I A + + Sbjct: 278 AQSVVDYLISK-GIPADKISARGMGESNPVT 307
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 30.5 bits (68), Expect = 0.041 Identities = 31/99 (31%), Positives = 39/99 (39%), Gaps = 7/99 (7%) Query: 365 ARDAAGPTSEADAATEADAATQADAATAATAAAEADAAIETAAADTVTAPANIDVAQDPA 424 AA + EA AA +A A+A A A AAI AA+T PAN V A Sbjct: 206 TLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIR--AANTYAMPANGSVVATAA 263 Query: 425 -----QVEADAQAVADAAAAGAEAAAAAADAATSADAGG 458 QV A ++A A + +A S A G Sbjct: 264 GRGLIQVAQGAASLAQAISDAIAVLGRVLASAPSVMAVG 302
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 64.3 bits (156), Expect = 5e-15 Identities = 29/140 (20%), Positives = 48/140 (34%), Gaps = 8/140 (5%) Query: 5 QILDAALQEFSAAGYTGARMDDIALRAGLSKGGLYAHFASKEEVFEALLARYLCPPRLDA 64 ILD AL+ FS G + + +IA AG+++G +Y HF K ++F + + Sbjct: 15 HILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE--SNIGE 72 Query: 65 RALVEGSATPRHLAERLVNHLYASLANPAMISAMRLLLAESLRVPHLA------RRWREQ 118 L + P L L L + RLL+ ++ + Sbjct: 73 LELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRN 132 Query: 119 TADAHQADIAQLLELARARG 138 I Q L+ Sbjct: 133 LCLESYDRIEQTLKHCIEAK 152
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 44.5 bits (105), Expect = 7e-09 Identities = 22/63 (34%), Positives = 38/63 (60%), Gaps = 3/63 (4%) Query: 7 RRRGRQRGFTLIEVLVALAIIAVAMGAALRATGVMAANNRALQDKTLA-LLAAQNALTQL 65 R +QRGFTL+E++V + II V A+L +M +A + K ++ ++A +NAL Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVL--ASLVVPNLMGNKEKADKQKAVSDIVALENALDMY 59 Query: 66 RLE 68 +L+ Sbjct: 60 KLD 62
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 31.1 bits (70), Expect = 8e-04 Identities = 13/72 (18%), Positives = 23/72 (31%), Gaps = 1/72 (1%) Query: 1 MVVLVIVAIAASMVSLSVGKGA-DPLRDDAQRLLDAFTVAEGEARSDGRALRWSPASGGW 59 M++L+++ ++A MV L+ D R + G+ S W Sbjct: 12 MLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQFFGVSVHPDRW 71 Query: 60 SFERAGRSDAPT 71 F D Sbjct: 72 QFLVLEARDGAD 83
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 171 bits (436), Expect = 3e-58 Identities = 64/142 (45%), Positives = 90/142 (63%), Gaps = 8/142 (5%) Query: 6 RGLARQQGFTLIEIMVVIVIMGILAALIVPRVLDRPDQARQVAARQDIGGIMQALKLYRL 65 R +Q+GFTL+EIMVVIVI+G+LA+L+VP ++ ++A + A DI + AL +Y+L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKL 61 Query: 66 DNGRYPTTAQGLRALVEKPEGA---SNWR--GYLDKLPNDPWGHPYQYLSPGVKGEIDVF 120 DN YPTT QGL +LVE P +N+ GY+ +LP DPWG+ Y ++PG G D+ Sbjct: 62 DNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLL 121 Query: 121 SFGADNKPGGEGGDADIGSWEL 142 S G D + G E DI +W L Sbjct: 122 SAGPDGEMGTED---DITNWGL 140
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 70.8 bits (173), Expect = 2e-17 Identities = 43/184 (23%), Positives = 65/184 (35%), Gaps = 18/184 (9%) Query: 3 TPAAPSDVRQHILDVARPLLLARGYTAVGLAEVLAAAKVPKGSFYHYFASKDAFGVALLE 62 T + RQHILDVA L +G ++ L E+ AA V +G+ Y +F K + E Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 63 DYFKGYLAYMDGLMAGPGNG-----RERLVRYFHEWRETQGCESAHSRCLVVKLGAEVCD 117 A RE L+ + R L++++ C+ Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLES------TVTEERRRLLMEIIFHKCE 118 Query: 118 LSDPMRTVLQAGTRA---ITERIERGIEAGRADGSLPPA--PGALAPAILAA--NLYEHW 170 M V QA +RIE+ ++ LP A + L E+W Sbjct: 119 FVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENW 178 Query: 171 LGAS 174 L A Sbjct: 179 LFAP 182
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 54.6 bits (131), Expect = 2e-11 Identities = 20/97 (20%), Positives = 40/97 (41%), Gaps = 1/97 (1%) Query: 1 MAGPAS-RKELSHDRIVEAAARAIRREGYAGVGVADVMKEAGLTHGGFYAHFPSRDAMLV 59 MA + + I++ A R ++G + + ++ K AG+T G Y HF + + Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 60 AAMERAGRDGAARMAQGMARRRAEGASPLRALVESYL 96 E + + + A+ + S LR ++ L Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVL 97
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 50.0 bits (119), Expect = 1e-09 Identities = 47/207 (22%), Positives = 85/207 (41%), Gaps = 15/207 (7%) Query: 3 LKNATVLITGANRGIGLAFAREALARGARKVYAGARDPASISLPGLQAIKLDVTSDE--- 59 ++ ITGA +GIG A AR ++GA + A +P + ++ Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGA-HIAAVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 60 DVAAAAALAKDVT----------LVINNAGIAATGGFLAGDSIESARRHLETNLLGPLRV 109 DV +AA+ + +++N AG+ G + S E N G Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPG-LIHSLSDEEWEATFSVNSTGVFNA 123 Query: 110 AQAFAPVLAANGGGALLNVLSIASWINRPLLGVYGMSKSAAWALTNGLRHELREQGTQVL 169 +++ + + G+++ V S + + R + Y SK+AA T L EL E + Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 170 GLHMGFVDTDLTRGLDAPKSTPESVVR 196 + G +TD+ L A ++ E V++ Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIK 210
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 118 bits (297), Expect = 4e-31 Identities = 93/423 (21%), Positives = 162/423 (38%), Gaps = 31/423 (7%) Query: 25 IFWIASVAVFLVSLDATMLYAAFGAMRAGFPEASAADMSWVLNAYTVVYAAMLIPSGGLA 84 + W+ + F L+ +L + + F A +WV A+ + ++ G L+ Sbjct: 16 LIWLC-ILSFFSVLNEMVLNVSLPDIANDF-NKPPASTNWVNTAFMLTFSIGTAVYGKLS 73 Query: 85 DTHGRKRMFMIGVLLFLAASAACGLAGT-VGWLIAARVAQAVGAALLTPASLSIVLAAF- 142 D G KR+ + G+++ S + + LI AR Q GAA PA + +V+A + Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAF-PALVMVVVARYI 132 Query: 143 PAAQRSVAVSLWGAVAALAAAVGPSLGAFVVDAAGWPWAFYINLPLGALSLWFGAARLVE 202 P R A L G++ A+ VGP++G + W + + +P+ + L++ Sbjct: 133 PKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITI---ITVPFLMK 187 Query: 203 SVRPEARRR--VDGVGMALLMVGVGALALAIVQSESPHWSRGELWMVAAVGLVSLVAFVG 260 ++ E R + D G+ L+ VG+ L V ++S + FV Sbjct: 188 LLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSY---------SISFLIVSVLSFLIFVK 238 Query: 261 WARSTPHPLVDLALFRHRTYRYVNLATLSFGIAFAMM--FFAFFFYMTG-VWHYSLPRAG 317 R P VD L ++ + + L GI F + F + YM V S G Sbjct: 239 HIRKVTDPFVDPGLGKNIPFM---IGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIG 295 Query: 318 LAVT-PGPLLVMPTAIITGKLAARMGHRPFLVGGALVYAASGLWFLLVPGAEPAYLAHWL 376 + PG + V+ I G L R G L G + S L + ++ + Sbjct: 296 SVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMT-II 354 Query: 377 PGLLLSGLGVGMVLPSLAGAAVNRLPPQHYAVGSAVNQATRQIGAVLGVALTVLLLGKGA 436 +L GL ++ + L Q G ++ T + G+A+ LL Sbjct: 355 IVFVLGGLSFTKT--VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPL 412 Query: 437 LSH 439 L Sbjct: 413 LDQ 415
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 53.9 bits (129), Expect = 5e-09 Identities = 58/231 (25%), Positives = 88/231 (38%), Gaps = 28/231 (12%) Query: 1234 DDAWRLGVMAGYGSQRSKARGSMSGYQSRGDITGYSAGVYGTWYQDARTRAGLYVDGWAL 1293 W LG +AGY ++ +G G G Y T+ D+ G Y+D Sbjct: 687 GGRWHLGGLAGY----TRGDRGFTGDGG-GHTDSVHVGGYATYIADS----GFYLDATLR 737 Query: 1294 FNRFDNTVKGDGLD----KEQYTSQGVTASVEAGYLFEAGSHTTGSGRENRFYVRPQAQV 1349 +R +N K G D K +Y + GV AS+EAG F + +++ PQA++ Sbjct: 738 ASRLENDFKVAGSDGYAVKGKYRTHGVGASLEAGRRFT---------HADGWFLEPQAEL 788 Query: 1350 LWSGVTAGDYTERSGTKVQGGSSGNVRTRLGARLSLASTRPSAGPGRTGQVEVFLDANWL 1409 G Y +G +V+ +V RLG R GR QV+ ++ A+ L Sbjct: 789 AVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLE---VGKRIELAGGR--QVQPYIKASVL 843 Query: 1410 HAAHPYG-VTMDDTRSVVQGGRNVVELRAGVEGRLTDRLSLSADMTQRQGS 1459 G V + + EL G+ L SL A +G Sbjct: 844 QEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALGRGHSLYASYEYSKGP 894 Score = 31.6 bits (71), Expect = 0.032 Identities = 29/101 (28%), Positives = 31/101 (30%), Gaps = 8/101 (7%) Query: 1056 PDDPVSPGAGTAGGGDAAGGGTAGGGDAAGGGTAGGGDAAGGDAAGGGTAGGGDA----- 1110 P V A+G A A T GG GG AAG G Sbjct: 197 PPSRVVLRDTNVTAVPASGAPAAVSVLGASELTLDGGHITGGRAAGVAAMQGAVVHLQRA 256 Query: 1111 ---AGGGTAGGGTAGGGTAGGGTAGGGDAAGGGTAGGGTHG 1148 G AGG GG GG GG G G G +G Sbjct: 257 TIRRGDAPAGGAVPGGAVPGGAVPGGFGPGGFGPVLDGWYG 297
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 59.1 bits (142), Expect = 1e-11 Identities = 79/313 (25%), Positives = 121/313 (38%), Gaps = 6/313 (1%) Query: 147 AAVVQAALTANDAIATPRTPVPATAQQAEAAAALASRDAQVAQPVVTAAVKAGSAPAVEA 206 + +V A AN I TP +Q+ + ++ +A K A + Sbjct: 66 SDIVSDAQQANLLIPVDETPPVINDEQSTSTPLTTAQTMALAAVADKNTTKDEKADDLNE 125 Query: 207 APVKTAPAAELPRPAPEAAAPRAANPRVAAPEAAPALPQHARTEE-DPAAPLPSTAQQFQ 265 + A P + P P P L +E+ A P + Q Sbjct: 126 DVTASLSALFAMLPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAPGTPAQ 185 Query: 266 LPQHATNAQDHLAQAIAAASQRQQPA-PVSNPASVAVPNVPVMLQVATPVGGTHWGTELG 324 A+ I+ S A P+ P ++ P+G W L Sbjct: 186 PLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEWQQSLS 245 Query: 325 QQMVVMSNNVRQGTQTAELRLDPPDLGPLRVSINLADGVASASFVSAHASVRQAIETAIP 384 Q + + + RQG Q+AELRL P DLG +++S+ + D A VS H VR A+E A+P Sbjct: 246 QHISLFT---RQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAALP 302 Query: 385 QLQQALAQAGISLGQTSV-GEQAAQQEFAQHNGGGSQRQGGGNGAAVADAAIDGQAATVT 443 L+ LA++GI LGQ+++ GE + Q+ A SQR A D ++ Sbjct: 303 VLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVSLQ 362 Query: 444 AARNANALVDTFA 456 N+ VD FA Sbjct: 363 GRVTGNSGVDIFA 375
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 67.5 bits (164), Expect = 3e-17 Identities = 48/145 (33%), Positives = 82/145 (56%) Query: 1 MPSQLPLDMLINLAKESTDEAARLLGRLSTERTNAERQLGMLQDYRQDYLERLQQAMTTG 60 M L L +LA++ ++AARLLG + AE QL ML DY+ +Y L M+ G Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 MSASDCHNYQRFIGTLDDAIGQQQNVLRQADENLAKGRLYWQQEKRKLNSYDALAQRELR 120 ++++ NYQ+FI TL+ AI Q + L Q + + W+++K++L ++ L +R+ Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 121 AQAVVESRREQRANDEYSARLVQRQ 145 A + E+R +Q+ DE++ R R+ Sbjct: 121 AALLAENRLDQKKMDEFAQRAAMRK 145
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 89.1 bits (220), Expect = 1e-23 Identities = 63/217 (29%), Positives = 108/217 (49%), Gaps = 8/217 (3%) Query: 21 WQMLSFDE--PPPVEVEP--EPEPDPGPDPEVVMAQLRAQAIAEGREEGYAQGHAAGLEA 76 W+ + D+ PP E P EPE + E + Q AQ + E+GY G A G + Sbjct: 7 WKTWTPDDLAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGIAEGRQQ 66 Query: 77 GRAEGHEAGLAAGREAGYAEGLAQAREQGAQEAQHLHALVQACAESVGSLEEKMGQSLLT 136 G +G++ GLA G E +GLA+A+ Q A + LV ++ +L+ + L+ Sbjct: 67 GHKQGYQEGLAQGLE----QGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQ 122 Query: 137 LALDIAQQVVRTTLAEQPETVASAVREVLHINPTAGGQMRLWANPADIELIRLHLADELK 196 +AL+ A+QV+ T + ++++L P G+ +L +P D++ + L L Sbjct: 123 MALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGATLS 182 Query: 197 EGHWRVLADESIARGGCRAETPFGDIDATLQTRWRRV 233 WR+ D ++ GGC+ GD+DA++ TRW+ + Sbjct: 183 LHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQEL 219
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 301 bits (772), Expect = e-103 Identities = 113/333 (33%), Positives = 188/333 (56%), Gaps = 2/333 (0%) Query: 2 KNDSKPMDGMTRSAVLMMSLGEDAAAEVFKYLTAREVQQVGAAMASLKQVTRNDVAVVLE 61 D + G ++A+L++S+G + +++VFKYL+ E++ + +A L+ +T VL Sbjct: 9 ILDVSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLL 68 Query: 62 EFRQEADQFMAVTLGSDDYIRTVLTKALGSDRAAGLIEDILEAGEGGSGIDALNWLDPHT 121 EF++ + G DY R +L K+LG+ +A +I + L + + + DP Sbjct: 69 EFKELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINN-LGSALQSRPFEFVRRADPAN 127 Query: 122 VAELIGDEHPQIIATILVHLERDRAAGVLALLTDRLRNDVMLRIATFGGVQPAALSELTE 181 + I EHPQ IA IL +L+ +A+ +L+ L ++ +V RIA P + E+ Sbjct: 128 ILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVER 187 Query: 182 VLNSVLAGQGA-KRSKMGGVRTAAEILNMMNSAEEETVVASLRERDNDLAQKIIDEMFVF 240 VL LA + + GGV EI+NM + E+ ++ SL E D +LA++I +MFVF Sbjct: 188 VLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVF 247 Query: 241 DNLLDIEDRAIQLILKEIDNDTLMVALKGAQEELRAKFLRNMSSRAAEMLREDLEAQGPI 300 ++++ ++DR+IQ +L+EID L ALK ++ K +NMS RAA ML+ED+E GP Sbjct: 248 EDIVLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPT 307 Query: 301 RMSKVETEQKKILQIARRLAESGQIVLGNSGDD 333 R VE Q+KI+ + R+L E G+IV+ G++ Sbjct: 308 RRKDVEESQQKIVSLIRKLEEQGEIVISRGGEE 340
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 459 bits (1183), Expect = e-159 Identities = 245/555 (44%), Positives = 345/555 (62%), Gaps = 25/555 (4%) Query: 2 LEKIRALPKPVLLGAAAALVALIVAVAMWSSEPKYKVLFSNLDDRDGGAIVTALGTMNVP 61 L ++RA P+ L+ A +A VA++VA+ +W+ P Y+ LFSNL D+DGGAIV L MN+P Sbjct: 16 LNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIP 75 Query: 62 YKYNDTGTALLVPADRVYDARLQLASQGLPRGGSVGFELMDNARFGASQFAEQINYQRGL 121 Y++ + A+ VPAD+V++ RL+LA QGLP+GG+VGFEL+D +FG SQF+EQ+NYQR L Sbjct: 76 YRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQFSEQVNYQRAL 135 Query: 122 EGELARSIESMHTVQHARVHLAMPRQSLFVRERQPPTASVLLNVYPGRSLSDAQVSAISW 181 EGELAR+IE++ V+ ARVHLAMP+ SLFVRE++ P+ASV + + PGR+L + Q+SA+ Sbjct: 136 EGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQISAVVH 195 Query: 182 LVASSVPELTAENVSIVDQNGRLLSAPTGEGRGMDADQMRMVRETEQRTVERILTILNPL 241 LV+S+V L NV++VDQ+G LL+ GR ++ Q++ + E R RI IL+P+ Sbjct: 196 LVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLNDAQLKFANDVESRIQRRIEAILSPI 255 Query: 242 VGPGNVHAQASAEMDFSRREETSEVYRPNQEPGQAAIRSQQTSESNQRGINPAQGVPGAL 301 VG GNVHAQ +A++DF+ +E+T E Y PN + +A +RS+Q + S Q G GVPGAL Sbjct: 256 VGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPGGVPGAL 315 Query: 302 SNQPPANAQAPIANPPQTQPPRPGQPQQQGQQQQQQTTTGAGAQGAGGTVSDRRDATTNY 361 SNQP +APIA PP QQ Q QT+T + AG S +R+ T+NY Sbjct: 316 SNQPAPPNEAPIATPPT---------NQQNAQNTPQTSTSTNSNSAGPR-STQRNETSNY 365 Query: 362 EVDRTISHIKQPVGMLKRLSVAVVVNYVRDKDGEPQALPPEELSKLTNLVREAMGYSESR 421 EVDRTI H K VG ++RLSVAVVVNY DG+P L +++ ++ +L REAMG+S+ R Sbjct: 366 EVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKPLPLTADQMKQIEDLTREAMGFSDKR 425 Query: 422 GDSLNLVNSQFNDGPPAV---PMWRDPEMISLFKTILAWLVGGVLALWLYRKVRRSVGDY 478 GD+LN+VNS F+ P W+ I WL+ V+A L+RK R Sbjct: 426 GDTLNVVNSPFSAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVRPQLTR 485 Query: 479 LYPPVDP-----------EVAEAERIEAQREAQDLARAKETDRYQDNLERARTMANKDPR 527 E A R+ + Q RA + + +R R M++ DPR Sbjct: 486 RVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQR-RANQRLGAEVMSQRIREMSDNDPR 544 Query: 528 AVAMVLRTWMTKDEK 542 VA+V+R WM+ D + Sbjct: 545 VVALVIRQWMSNDHE 559
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 60.1 bits (145), Expect = 2e-15 Identities = 45/107 (42%), Positives = 64/107 (59%), Gaps = 4/107 (3%) Query: 4 SGLSGIESMLQQMRVAVTKAETGNLAAGEAVAQPDGFAAELQRSIRRVTSAQNAATAQAK 63 S + GIE ++ Q++ A ++ FA +L ++ R++ Q AA QA+ Sbjct: 1 SAIQGIEGVISQLQATAMSARAQESLPQPTIS----FAGQLHAALDRISDTQTAARTQAE 56 Query: 64 AFELGAPDVSLNDVMIDLQKASIGFQTAVQVRNKLVAAYKEISSMAV 110 F LG P V+LNDVM D+QKAS+ Q +QVRNKLVAAY+E+ SM V Sbjct: 57 KFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 69.4 bits (170), Expect = 2e-17 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 2/78 (2%) Query: 18 AVAISYD-DKDAAPRVVAKGYGQLADTIVRAAEENGLYVHESRELV-GLLMQVDLDAHIP 75 A+ I Y + P V K T+ + AEE G+ + + L L +D +IP Sbjct: 268 AIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEEEGVPILQRIPLARALYWDALVDHYIP 327 Query: 76 PQLYVAVAELLAWLYRLE 93 + A AE+L WL R Sbjct: 328 AEQIEATAEVLRWLERQN 345
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 30.5 bits (68), Expect = 0.005 Identities = 20/70 (28%), Positives = 25/70 (35%) Query: 129 QPASQPGAPGQPTAAPAAGQAAAPAPAPPPRRHWPRLPRPVPTPPPRHRPPTGPRAQPDR 188 +P PG+ P A P + A PA P + RP P P P P P Sbjct: 312 RPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQP 371 Query: 189 AKAPPAPGTP 198 P +P P Sbjct: 372 GTRPDSPAVP 381
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 51.4 bits (123), Expect = 3e-09 Identities = 71/371 (19%), Positives = 115/371 (30%), Gaps = 62/371 (16%) Query: 56 MPLFTQAFGVSPAESSLVLSLCTGLLAIAIFLVGLFSQALPRKRIMALSLLASAILGTAA 115 +P F PA ++ V + +I + G S L KR++ ++ + Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 116 AIAPDWHSLLAL-RALQGVAMGGVPAVAMAYLAEEVEPDTLGFAMGLYISGSAFGGLSGR 174 + + SLL + R +QG PA+ M +A + + G A GL S A G G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 175 VITGLVSDHFGWRAAL------------------------GTLGLLGVV---AAVLFIWL 207 I G+++ + W L G + G++ ++F L Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFML 216 Query: 208 LPASRRFT------------PRRPRGWAGVAGDVRAGIGAHLRNGPLCGLFAMGGLLMGA 255 S + + R D G +N P GG++ G Sbjct: 217 FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLG-----KNIPFMIGVLCGGIIFGT 271 Query: 256 FVTVYNYVGFRLLAP-----PFSLSQTFIG--FIFVVYLVGIFASTYFGRLADRHGRGAM 308 GF + P LS IG IF + I G L DR G + Sbjct: 272 VA------GFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYV 325 Query: 309 LAAATGLALAGLLLT--LSDALPLLIAGIVVFTFGFFAAHAVASGWVGQMS--RGYKALA 364 L L L + + I+VF G + + S + Sbjct: 326 LNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAG 385 Query: 365 ASLYLLVYYVG 375 SL ++ Sbjct: 386 MSLLNFTSFLS 396
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 74.9 bits (184), Expect = 6e-16 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 1/116 (0%) Query: 875 VMVVEDEANVREMVCECLAELGMRVLAAEDGDTGLERLRANADIDLLISDVGLPGLNGRQ 934 ++V +D+A +R ++ + L+ G V + T + A D DL+++DV +P N Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA-GDGDLVVTDVVMPDENAFD 64 Query: 935 LADAARATHPGLKVLLMTGYAESAARGSGFLDTGMELIVKPFALDALAQRVQRMLE 990 L + P L VL+M+ + + KPF L L + R L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 33.1 bits (75), Expect = 2e-04 Identities = 15/70 (21%), Positives = 23/70 (32%), Gaps = 5/70 (7%) Query: 40 AVQPNRPVPPGQAAPAPNATPSTQSMPPNVDKRGTTPSSDKRSGEMPNRNSEANDNVPRT 99 A Q + + TP + V +G P + + PN+N R Sbjct: 449 AKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTK----PNQNKAPMKETKRQ 504 Query: 100 -PAAGATPPP 108 P+ G T P Sbjct: 505 LPSTGETANP 514
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 328 bits (843), Expect = e-112 Identities = 126/344 (36%), Positives = 178/344 (51%), Gaps = 32/344 (9%) Query: 2 DGIMNVSGLSPVMQKLATQVRLAAETDASVFIVGESGAGKEVVARAIHEASERRDHPFIA 61 M + G S MQ++ + +TD ++ I GESG GKE+VARA+H+ +RR+ PF+A Sbjct: 134 QDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVA 193 Query: 62 VNCGAISGSLAHAELFGHEKGSFTGAVAQNAGYFESASGGTLFLDEVTEMPPDMQVHFLR 121 +N AI L +ELFGHEKG+FTGA ++ G FE A GGTLFLDE+ +MP D Q LR Sbjct: 194 INMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLR 253 Query: 122 VLETGTYQRVGGTDLLRANARILCASNRDPAASVADGRLRQDFLHRLLVIPLRVPPLRER 181 VL+ G Y VGG +R++ RI+ A+N+D S+ G R+D +RL V+PLR+PPLR+R Sbjct: 254 VLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDR 313 Query: 182 DGDAVTLARHFLNELNARHGTSKTFSPRMLQAIGRHEWPGNVRELRNAVQRAYILCDEEL 241 D L RHF+ + K F L+ + H WPGNVREL N V+R L +++ Sbjct: 314 AEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDV 373 Query: 242 ----------DAELPRARAAPH---------------------AEFKDGA-LSFPVGTAL 269 +E+P + A F D S L Sbjct: 374 ITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVL 433 Query: 270 GNAQRDFILATLAHHGGDKRLTAETLGVSLKTLYNRLDVYEKDV 313 + ILA L G++ A+ LG++ TL ++ V Sbjct: 434 AEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSV 477
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 491 bits (1266), Expect = e-174 Identities = 175/471 (37%), Positives = 255/471 (54%), Gaps = 34/471 (7%) Query: 2 PHLLIVDDDDAIRETLAELGRDSGFTVALAASVKDALIQLERQAPDLVLTDVRLPGGSGM 61 +L+ DDD AIR L + +G+ V + ++ + DLV+TDV +P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 DIFKNVAVA--SAEVVVMTGHGTVDNAVQALRLGATDYLVKPICMERLNGILARIMSNTG 119 D+ + A V+VM+ T A++A GA DYL KP + L GI+ R ++ Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 120 RELPGTPFEAPGRFGKMYGSSAPMRELYRQIGRVAPTGVTVLLVGESGTGKELAAHAIHE 179 R + + G SA M+E+YR + R+ T +T+++ GESGTGKEL A A+H+ Sbjct: 124 RRPSKLE-DDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHD 182 Query: 180 LSTRRQRPFIAVNCGAISPHLIESEMFGHERGSFTGADRQHKGYFERADGGTLFLDEVTE 239 RR PF+A+N AI LIESE+FGHE+G+FTGA + G FE+A+GGTLFLDE+ + Sbjct: 183 YGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGD 242 Query: 240 MPLDLQVKLLRVLETGQFMRVGTNREIGCDIRIVAATNRNPEQAVQEGKLREDLYYRLNV 299 MP+D Q +LLRVL+ G++ VG I D+RIVAATN++ +Q++ +G REDLYYRLNV Sbjct: 243 MPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNV 302 Query: 300 FPLELPPLRERGEDILLLADRFLQAQNEETGRSKAFSARAAAALSQYEWPGNVRELKNFV 359 PL LPPLR+R EDI L F+Q +E K F A + + WPGNVREL+N V Sbjct: 303 VPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLV 362 Query: 360 RRAFIMAEGDELDADLLAPQVS--------PSGDVSGGQVSVPV---------------- 395 RR + D + +++ ++ G +S+ Sbjct: 363 RRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDA 422 Query: 396 -------GETLAEADRRLILATLERCKGVKKQAAAVLGISPKTLYNRLEEY 439 LAE + LILA L +G + +AA +LG++ TL ++ E Sbjct: 423 LPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL 473
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 26.1 bits (57), Expect = 0.041 Identities = 32/119 (26%), Positives = 47/119 (39%), Gaps = 17/119 (14%) Query: 8 LSLTLIPAAALGLSALALPAAAQTASGASSAVR-------------SNEQID-NQYKMDK 53 + + L+ AA +GL+ AA S + + N+ ID N + K Sbjct: 1 MKMKLVTAAIMGLAMSTAMAATDATSLTTDKDKLSYSIGADLGKNFKNQGIDINPDVLAK 60 Query: 54 KQCDAMKGNQKDVCEQQAQATRDKARADAKAGKEKAEANHDAA--KARNEADYKVGKEK 110 D M G Q + E+Q + K + D A K AE N A KA+ +A K K Sbjct: 61 GMQDGMSGAQLILTEEQMKDVLSKFQKDLMA-KRSAEFNKKAEENKAKGDAFLSANKSK 118
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 28.9 bits (64), Expect = 0.038 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 8/80 (10%) Query: 15 ALALQATLAAPAAHAAYPEQAIKLVVPFTPG----GATDAVARLLAN---RLSGKLGQAV 67 A+AL A AAPAAHA + Q+I G G+ R + ++SG+ Q + Sbjct: 20 AMALGALGAAPAAHADWNNQSIVKTGERQHGIHIQGSDPGGVRTASGTTIKVSGRQAQGI 79 Query: 68 IVENRPGASTVIGANAVAQA 87 ++EN P A +V + Sbjct: 80 LLEN-PAAELQFRNGSVTSS 98
>PERTACTIN#Pertactin signature. Length = 922 Score = 32.4 bits (73), Expect = 0.010 Identities = 54/183 (29%), Positives = 66/183 (36%), Gaps = 27/183 (14%) Query: 640 GASPLWAQAFGNWSTLGGDGNASSVKQSAGGFFVGGDGAV---GGGWRLGGALGYT-GSH 695 A W + F L + Q GF +G D AV GG W LGG GYT G Sbjct: 657 DAGGAWGRGFAQRQQLD-NRAGRRFDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDR 715 Query: 696 SSIADAASRTDVDSYTATLFGGRNFAAGPGHVRFMAGAAYTWHDIDTKRNVAAGSLNQQL 755 D TD + GG +A + F A ++ V AGS + Sbjct: 716 GFTGDGGGHTD-----SVHVGG--YATYIANSGFYLDATLRASRLENDFKV-AGSDGYAV 767 Query: 756 KSSYRASSTQVFTELGYHLPLNDAYAIEPFAGL-----------AWNQLRTRDFEESGGS 804 K YR V E G D + +EP A L A N LR RD GGS Sbjct: 768 KGKYRTHGVGVSLEAGRRFAHADGWFLEPQAELAVFRVGGGAYRAANGLRVRD---EGGS 824 Query: 805 AAL 807 + L Sbjct: 825 SVL 827
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 93.0 bits (231), Expect = 1e-26 Identities = 41/137 (29%), Positives = 67/137 (48%), Gaps = 1/137 (0%) Query: 35 ISAVLNQVLADVFALYLKTKNFHWHVSGPHFRDYHLLLDEQGDQLFAMTDPIAERIRKIG 94 + LN L++ F LY K FHW+V GPHF H +E D D IAER+ IG Sbjct: 13 VENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIAERLLAIG 72 Query: 95 GTTLRSIGHISRSQRIADNDADYVQPLDMLAELREDNKTLAATLREAHNVTDEHRDIASS 154 G + ++ + I D + +M+ L D K +++ + + +E++D A++ Sbjct: 73 GQPVATVKEYTEHASITDGGNETSAS-EMVQALVNDYKQISSESKFVIGLAEENQDNATA 131 Query: 155 SLIENWIDETERRTWFL 171 L I+E E++ W L Sbjct: 132 DLFVGLIEEVEKQVWML 148
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.8 bits (134), Expect = 8e-12 Identities = 31/144 (21%), Positives = 55/144 (38%), Gaps = 12/144 (8%) Query: 7 ESPATERAADTRDRLLRAGLALFSQLGLEGVRTRQLAQAAGVNQSAIPYHFGGKEGVYAA 66 + A +TR +L L LFSQ G+ ++A+AAGV + AI +HF K +++ Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 67 VLEQTAQAIAE--------RLDWPDTAPRTAADAALQL---EAIMRGFAAALL-DSEASA 114 + E + I E P + R L+ E R + E Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 115 ARSLLLAREQLQPTPKFEAIHAVL 138 +++ ++ ++ I L Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTL 145
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 49.2 bits (117), Expect = 2e-09 Identities = 23/144 (15%), Positives = 52/144 (36%), Gaps = 4/144 (2%) Query: 12 RPARPDAEL-RAAALEAATWLLLNQGYAAATLEAVAKRAGMAKKTVYRFAANREDLVAQV 70 R + +A+ R L+ A L QG ++ +L +AK AG+ + +Y ++ DL +++ Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 71 VRGWTDTFEPVMAQDVGSAADVLPALARVLQAIADRALSADAVGMFRLLTADFPARAALL 130 + + ++ A VL+ I L + R L + Sbjct: 63 WEL---SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 131 AVYQENGIERGTAMLAAWFEKLAA 154 + + ++++ Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQ 143
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 32.2 bits (73), Expect = 0.004 Identities = 23/130 (17%), Positives = 51/130 (39%), Gaps = 4/130 (3%) Query: 61 TPVVAHVADQRGGAHGLIFAALAASLALFICYPFSQAPAWLFGVTLLLNAVFPAVLPLLD 120 T V ++DQ G L+F + I + + L + + A P L Sbjct: 66 TAVYGKLSDQLGIKRLLLFGIIINCFGSVIGF-VGHSFFSLLIMARFIQGAGAAAFPALV 124 Query: 121 RMAIA---SGRGQGNSYTIIRACGSLGFALVTVAGGYLIKTFGADWVMWLSMLLIVACLA 177 + +A +G ++ +I + ++G + GG + +++ + M+ I+ Sbjct: 125 MVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPF 184 Query: 178 CVRLLPQAAR 187 ++LL + R Sbjct: 185 LMKLLKKEVR 194
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.006 Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 4/41 (9%) Query: 41 EPG---EFVVAL-GASGCGKTTLLSLLAGFLSPTDGEITLG 77 EPG ++ V L G G GK+TL++ L G +D +G Sbjct: 590 EPGCKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIG 630
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 378 bits (972), Expect = e-129 Identities = 161/477 (33%), Positives = 270/477 (56%), Gaps = 8/477 (1%) Query: 5 HAMGAWRDLARRYGAVFAYSWRERKSRERTRYRGDEAEFLPAALSLQEQTVSPAPRVAMW 64 + + + RY V++ +W+ RK + DE EFLPA L L E VS PR+ + Sbjct: 3 TWLMGFSEFLLRYKLVWSETWKIRKQLDTPVREKDENEFLPAHLELIETPVSRRPRLVAY 62 Query: 65 LLIVFAALALAWSVLGRVDIVATAQGKIIPSEGTQVVQPIGTATIKAIHVREGQAVRAGD 124 ++ F +A SVLG+V+IVATA GK+ S ++ ++PI + +K I V+EG++VR GD Sbjct: 63 FIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGD 122 Query: 125 LLIELDGTVTRAEQQRIVNELQTWALQAAHAEAMLIAIDQGSAPVLDHVPADSRMT---- 180 +L++L A+ + + L L+ + + +I+ P L +P + Sbjct: 123 VLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELK-LPDEPYFQNVSE 181 Query: 181 ---EDARRLARAEFLALQAKLAGIDAEIVRRQAELQTTQALTRKLERTAPIARQRAESLK 237 L + +F Q + + + +++AE T A + E + + + R + Sbjct: 182 EEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFS 241 Query: 238 ELAGDQYVARNAYLERERERIEQESDLVMQRSRLKEIEATIAEARQQRETVRADALHASL 297 L Q +A++A LE+E + +E ++L + +S+L++IE+ I A+++ + V + L Sbjct: 242 SLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEIL 301 Query: 298 NRLNEARQRMALLEQDLVKARQSEHLTRLNAPVSGTVQQLAVRTVGGVVTEAQPLMLVVP 357 ++L + + LL +L K + + + + APVS VQQL V T GGVVT A+ LM++VP Sbjct: 302 DKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVP 361 Query: 358 QEHVLEIEAFLENKDVGFVVPGQDAEVKVETFPYTKYGIVPSTVKSVSDDAINDEKRGLV 417 ++ LE+ A ++NKD+GF+ GQ+A +KVE FPYT+YG + VK+++ DAI D++ GLV Sbjct: 362 EDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLV 421 Query: 418 YSMRIEMARSTIAVNGADIRLAPGMAVTAEIKTGRRRVIEYFLDPLLQYGAESIRER 474 +++ I + + ++ +I L+ GMAVTAEIKTG R VI Y L PL + ES+RER Sbjct: 422 FNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLEESVTESLRER 478
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 133 bits (336), Expect = 4e-33 Identities = 79/255 (30%), Positives = 110/255 (43%), Gaps = 49/255 (19%) Query: 1660 KLEGSAGNDVLIGGAGDDTLYGHGGDDKLHGGDGDDTLYGGDGIDHLYGGAGRNTLVGGA 1719 K GS D+ G GDD + G+ G+D+L+G G+DTL GG+G D LYGG G + L+G A Sbjct: 730 KFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVA 789 Query: 1720 GSDVYHVDSADDVIIELPDQGTDRVFATVSYTLADNVEHLHLEGDQAIDGTGNGGNNLLL 1779 G++ + DD E QG + N+L Sbjct: 790 GNNYLNGGDGDD---EFQVQG------------------------------NSLAKNVLF 816 Query: 1780 GNGAANTLNGGGGDDTLNGGGGDDTLIGGDGNDRYVIARDSGMDRVIEDDDTAGNNDVVA 1839 G + L G G D L+GG GDD L GG GND Y G + +D G D ++ Sbjct: 817 GGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDDD---GGKEDKLS 873 Query: 1840 FGAGVAADQLWFSRLGNDL-------EVRIIGTAGGVTISNWFL-----GARYRVEQFTT 1887 A + + F R GNDL V IG G+T NWF + + +EQ Sbjct: 874 L-ADIDFRDVAFKREGNDLIMYKGEGNVLSIGHKNGITFRNWFEKESGDISNHEIEQIFD 932 Query: 1888 TQGAILREDKVEALV 1902 G I+ D ++ + Sbjct: 933 KSGRIITPDSLKKAL 947 Score = 111 bits (279), Expect = 2e-26 Identities = 76/253 (30%), Positives = 111/253 (43%), Gaps = 51/253 (20%) Query: 1946 GTAGDDILEGASNNDVLWGLDGDDILIGNDGDDHLHGGTGANTLIGGKGNDVYYIDSPLD 2005 GT D G+ D+ G DGDD++ GNDG+D L+G G +TL GG G+D Y Sbjct: 724 GTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLY------ 777 Query: 2006 RIIELAGEGGDRVESTISFTLPEHVEGLALKGSGAIN-GTGNDATNTLLGNNAANVLSAG 2064 G+G D++ + + G+ +N G G+D + A NVL G Sbjct: 778 -----GGDGNDKL--------------IGVAGNNYLNGGDGDDEFQVQGNSLAKNVLFGG 818 Query: 2065 KGND---------LINGMDGDDILIGGLGSDRYLFAQEFGQDRIIETESDPGDVDVAVLG 2115 KGND L++G +GDD+L GG G+D Y + +G I + D G D L Sbjct: 819 KGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDD---DGGKEDKLSLA 875 Query: 2116 GRSFDQLWFRRVGEDL-------EVSVIGTQNRVTVERWYA-----GEQHRIEK-FQAGA 2162 F + F+R G DL V IG +N +T W+ H IE+ F Sbjct: 876 DIDFRDVAFKREGNDLIMYKGEGNVLSIGHKNGITFRNWFEKESGDISNHEIEQIFDKSG 935 Query: 2163 RFLLDTKVENLVN 2175 R + ++ + Sbjct: 936 RIITPDSLKKALE 948 Score = 110 bits (276), Expect = 4e-26 Identities = 70/233 (30%), Positives = 106/233 (45%), Gaps = 20/233 (8%) Query: 1401 GYLHTGNLTGSSYDDVLLGDSQNNVIQGGAGNDRIAGGAGNNTLDGGAGIDTVDYSGAGA 1460 G GS + D+ G +++I+G GNDR+ G GN+TL GG G D + Y G G Sbjct: 724 GTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQL-YGGDGN 782 Query: 1461 GVVMDLATGSAQNGLGGVDSLSNFENVTGSAYADKLSGNALDNVLDGGRGNDILDGRGGN 1520 L + N L G D F+ S + L G ++ L G G D+LDG G+ Sbjct: 783 DK---LIGVAGNNYLNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGD 839 Query: 1521 DVLIGGAGNDTYLFDLGYGVDRIVENDLTAGNTDTVLFGAGIRVQQLWFSRAGDDLIVAM 1580 D+L GG GND Y + GYG I ++ G D + A I + + F R G+DLI+ Sbjct: 840 DLLKGGYGNDIYRYLSGYGHHIIDDD---GGKEDKLSL-ADIDFRDVAFKREGNDLIMYK 895 Query: 1581 P-------GTADRLTVTNWFL-----GAQYQVEIFQTASGALLHAAGVSALVD 1621 G + +T NWF + +++E SG ++ + ++ Sbjct: 896 GEGNVLSIGHKNGITFRNWFEKESGDISNHEIEQIFDKSGRIITPDSLKKALE 948 Score = 95.0 bits (236), Expect = 2e-21 Identities = 57/219 (26%), Positives = 96/219 (43%), Gaps = 31/219 (14%) Query: 718 NELIASNYG-DTLIGGAWKTVLRGGAGHDTLVVTGTGYYMDGGGGSDTVSYAQWQRAVSA 776 ++LI N G D L G L GG G D L GG G+D + ++ Sbjct: 746 DDLIEGNDGNDRLYGDKGNDTLSGGNGDDQL---------YGGDGNDKLIGVAGNNYLNG 796 Query: 777 SLVSGSDDLGSTLAGIENLVGSGWA--DRLTGNGGGNRLDGGAGDDLLVGGGGNDVYVFG 834 G D+ + V G D+L G+ G + LDGG GDDLL GG GND+Y + Sbjct: 797 G--DGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYL 854 Query: 835 RGYGSDTVQNGIAANGGASSMIRVSAGIGIGDLWYERRGDDLL-------IRILGTKDTL 887 GYG I +GG + ++ I D+ ++R G+DL+ + +G K+ + Sbjct: 855 SGYGHHI----IDDDGGKEDKLSLA-DIDFRDVAFKREGNDLIMYKGEGNVLSIGHKNGI 909 Query: 888 ALQGWYQEAFR-----KVAILELQGGLRLDAAAIESLVE 921 + W+++ ++ + + G + +++ +E Sbjct: 910 TFRNWFEKESGDISNHEIEQIFDKSGRIITPDSLKKALE 948 Score = 59.2 bits (143), Expect = 2e-10 Identities = 43/184 (23%), Positives = 66/184 (35%), Gaps = 53/184 (28%) Query: 1425 VIQGGAGNDRIAGGAGNNTLDGGAGIDTVDYSGAGAGVVMDLATGSAQNG---------- 1474 G G+D++ AG+ + G G D V Y G + T + + G Sbjct: 613 ESHLGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGG 672 Query: 1475 -------------------------------------LGGVDSLSNFENVTGSAYADKLS 1497 L D+L + E + G+ ADK Sbjct: 673 DVKVLQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFF 732 Query: 1498 GNALDNVLDGGRGNDILDGRGGNDVLIGGAGNDTYLFDLGYGVDRIVENDLTAGNTDTVL 1557 G+ ++ G G+D+++G GND L G GNDT G G D++ GN D ++ Sbjct: 733 GSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDT--LSGGNGDDQL---YGGDGN-DKLI 786 Query: 1558 FGAG 1561 AG Sbjct: 787 GVAG 790 Score = 45.0 bits (106), Expect = 4e-06 Identities = 41/186 (22%), Positives = 68/186 (36%), Gaps = 19/186 (10%) Query: 1669 VLIGGAGDDTLYGHGGDDKLHGGDGDDTLYGG---------DGIDHLYGGAGRNTLVGGA 1719 G GDD ++ G ++ G G D +Y DG G T V G Sbjct: 613 ESHLGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGG 672 Query: 1720 GSDVYH--VDSADDVIIELPDQGTDRVFATVSYTLADNVEHLHLEGDQAIDGTGNGGNNL 1777 V V + + + ++ R + + E +L + + GT + Sbjct: 673 DVKVLQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTR--ADK 730 Query: 1778 LLGNGAANTLNGGGGDDTLNGGGGDDTLIGGDGNDRYVIARDSGMDRVIEDDDTAGNNDV 1837 G+ + +G GDD + G G+D L G GND ++ +G D++ ND Sbjct: 731 FFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGND--TLSGGNGDDQL----YGGDGNDK 784 Query: 1838 VAFGAG 1843 + AG Sbjct: 785 LIGVAG 790 Score = 41.9 bits (98), Expect = 4e-05 Identities = 28/95 (29%), Positives = 39/95 (41%), Gaps = 14/95 (14%) Query: 1938 VNGPLTLSGTAGDDILE------------GASNNDVLWGLDGDDILIGNDGDDHLHGGTG 1985 V G L+G GDD + G ND L+G +G D+L G +GDD L GG G Sbjct: 788 VAGNNYLNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYG 847 Query: 1986 ANTLIGGK--GNDVYYIDSPLDRIIELAGEGGDRV 2018 + G+ + D + + LA V Sbjct: 848 NDIYRYLSGYGHHIIDDDGGKEDKLSLADIDFRDV 882 Score = 31.9 bits (72), Expect = 0.043 Identities = 32/140 (22%), Positives = 56/140 (40%), Gaps = 18/140 (12%) Query: 1966 DGDDILIGNDGDDHLHGGTGANTLIGGKGNDVYY-IDSP---------LDRIIELAGEGG 2015 DGDD + + G +++ G G + + K + Y ID + R++ + Sbjct: 618 DGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGGDVKVL 677 Query: 2016 DRVESTISFTLPEHVEGLALKGS--GAINGTGNDATNTL------LGNNAANVLSAGKGN 2067 V ++ + E + ING T+ L +G A+ K Sbjct: 678 QEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFFGSKFT 737 Query: 2068 DLINGMDGDDILIGGLGSDR 2087 D+ +G DGDD++ G G+DR Sbjct: 738 DIFHGADGDDLIEGNDGNDR 757
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 460 bits (1185), Expect = e-137 Identities = 232/916 (25%), Positives = 368/916 (40%), Gaps = 118/916 (12%) Query: 52 ALPLLIAAALPGTARAGYASIEIPYQTYRDFAENKGAFRPGALGIPIYDKSGSLRG-SLS 110 + L +A AL A ++ YQ +RDFAENKG F GA + + DK+ G +L Sbjct: 10 FIALTVAYALTPYTEAALVRDDVDYQIFRDFAENKGKFSVGATNVLVKDKNNKDLGTALP 69 Query: 111 DVIPFIDFSSVSDNNAIGTLIAPQYIVGVAHNG---------------------PHDSTR 149 + IP IDFS V + I TLI PQY+VGV H H Sbjct: 70 NGIPMIDFSVVDVDKRIATLINPQYVVGVKHVSNGVSELHFGNLNGNMNNGNAKAHRDVS 129 Query: 150 LAGATYSQIRRDVHPD-------YHRERDWTQEWDFDVTRLGKLVTDATPIATFPVPRTS 202 Y + ++ +P ++ + D+ + RL K VT+ PI Sbjct: 130 SEENRYFSVEKNEYPTKLNGKTVTTEDQTQKRREDYYMPRLDKFVTEVAPIE-------- 181 Query: 203 TPLLSLGDPDLWTEEEKRKFPLFYRVGMGIQFVGDHPEHGHNPMTGALEPG--LHELGYA 260 S D T ++ K+P F R+G G QF+ ++ + G L +G A Sbjct: 182 ---ASTASSDAGTYNDQNKYPAFVRLGSGSQFIYKKGDNYSLILNNHEVGGNNLKLVGDA 238 Query: 261 YKWATGGIVTPTWSNETFVIARGDNGL-------------LPSFVQHGDSGSPLFAWDAE 307 Y + G +I G++ L ++ GDSGSPLF +D E Sbjct: 239 YTYGIAGTPYKVNHENNGLIGFGNSKEEHSDPKGILSQDPLTNYAVLGDSGSPLFVYDRE 298 Query: 308 HRRWVLAGVAADLKIPSGEPGYVYWSHLPADFLHSVFDKDNDPEVVFTEGKGPLRWAFDS 367 +W+ G D + + W+ + F V +KD+ K +++ S Sbjct: 299 KGKWLFLGSY-DFWAGYNKKSWQEWNIYKSQFTKDVLNKDSA--GSLIGSKTD--YSWSS 353 Query: 368 AQGAGHLTQQGRQFAMHGYKKTPGLAYAGGNGALDFAGLDAGRNLSLRSEGGKGVGQITL 427 +T + + + G++++ +G G +TL Sbjct: 354 NGKTSTITGGEKSLNVDLADGKDKP--------------NHGKSVTF-----EGSGTLTL 394 Query: 428 QDSVNQGAGSLTFHNSYVVSPETD-QTWMGGGIDVREGATVVWRVNGVAGDNLHKIGPGT 486 ++++QGAG L F Y V +D TW G G+ V EG TV W+V+ D L KIG GT Sbjct: 395 NNNIDQGAGGLFFEGDYEVKGTSDNTTWKGAGVSVAEGKTVTWKVHNPQYDRLAKIGKGT 454 Query: 487 LTIEGKGVNPGGLKVGDGQVILSQRPDDDGHVQAFDGITLSSGRAEVVLGDGRQVDPDHI 546 L +EG G N G LKVGDG VIL Q+ + G AF + + SGR+ +VL D +QVDP+ I Sbjct: 455 LIVEGTGDNKGSLKVGDGTVILKQQTNGSGQ-HAFASVGIVSGRSTLVLNDDKQVDPNSI 513 Query: 547 KWGARGGVLNLNGNDITFNRLHANAKDHGAAITNTATKTAA-MTI---NLTPMPPPTVSD 602 +G RGG L+LNGN +TF+ + D GA + N A+ +TI +L P Sbjct: 514 YFGFRGGRLDLNGNSLTFDHIRNI--DDGARLVNHNMTNASNITITGESLITDPNTITPY 571 Query: 603 SIRMPVRA------GTGQRGDLYKQG--LSYFVLKQD-SFGAVPTYGSQASDDYWEYAGQ 653 +I P G LY +Y+ L++ S + S S++ W Y G+ Sbjct: 572 NIDAPDEDNPYAFRRIKDGGQLYLNLENYTYYALRKGASTRSELPKNSGESNENWLYMGK 631 Query: 654 SFAAALEKANERKREYFPGQNEFIF---SGTVRGNIDVGV-ASPSKTVFIADGGMDLGEN 709 + A F G GN++V + F+ GG +L Sbjct: 632 TSDEAKRNVMNHINNERMNGFNGYFGEEEGKNNGNLNVTFKGKSEQNRFLLTGGTNL-NG 690 Query: 710 TFTQRQGELVLQGHPVIHAINTPDEARKLLDLGDDSVRTQSVSFDQPDWESRKFAIRKLA 769 T +G L L G P HA + + D + + DW +R F + Sbjct: 691 DLTVEKGTLFLSGRPTPHARDIAGISST---KKDPHFAENNEVVVEDDWINRNFKATTMN 747 Query: 770 LS-DTTFRLSRN-ATLLGDIVA-ERARVVLGSPL--LYLNKNDG-GELPQEPVKGTSIAN 823 ++ + + RN A + +I A +A+V +G ++D G + K + A Sbjct: 748 VTGNASLYSGRNVANITSNITASNKAQVHIGYKTGDTVCVRSDYTGYVTCTTDKLSDKAL 807 Query: 824 TDADKSRYQGTVALSDHSTLDIHEK--FAGAVDARDSAINVFSDQA-ALTGYSR-----F 875 + + +G V L++ + + + F +S + + + LTG S Sbjct: 808 NSFNPTNLRGNVNLTESANFVLGKANLFGTIQSRGNSQVRLTENSHWHLTGNSDVHQLDL 867 Query: 876 TASALTLHAGAHLQGT 891 + L++ + Sbjct: 868 ANGHIHLNSADNSNNV 883
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 57.1 bits (138), Expect = 3e-11 Identities = 82/373 (21%), Positives = 135/373 (36%), Gaps = 73/373 (19%) Query: 21 PALAATSTSSSVQLYGLIDTGLQYLSN----GPSGNSKTGMSTGNLSGSRWGLRGTEDLG 76 AL + + V LYG I G++ + G S + GS+ G +G EDLG Sbjct: 11 AALPVAAMAD-VTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLGSKIGFKGQEDLG 69 Query: 77 DGLSTVFVLE-----NGFDSGNGTTMQGGRLFGRQAYVGLSSKSLGRLTLGRHNTLMIDW 131 +GL ++ +E G DSG G RQ+++GL G+L +GR N+++ D Sbjct: 70 NGLKAIWQVEQKASIAGTDSGWGN---------RQSFIGL-KGGFGKLRVGRLNSVLKDT 119 Query: 132 MSKYNPFDNAN-----FSIKRPDPAF-SDRTDNAVMYVGKFGPVSVGGYYSFGWNNEQSF 185 NP+D+ + I P+ S R D+ +F +S Y+ N+ Sbjct: 120 -GDINPWDSKSDYLGVNKIAEPEARLISVRYDSP-----EFAGLSGSVQYAL--NDNAGR 171 Query: 186 DDKTLGRMLGGGVRYQSGGLDAGVLYHSKNADKPAKGANSDNREDRIVAGLSYDFEGV-- 243 + G Y++GG K + + N + + YD + + Sbjct: 172 HN---SESYHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIH-RLVSGYDNDALYA 227 Query: 244 KVYAGYRWLEQKLTQRTYKNNL-TWLGVTYL-PVQNNRLSLAVYHLNDSVCDDMNNAVCP 301 V + + KL + Y +N T + T N ++ H Sbjct: 228 SVAVQQQ--DAKLVEENYSHNSQTEVAATLAYRFGNVTPRVSYAHGFK------------ 273 Query: 302 AAQAAGTGQKSTM--FVLGNEYDLSKRTTVYAVAAYAVNDDKSAQSVVGGKYGANVEPGK 359 T + V+G EYD SKRT+ A + K+ + Sbjct: 274 -GSFDATNYNNDYDQVVVGAEYDFSKRTSALVSAGWLQEGKGE------SKFVSTA---- 322 Query: 360 NQLGLNLGLRHRF 372 +GLRH+F Sbjct: 323 ----GGVGLRHKF 331
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.6 bits (71), Expect = 0.002 Identities = 11/23 (47%), Positives = 14/23 (60%) Query: 39 TVLALLGPSGCGKSTLLKSLAGL 61 + L G G GKSTL+ +L GL Sbjct: 597 YSVVLEGTGGIGKSTLINTLVGL 619
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 66.0 bits (161), Expect = 4e-14 Identities = 34/162 (20%), Positives = 68/162 (41%), Gaps = 17/162 (10%) Query: 17 AAMVLLVDDQVMVGEAIRRALATEGNIDFHYCSDPYKALTVAVQTRPTVILQDLVLPGVD 76 A +L+ DD + + +AL+ G D S+ +++ D+V+P + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAG-YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 77 GLSLVQEYRSHPVTRDIPIIVLSTKEDPAIKSAAFAAGANDYLVK---LPDSIELVAR-- 131 L+ + D+P++V+S + A GA DYL K L + I ++ R Sbjct: 62 AFDLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 132 ---------IRYHSRSYLALVQRDEAYQALRQSQQQLLESNM 164 + S+ + LV R A Q + + +L+++++ Sbjct: 120 AEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDL 161
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 44.1 bits (104), Expect = 5e-07 Identities = 36/172 (20%), Positives = 65/172 (37%), Gaps = 20/172 (11%) Query: 6 ETLRRVIALEPGLEVAWVASNGLEAVQQCAQDRPDVVLMDLVMPVMDGVEATRRIMAETP 65 L + ++ G +V + SN + A D+V+ D+VMP + + RI P Sbjct: 17 TVLNQALSRA-GYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKARP 74 Query: 66 -CAIVVVTVDVARHTARVFDAMGYGALDAADTPVVGG----------GDLRSAAAPLLRK 114 ++V++ TA A GA D P + + + L Sbjct: 75 DLPVLVMSAQNTFMTA--IKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDD 132 Query: 115 IRNIGWLIGRYGNNRTALTPVVRDAAQAGPSQ-GLLVIGASAGGPATLAQLL 165 ++ L+GR A+ + R A+ + L++ G S G +A+ L Sbjct: 133 SQDGMPLVGR----SAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 74.9 bits (184), Expect = 4e-16 Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 3/117 (2%) Query: 629 RKRVLVVDDSLTVRELERKLLLNRGFDVAVAVDGMDGWNMLRSEAFDLVVTDVDMPRMDG 688 +LV DD +R + + L G+DV + + W + + DLVVTDV MP + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 689 IELVSRIKADPKLQSLPVMVVSYKDREEDRRRGLDAGADYYLAKGSFHDDALLDAVE 745 +L+ RIK LPV+V+S ++ + + GA YL K F L+ + Sbjct: 63 FDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPK-PFDLTELIGIIG 116
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 28.4 bits (63), Expect = 0.047 Identities = 19/115 (16%), Positives = 30/115 (26%), Gaps = 1/115 (0%) Query: 218 TQERAVTVLRRFARHDGILFVGPAET-SLMTGRRLPAVPLARAFAFRAEPAPPTEAAPAR 276 T V L A+ + V PA+ + P + P PP EA Sbjct: 35 TSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVI 94 Query: 277 TASAASGRATPPPVVAPRAAQPWTPAARPQPYTPAAPARPHAASLAPHGTTAQAG 331 + P PV + +P +P P + + Sbjct: 95 EKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKP 149
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 78.2 bits (192), Expect = 2e-19 Identities = 69/257 (26%), Positives = 111/257 (43%), Gaps = 26/257 (10%) Query: 2 ALVTGSTSGIGAAIARRLSRDGYAVVLHSRQSAEAGRALAAELGTAVYVQADLAVDADRV 61 A +TG+ GIG A+AR L+ G A + + E + + L D Sbjct: 11 AFITGAAQGIGEAVARTLASQG-AHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 62 RLVREAVAAW----GRLDVLVNNAGISRVIAHGDLAAATPAVWHEMHEVHVVAPFRLVAE 117 + E A G +D+LVN AG+ R G + + + W V+ F Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRP---GLIHSLSDEEWEATFSVNSTGVFNA--- 123 Query: 118 AQAALSAAAARGRPGCVVNVSSHAGVRPKGASIPYAAAKAALNHVTRLLAVSLAPS-IRV 176 +++ R R G +V V S+ P+ + YA++KAA T+ L + LA IR Sbjct: 124 SRSVSKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 177 NAVAPGLVDTPLTR-----DWTQAQQL------WRERAPMRRAAQPDDIAQAVAWLA--Q 223 N V+PG +T + + Q + ++ P+++ A+P DIA AV +L Q Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 224 SDYLTGEILLSDGGLNL 240 + ++T L DGG L Sbjct: 243 AGHITMHNLCVDGGATL 259
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 58.9 bits (142), Expect = 8e-13 Identities = 21/155 (13%), Positives = 57/155 (36%), Gaps = 3/155 (1%) Query: 14 QPQQARSAELVAAILQAGAQVLAKEGAARFTTARVAEKAGVSIGSLYQYFPNKAAILYRL 73 + + + E IL ++ +++G + + +A+ AGV+ G++Y +F +K+ + + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 74 QTQEWQQTSDLLRRLLEDARHAPPQRLRNLVHAFVR---SECEEAVMRVALNDAAPLYRD 130 +L P LR ++ + +E ++ + + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 131 APEARATKEEGGRIVLAFLEEALPNASDATRVLAG 165 + + +E+ L + +A + A Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPAD 157
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 100 bits (251), Expect = 7e-25 Identities = 82/387 (21%), Positives = 139/387 (35%), Gaps = 14/387 (3%) Query: 47 IALPAIARDLGGSPVALNWITNAFMLVFGSSLLVAGALADRYGRRRVFLAGAAIFIAASL 106 ++LP IA D P + NW+ AFML F V G L+D+ G +R+ L G I S+ Sbjct: 35 VSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSV 94 Query: 107 -GLVHAPDIVAFDLLRAAQGLGGAAIFSGGAAALAQAFDGPGRMRAFSLLGASFGAGLSF 165 G V + R QG G AA + +A+ R +AF L+G+ G Sbjct: 95 IGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGV 154 Query: 166 GPIASALLIERYGWRSIFLLVIGLAAVALLLGARCLRESRDPAAGRLDWPGAATFSAALA 225 GP ++ W + L+ + L +E R G D G S + Sbjct: 155 GPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVR--IKGHFDIKGIILMSVGIV 212 Query: 226 LLTWGIMRAPQSGWGDPSTLAMLAAAVALFAAFGVIELRAVRPMLDLTLFRYPRFLGVQL 285 S L +V F F + P +D L + F+ L Sbjct: 213 FFMLFTTSYSIS---------FLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVL 263 Query: 286 LAAAPAYAFVVLLILLPVRFIAVDGLGEIEAGR-MMIALSAPLLLLPIVAGQLTRWLAPA 344 + ++P V L E G ++ + +++ + G L P Sbjct: 264 CGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPL 323 Query: 345 LICGAGLLLAAAGLAWLSLAMTAGQVTALVGPMLLIGIGISLPWGLMDGLAVSVVPVERA 404 + G+ + S + + + ++G G+S ++ + S + + A Sbjct: 324 YVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG-GLSFTKTVISTIVSSSLKQQEA 382 Query: 405 GMATGIFSTTRVAGEGVALAVVSALLT 431 G + + T EG +A+V LL+ Sbjct: 383 GAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 46.4 bits (110), Expect = 1e-07 Identities = 22/130 (16%), Positives = 45/130 (34%), Gaps = 7/130 (5%) Query: 23 RTVELRSRVGGTVDAVSVPEGSLVRQGQPLFQIDPRPFQVALDTALAQLRQAQALADQAQ 82 R+ E++ V + V EG VR+G L ++ + + L QA+ + Q Sbjct: 95 RSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQ 154 Query: 83 TDFDRAER------LVSTGAVSRKVHDEAASTRRARLAQVQVAKAAVAAARLDLSYARIT 136 E + + V +E + L + Q + + +L+ + Sbjct: 155 ILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTS-LIKEQFSTWQNQKYQKELNLDKKR 213 Query: 137 APIAGRVDRV 146 A + R+ Sbjct: 214 AERLTVLARI 223 Score = 32.5 bits (74), Expect = 0.003 Identities = 18/100 (18%), Positives = 42/100 (42%), Gaps = 3/100 (3%) Query: 61 QVALDTALAQLRQAQALADQAQTDFDRAERLVSTGAVSRKVHDEAASTRRARLAQVQVAK 120 + A+ +LR ++ +Q +++ A+ V++ +E R + + Sbjct: 258 ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQL--VTQLFKNEILDKLRQTTDNIGLLT 315 Query: 121 AAVAAARLDLSYARITAPIAGRVDRVMV-TEGNLVSGGTA 159 +A + I AP++ +V ++ V TEG +V+ Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET 355
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1055 bits (2731), Expect = 0.0 Identities = 433/1041 (41%), Positives = 649/1041 (62%), Gaps = 19/1041 (1%) Query: 6 FFIARPIFAIVLSLLMLLAGAIAFWQLPLSEYPAVTPPTVQVTASYPGANPEVIADTVAA 65 FFI RPIFA VL++++++AGA+A QLP+++YP + PP V V+A+YPGA+ + + DTV Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 66 PLEQVINGVEGMLYMNSQMATDGRMVLTIAFKQGTDPDMAQIQVQNRVSRALPRLPEEVQ 125 +EQ +NG++ ++YM+S + G + +T+ F+ GTDPD+AQ+QVQN++ A P LP+EVQ Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ 123 Query: 126 RIGVVTQKTSPDVLMVVHIVSPQKRYDSLYLSNFAIRQVRDELARLPGVGDVLVWGAGEY 185 + G+ +K+S LMV VS +S++ V+D L+RL GVGDV ++G +Y Sbjct: 124 QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG-AQY 182 Query: 186 SMRVWLDPSRVATRGLTASDVVAALREQNVQVAAGSVGQQPDTSA-AFQVTVNTLGRLAS 244 +MR+WLD + LT DV+ L+ QN Q+AAG +G P ++ R + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 245 EEQFGDIVVKTGADGQVTRLRDIARVSLGADAYTLRSLIDGESAPALQIIQSPGANAIDV 304 E+FG + ++ +DG V RL+D+ARV LG + Y + + I+G+ A L I + GANA+D Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 305 SNAVRAKMETLQQGFPQDISYRIAYDPTVFVRASLQSVAVTLLEAVILVVLVVVLFLQTW 364 + A++AK+ LQ FPQ + YD T FV+ S+ V TL EA++LV LV+ LFLQ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 365 RASIIPLVAVPVSLVGTFAVMHMFGFSLNTLSLFGLVLSIGIVVDDAIVVVENVERHMA- 423 RA++IP +AVPV L+GTFA++ FG+S+NTL++FG+VL+IG++VDDAIVVVENVER M Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 424 LGERPIDAARKAMDEVTGPILAITSVLAAVFIPSAFLSGLQGEFYRQFALTIAISTVLSA 483 P +A K+M ++ G ++ I VL+AVFIP AF G G YRQF++TI + LS Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 484 INSLTLSPALAAMLLRPHHEAARADWLTRVIDRALGGFFRRFNRFFDRASQAYVVAVRRA 543 + +L L+PAL A LL+P ++ GGFF FN FD + Y +V + Sbjct: 483 LVALILTPALCATLLKP---------VSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKI 533 Query: 544 VRGSAIVLLLYAGFTGLTWLGFNQVPNGFVPAQDKYFLVGIAQLPSGASLDRTEAVVKQM 603 + + LL+YA + F ++P+ F+P +D+ + + QLP+GA+ +RT+ V+ Q+ Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQV 593 Query: 604 SEIALA--EPGVESVVAFPGLSVNGPVNVPNSALMFAMLKPFDERQDAALSANAIAGKLM 661 ++ L + VESV G S +G N+ + F LKP++ER SA A+ + Sbjct: 594 TDYYLKNEKANVESVFTVNGFSFSG--QAQNAGMAFVSLKPWEERNGDENSAEAVIHRAK 651 Query: 662 GKFSQIPDGFVGIFPPPPVPGLGAMGGFKLQIEDRAALGFEALAQAQGQIMARAMQAP-E 720 + +I DGFV F P + LG GF ++ D+A LG +AL QA+ Q++ A Q P Sbjct: 652 MELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPAS 711 Query: 721 LANMLASFQTNAPQLQVDVDRVKAKSLGVSLTDVFETLQINLGSLYVNDFNRFGRTYRVM 780 L ++ + + Q +++VD+ KA++LGVSL+D+ +T+ LG YVNDF GR ++ Sbjct: 712 LVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLY 771 Query: 781 AQADAPFRMQAEDIGLLKVRNADGHMIPLSAFVTLTRGSGPDRVIHYNGFPSADISGGPA 840 QADA FRM ED+ L VR+A+G M+P SAF T G R+ YNG PS +I G A Sbjct: 772 VQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAA 831 Query: 841 PGYSSGQATDAIEQIVRETLPDGMVYEWTDLVYQEKQAGNSALYIFPLAVLLAFLILAAQ 900 PG SSG A +E + + LP G+ Y+WT + YQE+ +GN A + ++ ++ FL LAA Sbjct: 832 PGTSSGDAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAAL 890 Query: 901 YNSWSLPFAVLLIAPMALLSAIGGVWLSGGDNNIFTQIGFVVLVGLAAKNAILIVEFAR- 959 Y SWS+P +V+L+ P+ ++ + L N+++ +G + +GL+AKNAILIVEFA+ Sbjct: 891 YESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKD 950 Query: 960 AKEDEGADPLAAVLEAARLRLRPILMTSFAFIAGVVPLVLASGAGAEMRHAMGIAVFAGM 1019 E EG + A L A R+RLRPILMTS AFI GV+PL +++GAG+ ++A+GI V GM Sbjct: 951 LMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGM 1010 Query: 1020 LGVTLFGLLLTPVFYVVVRKL 1040 + TL + PVF+VV+R+ Sbjct: 1011 VSATLLAIFFVPVFFVVIRRC 1031 Score = 98.4 bits (245), Expect = 7e-23 Identities = 76/435 (17%), Positives = 140/435 (32%), Gaps = 44/435 (10%) Query: 643 FDERQDAALSANAIAGKLMGKFSQIPDGFVGIFPPPPVPGLGAMGGFKLQIEDRAALGFE 702 F D ++ + KL +P + + + + GF Sbjct: 94 FQSGTDPDIAQVQVQNKLQLATPLLPQEV----QQQGISVEKSSSSYLMVA------GFV 143 Query: 703 ALAQAQGQIMARAMQAPELANML------ASFQTNAPQLQ--VDVDRVKAKSLGVSLTDV 754 + Q A + + L Q Q + +D ++ DV Sbjct: 144 SDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDV 203 Query: 755 FETLQIN--------LGSLYVNDFNRFGRTYRVMAQADAPFRMQAEDIGLLKVR-NADGH 805 L++ LG + + + P E+ G + +R N+DG Sbjct: 204 INQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNP-----EEFGKVTLRVNSDGS 258 Query: 806 MIPLSAFVTLTRGSGPDRVI-HYNGFPSADISGGPAPGYSSGQATDAIEQIV---RETLP 861 ++ L + G VI NG P+A + A G ++ AI+ + + P Sbjct: 259 VVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFP 318 Query: 862 DGM----VYEWTDLVYQEKQAGNSALYIFPLAVLLAFLILAAQYNSWSLPFAVLLIAPMA 917 GM Y+ T V L+ A++L FL++ + + P+ Sbjct: 319 QGMKVLYPYDTTPFVQLSIHEVVKTLFE---AIMLVFLVMYLFLQNMRATLIPTIAVPVV 375 Query: 918 LLSAIGGVWLSGGDNNIFTQIGFVVLVGLAAKNAILIVE-FARAKEDEGADPLAAVLEAA 976 LL + G N T G V+ +GL +AI++VE R ++ P A ++ Sbjct: 376 LLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSM 435 Query: 977 RLRLRPILMTSFAFIAGVVPLVLASGAGAEMRHAMGIAVFAGMLGVTLFGLLLTPVFYVV 1036 ++ + A +P+ G+ + I + + M L L+LTP Sbjct: 436 SQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCAT 495 Query: 1037 VRKLALRRAPSRARA 1051 + K Sbjct: 496 LLKPVSAEHHENKGG 510
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 30.1 bits (67), Expect = 0.023 Identities = 29/130 (22%), Positives = 44/130 (33%), Gaps = 5/130 (3%) Query: 209 LRLTTDTLATQQRSYDLTAQLARVGNATQLDLRLAEITLRAAEADRAAYTRQAARDRNAL 268 L++ +TL + S + A A R AE R A RAA T + + + Sbjct: 200 LQIRMNTLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAANTYAMPANGSVV 259 Query: 269 VLLLGQPLTPALARQLDQANTLPDDI-----VPATLPSGLPAQLLARRPDLRAAEQRLRA 323 G+ L A + D I V A+ PS + + R AEQ Sbjct: 260 ATAAGRGLIQVAQGAASLAQAISDAIAVLGRVLASAPSVMAVGFASLTYSSRTAEQWQDQ 319 Query: 324 ANANIGAARA 333 ++ A Sbjct: 320 TPDSVRYALG 329
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 33.0 bits (75), Expect = 0.003 Identities = 24/148 (16%), Positives = 43/148 (29%), Gaps = 9/148 (6%) Query: 297 MTLALAPLAAAGLLVGAVHYAVTQPEVVYDIPAELRLGSDEFQS-GLSEPPLGGLAEPPT 355 L+ ++ G ++ +V Q V ++PA + S + EPP P Sbjct: 16 WPTLLSVCIHGAVVAGLLYTSVHQ---VIELPAPAQPISVTMVAPADLEPPQAVQPPPEP 72 Query: 356 DGLAEPPADGLAEPPASGVTEPAASGLAEPPGT-----DGGGQAATAPGAPQRAGADAAS 410 EP + + EPP P + P + A + Sbjct: 73 VVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENT 132 Query: 411 GSGAPADTASTSPTGGEKPAPRGFWIFL 438 P + +T+ T + L Sbjct: 133 APARPTSSTATAATSKPVTSVASGPRAL 160
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.5 bits (167), Expect = 2e-16 Identities = 39/194 (20%), Positives = 72/194 (37%), Gaps = 11/194 (5%) Query: 24 AEVRLDELMGAAQALFLEKGVEATTISEITEAAGVAKGTFYVYFPSKQEMLVALGERYVR 83 A+ ++ A LF ++GV +T++ EI +AAGV +G Y +F K ++ + E Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 84 EFVERLERAVAACAEDDWEGRLRAWIHANVSMYLRTYR--VHDIVFTHPHHHA------- 134 E A D IH S R + +I+F Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 135 REGHTENQVVTQLQGILRAGAQAGAWRLD-NPRMMALLIYAGVHCATDDAILSRQS-DAT 192 + + + +++ L+ +A D R A+++ + ++ + + QS D Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLK 188 Query: 193 DFARGIADAYLRML 206 AR L M Sbjct: 189 KEARDYVAILLEMY 202
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 94.3 bits (234), Expect = 1e-21 Identities = 206/914 (22%), Positives = 316/914 (34%), Gaps = 126/914 (13%) Query: 202 TLHGGKITTTGNYGDGISVRGANALVSVYGTEINVGAGVGARLEGGRFVMDGGSLTAGGS 261 T G I +G GI + A E+ G V G L+ G Sbjct: 63 TASGTTIKVSGRQAQGILLENPAA-------ELQFRNGS---------VTSSGQLSDDGI 106 Query: 262 AVMLSSGTGAASSVDIRNATLTST----GDFGYGININAKDTSAAVENVSISALG--YYG 315 L + T A + +ATL + D G + + + A++ + ++ G Sbjct: 107 RRFLGTVTVKAGKLVADHATLANVGDTWDDDGIALYVAGEQAQASIADSTLQGAGGVQIE 166 Query: 316 TGVWLPSTGTSFTATGFDLTSSHVGVDNRAG--RVTLVDGNVTTRDANAHGLYVSREYGS 373 G + ++ G + + RV L D NVT A+ VS S Sbjct: 167 RGANVTVQRSAIVDGGLHIGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPAAVSVLGAS 226 Query: 374 SATIKATKVNVKTRGDGAVGVLARASGAAIELLDASVTTEGASAYGLFASGS----GVSL 429 T+ + G A GV A GA + L A++ A A G G+ V Sbjct: 227 ELTLDGGHIT----GGRAAGVAA-MQGAVVHLQRATIRRGDAPAGGAVPGGAVPGGAVPG 281 Query: 430 SARNTQISTSGANATGLSVSNRAAVTLDNTGFTLAGAGAHGIWSYVTAAGVSNTVTLRNG 489 G+ VS ++V L + GA G VT+ G Sbjct: 282 GFGPGGFGPVLDGWYGVDVSG-SSVELAQSIVEAPELGAAI------RVGRGARVTVSGG 334 Query: 490 SRIDTQDGVGLLASGGGHTFLVSDS--DITARAGGDVGSGVLLHSRAVTVTSGGVSTVIE 547 S + G ++ +GG F + IT +AG LL+ T+ Sbjct: 335 S-LSAPHG-NVIETGGARRFAPQAAPLSITLQAGAHAQGKALLYRVLPEPVK---LTLTG 389 Query: 548 SEQVTLDATNARLTGDVLADSGTVDVSLANGSTLNGALVQRGTGRINGLTLDGTSTWIVR 607 D L G +DV+LA+ + GA T ++ L++D +TW++ Sbjct: 390 GADAQGDIVATELPSIPGTSIGPLDVALASQARWTGA-----TRAVDSLSIDN-ATWVMT 443 Query: 608 GDSSLATLS--NAGTVAFAAPAGGAGFKTLTVNNYVGGGTLVLNTQLGDDASPTDKLVID 665 +S++ L + G+V F PA FK LTVN G G +N D +DKLV+ Sbjct: 444 DNSNVGALRLASDGSVDFQQPAEAGRFKVLTVNTLAGSGLFRMNVFA--DLGLSDKLVVM 501 Query: 666 GGTTSGNTALRIVNAGGSGGQTTYGIRVVETINGGTTTADAFHLDSGSTGYRASARTVSL 725 + + V GS + + +V+T G T + D V + Sbjct: 502 QDASGQHRLW--VRNSGSEPASANTLLLVQTPLGSAATFTLANKDG----------KVDI 549 Query: 726 NGYDYSLVRGGNGAVAPDWYLTSDYTPPVTPPDPVDPINPTDPGDPTGPVTPPDPVLPGG 785 Y Y L GNG W L PP P P P P P P P P G Sbjct: 550 GTYRYRLAANGNGQ----WSLVGAKAPP--APKPAPQPGPQPPQPPQPQPEAPAPQPPAG 603 Query: 786 PGFKNVSPESGAYAGNRLAATRLFTHS--LHDRVPA-YADGDADARHGRGLWARVQGRHD 842 + + G LA+T + S L R+ + DA GRG R Q + Sbjct: 604 RELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRLNPDAGGAWGRGFAQRQQLDNR 663 Query: 843 SGLRMSEGRVDVDTDSAMVQLGGDLLKAPLGREGALYAGLMGGYGDARSRSVSTLMLPGA 902 +G R D A +LG D A G + G + GY Sbjct: 664 AGRRF-------DQKVAGFELGAD--HAVAVAGGRWHLGGLAGYTRGD------------ 702 Query: 903 TQSTHARARGKVSGYAGGVYGTFYANDLTRLGAYADTWIQYGRYTNQ---VSSELGSVR- 958 + G G Y T+ A+ G Y D ++ R N S+ +V+ Sbjct: 703 -RGFTGDGGGHTDSVHVGGYATYIADS----GFYLDATLRASRLENDFKVAGSDGYAVKG 757 Query: 959 -YRSNVWSASLEGGYALKPFAAGSALEALVIEPNAQLVY-----SRYRAQDATLQGTRMR 1012 YR++ ASLE G + + +EP A+L YRA + G R+R Sbjct: 758 KYRTHGVGASLEAGRRF------THADGWFLEPQAELAVFRAGGGAYRAAN----GLRVR 807 Query: 1013 SGDNGSWQSRVGVRLYPQVTPQPGESSVRPFLETNWLHRSD-DPTVRMGSTTLQAQPSRN 1071 S R+G+ + ++ G V+P+++ + L D TV + + Sbjct: 808 DEGGSSVLGRLGLEVGKRIELAGG-RQVQPYIKASVLQEFDGAGTVHTNGIAHRTELRGT 866 Query: 1072 ALELKVGAEGRVGK 1085 EL +G +G+ Sbjct: 867 RAELGLGMAAALGR 880
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 68.3 bits (167), Expect = 8e-14 Identities = 32/160 (20%), Positives = 64/160 (40%), Gaps = 8/160 (5%) Query: 852 RILVAEDNPINQVTMCDQLEQLGCQVTVAPDGAEALAQWNIEPFDVVLTDVNMPRMNGYE 911 ILVA+D+ + + L + G V + + A D+V+TDV MP N ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 912 LAGALRAQGVTVPIIGVTANALKDEEARCKAAGMSNWLVKPIKLSLLWSQLRAVRGEPAA 971 L ++ +P++ ++A + G ++L KP L+ L + + A Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL---IGIIGRALAE 121 Query: 972 PRTAGAAEAASPRAAPPIVGKYREVFLETMTQDLARMEQA 1011 P+ + + P+VG+ M + + + Sbjct: 122 PKRRPSKLEDDSQDGMPLVGRS-----AAMQEIYRVLARL 156
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.9 bits (153), Expect = 8e-13 Identities = 28/153 (18%), Positives = 53/153 (34%), Gaps = 6/153 (3%) Query: 8 KVLVLDDHALQCLHLKDMLQQAGFGHVDTVESAGAALDRISAEGYHLVLMDISMPGMDGV 67 +LV DD A L L +AG+ V +A I+A LV+ D+ MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGY-DVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 68 QFIHELARLNLRPILAVVTACSRRMANSVGLMAKENGFSMLGTFVKPVTGEQIASLADRL 127 + + + + V++A N+ K + KP ++ + R Sbjct: 64 DLLPRIKKARPDLPVLVMSA-----QNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 128 RRRAPDDAQEPQAHRGDTEGLLDRASVESALRD 160 + + D L+ R++ + Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYR 151
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 70.2 bits (172), Expect = 1e-14 Identities = 25/102 (24%), Positives = 46/102 (45%) Query: 802 RILVVEDNVINQLILREQLEHLGCAVTLAGNGEEALQRWRGERFDLVLTDLNMPVVNGYE 861 ILV +D+ + +L + L G V + N + DLV+TD+ MP N ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 862 LARALREGGYDGPLIGLTSSSAAEIAQRGVAAGMTQVLCKPL 903 L +++ D P++ +++ + A + G L KP Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.2 bits (65), Expect = 0.003 Identities = 13/57 (22%), Positives = 24/57 (42%), Gaps = 7/57 (12%) Query: 21 AGPALAAEKKPTAGDISRAI---AYADVMRAFAYSKQATEFKERFDKIGPGPDGLEA 74 + A A ++ AI ++ + F + + E+ +RF K+G D L A Sbjct: 303 SAAAAGL----IASAVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLGYDGDSLLA 355
>PF07675#Cleaved Adhesin Length = 1358 Score = 27.4 bits (60), Expect = 0.017 Identities = 13/33 (39%), Positives = 15/33 (45%) Query: 91 VRSEVLVLGLADDAGDTVLVTPEFDVPNGARLT 123 V S + D LVTPE +PNG LT Sbjct: 677 VSSASYINFEGPQNPDNYLVTPELSLPNGGTLT 709
>PF06580#Sensor histidine kinase Length = 349 Score = 29.8 bits (67), Expect = 0.019 Identities = 20/118 (16%), Positives = 38/118 (32%), Gaps = 27/118 (22%) Query: 295 LPDALLDCAVRN-----LVDNALKY----SPDDKPVEVDAGIVADWLVVTVRDHGSGLTP 345 + A++D V LV+N +K+ P + + + + V + GS Sbjct: 246 INPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALK 305 Query: 346 AQCAQAAEPFWRGHRQVEGAGLGLSIV-ATIAARHGG--MLELTPAVGGGLCGRLSLP 400 E G GL V + +G ++L+ G + +P Sbjct: 306 --------------NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKV-NAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.8 bits (241), Expect = 2e-25 Identities = 41/135 (30%), Positives = 61/135 (45%), Gaps = 4/135 (2%) Query: 2 RILLVEDDASIASAIQAGLGLQGFVVDAVGSLRQADLAVQTSHASACVLDLCLPDGDGVT 61 IL+ +DDA+I + + L G+ V + + V D+ +PD + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LLAKWRARRQDLPVLVLTARSAIAQRVAALRAGADDYVLKPFDLDELAAR----LQALIR 117 LL + + R DLPVLV++A++ + A GA DY+ KPFDL EL L R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 118 RAAGHSADRIDHGRL 132 R + D D L Sbjct: 125 RPSKLEDDSQDGMPL 139
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 596 bits (1537), Expect = 0.0 Identities = 228/847 (26%), Positives = 378/847 (44%), Gaps = 65/847 (7%) Query: 2 CTAQATEFSTGFLNTKDKNNIDLSTFSRDGYIAPGSYLLDIYLDQRLIQGQTLVKAVPVI 61 ++ F+ FL + DLS F + PG+Y +DIYL+ + + + Sbjct: 42 LSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDS 101 Query: 62 GDGTVFCVTPGMVDMLSLKDEFRARLAQVHTAEGGPCIDLDT--PDSRVVYSAEHQSLTL 119 G V C+T + + L + + + C+ L + D+ Q L L Sbjct: 102 EQGIVPCLTRAQLASMGLNTASVSGMNLLAD---DACVPLTSMIHDATAQLDVGQQRLNL 158 Query: 120 TVPQAWLQYQDPDWVPPARWSNGVNGVILDYNVLANRYMPRQGAGSASYTLYGTGGLNLG 179 T+PQA++ + ++PP W G+N +L+YN N R G S L GLN+G Sbjct: 159 TIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIG 218 Query: 180 AWRLRSDYQYNRYDSGGQS--QARFSLPQTYLFRALPQWRSKLTLGQTYLASAIFDPFRF 237 AWRLR + ++ S S + ++ T+L R + RS+LTLG Y IFD F Sbjct: 219 AWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINF 278 Query: 238 AGVTLASDERMLPPSLQGYAPQITGIATSNAEVTVSQNGRLLYQTRVSPGPFVLPALNQY 297 G LASD+ MLP S +G+AP I GIA A+VT+ QNG +Y + V PGPF + + Sbjct: 279 RGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAA 338 Query: 298 -ISGNLDVSLRESDGTKRSWQVSTASVPFMTRKGNLRYQVSLGRPLFGGPSGNHVAKPRF 356 SG+L V+++E+DG+ + + V +SVP + R+G+ RY ++ G KPRF Sbjct: 339 GNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYR---SGNAQQEKPRF 395 Query: 357 MAGEATWGAFNNTSLYGGLIVTDDNYQALALGAGQNMGALGALSADVTRSDARLPYSSAP 416 G ++YGG + D Y+A G G+NMGALGALS D+T++++ LP Sbjct: 396 FQSTLLHGLPAGWTIYGGTQLADR-YRAFNFGIGKNMGALGALSVDMTQANSTLP--DDS 452 Query: 417 RRTGYSYRVNYAKSFDDLGSTLAFMGYRFSGRHFLSMREFI------------------- 457 + G S R Y KS ++ G+ + +GYR+S + + + Sbjct: 453 QHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVK 512 Query: 458 VRSALHGGDFRDEKQSYTVSYSQYIQPLELSVSLSLSRLNYWNDAAANNHYMLSFNKNAR 517 + + +++ ++ +Q + ++ LS S YW + + + N Sbjct: 513 PKFTDYYNLAYNKRGKLQLTVTQQL-GRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTA-- 569 Query: 518 FGPLRNVSLSLSLARTQSVYG-PTQNQVYASLSIPLGDSR-----------QLSYGYQNS 565 +++ +LS + T++ + + +++IP SY + Sbjct: 570 ---FEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHD 626 Query: 566 GGGRMQQNVGY--TDFSNPDTTWNLSAS-DDRDAPDRHQSVSGNIQSRTPYGRAAGDFTL 622 GRM G T + + ++++ + + + R YG A ++ Sbjct: 627 LNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSH 686 Query: 623 QPGQYRSVGLNWYGSVTATAEGAAFGPPSSGNEPRMMIDTDGIAGVQIENGDGV-TNRFG 681 + + G V A A G G P N+ +++ G ++EN GV T+ G Sbjct: 687 SDD-IKQLYYGVSGGVLAHANGVTLGQPL--NDTVVLVKAPGAKDAKVENQTGVRTDWRG 743 Query: 682 IAVVNGVSSYRESNLAVDVNALPDGVDVADAMISQVLTEGAIGYTRVGARHGEQVLGRVE 741 AV+ + YRE+ +A+D N L D VD+ +A+ + V T GAI AR G ++L + Sbjct: 744 YAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTLT 803 Query: 742 LADGSHPPLGALVLSTRSGKTAGMVADGGLVYLNVEPDDREALTVTWGGARECR----LA 797 + P GA+V S S +++G+VAD G VYL+ P + V WG Sbjct: 804 -HNNKPLPFGAMVTS-ESSQSSGIVADNGQVYLSGMP-LAGKVQVKWGEEENAHCVANYQ 860 Query: 798 LPAAAAI 804 LP + Sbjct: 861 LPPESQQ 867
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 23.6 bits (51), Expect = 0.028 Identities = 8/41 (19%), Positives = 17/41 (41%), Gaps = 1/41 (2%) Query: 2 ALAAVMAWCLSLSESACVRYGGWIAGGTLLGMLGLGLWVSR 42 AL + +S+ A +G W+ L G + + + + Sbjct: 208 ALPLSTRVLMGMSD-AVRTFGPWMLLALLAGFMAFRVMLRQ 247
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.2 bits (164), Expect = 3e-14 Identities = 30/140 (21%), Positives = 52/140 (37%), Gaps = 7/140 (5%) Query: 1 MLSYRVLIVDDQLLQREYLKNLFLQAGIAHVETAENGSHALRLLEKQRYDLVLSDLLMPE 60 M +L+ DD R L +AG V N + R + DLV++D++MP+ Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYD-VRITSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 61 LDGVQLIQRLSTYETPPLLAVISSSPKRLIAGASLVAKTLGMRVIDQLSKPAQPQAIIAL 120 + L+ R+ + V+S+ K D L KP +I + Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQ-----NTFMTAIKASEKGAYDYLPKPFDLTELIGI 114 Query: 121 VAK-LKAASRLKAESLVSGQ 139 + + L R ++ Q Sbjct: 115 IGRALAEPKRRPSKLEDDSQ 134
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.2 bits (190), Expect = 1e-16 Identities = 27/117 (23%), Positives = 53/117 (45%) Query: 846 RVLVAEDNPVNRTLLVRQLEELGCEVTLCVDGVETLARWNSDEFDVLITDMNMPLMNGYE 905 +LVA+D+ RT+L + L G +V + + + + D+++TD+ MP N ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 906 LVRTLRARHTKAPIIGLTADALQTQRDAGFAAGLNAWVVKPVDLRTLHDALSTACAR 962 L+ ++ P++ ++A G ++ KP DL L + A A Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 57.5 bits (139), Expect = 5e-12 Identities = 38/183 (20%), Positives = 70/183 (38%), Gaps = 13/183 (7%) Query: 2 TRILLADDHQVVILGVRNVLEGVARHHIVGEALSATELIRKARELTPDIIITDYNMPSED 61 IL+ADD + + L + V +A L R D+++TD MP Sbjct: 4 ATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMPD-- 59 Query: 62 GYGDGLALVQYLRRNFPRVRILIHTMISSPVIVASLYEEGVSGVLFKSGDLAEIL----T 117 + L+ +++ P + +L+ + ++ + E+G L K DL E++ Sbjct: 60 --ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117 Query: 118 ALGALENNQIYRSTPQVLAANHPGGA---QDAATRIARLSPKELEVLRHFLSGTSVGDIA 174 AL + G + Q+ +ARL +L ++ SGT +A Sbjct: 118 ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVA 177 Query: 175 RIM 177 R + Sbjct: 178 RAL 180
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 28.5 bits (63), Expect = 0.038 Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 4/46 (8%) Query: 134 ALPAMYDSMTLVYAKSAFAQPPRSWREM----WDPKYRGKVAVATN 175 A P ++++L+Y K PP++W E+ + K +GK A+ N Sbjct: 131 AYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFN 176
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 59.9 bits (145), Expect = 6e-12 Identities = 32/157 (20%), Positives = 62/157 (39%), Gaps = 1/157 (0%) Query: 18 AFPTIAANLGVPRGDVERTLAAYLIGLALAQVFYGPMADRYGRKPPLMVGLALFMVASLG 77 + P IA + P A+++ ++ YG ++D+ G K L+ G+ + S+ Sbjct: 36 SLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVI 95 Query: 78 CALAGS-VQALTGWRVLQAMGGAAGIVIPRAVIRDHYETHEAARAMSLLMLIMGLAPILA 136 + S L R +Q G AA + V+ + +A L+ I+ + + Sbjct: 96 GFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVG 155 Query: 137 PLAGGQLLGIASWRSLFWVMLAGGAMLMTAVVLIMKE 173 P GG + W L + + + + L+ KE Sbjct: 156 PAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKE 192
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 24.3 bits (52), Expect = 0.030 Identities = 8/30 (26%), Positives = 15/30 (50%) Query: 9 IKLESTAGTGHFYTTTKNKRNMPEKMLIKK 38 + + S +G G FY T +K+++ K Sbjct: 889 LTVNSLSGNGSFYYLTDLSNKQGDKVVVTK 918
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.1 bits (62), Expect = 0.041 Identities = 9/21 (42%), Positives = 11/21 (52%) Query: 35 MLALIGPNGAGKSTCFNVVGG 55 + L G G GKST N + G Sbjct: 598 SVVLEGTGGIGKSTLINTLVG 618
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 29.4 bits (66), Expect = 0.029 Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 8/93 (8%) Query: 87 SLALFAVLTPLAVAGSPGYIELALAVTVLVGLMQWLVGALRLGSLAHF-ISPSALFGFTS 145 + L ++TPLA A PG L W + L + P+ L TS Sbjct: 8 APVLLWLITPLAFAQLPGITSQPLPGGG----QSWSLPVQTLVFITSLTFIPAILLMMTS 63 Query: 146 GAALLIAVHALKDALGLPAPASHGAGALLIGLA 178 ++I L++ALG P+ + +L+GLA Sbjct: 64 FTRIIIVFGLLRNALGTPSAPPN---QVLLGLA 93
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.005 Identities = 15/77 (19%), Positives = 24/77 (31%), Gaps = 7/77 (9%) Query: 53 QVAAAAVVRYFQTAALHHHEDEEEDLFPALIESMAGSDAVCLHALVDGLVADHARLAALW 112 Q+ A A+ Y ++EE F E + + L+ AA Sbjct: 728 QLFAEALHLYLAGERYFPSPEDEEIYF--RPEQELRLVETGVQGRLWALLTREGAPAAEG 785 Query: 113 AP-----LRQTLEAVAD 124 A + T +AD Sbjct: 786 AAQKGYSVNTTFVTIAD 802
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 32.5 bits (74), Expect = 0.002 Identities = 23/117 (19%), Positives = 45/117 (38%), Gaps = 4/117 (3%) Query: 21 LLDETSGQVIASHAATARIEPASLTKIMTAYVVFGAIHNKELSPDQKVVISTRAWKVPPG 80 +D SG+ + + A R S K++ V + + ++K+ + + Sbjct: 44 EMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQD--LVDY 101 Query: 81 SSKMFLEPGSRVSVDQLLRGLMIQSGNDAAIALAEAVSG--SVEAFVARMNDTAVQL 135 S ++V +L + S N AA L V G + AF+ ++ D +L Sbjct: 102 SPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRL 158
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 35.1 bits (81), Expect = 2e-05 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 8/97 (8%) Query: 56 NKTQLIAYIVEQSGVEAKSVKAVLASLETSVLSSVDKKGAGEFTLPGLFKVAVQKVPAKA 115 NK LIA + E + + K A + ++ ++V S + K + G F+V +A Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVR-----ERA 57 Query: 116 KRFGKDPFTGEERWFPAKPASVKVKVRPLKKLKDAAQ 152 R G++P TGEE AS + K LKDA + Sbjct: 58 ARKGRNPQTGEE---IKIKASKVPAFKAGKALKDAVK 91
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 51.7 bits (124), Expect = 2e-09 Identities = 74/368 (20%), Positives = 132/368 (35%), Gaps = 30/368 (8%) Query: 35 PLLHTISQQFSLSNATAGSIVMIAQLSYALGLILLVPLG----DLFERRGLIVLMTLLSS 90 P+L + + SN ++ L YAL P+ D F RR ++++ ++ Sbjct: 26 PVLPGLLRDLVHSNDVTAHYGILLAL-YALMQFACAPVLGALSDRFGRRPVLLVSLAGAA 84 Query: 91 GGLLLSAFAPNIQMLMLGTAVTGMLSVVAQVLVPFAATLAAPHERGKAVGTVMSGLLLGI 150 + A AP + +L +G V G+ V + A + ER + G + + G+ Sbjct: 85 VDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGM 144 Query: 151 LLARTAAGVLADLGSWRTVYWVAAILMLAMSAALWKVLPRHKSHAAMSYPRLLGSIFRLF 210 + G++ + AA L L +SH P L Sbjct: 145 VAGPVLGGLMGGFSPHAPFFAAAA---LNGLNFLTGCFLLPESHKGERRP-LRREALNPL 200 Query: 211 AEEPLLRGRSLLGGLLFAAFSM-----LWTPLTFLLSGPDYGFNNTTIGL-FGLAGAAGA 264 A RG +++ L+ F M + L + + ++ TTIG+ G + Sbjct: 201 ASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHS 260 Query: 265 YA-ANRFGRLADRGLGNQATRIGLLLLLASWGLMAFGQAS-----VIALLVGILIQDLAI 318 A A G +A R +A +G++ + L+AF ++ LL I A+ Sbjct: 261 LAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPAL 320 Query: 319 QGVHVTNTSSLYRTRPEARSRLTAGYMTSYFIGGATGSLVSSWLYSHY--GWPGVV-TAG 375 Q + E + +L + G L+ + +Y+ W G AG Sbjct: 321 QAMLSRQVDE------ERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAWIAG 374 Query: 376 AVLAAMTL 383 A L + L Sbjct: 375 AALYLLCL 382