>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 30.2 bits (67), Expect = 0.020 Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 6/62 (9%) Query: 82 RSSAPRAAPNAPLAAAASQALSGNSVSS-VSASA-----PAMAVPAPMVAAPVPVHNVAT 135 + A P PL A A S S V+A+A P P P VAAPV + + Sbjct: 178 DAPGTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGS 237 Query: 136 HD 137 H+ Sbjct: 238 HE 239
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 29.9 bits (67), Expect = 0.042 Identities = 16/83 (19%), Positives = 32/83 (38%), Gaps = 7/83 (8%) Query: 552 LQQATKLGIDRTRERIDEALKQARTAAAKQRELFAHAATSDPNELRDELEITVDHLYSFV 611 + + I + ++I+ KQ + + L A + PN L D+ + V L V Sbjct: 153 QDKQVNIAIGASVDQINNYAKQIASLNDQISRLTGVGAGASPNNLLDQRDQLVSELNQIV 212 Query: 612 LGMFDQLGIEVTERSHKERLLRI 634 G+EV+ + + + Sbjct: 213 -------GVEVSVQDGGTYNITM 228
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.9 bits (75), Expect = 0.002 Identities = 11/36 (30%), Positives = 18/36 (50%) Query: 5 EQSVEIKVLARQGHGIKFIARELGISRNTVRKYLRK 40 E + + L A LG++RNT+RK +R+ Sbjct: 437 EYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 30.8 bits (69), Expect = 0.009 Identities = 15/69 (21%), Positives = 27/69 (39%) Query: 73 QCRRDTMLAKAFDAQRLNINTQAGSSNSPHLNALNTLQQRHFKPAAGGLEIPVTSNSLLG 132 + A + + GS ++PH N + T R F P A L I + + + Sbjct: 311 IVEAPELGAAIRVGRGARVTVSGGSLSAPHGNVIETGGARRFAPQAAPLSITLQAGAHAQ 370 Query: 133 GGRQVYQIG 141 G +Y++ Sbjct: 371 GKALLYRVL 379
>cdtoxinb#Cytolethal distending toxin B signature. Length = 269 Score = 28.8 bits (64), Expect = 0.013 Identities = 16/73 (21%), Positives = 22/73 (30%), Gaps = 10/73 (13%) Query: 35 LAFQIYVDENIGRWPLYGSSPLDFRDWLTVARTLVSFAQA----------AVRRHSAAAE 84 A D + W L G+S W R L+S A + + Sbjct: 15 YAQADLTDFRVATWNLQGASATTESKWNINVRQLISGENAVDILAVQEAGSPPSTAVDTG 74 Query: 85 RFFESLGIPLESL 97 S GIP+ L Sbjct: 75 TLIPSPGIPVREL 87
>PF06580#Sensor histidine kinase Length = 349 Score = 186 bits (473), Expect = 4e-58 Identities = 73/307 (23%), Positives = 135/307 (43%), Gaps = 21/307 (6%) Query: 63 LFVQWIVLLSAALLCGLRPWLARLTPGLAGMLSCLLVVGLTLLCTAV------TDVCQLT 116 +F I L+ L R ++ R M +L V + + T + +L Sbjct: 43 IFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQIILRVLPACVVIGMVWFVANTSIWRLL 102 Query: 117 GRISISG-------MVERYLRYSTIALIMSALMLRY-FYLQSQWRKQQQGELR-----AR 163 I+ + + + S L + F+ + + Q ++ A+ Sbjct: 103 AFINTKPVAFTLPLALSIIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQ 162 Query: 164 IESLQARIRPHFLFNTLNSIASLVASDPGKAEQAVLDLSDLFRASLAK-PGSLVTWSEEL 222 + +L+A+I PHF+FN LN+I +L+ DP KA + + LS+L R SL V+ ++EL Sbjct: 163 LMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADEL 222 Query: 223 ALAKRYLSIEQYRLGERLQLDWRVSAIPDDLPIPQLTLQPLLENALIYGIAPRIDGGVVT 282 + YL + + +RLQ + +++ D+ +P + +Q L+EN + +GIA GG + Sbjct: 223 TVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKIL 282 Query: 283 VEADYKGGEFILSVSNPYEEVANRQTSNGTQQALSNIGARIAALFGPHASLSVERRDGRH 342 ++ G L V N +A + T T L N+ R+ L+G A + + + G+ Sbjct: 283 LKGTKDNGTVTLEVENT-GSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKV 341 Query: 343 YTCLRYP 349 + P Sbjct: 342 NAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.7 bits (207), Expect = 1e-20 Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 5/136 (3%) Query: 3 VLIVDDEPLARERLSRMVNEIEGYRVLEDSASNGEEALALIEKHKPDVVLLDIRMPGIDG 62 +L+ DD+ R L++ + GY V SN I D+V+ D+ MP + Sbjct: 6 ILVADDDAAIRTVLNQAL-SRAGYDVR--ITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 63 LQVAAKLCEREAPPAVVFCTAHDEF--ALEAFQVSAVGYLVKPVRAEHLIEALKKAERPN 120 + ++ + V+ +A + F A++A + A YL KP LI + +A Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 121 RVQLAAMTRPAAESGS 136 + + + + + + Sbjct: 123 KRRPSKLEDDSQDGMP 138
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 126 bits (317), Expect = 4e-38 Identities = 71/219 (32%), Positives = 109/219 (49%), Gaps = 5/219 (2%) Query: 11 LLLPLAQAAEAPPD--NDAHDLAYSLGASLGERLHQEVPDLDLKALVDGLKQAYQGKPLA 68 L + A AA D L+YS+GA LG+ + D++ L G++ G L Sbjct: 13 LAMSTAMAATDATSLTTDKDKLSYSIGADLGKNFKNQGIDINPDVLAKGMQDGMSGAQLI 72 Query: 69 LKQERIDQILREHDAAIAQAETAGTDAPTEAALKAERTFMAGEKAKPGVKELADGILMTE 128 L +E++ +L + + +A + E F++ K+KPG+ L G+ Sbjct: 73 LTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPGIVVLPSGLQYKI 132 Query: 129 LTPGTGPKPDANGRVEVRYVGRLPDGKIFD---QSTQPQWFRLDSVISGWTSALQNMPTG 185 + GTG KP + V V Y G L DG +FD ++ +P F++ VI GWT ALQ MP G Sbjct: 133 IDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEALQLMPAG 192 Query: 186 AKWRLVIPSDQAYGAEGAGDLIDPFTPLVFEIELIAVSQ 224 + W + +P+D AYG G I P L+F+I LI+V + Sbjct: 193 STWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVKK 231
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 46.2 bits (109), Expect = 1e-07 Identities = 35/261 (13%), Positives = 63/261 (24%), Gaps = 11/261 (4%) Query: 61 KLQDAATAGKSKAQTKAKDAVAELEELLDALKSRQTETRTYILHLKRDAQESLKLAQGIG 120 +Q + S + A+ A + A S TET + K++++ K Q Sbjct: 1002 NIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVA--ENSKQESKTVEKNEQ--- 1056 Query: 121 RVKEAVG----KILTTRSAKPAAPKAATKAPAAKAPAKAPSKAPAKPPVKAAAAKPVAKA 176 E +S A + A + + + + K + Sbjct: 1057 DATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVET 1116 Query: 177 AAKPAVAAKPAAKPAVVKAPAKTAAKPAARSAAAAKPVAAKSTAAKPAAKPAVTKAPAAA 236 V + K +P A A P A T+ PA Sbjct: 1117 EKTQEVPKVTSQVSP--KQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKE 1174 Query: 237 KAPASSAAKPAAAKPAVAKPAVKAPAKAPVKAVTKPAAVKPAAKPAAAKSATPAPAAAKP 296 + + V+ P + + KP + Sbjct: 1175 TSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNV 1234 Query: 297 TPAAPAAASAKPADNATPTSA 317 PA ++ TS Sbjct: 1235 EPATTSSNDRSTVALCDLTST 1255 Score = 42.7 bits (100), Expect = 1e-06 Identities = 35/181 (19%), Positives = 52/181 (28%), Gaps = 12/181 (6%) Query: 145 KAPAAKAPAKAPSKAPAKPPVKAAAAKPVAKAAAKPAVAAKPAAKPAV---VKAPAKTAA 201 P + P+ P A+ PA A V K +KT Sbjct: 993 DTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVE 1052 Query: 202 KPAARSAAAAKPVAAKSTAAKPAAKPAVTKAPAAAKAPASSAAKPAAAKPAVAK--PAVK 259 K A + A AK AK V + A S ++ + K V+ Sbjct: 1053 K---NEQDATETTAQNREVAK-EAKSNVKANTQTNEV-AQSGSETKETQTTETKETATVE 1107 Query: 260 APAKAPVKAVTKPAAVKPAAK--PAAAKSATPAPAAAKPTPAAPAAASAKPADNATPTSA 317 KA V+ K ++ P +S T P A P +P T+ Sbjct: 1108 KEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTAD 1167 Query: 318 S 318 + Sbjct: 1168 T 1168
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 28.7 bits (64), Expect = 0.039 Identities = 28/169 (16%), Positives = 60/169 (35%), Gaps = 8/169 (4%) Query: 12 ILSFVNFMIFY-SYPFKLEEMGVENGIAGLVVGGATVLTLIMRLVSGVVADRIKTRWAMF 70 S +N M+ S P + V + I V G ++D++ + + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 71 ITTILYC--SSLLLINLNWVPSVILGRLAQGALLGVLSTLLMYYSIAFSDNAAEKSKN-- 126 I+ C S + + ++ +I+ R QGA L+M + + ++++ Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVM---VVVARYIPKENRGKA 140 Query: 127 VSMITFFNVLPTCLAPFIALKITQTWGGGSVALAALMLFLICLFLTFVL 175 +I + + P I I + L ++ + FL +L Sbjct: 141 FGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLL 189
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 75.0 bits (184), Expect = 4e-18 Identities = 49/169 (28%), Positives = 72/169 (42%), Gaps = 2/169 (1%) Query: 89 PEPPPPEPPPPPPPPPPPEPEQPVEDPDAVEPPPKPIEKPKVEKPKPVKKPEPVKKPTPP 148 P +PPP P P PEPE E P + + KPKPVKK E K+ P Sbjct: 61 EPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKP 120 Query: 149 APTPAAAPSPPAPPTPAPAPAAPAAPPAPAKESAAVSGLASLGNPPPEYPGLALRRSWEG 208 + A SP PA ++ A ++ SG +L P+YP A EG Sbjct: 121 VESRPA--SPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEG 178 Query: 209 RVILRIKVLPNGRAGSVEVTKSSGKPALDDAAVEAVRNWKFIPAKRGDT 257 +V ++ V P+GR +V++ + + A+R W++ P K G Sbjct: 179 QVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSG 227
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 26.8 bits (59), Expect = 0.040 Identities = 10/23 (43%), Positives = 14/23 (60%) Query: 1 MKRTTLLVLALTVLSASLAQAAE 23 MKR L ++ +L+A A AAE Sbjct: 1 MKRKVLALVIPALLAAGAAHAAE 23
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 32.3 bits (73), Expect = 0.005 Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 2/78 (2%) Query: 287 DVSTSDLPLMDGRWGDDLFNPETLKLMGVRVGGGVAAGAAA--GAGVDLMVGGVTLGAAA 344 D + + +P + L L G + GG AAG AA GA V L + G A Sbjct: 205 DTNVTAVPASGAPAAVSVLGASELTLDGGHITGGRAAGVAAMQGAVVHLQRATIRRGDAP 264 Query: 345 LVGALAGGALLTARSYGG 362 GA+ GGA+ GG Sbjct: 265 AGGAVPGGAVPGGAVPGG 282
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.4 bits (120), Expect = 4e-10 Identities = 35/183 (19%), Positives = 68/183 (37%), Gaps = 12/183 (6%) Query: 10 RRQQLIQATLTAVDQVGMGDASIALIARLAGVSNGIISHYFQDKNGLIAATMRHLMNALI 69 RQ ++ L Q G+ S+ IA+ AGV+ G I +F+DK+ L + + + Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 70 QNVRERRQALTEDSPRAHLQVIIEGNFDASQVSGPAMKTWLAFWATSMHH----PSLHRL 125 + E + D P + L+ I+ +++ V+ + + + + Sbjct: 72 ELELEYQAKFPGD-PLSVLREILIHVLEST-VTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 126 QRINDHRLYSNLCCQFRRTL------PLEQARNAARGLAALIDGLWLRGALSGDAFDTEQ 179 QR Y + + + R AA + I GL + +FD ++ Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKK 189 Query: 180 AQR 182 R Sbjct: 190 EAR 192
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 33.1 bits (75), Expect = 0.001 Identities = 37/184 (20%), Positives = 67/184 (36%), Gaps = 35/184 (19%) Query: 96 DYSSHLVRGEIGT------PLYREVNNYLRLQHENSGREAEIDNHDEKLSPHIKMLSSAL 149 D+S+ L E+ Y +NNYL ++G ++N + +L + + +AL Sbjct: 271 DWSNKLTPNELADVNDYMRGGYTAINNYLI----SNG---PLNNPNPELDSKVNNIENAL 323 Query: 150 NRLMDVAAFRGTVYRGIRG------------DLDTIARLYHLFD--TGGRYVEPAFMSTT 195 + VYR D + I + + G P F+ST+ Sbjct: 324 KLTPIPSNL--IVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTS 381 Query: 196 RIKDSAQVFEPGTPNNIAFQISLKR---GADISGSSQAPSEEEIMLPMMSEFVIEHASAL 252 + F I +I++ + GA +S E E++L S+F I + Sbjct: 382 IGSVNMSAF---AKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSY 438 Query: 253 SEGK 256 +G Sbjct: 439 KDGT 442
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.0 bits (72), Expect = 0.010 Identities = 36/224 (16%), Positives = 67/224 (29%), Gaps = 9/224 (4%) Query: 18 GREQKYLTYAEVNDHL--PEDISDPE--QVEDIIRMINDMGIPVHESAPDADALMLADAD 73 GR Y E + +I+ P Q + N+ I + AP ++ Sbjct: 976 GRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSE 1035 Query: 74 TDEAAAEEAAAALAAVETDIGRTTDPVRMYMREMGTVELLTREGEIEIAK--RIEEGIRE 131 T E AE + VE + T+ RE+ + + + + +E Sbjct: 1036 TTETVAENSKQESKTVEKNEQDATETTAQ-NREVAKEAKSNVKANTQTNEVAQSGSETKE 1094 Query: 132 VMGAIAHFPGTVD--HILSEYTRVTSEGGRLSDVLSGYIDPDDGIAPPAEVPPPVDPKAV 189 TV+ T T E +++ +S + + + P AE DP Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVN 1154 Query: 190 KAEGADDDEEESADSSDEEDEVESGPDPVIAQQRFGAVSDQMEI 233 E + ++ + PV + +E Sbjct: 1155 IKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVEN 1198
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 31.1 bits (70), Expect = 0.012 Identities = 29/133 (21%), Positives = 50/133 (37%), Gaps = 23/133 (17%) Query: 404 VLSAVMGLSPLGLIVRGLALAAGLLIANWSTVAPYF-----QAVWEAIRGPAMALWDVL- 457 ++ V G+S + G+ + + A + T+ F Q WEA+ + L D++ Sbjct: 56 MVGRVGGVSYTAFLAAGMVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVL 115 Query: 458 --------KAVFAWTPIGMIVANWQPLSEFFAALWDVIKVLATPFSDFLQTLFSWTPLGM 509 KA A IG++ A + ++ L T ++ LGM Sbjct: 116 GEMAWAATKAALAGAGIGVVAAALG-----YTQWLSLLYAL----PVIALTGLAFASLGM 166 Query: 510 VVANWQPISEYFA 522 VV P +YF Sbjct: 167 VVTALAPSYDYFI 179
>PF07132#Harpin protein (HrpN) Length = 356 Score = 36.6 bits (84), Expect = 2e-04 Identities = 18/55 (32%), Positives = 25/55 (45%) Query: 229 NGSSSVSGASTTTGSGSSVGGGSGAGSGGSSGSGSGSSTSISLASSSGSSGGSSD 283 G G+S G +GGG G G G S GSG GS+ L + G+ + + Sbjct: 70 GGGLGGLGSSLGGLGGGLLGGGLGGGLGSSLGSGLGSALGGGLGGALGAGMNAMN 124 Score = 30.0 bits (67), Expect = 0.025 Identities = 22/58 (37%), Positives = 27/58 (46%), Gaps = 2/58 (3%) Query: 226 RRANGSSSVSGASTT-TGSGSSVGGGSGAGSGGSSGSGSGSSTSISLASSSGSSGGSS 282 +R+N + +S TT GS +GGG G G GG GS G L G GSS Sbjct: 43 QRSNIAEQLSDIMTTMMFMGSMMGGGLGGGLGGL-GSSLGGLGGGLLGGGLGGGLGSS 99
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 32.5 bits (74), Expect = 0.001 Identities = 17/64 (26%), Positives = 28/64 (43%), Gaps = 6/64 (9%) Query: 113 WTHRRFSLEVVSCISQALDQLKHRYGNREFELIGYSGGA-----TLALLLAAQRDDVTGV 167 W + +V +D+ + +G ++ LIGYS GA L + A R +V G Sbjct: 91 WKQKDPK-DVTQDTLAIIDKYQAEFGTQKVILIGYSFGAEVIPFVLNEMPARYRKNVLGA 149 Query: 168 QTLA 171 L+ Sbjct: 150 VLLS 153
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 86.6 bits (214), Expect = 2e-21 Identities = 61/255 (23%), Positives = 108/255 (42%), Gaps = 16/255 (6%) Query: 212 LAGRKAVVTGAARGIGASIAETLTRDGAQVILLD-VPQTRKELEALASRLGGQALALNIC 270 + G+ A +TGAA+GIG ++A TL GA + +D P+ +++ + A A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 271 AADAPA-----QLLEHLPDGVDILVHNAGITRDKTLANMPEDFWDSVLAVNLGAPQVLTQ 325 D+ A +E +DILV+ AG+ R + ++ ++ W++ +VN ++ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 326 VLLDGGALKDNARIVLMASISGIAGNRGQTNYTTSKAGLIGFAKAMAPGLKARGISINAV 385 + + + IV + S Y +SKA + F K + L I N V Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 386 APGFIETKMTAHMPFTLREAGRRMSS----------LGQGGTPQDVAEAVAWFSQPGSGA 435 +PG ET M + A + + L + P D+A+AV + +G Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 436 VSGQVLRVCGQNVIG 450 ++ L V G +G Sbjct: 246 ITMHNLCVDGGATLG 260
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 66.8 bits (163), Expect = 4e-14 Identities = 37/151 (24%), Positives = 59/151 (39%), Gaps = 1/151 (0%) Query: 12 LSAFGPLAIDFYLPGFPAMASYFGTDEKHVQLTLAAYFLGLSLGQLAYGPVADRFGRRIP 71 LS F L P +A+ F A+ L S+G YG ++D+ G + Sbjct: 22 LSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRL 81 Query: 72 MLVGVTLFMLASVACAFAPS-LEWLIGARFIQALGGCAGMVLSRAIVSDKCNAVESAKVF 130 +L G+ + SV S LI ARFIQ G A L +V+ K F Sbjct: 82 LLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAF 141 Query: 131 SQLMLVMGLAPILAPMLGGVLVSTFGWQSIF 161 + ++ + + P +GG++ W + Sbjct: 142 GLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL 172
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 32.9 bits (75), Expect = 0.001 Identities = 18/91 (19%), Positives = 33/91 (36%), Gaps = 5/91 (5%) Query: 114 AGITGALKDGKSKLGVDSGLILSFLRHLSEDEAEKTLDQALPFRDAFVAVGLD--SSEMG 171 AG A ++ +GV L ++ L++ + + A + +D S +G Sbjct: 91 AGTIAATENENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYA-IEQKVDIISMSLG 149 Query: 172 HPPS--KFQRVFDRARNEGFLTVAHAGEEGP 200 P + +A L + AG EG Sbjct: 150 GPEDVPELHEAVKKAVASQILVMCAAGNEGD 180
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 71.9 bits (176), Expect = 1e-16 Identities = 57/247 (23%), Positives = 100/247 (40%), Gaps = 26/247 (10%) Query: 41 TPKRVVVLEFSFLDGLASVGVTPVGAADDGDASR--VLPKVRKAVGEWQSVGLRSQPNIE 98 P R+V LE+ ++ L ++G+ P G AD + P + +V + VGLR++PN+E Sbjct: 34 DPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVID---VGLRTEPNLE 90 Query: 99 VIARLKPDLIIADLGRHQALYNDLASLAPTLMLPSRGEDYQGSLKSAGLIGMA--LGKGP 156 ++ +KP ++ G + LA +AP ++ L MA L Sbjct: 91 LLTEMKPSFMVWSAG-YGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQS 149 Query: 157 EMQARIAENRQHLKTVAEQIPADSN---VLFGVAREDSFSVHGPHSYAGSVLQAIGLQVP 213 + +A+ ++++ + +L + V GP+S +L G+ Sbjct: 150 AAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIP-- 207 Query: 214 EVRNNAAPTEF-------VSLEQLLAL-DPNWLLVGHYRRPSIVDTWSKQPLWQVLGAVR 265 NA E VS+++L A D + L H +D PLWQ + VR Sbjct: 208 ----NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH-DNSKDMDALMATPLWQAMPFVR 262 Query: 266 NKQVAEV 272 + V Sbjct: 263 AGRFQRV 269
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 46.6 bits (110), Expect = 2e-08 Identities = 43/193 (22%), Positives = 78/193 (40%), Gaps = 17/193 (8%) Query: 18 KTALIIGASRGLGLGLVQRLTEQGWQVTATVRDPQNAENLRAVDGVRIET-----VDMDD 72 K A I GA++G+G + + L QG + A +P+ E + + D+ D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 73 TASLEVLVQKLRGEV--FDVLFVNAGI--TGPKHQSAAQSTAAELGQLFLTNAVAPIRLA 128 +A+++ + ++ E+ D+L AG+ G H + + E F N+ + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDE----EWEATFSVNSTGVFNAS 124 Query: 129 ERFIGQIRP-GTGVLAFMSSWLGSVACPDGAELALYKASKAALNSMTNTFVSQLGENRPT 187 + +G + + S + A +A Y +SKAA T +L E Sbjct: 125 RSVSKYMMDRRSGSIVTVGS---NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 188 VLSMHPGWVKTDM 200 + PG +TDM Sbjct: 182 CNIVSPGSTETDM 194
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 28.3 bits (63), Expect = 0.041 Identities = 9/15 (60%), Positives = 11/15 (73%), Gaps = 1/15 (6%) Query: 125 IPFLSDIPLIGRMLF 139 +P L DIP+IG LF Sbjct: 560 VPLLGDIPVIGA-LF 573
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 99.5 bits (248), Expect = 4e-26 Identities = 44/136 (32%), Positives = 72/136 (52%), Gaps = 1/136 (0%) Query: 9 PAPRVLVVDDHRKIRDPLAVYLRRHLFDVRTAEDAAGMWQLLRQQPFDVVVLDVMLPDGD 68 +LV DD IR L L R +DVR +AA +W+ + D+VV DV++PD + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 69 GFELCSRLH-RRENIPVILLTARDTSADRVRGLDIGADDYLTKPFEPRELVARINSVLRR 127 F+L R+ R ++PV++++A++T ++ + GA DYL KPF+ EL+ I L Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 128 RGPVPTVMEATPAEAA 143 P+ +E + Sbjct: 122 PKRRPSKLEDDSQDGM 137
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 40.2 bits (94), Expect = 3e-05 Identities = 49/244 (20%), Positives = 89/244 (36%), Gaps = 44/244 (18%) Query: 570 VIGQEEAVVAVSNAVRRSRAGLSDPNRPSGSFMFLGPTGVGKTELCKALAEFLFDTEEAM 629 ++G+ A+ + + R +D + M G +G GK + +AL ++ Sbjct: 139 LVGRSAAMQEIYRVLAR--LMQTD-----LTLMITGESGTGKELVARALHDYGKRRNGPF 191 Query: 630 VRIDMSEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSV-------ILLDEVEKA 682 V I+M+ + L G+E+G + T A R + LDE+ Sbjct: 192 VAINMAAIPRDLIESEL-------FGHEKGAF-TGAQTRSTGRFEQAEGGTLFLDEIGDM 243 Query: 683 HSDVFNILLQVLEDG---RLTDSHGRTVDFRNTVIVMTSNLGSAQIQELVGDREAQRAAV 739 D LL+VL+ G + D R IV +N +++ + Sbjct: 244 PMDAQTRLLRVLQQGEYTTVGGRTPIRSDVR---IVAATN---KDLKQSINQ-------- 289 Query: 740 MDAVSTHFRPEFVNRIDEVVIFEPLARDQIAGITDIQLGRLRKRLAERELTMVLSPEALD 799 FR + R++ V + P RD+ I D+ +++ E EAL+ Sbjct: 290 -----GLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALE 344 Query: 800 KLIA 803 + A Sbjct: 345 LMKA 348 Score = 35.2 bits (81), Expect = 0.001 Identities = 43/179 (24%), Positives = 66/179 (36%), Gaps = 34/179 (18%) Query: 151 DPNIEESRQALDKYTVDLTKRAEEG-KLDPVIGRDDEIRRTIQVLQRRTKNN-PVLI-GE 207 I +AL + +K ++ P++GR ++ +VL R + + ++I GE Sbjct: 109 TELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGE 168 Query: 208 PGVGKTAIAEGLAQR----------IINGEVPDGLRGKRLLSLDMGALI-AGAKYRGEFE 256 G GK +A L I +P L L + GA A + G FE Sbjct: 169 SGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFE 228 Query: 257 ERLKSLLNELSKQEGQIILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATT 315 + LF+DE+ G+ MDA L L +GE VG T Sbjct: 229 QAEGGT------------LFLDEI--------GDMPMDAQTRLLRVLQQGEYTTVGGRT 267
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 33.6 bits (77), Expect = 0.001 Identities = 61/348 (17%), Positives = 102/348 (29%), Gaps = 28/348 (8%) Query: 29 LPVYLTSFSDTFGGASGLTAEQLGRIPAVMFLSFIVAILVTGPLADRGSAMAFILIGLLI 88 LP L S G + A+ L V G L+DR +L+ L Sbjct: 28 LPGLLRDL-----VHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAG 82 Query: 89 TMAGLGVVACSPSYSFLLFAVAVMGFGAGVLDMILSPIVAALQPDRRSAAINWLHAFFCV 148 ++A +P L V G + + I D R+ ++ A F Sbjct: 83 AAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGF 142 Query: 149 GAVGAVLIASVALRWGISWRIVSLVMMAAPLFTFLL---FLRLTLPPLIDEDTQRDSMPA 205 G V ++ + G S A FL L + + P Sbjct: 143 GMVAGPVLGGLM--GGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPL 200 Query: 206 L---------IRQPFFIVCLIAIFLGGATETGLSQWLPTYVEQGLGYSKEAGGFTLAGFS 256 + V I +G + E + G +LA F Sbjct: 201 ASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVI----FGEDRFHWDATTIGISLAAFG 256 Query: 257 VGMALGR-MVAAVLQEHIPPVPLMLGCCAVTAVLFILISFPPSPVIAIAAAI--AAGFSG 313 + +L + M+ + + ++ +IL++F +A + A+G G Sbjct: 257 ILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIG 316 Query: 314 SCLWPTMLAVSADAYPQGGATMFSVLTAIGNAGCSIVPWLVGVIINYS 361 ML+ D QG L A+ + + P L I S Sbjct: 317 MPALQAMLSRQVDEERQGQLQ--GSLAALTSLTSIVGPLLFTAIYAAS 362
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 29.0 bits (64), Expect = 0.050 Identities = 32/145 (22%), Positives = 59/145 (40%), Gaps = 7/145 (4%) Query: 36 NAPAPKLTAEQAKALGVEGDTPSDTLRTVVAEGRELKQQITDVMA--QNSAVKQDNEALK 93 +AP PK EQ KAL E + + + + K++ A +N N Sbjct: 134 DAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANLENLTNAMSNPQNL 193 Query: 94 QRLANIDQTVEQRLKNAQEQFKLDSQQQQQSVLDGLRKQMDELTRMGQNGATHPDLPIGL 153 N+ + ++Q+ +N +Q + Q+Q+ + L KQ++EL + A + Sbjct: 194 SNNKNLSELIKQQRENELDQMERLEDMQEQAQANAL-KQIEELNKKQAEEAVRQRAKDKI 252 Query: 154 GVQQGDGQQFKSDS----SGSDLMW 174 ++ Q+ D+ S SD W Sbjct: 253 SIKTDKSQKSPEDNSIELSPSDSAW 277
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.4 bits (92), Expect = 2e-05 Identities = 58/302 (19%), Positives = 105/302 (34%), Gaps = 31/302 (10%) Query: 1 MIFSGQTLSPIGSGLTQFVLLWWITDTTGSLAALATAGV-VAL--LPQALISPLGGIFAD 57 +I S L +G GL VL + D S A G+ +AL L Q +P+ G +D Sbjct: 9 VILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSD 68 Query: 58 RYSRRVLMIATDMISALCMSILIVLFLTERVELWHIYWMMF---VRSAMQAFQTPAASAS 114 R+ RR +++ + +A+ +I+ W+++ + + + A A Sbjct: 69 RFGRRPVLLVSLAGAAVDYAIMATA---------PFLWVLYIGRIVAGITGATGAVAGAY 119 Query: 115 VAMLVPRSFLPRAAGLSQAMQGISLVAAAPLGALAISM---IPLGWALSIDVVTALLGCL 171 +A + R G A G +VA LG L P A +++ + L GC Sbjct: 120 IADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCF 179 Query: 172 PLLRYRIPQASNSNRTGLSTLRSEFRDGLHLIWSHPGLRRLYALMGAVVLVIMPSFTLVP 231 L P++ R L + L A+ + LV L Sbjct: 180 LL-----PESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWV 234 Query: 232 LLVKEHFGGGAPHVAFIDAMAGAGMLVGGVVVALFAPRQPVTW-----ILWGFATSCFAL 286 + ++ F A + ++A G ++ + A+ ++ G Sbjct: 235 IFGEDRFHWDATTIGI--SLAAFG-ILHSLAQAMITGPVAARLGERRALMLGMIADGTGY 291 Query: 287 AL 288 L Sbjct: 292 IL 293
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 44.4 bits (105), Expect = 8e-07 Identities = 17/83 (20%), Positives = 33/83 (39%), Gaps = 7/83 (8%) Query: 424 RVLLIEDNYNVLQATAMLLRKWGCDVQTASATPEA-----SVDCDLVVTDFDLDRSATGA 478 +L+ +D+ + L + G DV+ S + D DLVVTD + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPD-ENAF 63 Query: 479 DCIRYLSELHGRRIPAIVITGHA 501 D + + + +P +V++ Sbjct: 64 DLLPRIKKARP-DLPVLVMSAQN 85
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 56.4 bits (136), Expect = 1e-11 Identities = 22/114 (19%), Positives = 46/114 (40%), Gaps = 3/114 (2%) Query: 4 RIIVADDHPLFREGMLRTIERLLPEAVIEQAGNLNEVLMLARSGDEVDTLILDLRFPGLN 63 I+VADD R + + + R + + N + +G + D ++ D+ P N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYD--VRITSNAATLWRWIAAG-DGDLVVTDVVMPDEN 61 Query: 64 SMQTIAELRNEFRRTSIIVVSMVDDPETIAQVMSNGADGFIGKNIDPQEITESI 117 + + ++ ++V+S + T + GA ++ K D E+ I Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 46.4 bits (110), Expect = 2e-07 Identities = 27/124 (21%), Positives = 51/124 (41%), Gaps = 11/124 (8%) Query: 420 RICLVEDDNNVLMATAALLERWGCEVQTARSAQGLITDC-----DIIVADYDLGTAANGL 474 I + +DD + L R G +V+ +A L D++V D + N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPD-ENAF 63 Query: 475 DCIESIRAARGWDVPALIVTGR-EVEVVLESLQGAEVSVLSKPLRPSE---LRLNLLSVR 530 D + I+ AR D+P L+++ + +++ + L KP +E + L+ Sbjct: 64 DLLPRIKKARP-DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 531 ERRV 534 +RR Sbjct: 123 KRRP 126
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 343 bits (881), Expect = e-121 Identities = 158/283 (55%), Positives = 200/283 (70%), Gaps = 1/283 (0%) Query: 3 LLDLLASSPLAFVTTCCLLGLIVGSFLNVVVYRLPKMMERDWKVQSREMLGLPAE-PDQP 61 LL+L P + + L L++GSFLNVV++RLP M+ER+W+ + R E D+P Sbjct: 4 LLELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDEP 63 Query: 62 VFNLILPHSSCPHCAHKIRPWENLPVISYLLLRGKCSQCKAPISKRYPVVELTCAVLSAY 121 +NL++P S CPHC H I EN+P++S+L LRG+C C+APIS RYP+VEL A+LS Sbjct: 64 PYNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSVA 123 Query: 122 VAWHFGFGWQAAAMLVLSWGLLAMSLIDADHQLLPDSLVLPLLWLGLIVNAFGLFTSLSD 181 VA GW A L+L+W L+A++ ID D LLPD L LPLLW GL+ N G F SL D Sbjct: 124 VAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGD 183 Query: 182 ALWGAVAGYLTLWSVFWLFKLVTGKEGMGYGDFKLLAMLGAWGGWQILPLTILLSSLVGA 241 A+ GA+AGYL LWS++W FKL+TGKEGMGYGDFKLLA LGAW GWQ LP+ +LLSSLVGA Sbjct: 184 AVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGA 243 Query: 242 VLGVIMMRVRRVESGTPIPFGPYLAIAGWIALLWGGQITDSYM 284 +G+ ++ +R PIPFGPYLAIAGWIALLWG IT Y+ Sbjct: 244 FMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLWGDSITRWYL 286
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 431 bits (1110), Expect = e-152 Identities = 114/404 (28%), Positives = 220/404 (54%), Gaps = 10/404 (2%) Query: 11 YTWEGVDKKGTKTSGELSGHNLALVKAQLRKQGINPTKVRKKSVSI---------FGKGK 61 Y ++ +D +G K G + + LR++G+ P V + + Sbjct: 4 YHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRKI 63 Query: 62 KIKPLDIAFFSRQMATMMKAGVPLLQSFDIISEGAENPNMRTLVDSLKQEVSAGNSFATA 121 ++ D+A +RQ+AT++ A +PL ++ D +++ +E P++ L+ +++ +V G+S A A Sbjct: 64 RLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLADA 123 Query: 122 LRRKPEYFDELFCNLVDAGEQAGALESLLDRVASYKEKTEKLKAKIKKAMTYPAAVLIVA 181 ++ P F+ L+C +V AGE +G L+++L+R+A Y E+ ++++++I++AM YP + +VA Sbjct: 124 MKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVVA 183 Query: 182 VIVSGILLIKVVPQFQSIFASFGADLPAFTLMVIGLSDIVQKWWLIIVIAFFATIFMLKR 241 + V ILL VVP+ F LP T +++G+SD V+ + +++A A + Sbjct: 184 IAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFRV 243 Query: 242 AYKKSQNFRDALDRFLLKLPIIGPLIFKSSVARYARTLATTFAAGVPLVEALDSVAGATG 301 ++ R + R LL LP+IG + + ARYARTL+ A+ VPL++A+ Sbjct: 244 MLRQE-KRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMS 302 Query: 302 NVVFKNAVNRVKQDVSTGMQLNFSMRSTGVFPSLAIQMTSIGEESGALDAMLDKVATYYE 361 N ++ ++ V G+ L+ ++ T +FP + M + GE SG LD+ML++ A + Sbjct: 303 NDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQD 362 Query: 362 EEVDNMVDNLTSLMEPMIMAILGVIVGGLVIAMYLPIFKLGNVV 405 E + + L EP+++ + +V +V+A+ PI +L ++ Sbjct: 363 REFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 50.3 bits (120), Expect = 8e-11 Identities = 16/53 (30%), Positives = 37/53 (69%) Query: 1 MNAQKGFTLIELMIVVAIVGILAAVAIPSYQNYAKKAAYTEVLAAMASVKTAV 53 + Q+GFTL+E+M+V+ I+G+LA++ +P+ +KA + ++ + +++ A+ Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENAL 56
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 33.1 bits (75), Expect = 0.002 Identities = 13/53 (24%), Positives = 16/53 (30%), Gaps = 3/53 (5%) Query: 156 EPLAKNFGVEVSAPQDQPAPAPAPAPAPAPAPAPVPAPAAKPTVNLSKITLDK 208 E LAK + D P P P P KP N + + K Sbjct: 453 EELAK---LRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETK 502 Score = 29.6 bits (66), Expect = 0.025 Identities = 12/62 (19%), Positives = 19/62 (30%), Gaps = 8/62 (12%) Query: 156 EPLAKNFGVEVSAPQDQPAPAPAPAPAPAPAPAPVPAPAAKPTVNLSKITLDKTRASISL 215 E LAK ++ A A + + P P A P + K + + Sbjct: 446 EKLAK--------QAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAP 497 Query: 216 EK 217 K Sbjct: 498 MK 499
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 610 bits (1575), Expect = 0.0 Identities = 226/563 (40%), Positives = 347/563 (61%), Gaps = 13/563 (2%) Query: 404 LSAVPASPGIAIGPAHVQVLQTFD-YPQKGESVAAERERLQTAIGEVRRDIENLIQRSK- 461 ++ + AS G+AI A + + D V+ E E+L A+ + + ++ + +++ Sbjct: 5 ITGIAASSGVAIAKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTEA 64 Query: 462 --SKAIREIFITHQEMLDDPELIREVEQRL-NDNESAAAAWATVIEAAAVQQEQLKDALL 518 EIF H +LDDPEL+ ++ ++ N+ +A A V + E + + + Sbjct: 65 SMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEYM 124 Query: 519 AERAADLRDVGRRVLAQICGVET--VAAPDEPYILVMDEVGPSDVARLDPAQVAGILTAR 576 ERAAD+RDV +RVL + GVET +A E +++ +++ PSD A+L+ V G T Sbjct: 125 KERAADIRDVSKRVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATDI 184 Query: 577 GGATAHSAIVARALGIPALVGAGDEVLLLKPGTVLLLDSQRGRLTVAPDQATLQRAVEDR 636 GG T+HSAI++R+L IPA+VG + ++ G ++++D G + V P + ++ E R Sbjct: 185 GGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEEKR 244 Query: 637 DAREQRLKAAAAARMEPAVTRDGHAVEVFANIGDSTGTPAAVEQGAEGVGLLRTELLFMA 696 A E++ + A EP+ T+DG VE+ ANIG + G EG+GL RTE L+M Sbjct: 245 AAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLYMD 304 Query: 697 HSQAPDEATQEAEYRRVLTDLGGRPLVVRTLDVGGDKPLPYWPIAKEENPFLGVRGIRLT 756 Q P E Q Y+ V+ + G+P+V+RTLD+GGDK L Y + KE NPFLG R IRL Sbjct: 305 RDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFRAIRLC 364 Query: 757 LQRPDVMESQLRALLRAADSGPLRIMFPMIGTLEEWREARAMTERLRAE-----IPVSD- 810 L++ D+ +QLRALLRA+ G L++MFPMI TLEE R+A+A+ + + + + VSD Sbjct: 365 LEKQDIFRTQLRALLRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVSDS 424 Query: 811 LQLGIMIEVPSAALIAPVLAREVDFFSIGTNDLTQYTMAIDRGHPTLSAQADGLHPSVLQ 870 +++GIM+E+PS A+ A + A+EVDFFSIGTNDL QYTMA DR + +S HP++L+ Sbjct: 425 IEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPAILR 484 Query: 871 LIDMTVRAAHANGKWVGVCGELAADPLAVPVLVGLGVDELSVSARSIGEVKACVRELTLS 930 L+DM ++AAH+ GKWVG+CGE+A D +A+P+L+GLG+DE S+SA SI ++ + +L+ Sbjct: 485 LVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLKLSKE 544 Query: 931 SAQQLAQKALTAGSAAEVRALVE 953 + AQKAL +A EV LV+ Sbjct: 545 ELKPFAQKALMLDTAEEVEQLVK 567
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 38.8 bits (90), Expect = 7e-06 Identities = 15/56 (26%), Positives = 27/56 (48%) Query: 90 NAWDNEDFVKAIKATGREQLIIAGVVTDVCVTFPTLSALAEGFEVFVVTDASGTFN 145 +A+ + ++ ++ GR+QLII G+ + A E + F V DA F+ Sbjct: 127 SAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFS 182
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 57.7 bits (139), Expect = 4e-12 Identities = 51/178 (28%), Positives = 67/178 (37%), Gaps = 15/178 (8%) Query: 57 PLAQPEPPPVQPEEPPPAPPVIDSEEAEPAPPPPPPKPVSKPEPKPEPKPAPKPEPRPKP 116 P P VQP P P E EP P PP PV +PKP+PKP PKP + + Sbjct: 52 PADLEPPQAVQPPPEPVVEP---EPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQE 108 Query: 117 LPKPAVAKPVEPVQAASKPIASAPVSPPSPPSPPAPPAPPKVDTQGIEGGYLKGLRNDLD 176 PK V + + +AP S + A P G Sbjct: 109 QPKRDVKPVESRPASPFE--NTAPARLTSSTATAATSKPVTSVASGPRALSR-------- 158 Query: 177 GYKQYPTGRQASLERPSGEVVVWLLVDRQGRVLDSGIQTQASSMLLNRAATNSLRRIK 234 QYP QA R G+V V V GRV + I + + + R N++RR + Sbjct: 159 NQPQYPARAQAL--RIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWR 214
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 34.7 bits (79), Expect = 0.004 Identities = 47/161 (29%), Positives = 66/161 (40%), Gaps = 23/161 (14%) Query: 747 ALEELEAENLAVQDKHRQALEKLEAEHL-ASQENHRSVLEQFEAVHLASQESYRLALEER 805 A E +A+ A +D Q L+ + E L + S E A + A Q E Sbjct: 75 AAAEAQAKAKANRDALTQRLKDIVNEALRHNASRTPSATELAHANNAAMQA-------ED 127 Query: 806 EAANLAAQESHRLALQEREAANLAIQESHRTATESLKAENLRVQADHLRVLADIDAATLD 865 E LA E A +E EAA A QE+ E + E R +A+ R L + Sbjct: 128 ERLRLAKAEEK--ARKEAEAAEKAFQEA-----EQRRKEIEREKAETERQL-----KLAE 175 Query: 866 AQEKHRAKLAELEIAILAAQESHRLA---LVDKDTHVHNLN 903 A+EK A L+E A+ AQ+ A +V D + LN Sbjct: 176 AEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLN 216
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 29.5 bits (66), Expect = 0.011 Identities = 20/65 (30%), Positives = 35/65 (53%) Query: 192 TVLTTVLLFLSPVLYPVAALPEVYRPWLQMNPLTYIIEESRSVLLFGNLPHWDSLGIAIA 251 T++ T +LFLS ++PV LP V++ + PL++ I+ R ++L + A+ Sbjct: 183 TLVITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALC 242 Query: 252 IGAVI 256 I VI Sbjct: 243 IYIVI 247
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 48.6 bits (116), Expect = 1e-08 Identities = 34/164 (20%), Positives = 59/164 (35%), Gaps = 24/164 (14%) Query: 1 MKILLLGKNGQVGWELQRSLAVLG-EVVALDRHTASTVYGDLS----------------- 42 MK L+ G G +G+ + + L G +VV +D Y D+S Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLND---YYDVSLKQARLELLAQPGFQFH 57 Query: 43 -GDLSSLDGLRNTIRCVKPQVIVNAAAYTAVDKAETEQELAHTVNALASQVLAEEARQLD 101 DL+ +G+ + + + + AV + N + E R Sbjct: 58 KIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK 117 Query: 102 -ALLVHYSTDYVFDGTGTSAWKESDAVS-PVNYYGATKLEGEQL 143 L++ S+ V+ + D+V PV+ Y ATK E + Sbjct: 118 IQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELM 161
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 182 bits (464), Expect = 5e-57 Identities = 81/353 (22%), Positives = 141/353 (39%), Gaps = 44/353 (12%) Query: 1 MKILVTGGAGFIGSAVIRHIIANTTDSVVNVDKLT--YAGNL-ESLQSADQSERYAFEHV 57 MK LVTG AGFIG V + ++ VV +D L Y +L ++ + F + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DICNREDLDRVFKEHQPDAVMHLAAESHVDRSITGPSEFIQTNIIGTYVLLEAARSYWNT 117 D+ +RE + +F + V V S+ P + +N+ G +LE R Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN--- 116 Query: 118 LDEVRKANFRFHHISTDEVYGDLEGPEDLFTETTPY-QPSSPYSASKASSDHLVRAWSRT 176 +++ + S+ VYG + F+ P S Y+A+K +++ + +S Sbjct: 117 --KIQ----HLLYASSSSVYGL--NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHL 168 Query: 177 YGLPTLVTNCSNNYGPCHFPEKLIPLIILNALEGKPLPIYGKGDQVRDWLYVEDHARALY 236 YGLP YGP P+ + LEGK + +Y G RD+ Y++D A A+ Sbjct: 169 YGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAII 228 Query: 237 KVV------------------TEGEIGETYNIGGHNEKQNLEVVNTVCALLDQLRPDSAH 278 ++ YNIG + + ++ + + L A Sbjct: 229 RLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGI----EAK 284 Query: 279 RPHANLITYVQDRPGHDLRYAIDASKIQRELGWVPEESFESGIRKTVQWYLDN 331 + + +PG L + D + +G+ PE + + G++ V WY D Sbjct: 285 K------NMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 26.1 bits (57), Expect = 0.047 Identities = 10/20 (50%), Positives = 12/20 (60%) Query: 8 SWVAAGDWSEAVEPYPPGAA 27 +W+ GDW E V P GAA Sbjct: 52 AWIKPGDWLEHVSPALAGAA 71
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 27.5 bits (61), Expect = 0.049 Identities = 19/88 (21%), Positives = 35/88 (39%), Gaps = 2/88 (2%) Query: 132 IALMVFSFARIGAALAMKVEDVYIQNQRLWVRLKEKGGKQHVMPCQHSLEAYLHAYLVET 191 I+ M+F + I + + +Y + + ++ G + Q E YLV Sbjct: 119 ISSMLF-LSMINYSKDKGYDGIYTIVSHPMLTILKRSGWGIRVVEQGLSEKEERVYLVFL 177 Query: 192 GIDNDPKGPLFRTIGRGTEQLSVNALPQ 219 +D++ + L R I R + N L Q Sbjct: 178 PVDDENQEALARRINR-SGTFMSNELKQ 204
>cloacin#Cloacin signature. Length = 551 Score = 33.1 bits (75), Expect = 0.005 Identities = 25/102 (24%), Positives = 38/102 (37%), Gaps = 13/102 (12%) Query: 730 GSTQATSEMRSNTEKFGPSSLGNGSSGGGKK--PIRGGGTSGLQHKVGDGDGDGGGRSGQ 787 G+ + + G + SG + P GG SG+ G G G+GGG Sbjct: 12 GAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNS 71 Query: 788 SGASKLLSSGPQGVAPSGAADDGPIGFGGGSFASETSPKTSG 829 G S G + +A P+ FG F + ++P G Sbjct: 72 GGGS--------GTGGNLSAVAAPVAFG---FPALSTPGAGG 102 Score = 31.6 bits (71), Expect = 0.015 Identities = 22/70 (31%), Positives = 25/70 (35%), Gaps = 11/70 (15%) Query: 775 GDGDGDGGGRSGQSGASKLLSSGPQGVAPSGAADDG--------PIGFGGGSFASETSPK 826 GDG G G SG ++ GP G+ G A DG P G G GS Sbjct: 4 GDGRGHNTGAHSTSGN---INGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGS 60 Query: 827 TSGRDGNVNN 836 G G N Sbjct: 61 GHGNGGGNGN 70
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 49.8 bits (119), Expect = 5e-09 Identities = 36/232 (15%), Positives = 78/232 (33%), Gaps = 33/232 (14%) Query: 61 DNQWVKRGDLLMQIDPEHYRIAVKQAQALLASRKATWEMRKLNARRRADMDELVISAENR 120 Q + + +L Q E+ + + S+ E L+A+ + ++ + Sbjct: 245 HKQAIAKHAVLEQ---ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQL----VTQLFK 297 Query: 121 DDASNVATSALADYQLAQAQLEAAELNLARTRVLAAVDGYVTNLNVHR-GDYARIGEAKM 179 ++ + + L +L E + + A V V L VH G E M Sbjct: 298 NEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLM 357 Query: 180 AVV-DMNSFWVYGFFEETKLPHLKVGDPADLQLMS-----GEVLKGHVESIARGIYDRDN 233 +V + ++ V + + + VG A +++ + L G V++I + Sbjct: 358 VIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQR 417 Query: 234 PQSRELIADVNPTFNWVRLAQRVPVRIHLDQVPQD---VLLAAGMTCTVIVR 282 L V + I + + + L++GM T ++ Sbjct: 418 LG----------------LVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIK 453 Score = 46.7 bits (111), Expect = 4e-08 Identities = 17/138 (12%), Positives = 48/138 (34%), Gaps = 8/138 (5%) Query: 46 VAADVSGSVVDVPVHDNQWVKRGDLLMQIDPEHYRIAVKQAQALLASRKATWEMRKLNAR 105 + + V ++ V + + V++GD+L+++ + Q+ L + + R Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLE-QTRYQILS 157 Query: 106 RRADMDELVISAENRDDAS-------NVATSALADYQLAQAQLEAAELNLARTRVLAAVD 158 R ++++L + + ++L Q + Q + + L + A Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERL 217 Query: 159 GYVTNLNVHRGDYARIGE 176 + +N + Sbjct: 218 TVLARINRYENLSRVEKS 235
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 76.6 bits (188), Expect = 1e-18 Identities = 51/180 (28%), Positives = 82/180 (45%), Gaps = 9/180 (5%) Query: 3 IALITGCSSGIGRALADAFKATGYEVWA----TARKADDVAALSAAGFIAVQ--LDVNDK 56 IA ITG + GIG A+A + G + A + V++L A A DV D Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 57 LALEQLAAGL--EHSGLDVLINNAGYGAMGPLLDGGVDALQRQFETNVFSVVGVTRALFP 114 A++++ A + E +D+L+N AG G + + + F N V +R++ Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 115 ALR-RNKGLVVNIGSVSGVLVTPFAGAYCASKAAVHALSDALRLELAPFGVQVMEVQPGA 173 + R G +V +GS + AY +SKAA + L LELA + ++ V PG+ Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 1e-05 Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 10/82 (12%) Query: 67 CFLALRDDAVVGVI---TCWTS-AFIKDLVVHPDARAGGIGFALLNHLFSQLRGPVTRPR 122 FL ++ +G I + W A I+D+ V D R G+G ALL+ + Sbjct: 67 AFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLH-----KAIEWAKEN 121 Query: 123 EAA-VDLHVMENNLTARRLYEK 143 + L + N++A Y K Sbjct: 122 HFCGLMLETQDINISACHFYAK 143
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 56.4 bits (136), Expect = 5e-11 Identities = 24/111 (21%), Positives = 46/111 (41%), Gaps = 7/111 (6%) Query: 182 LSKARILVVDDSQVALQQSIITLRNLGIECHTARSAREAIDVLLDLQGTARQINVVVSDI 241 ++ A ILV DD L G + +A + A ++VV+D+ Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWI-----AAGDGDLVVTDV 55 Query: 242 EMSEMDGYALTRTLRDTPDFSDLYILLHTSLDSAMNSEKSQIAGANAVLTK 292 M + + + L ++ DL +L+ ++ ++ M + K+ GA L K Sbjct: 56 VMPDENAFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPK 104
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 66.2 bits (161), Expect = 4e-15 Identities = 41/203 (20%), Positives = 75/203 (36%), Gaps = 21/203 (10%) Query: 11 FTFEPSRTAVVIIDMQRDFLEPGGFGAALGNDVAPLQAIVPTVQQLLALAREQGLVVIHT 70 + +P+R ++I DMQ F++ +P+ + +++L + G+ V++T Sbjct: 24 WVPDPNRAVLLIHDMQNYFVDA------FTAGASPVTELSANIRKLKNQCVQLGIPVVYT 77 Query: 71 RESHLPDLSDCPQAKL-DHGLPGLRIGDPGPMGRILVRGEPGNQIIDALTPLASEWVIDK 129 + + +A L D PGL G +II L P + V+ K Sbjct: 78 AQP--GSQNPDDRALLTDFWGPGLN------------SGPYEEKIITELAPEDDDLVLTK 123 Query: 130 PGKGMFFATDLQQRLTVAGITHLIFAGVTTEVCVQTSMREACDLGYRCLLIEDATESYFA 189 F T+L + + G LI G+ + + EA + + DA + Sbjct: 124 WRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSL 183 Query: 190 AFKQATLDMITAQGAIVGRVASL 212 Q L+ + A SL Sbjct: 184 EKHQMALEYAAGRCAFTVMTDSL 206
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 50.0 bits (119), Expect = 2e-09 Identities = 46/207 (22%), Positives = 73/207 (35%), Gaps = 29/207 (14%) Query: 9 APYPWPWNGQLHAHNT---------ALIVIDMQTDFCGVGGYVDSMGYDLALTRAPIEPI 59 PY P + + L++ DMQ F VD+ + I Sbjct: 7 QPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYF------VDAFTAGASPVTELSANI 60 Query: 60 RALLAVMRPLGFTIIHTREGHRPDLSDLPANKRWRSQRIGAGIGDPGPCGKILVRGEPGW 119 R L LG +++T + P ++ + + PG L G Sbjct: 61 RKLKNQCVQLGIPVVYTAQ---------PGSQNPDDRALLTDFWGPG-----LNSGPYEE 106 Query: 120 EIIDELAPLPGEIIIDKPGKGSFCATDLELILRTRGIDNLILTGITTDVCVHTTMREAND 179 +II ELAP ++++ K +F T+L ++R G D LI+TGI + T EA Sbjct: 107 KIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFM 166 Query: 180 RGFECLLLEDCCGATDPANHAAALSMV 206 + + D H AL Sbjct: 167 EDIKAFFVGDAVADFSLEKHQMALEYA 193
>PF06917#Periplasmic pectate lyase Length = 555 Score = 30.3 bits (68), Expect = 0.012 Identities = 19/86 (22%), Positives = 34/86 (39%), Gaps = 6/86 (6%) Query: 4 GLGGLNKSPNGVVIGLAQLALPDPHTREAL--WAQTQKVVGMVAKARRSNPGMDLIVFPE 61 L LNK+ + AQ + P+ AL A+ + + A + + +F Sbjct: 424 QLAELNKTQRRATLMAAQRPIASPYLLLALVELAEHCQCPTLFTLAWQ----IGDDLFKR 479 Query: 62 YSLHGLSMSTAPEIMCSLDGPEVVAL 87 + GL + +A +D P +AL Sbjct: 480 HYHRGLFVESAQHRYFRIDNPIALAL 505
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.4 bits (79), Expect = 8e-04 Identities = 48/194 (24%), Positives = 71/194 (36%), Gaps = 13/194 (6%) Query: 20 PNRLIFISVLVATMGALAFGYDTGIIAGALPFMTLPADQGGLGLNAYSEGMITASLIVGA 79 PNR + + + + A+ G +I LP + D G++ A + Sbjct: 3 PNRPLIVILSTVALDAVGIG----LIMPVLPGLL--RDLVHSNDVTAHYGILLALYALMQ 56 Query: 80 AFGSLASGYISDRFGRRLTLRLLSVLFIAGALGTAIAPSIPFMVAARFLLGIAVGGGSAT 139 + G +SDRFGRR L + A AP + + R + GI G A Sbjct: 57 FACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAV 115 Query: 140 VPVFIAEIAGPSRRARLVSRNELMIVSGQLLAYVLSAVMAAL-LHTPGIWRYMLAIAMVP 198 +IA+I RAR G + VL +M H P A A + Sbjct: 116 AGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAP-----FFAAAALN 170 Query: 199 GVLLLIGTFFVPPS 212 G+ L G F +P S Sbjct: 171 GLNFLTGCFLLPES 184
>cloacin#Cloacin signature. Length = 551 Score = 31.2 bits (70), Expect = 0.007 Identities = 15/30 (50%), Positives = 17/30 (56%) Query: 101 GIGAGGGGGGIGGAGSGSGVGGGLSSDAGA 130 G G GGG G +G GSG GG LS+ A Sbjct: 58 GGSGHGNGGGNGNSGGGSGTGGNLSAVAAP 87
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 97.3 bits (242), Expect = 5e-25 Identities = 44/177 (24%), Positives = 78/177 (44%), Gaps = 6/177 (3%) Query: 9 LLLCMLLLGGCSDETDLFTGLSEQDSNEVVARLADQHIDARKRLEKTGVVVTVATSEMNR 68 +++ M+L D LF+ LS+QD +VA+L +I R + V +++ Sbjct: 37 IVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIPYR--FANGSGAIEVPADKVHE 94 Query: 69 AVRVLDAAGLPRRSRTTLGEIFKKEGVISTPLEERARYIYALSQELEATLSQIDGVIVAR 128 L GLP+ E+ +E + E+ Y AL EL T+ + V AR Sbjct: 95 LRLRLAQQGLPKGGAVGF-ELLDQEKFGISQFSEQVNYQRALEGELARTIETLGPVKSAR 153 Query: 129 VHVVLPERIAPGEPVQPASAAVFIK--HSAALDPDSVRGRIQQMVASSIPGMSTQSV 183 VH+ +P+ + SA+V + ALD + + +V+S++ G+ +V Sbjct: 154 VHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQISA-VVHLVSSAVAGLPPGNV 209
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 621 bits (1603), Expect = 0.0 Identities = 170/569 (29%), Positives = 269/569 (47%), Gaps = 68/569 (11%) Query: 12 LIGVIPATWAVTPEAWKHTAYAYDARQTELSTALADFAREFGMSLDMSP-VQGKLDGRIR 70 L+ + +WA + W Y Y A+ L L DF + ++ +S + K+ G+ Sbjct: 17 LLLLSSYSWAQELD-WLPIPYVYVAKGESLRDLLTDFGANYDATVVVSDKINDKVSGQFE 75 Query: 71 AQNPEEFLERLSQEYHFQWFVYNDTLYVSPSSEHTSARIEVSPDAVDDLQTALTDVGLLD 130 NP++FL+ ++ Y+ W+ + LY+ +SE S I + +L+ AL G+ + Sbjct: 76 HDNPQDFLQHIASLYNLVWYYDGNVLYIFKNSEVASRLIRLQESEAAELKQALQRSGIWE 135 Query: 131 KRFGWGSLPDEGVVLVRGPAKYVEFVRDYSKKVEKP----DEKADKQDVVVLPLKYANAA 186 RFGW +V V GP +Y+E V + +E+ EK + + PLKYA+A+ Sbjct: 136 PRFGWRPDASNRLVYVSGPPRYLELVEQTAAALEQQTQIRSEKTGALAIEIFPLKYASAS 195 Query: 187 DRTIRYRDQQLVVAGVASILQELLESRSRGESIDSVNLLPGQGSSVANSTGVAAAGLPYN 246 DRTI YRD ++ GVA+ILQ +L + + N Q ++ A+ Sbjct: 196 DRTIHYRDDEVAAPGVATILQRVLSDATIQ-QVTVDNQRIPQAATRAS------------ 242 Query: 247 LGSNGIDTGALQQGIDRVLNFNSKKTAKGHASGKANIRVSADVRNNSVLIYDLPERKAMY 306 A RV AD N++++ D PER MY Sbjct: 243 ----------------------------------AQARVEADPSLNAIIVRDSPERMPMY 268 Query: 307 QKLVKELDVPRNLIEIDAVILDIDRNELAELSSRWNFNA----------GSVGGGANLFD 356 Q+L+ LD P IE+ I+DI+ ++L EL W + G +N+ Sbjct: 269 QRLIHALDKPSARIEVALSIVDINADQLTELGVDWRVGIRTGNNHQVVIKTTGDQSNIAS 328 Query: 357 AGTSSTLF-LQNASKFSAELHALEGNGSASVIGNPSILTLENQPAVIDLSRTEYLTATSE 415 G +L + A ++ LE GSA V+ P++LT EN AVID S T Y+ T + Sbjct: 329 NGALGSLVDARGLDYLLARVNLLENEGSAQVVSRPTLLTQENAQAVIDHSETYYVKVTGK 388 Query: 416 RAADILPITAGTSLQVIPRSLDNDGKPQVQMIVDIEDG-QIDVSTINDTQPSVRRGNVST 474 A++ IT GT L++ PR L K ++ + + IEDG Q S+ + P++ R V T Sbjct: 389 EVAELKGITYGTMLRMTPRVLTQGDKSEISLNLHIEDGNQKPNSSGIEGIPTISRTVVDT 448 Query: 475 QAVIAEHGSLVIGGFHGLEANDRIHKIPLLGDIPYIGKLLFQSRSRELSQRERLFILTPR 534 A + SL+IGG + E + + K+PLLGDIPYIG LF+ +S + RLFI+ PR Sbjct: 449 VARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYIGA-LFRRKSELTRRTVRLFIIEPR 507 Query: 535 LIGDQVNPARYVQNGNPHDVDDQMKKIKE 563 +I + + A ++ GN D+ + + E Sbjct: 508 IIDEGI--AHHLALGNGQDLRTGILTVDE 534
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 407 bits (1048), Expect = e-144 Identities = 112/346 (32%), Positives = 193/346 (55%), Gaps = 4/346 (1%) Query: 2 SEKTEKATPKQIRDAREKGQVGQSQDLGKLLVLLAVSEVTLGLANESVNRLQALLALTFK 61 EKTE+ TPK+IRDAR+KGQV +S+++ +++A+S + +GL++ L+ + + Sbjct: 3 GEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAE 62 Query: 62 GIERPFMSAVELIASEGLSVVLSFTLCSVGLAMLMRLISSWVQIGFLFAPKALKLDIKKI 121 PF A+ + L + +A LM + S VQ GFL + +A+K DIKKI Sbjct: 63 QSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKI 122 Query: 122 DPFSHAKQMFSGQNILNLLLSILKAVAIGATLYTQVKPALGTLILLANSDLATYLHALIE 181 +P AK++FS ++++ L SILK V + ++ +K L TL+ L + L + Sbjct: 123 NPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQ 182 Query: 182 LFQHVLRVILGLLLVIALIDFAMQKYFHAKKLRMSHEDIKKEYKQSEGDPHVKGHRRQLA 241 + + ++ + +VI++ D+A + Y + K+L+MS ++IK+EYK+ EG P +K RRQ Sbjct: 183 ILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQFH 242 Query: 242 HEILNQEPSAAPKPVEEADMLLVNPTHYAVALYYRPGETPLPMIHCKGEDEDALALIAQA 301 EI ++ V+ + +++ NPTH A+ + Y+ GETPLP++ K D + A Sbjct: 243 QEIQSRNMRE---NVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIA 299 Query: 302 KKAGIPVVQSIWLARTLYK-VNVGKYIPRPTLLAVGHIYKVVRQLE 346 ++ G+P++Q I LAR LY V YIP + A + + + + Sbjct: 300 EEEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQN 345
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 167 bits (424), Expect = 4e-53 Identities = 37/237 (15%), Positives = 92/237 (38%), Gaps = 4/237 (1%) Query: 17 LAMARLVPCMLLVPAFCFKYLKGPLRYAVVAVVAMIPAPGISRALTSLNDDWFAIGGLLL 76 + R++ + P + + ++ + ++ AP + + F L + Sbjct: 18 WPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPANDVPVFS--FFALWLAV 75 Query: 77 KEVVLGTLLGMLLYAPFWMFASVGALLDSQRGALSGGQINPSLGPDATPLGELFQETLVM 136 +++++G LG + F + G ++ Q G ++P+ + L + ++ Sbjct: 76 QQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIMDMLALL 135 Query: 137 LVLISGGLSLITQVIWDSYMVWPPTSWLPGMTAEGLDVFLGQLNQTLQHMMLYAAPFIAL 196 L L G + ++ D++ P + + + + ++ A P I L Sbjct: 136 LFLTFNGHLWLISLLVDTFHTLPIGG--EPLNSNAFLALTKAGSLIFLNGLMLALPLITL 193 Query: 197 LLLIEAALAIIGLYAQQLNVSILAMPAKSMAGIAFLLVYLPTLLELGTGELSKLADL 253 LL + AL ++ A QL++ ++ P GI+ + +P + S++ +L Sbjct: 194 LLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEHLFSEIFNL 250
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 73.6 bits (181), Expect = 4e-21 Identities = 28/84 (33%), Positives = 46/84 (54%) Query: 2 EALALFKQGMFLVVILTAPPLGVAVLVGVITSLLQALMQIQDQTLPFGIKLAAVGMTLAM 61 + + + ++LV+IL+ P VA ++G++ L Q + Q+Q+QTLPFGIKL V + L + Sbjct: 3 DLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFL 62 Query: 62 TGRWIGVELIQFINMAFDLIARSG 85 W G L+ + L G Sbjct: 63 LSGWYGEVLLSYGRQVIFLALAKG 86
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 233 bits (596), Expect = 2e-80 Identities = 72/207 (34%), Positives = 123/207 (59%), Gaps = 7/207 (3%) Query: 1 MSLIPFLLIVCTAFLKIAMTLLITRNAIGVQQVPPNMALYGIALAATMFVMAPVAHEMQQ 60 +L+PF++ T F+K ++ ++ RNA+G+QQ+P NM L G+AL +MFVM P+ H+ Sbjct: 14 STLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLSMFVMWPIMHDAYV 73 Query: 61 RVHDHPLELGNTEKLQASARTVIEPLQRFMTRNTDPDVVAHLLDNTQRMWPKEMA----- 115 D + + L ++ + ++ + +D ++V + + E Sbjct: 74 YFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKRQYGEETETVKR 133 Query: 116 --DQASKNDLLLAIPAFVLSELQAGFEIGFLIYIPFIVIDLIVSNLLLALGMQMVSPMTL 173 D+ K + +PA+ LSE+++ F+IGF +Y+PF+V+DL+VS++LLALGM M+SP+T+ Sbjct: 134 DKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVLLALGMMMMSPVTI 193 Query: 174 SLPLKLLLFVMVSGWSRLLDSLFYSYM 200 S P+KL+LFV + GW+ L L YM Sbjct: 194 STPIKLVLFVALDGWTLLSKGLILQYM 220
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 49.6 bits (118), Expect = 4e-10 Identities = 20/82 (24%), Positives = 36/82 (43%) Query: 50 DDEQEEQEEQQAPSGLDSLALDLTLRCGELRLTLAELRRLDAGTILEVGGVAPGYATLCH 109 ++E E + GL+ L + L +TLAEL + +L + A + Sbjct: 212 EEENNTTETAETLPGLNQLPVKLEFVLYRKNVTLAELEAMGQQQLLSLPTNAELNVEIMA 271 Query: 110 GERVVAEGELVDVDGRLGLQIT 131 ++ GELV ++ LG++I Sbjct: 272 NGVLLGNGELVQMNDTLGVEIH 293
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 26.7 bits (59), Expect = 0.011 Identities = 7/49 (14%), Positives = 14/49 (28%) Query: 21 LSLQMPLVHADGGAQLSGAQGQGSAALNSGSGQGGTAQSGSQSGSRDSS 69 L++ +P H S + ++ S G G+ Sbjct: 596 LNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLED 644
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 36.7 bits (85), Expect = 9e-05 Identities = 6/26 (23%), Positives = 17/26 (65%) Query: 239 RRLLVREGQQVKAGQTIAEMGSTGTD 264 + ++V+EG+ V+ G + ++ + G + Sbjct: 108 KEIIVKEGESVRKGDVLLKLTALGAE 133
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 30.3 bits (68), Expect = 0.018 Identities = 21/97 (21%), Positives = 37/97 (38%), Gaps = 15/97 (15%) Query: 23 VLPRKEASRD---DVDET---QKKSIQKQLIRLAKEEGGLISNLGQAIQGLSKILTAYIP 76 ++ + E + D+ Q K + + + I+N + I L+ I Sbjct: 132 LIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQ----INNYAKQIASLNDQ----IS 183 Query: 77 SIQIMSAIGDPLNDLLDAYSHLVSEEGTYLSKAQTVQ 113 + + A G N+LLD LVSE + +VQ Sbjct: 184 RLTGVGA-GASPNNLLDQRDQLVSELNQIVGVEVSVQ 219
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 34.7 bits (79), Expect = 0.002 Identities = 31/205 (15%), Positives = 61/205 (29%), Gaps = 20/205 (9%) Query: 130 PATSPQGLAATRSRNQQRSLNAAQESRMPVAPPAALQGKHYTVASGDTLNGIASRLQGPG 189 P + + S N++ A+ PV PPA T + S+ + Sbjct: 1000 PNNIQADVPSVPSNNEEI----ARVDEAPVPPPAPA-----TPSETTETVAENSKQESKT 1050 Query: 190 GKVSASQMAEAIRALNPQVFAAGAGSALKVGQDLLLPDSAVMPAAATAPAASAVVAPPAE 249 + + E + A A S +K + T E Sbjct: 1051 VEKNEQDATETTA--QNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE-TKETATVE 1107 Query: 250 LQRTAEQLSAAAIENQQLAQSLEALKTQTQELQEQMIGKDKQITALRSDLALAQSAARPA 309 + A+ + E ++ + + Q++ +Q Q + + + P Sbjct: 1108 KEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTV--------NIKEPQ 1159 Query: 310 APATPPAAPAQPAVTVASSSEPLVS 334 + A QPA +S+ E V+ Sbjct: 1160 SQTNTTADTEQPAKETSSNVEQPVT 1184
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 159 bits (403), Expect = 5e-45 Identities = 73/323 (22%), Positives = 110/323 (34%), Gaps = 53/323 (16%) Query: 58 WGLGRIQADQAYAAGMTGAGVKIGALDSGFDPSHPEASPSRFQAVTATGTYVNGTPFSVT 117 G+ IQA + G GVK+ LD+G D HP+ + G F+ Sbjct: 24 RGVEMIQAPAVWNQT-RGRGVKVAVLDTGCDADHPDLK----------ARIIGGRNFTDD 72 Query: 118 GAINPN----NDTHGTHVTGTMGAARDGVEMHGVAYNAQIYVGNTNQNDSFLFGPNPDPQ 173 +P + HGTHV GT+ A + + GVA A + + G Sbjct: 73 DEGDPEIFKDYNGHGTHVAGTIAATENENGVVGVAPEADLLIIKVLNKQ----GSGQYDW 128 Query: 174 YFKAVYGALADAGVRAINNSWGSQPADVTYATESGVRAAYAQHYNRGTWLDEAANVSRKG 233 + +Y A + V I+ S G + V+ A Sbjct: 129 IIQGIYYA-IEQKVDIISMSLG--GPEDVPELHEAVKKAV-----------------ASQ 168 Query: 234 VINVFSAGNSGYANASVRASLPYFEPDLEGHWLAVSGLDASTGQRYNQCGLSKYWCITMP 293 ++ + +AGN G + P ++V ++ + + P Sbjct: 169 ILVMCAAGNEGDGDDRT---DELGYPGCYNEVISVGAIN-FDRHASEFSNSNNEVDLVAP 224 Query: 294 GRLINSTVPGGGYGIKSGTSMSAPHATGALALVMERFPY-----LNNEQALQVLLTTATQ 348 G I STVPGG Y SGTSM+ PH GALAL+ + L + L+ Sbjct: 225 GEDILSTVPGGKYATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIP 284 Query: 349 LDGSVTQAPTTSVGWGVANLERA 371 L S G G+ L Sbjct: 285 LGNS-----PKMEGNGLLYLTAV 302
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 156 bits (396), Expect = 3e-44 Identities = 75/383 (19%), Positives = 120/383 (31%), Gaps = 98/383 (25%) Query: 81 NADWGLGAINADQAYAAGYSGKGIKLGIFDQPVYAPHPEFSSANKVVNLVTSGIREYTDP 140 G+ I A + G+G+K+ + D A HP+ + Sbjct: 21 EIPRGVEMIQAPAVWNQTR-GRGVKVAVLDTGCDADHPDLKAR----------------- 62 Query: 141 YIPVKAGDAFRYDGAPTLDSGGKLGNHGTHVGGIAGGDRDGGPMHGVAYNAQILSA---D 197 + G F D + HGTHV G + + GVA A +L + Sbjct: 63 ---IIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATENENGVVGVAPEADLLIIKVLN 119 Query: 198 NGDPGPEDGIVLGNDGAVYQAGWNALVNSGARVINNSWGIGITDRFDKGGRDPAFPHFTV 257 G D I+ G + +I+ S G G D H Sbjct: 120 KQGSGQYDWII---------QGIYYAIEQKVDIISMSLG---------GPEDVPELH--- 158 Query: 258 QDAQVQFDQIRQILGTRPGGAYQGAIDAARSGVVTIFAAGNDYNLNNPDAMAGLGYFVPG 317 + A S ++ + AAGN+ PG Sbjct: 159 ----------------------EAVKKAVASQILVMCAAGNE----GDGDDRTDELGYPG 192 Query: 318 IAPNWLTVAALQQNPDAAAATTPYTLSTFSSRCGYTASFCVSAPGTRIYSSVLNGTSLED 377 ++V A+ + S FS+ + APG I S+V G Sbjct: 193 CYNEVISVGAINFD---------RHASEFSNSNNEV---DLVAPGEDILSTVPGG----- 235 Query: 378 LTVGWANKNGTSMAAPHVAGSMAVLMERFPY-----MTGAQVADVLKTTATDLGAPGVDA 432 +A +GTSMA PHVAG++A++ + +T ++ L LG Sbjct: 236 ---KYATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLG--NSPK 290 Query: 433 LYGWGMINLGKAVNGPSMFVTEA 455 + G G++ L +F T+ Sbjct: 291 MEGNGLLYLTAVEELSRIFDTQR 313
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.6 bits (66), Expect = 0.037 Identities = 15/88 (17%), Positives = 35/88 (39%), Gaps = 3/88 (3%) Query: 330 EPSDSHESPLQPTTLPAPEVPALTSQTHDEVSEENDEDDEYLALTDLELNTPTLPQLNFG 389 PS++ E P PA S+T + V+E + ++ + + + + T Sbjct: 1010 VPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQN---R 1066 Query: 390 IEDLEDQIDLDHDLQDLSIFELEAEQEE 417 E + ++ + Q + + +E +E Sbjct: 1067 EVAKEAKSNVKANTQTNEVAQSGSETKE 1094
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 43.3 bits (102), Expect = 1e-06 Identities = 31/123 (25%), Positives = 62/123 (50%), Gaps = 3/123 (2%) Query: 66 GALADRFGAAKVVFVGGILYAVGLLCMSMADSPLSLSLSAGLLIGIGLSGTSFSVILGVV 125 G L+D+ G +++ G I+ G + + S SL + A + G G + ++++ VV Sbjct: 70 GKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAG-AAAFPALVMVVV 128 Query: 126 GRALPAEKRSMGMGIASAAGSFGQFAMLPGTLGLIS-WLGWSGALLVLGVMVALILPLVG 184 R +P E R G+ + + G+ + P G+I+ ++ WS LL+ + + + L+ Sbjct: 129 ARYIPKENRGKAFGLIGSIVAMGE-GVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMK 187 Query: 185 MLK 187 +LK Sbjct: 188 LLK 190 Score = 34.5 bits (79), Expect = 7e-04 Identities = 23/139 (16%), Positives = 48/139 (34%), Gaps = 12/139 (8%) Query: 11 ILLGSALILALSLGTRHGFGLFLAPMSADFGWGREVFAFAIALQNLMWGLAQPFAGALAD 70 + G ++ + H V F + +++G G L D Sbjct: 271 TVAGFVSMVPYMMKDVHQLSTAEIG---------SVIIFPGTMSVIIFG---YIGGILVD 318 Query: 71 RFGAAKVVFVGGILYAVGLLCMSMADSPLSLSLSAGLLIGIGLSGTSFSVILGVVGRALP 130 R G V+ +G +V L S S ++ ++ +G + +VI +V +L Sbjct: 319 RRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLK 378 Query: 131 AEKRSMGMGIASAAGSFGQ 149 ++ GM + + + Sbjct: 379 QQEAGAGMSLLNFTSFLSE 397
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 28.0 bits (62), Expect = 0.020 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 1/47 (2%) Query: 1 MKIRFVSIPLLLLSMSGAVMAADCPPLLQGELPKLRAKENIDLCKRF 47 MK++ V+ ++ L+MS A+ A D L + KL DL K F Sbjct: 1 MKMKLVTAAIMGLAMSTAMAATD-ATSLTTDKDKLSYSIGADLGKNF 46
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.0 bits (104), Expect = 1e-06 Identities = 35/216 (16%), Positives = 69/216 (31%), Gaps = 32/216 (14%) Query: 19 LLALLWQLQRRLALRQAESALLDERLSTAQMAQEGLNAQLDASRDEVSDLGQANAAKQAD 78 +L L L + +S+LL RL + + +L+ + + Sbjct: 123 VLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPE------LKLPDEPYF 176 Query: 79 LAALRREVELLRQDSENARETAQGWSHERASREAELRRLDAHCAALNAELR---EQQDSH 135 EV L + T W +++ +E L + A + A + Sbjct: 177 QNVSEEEVLRLTSLIKEQFST---WQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 136 QQRLNDLQ-------GSRDELRAQFAELAGKIFDEREQRFAETSQQ--QLGQLLTPLKER 186 + RL+D ++ + Q + E Q Q+ + KE Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYV-----EAVNELRVYKSQLEQIESEILSAKEE 288 Query: 187 IQSFEKRVEESYQNEARERFSLAKELERLQQLNLRL 222 Q V + ++NE ++ L + + + L L L Sbjct: 289 YQ----LVTQLFKNEILDK--LRQTTDNIGLLTLEL 318
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 33.6 bits (77), Expect = 0.002 Identities = 18/41 (43%), Positives = 24/41 (58%), Gaps = 3/41 (7%) Query: 341 DAHRALRMA---TLNGARALGIQAEAGSLELGKAADMVAFD 378 D R R T+N A A G+ E GSLE+GK AD+V ++ Sbjct: 398 DNFRVKRYIAKYTINPAIAHGLSHEIGSLEVGKRADLVLWN 438
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.0 bits (70), Expect = 0.022 Identities = 24/137 (17%), Positives = 50/137 (36%), Gaps = 9/137 (6%) Query: 397 LIKASPTPAEAKEALIKTPWESSAVVEMVERAGADSCRPE-NLDPQYGLREGKYF--LSP 453 L+K + AEA ++ + + R S E N P+ L + YF +S Sbjct: 124 LLKLTALGAEADTLKTQSSLLQARL--EQTRYQILSRSIELNKLPELKLPDEPYFQNVSE 181 Query: 454 EQAQAILELRLHRLTGLEHEKLLGE--YQEILAQIGELIRILNSATRLMEVIREELELIR 511 E+ + L + + +++K E + A+ ++ +N L V + L+ Sbjct: 182 EEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFS 241 Query: 512 --AEYGDARRTEILDAR 526 + +L+ Sbjct: 242 SLLHKQAIAKHAVLEQE 258
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 28.9 bits (64), Expect = 0.035 Identities = 26/142 (18%), Positives = 47/142 (33%), Gaps = 22/142 (15%) Query: 128 EVFREVVAGAVN-----FGVVPVENSTEGAVNHTLDSFLEHDMVICGEVELRIHHHLLVG 182 E V AGA+N + + + G + + + + E + + L Sbjct: 226 EFINGVAAGALNPFISAGEALGIGDILYGTRYAIDKAAMRNIAPLPAEGKFAVIGGLGSV 285 Query: 183 ESTKTQSISRIYSHAQSLAQCRKWLDAHYPNV-ERVAVASN-AEAAKRVK----GEWNSA 236 + + + +W+ + PN E V N A AAK K + A Sbjct: 286 AGFEKNTREAV----------DRWIQEN-PNAAETVEAVFNVAAAAKVAKLAKAAKPGKA 334 Query: 237 AIAGDMAAGLYGLTRLAEKIED 258 A++GD A L++ Sbjct: 335 AVSGDFADSYKKKLALSDSARQ 356
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 29.0 bits (64), Expect = 0.026 Identities = 22/93 (23%), Positives = 33/93 (35%) Query: 198 ATAEGLIPAQSFIVANDQAIKDKRAQISDFLQRLQAARAWSVSDPQHNERYANAWAALTK 257 A GLI + QAI D A + L + A + ++ R A W T Sbjct: 262 AAGRGLIQVAQGAASLAQAISDAIAVLGRVLASAPSVMAVGFASLTYSSRTAEQWQDQTP 321 Query: 258 ADAQVARRWFSRALVVVVPITPQVVAGAQQTID 290 + A + L + + VA A T+D Sbjct: 322 DSVRYALGMDAAKLGLPPSVNLNAVAKASGTVD 354
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 54.5 bits (131), Expect = 2e-10 Identities = 21/123 (17%), Positives = 51/123 (41%), Gaps = 14/123 (11%) Query: 180 RVLTVDDSSVARKQVSRCLETVGVEVVALNDGRQALDYLLKMVAEGKKPEEEFLMMISDI 239 +L DD + R +++ L G +V ++ ++ + ++++D+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA---------AGDGDLVVTDV 55 Query: 240 EMPEMDGYTLTAAIRN-DPRMQKMHITLHTSLSGVFNQAMVKKVGADDFLAK-FRPDDLA 297 MP+ + + L I+ P + + ++ + +A + GA D+L K F +L Sbjct: 56 VMPDENAFDLLPRIKKARPDLPVLVMSAQNTFM-TAIKAS--EKGAYDYLPKPFDLTELI 112 Query: 298 ARV 300 + Sbjct: 113 GII 115
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 34.5 bits (79), Expect = 9e-05 Identities = 8/38 (21%), Positives = 21/38 (55%) Query: 107 NVNVVEEMADMISASRSFQTNAEIMNTAKSMMQKVLTL 144 VN+ EE ++ + + NA+++ TA ++ ++ + Sbjct: 508 GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545 Score = 28.0 bits (62), Expect = 0.013 Identities = 18/72 (25%), Positives = 29/72 (40%), Gaps = 14/72 (19%) Query: 8 NIAGSAMSAQTTRLNTTASNIANAETVSSSMDQTYRARHPVFATVMQGQQSTGGSLFQDQ 67 N A S ++A LNT ++NI++ + T + Q + S Sbjct: 5 NNAMSGLNAAQAALNTASNNISSYNVAGYTRQ-----------TTIMAQAN---STLGAG 50 Query: 68 GEAGQGVQVNGI 79 G G GV V+G+ Sbjct: 51 GWVGNGVYVSGV 62
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 41.5 bits (97), Expect = 5e-06 Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Query: 2 SFNIGLSGLYAANKSLDVTGNNIANVATTGFKSSRAEFADQYAQSIRGTSGQTNVGSGVS 61 N +SGL AA +L+ NNI++ G+ A + VG+GV Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANST----LGAGGWVGNGVY 58 Query: 62 TAAVSQQFSQ 71 + V +++ Sbjct: 59 VSGVQREYDA 68 Score = 36.9 bits (85), Expect = 1e-04 Identities = 15/47 (31%), Positives = 23/47 (48%) Query: 394 ITGQALEESNVDLTMELVNLIKAQSNYQANAKTISTQSTIMQTTIQM 440 ++ Q S V+L E NL + Q Y ANA+ + T + I I + Sbjct: 499 LSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 36.5 bits (84), Expect = 3e-04 Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 4/54 (7%) Query: 2 SFNTAISGINAANKRLEVAGNNIANSGTIGFKSSRA----QFSALYSSAQLGSG 51 N A+SG+NAA L A NNI++ G+ S L + +G+G Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNG 56 Score = 33.0 bits (75), Expect = 0.003 Identities = 12/41 (29%), Positives = 18/41 (43%) Query: 544 LEGSNVVLADELIALIQAQTAYQANSKAISTEATVMQTLIQ 584 S V L +E L + Q Y AN++ + T + LI Sbjct: 504 QSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 42.6 bits (100), Expect = 9e-07 Identities = 12/41 (29%), Positives = 20/41 (48%) Query: 220 LENSNVSTVEELVNMITTQRAYEMNSKVISTADQMLQNLTQ 260 S V+ EE N+ Q+ Y N++V+ TA+ + L Sbjct: 504 QSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544 Score = 39.6 bits (92), Expect = 1e-05 Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 14/75 (18%) Query: 5 LYVAKTGLAAQDTNLTTISNNLANVSTTGFKSDRAEFQDLLYQIKRQPGAQSTQDSELPS 64 + A +GL A L T SNN+++ + G+ RQ + +S L + Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGY--------------TRQTTIMAQANSTLGA 49 Query: 65 GLQLGTGVRIVGTQK 79 G +G GV + G Q+ Sbjct: 50 GGWVGNGVYVSGVQR 64
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 174 bits (442), Expect = 1e-56 Identities = 78/236 (33%), Positives = 117/236 (49%), Gaps = 19/236 (8%) Query: 6 FPRFSVLIASLCGITLLSGCVAPTAKPNDPYYAPVLPRTPMSAASNNGAIYQAGF----- 60 + S+L+ SL +GC + P P + +N G+I+Q+ Sbjct: 9 YAISSLLVLSL------TGCAWIPSTPLVQGATSAQPVPGPTPVAN-GSIFQSAQPINYG 61 Query: 61 EQNLYGDRKAFRVGDIITITLSERMAASKAATSAMSKDSTNSIGLTSLFGSGLTTNNPIG 120 Q L+ DR+ +GD +TI L E ++ASK++++ S+D + G + G Sbjct: 62 YQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDT---VPRYLQGLFG 118 Query: 121 GNDLSLSAGYNGARTTKGDGKAAQSNSLTGSVTVTVADVLPNGILSVRGEKWMTLNTGDE 180 + +G T G G A SN+ +G++TVTV VL NG L V GEK + +N G E Sbjct: 119 NARADV--EASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTE 176 Query: 181 LVRIAGLVRADDIATDNTVSSTRIADARITYSGTGAFADTSQPGWFDRFF--LSPL 234 +R +G+V I+ NTV ST++ADARI Y G G + GW RFF LSP+ Sbjct: 177 FIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 433 bits (1114), Expect = e-154 Identities = 164/366 (44%), Positives = 218/366 (59%), Gaps = 10/366 (2%) Query: 7 LIAATLLLSAAFGAHAERLKDIASISGVRANQLIGYGLVVGLNGTGDQTTQTPFTLQTFN 66 A L + A R+KDIAS+ R NQLIGYGLVVGL GTGD +PFT Q+ Sbjct: 13 FSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMR 72 Query: 67 NMLSQFGIKVPAGSGTVQLKNVAAVAVYADLPAFAKPGQTVDITVSSIGNSKSLRGGALL 126 ML GI G KN+AAV V A+LP FA PG VD+TVSS+G++ SLRGG L+ Sbjct: 73 AMLQNLGITTQGGQS--NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLI 130 Query: 127 MTPMKGVDGNVYAIAQGNLVVGGFDAEGRDGSKITVNVPSSGRIPGGASVERSVPSGFNQ 186 MT + G DG +YA+AQG L+V GF A+G D + +T V +S R+P GA +ER +PS F Sbjct: 131 MTSLSGADGQIYAVAQGALIVNGFSAQG-DAATLTQGVTTSARVPNGAIIERELPSKFKD 189 Query: 187 GNTLTLNLNRSDFTTAKRVVDKINEL----LGPGVAQALDGGSVRVTAPLDPGQRVDYLS 242 L L L DF+TA RV D +N G +A+ D + V P ++ Sbjct: 190 SVNLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKP-RVADLTRLMA 248 Query: 243 ILENLEVDPGQTAAKVIINSRTGTIVIGQNVKVSPAAVTHGSLTVTITEDPIVSQPGALS 302 +ENL V+ T AKV+IN RTGTIVIG +V++S AV++G+LTV +TE P V QP S Sbjct: 249 EIENLTVET-DTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPFS 307 Query: 303 GGQTAVVPRSRVNAQQELHPMFKFGPGTTLDEIVRAVNQVGAAPGDLMAILEALKQAGAL 362 GQTAV P++ + A QE + G L +V +N +G ++AIL+ +K AGAL Sbjct: 308 RGQTAVQPQTDIMAMQEGSKVA-IVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGAL 366 Query: 363 QADLIV 368 QA+L++ Sbjct: 367 QAELVL 372
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 126 bits (318), Expect = 2e-35 Identities = 66/161 (40%), Positives = 99/161 (61%), Gaps = 1/161 (0%) Query: 253 NADQFVETMLPLAKEAAARIGVDPVMLVAQAALETGWGKSIMRQQDGSSSHNLFGIKAAG 312 ++ F+ + A+ A+ + GV +++AQAALE+GWG+ +R+++G S+NLFG+KA+G Sbjct: 148 DSKAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASG 207 Query: 313 SWKGAEARAITSEFRDGKMVKETADFRSYDSYADSFHDLVSLLQNNNRYKDVVNSADKPE 372 +WKG T+E+ +G+ K A FR Y SY ++ D V LL N RY V +A E Sbjct: 208 NWKGPVTEITTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYA-AVTTAASAE 266 Query: 373 QFVKELQKAGYATDPAYASKISQIAKQMKSYQTYAAATGSS 413 Q + LQ AGYATDP YA K++ + +QMKS + T S Sbjct: 267 QGAQALQDAGYATDPHYARKLTNMIQQMKSISDKVSKTYSM 307 Score = 57.4 bits (138), Expect = 3e-11 Identities = 30/77 (38%), Positives = 49/77 (63%), Gaps = 4/77 (5%) Query: 31 KDSVANQKKVAQEFESLFVSQMLKAMRSANEVLAKDNPMNTPATRQYQDMYDQQLAVTLS 90 +D AN + VA++ E +FV MLK+MR A KD ++ TR Y MYDQQ+A ++ Sbjct: 27 EDPAANIRPVARQVEGMFVQMMLKSMRDAL---PKDGLFSSEHTRLYTSMYDQQIAQQMT 83 Query: 91 TRGNGIGLQDVLMRQLS 107 G G+GL +++++Q++ Sbjct: 84 A-GKGLGLAEMMVKQMT 99
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 192 bits (490), Expect = 1e-55 Identities = 139/447 (31%), Positives = 227/447 (50%), Gaps = 17/447 (3%) Query: 2 SLISIGLSGINASSAAINTIGNNTANVDTAGYSRQQVMTTASAQINIGLGVGYIGTGTTL 61 SLI+ +SG+NA+ AA+NT NN ++ + AGY+RQ + + G++G G + Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTT--IMAQANSTLGAGGWVGNGVYV 59 Query: 62 SDVRRIYNGYLDAQLQTSTALSADAVAYSGQASKTDTLLSDSATGVSTQLADFFTKMQGI 121 S V+R Y+ ++ QL+ + S+ A Q SK D +LS S + ++TQ+ DFFT +Q + Sbjct: 60 SGVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTL 119 Query: 122 ATNATQSSDRSSFLTQASALSSRFNSVASQLSSQNDNVNAQLTTFTKQVNELTTTLASLN 181 +NA + R + + ++ L ++F + L Q+ VN + Q+N +ASLN Sbjct: 120 VSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLN 179 Query: 182 KQI--TQAGAGNTTPNSLLDSRNEAVRQLNGLVGVKV-VENNGNYDIYTGTGQSLVSGGT 238 QI +PN+LLD R++ V +LN +VGV+V V++ G Y+I G SLV G T Sbjct: 180 DQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGST 239 Query: 239 SYTMSATPSPADPLQYNVQIAYGQTKTDVT--SVITGGSIGGLLRYRSDVLVPATNELGR 296 + ++A PS ADP + V G ++ GS+GG+L +RS L N LG+ Sbjct: 240 ARQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQ 299 Query: 297 AAMVLADQVNSQMSQGIDSKGNFGSSLYANINSADAISQRSTGKTTNSAGSGNLDVTIGD 356 A+ A+ N+Q G D+ G+ G + AI + + + T + G + T+ D Sbjct: 300 LALAFAEAFNTQHKAGFDANGDAGEDFF-------AIGKPAVLQNTKNKGDVAIGATVTD 352 Query: 357 TSKLTADDYEVTFNDASNFTVRRLPNGESVGTGALTDNPPKQFDGFSVSLKGNALAAGDI 416 S + A DY+++F D + + V R + T N FDG ++ A D Sbjct: 353 ASAVLATDYKISF-DNNQWQVTR-LASNTTFTVTPDANGKVAFDGLELTF-TGTPAVNDS 409 Query: 417 FKVTPTRNGASGISVVLTDPKDIAAAA 443 F + P + + V++TD IA A+ Sbjct: 410 FTLKPVSDAIVNMDVLITDEAKIAMAS 436 Score = 72.7 bits (178), Expect = 2e-15 Identities = 50/148 (33%), Positives = 73/148 (49%), Gaps = 11/148 (7%) Query: 544 TTTPASKTAFEVQMTLSGSPLAN----DTFSIGLTG---AGSSDNRNALAIVGLQTAKTV 596 T TPA +F ++ + D I + AG SDNRN A++ LQ+ Sbjct: 401 TGTPAVNDSFTLKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKT 460 Query: 597 GVTNGGVGTSLSGAYSDLVSVVGTLAGQGKSDVTASAAVVAQAKSARDSVSGVSLDEEAA 656 S + AY+ LVS +G K+ VV Q + + S+SGV+LDEE Sbjct: 461 VGGA----KSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYG 516 Query: 657 NLIKYQQYYTASSQIIKAAQTIFSTLIN 684 NL ++QQYY A++Q+++ A IF LIN Sbjct: 517 NLQRFQQYYLANAQVLQTANAIFDALIN 544
>FLAGELLIN#Flagellin signature. Length = 507 Score = 61.2 bits (148), Expect = 4e-12 Identities = 67/455 (14%), Positives = 139/455 (30%), Gaps = 6/455 (1%) Query: 1 MRISTTQFFESTNANYQRNYANVIKTGDEVTSGIKLNTASDDPVGAARVLQLAQQNSMLT 60 I+T T N ++ +++ + ++SG+++N+A DD G A + LT Sbjct: 2 QVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLT 61 Query: 61 QYASNIGTINTNIVNSETALTSIVDTMQAAREVVVSAGNGAYTDSDRLAKAAELKQYQSQ 120 Q + N + +E AL I + +Q RE+ V A NG +DSD + E++Q + Sbjct: 62 QASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEE 121 Query: 121 ILGLMNSQDANGQYIFAGSKSSAPPYAQNADGTYSYSGDQTSVNLAIGDGLVLPSNTTGH 180 I + N NG + + N T + + V DG + Sbjct: 122 IDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEAT 181 Query: 181 EAFEQAVNTTRTSSTLLSPATDDGKVGLTGGQVKSTSAYNAGYQAGEPYTMTFLSGTQFK 240 + ++ + T + + + +G Sbjct: 182 VG---DLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTT 238 Query: 241 ITDATGTDVTTDASSAGKFNYASFSDQTFTFRGVELTMNVNLSAAESATAATAATALTNR 300 T V ++ A +G + + + Sbjct: 239 DDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGK 298 Query: 301 SYELASTPDTVSASRSPGNTSAATISSSAVGNTTADRTAFNNTFPPNGAILKFTSATAYD 360 + +A +++ + + N F + ++ + Sbjct: 299 VSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLS-- 356 Query: 361 LYASPVTSSSKPVSSGTLTGSTANASGVNFTVSGTPAAGDQFVVESGTHQTENILNTLTA 420 + + + TANA+G T++G D+ T E+ + Sbjct: 357 DLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKS 416 Query: 421 AIKALSTPTDGNLVASQKLDAALGSALGNISSSID 455 L++ D L + ++LG+ S+I Sbjct: 417 TANPLAS-IDSALSKVDAVRSSLGAIQNRFDSAIT 450
>FLAGELLIN#Flagellin signature. Length = 507 Score = 118 bits (297), Expect = 2e-32 Identities = 90/272 (33%), Positives = 132/272 (48%), Gaps = 3/272 (1%) Query: 2 ALTVNTNVASLNVQKNLGRASDALSTSMTRLSSGLKINSAKDDAAGLQIATKITSQIRGQ 61 A +NTN SL Q NL ++ +LS+++ RLSSGL+INSAKDDAAG IA + TS I+G Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 TMAIKNANDGMSLAQTAEGALQESTNILQRMRELAVQSRNDSNSATDREALNKEFTAMSS 121 T A +NANDG+S+AQT EGAL E N LQR+REL+VQ+ N +NS +D +++ E Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 ELTRIAQSTNLNGKNLLDGSASTMTFQVGSNSGASNQISLTLSASFDANTLGVGSAISIT 181 E+ R++ T NG +L M QVG+N G I++ L + G ++ Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQ-MKIQVGANDG--ETITIDLQKIDVKSLGLDGFNVNGP 177 Query: 182 GADSATSEAAFSAAVAAIDSALQTINSTRADLGAAQNRLTSTISNLQNINENASAALGRV 241 + + V D+ N R D+ + +T + + +A Sbjct: 178 KEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLT 237 Query: 242 QDTDFAAETAQLTKQQTLQQASTSVLAQANQL 273 D L K + A A + Sbjct: 238 TDDAENNTAVDLFKTTKSTAGTAEAKAIAGAI 269 Score = 73.2 bits (179), Expect = 9e-17 Identities = 51/142 (35%), Positives = 80/142 (56%) Query: 141 SASTMTFQVGSNSGASNQISLTLSASFDANTLGVGSAISITGADSATSEAAFSAAVAAID 200 S +T + + +TL+ ++ D+A ++ + + +A+ID Sbjct: 366 GESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPLASID 425 Query: 201 SALQTINSTRADLGAAQNRLTSTISNLQNINENASAALGRVQDTDFAAETAQLTKQQTLQ 260 SAL +++ R+ LGA QNR S I+NL N N ++A R++D D+A E + ++K Q LQ Sbjct: 426 SALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKAQILQ 485 Query: 261 QASTSVLAQANQLPSAVLKLLQ 282 QA TSVLAQANQ+P VL LL+ Sbjct: 486 QAGTSVLAQANQVPQNVLSLLR 507
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 51.3 bits (122), Expect = 6e-10 Identities = 48/201 (23%), Positives = 89/201 (44%), Gaps = 17/201 (8%) Query: 37 PEPEPEPVDEPAEMEEVPLDEVQPLTLEELESIRQEAWNEGF------------ATGEKE 84 P+ E P+ EP EE ++E +P ++L ++ +A +G+ G +E Sbjct: 18 PQAEFVPIVEP---EETIIEEAEPSLEQQLAQLQMQAHEQGYQAGIAEGRQQGHKQGYQE 74 Query: 85 GFHSTQLKVRQEAEVVLAAKVASLEQLMGHLLAPIAEQDTQIEKAVIHLVEHIARQVIQR 144 G + EA+ A A ++QL+ + D+ I ++ + ARQVI + Sbjct: 75 GLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVIGQ 134 Query: 145 ELVTDSGQIASVLRDALKLLPMGAQNLRIFINPQDFLLVKAM--RERHEEAWKIVEDEDL 202 D+ + ++ L+ P+ + ++ ++P D V M W++ D L Sbjct: 135 TPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGATLSLHGWRLRGDPTL 194 Query: 203 LPGGCRIETEHSRIDASVETR 223 PGGC++ + +DASV TR Sbjct: 195 HPGGCKVSADEGDLDASVATR 215
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 43.7 bits (102), Expect = 3e-08 Identities = 36/134 (26%), Positives = 69/134 (51%) Query: 9 LAPVVEMAEAAERTAAQRLGHFQGQVNLANNKLQELDQFRQDYQQQWLQRGSAGVSGQWL 68 LA + ++AE AA+ LG + A +L+ L ++ +Y+ SAG++ Sbjct: 7 LATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAGITSNRW 66 Query: 69 LGYQRFLSQLDVAVAQQYKSLEWHKANLDRARSAWQDCYARVEGLRKLVQRYMDEARRLE 128 + YQ+F+ L+ A+ Q + L +D A ++W++ R++ + L +R A E Sbjct: 67 INYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQSTAALLAE 126 Query: 129 DKREQKLLDELSQR 142 ++ +QK +DE +QR Sbjct: 127 NRLDQKKMDEFAQR 140
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 71.0 bits (174), Expect = 4e-15 Identities = 29/133 (21%), Positives = 58/133 (43%), Gaps = 3/133 (2%) Query: 10 ILIADDSASDRVLLSTIVARQGHRVLCAANGVEAVAIFMAESPQLILMDAMMPVMDGFEA 69 IL+ADD A+ R +L+ ++R G+ V +N A L++ D +MP + F+ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 70 ARRIKALTGESLVPIIFLTSLTEGEALARCLDAGGDDFMSKPYNPLVLAAKI-NAMNRLR 128 RIK + +P++ +++ + + G D++ KP++ L I A+ + Sbjct: 66 LPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 129 VLHETVRLQRDQI 141 + Sbjct: 124 RRPSKLEDDSQDG 136
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 48.7 bits (115), Expect = 3e-08 Identities = 51/178 (28%), Positives = 84/178 (47%), Gaps = 12/178 (6%) Query: 298 AALSQAAQPARAVAAP-ASAPLMNQPLAMHQSGWTEGIVDRVMYLSSQNLKTADIKLEPA 356 AA S P + P +AP+++ PL H+ W + + + + Q ++A+++L P Sbjct: 209 AAASPLITPHQTQPLPTVAAPVLSAPLGSHE--WQQSLSQHISLFTRQGQQSAELRLHPQ 266 Query: 357 ELGRLDIRINMAPEQQTQVTFMSAHMGVRDALESQMSKLRESFVQQGLGNVDVNVSDQSQ 416 +LG + I + + + Q Q+ +S H VR ALE+ + LR + G+ N+S +S Sbjct: 267 DLGEVQISLKV-DDNQAQIQMVSPHQHVRAALEAALPVLRTQLAESGIQLGQSNISGESF 325 Query: 417 QQAQQQAQEQASRAQRSGRGNGVGSSDTSDDIAGVDAAIPVSQPAARVIGTSEIDYYA 474 QQ A +Q Q+S R DD +PVS RV G S +D +A Sbjct: 326 SGQQQAASQQ----QQSQRTANHEPLAGEDDDT---LPVPVSL-QGRVTGNSGVDIFA 375
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 252 bits (645), Expect = 2e-84 Identities = 95/324 (29%), Positives = 164/324 (50%), Gaps = 11/324 (3%) Query: 5 DLLSQDEIDALLHGVDDGMVQ----TDIASEPGSVKSYDLTSQDRIVRGRMPTLEMINER 60 ++LSQDEID LL + G I+ + YD D+ + +M TL +++E Sbjct: 3 EVLSQDEIDQLLTAISSGDASIEDARPISDTR-KITLYDFRRPDKFSKEQMRTLSLMHET 61 Query: 61 FARYTRISMFNLLRRSADVAVGGVQVMKFGEYVHSLYVPTSLNLAKIKPLRGTALFILDA 120 FAR T S+ LR V V V + + E++ S+ P++L + + PL+G A+ +D Sbjct: 62 FARLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVDP 121 Query: 121 KLVFKLVDNFFGGDGRHAKIEGREFTPTELRVVRMVLDQAFIDLKEAWQAIMEVNFEYIN 180 + F ++D FGG G+ AK++ R+ T E V+ V+ + +++E+W ++++ Sbjct: 122 SITFSIIDRLFGGTGQAAKVQ-RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRLGQ 180 Query: 181 SEVNPAMANIVGPSEAVVISTFHIELDGGGGDLHVTMPYSMIEPIREMLDAGF--QSDLD 238 E NP A IV PSE VV+ T ++ G ++ +PY IEPI L + F S Sbjct: 181 IETNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVRR 240 Query: 239 DQDERWVNALKEDVLDVNVPLTTTIAQRQLPLRDILHMRPGDVIPVE---LSDTLVLRAN 295 +++ L++ + V++ + + +L +RDIL +R GD+I + + D VL Sbjct: 241 SSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIG 300 Query: 296 GVPSFKVKLGSHKGKMALQVIEPI 319 F + G K+A Q++E I Sbjct: 301 NRKKFLCQPGVVGKKIAAQILERI 324
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 120 bits (302), Expect = 6e-38 Identities = 65/151 (43%), Positives = 95/151 (62%), Gaps = 16/151 (10%) Query: 1 MADENDMTSAEDQALADEWAAALGEAGDSQADIDALLAADAGNSGSRMTMEEFGSVPKSA 60 M+D N+ + AL D WA AL E A S + ++ G Sbjct: 1 MSDMNNPSDENTGALDDLWADALNEQ-----------KATTTKSAADAVFQQLG-----G 44 Query: 61 GPVTLDGPNLDVILDIPVSISMEVGSTDINIRNLLQLNQGSVIELDRLAGEPLDVLVNGT 120 G V+ ++D+I+DIPV +++E+G T + I+ LL+L QGSV+ LD LAGEPLD+L+NG Sbjct: 45 GDVSGAMQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGY 104 Query: 121 LIAHGEVVVVNEKFGIRLTDVISPSERIKKL 151 LIA GEVVVV +K+G+R+TD+I+PSER+++L Sbjct: 105 LIAQGEVVVVADKYGVRITDIITPSERMRRL 135
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 261 bits (668), Expect = 2e-90 Identities = 136/247 (55%), Positives = 180/247 (72%), Gaps = 4/247 (1%) Query: 1 MGALRFLILLMLAVVAPAALAADPLSIPAITLSNGADGQQEYSVSLQILLIMTALSFIPA 60 M L + ++L ++ P A A +P IT G Q +S+ +Q L+ +T+L+FIPA Sbjct: 1 MRRLLSVAPVLLWLITPLAFAQ----LPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPA 56 Query: 61 FVMLMTSFTRIIIVFSILRQALGLQQTPSNQILTGMALFLTMFIMAPVFDRVNQDALQPY 120 +++MTSFTRIIIVF +LR ALG P NQ+L G+ALFLT FIM+PV D++ DA QP+ Sbjct: 57 ILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPF 116 Query: 121 LAEKLTAQDAVAKAQVPIKDFMLAQTRTSDLELFMRLSKRTDIPTPDAAPLTILVPAFVI 180 EK++ Q+A+ K P+++FML QTR +DL LF RL+ + P+A P+ IL+PA+V Sbjct: 117 SEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVT 176 Query: 181 SELKTAFQIGFMIFIPFLIIDLVVASVLMAMGMMMLSPLIISLPFKIMLFVLVDGWALIV 240 SELKTAFQIGF IFIPFLIIDLV+ASVLMA+GMMM+ P I+LPFK+MLFVLVDGW L+V Sbjct: 177 SELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLV 236 Query: 241 GTLAGSF 247 G+LA SF Sbjct: 237 GSLAQSF 243
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 49.4 bits (118), Expect = 1e-11 Identities = 23/74 (31%), Positives = 40/74 (54%) Query: 7 VDLFREALWLTTVLVAILVVPSLLCGLLVAMFQAATQINEQTLSFLPRLLVMLVTLIVIG 66 V +AL+L +L + + + GLLV +FQ TQ+ EQTL F +LL + + L ++ Sbjct: 5 VFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFLLS 64 Query: 67 PWLLKIFMEYMLSL 80 W ++ + Y + Sbjct: 65 GWYGEVLLSYGRQV 78
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 27.5 bits (61), Expect = 0.048 Identities = 15/52 (28%), Positives = 27/52 (51%), Gaps = 7/52 (13%) Query: 169 LM--LAFGLGTWPVLLATGLAAERTTALLRKRGVRVAGGLLV-IVFGVWTLP 217 LM LAF LG P+ ++ G + A+ G+ V GG++ + ++ +P Sbjct: 975 LMTSLAFILGVLPLAISNGAGSGAQNAV----GIGVMGGMVSATLLAIFFVP 1022
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 30.1 bits (68), Expect = 0.013 Identities = 21/79 (26%), Positives = 31/79 (39%), Gaps = 21/79 (26%) Query: 146 AGAPMDSEFMNSMAMHLAAQGIGVLRFEFPYMAQRREGGSKRPPNPQAQLLACWREVYAQ 205 G P D + + +GIG+ R EF YM + P + Q E Y + Sbjct: 276 IGTPKDVD----GVLANGGEGIGLYRTEFLYM------DRDQLPTEEEQF-----EAYKE 320 Query: 206 V------RPLVAGRLAVGG 218 V +P+V L +GG Sbjct: 321 VVQRMDGKPVVIRTLDIGG 339
>INTIMIN#Intimin signature. Length = 939 Score = 52.4 bits (125), Expect = 4e-09 Identities = 74/363 (20%), Positives = 136/363 (37%), Gaps = 56/363 (15%) Query: 271 SDTKEKTLTSAEAGQALE----VLFAAVLVTANAGQTVSVSYVVNRT-NGLVQVSDTLAL 325 S+ T+T GQ ++ F A +A A T +++Y NG+ Q + ++ Sbjct: 539 SNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSF 598 Query: 326 QVVSGLAELPAPRMDTVGADGVVTPSLIPGYGATVRVSYPGVGAQDSV------VVNWRG 379 +VSG A L A +T G T +L V VS ++ V+ Sbjct: 599 NIVSGTAVLSANSANT-NGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTK 657 Query: 380 ASSHDTAA-----------------------QVAGGGELQFN---VPKALISATAGRS-- 411 AS + A + E+ F + + + Sbjct: 658 ASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGY 717 Query: 412 ATVTYTVTRAGEPTVSTAL---QLSVRQELVLDTSPVTL-AGKIYLLPGSPD--LLPNFP 465 A VT T T G+ VS + + V+ V + +T+ G I ++ L + Sbjct: 718 AKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWL 777 Query: 466 ADTTVQRQASGGHAPYRYASSNPLVVSVDGN-GLASVRGKGTATITATDALGATKSYPVT 524 V +ASGG+ Y + S+NP + SVD + G +++ KGT TI+ + T +Y + Sbjct: 778 QYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTIA 837 Query: 525 VTG--VIHCIGVGSGSFSQISKASANNGARIPTIHELVEIYALYG--NRWPMGNGNYWSS 580 ++ + ++ G + +EL ++ +G N++ Y+ S Sbjct: 838 TPNSLIVPNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGAANKYE-----YYKS 892 Query: 581 TVS 583 + + Sbjct: 893 SQT 895
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 57.9 bits (140), Expect = 5e-12 Identities = 28/144 (19%), Positives = 47/144 (32%), Gaps = 5/144 (3%) Query: 6 RLVLADDHEVTRTGFVSLLAGHPEFEVVGQAADGQQAIDLCQALQPDIAILDIRMPVLNG 65 +++ADD RT L+ V ++ A D+ + D+ MP N Sbjct: 5 TILVADDDAAIRTVLNQALSR--AGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 66 LGAARILQQRMPGLKVVIFTMDDSTDHLEAAISAGAVGYLLKDASRDEVIDGLQRVARGE 125 +++ P L V++ + ++ A GA YL K E+I + R Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIG---IIGRAL 119 Query: 126 EALNSAVSARLLRRMTERNTSGAS 149 S G S Sbjct: 120 AEPKRRPSKLEDDSQDGMPLVGRS 143
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 32.7 bits (74), Expect = 0.031 Identities = 22/124 (17%), Positives = 48/124 (38%), Gaps = 8/124 (6%) Query: 2666 LPDYMVPTHLMLL------ASMPLTANGKLDR-RALPAPGPELNRQHYIAPASELEQQLA 2718 + D+ + H M L + + + LD+ + PA + + E Sbjct: 178 VADFSLEKHQMALEYAAGRCAFTVMTDSLLDQLQNAPADVQKTSANTGKKNVFTCENIRK 237 Query: 2719 AIWCAV-LNVEKVGLNDNFFELGGDSILSIQVVSRARQAGIHFSPRDLFQHQTVQTLAAV 2777 I + E + ++ + G DS+ + +V + R+ G + +L + T++ + Sbjct: 238 QIAELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEWQKL 297 Query: 2778 ATTR 2781 TTR Sbjct: 298 LTTR 301
>adhesinb#Adhesin B signature. Length = 310 Score = 54.1 bits (130), Expect = 2e-10 Identities = 26/119 (21%), Positives = 44/119 (36%), Gaps = 3/119 (2%) Query: 148 WLASNNMGRMADVLAADLVRLAPAAKPKIEANLAAFKQRLLKLSASSEAALA--GADNLS 205 WL N A +A L PA K E NL A+ ++L L ++ + Sbjct: 142 WLNLENGIIYAQNIAKRLSEKDPANKETYEKNLKAYVEKLSALDKEAKEKFNNIPGEKKM 201 Query: 206 VVSLSDRFGYLISGLNLELIDSQ-VLTDEQWTPEALGKLSATLKDNDVALVLDHRQPPE 263 +V+ F Y N+ + T+E+ TP+ + L L+ V + + Sbjct: 202 IVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIKTLVEKLRKTKVPSLFVESSVDD 260
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 166 bits (421), Expect = 2e-51 Identities = 77/309 (24%), Positives = 136/309 (44%), Gaps = 12/309 (3%) Query: 13 KRRPFLRVLLLSLFA-AMLAPASFAADPAKRLRIGITLHPYYSYVSNIVGDKAEVVPLIP 71 K+ L VL LS A ++L++ T NI GDK ++ ++P Sbjct: 2 KKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIVP 61 Query: 72 AGFNPHAYEPRAEDIKRIGSLDVIVLNGV-----GHDDFADRMIAASETPDIKTIEANAD 126 G +PH YEP ED+K+ D+I NG+ G+ F + A +T + + Sbjct: 62 IGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVSDG 121 Query: 127 VPLLAATGVAARGAGKVVNPHTFLSISASIAQVNNIARELGKLDPDNAKTYTTNARAYGK 186 V ++ G +G +PH +L++ I NIA++L DP+N + Y N + Y Sbjct: 122 VDVIYLEGQNEKGKE---DPHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTD 178 Query: 187 RLRQMRADALAKLTKAPNADLRVATVHAAYDYLLREFGLEVTAVVEPAHGIEPSPSQLKK 246 +L ++ ++ K K P + T A+ Y + +G+ + E E +P Q+K Sbjct: 179 KLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEEGTPEQIKT 238 Query: 247 TIDQLRELDVKVIFSEMDFPSTYVDTIQRESGVKLY-PLSHISYGEY--TADKYEKEMAG 303 +++LR+ V +F E + T+ +++ + +Y + S E D Y M Sbjct: 239 LVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTDSIAEQGKEGDSYYSMMKY 298 Query: 304 NLDTVVRAI 312 NLD + + Sbjct: 299 NLDKIAEGL 307
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 30.6 bits (69), Expect = 0.012 Identities = 21/143 (14%), Positives = 45/143 (31%), Gaps = 26/143 (18%) Query: 165 GTQVRKIRLFKDSATVSADEIIGSIARSIQPKTRVLGMTWVQSGSGVKLPIGAIGDLVEE 224 + I++ + D II I +I+ K ++ M+ + + V++ Sbjct: 109 EADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVDIISMSLGGPEDV-----PELHEAVKK 163 Query: 225 HNRNRDDKDRILYVVDGVHGFGVENLDFPDMNCDFYVAGTHKWMFGPRGTGIVCARSEQV 284 ++ IL + G E + Y ++ + V A + Sbjct: 164 AVASQ-----ILVMC----AAGNEGDGDDRTDELGYPGCYNEVI-------SVGAINFDR 207 Query: 285 KDLTPLIPTFSEATNFGTIMTPG 307 FS + N ++ PG Sbjct: 208 H-----ASEFSNSNNEVDLVAPG 225
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 35.4 bits (81), Expect = 4e-04 Identities = 31/175 (17%), Positives = 50/175 (28%), Gaps = 13/175 (7%) Query: 26 EGDAVKRDEMLVDIETDKVVLEVLAEADGVMGAITKEEGAIVLSNEVLGTLNDGATASAA 85 + +RD + V + + V L + G L N + N + Sbjct: 944 DASKAQRDHLNVSLVGNTVDLGAWKYK------LRNVNGRYDLYNPEVEKRNQTVDTTNI 997 Query: 86 PAPAAAPASAPAA----APAAAGEEDPIAAPAARQLAEENGINLASVKGTGKDGRITKED 141 P A P+ A +E P+ PA +E + K K ++D Sbjct: 998 TTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQD 1057 Query: 142 IVAAVEAKKSAPAAAPAAKPVAAAAPVVAAGDRTEKRVPMTRVRATVAKRLVEAQ 196 A E A AK A ++ T+ T VE + Sbjct: 1058 ---ATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109
>PF06580#Sensor histidine kinase Length = 349 Score = 33.3 bits (76), Expect = 0.001 Identities = 24/131 (18%), Positives = 43/131 (32%), Gaps = 29/131 (22%) Query: 222 GDDVQYEGQCKPLRTQPMALRSCLQNLVDNALRYA-------GSARIVIEDSADHVRVSV 274 D +Q+E Q P +Q LV+N +++ G + V + V Sbjct: 237 EDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 275 VDHGPGIAPEFHETVFEPFYRLESSRNRNSGGIGMGMSIAREAARRIGG---QLSLAQTP 331 + G E G G+ RE + + G Q+ L++ Sbjct: 297 ENTGSLALKNTKE------------------STGTGLQNVRERLQMLYGTEAQIKLSEKQ 338 Query: 332 GGGLTAVLDLP 342 G A++ +P Sbjct: 339 GKV-NAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 8e-23 Identities = 36/130 (27%), Positives = 64/130 (49%), Gaps = 1/130 (0%) Query: 2 RALIVDDDVAIRELLCDYLTRFNINARGVTDGSQMRQALTDETFDVVVLDLMLPGEDGLS 61 L+ DDD AIR +L L+R + R ++ + + + + D+VV D+++P E+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LCRWLRST-SDIPILMLTARCEPTDRIIGLELGADDYMAKPFEPRELVARIQTILRRVRD 120 L ++ D+P+L+++A+ I E GA DY+ KPF+ EL+ I L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 ERSDQRTTIR 130 S + Sbjct: 125 RPSKLEDDSQ 134
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 317 bits (814), Expect = 8e-98 Identities = 218/712 (30%), Positives = 315/712 (44%), Gaps = 83/712 (11%) Query: 142 TGSSVNLTNSSSSGALAGTVVTHFSQLGLTGSQLAGTGVDGVG-----------LRLNAG 190 N+T +SGA A V S+L L G + G GV + G Sbjct: 202 VLRDTNVTAVPASGAPAAVSVLGASELTLDGGHITGGRAAGVAAMQGAVVHLQRATIRRG 261 Query: 191 AAQASASSIVGTVNGVAISSEEVYTEASLKLDSTQVVGQTGAAIRIAPLISRLPGSVVAL 250 A A + G V G A+ LD V +G+++ +A I P A+ Sbjct: 262 DAPAGGAVPGGAVPGGAVPGGFGPGGFGPVLDGWYGVDVSGSSVELAQSIVEAPELGAAI 321 Query: 251 DVSN-------GSSLTGGNGNMLEVTGGSSAVMNVSA---------SSLSGNVQVESAS- 293 V G SL+ +GN++E TGG+ +A + G + Sbjct: 322 RVGRGARVTVSGGSLSAPHGNVIE-TGGARRFAPQAAPLSITLQAGAHAQGKALLYRVLP 380 Query: 294 -AVTLNL-DNSSMTGDVLAE--------SGALADVLLDNNSVLTGHLENTRSVAINNGAQ 343 V L L + GD++A S DV L + + TG S++I+N Sbjct: 381 EPVKLTLTGGADAQGDIVATELPSIPGTSIGPLDVALASQARWTGATRAVDSLSIDNAT- 439 Query: 344 WAMIGNGNLAELTLNG-GSVRF---GDAAGFYTLSVANLSGNGTFIMDVDFAAGRTDFLD 399 W M N N+ L L GSV F +A F L+V L+G+G F M+V G +D L Sbjct: 440 WVMTDNSNVGALRLASDGSVDFQQPAEAGRFKVLTVNTLAGSGLFRMNVFADLGLSDKLV 499 Query: 400 ITGSATGSHSLLIGSTGTEP-SADTSLHVVRAAAGDADFSL--VGGAVDLGAWSYDLVKQ 456 + A+G H L + ++G+EP SA+T L V A F+L G VD+G + Y L Sbjct: 500 VMQDASGQHRLWVRNSGSEPASANTLLLVQTPLGSAATFTLANKDGKVDIGTYRYRLAAN 559 Query: 457 GANDWYLDA------------------------------QTRKVSPAAATVVALFNT--- 483 G W L Q +A A NT Sbjct: 560 GNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELSAAANAAVNTGGV 619 Query: 484 --APTVWYGELTSLRTRMGELRHNGGQSGAWMRTYGNKFNVSDASGFGYQQTQQGFSLGA 541 A T+WY E +L R+GELR N GAW R + + + + +G + Q GF LGA Sbjct: 620 GLASTLWYAESNALSKRLGELRLNPDAGGAWGRGFAQRQQLDNRAGRRFDQKVAGFELGA 679 Query: 542 DGKVPMGDGQWLAGVMAGQSSSDLSLDRGASGKVDSYYVGAYSTWLDSDTGYYFDGVLKF 601 D V + G+W G +AG + D G DS +VG Y+T++ +D+G+Y D L+ Sbjct: 680 DHAVAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTDSVHVGGYATYI-ADSGFYLDATLRA 738 Query: 602 NRFNNKARVNLSDGTRTKGDYSNSGVGASLEFGRHIKLDNGYFVEPYSQLAGVVVEGKDY 661 +R N +V SDG KG Y GVGASLE GR +G+F+EP ++LA G Y Sbjct: 739 SRLENDFKVAGSDGYAVKGKYRTHGVGASLEAGRRFTHADGWFLEPQAELAVFRAGGGAY 798 Query: 662 ELDNGMRAENDLTRSLVGKLGATTGRNFDLGQGRTVQPYVRTAWVHEFAKNNEVQVNDNV 721 NG+R ++ S++G+LG G+ +L GR VQPY++ + + EF V N Sbjct: 799 RAANGLRVRDEGGSSVLGRLGLEVGKRIELAGGRQVQPYIKASVLQEFDGAGTVHTNGIA 858 Query: 722 FNNDLSGSRGELGIGIAASLSERFQVHADFEHSNGDKVEQPWGASVGIRYSW 773 +L G+R ELG+G+AA+L ++A +E+S G K+ PW G RYSW Sbjct: 859 HRTELRGTRAELGLGMAAALGRGHSLYASYEYSKGPKLAMPWTFHAGYRYSW 910
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 748 bits (1933), Expect = 0.0 Identities = 269/870 (30%), Positives = 432/870 (49%), Gaps = 55/870 (6%) Query: 9 LIPVRLRFMQLLIVCGSGALPLELIQAADLVNFQSGFLRQGQGYDIDAANKALNNLAEVE 68 + F++L + C A + ++ + F FL D L+ + Sbjct: 20 KHRLAGFFVRLFVACAFAA---QAPLSSAELYFNPRFLADDPQAVAD-----LSRFENGQ 71 Query: 69 DLAPGNHWVEIHINTRYFGQRELRFDADPQGNGLLPCLSKELLEQMGVRIESLAEQTLLQ 128 +L PG + V+I++N Y R++ F+ G++PCL++ L MG+ S++ LL Sbjct: 72 ELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLA 131 Query: 129 AS-CVDLSRLIPQATTKLDGGRLQLSISIPQIAMRLDAIGRVDPALWDYGINAAFVSYQA 187 CV L+ +I AT +LD G+ +L+++IPQ M A G + P LWD GINA ++Y Sbjct: 132 DDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNF 191 Query: 188 SAQQTTRTDTGTGNSANLYLNSGINLGAWRLRSNQS-----VRHDEEGRREWTRAYAYAQ 242 S G + A L L SG+N+GAWRLR N + + +W + + Sbjct: 192 SGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLE 251 Query: 243 RDLPGTHANLTIGETSTDSNVFRSVPIKGALIKTDQEMLPDTAQGYAPVIRGVAQSRAKL 302 RD+ + LT+G+ T ++F + +GA + +D MLPD+ +G+APVI G+A+ A++ Sbjct: 252 RDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQV 311 Query: 303 EVLQNGYPIYSTYVSAGPYEIDDL-AATGSGELEVVLTEADGQVRRFSQPYATIGNLLRE 361 + QNGY IY++ V GP+ I+D+ AA SG+L+V + EADG + F+ PY+++ L RE Sbjct: 312 TIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQRE 371 Query: 362 GVWKYSTALGRY-NGASAIEQPWIWQSTLAIGTGWNATLYGGLMASDMYRATALGISRDL 420 G +YS G Y +G + E+P +QSTL G T+YGG +D YRA GI +++ Sbjct: 372 GHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNM 431 Query: 421 GALGAVALDATQSDADIDRAGTTSVQGMSYALKYGKMFT-TNTNLRFAGYRYSTQGYRDF 479 GALGA+++D TQ+++ + G S Y K + TN++ GYRYST GY +F Sbjct: 432 GALGALSVDMTQANSTLPDDSQH--DGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNF 489 Query: 480 DETMRQRDNNR-------------------PFTGSRRSRLEASVHQKVGSRSSVSLTMSR 520 +T R N ++R +L+ +V Q++G S++ L+ S Sbjct: 490 ADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSH 549 Query: 521 QNYWGSAAEQQQYQFNFNTQHAGVTYNLYASQSLTDTRNQKNDRQLGLSISLPLDIGHSS 580 Q YWG++ +Q+Q NT + + L S + + D+ L L++++P S Sbjct: 550 QTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKG-RDQMLALNVNIPFSHWLRS 608 Query: 581 SAAFDLQN----------SGDHYSQRASLSGSL-DDNRLNYRTSLSNDDGR----QQSAG 625 + ++ + A + G+L +DN L+Y G + Sbjct: 609 DSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGY 668 Query: 626 LAVGYQAPFASFGAGLTQGNDYRSTSINVSGALLMHAGGIEPGPSLGDTIALIEVPDTPG 685 + Y+ + + G + +D + VSG +L HA G+ G L DT+ L++ P Sbjct: 669 ATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKD 728 Query: 686 VGVQNAIGVETNSRGYALVPYLRPYRYNHIELQTDQLGPEIEIDNGSARVVPARGAVVKT 745 V+N GV T+ RGYA++PY YR N + L T+ L +++DN A VVP RGA+V+ Sbjct: 729 AKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRA 788 Query: 746 TFAARTVTRLVITALTDSGKPLPFGAQVSDAEGNIMGIAGQGGLILLSTGMQAQTLDVSW 805 F AR +L++T LT + KPLPFGA V+ GI G + LS A + V W Sbjct: 789 EFKARVGIKLLMT-LTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKW 847 Query: 806 GEQTESRCRLHIDPTNMPLTKGYRIQSLTC 835 GE+ + C + + S C Sbjct: 848 GEEENAHCVANYQLPPESQQQLLTQLSAEC 877
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 31.4 bits (71), Expect = 0.021 Identities = 9/31 (29%), Positives = 13/31 (41%) Query: 897 ETGKLVISLHRTYPVVFIPASPPPPPPTPPN 927 + KL+IS YP + + P P P Sbjct: 44 LSFKLLISSSSNYPRIHLTDLTKPNPIKAPM 74
>PF06580#Sensor histidine kinase Length = 349 Score = 30.6 bits (69), Expect = 0.028 Identities = 25/189 (13%), Positives = 63/189 (33%), Gaps = 40/189 (21%) Query: 699 RDEAERLDRYIQNLLDMTRLGHGALKLARDWVSPADIVGSALNRLRAVLT--------PL 750 ++ + + +L ++ R +L+ + + L + + L L Sbjct: 187 LEDPTKAREMLTSLSELMRY---SLRYSNARQVS---LADELTVVDSYLQLASIQFEDRL 240 Query: 751 QVSTQVTGDLPLLYVHAALIEQALVNVLENAAR--FSPL--GGRLQVTAGVVDSELFFSV 806 Q Q+ + + V ++ Q LV EN + + L GG++ + + + V Sbjct: 241 QFENQINPAIMDVQV-PPMLVQTLV---ENGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 807 SDEGPGIPEDERAKIFDMFYTAARGDRGGQGTGLGLA-ICQGMIGAHGGRLTVEEGIDGL 865 + G ++ + + TG GL + + + +G ++ Sbjct: 297 ENTGSLALKNTK-----------------ESTGTGLQNVRERLQMLYGTEAQIKLSEKQG 339 Query: 866 GTRITLFLP 874 + +P Sbjct: 340 KVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.1 bits (234), Expect = 2e-24 Identities = 43/139 (30%), Positives = 65/139 (46%), Gaps = 2/139 (1%) Query: 3 QTATILVIDDEPQIRKFLRISLVSQGYKVLEAATGTEGLTQAALNKPDLLVLDLGLPDMD 62 ATILV DD+ IR L +L GY V + A DL+V D+ +PD + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GQQVLSEFREWSA-VPVLVLSVRASEAQKVQALDAGANDYVTKPFGIQEFLARV-RALLR 120 +L ++ +PVLV+S + + ++A + GA DY+ KPF + E + + RAL Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 121 QVSGSDKPESALRFGPLTV 139 K E + G V Sbjct: 122 PKRRPSKLEDDSQDGMPLV 140
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.010 Identities = 10/43 (23%), Positives = 20/43 (46%) Query: 103 DEINRATPKSQSALLEAMEEGQVSIEGATRLLPDPFFVIATQN 145 DEI +Q+ LL +++G+ + G + ++A N Sbjct: 238 DEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATN 280
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 29.5 bits (66), Expect = 0.015 Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 8/70 (11%) Query: 165 DRHDLRLLIKRVRYAAEAYPELSHQPKNMQARLKSAQGE-LGDWHDHLQWLAQAEEQADL 223 + DLR I V E+S+Q + L +Q + L + +WL+Q + + L Sbjct: 521 NGQDLRTGILTVD-------EISNQSTTLNKLLGGSQCQPLNKAQEVQKWLSQNNKSSYL 573 Query: 224 APCVPGWQIG 233 C +G Sbjct: 574 TQCKMDKSLG 583
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 26.7 bits (59), Expect = 0.010 Identities = 13/44 (29%), Positives = 24/44 (54%), Gaps = 3/44 (6%) Query: 31 LIAVPLFILASLLVLNGMFSESLSSMAIGVIGLAAALGFQRKDA 74 IAVP+ +L + +L F S++++ + G+ A+G DA Sbjct: 369 TIAVPVVLLGTFAILA-AFGYSINTLTMF--GMVLAIGLLVDDA 409
>PF06917#Periplasmic pectate lyase Length = 555 Score = 27.2 bits (60), Expect = 0.025 Identities = 10/31 (32%), Positives = 14/31 (45%), Gaps = 7/31 (22%) Query: 99 IFTVHIHNGFFMANNGYEYA-------LALL 122 +F H H G F+ + + Y LALL Sbjct: 476 LFKRHYHRGLFVESAQHRYFRIDNPIALALL 506
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 307 bits (787), Expect = 2e-98 Identities = 123/346 (35%), Positives = 180/346 (52%), Gaps = 27/346 (7%) Query: 4 RELLRRPSEPDVLAVGASAAFVRVIHQVDQIAPTGHTVLITGPSGAGKEVIAQRLHRLGV 63 +L + L VG SAA + + ++ T T++ITG SG GKE++A+ LH G Sbjct: 127 SKLEDDSQDGMPL-VGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGK 185 Query: 64 NPLHPFVDINCAALPAHLIEAELFCHSRGAFTGAVHTRVGHFEAAGSGTLFLDEIGELPL 123 PFV IN AA+P LIE+ELF H +GAFTGA G FE A GTLFLDEIG++P+ Sbjct: 186 RRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPM 245 Query: 124 ALQPVLLRVLETRSFRPLGSNLVRAFQGRIVAATHRNLREMVDQGLFREDLYYRLAVFEI 183 Q LLRVL+ + +G RIVAAT+++L++ ++QGLFREDLYYRL V + Sbjct: 246 DAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPL 305 Query: 184 VLPGLDQRPEDVVLLAHYFASRLSR----PLSFTPDADVLLARQRWPGHARQLRTLIERL 239 LP L R ED+ L +F + + F +A L+ WPG+ R+L L+ RL Sbjct: 306 RLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRL 365 Query: 240 SVMADSTLISAIVLQPF---------LEVSRSQERLPPPRDIVDDLMRLPG--------- 281 + + +I+ +++ +E + ++ V++ MR Sbjct: 366 TALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPP 425 Query: 282 ----KDKLAAAEQLLIDRALHLSSGNKSAAAKLLGVGRKVIERRLR 323 LA E LI AL + GN+ AA LLG+ R + +++R Sbjct: 426 SGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIR 471
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 28.9 bits (64), Expect = 0.045 Identities = 14/29 (48%), Positives = 18/29 (62%), Gaps = 2/29 (6%) Query: 431 NTVRAIAGFSRDSNGNTWAVVAILNDPRP 459 N V+ +A F RDS GNT V ++ PRP Sbjct: 287 NPVQVVATFGRDSQGNTTVDVQVI--PRP 313
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.3 bits (180), Expect = 5e-16 Identities = 41/161 (25%), Positives = 62/161 (38%), Gaps = 10/161 (6%) Query: 239 RILIVDDHPANRLLLCQQLGFLGHHCEMAENGAQGLERWKADAFDLVVADCNMPIMNGYD 298 IL+ DD A R +L Q L G+ + N A A DLVV D MP N +D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 299 MTLALRTHESVTEQPRCPVWGFTANAQPDEIERCRAAGMDDCLFKPISLS-MLSERLTAI 357 + ++ +P PV +A + G D L KP L+ ++ A+ Sbjct: 65 LLPRIKKA-----RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 358 SPLARAHPPFSLD--SISSLTGNRPEMVE--RLITQLQHSN 394 + R D L G M E R++ +L ++ Sbjct: 120 AEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTD 160
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.9 bits (101), Expect = 3e-06 Identities = 26/200 (13%), Positives = 69/200 (34%), Gaps = 25/200 (12%) Query: 28 RVAASKLAQQLAELKAAHQAEHQQLLNDAALAHQREQQMLHEQ-EEHQRELALLSEDIGR 86 R + +L +L + N + R ++ EQ Q + ++ Sbjct: 152 RYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNL-- 209 Query: 87 HRDVERQLSIQLGELKASLDAEKQRMSDKVEQLTEVNTLAENRSLESNKLRMQLGELRVQ 146 + + + A ++ + + +L + ++L +++ + + Sbjct: 210 -----DKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAV---------- 254 Query: 147 VGQGQEQTRQLEELKQILAQHQMRLEAAQLQLQKQGEQLGQSTE--QANQLLELKAAHAN 204 EQ + E L ++ +LE + ++ E+ T+ + L +L+ N Sbjct: 255 ----LEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDN 310 Query: 205 -SQTRIEKAEEEFKKQREQL 223 +E A+ E ++Q + Sbjct: 311 IGLLTLELAKNEERQQASVI 330 Score = 37.9 bits (88), Expect = 1e-04 Identities = 33/209 (15%), Positives = 67/209 (32%), Gaps = 22/209 (10%) Query: 93 QLSIQLGELKASLDAEKQRMSDKVEQLTEVNTLAENRSLESNKL---------RMQLGEL 143 + ++L L A D K + S +L + +RS+E NKL Q Sbjct: 122 DVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSE 181 Query: 144 RVQVGQGQEQTRQLEELKQILAQHQMRLEAAQLQLQKQGEQLGQSTEQANQLLELKAAHA 203 + Q + Q ++ L+ + + ++ + + Sbjct: 182 EEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE-------- 233 Query: 204 NSQTRIEKAEEEFKKQREQLGQAAEQKEQLDVLRGTLVQRDKELGVVRDELSLAKQSLAE 263 ++R++ KQ EQ+ + L +L + E+ AK+ Sbjct: 234 --KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQ- 290 Query: 264 VNMRHARDQHSAAEKLQLLEDNKVQLKQE 292 + ++ +KL+ DN L E Sbjct: 291 --LVTQLFKNEILDKLRQTTDNIGLLTLE 317 Score = 31.7 bits (72), Expect = 0.009 Identities = 27/167 (16%), Positives = 55/167 (32%), Gaps = 36/167 (21%) Query: 32 SKLAQQLAELKAAHQAEHQQLLNDAALAHQREQQMLHEQEEHQRELALLSE-DIGRHRDV 90 S Q + + + + L A ++ E E+ +LL + I +H Sbjct: 196 STWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHA-- 253 Query: 91 ERQLSIQLGELKASLDAEKQRMSDKVEQLTEVNTLAENRSLESNKLRMQLGELRVQVGQG 150 L+ E + + N L +S QL ++ ++ Sbjct: 254 -------------VLEQENKYVEAV-------NELRVYKS--------QLEQIESEILSA 285 Query: 151 QEQTRQLEELKQ-----ILAQHQMRLEAAQLQLQKQGEQLGQSTEQA 192 +E+ + + +L + L Q + L+L K E+ S +A Sbjct: 286 KEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRA 332
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.006 Identities = 13/37 (35%), Positives = 18/37 (48%) Query: 26 VLRGLSFSVRSGECLMLSGQSGAGKSTLLRTLYGNYL 62 V R + + ++L G G GKSTL+ TL G Sbjct: 585 VARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGLDF 621
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1134 bits (2936), Expect = 0.0 Identities = 511/1030 (49%), Positives = 707/1030 (68%), Gaps = 8/1030 (0%) Query: 1 MSLFFIKRPNFAWVLALFILLAGLMALPALPVAQYPNVAPPQITITATYPGASAKVLVDS 60 M+ FFI+RP FAWVLA+ +++AG +A+ LPVAQYP +APP ++++A YPGA A+ + D+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTSVIEEELNGAKGMLYYESTSNSTGSAEINVTFVPGTNPDMAQVEVQNRIKKAEARLPQ 120 VT VIE+ +NG ++Y STS+S GS I +TF GT+PD+AQV+VQN+++ A LPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 TVLSQGLQVEQASSGFLMIYTLSYTGDSANKDTVALADYAARNVNNEISRVNGVGRLQFF 180 V QG+ VE++SS +LM+ +D ++DY A NV + +SR+NGVG +Q F Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDD--ISDYVASNVKDTLSRLNGVGDVQLF 178 Query: 181 AAEAAMRVWIDPQKLVGFGLSIDDVNAAVRAQNVQVPAGSFGSSPGSSLQELTATLAVKG 240 A+ AMR+W+D L + L+ DV ++ QN Q+ AG G +P Q+L A++ + Sbjct: 179 GAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 241 TLDNPEEFGRIVLRANEDGSTVHLSDVARVAIGSQDYSFESRLNGKRAVAGAVQLSPGAN 300 NPEEFG++ LR N DGS V L DVARV +G ++Y+ +R+NGK A ++L+ GAN Sbjct: 239 RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGAN 298 Query: 301 AIETVKAVKQRLTELSVNFPEGVEFSVPYDTSRFVDVAIDKVIYTLIEAMVLVFLVMFLF 360 A++T KA+K +L EL FP+G++ PYDT+ FV ++I +V+ TL EA++LVFLVM+LF Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 361 LQNIRYTLIPTIVVPVCLAGTLAIMYLLGFSVNMMTMFGMVLAIGILVDDAIVVVENVER 420 LQN+R TLIPTI VPV L GT AI+ G+S+N +TMFGMVLAIG+LVDDAIVVVENVER Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 421 IMAEEGLSPAAATVKAMQQVSGAIFGITLVLAAVFLPLAFMGGSVGVIYQQFSLSLAVSI 480 +M E+ L P AT K+M Q+ GA+ GI +VL+AVF+P+AF GGS G IY+QFS+++ ++ Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 481 LFSGFLALTFTPALCATLLKPIPAGHHE-KRGFFGGFNRLFGKFTDRYERVSSSMIKRAG 539 S +AL TPALCATLLKP+ A HHE K GFFG FN F + Y ++ G Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTG 538 Query: 540 RYMLLYVGIVGLLGFFYLRLPESFVPVEDQGYLIIDVQLPPGATRARTDATA-QLLEIYM 598 RY+L+Y IV + +LRLP SF+P EDQG + +QLP GAT+ RT Q+ + Y+ Sbjct: 539 RYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYL 598 Query: 599 LSREAT-GAVTMLLGFSFSGMGENAGLAFPTLKDWSVR-GDGQSAGEEAAAFNQHFAGLS 656 + +A +V + GFSFSG +NAG+AF +LK W R GD SA + Sbjct: 599 KNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658 Query: 657 DGTVMAVTPPPIDGLGTSGGFALRLQDRAGLGREALLAARNELLGKANGNP-KILYAMME 715 DG V+ P I LGT+ GF L D+AGLG +AL ARN+LLG A +P ++ Sbjct: 659 DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 716 GLAEAPQLRLNIDREKARALGVSFESISNALSTAFGSSVISDFANAGRQQRVVVQAEQSS 775 GL + Q +L +D+EKA+ALGVS I+ +STA G + ++DF + GR +++ VQA+ Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 776 RMTPESVLKLYVPNSSGTLVPLSAFVSTHWEEGPVQIARYNGYPTFRIAGDAPPGVSTGE 835 RM PE V KLYV +++G +VP SAF ++HW G ++ RYNG P+ I G+A PG S+G+ Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 836 AMAEIERIVSRLPPGIGYEWTGLSYQEKVASGQATGLFALALLVVFLLLVALYESWAIPL 895 AMA +E + S+LP GIGY+WTG+SYQE+++ QA L A++ +VVFL L ALYESW+IP+ Sbjct: 839 AMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPV 898 Query: 896 VVMLIVPVGALGSVLAVTAVGMPNDVYFKVGLITIIGLAAKNAILIVEFAKELWD-QGHS 954 VML+VP+G +G +LA T NDVYF VGL+T IGL+AKNAILIVEFAK+L + +G Sbjct: 899 SVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKG 958 Query: 955 LRDAALQAARLRFRPIVMTSLAFILGVVPLTLATGAGAASQRAIGTGVIGGMLSATLLGV 1014 + +A L A R+R RPI+MTSLAFILGV+PL ++ GAG+ +Q A+G GV+GGM+SATLL + Sbjct: 959 VVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAI 1018 Query: 1015 VLVPIFFVWV 1024 VP+FFV + Sbjct: 1019 FFVPVFFVVI 1028 Score = 85.7 bits (212), Expect = 5e-19 Identities = 66/329 (20%), Positives = 126/329 (38%), Gaps = 17/329 (5%) Query: 722 QLRLNIDREKARALGVSFESISNALSTA---FGSSVISDFANAGRQQRVVVQAEQSSRMT 778 +R+ +D + ++ + N L + + QQ Q+ Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 779 PESVLKLYVP-NSSGTLVPLS--AFVSTHWEEGPVQIARYNGYPTFRIAGDAPPGVSTGE 835 PE K+ + NS G++V L A V E IAR NG P + G + + Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGEN-YNVIARINGKPAAGLGIKLATGANALD 301 Query: 836 A----MAEIERIVSRLPPGIGYEW---TGLSYQEKVASGQATGLFALALLVVFLLLVALY 888 A++ + P G+ + T Q + T A+ L VFL++ Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIML--VFLVMYLFL 359 Query: 889 ESWAIPLVVMLIVPVGALGSVLAVTAVGMPNDVYFKVGLITIIGLAAKNAILIVE-FAKE 947 ++ L+ + VPV LG+ + A G + G++ IGL +AI++VE + Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 948 LWDQGHSLRDAALQAARLRFRPIVMTSLAFILGVVPLTLATGAGAASQRAIGTGVIGGML 1007 + + ++A ++ +V ++ +P+ G+ A R ++ M Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 1008 SATLLGVVLVPIFFVWVLSVLRRKPHETK 1036 + L+ ++L P +L + + HE K Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENK 508
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.4 bits (97), Expect = 5e-06 Identities = 17/100 (17%), Positives = 41/100 (41%), Gaps = 3/100 (3%) Query: 103 KAALSKAQGDLARTEATLFETQATVKRYESLVEIEAVSRQTFDTARSALQNAAAAKKSAQ 162 + +A +L ++ L + ++ + + E + V++ + L+ Sbjct: 258 ENKYVEAVNELRVYKSQLEQIESEILSAKE--EYQLVTQLFKNEILDKLRQTTDNIGLLT 315 Query: 163 ADVETARLDLGYATVRAPISGRIGRAMV-TEGALVGQGET 201 ++ + +RAP+S ++ + V TEG +V ET Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET 355 Score = 32.5 bits (74), Expect = 0.003 Identities = 19/113 (16%), Positives = 34/113 (30%), Gaps = 1/113 (0%) Query: 58 PGRIEPV-RVAQVRARVAGIVLTRNFEEGADVRAGAVLFQIDPAPFKAALSKAQGDLART 116 G++ R +++ IV +EG VR G VL ++ +A K Q L + Sbjct: 87 NGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQA 146 Query: 117 EATLFETQATVKRYESLVEIEAVSRQTFDTARSALQNAAAAKKSAQADVETAR 169 Q + E E + + + T + Sbjct: 147 RLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQ 199
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 32.3 bits (73), Expect = 7e-04 Identities = 16/144 (11%), Positives = 50/144 (34%), Gaps = 15/144 (10%) Query: 24 TFKDIAEAAGVSKATLNRFCGTRANLIEILLIHASELMNKMIADADLQ-----NAPPLEA 78 + +IA+AAGV++ + +++L + + + ++ + + + E Sbjct: 33 SLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREI 92 Query: 79 LQRLIDNHLTHREMLVFLVFQWRPDTM------DESCGGLRWLPYSDALDAFFLRGQREG 132 L ++++ +T + + + + L D ++ Sbjct: 93 LIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAK 152 Query: 133 LFRIDISAPVLTETFASLLFGLVD 156 + A ++T A ++ G + Sbjct: 153 MLP----ADLMTRRAAIIMRGYIS 172
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 61.6 bits (149), Expect = 9e-12 Identities = 28/87 (32%), Positives = 51/87 (58%) Query: 8 ASTARGTPPQAFDPALLGEDIARQLRLSPEQLADDANLLKLGMDSMHLMAWLNRFRRLGF 67 ++A F + + IA L+ +PE + D +LL G+DS+ +M + ++RR G Sbjct: 219 KTSANTGKKNVFTCENIRKQIAELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGA 278 Query: 68 KVTLSDLYDQPTLQGWQQLLSSAPVQV 94 +VT +L ++PT++ WQ+LL++ QV Sbjct: 279 EVTFVELAERPTIEEWQKLLTTRSQQV 305
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 43.3 bits (102), Expect = 1e-06 Identities = 29/161 (18%), Positives = 61/161 (37%), Gaps = 21/161 (13%) Query: 52 FFPTGSELTSYLLALATFGVGFFMRPVGGIVLGIYSDKRGRKAALSLTILLMALGTLIIG 111 + Y + LA + M+ VLG SD+ GR+ L +++ A+ I+ Sbjct: 35 LVHSNDVTAHYGILLALYA---LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMA 91 Query: 112 LTPSFAQIGYLAPVLIVLARLLQGFSAGGEMGSATAFLTEHAPAGKKAFYSSWIQASIGV 171 P ++ + R++ G + G A A++ + ++A + ++ A G Sbjct: 92 TAPFLW--------VLYIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGF 142 Query: 172 AVLLGSALGTVLSSYLTQAQLESWGWRVPFLIGTLIGPVGF 212 ++ G LG ++ + PF + + F Sbjct: 143 GMVAGPVLGGLMGGF---------SPHAPFFAAAALNGLNF 174
>PF07328#T-DNA border endonuclease VirD1 Length = 144 Score = 32.7 bits (74), Expect = 0.001 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%) Query: 112 WYEAQFGADGWAALDKI--PRLQWAEYLRWYRKALALDVRNEHRVSRVAPR-TDGLVELD 168 W EA+ GA G A +DK+ ++ AE + + L + N +R R+A R G VE D Sbjct: 6 WREAEDGAAGPARVDKVISVKMTEAELAEFDAQIAELGL-NRNRALRIAARRIGGFVEND 64 Query: 169 IMTPGQTRFMLARHVVLAT 187 T R M +AT Sbjct: 65 AKTVELLRDMSRAIAGVAT 83
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.8 bits (124), Expect = 2e-09 Identities = 36/227 (15%), Positives = 78/227 (34%), Gaps = 26/227 (11%) Query: 94 LVLRNTLRQAEVDEEKLQADRHSAKAQMKQAERLYKRYKDLQTDQSVSRQDFENAESDYE 153 + ++ + + E + + K+Q++Q E + + + Q F+N D + Sbjct: 248 AIAKHAVLEQENKYVEAVNELRVYKSQLEQIES---EILSAKEEYQLVTQLFKNEILD-K 303 Query: 154 MQQANVRALDAQIKSAQVQIDTAKVNLGYTRIIAPIDGDVVGV-VTQEGQTVIAQQLAPI 212 ++Q I +++ + + I AP+ V + V EG V + + Sbjct: 304 LRQTT-----DNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE--TL 356 Query: 213 LLKLADLDTMTIKAQVSEADVIHIGAGQEVYFTILGEEKRYYAKLRGTEPAPQDYLETES 272 ++ + + DT+ + A V D+ I GQ + Y L G ++ + Sbjct: 357 MVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGK-------VKNIN 409 Query: 273 SGGASRQNSAVFYNALFEVP------NLDH-RLRIAMTAQVRIVLGT 312 Q + +N + + + L M I G Sbjct: 410 LDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGM 456 Score = 47.5 bits (113), Expect = 6e-08 Identities = 21/159 (13%), Positives = 55/159 (34%), Gaps = 29/159 (18%) Query: 45 IENAVLATGVLEGIKQV-DVGAQVSGQLKSLKVKLGDKVKKGQWLAEIDPLV-------L 96 +E A G L + ++ + +K + VK G+ V+KG L ++ L Sbjct: 80 VEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKT 139 Query: 97 RNTLRQAEVDEEKLQADRHS-------------------AKAQMKQAER--LYKRYKDLQ 135 +++L QA +++ + Q S + + +++ Q Sbjct: 140 QSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQ 199 Query: 136 TDQSVSRQDFENAESDYEMQQANVRALDAQIKSAQVQID 174 + + + ++ A + + + + ++D Sbjct: 200 NQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLD 238
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 31.0 bits (70), Expect = 0.008 Identities = 22/89 (24%), Positives = 34/89 (38%), Gaps = 12/89 (13%) Query: 321 EDSYAGVMQ------AIDKVDWSPFGAR---YVVLITDAGALDGDDKLSGTGLNAEQVRI 371 E YAG M+ +++ +D SP G R Y+ LI D + +V Sbjct: 56 EHLYAGFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKVEN 115 Query: 372 EASNPGVAIY---TLHLKTAAGAKDHAKA 397 + P + Y T + + AK AK Sbjct: 116 QNKIPELNEYQCGTAAMHSLDEAKQIAKN 144
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 28.3 bits (63), Expect = 0.017 Identities = 13/115 (11%), Positives = 34/115 (29%), Gaps = 11/115 (9%) Query: 49 QVRQREQALTAARAENASFRDVYDALQAQQQSTSKSLAEQQKQQAALD---GSMSKLLSQ 105 + + +L AR E ++ + +++ + K E Q + + S + Q Sbjct: 135 DTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQ 194 Query: 106 LKARHANKAQAQQQIADLEKQMAAKKQVTASTDPAVIEARKQELKALQQKVSRLQ 160 K Q + + + A I + + + ++ Sbjct: 195 FSTWQNQKYQKELNLDKKRAERLTVL--------ARINRYENLSRVEKSRLDDFS 241 Score = 26.7 bits (59), Expect = 0.044 Identities = 18/129 (13%), Positives = 40/129 (31%), Gaps = 20/129 (15%) Query: 46 YSDQVRQREQALTAARAENASFRDVYDALQAQQQSTSKSLA-----------------EQ 88 + +Q Q+E L RAE + + + + L EQ Sbjct: 198 WQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQ 257 Query: 89 QKQQAALDGSMSKLLSQLKARHANKAQAQQQIADLE---KQMAAKKQVTASTDPAVIEAR 145 + + + SQL+ + A+++ + K K + + ++ Sbjct: 258 ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLE 317 Query: 146 KQELKALQQ 154 + + QQ Sbjct: 318 LAKNEERQQ 326
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.0 bits (70), Expect = 0.012 Identities = 12/34 (35%), Positives = 20/34 (58%), Gaps = 1/34 (2%) Query: 25 QAVRNVSFQVASGE-TVAIVGESGSGKSTLANAI 57 Q + V ++ + T+ I GESG+GK +A A+ Sbjct: 147 QEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.1 bits (73), Expect = 0.007 Identities = 28/157 (17%), Positives = 49/157 (31%), Gaps = 22/157 (14%) Query: 483 AEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQKSTTEIEALIQALQHGTGAA 542 Q ++ RA V + ++ + ++ L A Sbjct: 197 TWQNQKYQKELNLDKKRAERLT-----VLARINRYENLSRVEKSRLDDFSSLLHKQAIAK 251 Query: 543 SELMDASRQRTEGTVELARQAEQSLVEITRSIVTIEQMSQQISAAAEEQSAVTDEINRSV 602 +++ + E EL Q +EQ+ +I +A EE VT Sbjct: 252 HAVLEQENKYVEAVNELRVYKSQ-----------LEQIESEILSAKEEYQLVTQLFKN-- 298 Query: 603 ISVRDIADQSATATEQSAASTVELARLGSNLQGMVAR 639 +I D+ T+ T+ELA+ Q V R Sbjct: 299 ----EILDKLRQTTDNIGLLTLELAKNEERQQASVIR 331
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 57.1 bits (138), Expect = 6e-11 Identities = 18/102 (17%), Positives = 46/102 (45%) Query: 66 EVRPRVSGQIDQVAFTDGSVVKKGDLLFQIDPRPFQSEVRRLEAQLQQARAVASRSDSEA 125 E++P + + ++ +G V+KGD+L ++ +++ + ++ L QAR +R + Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 126 QRGERLRSNNAISAELADSRSTSAQEAKAGVAAIQAQLDLAR 167 + E + + ++ S +E + I+ Q + Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQ 199 Score = 35.6 bits (82), Expect = 4e-04 Identities = 19/113 (16%), Positives = 43/113 (38%), Gaps = 13/113 (11%) Query: 101 QSEVRRLEAQLQQARAVASRSDSE-AQRGERLRSNNAISAELADSRSTSAQEAKAGVAAI 159 +E+R ++QL+Q + + E + ++ I +L + + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNE--ILDKLRQTTDNIGL--------L 314 Query: 160 QAQLDLARLNLSFTRVTAPIAGRVSRAEI-TAGNIVTADVTALTSVVSTDKVY 211 +L + + AP++ +V + ++ T G +VT L +V D Sbjct: 315 TLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA-ETLMVIVPEDDTL 366
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1091 bits (2822), Expect = 0.0 Identities = 425/1040 (40%), Positives = 644/1040 (61%), Gaps = 17/1040 (1%) Query: 4 SKFFISRPIFAAVLSLLILIAGAISLFQLPISEYPEVVPPTVVVRASFPGANPKVIGETV 63 + FFI RPIFA VL++++++AGA+++ QLP+++YP + PP V V A++PGA+ + + +TV Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 64 ASPLEQAITGVEGMLYMSSQATADGKLTLTITFALGTELDNAQVQVQNRVTRTEPKLPEE 123 +EQ + G++ ++YMSS + + G +T+T+TF GT+ D AQVQVQN++ P LP+E Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 124 VTRIGITVDKASPDLTMVVHLTSPDQRYDMLYLSNYAVLNIKDELARLGGVGDVQLFGMG 183 V + GI+V+K+S MV S + +S+Y N+KD L+RL GVGDVQLFG Sbjct: 122 VQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG-A 180 Query: 184 DYSLRVWLDPNKTASRNLTATDVVNAIREQNRQVAAGQLGSPPSPNATSFQMSINTQGRL 243 Y++R+WLD + LT DV+N ++ QN Q+AAGQLG P+ SI Q R Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 244 VSEEEFENVVVRAGPDGEITRLKDVARIELGSSQYALRSLLNNQPAVAMPIFQRPGSNAI 303 + EEF V +R DG + RLKDVAR+ELG Y + + +N +PA + I G+NA+ Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 304 DISNDVRARMAELKKGFPEGMDYSIVYDPTIFVRGSIEAVIHTLFEALILVVLVVVLFLQ 363 D + ++A++AEL+ FP+GM YD T FV+ SI V+ TLFEA++LV LV+ LFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 364 TWRASIIPLVAVPVSLIGTFAVMHMFGFSLNALSLFGLVLAIGIVVDDAIVVVENVER-N 422 RA++IP +AVPV L+GTFA++ FG+S+N L++FG+VLAIG++VDDAIVVVENVER Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 423 IELGLEPVEATHKAMAEVTGPIIATALVLCAVFVPAAFISGLTGQFYKQFALTIAISTVI 482 +E L P EAT K+M+++ G ++ A+VL AVF+P AF G TG Y+QF++TI + + Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 483 SAFNSLTLSPALAAVLLKAHDAPKDRFSRFLDKILGGWLFRPFNRFFEKASHGYVGTVAR 542 S +L L+PAL A LLK A F FN F+ + + Y +V + Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKG--------GFFGWFNTTFDHSVNHYTNSVGK 532 Query: 543 VIRSSGIALLVYAGLMVLTWLGFASTPTGFVPSQDKQYLVAFAQLPDAASLDRTEDVIKR 602 ++ S+G LL+YA ++ + F P+ F+P +D+ + QLP A+ +RT+ V+ + Sbjct: 533 ILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQ 592 Query: 603 MSELALK--QPGVENAIAFPGLSINGFTNSPNNGVVFVALKPFDERKDPSLSANAIAGAL 660 +++ LK + VE+ G S +G + N G+ FV+LKP++ER SA A+ Sbjct: 593 VTDYYLKNEKANVESVFTVNGFSFSG--QAQNAGMAFVSLKPWEERNGDENSAEAVIHRA 650 Query: 661 NGQFASIQEAYMAIFPPPPVQGLGTIGGFRLQIEDRGNLGYDELYKETQNIITKSRSVP- 719 + I++ ++ F P + LGT GF ++ D+ LG+D L + ++ + P Sbjct: 651 KMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPA 710 Query: 720 ELAGLFTSYTVNVPQVDAAIDREKAKTHGVAVSDIFDTLQVYLGSLYANDFNRFGRTYQV 779 L + + + Q +D+EKA+ GV++SDI T+ LG Y NDF GR ++ Sbjct: 711 SLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKL 770 Query: 780 NVQAEQQFRQDADQIGQLKVRNNLGEMIPLATFVKVSDTAGPDRVMHYNGFITAEINGAA 839 VQA+ +FR + + +L VR+ GEM+P + F G R+ YNG + EI G A Sbjct: 771 YVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEA 830 Query: 840 APGFSSGQAQTAVEKLLREELPNGMVYEWTDLTYQQILSGNTALFVFPLCVLLAFLVLAA 899 APG SSG A +E L +LP G+ Y+WT ++YQ+ LSGN A + + ++ FL LAA Sbjct: 831 APGTSSGDAMALMENLA-SKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAA 889 Query: 900 QYESWSLPLAVILIVPMTLLSAIAGVIIAGSDNNIFTQIGLIVLVGLACKNAILIVEFAK 959 YESWS+P++V+L+VP+ ++ + + N+++ +GL+ +GL+ KNAILIVEFAK Sbjct: 890 LYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAK 949 Query: 960 D-KQAEGMSPLDAVLEACRLRLRPILMTSFAFIMGVVPLVLSSGAGAEMRHAMGVAVFSG 1018 D + EG ++A L A R+RLRPILMTS AFI+GV+PL +S+GAG+ ++A+G+ V G Sbjct: 950 DLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGG 1009 Query: 1019 MLGVTFFGLLLTPVFYVLIR 1038 M+ T + PVF+V+IR Sbjct: 1010 MVSATLLAIFFVPVFFVVIR 1029 Score = 92.6 bits (230), Expect = 4e-21 Identities = 87/531 (16%), Positives = 182/531 (34%), Gaps = 50/531 (9%) Query: 544 IRSSGIALLVYAGLMVLTWLGFASTPTGFVPSQDKQYLVAFAQLPDAASLDRTEDVIKRM 603 IR A ++ LM+ L P P+ + A P A +D + ++ Sbjct: 6 IRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYP-GADAQTVQDTVTQV 64 Query: 604 SELALKQ-PGVENAIAFPGLSINGFTNSPNNGVVFVALKPFDERKDPSLSANAIAGALNG 662 E + + ++ ++S + + + F DP ++ + L Sbjct: 65 IEQNMNGIDNLM--------YMSSTSDSAGSVTITLT---FQSGTDPDIAQVQVQNKLQL 113 Query: 663 QFASIQEAYMAIFPPPPVQGLGTIGGFRLQIE---DRGNLGYDELYKETQNIITKSRSVP 719 + + + + + + D D++ + + Sbjct: 114 ATPLLPQE----VQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNV-----KD 164 Query: 720 ELAGL--FTSYTVNVPQVDAAI--DREKAKTHGVAVSDIFDTL-----QVYLGSLYANDF 770 L+ L + Q I D + + + D+ + L Q+ G L Sbjct: 165 TLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQL-GGTP 223 Query: 771 NRFGRTYQVNVQAEQQFRQDADQIGQLKVRNNL-GEMIPLATFVKVSDTAGPDRVM-HYN 828 G+ ++ A+ +F ++ ++ G++ +R N G ++ L +V V+ N Sbjct: 224 ALPGQQLNASIIAQTRF-KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARIN 282 Query: 829 GFITAEINGAAAPGFSSGQAQTAVEKL---LREELPNGM----VYEWTDLTYQQILSGNT 881 G A + A G ++ A++ L+ P GM Y+ T I Sbjct: 283 GKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVK 342 Query: 882 ALFVFPLCVLLAFLVLAAQYESWSLPLAVILIVPMTLLSAIAGVIIAGSDNNIFTQIGLI 941 LF ++L FLV+ ++ L + VP+ LL A + G N T G++ Sbjct: 343 TLF---EAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMV 399 Query: 942 VLVGLACKNAILIVE-FAKDKQAEGMSPLDAVLEACRLRLRPILMTSFAFIMGVVPLVLS 1000 + +GL +AI++VE + + + P +A ++ ++ + +P+ Sbjct: 400 LAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFF 459 Query: 1001 SGAGAEMRHAMGVAVFSGMLGVTFFGLLLTPVF-YVLIRNYVGRQEARKAA 1050 G+ + + + S M L+LTP L++ K Sbjct: 460 GGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGG 510
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.0 bits (70), Expect = 0.011 Identities = 22/185 (11%), Positives = 54/185 (29%), Gaps = 16/185 (8%) Query: 213 ELDVVRADARLAAVEATVPQLQAEQARQRNRIATLLGERPDTLSVDLSPSKLPAIAKALP 272 +L + A+A ++++ Q + EQ R + ++ E + L Sbjct: 126 KLTALGAEADTLKTQSSLLQARLEQTRYQILSRSI--ELNKLPELKLPDEPYFQNVSEEE 183 Query: 273 IGDATQVLRNRPDIRAAERQLAASTARIGVATADLFPRVSLSGFLGYTAGRGSQIGSSAA 332 + T +++ + + Q + A+ L + + Sbjct: 184 VLRLTSLIKEQ--FSTWQNQKYQKELNLDKKRAE------RLTVLARINRYENLSRVEKS 235 Query: 333 RAWSLGP-----SITWAAF-DLGSVRAQIRSADADAEGALANYEQQVLLALEESENAFSD 386 R +I A + + + + + L E ++L A EE + Sbjct: 236 RLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQL 295 Query: 387 YDKRQ 391 + Sbjct: 296 FKNEI 300
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 239 bits (612), Expect = 3e-71 Identities = 116/530 (21%), Positives = 217/530 (40%), Gaps = 46/530 (8%) Query: 250 GMSVGVFGLQRASVGELMPELQKIFGPQSGMPLAGMVRFLPIERTNSVVAISSQPEYLRE 309 + V L + +L P L + +G G V ++V+ ++ + ++ Sbjct: 126 EVVTRVVPLTNVAARDLAP-LLRQLNDNAG---VGSVVHYE---PSNVLLMTGRAAVIKR 178 Query: 310 VGEWIHTIDEGGGNEPQMYVYDVRNMKATDLAKYLRQIYG---TGAIKDDSPAKVAPGLR 366 + + +D G + + A D+ K + ++ A+ A V R Sbjct: 179 LLTIVERVDNAGDRS--VVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADER 236 Query: 367 TTTLSSLNSSGGSGSGGMSSSSGLGGNSSGMSNGMSNGGGFGNSQGMNNSQNSADSESEG 426 T + ++ S ++ L + +QG +++ Sbjct: 237 TNAVL-VSGEPNSRQRIIAMIKQLDRQQA--------------TQGNTKVIYLKYAKASD 281 Query: 427 DDQSGSEADSSSQDDSGSNAGSKSLDASTRITAQKSSNQLLVRTRPAQWKEIESAIKRLD 486 + + S+ Q + + +LD + I A +N L+V P ++E I +LD Sbjct: 282 LVEVLTGISSTMQSEKQAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLD 341 Query: 487 NPPLQVQIETRILEVKLTGELDMGVQWY-----------LGRLAGNSGTTGNVTNTPGSQ 535 QV +E I EV+ L++G+QW G + N N G+ Sbjct: 342 IRRPQVLVEAIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGT- 400 Query: 536 GSLGTGGAALAATDSFFYSFVSNNLQVALRALETNGRTQVLSAPSLVVMNNQQAQIQVGD 595 + +AL++ + F N + L AL ++ + +L+ PS+V ++N +A VG Sbjct: 401 -VSSSLASALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQ 459 Query: 596 NIPISQTSINTNTATNTTLSSVEYVQTGVILDVVPRINPGGLVYMDIQQQVSDADTGTAS 655 +P+ S T+ +VE G+ L V P+IN G V ++I+Q+VS +S Sbjct: 460 EVPVLTGSQTTSGDNIFN--TVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASS 517 Query: 656 TDLNGNPRISTRSVSTQVAAQSGQTVLLGGLIKQDNSETVSAVPYLGRIPGLKWLFGNSS 715 T + +TR+V+ V SG+TV++GGL+ + S+T VP LG IP + LF ++S Sbjct: 518 TSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTS 577 Query: 716 KSKDRTELIVLITPRVITSSSQARQVTDD----YRQQMQLLKPEVSRTSM 761 K + L++ I P VI + RQ + + + + + +M Sbjct: 578 KKVSKRNLMLFIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRGKENNDAM 627 Score = 104 bits (261), Expect = 3e-25 Identities = 63/282 (22%), Positives = 116/282 (41%), Gaps = 10/282 (3%) Query: 77 AAAPAARPAEAGDIVFNFTNQPIQAVINSIMGDLLHENYSIAQGVKGDVSFSTSKPVNKQ 136 AA RPA A + +F IQ IN++ +L ++ I V+G ++ + +N++ Sbjct: 17 FAALLFRPAAAEEFSASFKGTDIQEFINTVSKNL-NKTVIIDPSVRGTITVRSYDMLNEE 75 Query: 137 QALSILETLLSWTDNAMIKQGNRYVILPSNQAVAGKLVPEMPVAQPAAG--MSARLFPLR 194 Q ++L A+I N + + ++ VP A P G + R+ PL Sbjct: 76 QYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLT 135 Query: 195 YISATEMQKLLKPFARENAFLLV--DPARNVLSLAGTPEELANYQDTIDTFDVDWLKGMS 252 ++A ++ LL+ V NVL + G + + VD S Sbjct: 136 NVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIV--ERVDNAGDRS 193 Query: 253 VGVFGLQRASVGELMPELQKIFGPQSG--MPLAGMVRFLPIERTNSVVAISSQPEYLREV 310 V L AS +++ + ++ S +P + + + ERTN+V+ +S +P + + Sbjct: 194 VVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVL-VSGEPNSRQRI 252 Query: 311 GEWIHTIDEGGGNEPQMYVYDVRNMKATDLAKYLRQIYGTGA 352 I +D + V ++ KA+DL + L I T Sbjct: 253 IAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQ 294
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 43.0 bits (101), Expect = 1e-07 Identities = 20/35 (57%), Positives = 26/35 (74%), Gaps = 2/35 (5%) Query: 1 MRRT--QRGFTLLEVLLVISLLGVLLVLVAGALLG 33 MR T QRGFTLLE+++VI ++GVL LV L+G Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMG 35
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 34.2 bits (78), Expect = 6e-05 Identities = 18/42 (42%), Positives = 27/42 (64%), Gaps = 2/42 (4%) Query: 4 SQSGFTLLEMLAALTVMAVCSGVLLVAFGQSA--RSLQQVSR 43 Q GFTLLEM+ L +M V +G++L+AF S + Q ++R Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLAR 43
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 40.3 bits (94), Expect = 4e-07 Identities = 19/50 (38%), Positives = 31/50 (62%) Query: 1 MRTSVASRGFTLMEMLVVLVLMSIAVGLVGFGLQQGLSTASERRAVGDMV 50 MR + RGFTL+E++VV+V++ + LV L A +++AV D+V Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIV 50
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 118 bits (296), Expect = 4e-37 Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 9/140 (6%) Query: 9 KPARRQGGFTLLEMLAVIVLLGIVATIVVRQVGGNVDKGKYGAGKAQLASLGMKVESYAL 68 + +Q GFTLLE++ VIV++G++A++VV + GN +K + + +L ++ Y L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKL 61 Query: 69 DVGSPPKT---LQQLTEKPGNA---SNWNGPYAKPSDLKDPFGHAFGYRFPGQHGSFDLI 122 D P T L+ L E P +N+N DP+G+ + PG+HG++DL+ Sbjct: 62 DNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLL 121 Query: 123 FYGQDGQPGGEGYSADLGNW 142 G DG+ G E D+ NW Sbjct: 122 SAGPDGEMGTED---DITNW 138
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 318 bits (817), Expect = e-108 Identities = 138/405 (34%), Positives = 215/405 (53%), Gaps = 8/405 (1%) Query: 1 MSLFKYRALDAQGAAQNGTLEARDQDAAIAALQKRGLMVLQVDVAGLGGLRRVLGSGL-- 58 M+ + Y+ALDAQG GT EA A L++RGL+ L VD + +GL Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKS-GSTGLSL 59 Query: 59 -----LNGAALVSFTQQLATLLGAGQPLERSLGILLKQPGQPQTRALIERIREQVKAGKP 113 L+ + L T+QLATL+ A PLE +L + KQ +P L+ +R +V G Sbjct: 60 RRKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHS 119 Query: 114 LSVALEEEGSQFSPLYISMVRAGEAGGALESTLRQLSDYLERSQLLRGEVINALIYPAFL 173 L+ A++ F LY +MV AGE G L++ L +L+DY E+ Q +R + A+IYP L Sbjct: 120 LADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVL 179 Query: 174 VVGVLGSLALLLAYVVPQFVPIFKDLGVPIPLITEVILDLGQFLGDYGLAVFASLIALIW 233 V + +++LL+ VVP+ V F + +PL T V++ + + +G + +L+A Sbjct: 180 TVVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFM 239 Query: 234 GMAIRMRDPQRRERRDRRLLGIRVIGPLLQRIEAARLTRTLGTLLTNGVALLQALVIARQ 293 + +R +RR RRLL + +IG + + + AR RTL L + V LLQA+ I+ Sbjct: 240 AFRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGD 299 Query: 294 VCTNRALQAQVGQAAESVKGGGTLASAFGAQPLLPDLALQMIEVGEQAGELDTMLLKVAD 353 V +N + ++ A ++V+ G +L A L P + MI GE++GELD+ML + AD Sbjct: 300 VMSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAAD 359 Query: 354 VFDVEAKRGIDRMLAALVPALTVVMAGMVAVIMLAIMLPLMSLTS 398 D E + L P L V MA +V I+LAI+ P++ L + Sbjct: 360 NQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNT 404
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 52.8 bits (126), Expect = 6e-09 Identities = 34/150 (22%), Positives = 59/150 (39%), Gaps = 34/150 (22%) Query: 426 TTDAAGNSVQGMKVEYFSNTNWSGDAAVTRTEQHVDLDWANDKNLPFESNTSTSDPYTTK 485 + + +S QG+ YFS+ N+ VT + +L S+ + Sbjct: 37 LLNESESSSQGLLGYYFSDLNFQAPMVVTSST---------TGDLSIPSSELEN------ 81 Query: 486 GSTAGELNGDTSSTSIRYTGKITPTQSGEQVFKVRADGAVRLWVNGKKIIDNGDGKPLPG 545 + + S ++G I +S E F AD V +WV+ +++I+ Sbjct: 82 -----IPSENQYFQSAIWSGFIKVKKSDEYTFATSADNHVTMWVDDQEVIN------KAS 130 Query: 546 NSIPPTIPEFAKINLEAGQSYDVKLEYSRR 575 NS KI LE G+ Y +K++Y R Sbjct: 131 NSN--------KIRLEKGRLYQIKIQYQRE 152
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 92.0 bits (228), Expect = 3e-25 Identities = 37/204 (18%), Positives = 77/204 (37%), Gaps = 5/204 (2%) Query: 16 QRRAPKGEKRREELLDAALQVFSLEGYTGASVAKVAAIVGISVAGLLHHFPSKISLLMGV 75 ++ + ++ R+ +LD AL++FS +G + S+ ++A G++ + HF K L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 76 LERRDEVNGRIAAQV---RTDNTLTGLLGGLRAINRSNATAPGVVRAFSILN--AESLVD 130 E + G + + + L+ L L + S T I+ E + + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 131 SQPAYEWFQTRYERIHAHLLGQFSGLVERGEVRADVDLDKVVQQLLAMMDGLQIQWLRFP 190 + + + + +E + AD+ + + + GL WL P Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAP 182 Query: 191 DQVDLIECFDAYIAQVDATVRARP 214 DL + Y+A + P Sbjct: 183 QSFDLKKEARDYVAILLEMYLLCP 206
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.9 bits (210), Expect = 3e-21 Identities = 36/135 (26%), Positives = 61/135 (45%), Gaps = 1/135 (0%) Query: 2 RLLLVEDHVPLADELLAALGRQGYAVDWLADGRDAVYQGASEPYDLIVLDLGLPGMPGLE 61 +L+ +D + L AL R GY V ++ A+ DL+V D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLQQWRGKGLATPVLILTARGSWAERIEGLKAGADDYLTKPFHPEELQLRI-QALLRRSH 120 +L + + PVL+++A+ ++ I+ + GA DYL KPF EL I +AL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 GMANQPTLESAGLNL 135 + G+ L Sbjct: 125 RPSKLEDDSQDGMPL 139
>PHAGEIV#Gene IV protein signature. Length = 426 Score = 30.3 bits (68), Expect = 0.042 Identities = 16/51 (31%), Positives = 22/51 (43%) Query: 740 AETQDEKAEGYGGAAGGLAGALAGGAAGAAIGSIVPVVGTAIGGLVGAFLG 790 E Q A + AAG G +AGG + S++ G + G G LG Sbjct: 205 FEVQQGDALDFSFAAGSQRGTVAGGVNTDRLTSVLSSAGGSFGIFNGDVLG 255
>PF05272#Virulence-associated E family protein Length = 892 Score = 395 bits (1016), Expect = e-127 Identities = 138/422 (32%), Positives = 207/422 (49%), Gaps = 29/422 (6%) Query: 327 WKDQLARSENGALIAHMQNIELILGNDERWAGVISFSAFSSKIVKLRAAPYGGGTGDWAD 386 +L L + L + AG ++F + V +RA P+ G D Sbjct: 436 EVARLRLRGRWLLKPRRAALIEALRSAPALAGCVAFDELREQPVAVRAFPWRKAPGPLED 495 Query: 387 IDDMRVMKWLAQVYN-LRVKASSVIEAVSIVAHDHAFHPVREYLQKLEWDQVPRLEQWLI 445 D +R+ ++ Y A + +A+++ A + HP R++++ +WD+VPRLE+WL+ Sbjct: 496 ADVLRLADYVETTYGTGEASAQTTEQAINVAADMNRVHPFRDWVKAQQWDEVPRLEKWLV 555 Query: 446 DVMGVEPS-------EYVKKVGKRWMISAVARVMRPGCKADSVLILEGAQGAGKSTAMSI 498 V+G P Y++ VGK ++ VARVM PGCK D ++LEG G GKST ++ Sbjct: 556 HVLGKTPDDYKPRRLRYLQLVGKYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINT 615 Query: 499 LGG-DWFMDTPFALGD-KDGFQAIRGKWIVELGELDSFNKAESTKAKQFFSASTDTYRES 556 L G D+F DT F +G KD ++ I G EL E+ +F +A++ K FFS+ D YR + Sbjct: 616 LVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELSEMTAFRRADAEAVKAFFSSRKDRYRGA 675 Query: 557 YGRRTNDVPRQCVFVGTTNQEEYLKDATGNRRYWPVACT-KVELEQLREIRDQLWAEAMF 615 YGR D PRQ V TTN+ +YL D TGNRR+WPV + L L++ R QL+AEA+ Sbjct: 676 YGRYVQDHPRQVVIWCTTNKRQYLFDITGNRRFWPVLVPGRANLVWLQKFRGQLFAEALH 735 Query: 616 CFQAGEIWWV-NRDESSMFAEAQDERFVVDEWEGLILNWL-------EESQIGETTSGNE 667 + AGE ++ DE F Q+ R V +G + L E + S N Sbjct: 736 LYLAGERYFPSPEDEEIYFRPEQELRLVETGVQGRLWALLTREGAPAAEGAAQKGYSVNT 795 Query: 668 LLGT------ALKLDAGHWGKPEQMRVGAIMHRLGWKRARSSVLSKSGLRQWVYKKPANW 721 T AL D G + +V ++ GW+ R + SG R+ Y +P W Sbjct: 796 TFVTIADLVQALGADPGKSSPMLEGQVRDWLNENGWEYLRET----SGQRRRGYMRPQVW 851 Query: 722 GR 723 Sbjct: 852 PP 853
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 372 bits (957), Expect = e-129 Identities = 137/364 (37%), Positives = 199/364 (54%), Gaps = 16/364 (4%) Query: 4 QLLTLPHSPALATSIRATAQVFEDPKSRALLAHVRQVAPSDASVLIIGETGTGKELVARH 63 S S V + + + ++ +D +++I GE+GTGKELVAR Sbjct: 120 AEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 64 VHELSARRDKPFVAVNCGAFSENLIEAELFGHDKGAFTGAISAKAGWFEEANGGTLFLDE 123 +H+ RR+ PFVA+N A +LIE+ELFGH+KGAFTGA + G FE+A GGTLFLDE Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 124 IGDLPMTLQVKLLRVLQEREVVRLGSRKSIPIDVRVLAATNVQLEKAINAGHFREDLYYR 183 IGD+PM Q +LLRVLQ+ E +G R I DVR++AATN L+++IN G FREDLYYR Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 184 LDVVNLELSPLRDRPGDILPLARHFIEVYSQRLRHGPVRISAEAEHKLRTYSWPGNIREL 243 L+VV L L PLRDR DI L RHF++ + R EA ++ + WPGN+REL Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMKAHPWPGNVREL 358 Query: 244 ENVIHHTLLVCRDGIIQRDDL--RMSNLRIERQDEQNQADESAEQL---LNRAFQKLFEE 298 EN++ + +I R+ + + + + E+ A + + + ++ F Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 299 QAGALH---------EKVEDTLLRTAYRFCHHNQVHTASLLGLTRNVTRTRLIKIGELAV 349 AL ++E L+ A NQ+ A LLGL RN R ++ ++G ++V Sbjct: 419 FGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELG-VSV 477 Query: 350 NKRR 353 + Sbjct: 478 YRSS 481
>ICENUCLEATIN#Ice nucleation protein signature. Length = 1258 Score = 38.6 bits (89), Expect = 8e-05 Identities = 27/92 (29%), Positives = 48/92 (52%), Gaps = 2/92 (2%) Query: 514 SHIGNDQSTQVDRNSSSLIKGDETHTTNGVRNTVIGGNELISVSGDTS-VTSGGNLIIQV 572 S I +STQ+ N S LI G + T G R+T+I G + + ++G+ + +G + Sbjct: 1087 SLIAGPESTQITGNRSMLIAGKGSSQTAGYRSTLISGADSVQMAGERGKLIAGADSTQTA 1146 Query: 573 GSQAHVTA-VNVVINAGMSLTLQAGGNHIVIS 603 G ++ + A N + AG L AG + I+++ Sbjct: 1147 GDRSKLLAGNNSYLTAGDRSKLTAGNDCILMA 1178 Score = 37.4 bits (86), Expect = 2e-04 Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 8/88 (9%) Query: 516 IGNDQSTQVDRNSSSLIKGDETHTTNGVRNTVIGGNELISVSGDTS-VTSGGNLIIQVGS 574 I STQ + S L+ G+ ++ T G R+ + GN+ I ++GD S +T+G N I+ G Sbjct: 1137 IAGADSTQTAGDRSKLLAGNNSYLTAGDRSKLTAGNDCILMAGDRSKLTAGINSILTAGC 1196 Query: 575 QAHVTAVNVVINAGMSLTLQAGGNHIVI 602 ++ + N TL AG N ++I Sbjct: 1197 RSKLIGSN-------GSTLTAGENSVLI 1217 Score = 30.9 bits (69), Expect = 0.021 Identities = 27/115 (23%), Positives = 45/115 (39%), Gaps = 10/115 (8%) Query: 521 STQVDRNSSSLIKGDETHTTNGVRNTVIGGNELISVSGDTS-VTSGGNLIIQVGSQAHVT 579 STQ + +S L G + +T G +++I G + S + +G Q+ +T Sbjct: 902 STQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTASFKSTLMAGYGSSQTAREQSSLT 961 Query: 580 AVNVVINAGMSLTLQAGGNHIVISSGGIFSSVPIVQGGSPMAGVSPLQALQAPST 634 AG T AG + +I+ G S+ + AG Q + ST Sbjct: 962 -------AGYGSTSMAGYDSSLIAGYG--STQTAGYQSTLTAGYGSTQTAEHSST 1007 Score = 29.7 bits (66), Expect = 0.044 Identities = 20/78 (25%), Positives = 32/78 (41%), Gaps = 2/78 (2%) Query: 521 STQVDRNSSSLIKGDETHTTNGVRNTVIGGNELISVSGDTSVTSGGNLIIQVGSQAH--V 578 STQ + +S L G + +T G +++I G +G S+ + G Q + Sbjct: 854 STQTAQENSDLTTGYGSTSTAGYDSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLT 913 Query: 579 TAVNVVINAGMSLTLQAG 596 T AG +L AG Sbjct: 914 TGYGSTSTAGYESSLIAG 931
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.2 bits (190), Expect = 1e-18 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 1/117 (0%) Query: 2 HILLIEDDTKTGEYLKKGLGESGYKVDWTQHGADGLHLALENRYDLIVLDVMLPGIDGWQ 61 IL+ +DD L + L +GY V T + A DL+V DV++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 IIEVLRARQ-DVPVLFLTARDQLQDRIRGLELGADDYLVKPFSFTELLLRIRTILRR 117 ++ ++ + D+PVL ++A++ I+ E GA DYL KPF TEL+ I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 54.1 bits (130), Expect = 2e-10 Identities = 26/158 (16%), Positives = 57/158 (36%), Gaps = 7/158 (4%) Query: 78 IDQDRFRLTLRQTQA-TVAERQETWEQARRENKRNRGLGNLVAREQLEESQSREARALSA 136 ++Q+ + ++ ++ + + + + L E L+ + R+ Sbjct: 255 LEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILD--KLRQTTDNIG 312 Query: 137 LGESRVAVDAAQLNLDRSVIRSPVDGYLNDRAPRDH-EFVTAGRPVLSVV-DSASFHIDG 194 L +A + SVIR+PV + VT ++ +V + + + Sbjct: 313 LLTLELA--KNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTA 370 Query: 195 YFEETKLDGIHVGQGVDIRVIGDNARLTGHVVSIVAGI 232 + + I+VGQ I+V G++V V I Sbjct: 371 LVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNI 408 Score = 47.1 bits (112), Expect = 3e-08 Identities = 21/109 (19%), Positives = 44/109 (40%), Gaps = 7/109 (6%) Query: 50 IAPDVSGLIQKVEVTDNQPVHKGQVLFTIDQDRFRLTLRQTQATVAERQETWEQARRENK 109 I P + +++++ V + + V KG VL + +TQ+++ QAR E Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLL-------QARLEQT 151 Query: 110 RNRGLGNLVAREQLEESQSREARALSALGESRVAVDAAQLNLDRSVIRS 158 R + L + +L E + + + E V + + S ++ Sbjct: 152 RYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQN 200
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 32.7 bits (74), Expect = 0.001 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 15/76 (19%) Query: 11 LPENTTYSAAAASNTLARAMPNAIRNALGTLGLVAAR-----TQPSIFPLPSRN------ 59 LP NTT AS L + P A +A T LVA T S+F L +R+ Sbjct: 843 LPTNTTNKVRFASYALIKNAPFARYSA--TPNLVAINQHDFGTIESVFELANRSNDIDTL 900 Query: 60 --VSGGEKEDDLEILL 73 SG + D L+ LL Sbjct: 901 YANSGAQGRDLLQTLL 916
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 65.6 bits (160), Expect = 4e-16 Identities = 20/80 (25%), Positives = 32/80 (40%), Gaps = 6/80 (7%) Query: 4 PDHVPRQAIALSYDGQ--QAPTLSAKGDDQLAEAILAIAREYEVPIYENAELVK-LLARM 60 P H+ AI + Y P ++ K D + + IA E VPI + L + L Sbjct: 264 PTHI---AIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEEEGVPILQRIPLARALYWDA 320 Query: 61 ELGDSIPEPLYRTIAEIIAF 80 + IP AE++ + Sbjct: 321 LVDHYIPAEQIEATAEVLRW 340
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 35.5 bits (82), Expect = 3e-04 Identities = 33/191 (17%), Positives = 64/191 (33%), Gaps = 44/191 (23%) Query: 37 RLRPHVKTSKSLPVIQAQMAAGARGVTVSTLKEAEHCFAEGISDVFYAVAIAPGKLDQAL 96 +R ++ V++A A G + + A FA + L++A+ Sbjct: 20 IVRQAATHARVWSVVKAN-AYGHGIERIWSAIGATDGFA---------LLN----LEEAI 65 Query: 97 KLRRIGCRLSIL--------TDSVVAAQAIVAFGQQHDEQFQ------------VWIEID 136 LR G + IL D + Q + + Q + ++++++ Sbjct: 66 TLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDIYLKVN 125 Query: 137 CDGHRSGLTVEDNALIEVARTL-VEGGMQLRGVMTHAGSSYDLDTPEALQALAEQ----- 190 +R G + ++ V + L + +M+H + D A EQ Sbjct: 126 SGMNRLGFQPDR--VLTVWQQLRAMANVGEMTLMSHFAEAEHPDGISGAMARIEQAAEGL 183 Query: 191 --ERLLCVSAA 199 R L SAA Sbjct: 184 ECRRSLSNSAA 194
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 4e-05 Identities = 11/79 (13%), Positives = 30/79 (37%), Gaps = 7/79 (8%) Query: 48 FVAEHDGQLVG-VAFTCHQGDWSSIGLVIVSDEHQGKGLGRRLMNLCLDATAPRTP---I 103 F+ + +G + + ++ I + V+ +++ KG+G L++ ++ + Sbjct: 68 FLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLM 127 Query: 104 LNATESGAP---LYRSMGF 119 L + Y F Sbjct: 128 LETQDINISACHFYAKHHF 146
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 51.1 bits (122), Expect = 4e-09 Identities = 37/137 (27%), Positives = 52/137 (37%), Gaps = 1/137 (0%) Query: 402 VVAAPDPAFEAQPPAYA-PAPAAVQPEAKAEPAPQIKPEPEPQPEPKPAPVEEIDLPWNE 460 V + AQP + APA ++P +P P+ EPEP+PEP P P +E + + Sbjct: 37 VHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEK 96 Query: 461 SKAPVAEKPAEPEPEPEPEPDPVAEVEAEPQPEPVAEPVLETVSEQPDLTPMPAPAPASP 520 K KP + +P+ D P P T S T P + AS Sbjct: 97 PKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASG 156 Query: 521 VPDAPQAQPSPPVEEQQ 537 + QP P Q Sbjct: 157 PRALSRNQPQYPARAQA 173 Score = 42.7 bits (100), Expect = 3e-06 Identities = 25/124 (20%), Positives = 38/124 (30%) Query: 419 PAPAAVQPEAKAEPAPQIKPEPEPQPEPKPAPVEEIDLPWNESKAPVAEKPAEPEPEPEP 478 P +V A A+ P +P P+P +P P E + V EKP Sbjct: 47 AQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPK 106 Query: 479 EPDPVAEVEAEPQPEPVAEPVLETVSEQPDLTPMPAPAPASPVPDAPQAQPSPPVEEQQV 538 V + + + +P + T A A S + + P Q Sbjct: 107 PVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQ 166 Query: 539 TPAM 542 PA Sbjct: 167 YPAR 170 Score = 38.0 bits (88), Expect = 8e-05 Identities = 20/117 (17%), Positives = 28/117 (23%), Gaps = 5/117 (4%) Query: 388 ADATPVASPASTPPVVAAPDPAFEAQPPAYAPAPAAVQPEAKAEPAPQIKPEPEPQPEPK 447 T VA PP P P +P EA K Sbjct: 50 ISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVK 109 Query: 448 PAPVEEIDLPWNESKAPVAEKPAEPEPEP-----EPEPDPVAEVEAEPQPEPVAEPV 499 + D+ ES+ + P PV V + P+ +P Sbjct: 110 KVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQ 166 Score = 37.6 bits (87), Expect = 1e-04 Identities = 27/109 (24%), Positives = 38/109 (34%) Query: 464 PVAEKPAEPEPEPEPEPDPVAEVEAEPQPEPVAEPVLETVSEQPDLTPMPAPAPASPVPD 523 E P +P PEP +P E E P+P A V+E +P P P P D Sbjct: 58 ADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRD 117 Query: 524 APQAQPSPPVEEQQVTPAMLEAIPDSAYLSAPMDRDDEPPADDDYVEPD 572 + P + PA + +A S P+ P +P Sbjct: 118 VKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQ 166 Score = 31.9 bits (72), Expect = 0.007 Identities = 17/85 (20%), Positives = 25/85 (29%), Gaps = 2/85 (2%) Query: 460 ESKAPVAEKPAEPEPEPEPEPDPVAEVEAEPQPEP--VAEPVLETVSEQPDLTPMPAPAP 517 E AP + EP + EP EP EP+ E E P + P P P Sbjct: 42 ELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKP 101 Query: 518 ASPVPDAPQAQPSPPVEEQQVTPAM 542 + + + + Sbjct: 102 KPKPKPVKKVEQPKRDVKPVESRPA 126
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 60.1 bits (145), Expect = 7e-13 Identities = 61/264 (23%), Positives = 97/264 (36%), Gaps = 27/264 (10%) Query: 4 LAGKRVLIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLKGRVEEFAAGWGSGPELCF 63 + GK I G A I +A + +GA +A N + +V E F Sbjct: 6 IEGKIAFITGAAQ--GIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE-AF 62 Query: 64 PCDVASDEEINKVFEELSKKWDGLDVIVHSVGF---APGDQLDGDFTNATTREGFRIAHD 120 P DV I+++ + ++ +D++V+ G L + AT F + Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEAT----FSVN-- 116 Query: 121 ISAYSFVALAKAGREMMKGRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRYLAGSL 180 S F A + MM R+GS++T+ A + +KA+ + L L Sbjct: 117 -STGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLEL 175 Query: 181 GPEGTRVNAVSAGPIRTL-----------AASGIKNFRKMLAANEAQTPLRRNVTIDEVG 229 R N VS G T A IK L + PL++ ++ Sbjct: 176 AEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGS---LETFKTGIPLKKLAKPSDIA 232 Query: 230 NAGAFLCSDLASGISGEIMYVDGG 253 +A FL S A I+ + VDGG Sbjct: 233 DAVLFLVSGQAGHITMHNLCVDGG 256
>SECA#SecA protein signature. Length = 901 Score = 29.5 bits (66), Expect = 0.046 Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 6/49 (12%) Query: 269 RRAAHILIEVN------DKLNDDQAKAKVEEIQQRLAKGEDFAALAKEF 311 RR ++ +N +KL+D++ K K E + RL KGE L E Sbjct: 19 RRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEA 67
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 116 bits (292), Expect = 7e-38 Identities = 44/88 (50%), Positives = 61/88 (69%) Query: 2 NKSELIDAIAASADIPKAAAGRALDAVIESVTGALKAGDSVVLVGFGTFSVTDRPARIGR 61 NK +LI +A + ++ K + A+DAV +V+ L G+ V L+GFG F V +R AR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKTLEIAAAKKPGFKAGKALKEAV 89 NPQTG+ ++I A+K P FKAGKALK+AV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.034 Identities = 13/81 (16%), Positives = 29/81 (35%), Gaps = 6/81 (7%) Query: 292 DWLVQVPWKAQSKVRLDLARAEAILDADHYGLDEVKERILEYLAVQKRVKKIRGP----- 346 DW+ W ++ L D+ +++ + V ++ P Sbjct: 537 DWVKAQQWDEVPRLEKWLVHVLGKTPDDYKPRRLRYLQLVGKYILMGHVARVMEPGCKFD 596 Query: 347 -VLCLVGPPGVGKTSLAESIA 366 + L G G+GK++L ++ Sbjct: 597 YSVVLEGTGGIGKSTLINTLV 617
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.3 bits (63), Expect = 0.048 Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 23/147 (15%) Query: 22 EKLIERLLIALLADGHMLVEGAPGLAKT---KAIKELAEGIEAQFHRIQFTPDLLPADIT 78 +++ L + D +++ G G K +A+ + + F I +P D+ Sbjct: 147 QEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAA--IPRDLI 204 Query: 79 GTEIYRPETGSFV---------FQQ---GPIFHNLVLADEINRAPAKVQSALLEAMAERQ 126 +E++ E G+F F+Q G +F DEI P Q+ LL + + + Sbjct: 205 ESELFGHEKGAFTGAQTRSTGRFEQAEGGTLF-----LDEIGDMPMDAQTRLLRVLQQGE 259 Query: 127 VS-VGRSTYDLSPLFLVMATQNPIEQE 152 + VG T S + +V AT ++Q Sbjct: 260 YTTVGGRTPIRSDVRIVAATNKDLKQS 286
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 32.4 bits (73), Expect = 0.005 Identities = 19/65 (29%), Positives = 27/65 (41%), Gaps = 3/65 (4%) Query: 480 PNSSASPADE---NPSRTDQPGTSESLPPDTSGQAASGSAMDDEHTTRPPTPGADSPITG 536 P SPA+ NP+ + PGT + PD + D + TRP +P G Sbjct: 327 PLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRPDSPAVPDRPNG 386 Query: 537 ERRQE 541 R+E Sbjct: 387 RHRKE 391
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 52.4 bits (125), Expect = 7e-09 Identities = 71/429 (16%), Positives = 154/429 (35%), Gaps = 29/429 (6%) Query: 623 ESLTRHDDDEQASAQKAVDLLTEQRNQLREQVGGVIARQKELLRQHEQLLERHQALAPDL 682 TR D Q+ D + N L+ + + K L +++L E L Sbjct: 42 AVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKL 101 Query: 683 EAHPLAAQLLD---RDADKRDGWLSQQLSQLNEVIARDEQRQQALLTLQKDAARLQQQLQ 739 + + ++ + R L + L D + + L + A + L+ Sbjct: 102 RKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLE 161 Query: 740 AATDASQTAARHVAEQLKQLDADQQRLEEELTAFTPLVSP-----QVLEGLRSDASATVM 794 A + + + + ++K L+A++ LE + A Sbjct: 162 KALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKA 221 Query: 795 QLEQQITQRLDQLEQQAEEQQEQRERQQKLEKQQIEQQARLQRQSELALEVTRLDAQQQA 854 L + LE + + LE ++ +AR + A Sbjct: 222 ALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSA 281 Query: 855 SQQALTG----LLGEHATAEQWQQALENAIEQARQTESSAAEALQQIHSQLIQLAGELKS 910 + L L E A E Q L + R+ ++ EA +Q+ ++ +L + K Sbjct: 282 KIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKI 341 Query: 911 GQQQQHAIQQELAELDVQISEWRSQHPELDDAALDTLLTYDDAHVDQLRQQLQATEKNLE 970 + + +++++L + ++H +L++ +A LR+ L A+ + + Sbjct: 342 SEASRQSLRRDLDASREAKKQLEAEHQKLEE-----QNKISEASRQSLRRDLDASREAKK 396 Query: 971 QAKVLLQERDQRLQQHQAQHSDLNDDQQLT------------ADLQTAQEQLAQSEQQCA 1018 Q + L+E + +L + + +L + ++LT A+ + +E+LA+ ++ A Sbjct: 397 QVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELA 456 Query: 1019 DLRAELSED 1027 LRA + D Sbjct: 457 KLRAGKASD 465 Score = 43.1 bits (101), Expect = 7e-06 Identities = 65/403 (16%), Positives = 143/403 (35%), Gaps = 20/403 (4%) Query: 444 AWRDRLKSLTLIANRLKHGHSELPALQQRAGVADQQLDEQRSALELLYREADCEVEAVTE 503 ++R + N LK +S+L DE L + ++++E Sbjct: 54 KVQERADKFEIENNTLKLKNSDL---SFNNKALKDHNDELTEELSNAKEKLRKNDKSLSE 110 Query: 504 QVQILGSLLQDNRKQQRAFEELTRLWASQQDVDRQLADLTRQQQSAQQQREQLNSEGLRV 563 + + L ++A E + + L + + E+ + Sbjct: 111 KASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNF 170 Query: 564 RDELAVAEQTLTVTRQLLERQRLARSASVEELRVQLQDDQPCPVCGSVEHPWHQPEALLE 623 + +TL + LE ++ ++E D ++E A Sbjct: 171 STADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSA--KIKTLEAEKAALAARKA 228 Query: 624 SLTRHDDDEQASAQKAVDLLTEQRNQLREQVGGVIARQKELLRQHEQLLERHQALAPDLE 683 L + + + + + + + A ++ L A LE Sbjct: 229 DLEKALEGAMNFSTADSAKI-KTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLE 287 Query: 684 AHPLAAQLLDRDADKRDGWLSQQLSQLNEVIARDEQRQQALLTLQKDAARLQQQLQAATD 743 A A + D + + L+ L + ++A L+ + +L++Q + + Sbjct: 288 AEKAALEAEKADLEHQSQVLNANRQSLRR---DLDASREAKKQLEAEHQKLEEQNKISEA 344 Query: 744 ASQTAARHVA---EQLKQLDADQQRLEEELTAFTPLVSPQVLEGLRSDASATV---MQLE 797 + Q+ R + E KQL+A+ Q+LEE+ +S + LR D A+ Q+E Sbjct: 345 SRQSLRRDLDASREAKKQLEAEHQKLEEQNK-----ISEASRQSLRRDLDASREAKKQVE 399 Query: 798 QQITQRLDQLEQQAEEQQEQRERQQKLEKQQIEQQARLQRQSE 840 + + + +L + +E E ++ EK++ E QA+L+ +++ Sbjct: 400 KALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAK 442 Score = 38.5 bits (89), Expect = 2e-04 Identities = 45/306 (14%), Positives = 112/306 (36%), Gaps = 6/306 (1%) Query: 622 LESLTRHDDDEQASAQKAVDLLTEQRNQLREQVGGVIARQKELLRQHEQLLERHQALAPD 681 + + D + + + L ++ L + + G + + + L AL + Sbjct: 132 AMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAAL--E 189 Query: 682 LEAHPLAAQLLDRDADKRDGWLSQQLSQLNEVIARDEQRQQALLTLQKDAARLQQQLQAA 741 L L S ++ L A R+ L + A A Sbjct: 190 ARQAELEKALEGAMNFSTA--DSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAK 247 Query: 742 TDASQTAARHVAEQLKQLDADQQRLEEELTAFTPLVSPQVLEGLRSDASATVMQLEQQIT 801 + + + +L+ + TA + + E +A ++ + Q+ Sbjct: 248 IKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVL 307 Query: 802 QRLDQLEQQAEEQQEQRERQQKLEKQQIEQQARLQRQS--ELALEVTRLDAQQQASQQAL 859 Q ++ + + ++Q + E Q++E+Q ++ S L ++ ++ + Sbjct: 308 NANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEH 367 Query: 860 TGLLGEHATAEQWQQALENAIEQARQTESSAAEALQQIHSQLIQLAGELKSGQQQQHAIQ 919 L ++ +E +Q+L ++ +R+ + +AL++ +S+L L K ++ + + Sbjct: 368 QKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTE 427 Query: 920 QELAEL 925 +E AEL Sbjct: 428 KEKAEL 433
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 30.7 bits (69), Expect = 0.003 Identities = 14/57 (24%), Positives = 24/57 (42%) Query: 135 IERYLRAETPYDCAGSFKAEGLGVSLFRSTQGADATSLIGLPLIRLVDMLIKEGVSV 191 + Y+ E YD G +G + QG T+ +G P+ +D+ + G V Sbjct: 66 VNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGGMV 122
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 66.6 bits (162), Expect = 5e-13 Identities = 41/253 (16%), Positives = 74/253 (29%), Gaps = 14/253 (5%) Query: 870 ANSTTQSAPAAEPVQQAAVAHAP--VVETPAVEAPVAETSAVETPAPQAPAAEQTAEVPA 927 + Q+ + P +A V PA P T V + Q + E A Sbjct: 999 TPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDA 1058 Query: 928 VEAPVADDAPVAQPAPEVEVQPAAVEAPAIAAQTELFEAPHAERVVPFTPTPAPAPQAPV 987 E + + V+ E AQ+ T T +A V Sbjct: 1059 TETTAQNREVAKEAKSNVKANTQTNEV----AQSGSETKETQTTETKETATVEKEEKAKV 1114 Query: 988 EAAAHEQVPATESSELPTPVEAPAAEPAAFVKDEPAPYIAPQAAVEEQASAPAEQEPVIV 1047 E ++VP S P ++ +P A E P + + + + ++P Sbjct: 1115 ETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKE 1174 Query: 1048 ETPAV--PVSSTGRAPNDPREVRRRKREEEARRQQETTAASAQ------AESAQPSQATE 1099 + V PV+ + V + A Q + S+ S + Sbjct: 1175 TSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNV 1234 Query: 1100 EKTDVATTEQPAV 1112 E ++ ++ V Sbjct: 1235 EPATTSSNDRSTV 1247 Score = 63.9 bits (155), Expect = 3e-12 Identities = 61/341 (17%), Positives = 101/341 (29%), Gaps = 37/341 (10%) Query: 548 PARANAPVPVEVAAPAPTPAPVAHEPSLFKGLVKSLVSLFATKEEPVVAPAVVEKPA--- 604 P V+ A PS V S A +E V P P+ Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPS-----VPSNNEEIARVDEAPVPPPAPATPSETT 1037 Query: 605 ---AEQRPARNEERRNGRQQS---RGRNNRRDEERKPREERAPREERAERAPREERAPRE 658 AE ++ Q + +N +E K + + ++ E + + Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKE-TQ 1096 Query: 659 ERAPREERAVREPREAREESAPREERPARTSRERKPREAREDRPVRELREPLDAVATAAQ 718 +E V + +A+ E+ +E P TS+ +E E V+ EP A + Sbjct: 1097 TTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSET--VQPQAEP------ARE 1148 Query: 719 AGPAVNLAREERPERAPREERQP--RAPREERQPRAEQAAVAVSEEEEVLLNDEQANDDN 776 P VN+ + + QP QP E V + Sbjct: 1149 NDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQ 1208 Query: 777 QDGNDGSEGDRPRRRSRGQRRRSNRRERQRDANGNVIEGSEENGSEENGAEETVNDEDNS 836 N S ++P+ R R R + A S + S + T + + Sbjct: 1209 PTVNSESS-NKPKNRHR--RSVRSVPHNVEPAT-----TSSNDRSTVALCDLTSTNTNAV 1260 Query: 837 ATDLSAGLGF----TAAAASGVISATAEADAHQQAERANST 873 +D A F A S IS + Q ++T Sbjct: 1261 LSDARAKAQFVALNVGKAVSQHISQLEMNNEGQYNVWVSNT 1301 Score = 50.4 bits (120), Expect = 4e-08 Identities = 57/363 (15%), Positives = 92/363 (25%), Gaps = 80/363 (22%) Query: 750 PRAEQAAVAVSEEEEVLLNDEQANDDNQDGNDGSEGDRPRRRSRG-QRRRSNRRERQRDA 808 P E+ V N+ QA D P S + R + A Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQA-------------DVPSVPSNNEEIARVDEAPVPPPA 1029 Query: 809 NGNVIEGSEENGSEENGAEETVNDEDNSATDLSAGLGFTAAAASGVISATAEADAHQQAE 868 E +E +TV + AT+ A + A+ Sbjct: 1030 PATPSETTETVAENSKQESKTVEKNEQDATE-------------------TTAQNREVAK 1070 Query: 869 RANSTTQSAPAAEPVQQAAVAHAPVVETPAVEAPVAETSAVETPAPQAPAAEQTAEVPAV 928 A S ++ Q VA + ET+ VE E+T EVP V Sbjct: 1071 EAKSNVKANT-----QTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKV 1125 Query: 929 EAPVADDAPVAQPAPEVEVQPAAVEAPAIAAQTELFEAPHAERVVPFTPTPAPAPQAPVE 988 + Q E VQP A A P Sbjct: 1126 TS----QVSPKQEQSE-TVQPQAEPAR---------------------------ENDPTV 1153 Query: 989 AAAHEQVPATESSELPTPVEAPAAEPAAFVKDEPAPYIAPQAAVEEQASAPAEQEPVIVE 1048 Q +++ P + ++ V + + + PA +P + Sbjct: 1154 NIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNS 1213 Query: 1049 TPAVPVSSTGRAPNDPREVRRRKREEEARRQQETTAASAQAESAQPSQATEEKTDVATTE 1108 + N P+ RR + T +S + T T+ ++ Sbjct: 1214 ESS----------NKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSD 1263 Query: 1109 QPA 1111 A Sbjct: 1264 ARA 1266 Score = 45.8 bits (108), Expect = 1e-06 Identities = 30/149 (20%), Positives = 44/149 (29%), Gaps = 22/149 (14%) Query: 979 PAPAPQAPVEAAAHEQVPA--TESSELPTPVEAPAAEPAAFVKDEPAPYIAPQAAVEEQA 1036 VP+ + + E+ EAP PA E +A + E + Sbjct: 991 TVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKT 1050 Query: 1037 SAPAEQEPVIVETPAVPVSSTGRAPNDPREVRRRKREEEARRQQETTAASAQAESAQPSQ 1096 EQ D E + RE + A + E AQ Sbjct: 1051 VEKNEQ--------------------DATETTAQNREVAKEAKSNVKANTQTNEVAQSGS 1090 Query: 1097 ATEEKTDVATTEQPAVQPHHEAEKETEPK 1125 T+E T E V+ +A+ ETE Sbjct: 1091 ETKETQTTETKETATVEKEEKAKVETEKT 1119 Score = 45.8 bits (108), Expect = 1e-06 Identities = 44/240 (18%), Positives = 71/240 (29%), Gaps = 44/240 (18%) Query: 909 VETPAPQAPAAEQTAEVPAV-----EAPVADDAPVAQPAPEVEVQPAAVEAPAIAAQTEL 963 V+T P Q A+VP+V E D+APV PAP + A +++ Sbjct: 992 VDTTNITTPNNIQ-ADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKT 1050 Query: 964 FEAPHAERVVPFTPTPAPAPQAPVEAAAHEQVPATESSELPTPVEAPAAEPAAFVKDEPA 1023 E + T A V A V A + + E E A Sbjct: 1051 VEKNEQD------ATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETA 1104 Query: 1024 PYIAPQAAVEEQASAPAEQEPVIVETPAVPVSSTGRAPNDPREVRRR--KREEEARRQQE 1081 ++E VET + P++ + + + E R+ + Sbjct: 1105 --------------TVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREND 1150 Query: 1082 TTAASAQAESAQPSQATEEK----------------TDVATTEQPAVQPHHEAEKETEPK 1125 T + +S + A E+ T V T P + T+P Sbjct: 1151 PTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPT 1210
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 25.9 bits (56), Expect = 0.006 Identities = 12/21 (57%), Positives = 16/21 (76%), Gaps = 2/21 (9%) Query: 2 SDLLRSAADSW--GEINTQKY 20 SD LR+ ADSW G+IN++ Y Sbjct: 223 SDTLRTLADSWKQGKINSEAY 243
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 27.1 bits (59), Expect = 0.044 Identities = 22/95 (23%), Positives = 36/95 (37%), Gaps = 5/95 (5%) Query: 47 TQSQAVASTTTEYRTEEQRRQKAANQVANDARQEQAVAIADAVVADASGDRLRSEAGKLA 106 T ++A + EQ +A + ARQ+ A+ A+ A+G A Sbjct: 208 TAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAANTYAMPANGS-----VVATA 262 Query: 107 ASASCVPSDPGIADRGKNAARAAMVLSDLLSRADS 141 A + G A + + A VL +L+ A S Sbjct: 263 AGRGLIQVAQGAASLAQAISDAIAVLGRVLASAPS 297 Score = 27.1 bits (59), Expect = 0.048 Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 10/102 (9%) Query: 31 NKVEADWQQKWDRELKTQSQAVASTTTEYRTEEQRRQKAANQVANDARQEQAVAIADAVV 90 +A + + + Q+ A + + EEQ RQ+AA + AN A+ +VV Sbjct: 208 TAAKASIEAAAANKAREQAAA----EAKRKAEEQARQQAAIRAAN----TYAMPANGSVV 259 Query: 91 ADASGDRLRSEAGKLAASASCVPSDPGIADRGKNAARAAMVL 132 A A+G L + + AAS + SD IA G+ A A V+ Sbjct: 260 ATAAGRGL-IQVAQGAASLAQAISD-AIAVLGRVLASAPSVM 299
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 113 bits (285), Expect = 5e-33 Identities = 34/112 (30%), Positives = 51/112 (45%), Gaps = 12/112 (10%) Query: 66 YFEYDSSDLKPEAMRSLDVHA---KDLKANGARVVLEGNTDERGTREYNMALGERRAKAV 122 F ++ + LKPE +LD +L VV+ G TD G+ YN L ERRA++V Sbjct: 222 LFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSV 281 Query: 123 QRYLVLQGVSPAQLELVSYGEERPVATGNDEQS---------WAQNRRVELR 165 YL+ +G+ ++ GE PV + A +RRVE+ Sbjct: 282 VDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIE 333
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 61.2 bits (148), Expect = 3e-12 Identities = 45/260 (17%), Positives = 96/260 (36%), Gaps = 11/260 (4%) Query: 78 ARQTEVEQLEQKKIEQLKQEAVKAAEQKKEESAQKAEEQKAADEAKK----AEQKAEEAK 133 A T E E E KQE+ + +++ + A+ ++ A EAK Q E A+ Sbjct: 1029 APATPSETTETVA-ENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQ 1087 Query: 134 KADDAKKADEAKKVADAKKVEEKQLADIAKKKAEDEAKKKAEEDAKKAAAEEAKKQAADE 193 + K+ + + VE+++ A + +K ++ K ++ K+ +E + QA Sbjct: 1088 SGSETKETQTTET-KETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPA 1146 Query: 194 AKKKAAEDAKKKAAEDAKKKAAADSAKKAQEAARKSAEDKKAQALADLLSDKPERQQALA 253 + + K+ ++ AK+ + + + + + PE Sbjct: 1147 RENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPAT 1206 Query: 254 DERGDETAGSFDDLIR----VRASEGWSRPPS-ARNNMSVTLQIGMLPDGTIASVSIAKS 308 + + S R VR+ P + + N+ S + T A +S A++ Sbjct: 1207 TQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARA 1266 Query: 309 SGDGPFDSSAVAAVKNIGRL 328 + A ++I +L Sbjct: 1267 KAQFVALNVGKAVSQHISQL 1286 Score = 57.0 bits (137), Expect = 5e-11 Identities = 34/205 (16%), Positives = 68/205 (33%), Gaps = 14/205 (6%) Query: 61 ATTQTNQKIAGEAKKTAARQTEVEQLEQKKIEQLKQEAVKAAEQKKEESAQKAEEQKAAD 120 Q + + AR E + A K+E + EQ A + Sbjct: 1001 NNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATE 1060 Query: 121 EAKKAEQKAEEAKKADDA-----KKADEAKKVADAKKVEEKQLADIAKKKAEDEAKKKAE 175 + + A+EAK A + A + + + E K+ A + E E K K E Sbjct: 1061 TTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATV-----EKEEKAKVE 1115 Query: 176 EDAKKAAAEEAKKQAADEAKKKAAEDAKKKAAEDAKKKAAADSAKKAQEAARKSAEDKKA 235 + +E K + + K+ + + AE A++ + K+ Q +A+ ++ Sbjct: 1116 TEKT----QEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQP 1171 Query: 236 QALADLLSDKPERQQALADERGDET 260 ++P + + Sbjct: 1172 AKETSSNVEQPVTESTTVNTGNSVV 1196
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 279 bits (714), Expect = 1e-94 Identities = 66/201 (32%), Positives = 109/201 (54%), Gaps = 4/201 (1%) Query: 238 PTVEVPASQPSDTVTLFMSGDGGWRDLDKVVAGDMAKMGYPVVGIDVLRYYWEHKTPEQT 297 V +S + +F+SGDGGW LDK V G + + G+PVVG L+YYW+ K P+ Sbjct: 40 TQVNAASSHTKPPLVIFLSGDGGWATLDKAVGGILQQQGWPVVGWSSLKYYWKQKDPKDV 99 Query: 298 AADLTDLMNHYRQKWGTKRFILAGYSFGADVMPAIYNRLAADDQNRVDAIILLAFARTGS 357 D +++ Y+ ++GT++ IL GYSFGA+V+P + N + A + V +LL+ +++ Sbjct: 100 TQDTLAIIDKYQAEFGTQKVILIGYSFGAEVIPFVLNEMPARYRKNVLGAVLLSPSQSSD 159 Query: 358 FEIHVDGWLGNAGKEAT--TGQEMARLPAAKVFCVYGIEEKKD-SGCTDTTAVG-EAVQL 413 FEIHV + + + A T E+ + + C+YG E+ C + ++L Sbjct: 160 FEIHVSEMVTSDNQSARYLTLPEVNKQTTVPMLCLYGKEDDAPLHLCPEVKQPNVTVMEL 219 Query: 414 PGGHHFDEDYPALAKRLIDAI 434 GGH FD+DY + K + + Sbjct: 220 SGGHSFDDDYDKVVKLIKGWL 240
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 27.0 bits (59), Expect = 0.046 Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 1/81 (1%) Query: 17 AMNAQVTTAESCTGGGIAEAITRIAGSSAWFEAGYVTYSNAQKTRQLGVSEALFAQVGAV 76 A+ +VT + + GG+AE + S A + ++ Q + L S +F + V Sbjct: 506 ALGMEVTNTAAQSAGGVAEGVFIKNASEALADFMLARFAMDQIQQWLKQSVEIFGENQKV 565 Query: 77 SQPVVEAMVSG-AQRESGARF 96 + + +AM S Q +RF Sbjct: 566 TAELQKAMSSAVQQNADASRF 586
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 27.5 bits (60), Expect = 0.025 Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 7/77 (9%) Query: 24 DSQWQAKWSEQVSAQSQAVATTTAE--YRTEEQRRQKAANQVANDARQEQTAALTDAAVA 81 ++ AK S + +A ++A AE + EEQ RQ+AA + AN A + +V Sbjct: 205 NTLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAAN-----TYAMPANGSVV 259 Query: 82 DAAGGRLRIEAGKLAAT 98 A GR I+ + AA+ Sbjct: 260 ATAAGRGLIQVAQGAAS 276
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 28.0 bits (62), Expect = 0.024 Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 15/88 (17%) Query: 3 ITAQQLLQILPSAGQKAGVFAPVLNTAMSKHQILTPLRIAAFIAQVGHESGQLRYVREIW 62 I AQ+ Q L ++ AG+ A + A+S PL + IA + ++ + + Sbjct: 291 IIAQRAAQGLSTSAAAAGLIASAVTLAIS------PLSFLS-IADKFKRANKIEEYSQRF 343 Query: 63 GPTPQQLGYEGRKDLG----NTVAGDGS 86 ++LGY+G L T A D S Sbjct: 344 ----KKLGYDGDSLLAAFHKETGAIDAS 367
>CHANNELTSX#Nucleoside-specific channel-forming protein Tsx signature. Length = 294 Score = 29.2 bits (65), Expect = 0.014 Identities = 11/27 (40%), Positives = 17/27 (62%), Gaps = 4/27 (14%) Query: 155 GQWSDDDGISWCDGNESSLASARASGW 181 GQW+DD +++ DG S R++GW Sbjct: 262 GQWADDAKLNFGDGP----FSVRSTGW 284
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.0 bits (65), Expect = 0.034 Identities = 10/54 (18%), Positives = 19/54 (35%) Query: 4 SRSRWYGQLYVQVLIGIVIGAAIGYFVPDVGAKLQPFADGFIKLIKMLLAPIIF 57 R+R +G + G+V G +G + FA + + L + Sbjct: 128 ERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLL 181
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.4 bits (146), Expect = 1e-13 Identities = 36/198 (18%), Positives = 74/198 (37%), Gaps = 21/198 (10%) Query: 1 MRSDARKNRERILEVAVVELTADP--AVALSTIAKKAGVGQGTFYRHFPTREKLVFEVYQ 58 + +A++ R+ IL+VA+ + + +L IAK AGV +G Y HF + L E+++ Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 59 FEMQQVASLAEQLLATKPP------KDALREWMDCLVEYAMTKAGLAIAIRQAASVYEFP 112 + L + A P ++ L ++ V + + I + V E Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 113 -----GQTGYVPVQAAAELLLRANERAGTIRSGITADDFFLAIAGI-------WQVDSQS 160 + + E L+ A + + + + + G W QS Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQS 184 Query: 161 QWRLRIAR-LMNLVMDGL 177 + AR + ++++ Sbjct: 185 FDLKKEARDYVAILLEMY 202
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 72.4 bits (177), Expect = 3e-17 Identities = 50/213 (23%), Positives = 89/213 (41%), Gaps = 9/213 (4%) Query: 5 GNTILVTGGTSGIGLGLALRLHKAGNKVIIAGRRKALLDKIVSEHPGI----ESVVLDVT 60 G +TG GIG +A L G + L+K+VS E+ DV Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 61 DPHSIQHSSEALAISHPNLNVLINNAGIMHWEDLTDAKYLSTAENIVTTNLLGTIRMVYA 120 D +I + + +++L+N AG++ L + E + N G + Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLR-PGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 121 FTPNLLKQPSATIVNVSSALAFVPLPATPTYSATKAAVHSFTQSLRVQLADSPVEVIELA 180 + ++ + S +IV V S A VP + Y+++KAA FT+ L ++LA+ + ++ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 181 PPGVRTTL---LGQENDEHAMPLEAFLDEIFKL 210 P T + L + + ++ L E FK Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSL-ETFKT 218
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 93.6 bits (232), Expect = 1e-24 Identities = 51/186 (27%), Positives = 85/186 (45%), Gaps = 8/186 (4%) Query: 31 KTVLITGASSGFGLLLATHLHQQGFNVVGTSRYPEKYAGSVRFKL--------LRLDIDD 82 K ITGA+ G G +A L QG ++ PEK V D+ D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 83 DSSVQAFTDELFKHITRLDVLVNNAGYMVTGLAEETPIETGRQQFETNFWGTVKVTNALL 142 +++ T + + + +D+LVN AG + GL E F N G + ++ Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 143 PYMRRQKNGQIITVSSMVGLIGPPNLSYYAASKHAVEGYFKSLRFELNQFNINVSVIEPG 202 YM +++G I+TV S + +++ YA+SK A + K L EL ++NI +++ PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 203 WFNTNL 208 T++ Sbjct: 189 STETDM 194
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 96.7 bits (240), Expect = 4e-26 Identities = 72/245 (29%), Positives = 108/245 (44%), Gaps = 18/245 (7%) Query: 4 LKQKRAVITGAGSGIGAAIARAYAVEGAYLVLGDRDPVNLANIAEHCRQLGAQVHECVAD 63 ++ K A ITGA GIG A+AR A +GA++ D +P L + + AD Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 64 VGSVEGAQASVDACVEHFGGIDILVNNAGMLTQARCVDLSIEMWNDMLRVDLTSVFVASQ 123 V G IDILVN AG+L LS E W V+ T VF AS+ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 124 RALPHMIAQRWGRIINVASQLGIKGGAELTHYAAAKAGVIGFSKSLALEVAKDNVLVNAI 183 +M+ +R G I+ V S + YA++KA + F+K L LE+A+ N+ N + Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 184 APGPIETPL--------------VAGISSAWKTAKAAELPLGRFGLAEEVAPVAVLLASE 229 +PG ET + + G +KT +PL + ++A + L S Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTG----IPLKKLAKPSDIADAVLFLVSG 241 Query: 230 PGGNL 234 G++ Sbjct: 242 QAGHI 246
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.030 Identities = 10/30 (33%), Positives = 14/30 (46%) Query: 33 TLVGASGCGKSTFLRLLLGQETPSRGLITL 62 L G G GKST + L+G + S + Sbjct: 600 VLEGTGGIGKSTLINTLVGLDFFSDTHFDI 629
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 33.3 bits (76), Expect = 0.007 Identities = 21/108 (19%), Positives = 38/108 (35%), Gaps = 10/108 (9%) Query: 1124 ERERWIANGQADFQSDEGVAPYIE------ELPLQAGQQGVESHIAGNLWQVQVQPGERV 1177 E+E + + + IE + Q Q ++ I L Q G Sbjct: 256 EQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLT 315 Query: 1178 EAGDVLVILESMKMEIPLLAPVAGVVQEVRVQ-PGSAVRAGQRVVVLA 1224 L E + + APV+ VQ+++V G V + ++V+ Sbjct: 316 LE---LAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIV 360
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.9 bits (137), Expect = 2e-12 Identities = 28/170 (16%), Positives = 54/170 (31%), Gaps = 6/170 (3%) Query: 5 TKAALLSYAETQMRSKGYSAFSYADLAAKVGIRKASIHHHFPTKECLGAELINDYINRFN 64 T+ +L A +G S+ S ++A G+ + +I+ HF K L +E+ + Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 65 ETLASI-----ETMHPEPLKRLQAFSQLFVMSANEGLLPLCGALAAEMAALPLSLQGLTR 119 E + L + V LL E +Q R Sbjct: 72 ELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQR 131 Query: 120 DFFNAQLDWLQSTLSQAVRQHNWSLETPLENFAFMLLSSLEGASLIDWTL 169 + D ++ TL + + A ++ + G + +W Sbjct: 132 NLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL-MENWLF 180
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 102 bits (254), Expect = 4e-28 Identities = 62/252 (24%), Positives = 104/252 (41%), Gaps = 8/252 (3%) Query: 6 KGKKLLVVGGTSGMGLETARQFLKAGGSVVLTGSKQDKADAVRAELSPLG-NVSVIVANL 64 +GK + G G+G AR G + +K + V + L + A++ Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 65 MTEEGMNHVRNEINANHSDIGFMVNSAGIFIPKPFIEHDEADYDMYLDLNRATFFITQAV 124 ++ + I I +VN AG+ P + +++ +N F Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 125 VKNMLAAKREGSIVNVGSIGAQAALAGSPATAYSMAKAGLHAVTRNLAIELAHSGIRVNA 184 V + +R GSIV VGS A AY+ +KA T+ L +ELA IR N Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTS--MAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 185 VSPGIVHTSIY-----EGFMDKEAIPDAMKSLNDFHPLGRVGVPEDVANTILFLLSDKTS 239 VSPG T + + ++ I ++++ PL ++ P D+A+ +LFL+S + Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244 Query: 240 WVTGAIWDVDAG 251 +T VD G Sbjct: 245 HITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.0 bits (163), Expect = 5e-16 Identities = 27/199 (13%), Positives = 62/199 (31%), Gaps = 13/199 (6%) Query: 1 MSTRSDLLTSAEILLRTKGYAAFSYADLADDIGIKKASIHHHFPTKEGMAIAIVESYLFR 60 TR +L A L +G ++ S ++A G+ + +I+ HF K + I E Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 61 FRKQLEAINDENVG-----IVDRLKA-FALMFAHSSENGMLPLCGALAAELLALPESLKA 114 + + G + + L ++ E + ++ Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLME-IIFHKCEFVGEMAVVQQ 128 Query: 115 MTKDFFEIHLTWLQENIKKGQDQGVLKPDLDVITVSRFILNALEGASFVSWAMSDDY--- 171 ++ +++ +K + +L DL + + + G +W + Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL-MENWLFAPQSFDL 187 Query: 172 --EKSSGFDLILAGILRSE 188 E ++L L Sbjct: 188 KKEARDYVAILLEMYLLCP 206
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 45.8 bits (108), Expect = 3e-08 Identities = 21/158 (13%), Positives = 55/158 (34%), Gaps = 11/158 (6%) Query: 11 RSVEQKEERRRHLLATARAMLDDSPGALDLGINELARQAQMTKSNVYRYFESSEAVLIDV 70 ++ ++ +E R+H+L A + G + E+A+ A +T+ +Y +F+ + ++ Sbjct: 4 KTKQEAQETRQHILDVALRLFSQQ-GVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 71 LVEEYAGWQAELGVALSQDGKAEATVEDIAAVFAQTLCARPLLCRLTSIMPSILERKLSF 130 + + L K + + + ++ I+ K F Sbjct: 63 WELSESNIGE---LELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 131 ERMVEFKRNLLALRHQAAQAFHARLPEISVDSFEEVIK 168 +A+ QA + + + + I+ Sbjct: 120 VG-------EMAVVQQAQRNLCLESYDRIEQTLKHCIE 150
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 42.3 bits (99), Expect = 8e-07 Identities = 44/187 (23%), Positives = 73/187 (39%), Gaps = 1/187 (0%) Query: 9 VLITGASSGFGEEFARQYAAKGHPLILVARRLDRLQALATTLRHEHGVEIITEQVDLSEV 68 ITGA+ G GE AR A++G + V ++L+ + ++L+ E D+ + Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE-ARHAEAFPADVRDS 69 Query: 69 TAIAALHFSLHERGIEVEILINNAGHGLQGSFLGTSVQSTLDMVQLDIASLTVMTRLFGA 128 AI + + ++IL+N AG G S + ++ + +R Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 129 DMRQRGHGRILLVASLLALWGVEDMAVYGASKAYVLRLGDALHREFKRDGVTVTSLCPGM 188 M R G I+ V S A MA Y +SKA + L E + + PG Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 189 SNTGFAQ 195 + T Sbjct: 190 TETDMQW 196
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 56.0 bits (135), Expect = 9e-11 Identities = 59/338 (17%), Positives = 125/338 (36%), Gaps = 15/338 (4%) Query: 50 LVTAFALGMGISAPIIGVLAHRASKRSLLISACVALLLGNGISAAFNDYYIILAGRVLGG 109 L+ +AL AP++G L+ R +R +L+ + + I A +++ GR++ G Sbjct: 48 LLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAG 107 Query: 110 IGVAVFWTNAALAAKSLSQGRNESLAIGRVLVGISIASVVGVPVGKLIADATNWRMAMWM 169 I A A A ++ G + G + V G +G L+ + + Sbjct: 108 ITGATGAVAGAYIA-DITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSP-HAPFFA 165 Query: 170 MTALSSVALLTVWIWVRPTEESRQK--ENLSDTVRVALRSDVAMTLISSCLMFAGVASVF 227 AL+ + LT + + + ++ + + R MT++++ + + + Sbjct: 166 AAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLV 225 Query: 228 N-----FLATFMEKETGFGEISVTLLLCLYGIADIASNLILSKRVKNDLEPLFRRVLMTM 282 F E + ++ + L +GI + +++ V L R +++ M Sbjct: 226 GQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGER-RALMLGM 284 Query: 283 AAGMC--FLSLFGSLTWAVPIAVIIVASSHAGVSLLIGIDVLQRAGDAGQLINAINVSMI 340 A L F + W ++++AS G+ L + Q + + ++ Sbjct: 285 IADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALT 344 Query: 341 NLGIGIGAAITGLLTDRVGVGAVGWV---GACFILLAL 375 +L +G + + GW GA LL L Sbjct: 345 SLTSIVGPLLFTAIYAASITTWNGWAWIAGAALYLLCL 382
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 27.7 bits (61), Expect = 0.020 Identities = 9/45 (20%), Positives = 24/45 (53%) Query: 56 VTIAAVAREAGVSTALIHNHYPAVAEVIREIQGRSSRAMRDIKHQ 100 ++ +A+ AGV+ I+ H+ +++ EI S + +++ + Sbjct: 32 TSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELE 76
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 28.2 bits (62), Expect = 0.010 Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 6/61 (9%) Query: 3 KGLKRLAEHPDNVVKETLYRGI--NKVVDDKFIHKNFKLGEVYRDKTFVSATPDLSTVNA 60 +GL L E VV YRG+ +K + + +G + DK F+S +PD + +N Sbjct: 456 EGLSSLPETDHRVV----YRGLKLDKPALSDVLKEYTTIGNIIIDKAFMSTSPDKAWIND 511 Query: 61 T 61 T Sbjct: 512 T 512
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 29.1 bits (65), Expect = 0.032 Identities = 18/66 (27%), Positives = 28/66 (42%), Gaps = 5/66 (7%) Query: 136 AGAFGTTLSKDGSLLYV--NNEAAS---TLSVIDLDHQRPVAVVPGFSQPRQGIRVSPDG 190 A + DG++LY+ N+E AS L + + G +PR G R Sbjct: 87 ASLYNLVWYYDGNVLYIFKNSEVASRLIRLQESEAAELKQALQRSGIWEPRFGWRPDASN 146 Query: 191 KTVYVT 196 + VYV+ Sbjct: 147 RLVYVS 152
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 30.3 bits (68), Expect = 0.011 Identities = 23/150 (15%), Positives = 48/150 (32%), Gaps = 13/150 (8%) Query: 139 GTRFEYSNTGYFLLGTVIERVSGVRYADYARARIFTPLSMRDTFIL----DGMSQDKRVA 194 +++ + TV +G D ++ D+F L D + + Sbjct: 367 NNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIVNMDVLI 426 Query: 195 TGYAKGSGGVYTASRNPWNSLGASLVHSSAADLMKWGEN-------FLTAKVGGHAAIQK 247 T AK + + + N G +L+ + G L + +G A K Sbjct: 427 TDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLK 486 Query: 248 MLTPLARINERGEAIAEHSAYCFGLSMDED 277 + N ++ G+++DE+ Sbjct: 487 TSSATQG-NVV-TQLSNQQQSISGVNLDEE 514
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 30.8 bits (69), Expect = 0.004 Identities = 13/56 (23%), Positives = 24/56 (42%), Gaps = 3/56 (5%) Query: 40 ARRSGIDRIPSMAAEVDLPPSTLNALNQWVSRHPSATATWEAWKRPFEMVAPQNLA 95 + + I + S+A +T A+++W+ +P+A T EA LA Sbjct: 274 GKFAVIGGLGSVAGFEK---NTREAVDRWIQENPNAAETVEAVFNVAAAAKVAKLA 326
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 45.0 bits (106), Expect = 1e-06 Identities = 37/210 (17%), Positives = 74/210 (35%), Gaps = 23/210 (10%) Query: 1435 VLITGGTGTLGRALARHLVAKHGVRHLLLVSRSGAAAPEATALVEELAEQGTATTVAACD 1494 ITG +G A+AR L ++ G ++ + +V L + D Sbjct: 11 AFITGAAQGIGEAVARTLASQ-GAH----IAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 1495 VADPQALAQLLDGLPAR-HPLTAVFHVAGVIEPAPLLQLTPAQLEAV----VRPKLDAAW 1549 V D A+ ++ + P+ + +VAGV+ P + L+ + EA +A+ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 1550 QLHLQTRHRNLAAFVLYSSAAGLLPQPGQSHYAAANTFLDALAHH----------RRHLG 1599 + R + V S +P+ + YA++ R ++ Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 1600 LPA---VALAWGLWAERSAMGERMAAAGIQ 1626 P + W LWA+ + + + + Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLET 215
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.2 bits (159), Expect = 9e-15 Identities = 27/136 (19%), Positives = 53/136 (38%), Gaps = 4/136 (2%) Query: 1 MPSSSILLIDDHVLFRSSVALMLEIRLPVGTTVSEASRIEQALAQ-ALPAPDLILLDLQL 59 M ++IL+ DD R+ + L G V S A DL++ D+ + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRA---GYDVRITSNAATLWRWIAAGDGDLVVTDVVM 57 Query: 60 ESANGLEGIALLQERWPLARVVIVSAFDRDAIVCEAIQRGAVEFHSKTECPEHLLQRIQA 119 N + + +++ P V+++SA + +A ++GA ++ K L+ I Sbjct: 58 PDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117 Query: 120 LLSGEPPEPRTIASTP 135 L+ P + Sbjct: 118 ALAEPKRRPSKLEDDS 133
>PF06580#Sensor histidine kinase Length = 349 Score = 35.2 bits (81), Expect = 4e-04 Identities = 51/260 (19%), Positives = 92/260 (35%), Gaps = 70/260 (26%) Query: 219 ETAKRARRDLQQLRIALQRARQSNTARCQLLAGASHDLRQPLQAQ---GFFLAALAGSPL 275 + K+A D ++ Q A QL+A L+AQ F AL Sbjct: 142 KNYKQAEIDQWKMASMAQEA--------QLMA---------LKAQINPHFMFNALNN--- 181 Query: 276 DPQQRQLLVRARTAVKTTTDMLNTLLDLSRIELGALQPTLQVFALQPLLDKLE-----ME 330 + +ML +L +L R L L D+L ++ Sbjct: 182 ------IRALILEDPTKAREMLTSLSELMRYSLRYSNA-----RQVSLADELTVVDSYLQ 230 Query: 331 LAPLANGKGLSYR-TLDTELLSLSDPTLLELILRNLIGNAIRYTLR-----GGVLIACQR 384 LA + L + ++ ++ + P + +++ L+ N I++ + G +L+ + Sbjct: 231 LASIQFEDRLQFENQINPAIMDVQVPPM---LVQTLVENGIKHGIAQLPQGGKILLKGTK 287 Query: 385 RHGYLQIEVVDTGVGIALQHQQEIFRDFHQLDHPTRNNHEGLGLGLAIV-ARLARLLG-- 441 +G + +EV +TG +N E G GL V RL L G Sbjct: 288 DNGTVTLEVENTGSLAL------------------KNTKESTGTGLQNVRERLQMLYGTE 329 Query: 442 HPLTLASREGHGSTFRVHLP 461 + L+ ++G V +P Sbjct: 330 AQIKLSEKQG-KVNAMVLIP 348
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 25.7 bits (56), Expect = 0.015 Identities = 10/42 (23%), Positives = 19/42 (45%), Gaps = 1/42 (2%) Query: 17 PVENDEDIFDLGANSLTAIQLIGQVNEAFGANINMEQFFLTP 58 + + ED+ D G +S+ + L+ Q GA + + P Sbjct: 249 DITDQEDLLDRGLDSVRIMTLVEQWRRE-GAEVTFVELAERP 289
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 29.3 bits (65), Expect = 0.029 Identities = 18/60 (30%), Positives = 27/60 (45%) Query: 318 SFTNYLLPVFSYSDISPGHAKKIQAQAEKSQKRMGIVFDTAFFSPDLKTQRLALGMLRED 377 S+ NY+ P+ SD S G + AE K+M T+ D T+ L + +ED Sbjct: 367 SYVNYVSPLKVISDPSTGIVSSKKNNAEMKSKQMSTDQMTSEKEFDYYTETLKALLEKED 426
>PF06704#DspF/AvrF protein Length = 129 Score = 28.3 bits (63), Expect = 0.005 Identities = 19/94 (20%), Positives = 36/94 (38%), Gaps = 5/94 (5%) Query: 28 QWQEGMDITLHVSGDSLTLLAKIIELRTDPKDDILLRKLLTHTFPGLRLRRGALTINPDE 87 Q E I + + + ++ P L+KLL+ F R+ + D+ Sbjct: 36 QDNEAAVIEMPDHSEMVIFHCRVGR---SPDRAADLQKLLSLNFDVARMHGSWFAV--DQ 90 Query: 88 SALVFSYEHDFHLLDKARFESLLANFAETAQELR 121 + + + +LD+A+F F A+E R Sbjct: 91 GDVRLCAQRELAVLDEAQFCDTARGFIVQAREAR 124
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 33.3 bits (76), Expect = 0.002 Identities = 15/79 (18%), Positives = 33/79 (41%), Gaps = 4/79 (5%) Query: 291 AMITELKRTKSLTLVDANYVKGKKSNPQTTELKNLNVRSEREVVTEAGATYRRVAITDHN 350 ++I ELK T +++ K + L R +++ + + Y R+ +TD Sbjct: 10 SIIDELKNT----IINGKIDKVNQPEKDEIILNIRKGRLSFKLLISSSSNYPRIHLTDLT 65 Query: 351 RPSPEATDELVDIMRHCLQ 369 +P+P ++R + Sbjct: 66 KPNPIKAPMFCMVLRKYIS 84
>PERTACTIN#Pertactin signature. Length = 922 Score = 33.2 bits (75), Expect = 0.005 Identities = 20/54 (37%), Positives = 23/54 (42%), Gaps = 4/54 (7%) Query: 589 APPAAKPQLSRQAQPVQARTVQTPQPRQTQPQGQAQQRTPLSPRPHSTVPPHGQ 642 APPA KP QP P+ QP Q QR P +P P PP G+ Sbjct: 567 APPAPKPAPQPGPQPGPQPPQPPQPPQPPQPP-QPPQRQPEAPAPQ---PPAGR 616
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.7 bits (207), Expect = 5e-22 Identities = 26/107 (24%), Positives = 42/107 (39%), Gaps = 3/107 (2%) Query: 6 TRQQLLLVDDEEDANEELAELLEGEGFCCFTASSVKMALHQLTAHPDIALVITDLRMPEE 65 T +L+ DD+ L + L G+ S+ + A LV+TD+ MP+E Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-GDLVVTDVVMPDE 60 Query: 66 SGIQLIRHLREHTSRQHLPVIVTSGHADMDDVSDMLRLHVLDLFRKP 112 + L+ +++ R LPV+V S D KP Sbjct: 61 NAFDLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKP 105
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 140 bits (354), Expect = 2e-38 Identities = 72/255 (28%), Positives = 114/255 (44%), Gaps = 16/255 (6%) Query: 134 PSQVQTDIRFVEVSRTRLKEASISIFGKGSNNFLFGAPGTVPGVTV-------TPGTVSG 186 QV + EV I K + F G + GTVS Sbjct: 344 RPQVLVEAIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSS 403 Query: 187 TLPSIPLNNGNFNIVWGGGSSKVLGM-LNAMENSGYAYTLARPSLVALNGQSASFLAGGE 245 +L S +FN + G M L A+ +S LA PS+V L+ A+F G E Sbjct: 404 SLAS---ALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQE 460 Query: 246 FPVPVPNGEGNG----ISIEYKEFGVRLTLTPTIVGRDRILLKVAPEVSELDFSAGITIA 301 PV + +G ++E K G++L + P I D +LL++ EVS + +A + + Sbjct: 461 VPVLTGSQTTSGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAAS-STS 519 Query: 302 GTTVPALNIRRTDTSIALADGESFVVSGLISSSNVGAVDKFPGLGDIPILGAFFRSSQIQ 361 N R + ++ + GE+ VV GL+ S DK P LGDIP++GA FRS+ + Sbjct: 520 SDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKK 579 Query: 362 RNERELLMIVTPHLV 376 ++R L++ + P ++ Sbjct: 580 VSKRNLMLFIRPTVI 594
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.5 bits (74), Expect = 0.003 Identities = 19/106 (17%), Positives = 36/106 (33%), Gaps = 2/106 (1%) Query: 22 LQSALGSLGQVVSAGTGSLDDLLALVDVTFASVVFVGLDREHLMTQSALIESALEAKPML 81 L AL G V T + L + +V + L+ +A+P L Sbjct: 19 LNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDV-VMPDENAFDLLPRIKKARPDL 76 Query: 82 AIVALGDGMDNQLVLNAMRAGARDFVAYGSRSSEVAGLVRRLSKRL 127 ++ + + A GA D++ +E+ G++ R Sbjct: 77 PVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>PF06580#Sensor histidine kinase Length = 349 Score = 33.3 bits (76), Expect = 0.002 Identities = 25/144 (17%), Positives = 47/144 (32%), Gaps = 25/144 (17%) Query: 104 LLQLIGWGSFEIIVMRDAASLLGARAFANESLWANPVLWTLLFGALATLL--AISGPL-- 159 Q IGWG + + F SL+ +P L +++F +L+ ++ Sbjct: 14 YCQGIGWGVYTLT------------GFGFASLYGSPKLHSMIFNIAISLMGLVLTHAYRS 61 Query: 160 TFVRRFLRQWG----LWILLAACS-----WLTWNLLAKADLATLWSTSGDGTMQFASGFD 210 R+ + + +L AC W N LA + + T+ A Sbjct: 62 FIKRQGWLKLNMGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLALSII 121 Query: 211 IAIAMPLSWLPLIADYSRFGRRAK 234 + + L+ F + K Sbjct: 122 FNVVVVTFMWSLLYFGWHFFKNYK 145
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 44.4 bits (105), Expect = 2e-06 Identities = 37/167 (22%), Positives = 61/167 (36%), Gaps = 33/167 (19%) Query: 638 VFAHTQISAAELKLASCVLIVLLLIAPFGFNGALRVV---ALPLLAALCSLASLGWLGQP 694 F I L +++V L++ F N ++ A+P+ L + A L G Sbjct: 331 PFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPV-VLLGTFAILAAFGYS 389 Query: 695 LTLFSLFGLLLVTAISVDYAILMRE----------------------QIGGAAVSLLGTL 732 + ++FG++L + VD AI++ E QI GA V + L Sbjct: 390 INTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVL 449 Query: 733 LAAVTTWLSFGLLAISGTPAISNFGLSVSLGLAFSFLLA----PWAS 775 A FG S F +++ +A S L+A P Sbjct: 450 SAVFIPMAFFG---GSTGAIYRQFSITIVSAMALSVLVALILTPALC 493 Score = 36.0 bits (83), Expect = 7e-04 Identities = 33/146 (22%), Positives = 59/146 (40%), Gaps = 14/146 (9%) Query: 268 ILLLLLLAFRRWSVLLAFVPVVVGMLFGAVACVALFG-SMHVMTLVLGSSLIGVAVDYP- 325 ++ L L R + VPVV L G A +A FG S++ +T+ IG+ VD Sbjct: 354 VMYLFLQNMRATLIPTIAVPVV---LLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAI 410 Query: 326 -----LHYLSKSWSMKPW----RSWPALRLTLPGLSLSLITSCIGYLALAWTPFPALTQI 376 + + + P +S ++ L G+++ L I + Q Sbjct: 411 VVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQF 470 Query: 377 AVFSAAGLIGAYLTAVCLLPALLARV 402 ++ + + + L A+ L PAL A + Sbjct: 471 SITIVSAMALSVLVALILTPALCATL 496 Score = 32.1 bits (73), Expect = 0.012 Identities = 18/70 (25%), Positives = 29/70 (41%), Gaps = 1/70 (1%) Query: 651 LASCVLIVLLLIAPFGFNGALRVVALPL-LAALCSLASLGWLGQPLTLFSLFGLLLVTAI 709 S V++ L L A + V L + L + L + Q ++ + GLL + Sbjct: 877 AISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGL 936 Query: 710 SVDYAILMRE 719 S AIL+ E Sbjct: 937 SAKNAILIVE 946
>PERTACTIN#Pertactin signature. Length = 922 Score = 29.3 bits (65), Expect = 0.023 Identities = 18/60 (30%), Positives = 23/60 (38%), Gaps = 5/60 (8%) Query: 236 GQWMLQHEEA-----LRRHPDLQNAGPRRGALDKPESPPPPPPPNRRADEPEPKKPLGMA 290 GQW L +A P Q P+ P PP PP R+ + P P+ P G Sbjct: 558 GQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGRE 617
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 273 bits (699), Expect = 6e-91 Identities = 103/293 (35%), Positives = 149/293 (50%), Gaps = 8/293 (2%) Query: 25 RAKALVFIDPRSRRLREEMEQLAPRELPVLIRGESGTGKELLARHIHRGSDRS-GLFVSV 83 LV + + + +L +L ++I GESGTGKEL+AR +H R G FV++ Sbjct: 135 DGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAI 194 Query: 84 NCGAISPTYADAELFGYAAGAHSGSVSSRAGWFGSANGGTLYLDEIGDLPLPIQVKLLAA 143 N AI ++ELFG+ GA +G+ + G F A GGTL+LDEIGD+P+ Q +LL Sbjct: 195 NMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRV 254 Query: 144 LENHEVTRVGAHQPSPVDVRLVAATSIDLAQAVAAGKFHERLYHYLSEGKLDLPALREQP 203 L+ E T VG P DVR+VAAT+ DL Q++ G F E LY+ L+ L LP LR++ Sbjct: 255 LQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRA 314 Query: 204 GNILPLAEYFVGIYSQRLSLPVQLISEDAQRTLEAHSWPGNTRELENVIHFALLVSSGDE 263 +I L +FV + L V+ ++A ++AH WPGN RELEN++ + D Sbjct: 315 EDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDV 373 Query: 264 IRAEDINLPDIATPLTLIERQAKLLVSSGDREQLSALRQLLESVTSQLEQSPA 316 I E I E + + R ++ Q +E Q S Sbjct: 374 ITREIIENE------LRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFG 420
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 38.7 bits (90), Expect = 4e-05 Identities = 30/143 (20%), Positives = 50/143 (34%), Gaps = 3/143 (2%) Query: 28 LSVAAPTLMSELSISTEQYAHIVVAWQLCYAIMQPVAGYIIDAIGTKMGFAIFAVAWSGA 87 L+V+ P + ++ + + A+ L ++I V G + D +G K + Sbjct: 33 LNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFG 92 Query: 88 CAAAAFATGWQSLAIFRGLLGLTEAAGLPAGVK-ATTEWFPAKERSVAIGWFNIGSSFGA 146 + SL I + AA PA V + P + R A G + G Sbjct: 93 SVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGE 152 Query: 147 LLAPPLVVWAILHS-GWELAFLI 168 + P + I H W LI Sbjct: 153 GVG-PAIGGMIAHYIHWSYLLLI 174
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 23.7 bits (51), Expect = 0.038 Identities = 11/42 (26%), Positives = 21/42 (50%) Query: 2 KRKLDLLWILVVLFGLGVVTTGYAQSLWTSKDDAPVEITQQQ 43 +R LL I+VV+ +GV+ + +L +K+ A + Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSD 48
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 245 bits (626), Expect = 1e-74 Identities = 167/539 (30%), Positives = 259/539 (48%), Gaps = 45/539 (8%) Query: 156 YLLASASLPNDLQKEIASGHDLNADPPRDEQTLELILQKKTR-VNYLLAIKQPLLDERRA 214 + A L +Q E+ A P ++ + V L K L + Sbjct: 82 FRDAEKKLEASVQAELDKAD--AALGPAKNLAPLDVINRSLTIVGNALQQKNQKLLLNQK 139 Query: 215 QALSLTGQELDHATQKDHLNYLVYYSQGDPPRV-QQAHEAWVNALSQTYEAKLLAESVT- 272 + SL + T ++ V + P + + + L+ Y KL E+++ Sbjct: 140 KITSLGAKNFLTRTAEEIGEQAVREGNINGPEAYMRFLDREMEGLTAAYNVKLFTEAISS 199 Query: 273 ---LLNEQSAALSMRHAELS-LANKPASQEARQAAGIDKLWSVIAPASTTTAAPGIRTVA 328 +N +AA + A + A + A+ EA++ A A+ T A P +V Sbjct: 200 LQIRMNTLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAANTYAMPANGSVV 259 Query: 329 TNIAKDQLIRIA--TRTLGSNLVTLLAMYPQPLGDA----------------------EL 364 A LI++A +L + +A+ + L A + Sbjct: 260 ATAAGRGLIQVAQGAASLAQAISDAIAVLGRVLASAPSVMAVGFASLTYSSRTAEQWQDQ 319 Query: 365 PP----AVIATPLSQLNLPPHIDLHYLASVKGTLDVPHRLTSDEAGTSAT-RWVATDGVK 419 P + ++L LPP ++L+ +A GT+D+P RLT++ G + T V+TDGV Sbjct: 320 TPDSVRYALGMDAAKLGLPPSVNLNAVAKASGTVDLPMRLTNEARGNTTTLSVVSTDGVS 379 Query: 420 VGTKVRVRTFTYNAQNNSYE--FIRDGESTPALI--WTPIAQPA--DSSTSSPAGPPALP 473 V V VR YNA YE P LI WTP + P + S+++P P +P Sbjct: 380 VPKAVPVRMAAYNATTGLYEVTVPSTTAEAPPLILTWTPASPPGNQNPSSTTPVVPKPVP 439 Query: 474 VDPGNVVTPFVPELEAYPAIDRDDPDDYILISPIDSGLPNTYLLFKDPRSIPGVASGYGE 533 V G +TP E YP + P+D I+ P DSG+ Y++F+DPR +PG A+G G+ Sbjct: 440 VYEGATLTPVKATPETYPGVITL-PEDLIIGFPADSGIKPIYVMFRDPRDVPGAATGKGQ 498 Query: 534 PVTGVWLGDRTRAEGASIPTHIADQLRGRRFGDFASLRKATWIAVADDPELGKQSTQNNL 593 PV+G WLG ++ EGA IP+ IAD+LRG+ F ++ R+ WIAVA+DPEL KQ +L Sbjct: 499 PVSGNWLGAASQGEGAPIPSQIADKLRGKTFKNWRDFREQFWIAVANDPELSKQFNPGSL 558 Query: 594 EIMRGGGAPHPKLSDQAGGRTRFEIHHKNYISKGGAVYDIDNLVIMTSRQHIDHHRSQK 652 +MR GGAP+ + S+QAGGR + EIHHK ++ GG VY++ NLV +T ++HI+ H+ K Sbjct: 559 AVMRDGGAPYVRESEQAGGRIKIEIHHKVRVADGGGVYNMGNLVAVTPKRHIEIHKGGK 617
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 174 bits (442), Expect = 9e-54 Identities = 81/361 (22%), Positives = 148/361 (40%), Gaps = 58/361 (16%) Query: 1 MRILVTGGAGFIGSALIRHLINNTEHDVLNFDKLT--YAGNL-ESLQSIASNTRYEFVHA 57 M+ LVTG AGFIG + + L+ H V+ D L Y +L ++ + + ++F Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DICDQAKVSAVLERFAPQAIMHLAAESHVDRSIDGPAEFVQTNIVGTYSLLEATRAYWLK 117 D+ D+ ++ + + + V S++ P + +N+ G ++LE R Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN--- 116 Query: 118 LPDVERQAFRFHHISTDEVYGDLHGVDDLFTETTPYA-------PSSPYSASKAASDHLV 170 ++ + S+ VYG P++ P S Y+A+K A++ + Sbjct: 117 --KIQHLLYA----SSSSVYGL--------NRKMPFSTDDSVDHPVSLYAATKKANELMA 162 Query: 171 RAWHRTYGLPVVVTNCSNNYGPFHFPEKLIPLVILNALAGKPLPVYGNGLQVRDWLYVED 230 + YGLP YGP+ P+ + L GK + VY G RD+ Y++D Sbjct: 163 HTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDD 222 Query: 231 HARALLKVV-------TEGDVG-----------ETYNIGGHNEQKNIDVVRGICSLLDEL 272 A A++++ T+ V YNIG + + +D ++ + L Sbjct: 223 IAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALG-- 280 Query: 273 APQHPDGVQHYSDLITYVVDRPGHDQRYAIDASKIDNELGWTPEETFESGLRKTVQWYLD 332 + ++ L +PG + D + +G+TPE T + G++ V WY D Sbjct: 281 ----IEAKKNMLPL------QPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRD 330 Query: 333 N 333 Sbjct: 331 F 331
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 30.4 bits (68), Expect = 0.022 Identities = 42/201 (20%), Positives = 84/201 (41%), Gaps = 21/201 (10%) Query: 312 AFEAKARRELEM-RVIERTSD-------LEGLNSRLRQEVLEREQAQQELVQAQDELVQT 363 AF+ +R E+ R T E + L +E E AQ++L AQ E+V+ Sbjct: 149 AFQEAEQRRKEIEREKAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKM 208 Query: 364 SKLTALGTMSASISHELNQPLAAIRSYA----ENAEVLLDHQRTEEARGNLKLISE--LT 417 + T+++ +S ++ A +++ A E A+ ++ +E L + L Sbjct: 209 D--GEIKTLNSRLSSSIHARDAEMKTLAGKRNELAQASAKYKELDELVKKLSPRANDPLQ 266 Query: 418 GRMA--SIIAHLRAFARRDRHAPESVALQPALDDALALLTKRRRAM-EVELIRDLPDATL 474 R + + A R+ + A + ++ A +T+ ++A+ +V R+ A Sbjct: 267 NRPFFEATRRRVGAGKIREEKQKQVTASETRINRINADITQIQKAISQVSNNRNAGIAR- 325 Query: 475 WVQAGETRLRQVLGNLLANAL 495 V E L++ NLL + + Sbjct: 326 -VHEAEENLKKAQNNLLNSQI 345
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 36.3 bits (83), Expect = 1e-04 Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 12/109 (11%) Query: 156 WRELRDIALSLLDALAYSHARGVLHGDMKPSNVMLSEEGVRLFDFGLGQAEEGVMPGLPH 215 W ++ IA LLD + GV+H D+KP NV +FD G+ + GL Sbjct: 244 WGTIKFIAHRLLDVTNHLAKAGVVHNDIKPGNV--------VFDRASGEPVV-IDLGLHS 294 Query: 216 LSRERFNAWTPGYAAPELLEGQ-ALSASADVYGVACVIFELAGG--KHP 261 S E+ +T + APEL G S +DV+ V + G K+P Sbjct: 295 RSGEQPKGFTESFKAPELGVGNLGASEKSDVFLVVSTLLHCIEGFEKNP 343
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 400 bits (1030), Expect = e-138 Identities = 143/374 (38%), Positives = 204/374 (54%), Gaps = 36/374 (9%) Query: 162 SFALGQLNLLQRLHKPADEVRPAGITMPSVSGYGLIGKSASMRQTYTMISKVLHSPYTVL 221 F L +L + + RP+ + S G L+G+SA+M++ Y ++++++ + T++ Sbjct: 105 PFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLM 164 Query: 222 LRGETGTGKEVVARAIHDFGPRRSQPFIVQNCAAFPEHLLESELFGYRKGAFTGADSDRT 281 + GE+GTGKE+VARA+HD+G RR+ PF+ N AA P L+ESELFG+ KGAFTGA + T Sbjct: 165 ITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRST 224 Query: 282 GLFEAANGGTLLLDEIGDIPLPLQAKLLRVLQEGEIRPLGCNDTRKIDVRILAATHRDLS 341 G FE A GGTL LDEIGD+P+ Q +LLRVLQ+GE +G + DVRI+AAT++DL Sbjct: 225 GRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLK 284 Query: 342 AMVSEGKFREDLYYRLAQFPIELPALRNREGDILDLARHFVDKTCAFLQRSPLRWSDAAL 401 +++G FREDLYYRL P+ LP LR+R DI DL RHFV + R+ AL Sbjct: 285 QSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEK-EGLDVKRFDQEAL 343 Query: 402 DLLSGYTFPGNVRELKGLVERAVLLCEGSELLVEHFSLR--------------------- 440 +L+ + +PGNVREL+ LV R L + E Sbjct: 344 ELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLS 403 Query: 441 -PEVVPEGSSLN-------------LRERLEQVERSLLLDCLRKNDGNQTLSARELGLPR 486 + V E L ++E L+L L GNQ +A LGL R Sbjct: 404 ISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNR 463 Query: 487 RTLLYRLGRLNINL 500 TL ++ L +++ Sbjct: 464 NTLRKKIRELGVSV 477
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.039 Identities = 43/250 (17%), Positives = 74/250 (29%), Gaps = 29/250 (11%) Query: 463 RVALEAMWLEQKTLAERLLELRQQLAKAREAVAAVPVVEIGEDDEGTVIEAVALDETQSV 522 AL + + L + +A + VV E+ + V Sbjct: 20 NQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKARPDLPV 78 Query: 523 EALTAALNDTHVALAALQVKERLVSFEVCPRLVAEVISAWTGVPLAQLAREHNAKVASFA 582 ++A N A+ A ++ + P + E+I + A + Sbjct: 79 LVMSA-QNTFMTAIKAS--EKGAYDYLPKPFDLTELIGI---IGRALAEPKRRPSKLEDD 132 Query: 583 KDLRIRIRGQEQAVHALDRSMRATAAGLNKPDAPVGVFLLVGPSGVGKTETALALADLLY 642 + + G+ A+ + R + D + ++ G SG GK A AL D Sbjct: 133 SQDGMPLVGRSAAMQEIYRVLARLMQT----DLTL---MITGESGTGKELVARALHDYGK 185 Query: 643 GGDRFITTINMSEFQEKHTVSRLIGAPPGYVGYGEGGMLTEAVRQKPYSV-------VLL 695 + INM+ S L G E G T A + + L Sbjct: 186 RRNGPFVAINMAAIPRDLIESELFGH--------EKGAFTGAQTRSTGRFEQAEGGTLFL 237 Query: 696 DEVEKADPDV 705 DE+ D Sbjct: 238 DEIGDMPMDA 247
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 29.9 bits (66), Expect = 0.019 Identities = 39/150 (26%), Positives = 65/150 (43%), Gaps = 9/150 (6%) Query: 167 VNRSAVALTAA-RDLDTILVARPELIGADSQAAERRERLRGDLVRGINQRLAELNATGMG 225 +NR L A +D D + VA +L + E + +L+ N +++ +G Sbjct: 192 LNRQLTHLAAGTKDTDAVNVA--QLKKEIEKTQENTNKRSAELLANANAYADNKSSSVLG 249 Query: 226 IGVEVARVDVQSSLPKAAVNAF---NAVLTASQQADQAVANARTEAEKLTQTANQQADRT 282 I +L A AF VL ++ +VA RT E + AN A T Sbjct: 250 IANNYTDSKSAETLENARKEAFAQSKDVLNMAKAHSNSVA--RTTLETAEEHANSVARTT 307 Query: 283 LQVAHAQASERLAKAQAATATVVSLSESAQ 312 L+ A A+++ A+A A+A V + S+S+ Sbjct: 308 LETAEEHANKKSAEA-LASANVYADSKSSH 336
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 30.3 bits (68), Expect = 0.008 Identities = 35/168 (20%), Positives = 63/168 (37%), Gaps = 31/168 (18%) Query: 40 PQRAVSNDVNLTKMMVALGLQSHMVGYSGITGWNK-----PDQALLHDLGNLPELASKYP 94 P R V+ + ++++ALG+ G + + P + D+G E P Sbjct: 35 PNRIVALEWLPVELLLALGIVP--YGVADTINYRLWVSEPPLPDSVIDVGLRTE-----P 87 Query: 95 SLETLLNANADFYFAGWNYGMRVGGDVTPQSLA---PLGIQAYELTESCAQIMPRAEATL 151 +LE L F YG +P+ LA P + + + ++ + Sbjct: 88 NLELLTEMKPSFMVWSAGYG------PSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEM 141 Query: 152 ADVYNDLLNLGRIFDVQTRAETLVAQMRRSVSDVQANVAGKTSPRVFL 199 AD LLNL Q+ AET +AQ + ++ + + + L Sbjct: 142 AD----LLNL------QSAAETHLAQYEDFIRSMKPRFVKRGARPLLL 179
>PF06580#Sensor histidine kinase Length = 349 Score = 30.6 bits (69), Expect = 0.014 Identities = 20/99 (20%), Positives = 36/99 (36%), Gaps = 21/99 (21%) Query: 38 RAAEQNIEQNSLPSIQVIDDIQIALLHAR---------LESIRMLASTDPDVKKASEAKV 88 + I+Q + S+ + Q+ L A+ L +IR L DP Sbjct: 143 NYKQAEIDQWKMASMA--QEAQLMALKAQINPHFMFNALNNIRALILEDPT--------- 191 Query: 89 RQAMDTLQSRSDFYQKNLISGEQDRSQFDDARNKMSNYL 127 +A + L S S+ + +L + D + +YL Sbjct: 192 -KAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYL 229
>STREPTOPAIN#Streptopain (C10) cysteine protease family signature. Length = 398 Score = 30.4 bits (68), Expect = 0.011 Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 4/55 (7%) Query: 185 LEDIHRLDTEIKACDAQIKQQLAQDDAGTRLMTIPGIGPITASAFVADLGDASNF 239 + I+R D + +AQI ++L+Q+ + + G+G + AFV D D NF Sbjct: 302 VHQINRGDFSKQDWEAQIDKELSQN----QPVYYQGVGKVGGHAFVIDGADGRNF 352
>SSBTLNINHBTR#Streptomyces subtilisin inhibitor signature. Length = 144 Score = 25.6 bits (55), Expect = 0.040 Identities = 11/46 (23%), Positives = 19/46 (41%), Gaps = 1/46 (2%) Query: 56 PPAFIPLAMPPAGANPHPASPNICVEIQHTRGTVKVSWPTENAAAC 101 P + L P + HPA+ C E++ G + E++ C Sbjct: 58 PLRAVTLTCAPTASGTHPAAAAACAELRAAHGDPS-ALAAEDSVMC 102
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 29.6 bits (66), Expect = 0.041 Identities = 28/104 (26%), Positives = 42/104 (40%), Gaps = 5/104 (4%) Query: 550 NADKTDKKAQRQQAAALRQQLAPHKREADKLERDLGLVNEKLAKVEEALA----DSTNYE 605 +A + KK + L +Q + L RDL E ++E + E Sbjct: 319 DASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISE 378 Query: 606 AANKDKLRDLLAEQAKLKVRESELEDAWMQALELLESMQAELEA 649 A+ + RDL A + K E LE+A + L LE + ELE Sbjct: 379 ASRQSLRRDLDASREAKKQVEKALEEANSK-LAALEKLNKELEE 421
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 31.2 bits (70), Expect = 0.013 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 5/95 (5%) Query: 41 LGADYPASVADGKVVEAADYQ--QQIEALTTLQGLVLALPQRAERADLEQAVAQLKNAVS 98 L D AS K VE A + ++ AL L + + E+ E+A Q K Sbjct: 384 LRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEK---EKAELQAKLEAE 440 Query: 99 SKQDGTQVARQARQLAAKLAVAYEVSQAPAITPDP 133 +K ++A+QA +LA A SQ P P Sbjct: 441 AKALKEKLAKQAEELAKLRAGKASDSQTPDAKPGN 475
>OUTRSURFACE#Outer surface protein signature. Length = 273 Score = 31.8 bits (72), Expect = 0.009 Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 10/64 (15%) Query: 547 DDLSRLTAETDPLGRTTRFKHHYKTTLVKQVTYPDGSTWQARYDDRGNLITEI--DALGN 604 DDLS+ T E FK KT + ++V+ D ++ ++++G L + G Sbjct: 92 DDLSKTTFEL--------FKEDGKTLVSRKVSSKDKTSTDEMFNEKGELSAKTMTRENGT 143 Query: 605 KTEY 608 K EY Sbjct: 144 KLEY 147
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 797 bits (2061), Expect = 0.0 Identities = 229/1061 (21%), Positives = 440/1061 (41%), Gaps = 55/1061 (5%) Query: 5 LIQFAIEQRIVVMLAVLLMAGLGIASYQKLPIDAVPDITNVQVQINTSAPGFSPLETEQR 64 + F I + I + +++ G + +LP+ P I V ++ + PG + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 65 VTFAIETNMAGLPGLQQTRSLSRS-GLSQVTVIFEDGTDLFFARQLVGERLQIAKDQLPE 123 VT IE NM G+ L S S S G +T+ F+ GTD A+ V +LQ+A LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 124 GVDAMMGPISTGLGEIFLWTVEARDGALKEDGTPYTPTDLRVIQDWIIKPQLRNVPGVAE 183 V + +L D T D+ +K L + GV + Sbjct: 121 EVQQQGISVEKSSS-SYLMVA-----GFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGD 174 Query: 184 INTIGGFAKQYQIAPDPKKLAAYKLTLNDLVAALERNNANVGAGYIERGGE------QLL 237 + G +I D L YKLT D++ L+ N + AG + Sbjct: 175 VQLFGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNAS 233 Query: 238 IRAPGQLGTVDDIANIVI-ANVQGTPIRISSVAEVGIGKEMRSGAATENGREVVLGTVFM 296 I A + ++ + + N G+ +R+ VA V +G E + A NG+ + + Sbjct: 234 IIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKL 293 Query: 297 LIGENSRTVSQAVAAKLADINRTLPEGVEAVTVYDRTNLVEKAIATVKKNLIEGAILVIV 356 G N+ ++A+ AKLA++ P+G++ + YD T V+ +I V K L E +LV + Sbjct: 294 ATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFL 353 Query: 357 ILFLFLGNIRAALITAMVIPLAMLFTFTGMFTNKVSANLMSLG--ALDFGIIVDGAVVIV 414 +++LFL N+RA LI + +P+ +L TF + S N +++ L G++VD A+V+V Sbjct: 354 VMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVV 413 Query: 415 ENAIRRLAHAQKKYGRMLTRSERFHEVFAAAREARRPLIFGQLIIMVVYLPIFALTGVEG 474 EN R + + + + + L+ +++ V++P+ G G Sbjct: 414 ENVERVMMEDK---------LPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTG 464 Query: 475 KMFHPMAFTVVIALLGAMILSVTFVPAAIAMFVTGKVKEEE----GFVMRTAR------Q 524 ++ + T+V A+ ++++++ PA A + E GF Sbjct: 465 AIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVN 524 Query: 525 RYAPILSWVLSHRAIAFGMAFVLIVLSGFTASRMGSEFIPSLSEGDFALQALRVPGTSLS 584 Y + +L + +++ R+ S F+P +G F G + Sbjct: 525 HYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQE 584 Query: 585 QSVD-MQQRLEKAIIEKVPEVQRVFARTGTAEIAADPMPPNISDSYVMLKPQSEWPDPDK 643 ++ + Q + + + V+ VF G + N ++V LKP E + Sbjct: 585 RTQKVLDQVTDYYLKNEKANVESVFTVNG---FSFSGQAQNAGMAFVSLKPWEERNGDEN 641 Query: 644 SRETLIADLQKAAASVPGSNYELSQPIQLRFNELVSGVRSDVA-VKVFGDDMNVLNQTAA 702 S E +I + + EL + D + G + L Q Sbjct: 642 SAEAVIHRAKMELGKIRDGFVIPFNM--PAIVELGTATGFDFELIDQAGLGHDALTQARN 699 Query: 703 KIAATLQKVPGA-SEVKVEQTTGLPVLTINIDRDKAARYGLNVADVQDAIAIALGGRQAG 761 ++ + P + V+ + +D++KA G++++D+ I+ ALGG Sbjct: 700 QLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVN 759 Query: 762 TLYEGDRRFDMVVRLSEQLRTDVDGLSSLLIPVPANASSQQISFIALSQVASLDLVLGPN 821 + R + V+ + R + + L + +A+ + + S + V G Sbjct: 760 DFIDRGRVKKLYVQADAKFRMLPEDVDKLYVR---SANGE---MVPFSAFTTSHWVYGSP 813 Query: 822 QISRENGKRVVIVSANVRGRDLGSFVEEAGTTIDS-GVQIPAGYWTNWGGQFEQLQSAAK 880 ++ R NG + + G+ +A +++ ++PAG +W G Q + + Sbjct: 814 RLERYNGLPSMEIQGEAAP---GTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGN 870 Query: 881 RLQIVVPVALLLVLALLFMMFNNLKDGLLVFTGIPFALTGGVMALWLRDIPLSISAGVGF 940 + +V ++ ++V L ++ + + V +P + G ++A L + + VG Sbjct: 871 QAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGL 930 Query: 941 IALSGVAVLNGLVMISFIRSLRE-EGRSLHDAINEGALTRLRPVLMTALVASLGFIPMAL 999 + G++ N ++++ F + L E EG+ + +A RLRP+LMT+L LG +P+A+ Sbjct: 931 LTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAI 990 Query: 1000 ATGTGAEVQRPLATVVIGGILSSTALTLLVLPALYQWAHRR 1040 + G G+ Q + V+GG++S+T L + +P + R Sbjct: 991 SNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031 Score = 88.0 bits (218), Expect = 1e-19 Identities = 71/524 (13%), Positives = 168/524 (32%), Gaps = 40/524 (7%) Query: 2 FERLIQFAIEQRIVVMLAVLLMAGLGIASYQKLPIDAVPDITNVQVQINTSAPGFSPLET 61 + + + +L L+ + + +LP +P+ P + E Sbjct: 526 YTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQER 585 Query: 62 EQRVTFAIETNM-----------AGLPGLQQTRSLSRSGLSQVTV-IFEDGTDLFFARQL 109 Q+V + + G + +G++ V++ +E+ + + Sbjct: 586 TQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEA 645 Query: 110 VGERLQIAKDQLPEG-VDAMMGPISTGLGEIFLWTVEARDGALKEDGTPYTPTDLRVIQD 168 V R ++ ++ +G V P LG D L ++ Sbjct: 646 VIHRAKMELGKIRDGFVIPFNMPAIVELG------TATGFDFELIDQAGLGHDALTQARN 699 Query: 169 WIIKPQLRNVPGVAEINTIG-GFAKQYQIAPDPKKLAAYKLTLNDLVAALERNNANVGAG 227 ++ ++ + + G Q+++ D +K A ++L+D+ + Sbjct: 700 QLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVN 759 Query: 228 YIERGGEQ--LLIRAPGQL-GTVDDIANIVIANVQGTPIRISSVAEVGIGKEMRSGAATE 284 G L ++A + +D+ + + + G + S+ G+ Sbjct: 760 DFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTS----HWVYGSPRL 815 Query: 285 NGREVVLGTVFMLIGENSRTVSQAVAAKLADINRTLPEGVEAVTVYDRTNLVEKAIATVK 344 R L ++ + T S A + ++ LP G+ + + Sbjct: 816 E-RYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGI-GYDWTGMSYQERLSGNQAP 873 Query: 345 KNLIEGAILVIVILFLFLGNIRAALITAMVIPLAMLFTFTGMFTNKVSANLMSLGAL--D 402 + ++V + L + + +V+PL ++ ++ + L Sbjct: 874 ALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTT 933 Query: 403 FGIIVDGAVVIVENAIRRLAHAQKKYGRMLTRSERFHEVFAAAREARRPLIFGQLIIMVV 462 G+ A++IVE A + K A R RP++ L ++ Sbjct: 934 IGLSAKNAILIVEFAKDLMEKEGKG---------VVEATLMAVRMRLRPILMTSLAFILG 984 Query: 463 YLPIFALTGVEGKMFHPMAFTVVIALLGAMILSVTFVPAAIAMF 506 LP+ G + + V+ ++ A +L++ FVP + Sbjct: 985 VLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVI 1028
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 39.4 bits (92), Expect = 2e-05 Identities = 22/115 (19%), Positives = 42/115 (36%), Gaps = 13/115 (11%) Query: 110 VTFPGEIRFDEDRTAHVVPRVSGVVESVKVDLGQAVKKGQVLAVIASQQISDQRSELNAA 169 T G++ + P + +V+ + V G++V+KG VL + + ++ Sbjct: 84 ATANGKLTHSGRSKE-IKPIENSIVKEIIVKEGESVRKGDVLLKLTALG---AEADTLKT 139 Query: 170 QRRQELARLTLQR---------EKKLWEDKISAEQDYLQARQDFQEADINLANAR 215 Q ARL R KL E K+ E + ++ +L + Sbjct: 140 QSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQ 194 Score = 37.5 bits (87), Expect = 9e-05 Identities = 39/214 (18%), Positives = 78/214 (36%), Gaps = 22/214 (10%) Query: 154 IASQQISDQRSELNAAQRRQELARLTLQREKKLWEDKISAEQDYLQARQDFQ-EADINLA 212 IA + +Q ++ A EL Q E+ + + +SA+++Y Q F+ E L Sbjct: 249 IAKHAVLEQENKYVEAV--NELRVYKSQLEQ-IESEILSAKEEYQLVTQLFKNEILDKLR 305 Query: 213 NARQKISAIGASLSPS--AGNRYELIAPFDSMVVE-KHLGIGEMVNEASNAFTLS-DLSR 268 I + L+ + + AP V + K G +V A + + Sbjct: 306 QTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDT 365 Query: 269 VWATFGVAPRDLDKVVVGRPVIVSAPDLN----ARVEGKIGYVG--SLLGEQTRAAA-VR 321 + T V +D+ + VG+ I+ + GK+ + ++ ++ V Sbjct: 366 LEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVI 425 Query: 322 VTL-------ANPQGAWRPGLFVSVEVAAEQSSV 348 +++ N G+ V+ E+ SV Sbjct: 426 ISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSV 459
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.6 bits (204), Expect = 1e-20 Identities = 31/119 (26%), Positives = 61/119 (51%), Gaps = 1/119 (0%) Query: 2 RILVVEDEPKTAEYMHQGLTESGYVVDIAATGLDGLYLAQHQAYDVVILDVNLPEMDGWE 61 ILV +D+ ++Q L+ +GY V I + D+V+ DV +P+ + ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLSRLRKT-VNTRIMMVTARGRLEEKVKGLEMGADDYLVKPFEFPELLARVRTLMRRSE 119 +L R++K + +++++A+ +K E GA DYL KPF+ EL+ + + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123
>PF06580#Sensor histidine kinase Length = 349 Score = 38.3 bits (89), Expect = 5e-05 Identities = 33/157 (21%), Positives = 54/157 (34%), Gaps = 36/157 (22%) Query: 315 EVIDLGEEAEKVA---ELFSSSAEDRDITLQVHVAAKVSG---DKLMIQRAISNLLSNAI 368 + L +E V +L S EDR + + + + +++Q L+ N I Sbjct: 214 RQVSLADELTVVDSYLQLASIQFEDR-LQFENQINPAIMDVQVPPMLVQ----TLVENGI 268 Query: 369 RHGLA----GSVITITLDTHEDEVWLAVRNAGDGIDAEHLPRLFDRFYRVHVSRARQQGG 424 +HG+A G I + V L V N G + Sbjct: 269 KHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN------------------TKES 310 Query: 425 TGLGLAIVRSIMSL---HEGQVTVQSEPGQFTTFNLI 458 TG GL VR + + E Q+ + + G+ LI Sbjct: 311 TGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLI 347
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.3 bits (65), Expect = 0.006 Identities = 18/88 (20%), Positives = 34/88 (38%), Gaps = 1/88 (1%) Query: 46 AKTEGNKAEQSGLEKALAEVNANCTETSLLKQREQKVLDAKREVSRRQTDLNKAMDKGDP 105 ++T AE S E E N + + RE +AK V A + Sbjct: 1034 SETTETVAENSKQESKTVEKNEQDATETTAQNREV-AKEAKSNVKANTQTNEVAQSGSET 1092 Query: 106 EKINKRKDKLAESRKELQEAQTDLEKVQ 133 ++ + K + ++ ++A+ + EK Q Sbjct: 1093 KETQTTETKETATVEKEEKAKVETEKTQ 1120
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 34.7 bits (79), Expect = 6e-04 Identities = 30/186 (16%), Positives = 56/186 (30%), Gaps = 24/186 (12%) Query: 31 ADPAPAKDAAAQAPVERAPLLSRSQEDAIALERQLPREDQQQLQAGDESFLALWKPANTD 90 K+ A E+A + + ++ + Q+ + Q E+ +PA + Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPK-----QEQSETVQPQAEPAREN 1149 Query: 91 APQGAVIILPGDAESPDWPDTVGPLRRK----FPDVGWSSLSITLPDAQDNTL--LPREP 144 P V I +++ DT P + V S+ T +N P Sbjct: 1150 DP--TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATT 1207 Query: 145 DAAAGDANAAKPEE-----------TPKDAAAKAPDPAAEAEALAAVATAKAAADEERNK 193 ++ KP+ + A + D + A A + R K Sbjct: 1208 QPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAK 1267 Query: 194 AQAELI 199 AQ + Sbjct: 1268 AQFVAL 1273
>PF06580#Sensor histidine kinase Length = 349 Score = 43.3 bits (102), Expect = 2e-06 Identities = 30/132 (22%), Positives = 58/132 (43%), Gaps = 16/132 (12%) Query: 538 IASAIEWQARRFEARTQIPCLVQVPDNLPALSDARATGMFRILQEALTNVMRHA-----Q 592 + S ++ + +FE R Q Q+ PA+ D + M ++Q + N ++H Q Sbjct: 225 VDSYLQLASIQFEDRLQFE--NQIN---PAIMDVQVPPM--LVQTLVENGIKHGIAQLPQ 277 Query: 593 AHTVEISLTLQDGMMCMTVADDGQGFVVESGRAVSFGLVGMRERVLMLGG---RLELDSE 649 + + T +G + + V + G + + + GL +RER+ ML G +++L + Sbjct: 278 GGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEK 337 Query: 650 AGEGTTLRAYIP 661 G IP Sbjct: 338 QG-KVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.6 bits (160), Expect = 8e-15 Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 2/116 (1%) Query: 2 IRVLVAEDHTIVREGIKQLIGLARDLQVVGEASNGEQLLETLRHVACEVVLLDISMPGVN 61 +LVA+D +R + Q + A V SN L + ++V+ D+ MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLEAIPRIRALTHPPAILVLSMHNEAQMAARALKVGAAGYATKDSDPALLLTAIRR 117 + +PRI+ +LV+S N A +A + GA Y K D L+ I R Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.7 bits (74), Expect = 0.002 Identities = 15/87 (17%), Positives = 26/87 (29%), Gaps = 20/87 (22%) Query: 44 LTLLGPSGSGKTTSLMMLAGFETPTAGEILLGGRAINNVPPHKRDIGMVFQNYALFPHMT 103 + L G G GK+T + L G + + +G +D Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIG---------TGKDSYEQIAGIVA---YE 646 Query: 104 VAENLAFPLSVRGMSKTDVGEKVKKAL 130 ++E + + D E VK Sbjct: 647 LSE-------MTAFRRADA-EAVKAFF 665
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 41.1 bits (96), Expect = 4e-07 Identities = 21/92 (22%), Positives = 40/92 (43%), Gaps = 11/92 (11%) Query: 1 MKHAGFTLIELLIVVALVAILANVATPSFKQLIDSNRGLVAAQELASGIRSARVA---AI 57 M+ GFTL+E+++++ L+ + A + +F ++R AAQ LA R + Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAFP----ASRDDSAAQTLARFEAQLRFVQQRGL 56 Query: 58 TRNQIVTIHAIEEDWSNGWRIILDLDGKGPDE 89 Q + + D W+ ++ G D Sbjct: 57 QTGQFFGVS-VHPD---RWQFLVLEARDGADP 84
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 40.3 bits (94), Expect = 7e-07 Identities = 15/66 (22%), Positives = 36/66 (54%), Gaps = 3/66 (4%) Query: 6 KGFSLIELLVTVSLVGILAAIAIPSFTSSIQSNKADTELSDLQRALNYARLEAI--NRGV 63 +GF+L+E+++ + L+G+ A + + +F +S + A T L+ + L + + + + Sbjct: 4 RGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQT-LARFEAQLRFVQQRGLQTGQFF 62 Query: 64 TVRIAP 69 V + P Sbjct: 63 GVSVHP 68
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 28.3 bits (63), Expect = 0.011 Identities = 10/27 (37%), Positives = 19/27 (70%), Gaps = 2/27 (7%) Query: 5 ARHRQAGMTLIEVLVSVLILAIGLLGA 31 A +Q G TL+E++V ++I+ G+L + Sbjct: 3 ATDKQRGFTLLEIMVVIVII--GVLAS 27
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 31.5 bits (71), Expect = 0.002 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Query: 6 RGFGLVEIMVALVLGLVVSLGIIQIFTASRATYQSQNAAARMQEDARFILSKLIQEIRMT 65 RGF L+E+M+ L+L V + ++ F ASR +Q AR + RF+ + +Q + Sbjct: 4 RGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQT-LARFEAQLRFVQQRGLQTGQFF 62 Query: 66 GMY 68 G+ Sbjct: 63 GVS 65
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 49.1 bits (117), Expect = 2e-10 Identities = 21/66 (31%), Positives = 37/66 (56%), Gaps = 2/66 (3%) Query: 1 MRATS--RGFTLIELMIVVAIVGILAAIAYPSYTEYVKRTQRSAVASLLSEQVQALERFY 58 MRAT RGFTL+E+M+V+ I+G+LA++ P+ ++ + S + AL+ + Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 Query: 59 SQKGNY 64 +Y Sbjct: 61 LDNHHY 66
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 28.6 bits (64), Expect = 0.022 Identities = 17/91 (18%), Positives = 35/91 (38%), Gaps = 16/91 (17%) Query: 1 MKIGIIGT-GSIGASLARKLAASGHEIKLANSRGPDSIGD----LARDVGASAVSKEEAV 55 MK + G G IG ++++L +GH++ G D++ D + +++ Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQV-----VGIDNLNDYYDVSLKQARLELLAQP--- 52 Query: 56 NGVDVVITSIPFANYPDLANLFSQVPAHVVV 86 I A+ + +LF+ V Sbjct: 53 ---GFQFHKIDLADREGMTDLFASGHFERVF 80
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 426 bits (1096), Expect = e-134 Identities = 228/1053 (21%), Positives = 424/1053 (40%), Gaps = 67/1053 (6%) Query: 8 LSVLAVRERSITLFLICLISLAGVIAFFKLGRAEDPAFTVKVMTVVSVWPGATAQEMQDQ 67 ++ +R L ++ +AG +A +L A+ P ++V + +PGA AQ +QD Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 68 VAEKIEKRLQELRWYDRTETYT-RPGMAFTTLTLLDSTPP----SQVPDEFYQARKKIGD 122 V + IE+ + + + + G TLT T P QV ++ A Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPL--- 117 Query: 123 EAMTLPAGVIGPMVNDEYSDVTFAL---FALKAKGEPQRVLARDAES-LRQRLLHVPGVK 178 LP V ++ E S ++ + F G Q ++ S ++ L + GV Sbjct: 118 ----LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVG 173 Query: 179 KVNIVGEQPE-RIYVEFSHERLATLGISPQEVFAALNNQNALTPAGSVETRGP------Q 231 V + G Q RI+++ + L ++P +V L QN AG + Sbjct: 174 DVQLFGAQYAMRIWLDA--DLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLN 231 Query: 232 VFIRLDGAFDELQKIRDTPVVAQ--GRTLKLADIATVKRGYEDPATFMIRNGGEPALLLG 289 I F ++ + G ++L D+A V+ G E+ NG +PA LG Sbjct: 232 ASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARING-KPAAGLG 290 Query: 290 IVMRDGWNGLDLGKALDHEVGAINAELPLGMSLNKVTDQAVNISSAVDEFMIKFFVALLV 349 I + G N LD KA+ ++ + P GM + D + ++ E + F A+++ Sbjct: 291 IKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIML 350 Query: 350 VMLVCFISMG-WRVGVVVAAAVPLTLAVVFVIMAMSGKNFDRITLGSLILALGLLVDDAI 408 V LV ++ + R ++ AVP+ L F I+A G + + +T+ ++LA+GLLVDDAI Sbjct: 351 VFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAI 410 Query: 409 IAIEMMV-VKMEEGYDRIAASAYAWSHTAAPMLSGTLVTAVGFMPNGFARSTAGEYTSNM 467 + +E + V ME+ A+ + S ++ +V + F+P F + G Sbjct: 411 VVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQF 470 Query: 468 FWIVGIALIASWVVAVFFTPYLGVKLL----PEVKQVEGGHATLYDT---PRYNRFRRVL 520 + A+ S +VA+ TP L LL E + +GG ++T N + + Sbjct: 471 SITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSV 530 Query: 521 ARVIAGKWLVAGSVIGLFVLAVLGMGLVKKQFFPVSDRPEVLVELQMPYGTSIAQTSAAA 580 +++ + V+ + F P D+ L +Q+P G + +T Sbjct: 531 GKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVL 590 Query: 581 AKVESWLAEQAEAGIVTAYIGQGAPRFYMAMGPELPDPSFAKIVV-----RTDSQEQRET 635 +V + + +A + + + G + + + A + + R + E Sbjct: 591 DQVTDYYLKNEKANVESVFTVNG-----FSFSGQAQNAGMAFVSLKPWEERNGDENSAEA 645 Query: 636 LKHRLRQAISE-----GLAGEAQVRVTQLVFGPYSPYPVAYRVTGHD--PDTLRSIAAQV 688 + HR + + + + V + + GHD + Sbjct: 646 VIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMA 705 Query: 689 QQVLSASPMMRTVNTDWGTRTPTLHFTLQQDRMQAIGLSSSQVAQQLQFLLTGLPVTAVR 748 Q ++ + +V + T + Q++ QA+G+S S + Q + L G V Sbjct: 706 AQHPAS---LVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFI 762 Query: 749 EDIRTVQVVARSAGDTRLDPAKIMDFTLTGVDGQRVPLSQIGAVDVRMEEPVMRRRDRTP 808 + R ++ ++ R+ P + + +G+ VP S P + R + P Sbjct: 763 DRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLP 822 Query: 809 TITVRGDIADGLQPPDVSTAITRQLQPIIDTLPSGYRIDQAGSIEESGKAMAAMLPLFPI 868 ++ ++G+ A G D + + LP+G D G + + L I Sbjct: 823 SMEIQGEAAPGTSSGDAMALMEN----LASKLPAGIGYDWTGMSYQERLSGNQAPALVAI 878 Query: 869 MLAVTLIILILQVRSISAMVMVFLTSPLGLIGVVPTLILFQQPFGINALVGLIALSGILM 928 V + L S S V V L PLG++GV+ LF Q + +VGL+ G+ Sbjct: 879 SFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSA 938 Query: 929 RNTLILIGQIHH-NEQAGLDPFQAVVEATVQRARPVILTALAAILAFIPLTHSVFWGT-- 985 +N ++++ E+ G +A + A R RP+++T+LA IL +PL S G+ Sbjct: 939 KNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGA 998 Query: 986 ---LAYTLIGGTFAGTVLTLVFLPAMYSIWFRI 1015 + ++GG + T+L + F+P + + R Sbjct: 999 QNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031 Score = 77.2 bits (190), Expect = 2e-16 Identities = 60/333 (18%), Positives = 129/333 (38%), Gaps = 24/333 (7%) Query: 712 LHFTLQQDRMQAIGLSSSQVAQQLQF----LLTGLPVTAVREDIRTVQVVARSAGDTRLD 767 + L D + L+ V QL+ + G + + + + + Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK-N 242 Query: 768 PAKIMDFTL-TGVDGQRVPLSQIGAVDVRMEE-PVMRRRDRTPTITVRGDIADGLQPPDV 825 P + TL DG V L + V++ E V+ R + P + +A G D Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 826 STAITRQLQPIIDTLPSGYRI----DQAGSIEESGKAMAAMLPLFPIMLAVTLIILILQV 881 + AI +L + P G ++ D ++ S + L IML ++ L L Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTL-FEAIMLVFLVMYLFL-- 359 Query: 882 RSISAMVMVFLTSPLGLIGVVPTLILFQQPFGINA--LVGLIALSGILMRNTLILIGQIH 939 +++ A ++ + P+ L+G IL + IN + G++ G+L+ + ++++ + Sbjct: 360 QNMRATLIPTIAVPVVLLGTF--AILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVE 417 Query: 940 -HNEQAGLDPFQAVVEATVQRARPVILTALAAILAFIPL-----THSVFWGTLAYTLIGG 993 + L P +A ++ Q ++ A+ FIP+ + + + T++ Sbjct: 418 RVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSA 477 Query: 994 TFAGTVLTLVFLPAMYSIWFRIRPDGNERPQGG 1026 ++ L+ PA+ + + + +GG Sbjct: 478 MALSVLVALILTPALCATLLKPVSAEHHENKGG 510
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.7 bits (98), Expect = 4e-06 Identities = 19/112 (16%), Positives = 41/112 (36%), Gaps = 9/112 (8%) Query: 68 VSGKVLERFVDTGQAVKRGQPLMRIDPADLKLAAHAQREAVTAAKAQAKQAADEETRYRS 127 + V E V G++V++G L+++ ++ QA E+TRY+ Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGA-------EADTLKTQSSLLQARLEQTRYQI 155 Query: 128 LRSSGAISASSYDQIKATADSAKAQLSSAQAQAEVALNATRYADLVADADGI 179 L S I + ++K + +S + +L +++ Sbjct: 156 LSRS--IELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQK 205 Score = 29.0 bits (65), Expect = 0.035 Identities = 15/83 (18%), Positives = 29/83 (34%), Gaps = 2/83 (2%) Query: 178 GIVMETLVEPGQVVSAGQAVVRVAHAGPREAVIQLPENLRPLIGSAAQATLFGNKDLSTT 237 IV E +V+ G+ V G ++++ G ++ +L L Q Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSL--LQARLEQTRYQILSRSIEL 162 Query: 238 TRLRQLSDVADRQTRTFEARYVL 260 +L +L + + VL Sbjct: 163 NKLPELKLPDEPYFQNVSEEEVL 185
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.0 bits (145), Expect = 2e-13 Identities = 26/197 (13%), Positives = 58/197 (29%), Gaps = 16/197 (8%) Query: 20 RDQIVIAATEHFSQYGYGKTTVSDLARAIGFSKAYIYKFFESKQAIGEMICANCLSEIEA 79 R I+ A FSQ G T++ ++A+A G ++ IY F+ K + + E+ Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSD----LFSEIWELSES 68 Query: 80 EVRAAVNET-DRPPEKLRRMFKSVVEASIRLFSHDR---------KLYEIATSAATERWQ 129 + E + P + + ++ + + Q Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 130 ATLIYEDNLKAMLQNILQEGRQTGDFERKTPLDETVMAIYLVMRPYINPLLLQ-HTFDHT 188 A ++ L+ + + + + + L +FD Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLK 188 Query: 189 DEGPSQLSSLVLRSLSP 205 E +++L Sbjct: 189 KEA-RDYVAILLEMYLL 204
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 508 bits (1310), Expect = 0.0 Identities = 173/476 (36%), Positives = 251/476 (52%), Gaps = 33/476 (6%) Query: 3 QRQKILIVDDEPDIRELLEITLGRMKLDTRSARNVAEAHDWLAREPFDMCLTDMRLPDGN 62 IL+ DD+ IR +L L R D R N A W+A D+ +TD+ +PD N Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GLELVQHIQHGYPHVPVAMITAHGNLDTAIHALKAGAFDFVTKPVDLNRLRELVNSALSL 122 +L+ I+ P +PV +++A TAI A + GA+D++ KP DL L ++ AL+ Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 123 PSATQPVHSIDSR----LLGDSPPMRTLRNQIGKLARSQAPIYISGESGSGKELVARLIH 178 P DS+ L+G S M+ + + +L ++ + I+GESG+GKELVAR +H Sbjct: 122 PKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALH 181 Query: 179 EQGPRIDKPFVPVNCGAIPSELMESEFFGHRKGSFSGAHEDKPGLFQAAHNGTLFLDEVA 238 + G R + PFV +N AIP +L+ESE FGH KG+F+GA G F+ A GTLFLDE+ Sbjct: 182 DYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIG 241 Query: 239 DLPLAMQVKLLRAIQEKSIRSVGGQQEQVVDVRILCATHKDLNIEVAAGRFRQDLYYRLN 298 D+P+ Q +LLR +Q+ +VGG+ DVRI+ AT+KDL + G FR+DLYYRLN Sbjct: 242 DMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLN 301 Query: 299 VIELRVPSLRERREDIDQLAASVLRRLAGNGAQPVARLHAHALETLKSYRFPGNVRELEN 358 V+ LR+P LR+R EDI L +++ G V R ALE +K++ +PGNVRELEN Sbjct: 302 VVPLRLPPLRDRAEDIPDLVRHFVQQAEKEG-LDVKRFDQEALELMKAHPWPGNVRELEN 360 Query: 359 MLERAYTLCENYEIHASDLRL----------------------------AESASPQAQQG 390 ++ R L I + A G Sbjct: 361 LVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFG 420 Query: 391 ANLADIDNLEDYLESIERTLILQALEETRWNRTAAAERLSLSFRSLRYRLKKLGLD 446 L + L +E LIL AL TR N+ AA+ L L+ +LR ++++LG+ Sbjct: 421 DALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 34.3 bits (78), Expect = 0.006 Identities = 55/299 (18%), Positives = 109/299 (36%), Gaps = 25/299 (8%) Query: 1655 DGLQGVELLEAGNRALQSPLRALQQSGIQALGQRTQAGEVAYGPPSPRKESPLRTAVDAA 1714 D + +E + A + ++ L+ ++ + G + + A Sbjct: 124 DLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEA 183 Query: 1715 ALTTSDIARQ-LEVKVQRMNTAHEREANAISSFQQAYGIASAHLDRLLLRIPELPLPEID 1773 + + LE ++ ++ I + + +A L + Sbjct: 184 EKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMN-FST 242 Query: 1774 DRDVDGGRVRGTFASLQRHHQALDDAI-SAMHQASEKVYTIPGKQATQEQDPALAQLLSV 1832 + A+L+ L+ A+ AM+ ++ I +A + A L Sbjct: 243 ADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEH 302 Query: 1833 EKR-----RRSLGHALETL--AGRGVEAGTATGLELNRVSSQV-----NDLVARRDALLR 1880 + + R+SL L+ A + +EA E N++S DL A R+A + Sbjct: 303 QSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAK-K 361 Query: 1881 QRESGVQEGGLDSEELEMELQLTTSVLQRLRADLLGERQAMEATAKRLDQASR--AALE 1937 Q E+ Q+ LE + +++ + Q LR DL R+A + K L++A+ AALE Sbjct: 362 QLEAEHQK-------LEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALE 413
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 31.1 bits (70), Expect = 0.004 Identities = 20/90 (22%), Positives = 35/90 (38%), Gaps = 2/90 (2%) Query: 2 TSVKDVARLAGVSLMTVSRALNNPEKLSPETYQRVRSAIDELQFVPSLSARRIRGDNLQT 61 TS+ ++A+ AGV+ + + L E ++ S I EL A+ Sbjct: 32 TSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGEL--ELEYQAKFPGDPLSVL 89 Query: 62 RTIGVFALDTATTPFAVELLLSIEQTAQQA 91 R I + L++ T LL+ I + Sbjct: 90 REILIHVLESTVTEERRRLLMEIIFHKCEF 119
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.009 Identities = 12/22 (54%), Positives = 14/22 (63%) Query: 32 VVFVGPSGCGKSTLLRLIAGLD 53 VV G G GKSTL+ + GLD Sbjct: 599 VVLEGTGGIGKSTLINTLVGLD 620
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 38.6 bits (89), Expect = 3e-05 Identities = 76/322 (23%), Positives = 126/322 (39%), Gaps = 34/322 (10%) Query: 104 LRELLPADATQG-YFQAQVDNATVDGRLVTMPWFTDSGLLYYRKDLLDKYQKPVPQTWED 162 L E+ P A Q + D +G+L+ P ++ L Y KDLL P+TWE+ Sbjct: 102 LAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPN----PPKTWEE 157 Query: 163 MTATARHVQQAERGAGNANMWGYVFQGRAYEGLTCNALEWISSQPEGGVINPKGDIVVNS 222 + A + ++ + A N+ F A ++ E G + K D+ V++ Sbjct: 158 IPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKY-----ENGKYDIK-DVGVDN 211 Query: 223 TASKAALTLAKSWVGDISPRGVLNYTEEEGRGVFQSGNALFMRNWPYVWALVQSPDSAVK 282 +KA LT + + +Y+ E F G N P+ W+ + + S V Sbjct: 212 AGAKAGLTFLVDLIKNKHMNADTDYSIAE--AAFNKGETAMTINGPWAWSNIDT--SKVN 267 Query: 283 DKVGIAPLPRGGANGTHASTLGGWGLAVSRYSANPRLAAELVA-YLTS-----AREQKHR 336 V + P +G + L ++ S N LA E + YL + A + Sbjct: 268 YGVTVLPTFKGQPSKPFVGVLSA---GINAASPNKELAKEFLENYLLTDEGLEAVNKDKP 324 Query: 337 ALAGAYNPVIESLYNDPELLATMPYYNQLHGILANGVMRPAAITGSGYPRVSNAFFDRVH 396 A A E L DP + ATM N G + + + +A + V NA Sbjct: 325 LGAVALKSYEEELAKDPRIAATME--NAQKGEIMPNIPQMSAFWYAVRTAVINA------ 376 Query: 397 SVLAGDLPVDQALLELETELTR 418 +G VD+AL + +T +T+ Sbjct: 377 --ASGRQTVDEALKDAQTRITK 396
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 31.3 bits (70), Expect = 0.011 Identities = 20/74 (27%), Positives = 28/74 (37%), Gaps = 7/74 (9%) Query: 24 LAGVLGTSTAVSQAATLEERMAAFEARASAAERRAAAAEQQTQALARELQQIKLANPALQ 83 L + T TA + A E A+ A+R+A +Q A I+ AN Sbjct: 200 LQIRMNTLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAA-------IRAANTYAM 252 Query: 84 PAAPAVAPTVAASP 97 PA +V T A Sbjct: 253 PANGSVVATAAGRG 266
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 54.6 bits (131), Expect = 4e-10 Identities = 20/102 (19%), Positives = 29/102 (28%), Gaps = 1/102 (0%) Query: 576 IEQKSVEPTPTPTPTPTPTPTPTPTPEPTPTPTPTPTP-TPEPVPTPTPTPTPEPAPTPA 634 + +EP P P P P P PEP P P +P P P P P P Sbjct: 55 VAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQP 114 Query: 635 PEPAPAPGIFQTVMLTQNQFNTAGALSVLAQSGEPLRLYNNL 676 + + A + +P+ + Sbjct: 115 KRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASG 156 Score = 51.9 bits (124), Expect = 4e-09 Identities = 24/110 (21%), Positives = 30/110 (27%), Gaps = 1/110 (0%) Query: 577 EQKSVEPTPTPTPTPTPTPTPTPTPEPTP-TPTPTPTPTPEPVPTPTPTPTPEPAPTPAP 635 + P P P P P P P P E P P P P+P P Sbjct: 64 QAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVES 123 Query: 636 EPAPAPGIFQTVMLTQNQFNTAGALSVLAQSGEPLRLYNNLLVLDAEGAR 685 PA T + A + V + + P L N A Sbjct: 124 RPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQA 173 Score = 46.1 bits (109), Expect = 3e-07 Identities = 25/99 (25%), Positives = 32/99 (32%), Gaps = 1/99 (1%) Query: 572 LNLTIEQKSVEPTPTPTPTPTPTPTPTPTPEPTPTPTPTPTPTPEPVPTPTPTPTPEPAP 631 L ++ Q P P + T P P P P PEP P P P P E Sbjct: 33 LYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPV 92 Query: 632 -TPAPEPAPAPGIFQTVMLTQNQFNTAGALSVLAQSGEP 669 P+P P P + Q + + S A E Sbjct: 93 VIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFEN 131 Score = 41.9 bits (98), Expect = 7e-06 Identities = 10/78 (12%), Positives = 17/78 (21%), Gaps = 2/78 (2%) Query: 575 TIEQKSVEPTPTPTPTPTPTPTPTPTPEPTPTPT--PTPTPTPEPVPTPTPTPTPEPAPT 632 + EP P P P + P + +P Sbjct: 74 VEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTA 133 Query: 633 PAPEPAPAPGIFQTVMLT 650 PA + + +T Sbjct: 134 PARPTSSTATAATSKPVT 151 Score = 38.0 bits (88), Expect = 1e-04 Identities = 14/66 (21%), Positives = 21/66 (31%), Gaps = 2/66 (3%) Query: 575 TIEQKSVEPTPTPTPTPTPTPTPTPTPEPTPTPTPTPTPTPEPVPTPTPTPTPEPAPTPA 634 + + +P P P P P + P + P E PT + A T Sbjct: 91 PVVIEKPKPKPKPKP-KPVKKVEQPKRDVKPVESR-PASPFENTAPARPTSSTATAATSK 148 Query: 635 PEPAPA 640 P + A Sbjct: 149 PVTSVA 154
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 32.6 bits (74), Expect = 0.002 Identities = 19/84 (22%), Positives = 37/84 (44%), Gaps = 9/84 (10%) Query: 339 RAGVLFDQSPTSNTDRSPRTPTGDREVFSVGAGYEVTPQLTLDVAYSYLQEESVDVSRAN 398 R G + ++ T + TG VF+ G Y +TP++ + Y + ++ A+ Sbjct: 117 RLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTN----NIGDAH 172 Query: 399 ALGSYSATYQSHANLLGVGATYRF 422 +G + +L +G +YRF Sbjct: 173 TIG-----TRPDNGMLSLGVSYRF 191
>SALVRPPROT#Salmonella virulence-associated 28kDa protein signature. Length = 241 Score = 136 bits (342), Expect = 3e-41 Identities = 76/163 (46%), Positives = 99/163 (60%), Gaps = 6/163 (3%) Query: 74 EVFIHMERSDSRSKGDFAGDKIHLSVAPQHVASAFNAIGKILQADDSPVDKWKVTDMSCA 133 +VFIH R +S+G FAGDK H+SV V AF A+ +L ++DSPVDKWKVTDM Sbjct: 84 DVFIHARRESPQSQGKFAGDKFHISVLRDMVPQAFQALSGLLFSEDSPVDKWKVTDMEKV 143 Query: 134 SSDLQPEKKRVTQGAQFTLYAKPDRADNTYSPEYMGKMRGMISSIERELHTAGVQQSNNR 193 ++ RV+ GAQFTLY KPD+ ++ YS ++ K R I +E L GV S Sbjct: 144 V-----QQARVSLGAQFTLYIKPDQENSQYSASFLHKTRQFIECLESRLSENGV-ISGQC 197 Query: 194 PASDVAPGHWAYASYRNEHRSERAGSSSQANELEKEPFFQLVS 236 P SDV P +W Y SYRNE RS R G Q L +EPF++L++ Sbjct: 198 PESDVHPENWKYLSYRNELRSGRDGGEMQRQALLEEPFYRLMT 240
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.3 bits (180), Expect = 2e-16 Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 7/108 (6%) Query: 5 KISVLLVDDSAVVRQVLVAILN-ETPDIHVMAAASDPIFAMGKLAHEWPDVIVLDVEMPR 63 ++L+ DD A +R VL L+ D+ + + A+ +A D++V DV MP Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAAT---LWRWIAAGDGDLVVTDVVMPD 59 Query: 64 MDGITFLKKIMSERP-TPVVICSSLTQKGAETSLQALSAGAVEIITKP 110 + L +I RP PV++ S+ T+++A GA + + KP Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQN--TFMTAIKASEKGAYDYLPKP 105
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.2 bits (70), Expect = 0.014 Identities = 22/163 (13%), Positives = 63/163 (38%), Gaps = 9/163 (5%) Query: 389 VAAEVRKLAERSQVAAQEIGELSSSSVEMAEKAGKLLDEMVPSINKTSDLVQEISAASEE 448 VA ++ ++ + Q+ E ++ + E+A++A K + N+ + E Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEA-KSNVKANTQTNEVAQSGSETKETQTT 1098 Query: 449 QAAGVAQINTAMTQ--LNQVTQQNASSSEELAA---TAEEMSSQAEQLQQSMSFFTLDSS 503 + A + + TQ+ + +++ +E + QAE +++ + Sbjct: 1099 ETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEP 1158 Query: 504 PKPTTSGSSIDHRSSPSRQPPRTVQPPARKAFAHSMASAPDES 546 T + + P+++ V+ P ++ + ++ E+ Sbjct: 1159 QSQTNTTADT---EQPAKETSSNVEQPVTESTTVNTGNSVVEN 1198
>PF06580#Sensor histidine kinase Length = 349 Score = 36.4 bits (84), Expect = 3e-04 Identities = 20/137 (14%), Positives = 41/137 (29%), Gaps = 51/137 (37%) Query: 413 LMHLLRNSMDHGIESAEARRAAGKPAKGHLNLNAFHDSGSIVIEIADDGAGLNRERILDK 472 + L+ N + HGI P G + L D+G++ +E+ + G+ + Sbjct: 260 VQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTK--- 308 Query: 473 AQQRGLVAAGASLTDQEIYNLIFEPGFSTAEAVTNLSGRGVGMDVVKRNITLLRG---TV 529 G G+ V+ + +L G + Sbjct: 309 ------------------------------------ESTGTGLQNVRERLQMLYGTEAQI 332 Query: 530 DLDSQPGQGTIVRIRLP 546 L + G+ + +P Sbjct: 333 KLSEKQGKVN-AMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 90.3 bits (224), Expect = 1e-24 Identities = 26/117 (22%), Positives = 58/117 (49%), Gaps = 2/117 (1%) Query: 4 SVLVVDDSSSVRQVVGIALKSAGYDVIEACDGKDALGKLSGQKVHLIISDVNMPNMDGIT 63 ++LV DD +++R V+ AL AGYDV + ++ L+++DV MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 FVKEVKKLASYKFTPIIMLTTESQESKKAEGQAAGAKAWVVKPFQPAQMLAAVSKLI 120 + +KK P+++++ ++ + GA ++ KPF +++ + + + Sbjct: 65 LLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.0 bits (65), Expect = 0.033 Identities = 28/205 (13%), Positives = 66/205 (32%), Gaps = 18/205 (8%) Query: 169 QVIDSLKATQASRDQTLSQVRNLTAYTGELRTMAADVAAIAAQTNLLALNA--AIEAARA 226 V+ L A A D +Q L A + R + + L L + Sbjct: 122 DVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSE 181 Query: 227 GEAGRGFAVVADAVRSLSSKSSE---TGQQMSAKVDIINNAITQLVQAASSGADQ----- 278 E R +++ + + ++ + + A+ + I + + + Sbjct: 182 EEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFS 241 Query: 279 ---DSQSVSTSE--QSIQNVLERFQTITRHLAESADLLKQESYGIRDEMTEVLVSLQFQD 333 Q+++ + +E + + ++ + ES + + LV+ F++ Sbjct: 242 SLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQI---ESEILSAKEEYQLVTQLFKN 298 Query: 334 RVSQILSHVRDNIDALHAHLLQASQ 358 + L DNI L L + + Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEE 323
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 35.2 bits (81), Expect = 0.001 Identities = 11/130 (8%), Positives = 41/130 (31%), Gaps = 10/130 (7%) Query: 279 SDYSGARKEELVIQA--EHYRAQQDEMQNDQRSSTQELMRLEREISGIQRWVGELSVLKN 336 +S + ++ + + RA++ + + + + + ++ K+ Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKH 252 Query: 337 RF-----ALVDNAKVLEQQLLAAKDAHDELAGALAQSRQFSAE---DLDERLRDLEKRLK 388 V+ L + E+ A + + + ++ ++LR + Sbjct: 253 AVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIG 312 Query: 389 SVKQQLDHAD 398 + +L + Sbjct: 313 LLTLELAKNE 322
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 28.8 bits (64), Expect = 0.022 Identities = 15/81 (18%), Positives = 22/81 (27%) Query: 29 APSRPELLAPLPPPVEVQSIAPASAPSAHDAPAQAANVVPIARQPERPKIEVPRPSLAST 88 AP++P + + P A P P +P + IE P+P Sbjct: 45 APAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPK 104 Query: 89 RTVAPVEEAAPAPPKAPVVPP 109 E K P Sbjct: 105 PKPVKKVEQPKRDVKPVESRP 125
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 39.9 bits (93), Expect = 8e-07 Identities = 18/80 (22%), Positives = 31/80 (38%) Query: 64 DEAHLLNITVKPENQGRGLGLLLLDHLMKRAYQLNARECFLELRDSNRPAYRLYENYGFN 123 A + +I V + + +G+G LL ++ A + + LE +D N A Y + F Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147 Query: 124 EIGRRRDYYPAPDGGREDAV 143 Y E A+ Sbjct: 148 IGAVDTMLYSNFPTANEIAI 167
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.0 bits (72), Expect = 0.007 Identities = 29/199 (14%), Positives = 64/199 (32%), Gaps = 6/199 (3%) Query: 278 TIEQIYAAATQLSQSVQEMGTIAEVSALNLQLQNTEIEQAAVAVNQMSQAAVEVAGNASN 337 T + A S Q + V+ N ++N E A ++ + N Sbjct: 1165 TADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHR 1224 Query: 338 TVTESEASTQAAAQGQNKLSATISSIKELTENV------LDSSHQAEGLAERTQSISSIL 391 S A + +T++ + N + Q L I Sbjct: 1225 RSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHIS 1284 Query: 392 DVIRAIANQTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTSASTAEIEGLISGVQ 451 + Q N+ N ++ + R F+ + + + +T ++ ++ G+ + V+ Sbjct: 1285 QLEMNNEGQYNVWVSNTSMNKNYSSSQYRRFSSKSTQTQLGWDQTISNNVQLGGVFTYVR 1344 Query: 452 QSTQQTASSLRHTATQANL 470 S ++ ++T Q N Sbjct: 1345 NSNNFDKATSKNTLAQVNF 1363
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 52.2 bits (125), Expect = 2e-09 Identities = 28/155 (18%), Positives = 65/155 (41%), Gaps = 3/155 (1%) Query: 41 LSNIGQSFDMTPAQVGLMLTIYAWVVSLMSLPMMLATRNIERRKLLMFVFGLFVVSHVIS 100 L +I F+ PA + T + S+ + + + ++LL+F + VI Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 101 AMASSFA-ILLVSRVGIAFAHAVFWSVTASLAVRIAPPGKQVQALGLLATGTSLAMVLGI 159 + SF +L+++R A F ++ + R P + +A GL+ + ++ +G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 160 PLGRVLGEALGWRTTFLGIAGVAALVVFLLARALP 194 +G ++ + W ++L + + ++ L Sbjct: 157 AIGGMIAHYIHW--SYLLLIPMITIITVPFLMKLL 189
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 51.5 bits (123), Expect = 4e-11 Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 3/68 (4%) Query: 62 QWLFIELLVVPQQTRGQGMGSRLMQMAEDLAVEKGCVGIWLDTFDFQAP--DFYRRHGYT 119 + IE + V + R +G+G+ L+ A + A E G+ L+T D FY +H + Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147 Query: 120 EFGQIDDY 127 G +D Sbjct: 148 -IGAVDTM 154
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 91.0 bits (226), Expect = 7e-23 Identities = 64/343 (18%), Positives = 121/343 (35%), Gaps = 31/343 (9%) Query: 7 SVIITGITGQDGAYLTQLLLEKGYKVYG--TFRRTSSVNF--WRLEELGVARHPNLHLVE 62 ++TG G G ++++ LLE G++V G V+ RLE L P + Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLA---QPGFQFHK 58 Query: 63 HDLTDLSASIRLVQKAEPTQIYNLAALSFVGVSFDQPITTAEITGLGAVNLLEAIRIVNP 122 DL D L +++ V S + P A+ G +N+LE R Sbjct: 59 IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 123 KIRFYQASTSEMFGKVQEVPQVETTSF-YPRSPYGVAKLYAHWMTINYRESYGIFGASGI 181 + AS+S ++G +++P S +P S Y K M Y YG+ Sbjct: 119 Q-HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLR 177 Query: 182 LFNHESPLRGKEFVTRKITDAAARISLGLPHVLELGNLDARRDWGFAKEYVEGMWRMLQA 241 F P + K T A + G + +RD+ + + E + R+ Sbjct: 178 FFTVYGPWGRPDMALFKFTKA---MLEGKSIDV-YNYGKMKRDFTYIDDIAEAIIRLQDV 233 Query: 242 -EEPDSFVLATNRSETVRDFVSMAF-----KAVDINLEWVGSAENERGIDVSTGKSLVQI 295 D+ + + V++ +++ + E+ GI+ Sbjct: 234 IPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELM-DYIQALEDALGIE---------A 283 Query: 296 NPKF--YRPSEVELLIGNPEKARNVLGWEAKTGLEELCRLMVE 336 +P +V + + V+G+ +T +++ + V Sbjct: 284 KKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVN 326
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 143 bits (363), Expect = 2e-42 Identities = 76/344 (22%), Positives = 129/344 (37%), Gaps = 48/344 (13%) Query: 3 RILITGANGFVGQILCSMLRQAGHHVIA-----------LVGAESALSSHADES-VRCDI 50 + L+TGA GF+G + L +AGH V+ L A L + + D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 51 RDASGLEQALCRAAPTHVVHLAAITHVPTSFNNPVLTWQTNVMGSVNLLQALQRSAPEAF 110 D G+ V V S NP +N+ G +N+L+ + + + Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 111 VLFVSSSEVYGET----FKQGTALGEDSACKPMNPYAASKLAAEA---AFNEYFRQGRKG 163 + + SSS VYG F +DS P++ YAA+K A E ++ + G Sbjct: 122 L-YASSSSVYGLNRKMPFST-----DDSVDHPVSLYAATKKANELMAHTYSHLY--GLPA 173 Query: 164 IVVRPFNHIGARQSPDFATASFARQIALIEAGKQAPQLKVGNLQAARDFLDVHDVCDAYV 223 +R F G PD A F + + GK G + RDF + D+ +A + Sbjct: 174 TGLRFFTVYGPWGRPDMALFKFTKAML---EGKSIDVYNYGKM--KRDFTYIDDIAEAII 228 Query: 224 ALLQLADEQE-------------RYPG-CLNICRGEPTSLQTLLTQLMALSSSVIEVTID 269 L + + P NI P L + L + + Sbjct: 229 RLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNML 288 Query: 270 PDRMRPSDIPSAFGNNSAMRCATGWKPKTKLDDTLEALLNYWRH 313 P ++P D+ + A+ G+ P+T + D ++ +N++R Sbjct: 289 P--LQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRD 330
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 28.6 bits (63), Expect = 0.017 Identities = 17/37 (45%), Positives = 21/37 (56%), Gaps = 2/37 (5%) Query: 94 ALSNLFGGKTSQEERFAAGHWESGVTGAPLLEGAKLA 130 ALSNLFG K E G ++GAP LEG ++A Sbjct: 103 ALSNLFGAKPQTE--LPLGWKGEPLSGAPDLEGMRVA 137
>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature. Length = 428 Score = 26.9 bits (59), Expect = 0.024 Identities = 9/21 (42%), Positives = 13/21 (61%) Query: 56 LETIKSVVETAGGTMDDVTFN 76 L +K V+ T G +DD +FN Sbjct: 59 LLKLKPVLITDEGKIDDKSFN 79
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 73.5 bits (180), Expect = 2e-17 Identities = 48/205 (23%), Positives = 79/205 (38%), Gaps = 28/205 (13%) Query: 1 MTAPLSVAGVDLPQDDQPARVLPARPEALRMKLGETALVVVDMQNAYASLGGYLDLAGFD 60 M P ++ +P A +P + L++ DMQN + +D Sbjct: 1 MAIP-AIQPYQMPT----ASDMPQNKVSWVPDPNRAVLLIHDMQNYF------VDAFTAG 49 Query: 61 VSSTGPVIANIKRACAAARAAGMPVIFFQNGWDPAYVEAGGPGSPNWHKSNALKTMRKRP 120 S + ANI++ G+PV++ PGS N L Sbjct: 50 ASPVTELSANIRKLKNQCVQLGIPVVY-----------TAQPGSQNPDDRALLTDFW--- 95 Query: 121 ELEGQLLAKGGWDYQLVDELKPEPGDIVVPKIRYSGFFNSSFDSMLRSRGIRNLVFTGIA 180 G L G ++ +++ EL PE D+V+ K RYS F ++ M+R G L+ TGI Sbjct: 96 ---GPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITGIY 152 Query: 181 TNVCVESTLRDGFHLEYFGVVLADA 205 ++ T + F + + DA Sbjct: 153 AHIGCLVTACEAFMEDIKAFFVGDA 177
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.0 bits (163), Expect = 8e-16 Identities = 32/167 (19%), Positives = 67/167 (40%), Gaps = 12/167 (7%) Query: 14 KRRMRLMEGKRTLILDAALEIFSRYGVHGSSLDQVASLADVSKTNLLYYFSSKDDLYLNV 73 ++ + + R ILD AL +FS+ GV +SL ++A A V++ + ++F K DL+ + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 74 LRQLLEVWLSPLVHFTAD--KEPVQAIGAYIKAKLEMSRDHPAESRLFCMEVMQGAPLIQ 131 + + A +P+ + + LE + L ME++ Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLL--MEIIFHKCEFV 120 Query: 132 GELQHPLR-------DTVQAKVAVIQHWIDSGQL-APINPHHLIFTL 170 GE+ + ++ ++H I++ L A + + Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIM 167
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 95.0 bits (236), Expect = 3e-25 Identities = 45/161 (27%), Positives = 74/161 (45%), Gaps = 16/161 (9%) Query: 76 GAASAGYGY-YADKQEAALRASMANTGVEVQRQGDQIKLIMPGNITFATDSSAIASSFYS 134 G S G Y + + A + A EVQ + + ++ F + + + + Sbjct: 181 GMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTK----HFTLKSDVLFNFNKATLKPEGQA 236 Query: 135 PLNNLANSLKQFNQNN--IEIIGYTDSTGSRQHNMDLSQQRAQSVATYLTSQGVDQSHLS 192 L+ L + L + + + ++GYTD GS +N LS++RAQSV YL S+G+ +S Sbjct: 237 ALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKIS 296 Query: 193 VRGAGPDQPIASNADANGR---------AQNRRVEVNLKPI 224 RG G P+ N N + A +RRVE+ +K I Sbjct: 297 ARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGI 337
>PF07132#Harpin protein (HrpN) Length = 356 Score = 28.9 bits (64), Expect = 0.031 Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 7/64 (10%) Query: 75 SSIIKDLIDVVTQMAMIVVGSAFVGGAAGAGAGVLFFGVGAVPGGLMGAALGAQASAFIL 134 S+I + L D++T M F+G G G G G+G+ GGL G LG + Sbjct: 45 SNIAEQLSDIMTTMM-------FMGSMMGGGLGGGLGGLGSSLGGLGGGLLGGGLGGGLG 97 Query: 135 GILG 138 LG Sbjct: 98 SSLG 101
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 28.4 bits (63), Expect = 0.048 Identities = 15/55 (27%), Positives = 27/55 (49%), Gaps = 2/55 (3%) Query: 18 ELMLIVGSSVSMLAILAIVASLLARERDDAAQTAARAAANIVQLIDADVLHNAEL 72 E+MLI+ + + A + ++A +R+ D AAQT AR A + + + Sbjct: 10 EMMLIL-LLMGVSAGMVLLAFPASRD-DSAAQTLARFEAQLRFVQQRGLQTGQFF 62
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.0 bits (205), Expect = 1e-20 Identities = 31/126 (24%), Positives = 58/126 (46%), Gaps = 2/126 (1%) Query: 2 RVLIIEDEEKTADYLRRGLTEQGYTVDVARDGIEGLHLALENDHAIVILDVMLPGLDGFG 61 +L+ +D+ L + L+ GY V + + D +V+ DV++P + F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLRALRAR-KQTPVIMLTAREQVDDRIRGLREGADDYLGKPFSFLELVARL-QALTRRSG 119 +L ++ PV++++A+ I+ +GA DYL KPF EL+ + +AL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 120 GHEPLQ 125 L+ Sbjct: 125 RPSKLE 130
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 741 bits (1914), Expect = 0.0 Identities = 281/1033 (27%), Positives = 493/1033 (47%), Gaps = 32/1033 (3%) Query: 12 IDHPVATLLLTFAIVLLGVIAFPRLPIAPLPEAEFPTIQVTAQLPGASPETMASSVATPL 71 I P+ +L +++ G +A +LP+A P P + V+A PGA +T+ +V + Sbjct: 6 IRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVI 65 Query: 72 EVQFSAIPGMTQMTSSSA-LGSTNLTLQFTLNKSIDTAAQEVQAAINTAAGRLPADMPSL 130 E + I + M+S+S GS +TL F D A +VQ + A LP ++ Sbjct: 66 EQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ- 124 Query: 131 PTWRKVNPADSPVLILSVSSS--LMPGTELSDVTETILARQLSQIEGVGQVFITGQQRPA 188 + S +++ S ++SD + + LS++ GVG V + G Q A Sbjct: 125 QGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY-A 183 Query: 189 IRVQAAPEKLAALGLTLADIRLAVQQTSLNLAKGALYGKDSIS------TLSSNDQLFKP 242 +R+ + L LT D+ ++ + +A G L G ++ ++ + + P Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNP 243 Query: 243 QDYAQLIV-SYKNGAPVQLKDVARVVAGSENAYVKAWSGDQQGVNIAIFRQPGANIVETV 301 +++ ++ + +G+ V+LKDVARV G EN V A + + I GAN ++T Sbjct: 244 EEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTA 303 Query: 302 DRIQRELPRLQEMLPATVDVSVLNDRTRTIRASLHEVEMTLLIAVLLVVAVMALFLRQLS 361 I+ +L LQ P + V D T ++ S+HEV TL A++LV VM LFL+ + Sbjct: 304 KAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMR 363 Query: 362 ATLIVSAVLGVSLIASFAMMYLFGFSLNNLTLVAIVVAVGFVVDDAIVVVENIHRHL-EA 420 ATLI + + V L+ +FA++ FG+S+N LT+ +V+A+G +VDDAIVVVEN+ R + E Sbjct: 364 ATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMED 423 Query: 421 GQGMREAAIKGSGEIGFTVVSISFSLLAAFIPLLFMGGVVGRLFKEFALTATATILISVV 480 +EA K +I +V I+ L A FIP+ F GG G ++++F++T + + +SV+ Sbjct: 424 KLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVL 483 Query: 481 VSLTLAPTLAALFMR--APTHNPNQKPGFG------ERLLASYERGLRKALAHQRLMLGV 532 V+L L P L A ++ + H+ N+ FG + + Y + K L L + Sbjct: 484 VALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLI 543 Query: 533 FGLTLVLAVVGYVLIPKGFFPVQDTAFALGTTEAAADISYPDMVEKHLQLAKIVGADPAV 592 + L + VV ++ +P F P +D L + A + + Q+ + Sbjct: 544 YALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKA 603 Query: 593 LAFS--HSVGVSGSNQTIANGRFWISLKPQSERDV---SVSEFIDRLRPKLARVPGIVLY 647 S G S S Q G ++SLKP ER+ S I R + +L ++ + Sbjct: 604 NVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVI 663 Query: 648 LRAGQDINLSSGPSRSQYQYVLKSNDG-ALLNTWTQRLTEKLRSNPA-FRDMSNDLQLGG 705 I + ++ + ++ G L +L +PA + + Sbjct: 664 PFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDT 723 Query: 706 SVTHIDIDRSAAARFGLTTADVDQALYDAFGQRQISEYQTEVNQYKVILELDAQQRGKAE 765 + +++D+ A G++ +D++Q + A G ++++ K+ ++ DA+ R E Sbjct: 724 AQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPE 783 Query: 766 SLAYFYLRSPLTNEMVPLSALAKVGAPRMGPLSISHDGMFPAANLSFNLAPGVALGDAVR 825 + Y+RS EMVP SA G + P+ + APG + GDA+ Sbjct: 784 DVDKLYVRSA-NGEMVPFSAFTTS-HWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMA 841 Query: 826 MLDQAKIEIGMPAAIIGSFQGAAQAFQSSLANQPWLILAALVAVYIILGVLYESFVHPLT 885 +++ + +PA I + G + + S P L+ + V V++ L LYES+ P++ Sbjct: 842 LMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 886 IISTLPSAGIGALLLLWMMGQDFSIMALIGVVLLIGIVKKNGILLVDFALQAQREQGLTP 945 ++ +P +G LL + Q + ++G++ IG+ KN IL+V+FA ++G Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 946 QEAIYEACITRFRPIIMTTLAALLGALPLMLGFGVGAELRQPLGIAVVGGLLVSQMLTLF 1005 EA A R RPI+MT+LA +LG LPL + G G+ + +GI V+GG++ + +L +F Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1006 TTPVIYLQLERLF 1018 PV ++ + R F Sbjct: 1020 FVPVFFVVIRRCF 1032 Score = 99 bits (249), Expect = 2e-23 Identities = 80/526 (15%), Positives = 177/526 (33%), Gaps = 49/526 (9%) Query: 1 MNGRGSVSAWCIDHPVATLLLTFAIVLLGVIAFPRLPIAPLPEAEFPTIQVTAQLP-GAS 59 +N + + LL+ IV V+ F RLP + LPE + QLP GA+ Sbjct: 523 VNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGAT 582 Query: 60 PETMASSVATPLEVQF-SAIPGMTQMTSSSALG----STNLTLQFTLNKSID--TAAQEV 112 E + + + + + + + + N + F K + + Sbjct: 583 QERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENS 642 Query: 113 QAAINTAAGRLPADMPSLPTWRKVNPADSPVLILSVSSSL---------MPGTELSDVTE 163 A+ R ++ + + ++ L ++ + L+ Sbjct: 643 AEAV---IHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARN 699 Query: 164 TILARQLSQIEGVGQVFITGQQ-RPAIRVQAAPEKLAALGLTLADIRLAVQQTSLNLAKG 222 +L + V G + +++ EK ALG++L+DI + Sbjct: 700 QLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTIS--------- 750 Query: 223 ALYGKDSISTLSSNDQLFK------------PQDYAQLIVSYKNGAPVQLKDVARVVAGS 270 G ++ ++ K P+D +L V NG V Sbjct: 751 TALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVY 810 Query: 271 ENAYVKAWSGDQQGVNIAIFRQPGANIVETVDRIQRELPRLQEMLPATVDVSVLNDRTRT 330 + ++ ++G + I PG + + + ++ L LPA + + Sbjct: 811 GSPRLERYNG-LPSMEIQGEAAPGTSSGDAMALME----NLASKLPAGIGYDWT-GMSYQ 864 Query: 331 IRASLHEVEMTLLIAVLLVVAVMALFLRQLSATLIVSAVLGVSLIASFAMMYLFGFSLNN 390 R S ++ + I+ ++V +A S + V V+ + ++ LF + Sbjct: 865 ERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDV 924 Query: 391 LTLVAIVVAVGFVVDDAIVVVENI-HRHLEAGQGMREAAIKGSGEIGFTVVSISFSLLAA 449 +V ++ +G +AI++VE + G+G+ EA + ++ S + + Sbjct: 925 YFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILG 984 Query: 450 FIPLLFMGGVVGRLFKEFALTATATILISVVVSLTLAPTLAALFMR 495 +PL G + ++ + ++++ P + R Sbjct: 985 VLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030 Score = 91.1 bits (226), Expect = 1e-20 Identities = 62/334 (18%), Positives = 127/334 (38%), Gaps = 14/334 (4%) Query: 700 DLQLGGS--VTHIDIDRSAAARFGLTTADVDQALYDAFGQRQISEYQTEVNQYKVILELD 757 D+QL G+ I +D ++ LT DV L Q + L Sbjct: 174 DVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNAS 233 Query: 758 AQQRGKAESLAYF---YLRSPLTNEMVPLSALAKVGAPRMGPLSISHDGMF---PAANLS 811 + + ++ F LR +V L +A+V +G + + PAA L Sbjct: 234 IIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARV---ELGGENYNVIARINGKPAAGLG 290 Query: 812 FNLAPGVALGDAVRMLDQ--AKIEIGMPAAI-IGSFQGAAQAFQSSLANQPWLILAALVA 868 LA G D + + A+++ P + + Q S+ + A++ Sbjct: 291 IKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIML 350 Query: 869 VYIILGVLYESFVHPLTIISTLPSAGIGALLLLWMMGQDFSIMALIGVVLLIGIVKKNGI 928 V++++ + ++ L +P +G +L G + + + G+VL IG++ + I Sbjct: 351 VFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAI 410 Query: 929 LLVDFALQAQREQGLTPQEAIYEACITRFRPIIMTTLAALLGALPLMLGFGVGAELRQPL 988 ++V+ + E L P+EA ++ ++ + +P+ G + + Sbjct: 411 VVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQF 470 Query: 989 GIAVVGGLLVSQMLTLFTTPVIYLQLERLFHRRH 1022 I +V + +S ++ L TP + L + H Sbjct: 471 SITIVSAMALSVLVALILTPALCATLLKPVSAEH 504
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 60.2 bits (146), Expect = 5e-12 Identities = 26/131 (19%), Positives = 58/131 (44%), Gaps = 6/131 (4%) Query: 55 VTGIGSV-LSLQSVVIRPQVDGVLTRVLVREGQQVKAGELLATLDDRSIRASLEQTRAQL 113 T G + S +S I+P + ++ ++V+EG+ V+ G++L L A +T++ L Sbjct: 84 ATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSL 143 Query: 114 AQSKA-----QLDVAQLDLKRYRQLTEDNGISRQTFDQQQALVRQLAATAQGNEASINAA 168 Q++ Q+ ++L + +L + Q +++ L Q + Sbjct: 144 LQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKY 203 Query: 169 QVQLSYTQIRS 179 Q +L+ + R+ Sbjct: 204 QKELNLDKKRA 214 Score = 40.2 bits (94), Expect = 1e-05 Identities = 39/206 (18%), Positives = 75/206 (36%), Gaps = 25/206 (12%) Query: 103 RASLEQTRAQLAQSKAQLDVAQLDLKRYRQLTEDNGISRQTFDQQQALVRQLAATAQGNE 162 L ++QL Q ++++ A+ + + +T+ + D+ + + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEY---QLVTQL--FKNEILDKLRQTTDNIGLL----T 315 Query: 163 ASINAAQVQLSYTQIRSPVTGRVGIRNV-DEGNFMRVSDAEGLFS-VTQIDPIAVEFSLP 220 + + + + IR+PV+ +V V EG V+ AE L V + D + V + Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGV--VTTAETLMVIVPEDDTLEVTALVQ 373 Query: 221 QQMLPTLQGLIAAHSAAAVKAYQGDGATNGLLLGEGTL----SLIDNQVSATTGTIRAKA 276 G I A +K G L+G+ ++ D ++ I + Sbjct: 374 ----NKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIE 429 Query: 277 RF----KNPGEQLWPGQLVTVKIQTG 298 N L G VT +I+TG Sbjct: 430 ENCLSTGNKNIPLSSGMAVTAEIKTG 455 Score = 36.7 bits (85), Expect = 1e-04 Identities = 11/101 (10%), Positives = 34/101 (33%), Gaps = 1/101 (0%) Query: 79 RVLVREGQQVKAGELL-ATLDDRSIRASLEQTRAQLAQSKAQLDVAQLDLKRYRQLTEDN 137 L++E + L+ RA A++ + + V + L + L Sbjct: 188 TSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQ 247 Query: 138 GISRQTFDQQQALVRQLAATAQGNEASINAAQVQLSYTQIR 178 I++ +Q+ + + ++ + + ++ + Sbjct: 248 AIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEE 288
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.4 bits (63), Expect = 0.026 Identities = 12/32 (37%), Positives = 16/32 (50%), Gaps = 1/32 (3%) Query: 152 TIDDRAFAADYGRAGGDGHACLGLSVNWCQSR 183 I+D A A DY R G G A L ++ W + Sbjct: 91 LIEDIAVAKDY-RKKGVGTALLHKAIEWAKEN 121
>cloacin#Cloacin signature. Length = 551 Score = 43.5 bits (102), Expect = 1e-06 Identities = 35/116 (30%), Positives = 42/116 (36%), Gaps = 8/116 (6%) Query: 122 GTPSADSGGGGTPDATGGGGGDTPSATGGGGGDTPTATGGGGSGGGGTPTATGGGSGGTP 181 G P+ GGG D +G + P GGG G GG G G GG G SGG Sbjct: 22 GGPTGLGVGGGASDGSGWSSENNPW--GGGSGSGIHWGGGSGHGNGGG----NGNSGGGS 75 Query: 182 TATGGGEGGVTPQI--TPQLANPNRTSGTGSVSDTAGSTEQAGKINVVKDTIKVGA 235 G P P L+ P S+S A S A + +K K G Sbjct: 76 GTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIADIMAALKGPFKFGL 131
>PF06704#DspF/AvrF protein Length = 129 Score = 225 bits (575), Expect = 7e-80 Identities = 101/129 (78%), Positives = 110/129 (85%) Query: 3 MKTSQPDFARFINSLGAQLGTSLTLQNGVCALYDGQNNEAAIIELPEHSEMVIFHCRIGR 62 M S DF+R I SLGAQLGTSLT QNGVCALYD Q+NEAA+IE+P+HSEMVIFHCR+GR Sbjct: 1 MNNSPTDFSRLIKSLGAQLGTSLTAQNGVCALYDSQDNEAAVIEMPDHSEMVIFHCRVGR 60 Query: 63 CPERAPDLLRLLSLNFDVARLHGCWFAVDQGDVRLCAQRELASLDEPAFCDVTRGFISQA 122 P+RA DL +LLSLNFDVAR+HG WFAVDQGDVRLCAQRELA LDE FCD RGFI QA Sbjct: 61 SPDRAADLQKLLSLNFDVARMHGSWFAVDQGDVRLCAQRELAVLDEAQFCDTARGFIVQA 120 Query: 123 REARAFLQA 131 REARA LQA Sbjct: 121 REARALLQA 129
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 36.9 bits (85), Expect = 3e-04 Identities = 29/116 (25%), Positives = 46/116 (39%), Gaps = 13/116 (11%) Query: 1219 GLQRSYGVNLTTPFIILADKATGLWPTAGATGNRNYILNAERCEG-GVTLYLISEGAGNV 1277 G Q+ + V++ P+ + K T + G TGN + N G G+ +YL + + Sbjct: 61 GNQKDFTVDMNCPYSLGTMKVT--ITSNGQTGNSILVPNTSTASGDGLLIYLYNSNNSGI 118 Query: 1278 SGGFGAGKDYWPGFFDANNPARSVDV-------GNNRTLTPNFRLGVDVTATVAAS 1326 G PG PAR + + GN ++L TAT+ AS Sbjct: 119 GNAVTLGSQVTPGKITGTAPARKITLYAKLGYKGNMQSLQAG---TFSATATLVAS 171
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 32.6 bits (74), Expect = 0.003 Identities = 21/92 (22%), Positives = 33/92 (35%), Gaps = 2/92 (2%) Query: 357 VTPSAIVKRAAERLPAPAPVAERPVRVAERPPLPKPVQSAQLAENLPSPKTAQPLPVAQQ 416 P +V+ E P P P E PV + + P PKP + + + PK ++ Sbjct: 68 PPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKP--KPVKKVEQPKRDVKPVESRP 125 Query: 417 PTAPEALQPAPAAESAPAVEIAQSAPVVEPDP 448 + E PA S ++ V P Sbjct: 126 ASPFENTAPARPTSSTATAATSKPVTSVASGP 157 Score = 32.3 bits (73), Expect = 0.004 Identities = 24/141 (17%), Positives = 42/141 (29%), Gaps = 6/141 (4%) Query: 349 PVTASIPLVTPSAIVKR-AAERLPAPAPVAERPVRVAERPPLPKPVQSAQLAENLPSPKT 407 S+ +V P+ + A + P P E PP PV E Sbjct: 47 AQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVV----IEKPKPKPK 102 Query: 408 AQPLPVAQQPTAPEALQPAPAAESAPAVEIAQSAPVVEPDPLTNRIQLPRIRDDRSSPRK 467 +P PV + ++P + ++P E A + Sbjct: 103 PKPKPVKKVEQPKRDVKPVESRPASPF-ENTAPARPTSSTATAATSKPVTSVASGPRALS 161 Query: 468 RDDDEYRSGPRELPTGPRVVV 488 R+ +Y + + L +V V Sbjct: 162 RNQPQYPARAQALRIEGQVKV 182
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 275 bits (706), Expect = 6e-92 Identities = 111/320 (34%), Positives = 152/320 (47%), Gaps = 45/320 (14%) Query: 32 DMDLLLCGETGTGKDTLANRIHELSSRS-GPFVGMNCAAIPESLAESQLFGVVNGAFTGV 90 D+ L++ GE+GTGK+ +A +H+ R GPFV +N AAIP L ES+LFG GAFTG Sbjct: 160 DLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGA 219 Query: 91 CRAREGYIEASSGGTLYLDEIDSMPLSLQAKLLRVLESRGIERLGSTEFIPVDLRIIASA 150 G E + GGTL+LDEI MP+ Q +LLRVL+ +G I D+RI+A+ Sbjct: 220 QTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAAT 279 Query: 151 QRPLDELVEQGLFRRDLFFRLNVLTLHLPALRKRREQILPLFDQFTQGIAAEFGRPAPAL 210 + L + + QGLFR DL++RLNV+ L LP LR R E I L F Q E G Sbjct: 280 NKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRF 338 Query: 211 DSGRVQLLLSHDWPGNIRELKSAAKRFVL------------------------------- 239 D ++L+ +H WPGN+REL++ +R Sbjct: 339 DQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAAR 398 Query: 240 ------------GFPLLGADPVEALDPATGLRTQMRIIEKMLIQDALKRHRHNFDAVLQE 287 A +AL P+ + +E LI AL R N Sbjct: 399 SGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADL 458 Query: 288 LELPRRTLYHRMKELGVAAP 307 L L R TL +++ELGV+ Sbjct: 459 LGLNRNTLRKKIRELGVSVY 478
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 255 bits (654), Expect = 2e-84 Identities = 104/358 (29%), Positives = 167/358 (46%), Gaps = 57/358 (15%) Query: 1 MSLDERFEDDLDEERVPNLGIVAES------------ISQLGIDVLLSGETGTGKDTIAR 48 ++ +R L+++ + +V S + Q + ++++GE+GTGK+ +AR Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVAR 178 Query: 49 RIHEMSGRKGR-LVAMNCAAIPESLAESELFGVVSGAYTGADRSRVGYVEAAQGGTLYLD 107 +H+ R+ VA+N AAIP L ESELFG GA+TGA G E A+GGTL+LD Sbjct: 179 ALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLD 238 Query: 108 EIDSMPLSLQAKLLRVLETRALERLGSTSTIKLDICVIASAQCSLDDAVERGQFRRDLYF 167 EI MP+ Q +LLRVL+ +G + I+ D+ ++A+ L ++ +G FR DLY+ Sbjct: 239 EIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYY 298 Query: 168 RLNVLTLKLPPLRNQSDRIVPLFTRFTAAAARELGVPVPDVCPLLHKVLLGHDWPGNIRE 227 RLNV+ L+LPPLR++++ I L F A +E G+ V +++ H WPGN+RE Sbjct: 299 RLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVRE 357 Query: 228 LKAAAKR---------------------HVLGFPLLGAEPQGEEHLACG----------- 255 L+ +R + P+ A + Sbjct: 358 LENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFA 417 Query: 256 -----------LKSQLRVIEKALIQESLKRHDNCVDSVSLELDVPRRTLYRRIKELQI 302 L +E LI +L + L + R TL ++I+EL + Sbjct: 418 SFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 31.8 bits (72), Expect = 0.002 Identities = 13/66 (19%), Positives = 30/66 (45%), Gaps = 12/66 (18%) Query: 138 HATPETLLTLLRSAAW---------QARLKPLDER-WSISTPLI--LGELSLTLEQLASL 185 + T E +++ L S W + L ++ ++ ++ +G L L++ + L Sbjct: 219 YITIEPIISKLSSQFWFSSVRRSSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGL 278 Query: 186 RPGDVL 191 R GD++ Sbjct: 279 RVGDII 284
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 30.1 bits (67), Expect = 0.003 Identities = 22/98 (22%), Positives = 39/98 (39%), Gaps = 3/98 (3%) Query: 31 SAERAHRQAQVELKSM---LDHLSETRASLDQERDNHKRRRESLSQDHLQKTISLNDVDR 87 +A + QAQ +L+S+ ++ A+++Q +E+L + + D Sbjct: 159 AATKKLTQAQNKLQSLDPADPGYAQAEAAVEQAGKEATEAKEALDKATDATVKAGTDAKA 218 Query: 88 WHEKEKNMLDRLAFIRQDVQQQQLRVAEQQTLLEHKRL 125 EK N+L + Q Q+ EQ L RL Sbjct: 219 KAEKADNILTKFQGTANAASQNQVSQGEQDNLSNVARL 256
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 163 bits (414), Expect = 6e-50 Identities = 32/212 (15%), Positives = 76/212 (35%), Gaps = 11/212 (5%) Query: 63 ASNNALQSRAVKLGELYQLLMTDQDTGLDNAARVLRKKLMQDDSSSDLKQVLDYTDGDAA 122 A + ++ + + L Q+ + + + + S S LK L+ + + Sbjct: 78 ARVSDVEEQVNQYLSKVPELEQKQNVS-ELLSLLSNS---PNISLSQLKAYLEGKSEEPS 133 Query: 123 KAHVVLQAARKQAEADGEMGEHVVLTQQ-LKQLRRKYGPRARAGIN---SAKAFARPNID 178 + +L R + E+ L +Q L + + G G A ++ ++ Sbjct: 134 EQFKMLCGLRDALKGRPELAHLSHLVEQALVSMAEEQGETIVLGARITPEAYRESQSGVN 193 Query: 179 NKRRVALRNLYSVAVSGQPNITGLIEALLGEQQEAGQFNIDLRDMRTAIADDLSAMTPSA 238 + LR+ Y AV G I + L ++ G + + ++ A++ DL + + Sbjct: 194 PLQ--PLRDTYRDAVMGYQGIYAIWSDLQ-KRFPNGDIDSVILFLQKALSADLQSQQSGS 250 Query: 239 SHEQLRTLMHGLNTARHVTTLLKGCEHLLGRM 270 E+L ++ L + ++ + Sbjct: 251 GREKLGIVISDLQKLKEFGSVSDQVKGFWQFF 282
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 30.7 bits (69), Expect = 0.010 Identities = 16/106 (15%), Positives = 28/106 (26%), Gaps = 13/106 (12%) Query: 263 HAPAEAAAPAQVQAAAPIAPRPVVEAPAR------SPAPTPRPAARTSAAFAPLAKPAAA 316 P P + P P+ E P P P P+P + + Sbjct: 61 EPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKP 120 Query: 317 AGNSEVSALLDTIAGLANEGKSAEARAACE-------RYLQQHEPV 355 + S +T + A + R L +++P Sbjct: 121 VESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQ 166
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 74.5 bits (183), Expect = 5e-16 Identities = 33/117 (28%), Positives = 57/117 (48%), Gaps = 3/117 (2%) Query: 668 TRKRVLVVDDSLTVRELERKLLVGRGYDVSVAVDGMDGWNALRAEDFDLLITDIDMPRMD 727 T +LV DD +R + + L GYDV + + W + A D DL++TD+ MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 728 GIELVTLLRRDTRLQSLPVMVVSYKDREEDRRRGLDAGADYYLAKASFHDDALLDAV 784 +L+ +++ LPV+V+S ++ + + GA YL K F L+ + Sbjct: 62 AFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPK-PFDLTELIGII 115
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 48.7 bits (116), Expect = 2e-08 Identities = 34/184 (18%), Positives = 66/184 (35%), Gaps = 22/184 (11%) Query: 2 KIAIVNDMPMAIEALRRALAFEPAHQVIWVAANGADAVQRSIEQTPDLILMDLIMPVMDG 61 I + +D L +AL+ + V + +N A + DL++ D++MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRA-GYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 62 VEATRRIMAETPCAIVIVTVDREQNMRRVFEAMGHGALDVVDTPAIGGPNPREAAAPLLR 121 + RI P V+V + M + +A GA D + P + E Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAI-KASEKGAYDYLPKP----FDLTELIG---- 113 Query: 122 KILNIDWLMGQRVGRERVVTTSRSEVSRRDRLVAIGSSAGGPAALEILLKGLPENFPAAI 181 + R E S+ E +D + +G SA +L + + + Sbjct: 114 --------IIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLT--- 162 Query: 182 VLVQ 185 +++ Sbjct: 163 LMIT 166
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.2 bits (151), Expect = 7e-13 Identities = 27/114 (23%), Positives = 48/114 (42%), Gaps = 3/114 (2%) Query: 19 VLLVDDQAMIGEAVRRGLAGHESIDFHFCADPHQAIAQAVQIKPTVILQDLVMPGLDGLT 78 +L+ DD A I + + L+ D ++ +++ D+VMP + Sbjct: 6 ILVADDDAAIRTVLNQALSR-AGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 79 LVREYRSNPLTRDIPIIVLSTKEDPLIKSAAFAAGANDYLVKLPDNIELVARIR 132 L+ + D+P++V+S + + A GA DYL K D EL+ I Sbjct: 65 LLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 30.5 bits (69), Expect = 0.009 Identities = 16/48 (33%), Positives = 29/48 (60%), Gaps = 3/48 (6%) Query: 2 SSGLVDAKDLLLMSAEEE-DQAAVDDVAAEVERLRASLEKL--EFRRM 46 SSG+ AK + + + ++ ++ DV+ E+E+L A+LEK E R + Sbjct: 11 SSGVAIAKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAI 58
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 52.7 bits (126), Expect = 1e-10 Identities = 25/132 (18%), Positives = 48/132 (36%), Gaps = 11/132 (8%) Query: 28 REGSEQRRQVILDAAMRIVVRDGVRAVRHRAVAAEAGVPLSATTYYFKDIDDLLTDAFAQ 87 ++ +++ RQ ILD A+R+ + GV + +A AGV A ++FKD DL ++ + Sbjct: 6 KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65 Query: 88 YVQRSADYLARLWQTTEIILREMMSRSSGSPTDRFRLADDIARMAMEHIRHQLLTRREYL 147 + E ++ G P R + + L Sbjct: 66 SESNIGEL-----------ELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIF 114 Query: 148 IAEQAFYHEALI 159 + A++ Sbjct: 115 HKCEFVGEMAVV 126
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 116 bits (292), Expect = 6e-33 Identities = 46/128 (35%), Positives = 67/128 (52%), Gaps = 11/128 (8%) Query: 130 AKQTERGTLVTFGDVLFDYNKAELKPTAQGDIGKLAAFLQEN--TDRKVIVEGYTDSTGS 187 A + + DVLF++NKA LKP Q + +L + L D V+V GYTD GS Sbjct: 207 APEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGS 266 Query: 188 ASYNQSLSERRANSVRMALVRMGVDPARVVTMGYGKEYPVADNSSNSGR---------AM 238 +YNQ LSERRA SV L+ G+ ++ G G+ PV N+ ++ + A Sbjct: 267 DAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAP 326 Query: 239 NRRVEVTI 246 +RRVE+ + Sbjct: 327 DRRVEIEV 334
>adhesinb#Adhesin B signature. Length = 310 Score = 26.7 bits (59), Expect = 0.030 Identities = 7/36 (19%), Positives = 15/36 (41%) Query: 18 LRGLKLAALAIGSTFILAGCAGNPPSEQYAVSQSAV 53 ++ + L + + LA C+ S + S+ V Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSSKLNV 36
>PF06917#Periplasmic pectate lyase Length = 555 Score = 28.0 bits (62), Expect = 0.026 Identities = 15/37 (40%), Positives = 22/37 (59%), Gaps = 2/37 (5%) Query: 150 PEFADIAQDANLM--DDMIVQIPEALTALYLLCQAPD 184 PEF +IA++AN++ D + I L L +L Q PD Sbjct: 297 PEFGEIAREANVLFRDMRPLLIDNPLAMLDILRQQPD 333
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 267 bits (683), Expect = 4e-88 Identities = 125/403 (31%), Positives = 211/403 (52%), Gaps = 17/403 (4%) Query: 9 LLVLNTGSSSIKFSLYSAAALAASGPQCLGNGSFEVRKDTERLIFQGADGCAQTREEWSR 68 +LV+N GSSS+K+ L + L G E + L+ A+G ++ + Sbjct: 3 ILVINCGSSSLKYQLIESKD-----GNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMK 57 Query: 69 NGASLNKASVNSGTLANLMGWIERHADGQICAAAHRVVHGGSRTQVAARVDAVLMADMQA 128 + K +++ ++ G I+ ++ I A HRVVHGG + + ++ + Sbjct: 58 DHKDAIKLVLDALVNSDY-GVIKDMSE--IDAVGHRVVHGGEYFTSSVLITDDVLKAITD 114 Query: 129 LVPLAPLHQPLCLAPMTYLSREHGGLVQFACFDTAFHHTLDALETRFGLPAALTAQ-GLR 187 + LAPLH P + + ++ + A FDTAFH T+ + +P + +R Sbjct: 115 CIELAPLHNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIR 174 Query: 188 RYGFHGLSYEYIASVLPHY-DQRAAQGRTIVAHLGNGASLCAMHNRVSRGTTMGFSTLDG 246 +YGFHG S++Y++ ++ + I HLGNG+S+ A+ N S T+MGF+ L+G Sbjct: 175 KYGFHGTSHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEG 234 Query: 247 VLMGTRPGRLDPGVLLYLLRERRMSVQALEHLLYHECGLLGVSGGISSDMRELSASQA-- 304 + MGTR G +DP ++ YL+ + +S + + ++L + G+ G+S GISSD R+L + Sbjct: 235 LAMGTRSGSIDPSIISYLMEKENISAEEVVNILNKKSGVYGIS-GISSDFRDLEDAAFKN 293 Query: 305 --PEARDAIALFVRSVVREIGSLAAILGGVDALVFTGGIGEHAADVRDAILDGCAWLGLK 362 A+ A+ +F V + IGS AA +GGVD +VFT GIGE+ ++R+ ILDG +LG K Sbjct: 294 GDKRAQLALNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFK 353 Query: 363 RD--RAVATQPGARLSHPDSAVSAWTIATDENAIIARHALGLL 403 D + A +S DS V+ + T+E +IA+ ++ Sbjct: 354 LDKEKNKVRGEEAIISTADSKVNVMVVPTNEEYMIAKDTEKIV 396
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 78.7 bits (194), Expect = 5e-19 Identities = 31/146 (21%), Positives = 62/146 (42%), Gaps = 1/146 (0%) Query: 9 HVLIVEDDLRLAELTSDYLQNNGLSVSIEGNGALAAARIIDEQPDLVILDLMLPGEDGFS 68 +L+ +DD + + + L G V I N A I DLV+ D+++P E+ F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 69 ICRTVRDRYDG-PILMLTARTDDTDHIQGLDTGADDFVCKPVHPRVLLARIHALLRRSEA 127 + ++ P+L+++A+ I+ + GA D++ KP L+ I L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 128 PQVPAAELRRLVFGPLVVDNALREAW 153 + + + A++E + Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEIY 150
>PF06580#Sensor histidine kinase Length = 349 Score = 31.8 bits (72), Expect = 0.005 Identities = 18/107 (16%), Positives = 32/107 (29%), Gaps = 25/107 (23%) Query: 359 LQNLVSNAMRHA------ETEVRISYQLGAQQCRINVDDDGPGVPEEAWEQIFTPFMRID 412 +Q LV N ++H ++ + + V++ G + E Sbjct: 260 VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE---------- 309 Query: 413 DSRTRTSGGHGLGLSIVR-RIIHWHEGRALVGRSVGLGGACFSLSWP 458 G GL VR R+ + A + S G + P Sbjct: 310 --------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 76.2 bits (187), Expect = 1e-18 Identities = 64/229 (27%), Positives = 96/229 (41%), Gaps = 30/229 (13%) Query: 34 DDPRP--VVVLPELLQPARLDQLLLS----VYGPQ-LMASQLPVLVSQWAKFYFMQIIPP 86 D+P P + L + P L LL +Y Q +M + L+S WA++Y ++PP Sbjct: 47 DEPAPLNAMTLAQWSSPNVLSSLLAVYSDHIYRNQPMMIRENKPLISLWAQWYIGLMVPP 106 Query: 87 VLVASLVQGWHWPLTLDQVGVALDERGVPCGVRSLGQGEVWRDV-------PVDPFQRFT 139 +++A L Q ++ + E G W DV P P R Sbjct: 107 LMLALLTQEKALDVSPEHFHAEFHETGRV--------ACFWVDVCEDKNATPHSPQHRME 158 Query: 140 GLLDDNLQPFITALSAYGELPGAVLWSSAGDYLEGCLTRLAECSDAPLAAGM--ALLTEK 197 L+ L P + AL A GE+ G ++WS+ G + LT + + + AL EK Sbjct: 159 TLISQALVPVVQALEATGEINGKLIWSNTGYLINWYLTEMKQLLGEATVESLRHALFFEK 218 Query: 198 RRPDGRSNPLFQAVRYVVQAQGAEPRRQRRVCCLSHRVEWVGRCEHCPL 246 +G NPL+ R VV G RR CC +R+ V +C C L Sbjct: 219 TLTNGEDNPLW---RTVVLRDGL---LVRRTCCQRYRLPDVQQCGDCTL 261
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 101 bits (252), Expect = 1e-28 Identities = 54/187 (28%), Positives = 97/187 (51%), Gaps = 11/187 (5%) Query: 26 ASIQRSVAKRQAEFLAGRLCAREALSQLDGRLHTPTLGEDRAPIWPSDVCGSITHSTGWA 85 ++ + KR+AE LAGR+ A AL ++ G P +G+ R P+WP + GSI+H A Sbjct: 37 DRLRSAGRKRKAEHLAGRIAAVHALREV-GVRTVPGMGDKRQPLWPDGLFGSISHCATTA 95 Query: 86 AAVVAHKQQWRGLGLDTENLLSHDRASRLAGEILTAAELADM-AAGPQDQLALRVTLTFS 144 AV++ + +G+D E ++S A+ LA I+ + E + A+ LAL L FS Sbjct: 96 LAVISR----QRIGIDIEKIMSQHTATELAPSIIDSDERQILQASLLPFPLALT--LAFS 149 Query: 145 IKEALFKALYPIVQKRFYFEDAQLLEWSADGNARLRLLIDLSSEWHAGKELDGQFNVLGD 204 KE+++KA + F A++ +A + L LL ++ A + + ++ + Sbjct: 150 AKESVYKA-FSDRVTLPGFNSAKVTSLTA-THISLHLLPAFAAT-MAERTVRTEWFQRDN 206 Query: 205 HLLSLVA 211 +++LV+ Sbjct: 207 SVITLVS 213
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.1 bits (208), Expect = 6e-21 Identities = 33/120 (27%), Positives = 58/120 (48%), Gaps = 1/120 (0%) Query: 2 KLLVVEDEALLRHHLRTRLTEAGHVVEAVANAEEALYQVAQFNHDLAVIDLGLPGIGGLD 61 +LV +D+A +R L L+ AG+ V +NA +A + DL V D+ +P D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LIRQLRALGKAFPILILTARGNWQDKVEGLAAGADDYVVKPFQFEE-LEARLNALLRRSS 120 L+ +++ P+L+++A+ + ++ GA DY+ KPF E + AL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 102 bits (256), Expect = 2e-28 Identities = 67/251 (26%), Positives = 108/251 (43%), Gaps = 23/251 (9%) Query: 11 LKGRVILVTGAARGIGAAAARAYAAHGASVVLLGRTEASLAEVSDQIKSAGQPQPLIIAL 70 ++G++ +TGAA+GIG A AR A+ GA + + L +V +K+ + A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE---AF 62 Query: 71 NLENATAQQYRELAARVEHEFGRLDGLLHNASIIGPRTPLEQLPDEDFMQVMHVNVNATF 130 + + E+ AR+E E G +D L++ A ++ P + L DE++ VN F Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRP-GLIHSLSDEEWEATFSVNSTGVF 121 Query: 131 MLTRALLPLLKRSEDASIAFTSSSVGRKGRANWGAYGVSKFATEGLMQTLADELEGVTAV 190 +R++ + SI S+ R + AY SK A + L EL + Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAE-YNI 180 Query: 191 RANSINPGATRTGMRAQAYPDEN-----------------PLNNPA-PEDIMPVYLYLMG 232 R N ++PG+T T M+ + DEN PL A P DI L+L+ Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 233 PDSTGINGQAL 243 + I L Sbjct: 241 GQAGHITMHNL 251
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 115 bits (291), Expect = 9e-38 Identities = 34/89 (38%), Positives = 52/89 (58%), Gaps = 1/89 (1%) Query: 2 TKSELIERIVTHQGLLSSKDVELAIKTMLEQMSQCLATGDRIEIRGFGSFSLHYRAPRVG 61 K +LI + V L+ KD A+ + +S LA G+++++ GFG+F + RA R G Sbjct: 3 NKQDLIAK-VAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKG 61 Query: 62 RNPKTGQSVSLDGKFVPHFKPGKELRDRV 90 RNP+TG+ + + VP FK GK L+D V Sbjct: 62 RNPQTGEEIKIKASKVPAFKAGKALKDAV 90
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 85.2 bits (211), Expect = 6e-21 Identities = 63/338 (18%), Positives = 121/338 (35%), Gaps = 34/338 (10%) Query: 8 VAITGATGFVGSAVVRRLIERTRCAVRVAVRGAY-----------TCASPRISAVAMQSL 56 +TGA GF+G V +RL+E V + Y A P + Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLA 62 Query: 57 APDNRWESF-VAGAQVVIHCAARVHVLNETATEPDHAYFSANVTATLNLAEQAAAAGVKR 115 + + F + V R+ V + E HAY +N+T LN+ E ++ Sbjct: 63 DREGMTDLFASGHFERVFISPHRLAV--RYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 116 FIFISSIKASGESTPPGAPFRADDPCN-PLDPYGVSKQKAEEGLRALAARSGMQVVIIRP 174 ++ SS G + PF DD + P+ Y +K+ E + G+ +R Sbjct: 121 LLYASSSSVYGLNRKM--PFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRF 178 Query: 175 VLVYGPGVKAN--FRSMMRWLDKGLPLPL-GAIDNRRSLVAVGNLADLVVVCVDHPAAAG 231 VYGP + + + + +G + + +R + ++A+ ++ D A Sbjct: 179 FTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHAD 238 Query: 232 QTFLVSDGDDLSTTRLLREMGRALGKPARLLPVPAVLLKGAAALLGKKAFSQRLCSSLQ- 290 + V G ++ R P L+ L LG +A ++ LQ Sbjct: 239 TQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALED----ALGIEA--KKNMLPLQP 292 Query: 291 -------VDISKTCTMLDWHPPVSIEHAMQDTARYYLE 321 D ++ + P +++ +++ +Y + Sbjct: 293 GDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRD 330
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 69.4 bits (170), Expect = 7e-15 Identities = 58/323 (17%), Positives = 112/323 (34%), Gaps = 68/323 (21%) Query: 299 TVLVTGAGGSIGSELCRQILLLQPVQLLLLDHSEFNLYSILSELEQRSARESLSVKLLPI 358 LVTGA G IG + ++ LL Q++ +D N Y +S + R E L+ Sbjct: 2 KYLVTGAAGFIGFHVSKR-LLEAGHQVVGID--NLNDYYDVSLKQAR--LELLAQPGFQF 56 Query: 359 L-GSVRNHPKLLSIMKTWKVDTVYHAAAYKHVPMVEHNIAEGVINNVVGTLNTAQAALQA 417 + + + + + + V+ + V N +N+ G LN + Sbjct: 57 HKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN 116 Query: 418 GVSNFVLIST---------------DKAVRPTNVMGSTKRLAELILQALSRETAPVIFGD 462 + + + S+ D P ++ +TK+ EL+ S ++G Sbjct: 117 KIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSH-----LYG- 170 Query: 463 KANVYQVNKTRFTMVRFGNVLGSSGS---VIPLFHKQIQSGGPLTV-THPKITRYFMTIP 518 T +RF V G G + F K + G + V + K+ R F I Sbjct: 171 ---------LPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYID 221 Query: 519 EAAQLVIQA----------GSMGHGGD--------VFVLDMGEPVKIVELAEKMIHLSGL 560 + A+ +I+ ++ G V+ + PV++++ + + Sbjct: 222 DIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQAL------ 275 Query: 561 AIRSEKNPHGDISIEFTGLRPGE 583 E + L+PG+ Sbjct: 276 ----EDALGIEAKKNMLPLQPGD 294
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.8 bits (121), Expect = 3e-10 Identities = 40/180 (22%), Positives = 65/180 (36%), Gaps = 16/180 (8%) Query: 6 DHKAQTHQRIVKEASMRFRRDGIGATGLQPLMKALGLTHGGFYAHFKSKDDLVEQALSHA 65 +T Q I+ A F + G+ +T L + KA G+T G Y HFK K DL + + Sbjct: 7 QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66 Query: 66 LDNVKGITSEVFARQ--DSLSEFIDLYLSTTSRDAQDGGCPLPTMCL------------- 110 N+ + E A+ D LS ++ + + L + Sbjct: 67 ESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVV 126 Query: 111 ELGQRDQPSETTDKIVLHLLELFENSLAGTGLEPRSV-PILSALVGGLVLARSAADDKLS 169 + QR+ E+ D+I L E + L R I+ + GL+ A Sbjct: 127 QQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFD 186
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 34.2 bits (78), Expect = 2e-04 Identities = 26/125 (20%), Positives = 54/125 (43%), Gaps = 10/125 (8%) Query: 5 LVVVDLQNEYLPTGKLPLSGIEAAAANASRVISHARDTGIPVFHIRH--ESDNEGAAIFT 62 L++ D+QN ++ S + +AN ++ + GIPV + + + A+ T Sbjct: 33 LLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDDRALLT 92 Query: 63 --------KGSDGTQIQPAVAPVGQEPVITKNHINAFRDTDLKTQLDTFDIEDIVVIGAM 114 G +I +AP + V+TK +AF+ T+L + + +++ G Sbjct: 93 DFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITGIY 152 Query: 115 SHMCI 119 +H+ Sbjct: 153 AHIGC 157
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 98.6 bits (245), Expect = 9e-27 Identities = 53/188 (28%), Positives = 81/188 (43%), Gaps = 10/188 (5%) Query: 7 KTAIVTGASSGIGRATAEALVRAGYTVFGTTRKVGDSSTQVSMLTC----------DVTN 56 K A +TGA+ GIG A A L G + VS L DV + Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 57 DESVATLVSTVLARTGRIDLLVNNAGIGLVGGAEEFSIPQVQALFDVNLFGVIRMTNAVL 116 ++ + + + G ID+LVN AG+ G S + +A F VN GV + +V Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 117 PSMRQRGEGRIINIGSILGLIPAPYSSHYSAVKHAVEGYSESLDHEVRAFNIRVSVVEPG 176 M R G I+ +GS +P + Y++ K A +++ L E+ +NIR ++V PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 177 FVRTVFDQ 184 T Sbjct: 189 STETDMQW 196
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 77.8 bits (191), Expect = 4e-19 Identities = 49/185 (26%), Positives = 84/185 (45%), Gaps = 2/185 (1%) Query: 7 VLITGASSGIGAVYAERFARRGHNLVLAARDKPRLDALAARLIKEHDIAVDVLQADLTNA 66 ITGA+ GIG A A +G + + A P +K + AD+ ++ Sbjct: 11 AFITGAAQGIGEAVARTLASQGAH-IAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 67 ADLTALETRL-RDDAQIGILINNAGMAQSGGFLEQSTEAIERLIALNVVALTRLAAAVAP 125 A + + R+ R+ I IL+N AG+ + G S E E ++N + + +V+ Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 126 RFAESGTGSIVNLGSVVGFAPEFGMTVYGATKAFVLYLSQGMHLELAPKGVYIQAVLPAA 185 + +GSIV +GS P M Y ++KA + ++ + LELA + V P + Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 186 TRTEI 190 T T++ Sbjct: 190 TETDM 194
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 44.2 bits (104), Expect = 8e-08 Identities = 16/66 (24%), Positives = 26/66 (39%) Query: 21 QAAWDIVGEAGVRSVSLRECARRANVSHAAPAHHFGSLENLLAEVVADGYERMVDAVQAA 80 A + + GV S SL E A+ A V+ A HF +L +E+ + + Sbjct: 18 DVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEY 77 Query: 81 QRELDD 86 Q + Sbjct: 78 QAKFPG 83
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.8 bits (69), Expect = 0.005 Identities = 17/71 (23%), Positives = 34/71 (47%), Gaps = 3/71 (4%) Query: 139 VPQLTQQVAELTEQLAGIDNTWK---TRVQGMQETLDARKKLVDELEARTKVLNDQLADS 195 + L + A L + A +++ + Q ++ LDA ++ +LEA + L +Q S Sbjct: 283 IKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKIS 342 Query: 196 QAELRSTQARL 206 +A +S + L Sbjct: 343 EASRQSLRRDL 353 Score = 30.0 bits (67), Expect = 0.009 Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 1/58 (1%) Query: 141 QLTQQVAELTEQLAGIDNTWKTRVQGMQETLDARKKLVDELEARTKVLNDQLADSQAE 198 Q+ + + E +LA ++ K + + T + +L +LEA K L ++LA QAE Sbjct: 397 QVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAK-QAE 453
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 52.5 bits (126), Expect = 2e-09 Identities = 27/135 (20%), Positives = 51/135 (37%), Gaps = 7/135 (5%) Query: 10 LIVDDFSDFRSSVRSMLRELGVKEVDTADSGEQALRMCSQKRYDFVLHDFNLGDGRKNGQ 69 L+ DD + R+ + L G +V + R + D V+ D + D N Sbjct: 7 LVADDDAAIRTVLNQALSRAGY-DVRITSNAATLWRWIAAGDGDLVVTDVVMPDE--NAF 63 Query: 70 QVLEDLMIERLLSYESVFIMVTAENSQAMVMSALEWEPDGYLTKPFNRAGLAQRLEK-LV 128 +L + R + ++++A+N+ + A E YL KPF+ L + + L Sbjct: 64 DLLPRIKKARP---DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 129 QRKTLLKPILQALDR 143 + K + Sbjct: 121 EPKRRPSKLEDDSQD 135
>PF06580#Sensor histidine kinase Length = 349 Score = 29.8 bits (67), Expect = 0.009 Identities = 18/101 (17%), Positives = 37/101 (36%), Gaps = 22/101 (21%) Query: 134 IIVNAI--GFARE----QLVISVGDEDGQLKITINDDGPGYPAYLIDQQTDYVQGINQGS 187 ++ N I G A+ ++++ ++G + + + + G + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSL--------------ALKNTK 308 Query: 188 GSTGLGLYFAAHIARLHARGGMQGRIEIANGGVLGGAMFSI 228 STG GL RL G + +I+++ AM I Sbjct: 309 ESTGTGLQNVRE--RLQMLYGTEAQIKLSEKQGKVNAMVLI 347
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 124 bits (311), Expect = 1e-36 Identities = 80/245 (32%), Positives = 121/245 (49%), Gaps = 9/245 (3%) Query: 1 MVTGASSGIGSQVAIWLSQQGARVVLVARNQERLEATRQQLHGEGHGVE--PFDLLENSV 58 +TGA+ GIG VA L+ QGA + V N E+LE L E E P D+ +++ Sbjct: 12 FITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSAA 71 Query: 59 VGGWMKNLAKTYAPFDGLVHAAGVQMPLPIRALGIDQWETVFATNVTSGFSLIKSFRQKG 118 + + + P D LV+ AGV P I +L ++WE F+ N T F+ +S + Sbjct: 72 IDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKYM 131 Query: 119 VFTQGASIVLLSSVMAQVAQPSLMAYCASKGAVESMVRAAALELARDGIRVNAIAPGVVK 178 + + SIV + S A V + S+ AY +SK A + LELA IR N ++PG + Sbjct: 132 MDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGSTE 191 Query: 179 TEMTRKL------EDTVGVDAMSAVEQRHPLG-FGEPLDIAYAVNYLLSPAARWVTGTSM 231 T+M L + V ++ + PL +P DIA AV +L+S A +T ++ Sbjct: 192 TDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMHNL 251 Query: 232 VVDGG 236 VDGG Sbjct: 252 CVDGG 256
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 104 bits (260), Expect = 9e-27 Identities = 88/364 (24%), Positives = 148/364 (40%), Gaps = 17/364 (4%) Query: 21 RNLWVCVFGVFTTIVAMTLLLPFLPLYVEQLGVDNHAAVVLWSGATYGATFLSAAITAPL 80 R L V + V V + L++P LP + L N G L AP+ Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHY--GILLALYALMQFACAPV 62 Query: 81 WGRLGDRYGRKLMLIRASLGMAVAMSLIGLAQTVWQLLLLRLLAGLLGGYASGATILVAT 140 G L DR+GR+ +L+ + G AV +++ A +W L + R++AG+ G + A +A Sbjct: 63 LGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD 122 Query: 141 QTPKARSGWALGVLSSGIMAGSLAGPLMGGVLPPLIGIRNTFFLAGGVIFITFLATLLLL 200 T G +S+ G +AGP++GG++ FF A + + FL LL Sbjct: 123 ITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLL 181 Query: 201 REMPRKAPSRATDSALPAVVKLSGEQRRMITCMFVVAS-LVMFSTMSVEPIITVYLRQLK 259 E + L R M VVA+ + +F M + + L + Sbjct: 182 PE-----SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIF 236 Query: 260 TDNV----TMMAGVVMSA-TALGSILAASRLGRLADRIGYLPVLTSCLAMTALTLIPQAW 314 ++ G+ ++A L S+ A G +A R+G L + I A+ Sbjct: 237 GEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAF 296 Query: 315 VSNVWQLAALRFFMGLALGGL-LPCVAAIIRHTVPNEVAGRMLGYSTSSQYLGQVLGPLA 373 + W A + LA GG+ +P + A++ V E G++ G + L ++GPL Sbjct: 297 ATRGW--MAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLL 354 Query: 374 GGLL 377 + Sbjct: 355 FTAI 358 Score = 57.5 bits (139), Expect = 3e-11 Identities = 41/135 (30%), Positives = 62/135 (45%), Gaps = 2/135 (1%) Query: 247 VEPIITVYLRQL-KTDNVTMMAGVVMSATALGSILAASRLGRLADRIGYLPVLTSCLAMT 305 + P++ LR L +++VT G++++ AL A LG L+DR G PVL LA Sbjct: 24 IMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGA 83 Query: 306 ALTLIPQAWVSNVWQLAALRFFMGLALGGLLPCVAAIIRHTVPNEVAGRMLGYSTSSQYL 365 A+ A +W L R G+ G A I + R G+ ++ Sbjct: 84 AVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGF 142 Query: 366 GQVLGPLAGGLLGGY 380 G V GP+ GGL+GG+ Sbjct: 143 GMVAGPVLGGLMGGF 157
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 505 bits (1302), Expect = e-179 Identities = 182/494 (36%), Positives = 256/494 (51%), Gaps = 22/494 (4%) Query: 5 IKILLIDDDSQRRRDLAVILNFLGEENLSCSSQDWQQVVGSLASTREVLC-----VLVGN 59 IL+ DDD+ R L L+ G + + A+ + ++V + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRI---------TSNAATLWRWIAAGDGDLVVTD 54 Query: 60 VSAPG-SLQGLLKTIAAWDEFLPVLLLSENSSVELP-EDLRRRVLSALEMPPSYSKLLDS 117 V P + LL I LPVL++S ++ + + L P ++L+ Sbjct: 55 VVMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGI 114 Query: 118 LHRAQVYREMYDQARERGRHREPNLFRSLVGTSRAIQHVRQMMQQVADTDASVLILGESG 177 + RA + R + LVG S A+Q + +++ ++ TD +++I GESG Sbjct: 115 IGRALAEP----KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESG 170 Query: 178 TGKEVVARNLHYHSKRRDAPFVPVNCGAIPAELLESELFGHEKGAFTGAITSRAGRFELA 237 TGKE+VAR LH + KRR+ PFV +N AIP +L+ESELFGHEKGAFTGA T GRFE A Sbjct: 171 TGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQA 230 Query: 238 NGGTLFLDEIGDMPLPMQVKLLRVLQERTFERVGSNKTQSIDVRIIAATHKNLENMIELG 297 GGTLFLDEIGDMP+ Q +LLRVLQ+ + VG DVRI+AAT+K+L+ I G Sbjct: 231 EGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQG 290 Query: 298 SFREDLYYRLNVFPIEMAPLRERVEDIPLLMNELISRMEHEKRGSIRFNSAAIMSLCRHA 357 FREDLYYRLNV P+ + PLR+R EDIP L+ + + E E RF+ A+ + H Sbjct: 291 LFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHP 350 Query: 358 WPGNVRELANLVERMAIMHPYGVIGVAELPKKFRY-VDDEDEQMVDSMRSDIEERVAINS 416 WPGNVREL NLV R+ ++P VI + + R + D + + + A+ Sbjct: 351 WPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEE 410 Query: 417 NTPN-FASGAMLPPEGLDLKDYLGGLEQGLIQQALDDANGIVARAAERLRIRRTTLVEKM 475 N FAS P L +E LI AL G +AA+ L + R TL +K+ Sbjct: 411 NMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKI 470 Query: 476 RKYGMSRREGDEQA 489 R+ G+S A Sbjct: 471 RELGVSVYRSSRSA 484
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 493 bits (1271), Expect = e-174 Identities = 172/477 (36%), Positives = 250/477 (52%), Gaps = 20/477 (4%) Query: 5 VLLVEDDRSLREALGETLELAGYGYQAVGSAEEALVAAEAQPFSLVISDVNMPGMDGHQL 64 +L+ +DD ++R L + L AGY + +A A LV++DV MP + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 65 LSLLRSRHPQLPVLLMTAHGAVDRAVDAMRQGAADYLVKPFEP--------KALIALVAR 116 L ++ P LPVL+M+A A+ A +GA DYL KPF+ +AL R Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 117 HALGRLGPAESDGPIAVEPASIQLLNLASRVAKSDSTVLISGESGTGKEVLARFIHQNSP 176 + + + A ++ + +R+ ++D T++I+GESGTGKE++AR +H Sbjct: 126 PSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGK 185 Query: 177 RADKPFIAINCAAIPDNMLEATLFGHEKGSFTGAIAAQAGKFEQADGGTILLDEISEMPM 236 R + PF+AIN AAIP +++E+ LFGHEKG+FTGA G+FEQA+GGT+ LDEI +MPM Sbjct: 186 RRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPM 245 Query: 237 GLQAKLLRVLQEREVERVGARKPITLDIRVVATTNRDLAGEVAAGRFREDLFYRLSVFPL 296 Q +LLRVLQ+ E VG R PI D+R+VA TN+DL + G FREDL+YRL+V PL Sbjct: 246 DAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPL 305 Query: 297 AWQALRQRTADILPLAERLLAKHVNKMKHAPVRLSAQAQQCLVSYPWPGNVRELDNAVQR 356 LR R DI L + + K R +A + + ++PWPGNVREL+N V+R Sbjct: 306 RLPPLRDRAEDIPDLVRHFVQQ-AEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRR 364 Query: 357 ALILQQGGVIEAQDFCLAGPVTSLPVAVPSEAVPPQPVISSAEN--------AGVGVGAE 408 L VI + + A + S A G Sbjct: 365 LTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALP 424 Query: 409 SAGALGDDLRRREFQMIIDTLRAERGRRKEAAERLGISPRTLRYKLAQMRDAGMDVE 465 +G L E+ +I+ L A RG + +AA+ LG++ TLR K +R+ G+ V Sbjct: 425 PSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKK---IRELGVSVY 478
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 78.2 bits (192), Expect = 2e-22 Identities = 38/92 (41%), Positives = 52/92 (56%) Query: 27 QMDAMSAPKPVSGAQEAGASSFADMLGQAVNKVAQTQQASSQLANAFEVGKSGIDLTDVM 86 Q+ A + + SFA L A+++++ TQ A+ A F +G+ G+ L DVM Sbjct: 12 QLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVM 71 Query: 87 ISSQKASVSFQALTQVRNKLVQAYQDIMQMPV 118 QKASVS Q QVRNKLV AYQ++M M V Sbjct: 72 TDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 513 bits (1323), Expect = e-179 Identities = 197/576 (34%), Positives = 300/576 (52%), Gaps = 40/576 (6%) Query: 27 LENLSEMTMLRQIGLMVGLAASVAIGFAVVLWSQQPDYRPLYGSLAGMDSKQIMDTLTAA 86 LE L+ + +I L+V +A+VAI A+VLW++ PDYR L+ +L+ D I+ LT Sbjct: 13 LEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQM 72 Query: 87 NINYTVEPNSGALLVKSDDVQRARIQLAQAGVVQNDANIGFEILDKDQGLGTSQFMEATR 146 NI Y SGA+ V +D V R++LAQ G+ + +GFE+LD+++ G SQF E Sbjct: 73 NIPYRFANGSGAIEVPADKVHELRLRLAQQGLPK-GGAVGFELLDQEK-FGISQFSEQVN 130 Query: 147 YRRGLEGELARTISALNNVKGARVHLAIPKSSVFVRDDRKPSASVLVELYAGRSLEPSQV 206 Y+R LEGELARTI L VK ARVHLA+PK S+FVR+ + PSASV V L GR+L+ Q+ Sbjct: 131 YQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQI 190 Query: 207 LAIINLVATSVPELSKSQITVVDQKGTLLSDQAENSELTMAGKQFDYSRRMEGMLTQRVQ 266 A+++LV+++V L +T+VDQ G LL+ Q+ S + Q ++ +E + +R++ Sbjct: 191 SAVVHLVSSAVAGLPPGNVTLVDQSGHLLT-QSNTSGRDLNDAQLKFANDVESRIQRRIE 249 Query: 267 NILQPILGNDRYKAEVSAVVDFSAVESTAESFNPDQPA----LRSEQSVNEQRSSSSSTG 322 IL PI+GN A+V+A +DF+ E T E ++P+ A LRS Q ++ + G Sbjct: 250 AILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPG 309 Query: 323 GVPGALSNQPPGPATAPQNAAAGAAGAAGPIAPGQPLLDANGQQIMDPATGQPALAPYPA 382 GVPGALSNQP P AP P N Q +T + + P Sbjct: 310 GVPGALSNQPAPPNEAPIAT--------------PPTNQQNAQNTPQTSTSTNSNSAGPR 355 Query: 383 DKRVQSTKNFELDRSISHTKQQQGRLTRLSVAVVVDDMVKTNAANGEVSRAPWSAADLAR 442 + T N+E+DR+I HTK G + RLSVAVVV+ + P +A + + Sbjct: 356 STQRNETSNYEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKP-----LPLTADQMKQ 410 Query: 443 FTRLVQDAVGFDASRGDSVSVINVPFSSERAEVLPEASFYSQPWFWDIVKQAVGVIFILI 502 L ++A+GF RGD+++V+N PFS+ E F+ Q F D + A + +L+ Sbjct: 411 IEDLTREAMGFSDKRGDTLNVVNSPFSAV-DNTGGELPFWQQQSFIDQLLAAGRWLLVLV 469 Query: 503 LVF----GVLRPVLNNITSG-KSKELAGFGGDAELGGMGGLDGELSNDRVSLGGPQSILL 557 + + +RP L K+ + ++ LS D + L Sbjct: 470 VAWILWRKAVRPQLTRRVEEAKAAQEQAQVRQE---TEEAVEVRLSKDEQLQQRRANQRL 526 Query: 558 PSPTEGYDAQLNAIKSLVAEDPGRVAQVVKEWINTD 593 G + I+ + DP VA V+++W++ D Sbjct: 527 -----GAEVMSQRIREMSDNDPRVVALVIRQWMSND 557
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 299 bits (768), Expect = e-103 Identities = 105/332 (31%), Positives = 204/332 (61%) Query: 2 VAKLSKVEKAAVLLLSLGETDAAQVLRHMGPKEVQKVGVAMAQMRNVHREQVEEVMSEFV 61 V+ L+ +KAA+LL+S+G +++V +++ +E++ + +A++ + E + V+ EF Sbjct: 12 VSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFK 71 Query: 62 DIVGDQTSLGVGSDGYIRKMLTQALGEDKANGLIDRILLGGNTSGLDSLKWMEPRAVADV 121 +++ Q + G Y R++L ++LG KA +I+ + + + ++ +P + + Sbjct: 72 ELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSRPFEFVRRADPANILNF 131 Query: 122 IRFEHPQIQAIVVAYLDADQAGEVLGHFDHKVRLDIILRVSSLNTVQPAALKELNQILEK 181 I+ EHPQ A++++YLD +A +L +V+ ++ R++ ++ P ++E+ ++LEK Sbjct: 132 IQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLEK 191 Query: 182 QFSGNANTSRTTLGGIKRAADIMNFLDSSIEGALMDSIREVDEDLSVQIEDLMFVFNNLS 241 + + ++ T+ GG+ +I+N D E +++S+ E D +L+ +I+ MFVF ++ Sbjct: 192 KLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDIV 251 Query: 242 DVDDRGIQALLREVSSDVLVLALKGSDEAIKEKIFKNMSKRAAELLRDDLEAKGPVRVSD 301 +DDR IQ +LRE+ L ALK D ++EKIFKNMSKRAA +L++D+E GP R D Sbjct: 252 LLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRKD 311 Query: 302 VETAQKEILTIARRMAEAGEIVLGGKGGEEMI 333 VE +Q++I+++ R++ E GEIV+ G E+++ Sbjct: 312 VEESQQKIVSLIRKLEEQGEIVISRGGEEDVL 343
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 139 bits (353), Expect = 2e-42 Identities = 97/256 (37%), Positives = 151/256 (58%), Gaps = 2/256 (0%) Query: 1 MLALTDIQISTWVASFMLPMFRIVALLMTMPVIGTTLVPRRVRLYLAFAITVVVAPALPA 60 ML +T Q +W+ + P+ R++AL+ T P++ VP+RV+L LA IT +AP+LPA Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 Query: 61 MPPVQALDLSGLLLIGEQIIIGAGMGLSLQMFFHIFVIAGQIISTQMGMGFASMVDPTNG 120 L L +QI+IG +G ++Q F AG+II QMG+ FA+ VDP + Sbjct: 61 NDVPV-FSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASH 119 Query: 121 VSSAVIGQFFTMLVTLLFLSMNGHLVALEILVESFTTMPVGGGLLVNNFWELANGLGWAL 180 ++ V+ + ML LLFL+ NGHL + +LV++F T+P+GG L +N + G + Sbjct: 120 LNMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLI 179 Query: 181 -SAGLRLVLPAVTALLIINIAFGVMTRAAPQLNIFSIGFPLTLVLGMVILWMTMGDILNQ 239 GL L LP +T LL +N+A G++ R APQL+IF IGFPLTL +G+ ++ M I Sbjct: 180 FLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPF 239 Query: 240 YQPIATQALQMLRDMV 255 + + ++ +L D++ Sbjct: 240 CEHLFSEIFNLLADII 255
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 311 bits (799), Expect = e-106 Identities = 95/346 (27%), Positives = 175/346 (50%), Gaps = 4/346 (1%) Query: 9 DKTEDPTEKKVKDSRAEGQIARSKELTTLVVMLMGAGGLLMFGAGIAQMMSDLMRDNFTI 68 +KTE PT KK++D+R +GQ+A+SKE+ + +++ + L+ + S LM Sbjct: 4 EKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLML---IP 60 Query: 69 SRETIMDQSYMGKALLSSGL-HALVVMLPFLIAMLAAALVGPILLGGWLFSTKSLMPKFS 127 + ++ + S ++ + L + P L A+ ++ G+L S +++ P Sbjct: 61 AEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIK 120 Query: 128 RMNPAAGLKRMFSPHALVELLKSFGKFLIILAVALVVLSKERNDLVAIAHEPLEQAMIHS 187 ++NP G KR+FS +LVE LKS K +++ + +++ L+ + +E Sbjct: 121 KINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLL 180 Query: 188 LLVVGWSSFWMACGLMFIAAADVPFVLYEAHKKLLMTKQEVRDEHKNSEGSPEVKQRIRQ 247 ++ G + I+ AD F Y+ K+L M+K E++ E+K EGSPE+K + RQ Sbjct: 181 GQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQ 240 Query: 248 LQREMSQRRMMASIPEADVIITNPTHFAVALKYDPEQGGAPMLLAKGTDLVALKIREIGA 307 +E+ R M ++ + V++ NPTH A+ + Y + P++ K TD +R+I Sbjct: 241 FHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAE 300 Query: 308 HNQILILESAALARSIYYSTELDQEIPAGLYLAVAQVLAYVYQIRQ 353 + IL+ LAR++Y+ +D IPA A A+VL ++ + Sbjct: 301 EEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNI 346
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.0 bits (218), Expect = 1e-23 Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 3/123 (2%) Query: 2 KILIVDDFSTMRRIIKNLLRDLGFTNTSEADDGLTALPMLQSGAFDFLVTDWNMPGMTGI 61 IL+ DD + +R ++ L G+ + T + +G D +VTD MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 DLLRQVRADDRLKSLPVLMVTAEAKREQIIEAAQAGVNGYVVKPFTAQALKEKIEKIFER 121 DLL +++ LPVL+++A+ I+A++ G Y+ KPF L I + Sbjct: 64 DLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 122 VNS 124 Sbjct: 122 PKR 124
>PF06580#Sensor histidine kinase Length = 349 Score = 47.6 bits (113), Expect = 1e-07 Identities = 16/79 (20%), Positives = 32/79 (40%), Gaps = 10/79 (12%) Query: 456 ETDLDKNLVEALADPLV--HLVRNAVDHGIETPEEREASGKSRGGKVILSAEQEGDHILL 513 E ++ +++ P++ LV N + HGI +GGK++L ++ + L Sbjct: 243 ENQINPAIMDVQVPPMLVQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTL 294 Query: 514 SISDDGKGMDPNVLRSIAV 532 + + G N S Sbjct: 295 EVENTGSLALKNTKESTGT 313
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 60.2 bits (146), Expect = 5e-12 Identities = 31/147 (21%), Positives = 54/147 (36%), Gaps = 7/147 (4%) Query: 2 AVKVLVVDDSGFFRRRVTEILSSDPNIVVVGTATNGKEAIEQALALKPDVITMDYEMPMM 61 +LV DD R + + LS V +N A D++ D MP Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVR--ITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 62 DGITAVRHIMQRIP-TPVLMFSSLTHEGARVTLDALDAGAVDFLPKNF--EDISRNPQKV 118 + + I + P PVL+ S+ + A + GA D+LPK F ++ + Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAI--KASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 119 KQLLCEKINSISRSNRRSSGIGSASAA 145 + + + ++ + SAA Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAA 145
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 61.5 bits (149), Expect = 6e-13 Identities = 32/128 (25%), Positives = 54/128 (42%), Gaps = 16/128 (12%) Query: 134 LNSSLLFVSGDAMPSDKAFTIIEKVSGIVKRFDNP---IHVEGFTDDQPISTAQFPTNWE 190 L S +LF A + ++++ + D + V G+TD I + + N Sbjct: 217 LKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDR--IGSDAY--NQG 272 Query: 191 LSSARSASIVRMLAMDGINPARLASVGYGEFQPIAPNTTAAGR---------AKNRRVVL 241 LS R+ S+V L GI ++++ G GE P+ NT + A +RRV + Sbjct: 273 LSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEI 332 Query: 242 VISRNLDV 249 + DV Sbjct: 333 EVKGIKDV 340
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 270 bits (691), Expect = 2e-80 Identities = 207/741 (27%), Positives = 307/741 (41%), Gaps = 98/741 (13%) Query: 125 NIHGAVVSNDSGFGIS-LGGIIDSDKPGSEASIFSSNVSGLEVGIAVGLWGELNLVNTEL 183 + + + D G I L + D P S + +NV+ + A L L Sbjct: 172 TVQRSAIV-DGGLHIGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPAAVSVLGASELTL 230 Query: 184 HGAASQRGRGQGILSSGGNVFITQRSHVMGD-------LNGINITDGSAR-GSSDGSL-- 233 G GR G+ + G V QR+ + + G + G+ G G Sbjct: 231 DGGHITGGRAAGVAAMQGAVVHLQRATIRRGDAPAGGAVPGGAVPGGAVPGGFGPGGFGP 290 Query: 234 IGNKPYTV--------INDSIVEGL-TGAAIRVDQRVLFDIDADIAVQNHSELLSGNGNL 284 + + Y V + SIVE GAAIRV + + H ++ G Sbjct: 291 VLDGWYGVDVSGSSVELAQSIVEAPELGAAIRVGRGARVTVSGGSLSAPHGNVIETGGAR 350 Query: 285 LEVADSSTVNFNV-DNSTLNGN--LVADDTSTLNVTLQNGAQLNGDII------------ 329 ++ ++ + + G L + +TL GA GDI+ Sbjct: 351 RFAPQAAPLSITLQAGAHAQGKALLYRVLPEPVKLTLTGGADAQGDIVATELPSIPGTSI 410 Query: 330 -------------NGNTLAITS----GGQWQMQGDNAVTSLSMQG-GSVGFGGEG----F 367 G T A+ S W M ++ V +L + GSV F F Sbjct: 411 GPLDVALASQARWTGATRAVDSLSIDNATWVMTDNSNVGALRLASDGSVDFQQPAEAGRF 470 Query: 368 HTLSLNELSGSGTFGLRVDLDNAVGDLINVNGQASGQFGLRVRNTGVEVISADMQPLKVV 427 L++N L+GSG F + V D + D + V ASGQ L VRN+G E SA+ L V Sbjct: 471 KVLTVNTLAGSGLFRMNVFADLGLSDKLVVMQDASGQHRLWVRNSGSEPASANTLLL-VQ 529 Query: 428 HTEGGDAQFSL--LGGRVDLGAYSYLLEQQGN-DWFVVGRDKVISPSTQ----------- 473 G A F+L G+VD+G Y Y L GN W +VG +P Sbjct: 530 TPLGSAATFTLANKDGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPP 589 Query: 474 -------------------SALALYSA-----APAIWMSELSTLRSRMGEVRASGQAGG- 508 +A A + A +W +E + L R+GE+R + AGG Sbjct: 590 QPQPEAPAPQPPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRLNPDAGGA 649 Query: 509 WMRAYGSRLNATTSDGVDYRQKQSGLSLGADAPVEVSNGRLLVGVLGGYSTSDLDVSRGT 568 W R + R G + QK +G LGAD V V+ GR +G L GY+ D + Sbjct: 650 WGRGFAQRQQLDNRAGRRFDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDRGFTGDG 709 Query: 569 TGKVASYYAGAYGTWLSDDGYYVDGVLKLNRFRNKADVAMSDASKAKGDYSNTGVGGWVE 628 G S + G Y T+++D G+Y+D L+ +R N VA SD KG Y GVG +E Sbjct: 710 GGHTDSVHVGGYATYIADSGFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGASLE 769 Query: 629 AGRHIKLADDYFLEPFAQLSSVVVQGQELRLDNGMKAKNARTRSVLGKVGTSLGRTVALK 688 AGR AD +FLEP A+L+ G R NG++ ++ SVLG++G +G+ + L Sbjct: 770 AGRRFTHADGWFLEPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLEVGKRIELA 829 Query: 689 DGGVLQPYVRVAVAQEFSRRNEVKANDVKFDNSLFGSRGELGAGVSVSLSERLKLHADVD 748 G +QPY++ +V QEF V N + L G+R ELG G++ +L L+A + Sbjct: 830 GGRQVQPYIKASVLQEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALGRGHSLYASYE 889 Query: 749 YMKGQHIEQPWGANVGLRLTF 769 Y KG + PW + G R ++ Sbjct: 890 YSKGPKLAMPWTFHAGYRYSW 910
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 30.5 bits (68), Expect = 0.020 Identities = 36/180 (20%), Positives = 68/180 (37%), Gaps = 11/180 (6%) Query: 238 RLKTCLTRLQDTAEHLNNQARQANSLANASSTGLERQRVETEQVA-AAINQMAATTQEVA 296 + T + + L + SL + + G + EQ A A + Sbjct: 149 KTDTAKSVYDAATKKLTQAQNKLQSL-DPADPGYAQAEAAVEQAGKEATEAKEALDKATD 207 Query: 297 SHVNRAADATQQANELTRRGRDIAGETREAIQRLSTSVGETGLTVTRLAKDSDEIGGVVD 356 + V DA +A + G A Q + + L+ +A+ + + ++ Sbjct: 208 ATVKAGTDAKAKAEKADNILTKFQGTANAASQNQVSQGEQDNLS--NVARLTMLMAMFIE 265 Query: 357 VIKGIADQT--NLLALNAAIEAARAGEMGRGFAVVADEVRQLAQRTAESTGQIHGLIAKL 414 ++ +++ N LAL A++ R EM + A +E R+ AE T +I G I K+ Sbjct: 266 IVGKNTEESLQNDLALFNALQEGRQAEMEKKSAEFQEETRK-----AEETNRIMGCIGKV 320
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 30.4 bits (68), Expect = 0.039 Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 6/83 (7%) Query: 679 IEDARILALLGDSVTTDHISPAGNIKADSPAGRYLQEKGVAYQDFNSYGSRRGNHEVMMR 738 I+DAR + L + V T++ S N P + Y+ F G + N + + Sbjct: 192 IDDARTIFSLANIVNTNNNSADVN-----PKEDGIGYFTNVYESFQRLGLTKSNLDSIFV 246 Query: 739 GTFANIRIRNEMLGGEEGGNTVH 761 + +NI I NE+ G G V+ Sbjct: 247 NSDSNIVI-NELASGRRQGGIVY 268
>PF01206#SirA family protein Length = 76 Score = 86.4 bits (214), Expect = 2e-26 Identities = 24/72 (33%), Positives = 42/72 (58%) Query: 10 VDAVLDATGLFCPEPVMMLHQKVRDLPPSGLLKVIATDPSTCRDIPKFCVFLGHELVAEQ 69 D LDATGL CP P++ + + + +L V+ATDP + +D F GHEL+ ++ Sbjct: 4 FDQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQK 63 Query: 70 AEESTFLYWIRK 81 E+ T+ + +++ Sbjct: 64 EEDGTYHFRLKR 75
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 29.0 bits (64), Expect = 0.010 Identities = 36/126 (28%), Positives = 53/126 (42%), Gaps = 20/126 (15%) Query: 34 DSQWQAKWSEQVSAQSQAVATTTAE--YRTEEQRRQKAANQVANDARQEQTAALTDAAVA 91 ++ AK S + +A ++A AE + EEQ RQ+AA + AN A + +V Sbjct: 205 NTLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAAN-----TYAMPANGSVV 259 Query: 92 DAAGGRLRIEAGKLAATAGCVPGDTGASERGKAATRAAMVLSDLLGRADS-RAGELAKAY 150 A GR I+ + GA+ +A + A VL +L A S A A Sbjct: 260 ATAAGRGLIQVAQ------------GAASLAQAISDAIAVLGRVLASAPSVMAVGFASLT 307 Query: 151 DQSRVA 156 SR A Sbjct: 308 YSSRTA 313
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 24.8 bits (54), Expect = 0.031 Identities = 18/79 (22%), Positives = 27/79 (34%), Gaps = 31/79 (39%) Query: 10 YMGETMLIVKANG-GTVTVEKKAGDNWVVTDTFAKDGGYLL------------------- 49 + +T+++VKA G VE + G V TD GY + Sbjct: 713 PLNDTVVLVKAPGAKDAKVENQTG---VRTDWR----GYAVLPYATEYRENRVALDTNTL 765 Query: 50 ----QLGNSSTRITPYAGA 64 L N+ + P GA Sbjct: 766 ADNVDLDNAVANVVPTRGA 784
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 132 bits (332), Expect = 1e-39 Identities = 82/253 (32%), Positives = 125/253 (49%), Gaps = 15/253 (5%) Query: 7 LAGKVALVQGGSRGIGAAIVNRLAKEGAAVAFTYINSEVNALEIQDSINANGGRALAIRA 66 + GK+A + G ++GIG A+ LA +GA +A N E + S+ A A A A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVS-SLKAEARHAEAFPA 64 Query: 67 DSADEKAIRQAVQTTAETLGRLDILVNNAGVLAIAPLNEFSMQDFDKTLAINVRSVFIAS 126 D D AI + +G +DILVN AGVL ++ S ++++ T ++N VF AS Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 127 QEAARHM--EEGGRIINIGSTNAERMPFAGGATYAMSKSALIGLTKGMARDLGPQGITVN 184 + +++M G I+ +GS N +P A YA SK+A + TK + +L I N Sbjct: 125 RSVSKYMMDRRSGSIVTVGS-NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 185 NVQPGPVDTDMNPA-----QGE------FAESLKALMALPRYGKSEEIASFVAYLAGPEA 233 V PG +TDM + G E+ K + L + K +IA V +L +A Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 234 GYITGASLTIDGG 246 G+IT +L +DGG Sbjct: 244 GHITMHNLCVDGG 256
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 45.8 bits (108), Expect = 2e-08 Identities = 44/194 (22%), Positives = 73/194 (37%), Gaps = 29/194 (14%) Query: 5 DNSALILIDMQQGINHP-KLGRRNNPQAETNIGALLSAWRQSGRPVIHVRH-FSTSPE-- 60 + + L++ DMQ G + NI L + Q G PV++ S +P+ Sbjct: 29 NRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDDR 88 Query: 61 ---SVFW-PEQSGVEYQPAFV----PHADERELSKQVPDAFCGSFLEMWLRSDGIRQVVI 112 + FW P + Y+ + P D+ L+K AF + L +R +G Q++I Sbjct: 89 ALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLII 148 Query: 113 VGVVTNNPIESTARSGGNLGFGVVVAHDACFTFDQKDFF---GTPRSAEDVHAMSLANVH 169 G+ + G +V F D K FF + + H M+L Sbjct: 149 TGIYAH--------------IGCLVTACEAFMEDIKAFFVGDAVADFSLEKHQMALEYAA 194 Query: 170 GEYATVLSTAQVLQ 183 G A + T +L Sbjct: 195 GRCAFTVMTDSLLD 208
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 42.9 bits (101), Expect = 1e-06 Identities = 75/401 (18%), Positives = 141/401 (35%), Gaps = 59/401 (14%) Query: 9 SQQKLKSSFLLLFLTIFIPFGLGHFVSYLFRTVNAVIYVDLQTDLSLPASSLGLLTGVYF 68 SQ L+ + +L++L I F S L V V D+ D + P +S + + Sbjct: 6 SQSNLRHNQILIWLCILS------FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFM 59 Query: 69 LTFAAAQIPLGVMLDRYGPRSVQAPMLLFAVAGSVIFSVSSTETGLLI-GRGLIGLGVAG 127 LTF+ G + D+ G + + ++ GSVI V + LLI R + G G A Sbjct: 60 LTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAA 119 Query: 128 SLMSAIKACAIWLPVERLPLSTACLLSIGGLGAMASTAPLHALLSWLTWREAFLVLALLT 187 + A ++P E + + SI +G A + ++ W L+ + Sbjct: 120 FPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITI 179 Query: 188 FCVVVVIHFSVPKAYESRNTRYSDMFAAV-----------GKLYSSWTFWRLALYS---- 232 V ++ E R + D+ + S +F +++ S Sbjct: 180 ITVPFLMKLLKK---EVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIF 236 Query: 233 ---------------VFAHAIYMSVLS-------------LWMGPWLRDMAGLSDSAMAS 264 + + +M + + ++D+ LS + + S Sbjct: 237 VKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGS 296 Query: 265 VLLFGAIAMVAGSLTFGAITDYL-RRFGLQPIMICGTGMVI--FIGFQVLMASGLPVSHY 321 V++F ++ + FG I L R G ++ G + F+ L+ + Sbjct: 297 VIIF--PGTMSV-IIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTI 353 Query: 322 LIAMGFSFFGTSTTMNYAIVAQSVSPELAGRVSSSFNLVVF 362 +I + T+ IV+ S+ + AG S N F Sbjct: 354 IIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSF 394
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.8 bits (80), Expect = 6e-04 Identities = 42/176 (23%), Positives = 69/176 (39%), Gaps = 26/176 (14%) Query: 36 AIAKTFFPSDSAFASLMLSLATFGAGFLMRPLGAIFSGAYIDRHGRRKGLIITLAMMAMG 95 + + S+ A + LA + LM+ A GA DR GRR L+++LA A+ Sbjct: 30 GLLRDLVHSNDVTAHYGILLALYA---LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVD 86 Query: 96 TLLIACVPGYATLGVIAPLLVLLGRLLQGFSAGVELGGVSVYLAEISTPGRKGFFVSWQS 155 ++A P L +GR++ G + G Y+A+I+ + + S Sbjct: 87 YAIMATAPFLWVL--------YIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMS 137 Query: 156 ASQQAAVVFAGLLGVGLNHWLSPEQMGEWGWRVPFLI-----GCLIVPAIFIIRRS 206 A +V +LG GL MG + PF G + F++ S Sbjct: 138 ACFGFGMVAGPVLG-GL--------MGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Score = 29.8 bits (67), Expect = 0.024 Identities = 11/33 (33%), Positives = 19/33 (57%) Query: 278 CVGVSNFIWLPIMGSFSDRIGRKPLLIAATVLA 310 + F P++G+ SDR GR+P+L+ + A Sbjct: 51 LYALMQFACAPVLGALSDRFGRRPVLLVSLAGA 83
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 25.6 bits (56), Expect = 0.030 Identities = 13/59 (22%), Positives = 21/59 (35%) Query: 4 RELQKQLDTLREQLEYNPPISESERDDLNELMQQIEMKIQLEQATHEQDSSLADGVNLA 62 + L LD ++E I + D L EL + I+ + D N+A Sbjct: 269 QRLIHALDKPSARIEVALSIVDINADQLTELGVDWRVGIRTGNNHQVVIKTTGDQSNIA 327
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 229 bits (585), Expect = 5e-78 Identities = 68/229 (29%), Positives = 108/229 (47%), Gaps = 16/229 (6%) Query: 18 CAGMALVPVAV---------QAAESDPWEGINRSIFSFN-DTLDAYTLKPLAKGYQYIAP 67 + +AL + Q SDP EG NR++++FN + LD Y ++P+A ++ P Sbjct: 5 LSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWRDYVP 64 Query: 68 QFVEDGIHNFFSNIGDVGNLANNVLQAKPEAAGVDTARLIVNTTFGLLGFIDVGTRMGLQ 127 Q +G+ NF N+ + + N LQ P V R +NT G+ GFIDV + Sbjct: 65 QPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGMANPK 124 Query: 128 RS---DEDFGQTLGYWGVPSGPFVVIPLLGPSTVRDAIAKYPDTYTSPYRYIDHVPTRNT 184 FG TLG++GV GP+V +P G T+RD D ++ + Sbjct: 125 LQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSWLTWPMSVGK 184 Query: 185 ALGVNLVDTRASLLSAERLV--SGDRYTFIRNAYLQNREFKVKDGQVED 231 + ++TRA LL ++ L+ S D Y +R AY Q +F G+++ Sbjct: 185 W-TLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKP 232
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 115 bits (289), Expect = 2e-30 Identities = 41/125 (32%), Positives = 59/125 (47%), Gaps = 1/125 (0%) Query: 4 TSAKLLIIDDDDVVRASLAAYLEDSGFSVLQASNGLQGIQIFEQENPDLVVCDLRMPQMG 63 T A +L+ DDD +R L L +G+ V SN + + DLVV D+ MP Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 64 GLELIRQVTAIAPQTPVIVVSGAGVMSDAVEALRLGAADYLIKPLEDLAVLEHSVRRALD 123 +L+ ++ P PV+V+S A++A GA DYL KP DL L + RAL Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF-DLTELIGIIGRALA 120 Query: 124 RSRLL 128 + Sbjct: 121 EPKRR 125
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 29.2 bits (65), Expect = 0.012 Identities = 22/85 (25%), Positives = 36/85 (42%), Gaps = 8/85 (9%) Query: 9 KKFTTVVADTGDFGAIKSLKPQDATTNPSLLLKAASSESNDQMLADAFSGAKGDIGLACD 68 K FT + G +K + T S+L+ S+ S D +L ++ IG Sbjct: 64 KDFTVDMNCPYSLGTMKVTITSNGQTGNSILVPNTSTASGDGLLIYLYNSNNSGIGN--- 120 Query: 69 RFAVAIGQEILKVVPGRVSTEVDAR 93 AV +G + V PG+++ AR Sbjct: 121 --AVTLGSQ---VTPGKITGTAPAR 140
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.2 bits (190), Expect = 2e-19 Identities = 39/128 (30%), Positives = 63/128 (49%), Gaps = 7/128 (5%) Query: 1 MSGDFRILIIDDQRPNLDLMEQLLAREGLTNVL-SSTEPLRTLDLFNSFEPDLVVLDLHM 59 M+G IL+ DD ++ Q L+R G + S+ L + + DLVV D+ M Sbjct: 1 MTG-ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATL--WRWIAAGDGDLVVTDVVM 57 Query: 60 PDFDGFAVLEQLNRRIPANDYLPIMVLTADATRDTRLRALALGARDFISKPLDALETMLR 119 PD + F +L ++ + P LP++V++A T T ++A GA D++ KP D E + Sbjct: 58 PDENAFDLLPRIKKARP---DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGI 114 Query: 120 IWNLLETR 127 I L Sbjct: 115 IGRALAEP 122
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.1 bits (156), Expect = 9e-13 Identities = 25/122 (20%), Positives = 53/122 (43%), Gaps = 3/122 (2%) Query: 624 GKLLCIEDNLSSMALIETLLQRRPGIQLLSSMQGQLGLDLARQHAPQLILLDLNLPDIKG 683 +L +D+ + ++ L R G + + L++ D+ +PD Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 684 LEVLQRLRRLPATANTPVLMITADASVNAQRELKEAGATAILIKPIQVPVFLALLDQYLP 743 ++L R+++ A + PVL+++A + + E GA L KP + + ++ + L Sbjct: 63 FDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 744 EP 745 EP Sbjct: 121 EP 122
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 134 bits (339), Expect = 9e-39 Identities = 80/311 (25%), Positives = 114/311 (36%), Gaps = 65/311 (20%) Query: 59 GYFLTDDVELRLGYD-----EVHNVRSDDGKNIKGANTALDALYHFNNPGDMLRPYVSAG 113 GY + V +GYD + +G Y D L Y G Sbjct: 63 GYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPIT---DDLDIYTRLG 119 Query: 114 ----FSDQSIGQNGRNGRNGSTFANIGGGAKLYFTDNFYARAGVEAQYNI-DQGDTEWAP 168 +D G+N G + GG + T R + NI D P Sbjct: 120 GMVWRADTKSNVYGKNHDTGVSPV-FAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRP 178 Query: 169 -----SVGIGVNFGGGS--KKVEAAPAPVAEVCSDSDNDGVCDNVDKCPDTPANVTVDAD 221 S+G+ FG G V APAP EV + Sbjct: 179 DNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKH------------------------ 214 Query: 222 GCPAVAEVVRVELDVKFDFNKSVVKPNSMGDIKNLADFMQQY--PQTTTTVEGHTDSVGP 279 ++ DV F+FNK+ +KP + L + + V G+TD +G Sbjct: 215 --------FTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGS 266 Query: 280 DAYNQKLSERRANAVKQVLVNQYGVGASRVNSVGYGESRPVADNATDAGR---------A 330 DAYNQ LSERRA +V L+++ G+ A ++++ G GES PV N D + A Sbjct: 267 DAYNQGLSERRAQSVVDYLISK-GIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLA 325 Query: 331 VNRRVEAEVEA 341 +RRVE EV+ Sbjct: 326 PDRRVEIEVKG 336
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 42.8 bits (100), Expect = 3e-06 Identities = 37/116 (31%), Positives = 55/116 (47%), Gaps = 9/116 (7%) Query: 334 LATRVLRATGLLHRRNIIHRDIKPENLLLGN-DGELRLLDFGLAFCPGLSATNAEDLPG- 391 +A R+L T L + ++H DIKP N++ GE ++D GL + + E G Sbjct: 250 IAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDL------GLHSRSGEQPKGF 303 Query: 392 TPSYIAPE-AFNGAEAHPRQDLYAVGVTLYYLLTGHYPYGEIEAFQHRRFGTPIPA 446 T S+ APE A + D++ V TL + + G EI+ Q RF T PA Sbjct: 304 TESFKAPELGVGNLGASEKSDVFLVVSTLLHCIEGFEKNPEIKPNQGLRFITSEPA 359
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 61.0 bits (148), Expect = 3e-12 Identities = 94/461 (20%), Positives = 164/461 (35%), Gaps = 81/461 (17%) Query: 1 MDTSFWKAG--HRPTLFAAFLYFDLSFMVWYLLGPMAVQIATDLHLTTQQRGLMVATPIL 58 M+TS+ ++ H L + S + +L IA D + + +L Sbjct: 1 MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFML 60 Query: 59 AGAVLRLFMGLLADQLSPKTAGIIGQVI-VIGALFTAWQLGIHSYEQVLLLGLFLGMAGA 117 ++ G L+DQL K + G +I G++ HS+ +L++ F+ AGA Sbjct: 61 TFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVG---HSFFSLLIMARFIQGAGA 117 Query: 118 SFAVALPLA--SQWYPPQHQGKAMG-IAGAGNSGTVLAALIAPVLAASFGWGNVFGLALI 174 + AL + +++ P +++GKA G I G + I ++A W + LI Sbjct: 118 AAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL---LI 174 Query: 175 PLVLTLIAFTLMARNAPERSKPKSMADYLKAL------------GDRDSWWFMFFYSVTF 222 P++ + LM + + + K D + S F+ ++F Sbjct: 175 PMITIITVPFLM-KLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSF 233 Query: 223 GGFI------------------------------------GLASALPGYFNDQYGLSPIT 246 F+ G S +P D + LS Sbjct: 234 LIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAE 293 Query: 247 AGYYT--AACVFGGSLMRPLGGALADRFGGIRTLTVMYTVAAVGIAAVGFNLPSS-WAAL 303 G + + +GG L DR G + L + T +V F L ++ W Sbjct: 294 IGSVIIFPGTMSVI-IFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMT 352 Query: 304 ALFVAAMLGLGAGNGAVFQLVPQRFR-KEIGVMTGLI------GMAGGIG--GFLLAAGL 354 + V + GL + +V + +E G L+ GI G LL+ L Sbjct: 353 IIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPL 412 Query: 355 -------GAIKQNTGDYQLGLWLFAGLAVLAWFGLLNVKRR 388 + Q+T Y L LF+G+ V++W LNV + Sbjct: 413 LDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVYKH 453
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 45.2 bits (107), Expect = 6e-08 Identities = 26/135 (19%), Positives = 59/135 (43%), Gaps = 3/135 (2%) Query: 3 RILLINDTARKVGRLRSALTEAGFEVIDESGLIIDLPARVEAVRPDVILIDTESPGRDVM 62 IL+ +D A L AL+ AG++V S L + A D+++ D P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAA-TLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 EQVVLVSRDQPR-PIVMFTDEHDPGVMRQAIKSGVSAYIVEGIQAQRLQPILDVAMARFE 121 + + + + +P P+++ + ++ +A + G Y+ + L I+ A+A + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 122 SDQALRAQLHARDQQ 136 + + + ++D Sbjct: 124 RRPS-KLEDDSQDGM 137
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.9 bits (166), Expect = 1e-16 Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 7/120 (5%) Query: 4 TARTILVVEDDAIVRMLIVDVLEELEYTVLEAEDATTALAIVTDNANHIDLLMTDQGLPD 63 T TILV +DDA +R ++ L Y V +A T + A DL++TD +PD Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA--AGDGDLVVTDVVMPD 59 Query: 64 MKGTALAKKVIELRPELPVLFASGYSENIDVPPGMYA-----IGKPFSIDQLRDKVKSIL 118 L ++ + RP+LPVL S + + + KPF + +L + L Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.2 bits (190), Expect = 1e-16 Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 3/115 (2%) Query: 1047 KILVVDDDVRNIFALTSALEHKGAVVEIARNGLEAIAKLNEVEDIDLVLMDVMMPEMDGY 1106 ILV DDD L AL G V I N + D DLV+ DV+MP+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA-GDGDLVVTDVVMPDENAF 63 Query: 1107 EATIEIRKDPRWRKLPIIAVTAKAMKDDQERCLQAGSNDYLAKPIDLDRLFSLIR 1161 + I+K LP++ ++A+ + + G+ DYL KP DL L +I Sbjct: 64 DLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116 Score = 69.5 bits (170), Expect = 3e-14 Identities = 30/127 (23%), Positives = 54/127 (42%), Gaps = 5/127 (3%) Query: 780 ILVIEDEVRFAQILFDLAHELGYDCLVAHAADDGFNLASRYTPDAILLDMRLPDHSGLTV 839 ILV +D+ +L GYD + A + + D ++ D+ +PD + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 840 LQRLKELAPTRHIPVHVISVE---DRQEAALHMGAIGYAVKPTTREELKDVFAKLEAKLT 896 L R+K+ P +PV V+S + A GA Y KP EL + + A+ Sbjct: 66 LPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 897 QKVKRIL 903 ++ ++ Sbjct: 124 RRPSKLE 130 Score = 64.5 bits (157), Expect = 1e-12 Identities = 16/81 (19%), Positives = 32/81 (39%), Gaps = 2/81 (2%) Query: 901 RILLVEDDDLQRDSIARLIGDDDIEITAVGFAQQALDLLRDHIYDCMIIDLKLPDMLGNE 960 IL+ +DD R + + + ++ A + D ++ D+ +PD + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 961 LLKRMSTEDICAFPPVIVYTG 981 LL R+ PV+V + Sbjct: 65 LLPRIKKAR--PDLPVLVMSA 83
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 68.3 bits (167), Expect = 1e-14 Identities = 39/162 (24%), Positives = 63/162 (38%), Gaps = 11/162 (6%) Query: 7 AKLLIVDDLPENLLALEALIKRADRIVYKALSADEALSLLLQHEFALAILDVQMPGMNGF 66 A +L+ DD L + RA V +A + + L + DV MP N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 67 ELAEMMRSTEKTKSIPIVFVSAAGRELNYAFKGYESGAVDFLHKPLDIHAVKSKVNVFVD 126 +L ++ +P++ +SA A K E GA D+L KP D+ + Sbjct: 64 DLLPRIKKAR--PDLPVLVMSAQN-TFMTAIKASEKGAYDYLPKPFDL-------TELIG 113 Query: 127 LYRQRKAM-KIQVEELERSRQEQEVLLKRLQSTQGELEHAIR 167 + + A K + +LE Q+ L+ R + Q R Sbjct: 114 IIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLAR 155
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.2 bits (159), Expect = 1e-15 Identities = 32/121 (26%), Positives = 50/121 (41%), Gaps = 10/121 (8%) Query: 9 VLIVEDEPLILMLLADYLSGEGYRVLQAENGEQAFEILATKPHLDLMITDYRLPGGISGV 68 +L+ +D+ I +L LS GY V N + +A DL++TD +P + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAG-DGDLVVTDVVMPDE-NAF 63 Query: 69 QIAEPAVMLRPELKVIFISGYPAEILDSGSPI-ALKAPI---LAKPFTMETLQSQIQRLL 124 + RP+L V+ +S + I A + L KPF + L I R L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQN----TFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 125 A 125 A Sbjct: 120 A 120
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.5 bits (170), Expect = 2e-14 Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 9/118 (7%) Query: 559 TVLIVEDDPAVRALVSEVLSELGYAFIEASQATDAVPILESAQRIDLLISDVGLPGMNGR 618 T+L+ +DD A+R ++++ LS GY S A + + DL+++DV +P N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-GDLVVTDVVMPDENAF 63 Query: 619 QLAEIARQLRPALKVLFITGYAE----HAAVRAGFLDTGMELITKPFAFDHLTSKVRQ 672 L ++ RP L VL ++ A G D + KPF L + + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDY----LPKPFDLTELIGIIGR 117 Score = 46.0 bits (109), Expect = 4e-07 Identities = 23/116 (19%), Positives = 50/116 (43%), Gaps = 5/116 (4%) Query: 26 RILNEAGYPATAAADLFELVKELTAGAGLAIIADEALRNGDISPLLALLGQQPAWSDLPI 85 + L+ AGY ++ L + + AG G ++ D + + + LL + + A DLP+ Sbjct: 21 QALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRI--KKARPDLPV 78 Query: 86 VLLTHHGGPDHNPSARLGNMLGNVTFLERPFHPVTLVSLVTTAVRGRRRQYEARAR 141 ++++ A + G +L +PF L+ ++ A+ +R+ Sbjct: 79 LVMSAQNTFMTAIKA---SEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLED 131
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 39.8 bits (93), Expect = 2e-05 Identities = 18/133 (13%), Positives = 44/133 (33%), Gaps = 6/133 (4%) Query: 95 ALGTVT-ATNTINVRSRVAGELVKLYFQEGQKVKAGDLLAEIDPRSYQVALQQAEGTLAT 153 A G +T + + ++ + ++ +EG+ V+ GD+L ++ + + + +L Sbjct: 86 ANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQ 145 Query: 154 NQA--LLKNAQLDVQRYRGLFAEDSIAKQTLDTA-ESLVSQYQGTIKTNQAAVAD--AKL 208 + L + E V + IK + + + Sbjct: 146 ARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQK 205 Query: 209 SLDFTRIRAPIAG 221 L+ + RA Sbjct: 206 ELNLDKKRAERLT 218 Score = 33.6 bits (77), Expect = 0.001 Identities = 25/136 (18%), Positives = 51/136 (37%), Gaps = 17/136 (12%) Query: 144 LQQAEGTLATNQALLKNAQLDVQRYRGLFAEDSIAKQTLDTAESLVSQYQGTIKTNQAAV 203 L+ + L ++ + +A+ + Q LF + + K L + + A Sbjct: 268 LRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDK--LRQTTDNIGLLT-----LELAK 320 Query: 204 ADAKLSLDFTRIRAPIAGRV-GLKQLDVGNLVAANDTTALVVITQTQPISVAFTLPEKDL 262 + + + IRAP++ +V LK G +V +T +V++ + + V + KD Sbjct: 321 NEERQQA--SVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTALVQNKD- 376 Query: 263 SAVISRYRTGDKLPVE 278 I G Sbjct: 377 ---IGFINVG--QNAI 387
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 794 bits (2051), Expect = 0.0 Identities = 291/1032 (28%), Positives = 512/1032 (49%), Gaps = 28/1032 (2%) Query: 7 FIRRPVATVLLSLAIMLLGAVSFRLLPVAPLPNMDFPVIVVSASLAGASPEVMASTVATP 66 FIRRP+ +L++ +M+ GA++ LPVA P + P + VSA+ GA + + TV Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 67 LERSLGSIAGVNTMTSNS-SQGSTRIILQFDLNRDINGAAREVQAAINASRNLLPSGMRS 125 +E+++ I + M+S S S GS I L F D + A +VQ + + LLP ++ Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 126 MPTYKKVNPSQAPIMVLSMTST--VLEKGQLYDLASTILSQSLSQVSGVGEVQIGGSSLP 183 S + +MV S + + D ++ + +LS+++GVG+VQ+ G+ Sbjct: 125 QGISV-EKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY- 182 Query: 184 AVRIELEPQMLSQYGVSLDDVRTAITNANVRRPKGFV------EDDQHNWQVQANDQLES 237 A+RI L+ +L++Y ++ DV + N + G + Q N + A + ++ Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 238 AKDYAPLIIRY-QDGATLRLKDVAKVSDAVEDRYNSGFYNNDRAVLLVVNRQAGANIIET 296 +++ + +R DG+ +RLKDVA+V E+ N A L + GAN ++T Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 297 VAQIKAQLPALRAVLPASVSLNIAMDRSPVIKATLHEAEMTLLIAVVLVVMVVFLFLGSF 356 IKA+L L+ P + + D +P ++ ++HE TL A++LV +V++LFL + Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 357 RASLIPTLAVPVSLVGTFAIMHLFGFSLNNLSLMALILATGLVVDDAIVVLENISRHIH- 415 RA+LIPT+AVPV L+GTFAI+ FG+S+N L++ ++LA GL+VDDAIVV+EN+ R + Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 416 NGLDPMKAAFLGAKEVGFTLLSMNVSLVAVFISILFMGGLVESLFREFSITLSVSIVVSL 475 + L P +A ++ L+ + + L AVFI + F GG +++R+FSIT+ ++ +S+ Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 476 IVSLTLTPMLCARWLKPHVA---EKDNAFQRWSERVNDRMVAAYDRSLGWVLRHRRLTVL 532 +V+L LTP LCA LKP A E F W D V Y S+G +L +L Sbjct: 483 LVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLL 542 Query: 533 SLLVTVIVNVALYVVVPKTFLPQQDTGQLMGFVRGDDGLSFSVMQPKMEIFRRSVLADPA 592 + V V L++ +P +FLP++D G + ++ G + Q ++ L + Sbjct: 543 IYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEK 602 Query: 593 VE-----SVAGFIGGSGGTNNAFMIVRLKPIAER---KLSAEKVVERLRKNMPQVPGGRL 644 +V GF N V LKP ER + SAE V+ R + + ++ G + Sbjct: 603 ANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFV 662 Query: 645 FLAPDQDLQLGGGREQTSSQYQYIVQSADLASLRLWYPKIVA-ALKSIPELTAIDAREGR 703 + G + +L +++ A + L ++ Sbjct: 663 IPFNMPAIVELGTATGFDFELIDQ-AGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLE 721 Query: 704 GAQQVTLVVNRDTAKRLGIDMNMVTAVLNNAYSQRQVSTIYDSLNQYKVVMEVNPKYAQD 763 Q L V+++ A+ LG+ ++ + ++ A V+ D K+ ++ + K+ Sbjct: 722 DTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRML 781 Query: 764 PVTLEQVQLITADGQRVPLSSIAHYERSLANDRVSHDGQFAAENISFDLAEGASLDKATV 823 P ++++ + +A+G+ VP S+ + R+ + I + A G S A Sbjct: 782 PEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMA 841 Query: 824 AIERAIAAIGLPSDIISKMAGTANAFASTQKGQPWMILGSLLAVYLVLGILYESYIHPLT 883 +E + LP+ I G + + P ++ S + V+L L LYES+ P++ Sbjct: 842 LMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 884 ILSTLPSAGVGALLTIYVLGSEFSLISLLGLFLLIGLVKKNAIMMIDLALHLEREQGMTP 943 ++ +P VG LL + + + ++GL IGL KNAI++++ A L ++G Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 944 EESIRSACLQRLRPILMTTMAAILGALPLLLSTAEGAEMRKPLGLTIIGGLIFSQVLTLY 1003 E+ A RLRPILMT++A ILG LPL +S G+ + +G+ ++GG++ + +L ++ Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1004 TTPVVYLYLDRL 1015 PV ++ + R Sbjct: 1020 FVPVFFVVIRRC 1031 Score = 93.4 bits (232), Expect = 3e-21 Identities = 75/506 (14%), Positives = 168/506 (33%), Gaps = 31/506 (6%) Query: 2 NLSAPFIRRPVATVLLSLAIMLLGAVSFRLLPVAPLPNMDFPVIVVSASL-AGASPEVMA 60 N + +L+ I+ V F LP + LP D V + L AGA+ E Sbjct: 528 NSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQ 587 Query: 61 STVAT----------PLERSLGSIAGVNTMTSNSSQGSTRIILQFDLNRDINGAAREVQA 110 + S+ ++ G + + G + L+ + Sbjct: 588 KVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLK---PWEERNGDENSAE 644 Query: 111 AINASRNLLPSGMRSMPTYKKVNPSQAPIMVLSMTSTVLEK------GQLYDLASTILSQ 164 A+ + +R P+ + + L L + +L Sbjct: 645 AVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGM 704 Query: 165 SLSQVSGVGEVQIGGSS-LPAVRIELEPQMLSQYGVSLDDVRTAITNANVRRPKGFVEDD 223 + + + V+ G ++E++ + GVSL D+ I+ A D Sbjct: 705 AAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDR 764 Query: 224 QHNWQV--QANDQL-ESAKDYAPLIIRYQDGATLRLKDVAKVSDAVEDRYNSGFYNNDRA 280 ++ QA+ + +D L +R +G + + + Sbjct: 765 GRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSH---WVYGSPRLERYNGL 821 Query: 281 VLLVVNRQAGANIIETVAQIKAQLPALRAVLPASVSLNIAMDRSPVIKATLHEAEMTLLI 340 + + +A + A + L + LPA + + S + + ++A + I Sbjct: 822 PSMEIQGEAAPGT--SSGDAMALMENLASKLPAGIGYDW-TGMSYQERLSGNQAPALVAI 878 Query: 341 AVVLVVMVVFLFLGSFRASLIPTLAVPVSLVGTFAIMHLFGFSLNNLSLMALILATGLVV 400 + V+V + + S+ + L VP+ +VG LF + ++ L+ GL Sbjct: 879 SFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSA 938 Query: 401 DDAIVVLENI-SRHIHNGLDPMKAAFLGAKEVGFTLLSMNVSLVAVFISILFMGGLVESL 459 +AI+++E G ++A + + +L +++ + + + G Sbjct: 939 KNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGA 998 Query: 460 FREFSITLSVSIVVSLIVSLTLTPML 485 I + +V + ++++ P+ Sbjct: 999 QNAVGIGVMGGMVSATLLAIFFVPVF 1024 Score = 79.1 bits (195), Expect = 5e-17 Identities = 55/326 (16%), Positives = 119/326 (36%), Gaps = 14/326 (4%) Query: 707 QVTLVVNRDTAKRLGIDMNMVTAVLNNAYSQ----RQVSTIYDSLNQYKVVMEVNPKYAQ 762 + + ++ D + + V L Q + T Q + ++ + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF-K 241 Query: 763 DPVTLEQVQL-ITADGQRVPLSSIAHYERSLANDR--VSHDGQFAAENISFDLAEGASLD 819 +P +V L + +DG V L +A E N +G+ A + LA GA+ Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGK-PAAGLGIKLATGANAL 300 Query: 820 KATVAIERAIAAI--GLPSDIISKMAGTANAF--ASTQKGQPWMILGSLLAVYLVLGILY 875 AI+ +A + P + F S + + +L LV+ + Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVF-LVMYLFL 359 Query: 876 ESYIHPLTILSTLPSAGVGALLTIYVLGSEFSLISLLGLFLLIGLVKKNAIMMIDLALHL 935 ++ L +P +G + G + +++ G+ L IGL+ +AI++++ + Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 936 EREQGMTPEESIRSACLQRLRPILMTTMAAILGALPLLLSTAEGAEMRKPLGLTIIGGLI 995 E + P+E+ + Q ++ M +P+ + + +TI+ + Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 996 FSQVLTLYTTPVVYLYLDRLRHRFNK 1021 S ++ L TP + L + + Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHH 505
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 31.5 bits (71), Expect = 0.010 Identities = 11/43 (25%), Positives = 20/43 (46%), Gaps = 1/43 (2%) Query: 126 MAAMRMQPGIEYAPWRVVLSLLIAIAAAAAAIWIAFHLRQQRP 168 M +M + + PW +LS+ I A A ++ + H + P Sbjct: 3 MTSMTLDLPRRF-PWPTLLSVCIHGAVVAGLLYTSVHQVIELP 44
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 96.7 bits (240), Expect = 3e-26 Identities = 79/262 (30%), Positives = 114/262 (43%), Gaps = 31/262 (11%) Query: 3 KVLIITGGSRGIGAATARLAASQGYKICINYLSDHAAAEKTAGQVRALGAQAITLQADVS 62 K+ ITG ++GIG A AR ASQG I + EK ++A A ADV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHI-AAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 63 NEDEIMRLFARVDSDLGRVTHLVNNAGTLSQASRVEDMSEFRMLKMMMTNVVGPMLCSKH 122 + I + AR++ ++G + LVN AG L + +S+ N G S+ Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGL-IHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 123 ALLRMLPRHGGHGGSIVNVSSLAA---RLGSAGEYVDYAASKGALDTFTIGLSKEVAGEN 179 M+ R G SIV V S A R A YA+SK A FT L E+A N Sbjct: 127 VSKYMMDRRSG---SIVTVGSNPAGVPRTSMAA----YASSKAAAVMFTKCLGLELAEYN 179 Query: 180 IRVNAVRPGFIFTDIH--------------ALSGDPFRVSKLEGALPMGRGGTPEEVAEA 225 IR N V PG TD+ S + F+ +P+ + P ++A+A Sbjct: 180 IRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKT-----GIPLKKLAKPSDIADA 234 Query: 226 ILWLLSDNASYATGTFIDLAGG 247 +L+L+S A + T + + GG Sbjct: 235 VLFLVSGQAGHITMHNLCVDGG 256
>PERTACTIN#Pertactin signature. Length = 922 Score = 25.4 bits (55), Expect = 0.014 Identities = 15/51 (29%), Positives = 18/51 (35%) Query: 7 VNKEAATMTLPNPIEVPDPNIDEPALPEQDPPSTPPPNETPVGDPPANAPP 57 V +A P P P P P P+ P PP + PA PP Sbjct: 563 VGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPP 613
>PERTACTIN#Pertactin signature. Length = 922 Score = 76.3 bits (187), Expect = 3e-16 Identities = 122/504 (24%), Positives = 189/504 (37%), Gaps = 83/504 (16%) Query: 413 AGRLLLQSTLGDETSPSDKLVVSQGTIGGTTSMRVSNVDGLGALTQGNGIEVVQATQGAT 472 AG L + + + SDKLVV + G R+ + GN + +VQ +G+ Sbjct: 475 AGSGLFRMNVFADLGLSDKLVVMRDASG---QHRLWVRNSGSEPASGNTMLLVQTPRGSA 531 Query: 473 SEVTAFSLQNSLSAGAYDYYLFKGGATAGSENSWFLRSTVIAPPLPETPPPSEPVPVPVP 532 + T + + G Y Y L A W L P Sbjct: 532 ATFTLANKDGKVDIGTYRYRL-----AANGNGQWSLVGAKAPPA---------------- 570 Query: 533 VPVPVPEPIPTPLPEPAPEPAPSPSTPPEPTEPTVPPAQPPPTDPIPSPAQLPATTLPVA 592 P+P P P P+P P+P P P P P P QP P P PA + A Sbjct: 571 -----PKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQP-PAGRELSAAANA 624 Query: 593 AIGTPSLPEPIRGAAPVPLYRPEVANYAIVPPAAATLALTSLGTFHERQGDQSLLAQSGA 652 A+ T + A+TL +R G+ L +G Sbjct: 625 AVNTGGV------------------------GLASTLWYAESNALSKRLGELRLNPDAGG 660 Query: 653 APAGWARVFGSDFKQQWSGTVSPGLDASLKGYQIGHDVYAWSLDGQQILRIGLFVAQNRL 712 A W R F +QQ D + G+++G D +A ++ G + +G R Sbjct: 661 A---WGRGFAQ--RQQLDNRAGRRFDQKVAGFELGAD-HAVAVAGGR-WHLGGLAGYTRG 713 Query: 713 DGKVQGFAGGFHARHTGRIKLHGDSVGAYWTLSSPTASYVDALVMSTRLDG---YSRSDR 769 D G GG VG Y T + + Y+DA + ++RL+ + SD Sbjct: 714 DRGFTGDGGG---------HTDSVHVGGYATYIANSGFYLDATLRASRLENDFKVAGSDG 764 Query: 770 G-LRIDTQGHALSLSVEAGHPFVLTPRWVAEPQVQIIHQRIDLDDQH--DGISHVGFDSQ 826 ++ + H + +S+EAG F W EPQ ++ R+ +G+ V + Sbjct: 765 YAVKGKYRTHGVGVSLEAGRRFAHADGWFLEPQAELAVFRVGGGAYRAANGLR-VRDEGG 823 Query: 827 PYNTGRLGIRFKGRYALA-GMPIEPYLRANLWRNAGGHDTVTFDHTERI--KTAHRSTTG 883 GRLG+ R LA G ++PY++A++ + G TV T I +T R T Sbjct: 824 SSVLGRLGLEVGKRIELAGGRQVQPYIKASVLQEFDGAGTV---RTNGIAHRTELRGTRA 880 Query: 884 SLGAGMVIKVASDTSVYWGADYNR 907 LG GM + S+Y +Y++ Sbjct: 881 ELGLGMAAALGRGHSLYASYEYSK 904
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.7 bits (85), Expect = 1e-04 Identities = 31/154 (20%), Positives = 61/154 (39%), Gaps = 12/154 (7%) Query: 27 QIVSIVFYTFIAFLCIGLPIAVLPGYVHDQLGFSPLIA--GLAIASQYLATLLSRPFAGR 84 ++ I+ + + IGL + VLPG + D + + + A G+ +A L P G Sbjct: 6 PLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 85 ATDSLGSKRSIVFGLWGIGISGVMTLLATLLEDFATLSLSILIVARLFLGVSQGLIGVGT 144 +D G + ++ L G + + A L +L + R+ G++ G G Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMATAP--------FLWVLYIGRIVAGIT-GATGAVA 116 Query: 145 ISWCIGKVGAEHTARSISWNGIASYGAIAIGAPL 178 ++ + AR + A +G + P+ Sbjct: 117 GAYIADITDGDERARHFGFMS-ACFGFGMVAGPV 149
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 38.4 bits (89), Expect = 4e-05 Identities = 13/64 (20%), Positives = 19/64 (29%), Gaps = 2/64 (3%) Query: 340 APVEAPAAAPMPEPEPQVSEPAPAEQPEKQVPPQPPAPSAEPAQASAPGAPLSIPPGAAE 399 P + + P V EP P +P + P + P +P P E Sbjct: 51 TPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKP--KPKPKPKPKPVKKVQE 108 Query: 400 GPAE 403 P Sbjct: 109 QPKR 112 Score = 34.2 bits (78), Expect = 7e-04 Identities = 21/103 (20%), Positives = 30/103 (29%), Gaps = 17/103 (16%) Query: 312 DPAIESSVVSAAPLPSTANVSTGEPSSGAPVEAPAAAPMPEPEPQVSEPAPA-------- 363 I ++V+ A L V P P P P E V P Sbjct: 42 AQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPK 101 Query: 364 ------EQPEKQVPP---QPPAPSAEPAQASAPGAPLSIPPGA 397 EQP++ V P +P +P A A + + Sbjct: 102 PVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSK 144
>PF07520#Virulence protein SrfB Length = 1041 Score = 1292 bits (3344), Expect = 0.0 Identities = 369/1111 (33%), Positives = 542/1111 (48%), Gaps = 149/1111 (13%) Query: 2 LPELTQFEDTVHLINDSGIQFLDFAVKLDLRNEPAGRFAKMGNTLISRLLQNQETKQYFH 61 L L D + L+ SGIQ LDF ++ + + RF I R E + Sbjct: 9 LRRLVSLGDEITLVPYSGIQILDFGFDINALDIRSFRF-------IERPEGAAEGRHRTL 61 Query: 62 FGPVGTANQSGERLAQSQAQERLVSEVDDEDLTLGMQSSFKLLDGLWLPAPVFRFLP--- 118 + G A + LA + + D++ ++ ++ + W+P PV R Sbjct: 62 YPLTGEAERDAPILAATTPE--------DDEYSVRPLAALEPFLEKWVPIPVLRLKNQRG 113 Query: 119 ---PQRYDEGPTNWARVRLIELEQPDVD-GNTHRLTLAFDTRSMASATGMQYLAPTRDDI 174 + YD GP++WAR+R +EL QPD + G+THR+ +A DT Y+AP R D Sbjct: 114 AGGEELYDPGPSSWARLRTVELPQPDPETGHTHRVQIALDTALSDQDQSAHYVAPERADS 173 Query: 175 NAGSSFRLACHARQSRWFLD-------------QKWVQDWLAEIYREGNR-HRPSEDVEE 220 FRL WFL Q WV DWL E++ + R RP + E Sbjct: 174 EKPREFRLVSDPGAMSWFLQRLEADEDGNAVDLQLWVSDWLKEMFLDFKRAERPGRSISE 233 Query: 221 ELVEQ--RHIGHYLNLLSLMAKPI--PEQRSSEPARVVVPEIKLAANGADSIDPPIQVDL 276 E + H YL+ L ++ + + P+ R A V P + P++VDL Sbjct: 234 ENLPHMFEHWARYLSYLQVIQRAVAPPKMRF---ANTVAPRDAV---------APVEVDL 281 Query: 277 VLDVGNSRTCGILIENH-GQSGDGMKHNYILQIRDLVNPERVYSQPFESRVEFAQASFGK 335 VLD+GNSRTCGILIE G++ + ++ L+IRDL PE YS FESRVEFA FG Sbjct: 282 VLDIGNSRTCGILIERFPGETRVDLTRSFPLEIRDLSRPEFHYSGLFESRVEFADLRFGD 341 Query: 336 ENFSVQSGRHDAFQWPTIARVGVEAGRLSGRRRGTEGSTGLSSPKRYLWDENAYTHGWRF 395 E ++ +SGR +AF WP+ R+G EA RL GTE +GLSSPKRYLWD++A WRF Sbjct: 342 ERYASRSGRRNAFMWPSFVRMGPEAVRLVQAEEGTETLSGLSSPKRYLWDDDAVLQDWRF 401 Query: 396 NNSYVQTDSEPKATAAPFSH----------KITKLGQAFYKLKNEDDRLPAFSPQYSRSS 445 N + ++ P+ A H T++G K K PA P++SRSS Sbjct: 402 QNHH-DPNNLPRPVRAAMRHLNEAGDVLAQVKTEIGLNLRKPKKTTPLTPAIRPRFSRSS 460 Query: 446 LMTFMLAEVLTQALLQINSPAQRTRMGHTQRPRQLSSIILTVPPGMPQVERSLLNDRLLQ 505 L FMLAEV+ A++QIN PA R+R + PR+L+ +IL++P E++++ R+ Sbjct: 461 LFGFMLAEVIAHAMVQINDPASRSRRSQSDLPRRLNRVILSLPTATSVQEQAMIRSRVSG 520 Query: 506 ALALVWKCMGWHEGDLDPSKAKGLNSPVPAPRVPLPRIKVEWDEATCGQLVYLYTEIREN 565 AL LV + +G +G S + P + V+WDEA+C QLVYLY+E+ + Sbjct: 521 ALTLVKEMLGTKDG----------TSTIAVE--GKPELLVDWDEASCTQLVYLYSELTQK 568 Query: 566 FAGHAQEFFDTLARPDK--ANRE--HITLASIDIGGGTTDLVITDYSLERGAEQASGSNV 621 F G F D +P A E + LA ID+GGGTTDL++T Y RG + N Sbjct: 569 FDGRIDTFLDLKGQPRPDPAGGESPSLRLACIDVGGGTTDLMVTTY---RGED-----NR 620 Query: 622 SIIPEQRFRDSFKVAGDDILLDIIQRFVLPALEQALSDFGVVSPRSLL-SRLCGDESTSA 680 + PEQ FR+ F+VAGDD++ +I VLP L+ +++ G + GD Sbjct: 621 VLHPEQTFREGFRVAGDDLVHRVISAIVLPRLQDSIAQAGGQFVAERMRELFGGDIGGQE 680 Query: 681 QEAIL-RQQLNLQVFVPLGLRLLKDYETYDPE-------------LPSPVHDYRFADLLE 726 Q+ + R+Q +++V VPL +L E + +P+PV + + E Sbjct: 681 QQTVQRRRQFSIRVLVPLAEAILSACEDAEEADRIDIPVADVLGLVPTPVGEEGDEEGHE 740 Query: 727 KEA--ISDRIREYVAGGVRRIDGGRDGFELGQVVL---RIDLPAIHQAFLKGQINLSKIL 781 + ++D I +Y+ ++ G +G+ L +VL R DL AI + + K+L Sbjct: 741 DASPQVTDEILDYLEKPATQL--GAEGWRLADMVLSASREDLDAIAREVFQ------KVL 792 Query: 782 DALCEVVFQYPCDALLLTGRPSRLPGVQAYIRRKVPLPPGRIVSMNGYRTGGWYPFHR-- 839 +CEV+ CD +LLTGRPSRLP V+A + + +PP R++SM+ Y+TG WYPF Sbjct: 793 GNMCEVIDHLGCDVVLLTGRPSRLPAVRAIVEEMLVVPPHRLISMHRYKTGNWYPFRDPV 852 Query: 840 NGQIDDPKSTAAVGAMLCLLSEQRKVSNFYFSVGRLKPYSTMRHIGKLDENNLVIDHDML 899 + ++ DPKST AVG ML LSE R + NF + G + ST R +G++D N + + ML Sbjct: 853 SQRVGDPKSTVAVGGMLIALSENR-IPNFKVTTGAFQMKSTARFVGEMDTNGQIPEGRML 911 Query: 900 YRDV----IKSDAQGNEFLQLHEPQLDGPQLRVLGKTRLGYRQLNAERWVAAPLYLIELT 955 + D+ KS +++H P +G RQL ERW PLY ++ Sbjct: 912 FEDLDLDARKSAQDPTAIVRMHSP------------VYIGARQLPLERWTTTPLYRLDFA 959 Query: 956 ERGTRKLVGKPTKDGKEACLLLRFRVDGADADRG----DAEIIAETLVIDDNIESNTGES 1011 + P K L+R D +A+ AE + E +D E G Sbjct: 960 NDSIAGKIKLPVK-----VELVREDDDFDEAETSLEKLRAERVREVFRVDA-AEDAEGTM 1013 Query: 1012 FDRKDVKLQLYTMLSAEGGASNYWLDSGSVS 1042 DV L L+T+ G YWLD+G Sbjct: 1014 IKNDDVVLSLHTL----GFEDEYWLDTGVFR 1040
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 34.6 bits (79), Expect = 4e-04 Identities = 26/108 (24%), Positives = 33/108 (30%), Gaps = 23/108 (21%) Query: 126 PGAAQTTVSIAPAQPTVQPVPEPAPAPQPETIEQPLPEPIVEPVPPAPVPQAKNRTVLLL 185 P AQ A ++P P P+P +P PEPI EP APV K + Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPK----- 98 Query: 186 IIGLALLAIIAAGLWFWLKKPPAPEPTAAAAATTPADVASPPAAPAAP 233 KP DV + PA+P Sbjct: 99 ------------------PKPKPKPKPVKKVEQPKRDVKPVESRPASP 128
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 80.1 bits (197), Expect = 4e-20 Identities = 71/253 (28%), Positives = 115/253 (45%), Gaps = 25/253 (9%) Query: 7 KTALVTGASSGIGEAVVERLCAEGLQVHALARSADKLATLAQRTGCIA-----HAIDVTD 61 K A +TGA+ GIGEAV L ++G + A+ + +KL + A DV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 62 LAGLT-----VLFEAQRFDVVVNNAGVDRPGSLLKADAEGIDLLIDVNLRAVLQIARLSL 116 A + + E D++VN AGV RPG + E + VN V +R Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 117 PGMVERDCGHIINISSIAAAYNFGGNSTYHATKAAVSMLSRQLRIDAFGKRVRVTEICPG 176 M++R G I+ + S A + Y ++KAA M ++ L ++ +R + PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 177 RVATDIFAHVHGD---SEEVRKRFIEGYEL--PVAK-----DIADAIAYVIAAPIAVNIG 226 TD+ + D +E+V K +E ++ P+ K DIADA+ ++++ G Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSG----QAG 244 Query: 227 HMEITPTLQVPGG 239 H+ + L V GG Sbjct: 245 HITMH-NLCVDGG 256
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 26.7 bits (59), Expect = 0.029 Identities = 7/31 (22%), Positives = 13/31 (41%) Query: 105 VRSSQAGRVVRFLAAEHERVGYGQPLIELEE 135 ++ + V + E E V G L++L Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTA 129
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 28.8 bits (64), Expect = 0.033 Identities = 10/19 (52%), Positives = 13/19 (68%) Query: 116 KVAAKRAMREAGVPCVPGP 134 ++AA A+RE GV VPG Sbjct: 54 RIAAVHALREVGVRTVPGM 72
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.1 bits (73), Expect = 6e-04 Identities = 10/29 (34%), Positives = 15/29 (51%) Query: 116 VKAEIAGVVTDILVTNGEEVQAGQALFTL 144 +K +V +I+V GE V+ G L L Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKL 127
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 40.6 bits (95), Expect = 8e-06 Identities = 65/349 (18%), Positives = 116/349 (33%), Gaps = 27/349 (7%) Query: 28 ASFAGQMVTVYALGSLLAAIPLTIATQSWRRRTVLLLTIIGFLVFNSVTALSSDYWLTLV 87 + G ++ +YAL A L + + RR VLL+++ G V ++ A + W+ + Sbjct: 42 TAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYI 101 Query: 88 ARFFAGVSAG---LAWSLIAGYARRMVVPQLQGRALAIAMVGTPIALSLGVPLGTWLGGF 144 R AG++ +A + IA + RA + G+ G LGG Sbjct: 102 GRIVAGITGATGAVAGAYIAD------ITDGDERARHFGFMSA--CFGFGMVAGPVLGGL 153 Query: 145 MGW---RMAFGLMSAMTLLLIVWVLVKVPD--------YPGQSSSQRMALRQVFFTPGVR 193 MG F +A+ L + +P+ ++ + + R V Sbjct: 154 MGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVA 213 Query: 194 SVLGVVFTWMLAHNILYTYVAPFVSG--AGLASDVDWVLLTFGIA-ALAGIWVTGRLVDR 250 +++ V F L + F A+ + L FGI +LA +TG + R Sbjct: 214 ALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAAR 273 Query: 251 HLRKTVLASLATFAAVSVFLGVFSGSAPAVYLGVFIWGLTFGGAATLLQTALADSAGEGA 310 + L L F+ + + + G LQ L+ E Sbjct: 274 LGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLAS-GGIGMPALQAMLSRQVDEER 332 Query: 311 DVALS-MNVVVWNSAIAGGGLLGGVLLGHWGVGVFPWVLLVLSVLSLVI 358 L + + G LL + W + + L L+ Sbjct: 333 QGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGAALYLLC 381 Score = 32.1 bits (73), Expect = 0.004 Identities = 29/130 (22%), Positives = 49/130 (37%), Gaps = 5/130 (3%) Query: 208 ILYTYVAPFVSGAGLASDVDWVLLTFGIAALAGIWVTGRLVDRHLRKTVLASLATFAAVS 267 +L + V + + +L + + A V G L DR R+ VL AAV Sbjct: 27 VLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVD 86 Query: 268 VFLGVFSGSAPAVYLGVFIWGLTFGGAATLLQTALADSAGEGADVALSMNVVVWNSAIAG 327 + + +Y+G + G+T G + +AD + SA G Sbjct: 87 YAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARH----FGFMSACFG 141 Query: 328 GGLLGGVLLG 337 G++ G +LG Sbjct: 142 FGMVAGPVLG 151
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.4 bits (146), Expect = 1e-13 Identities = 29/176 (16%), Positives = 58/176 (32%), Gaps = 4/176 (2%) Query: 1 MAQMGRPRTFDRDVAITQ-AMHLFWEHGYDATSLSQLKANIGGGITAPSFYAAFGSKQAL 59 MA+ + + I A+ LF + G +TSL ++ G +T + Y F K L Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAG--VTRGAIYWHFKDKSDL 58 Query: 60 FTEVMER-YLTTHGRVTDSLFDTTLPPREAIELTLRRSAKMQCEPDHPKGCLVSLGLMSA 118 F+E+ E + P + L + + + + + Sbjct: 59 FSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCE 118 Query: 119 CSEESKAISAPLAQARNLNRAGLIACIDRAIASGELPATVIPETFAAVFDSFMLGL 174 E + + + + I + LPA ++ A + ++ GL Sbjct: 119 FVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL 174
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.4 bits (76), Expect = 2e-04 Identities = 12/84 (14%), Positives = 33/84 (39%), Gaps = 8/84 (9%) Query: 54 TCRQVYVASIDDHIVATASLDQD-----TVRSVFVDPAHQGRGMGRQLMATLETVAARNG 108 + ++ ++++ + + + + + V ++ +G+G L+ A N Sbjct: 63 EGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENH 122 Query: 109 VELLRVPS---SITAEGFYLSLGF 129 L + + +I+A FY F Sbjct: 123 FCGLMLETQDINISACHFYAKHHF 146
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 76.2 bits (187), Expect = 1e-18 Identities = 63/258 (24%), Positives = 106/258 (41%), Gaps = 16/258 (6%) Query: 4 QIALITGASRGLGRNMALHLAKRGVHIIGTYRSGVAQAHSLKQEIEAQGGKIALLPLYIT 63 +IA ITGA++G+G +A LA +G HI + + ++A+ P + Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAA-VDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 64 ETASYPAFSSAVTDTLKTEFARERFDFLVNNAGNGLFANFVDATEEQFASLVATHLRGPV 123 + A +T ++ E D LVN AG ++E++ + + + G Sbjct: 68 D----SAAIDEITARIEREM--GPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVF 121 Query: 124 FLTQKLLPLMED--GGRVLNVSSGFVRFTLPGYSLYAAVKAALEVLTRYMAVELGSRQIR 181 ++ + M D G ++ V S + YA+ KAA + T+ + +EL IR Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 182 VNAIAPGAIATDF-------GGGAVRDNKDVNAYVAQGIALGRVGLPADIGAAVAAILSD 234 N ++PG+ TD GA + K GI L ++ P+DI AV ++S Sbjct: 182 CNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSG 241 Query: 235 DMAWANGTTFDVSGGQLL 252 V GG L Sbjct: 242 QAGHITMHNLCVDGGATL 259
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 76.6 bits (188), Expect = 1e-19 Identities = 34/158 (21%), Positives = 64/158 (40%), Gaps = 6/158 (3%) Query: 9 RQHIIDVARSLMTNKGYTAVGLAEVLITAGVPKGSFYYYFKSKEEFGQALLEEYFSEYLG 68 RQHI+DVA L + +G ++ L E+ AGV +G+ Y++FK K + + E S Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 69 RVDALMA-RPGTGAERLLAYFMYWSETQGTDLPEGKCLVVKLGAEVCDLSEDMRCVLEVG 127 A PG L ++ + T E + L++++ C+ +M V + Sbjct: 73 LELEYQAKFPGDPLSVLREILIHV--LESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 128 TAK---IIQRISACVEMGVSDGSIHPEGDHQGFAESLY 162 RI ++ + + + + A + Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMR 168
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 33.0 bits (75), Expect = 8e-04 Identities = 18/94 (19%), Positives = 35/94 (37%), Gaps = 3/94 (3%) Query: 260 KGQAEQARSLFAGLLERNPGSSILQHALGMWLLNHGQAEFALLSLAKATELAPDNNDYRY 319 G+ E A +F L + S LG GQ + A+ S + + + + Sbjct: 49 SGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPF 108 Query: 320 DLAVALHSLNELEAAQKQL---TQIVQNQPANRK 350 A L EL A+ L +++ ++ ++ Sbjct: 109 HAAECLLQKGELAEAESGLFLAQELIADKTEFKE 142
>NEISSPPORIN#Neisseria sp. porin signature. Length = 348 Score = 27.6 bits (61), Expect = 0.030 Identities = 14/38 (36%), Positives = 19/38 (50%) Query: 79 AARNEWMKSIPGILELTHNHGTESDANASYHNGNSDPR 116 AA+ + K + +HN TE A A+Y GN PR Sbjct: 245 AAQQQDAKLYGAMSGNSHNSQTEVAATAAYRFGNVTPR 282
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.9 bits (197), Expect = 1e-19 Identities = 34/143 (23%), Positives = 60/143 (41%), Gaps = 2/143 (1%) Query: 2 TRILAIEDDAITAKEIVTELSSHGLEVDWVDNGRDGLARAVSGDYDLITLDRMLPEMDGL 61 IL +DDA + LS G +V N +GD DL+ D ++P+ + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 TIVTHLRAQGISTPILMISALSDVDERVRGLRAGGDDYLPKPFASDEMAARVEVLLRRSN 121 ++ ++ P+L++SA + ++ G DYLPKPF E+ + L + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL--AE 121 Query: 122 PVSAAKTVLQVADLELNLISREA 144 P + + + L+ R A Sbjct: 122 PKRRPSKLEDDSQDGMPLVGRSA 144
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.3 bits (102), Expect = 1e-06 Identities = 22/157 (14%), Positives = 48/157 (30%), Gaps = 5/157 (3%) Query: 73 LTGDIQARKVTEQSFRVSGKLVKRYVDVGDRVRAGQVLARLDPREQKTDLASANAEVAVR 132 + + ++ K +D + Q +A+ EQ+ A E+ V Sbjct: 212 KRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVY 271 Query: 133 ESRLHLAEQNYQRQQLLLPKGYTNLSEYQK-ARSGLDSARGDLAALRAQQANARDQVGYT 191 +S+L E + ++ L ++ L + A ++ + Sbjct: 272 KSQLEQIESEILSAKEEY---QLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQAS 328 Query: 192 ELFAVADG-VITARHAEEGQVVQAATPVFNLAHDGQR 227 + A V + EG VV A + + + Sbjct: 329 VIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDT 365 Score = 35.2 bits (81), Expect = 4e-04 Identities = 18/105 (17%), Positives = 38/105 (36%), Gaps = 10/105 (9%) Query: 90 SGKLVKR-YVDVGDRVRAGQVLARLDP---REQKTDLASANAEVAVRESRLHLAEQNYQR 145 +VK V G+ VR G VL +L S+ + + ++R + ++ + Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIEL 162 Query: 146 QQLLL-----PKGYTNLSEYQKARSGLDSARGDLAALRAQQANAR 185 +L + N+SE + R + + + Q+ Sbjct: 163 NKLPELKLPDEPYFQNVSEEEVLRL-TSLIKEQFSTWQNQKYQKE 206 Score = 32.5 bits (74), Expect = 0.003 Identities = 9/83 (10%), Positives = 27/83 (32%) Query: 111 ARLDPREQKTDLASANAEVAVRESRLHLAEQNYQRQQLLLPKGYTNLSEYQKARSGLDSA 170 L+ +++ + + A + E+ + + LL K + + A Sbjct: 205 KELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEA 264 Query: 171 RGDLAALRAQQANARDQVGYTEL 193 +L ++Q ++ + Sbjct: 265 VNELRVYKSQLEQIESEILSAKE 287
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.1 bits (86), Expect = 1e-04 Identities = 25/122 (20%), Positives = 43/122 (35%), Gaps = 19/122 (15%) Query: 84 GDRVRKGDLLATLDPSDQQNRLRARQAELSRARSAWQQLSDEQTRYQQLYTRGVGSRARL 143 G+ VRKGD+L L +A+ + +S+ Q EQTRYQ L ++ Sbjct: 115 GESVRKGDVLLKLTALGA-------EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPE 167 Query: 144 DQLNSDLRSQNALLDQASAAV------------QQAGDHLAYTRLTAEFDGLVTQWQTEV 191 +L + QN ++ Q+ L + AE ++ + Sbjct: 168 LKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYE 227 Query: 192 GQ 193 Sbjct: 228 NL 229
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 468 bits (1207), Expect = e-151 Identities = 237/1041 (22%), Positives = 438/1041 (42%), Gaps = 68/1041 (6%) Query: 12 LKHRTLVWYMMFVSLLMGSWSFLNLGREEDPSFAIKTMVIQARWPGATLPDTLQQVTDRL 71 ++ W + + ++ G+ + L L + P+ A + + A +PGA VT + Sbjct: 6 IRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVI 65 Query: 72 EKKLEEIDALDYVKSYTLASES-TIFVFLKSETRSADIPAAWYQVRKKISDVRSELPSGI 130 E+ + ID L Y+ S + ++ S TI + +S T D A QV+ K+ LP + Sbjct: 66 EQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGT---DPDIAQVQVQNKLQLATPLLPQEV 122 Query: 131 QGP-AFNDEFGDVFGSIYAFTADGLSFRQ--LRDYVE-QVRADIRSVPNLGKIELLGAQR 186 Q ++ + + F +D Q + DYV V+ + + +G ++L GAQ Sbjct: 123 QQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY 182 Query: 187 EV-IYLNFSIRKLAALGIDQRQVLQSLQAQNSVTPAGVMEAGPE------RIAVRASGQF 239 + I+L+ L + V+ L+ QN AG + P ++ A +F Sbjct: 183 AMRIWLDAD--LLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 240 SSEEDLEAINLRFGD--RFFRLSDLATIERRYADPPSSLFRFNGQPAIGLAVAMKQGGNI 297 + E+ + LR RL D+A +E + + + R NG+PA GL + + G N Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELG-GENYNVIARINGKPAAGLGIKLATGANA 299 Query: 298 QAFGTQLQQRIDDLTTELPLGIDVHLVSSQAEVVEKAIGGFTHALFEAILIVLVVSFISL 357 ++ ++ +L P G+ V V+ +I LFEAI++V +V ++ L Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 358 G-VRAGLVVACSIPLVLALVFVFMEYSGITMQRISLGALIIALGLLVDDAMITVEMMVTR 416 +RA L+ ++P+VL F + G ++ +++ +++A+GLLVDDA++ VE + Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 417 L-ESGDSLQQAATFAYTSTAFPMLTGTLVTVAGFVPIGLNSSSAGEYVFTMFAVIAVALL 475 + E ++A + + ++ +V A F+P+ S G I A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 476 LSWLVAVLFAPLIGVHILKASAQ--HAAPG-----------RWMRGFSRLLIKTLEQRWW 522 LS LVA++ P + +LK + H G + ++ + K L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 523 VIGITLLMFVGSLFAGKLLQNQFFPDSDRPEILVDIYMPQNGSIEGTRQTMDRFEATLKD 582 + I L+ G + L + F P+ D+ L I +P + E T++ +D+ Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 583 DPDVLRWSSYVGKGAVRFYLPLDQQLSNPFYGQLVIVSQGGAARDRL-IERLRQRFRDDY 641 + S + G Q N + + D E + R + + Sbjct: 600 NEKANVESVFTVNG-----FSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMEL 654 Query: 642 VGV-GGYVQPLNMGPPVGWPVQYRVSGPDIEQVRSQAMALAAILDAN-----------AN 689 + G+V P NM V +G D E + + A+ A A+ Sbjct: 655 GKIRDGFVIPFNMPAIVE---LGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPAS 711 Query: 690 IGQVIYDWNEPGKVLKIDIAQDKVRQFGLSSEDVAQILNSLVTGTTITQVRDSTYLVDLV 749 + V + E K+++ Q+K + G+S D+ Q +++ + GT + D + L Sbjct: 712 LVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLY 771 Query: 750 GRAESDERSSIQTLSNLQIPTPNGSTVPLLAFATLSYEQEQPLVWRRDRLPTITLKANVL 809 +A++ R + + L + + NG VP AF T + P + R + LP++ + Sbjct: 772 VQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSM----EIQ 827 Query: 810 GTLQPAALVKQLKPAVEAFSAGLPLRYSVATGGAVEASARSQGPILKVVPLMLLLVVSFL 869 G P +E ++ LP G S +V + ++V L Sbjct: 828 GEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCL 887 Query: 870 MIQLHSVKKLLLVVSVVPLGLIGVVAALLMSGYPLGFVAILGVLALIGIIIRNSVILVTQ 929 S + V+ VVPLG++GV+ A + ++G+L IG+ +N++++V Sbjct: 888 AALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEF 947 Query: 930 IDEFIAA-GESAWSAVVKATEHRCRPILLTAAAASLGMIPIA------REVFWGPMAIAM 982 + + G+ A + A R RPIL+T+ A LG++P+A + I + Sbjct: 948 AKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQN-AVGIGV 1006 Query: 983 IGGIAIATLLTLFFLPALYVV 1003 +GG+ ATLL +FF+P +VV Sbjct: 1007 MGGMVSATLLAIFFVPVFFVV 1027
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.5 bits (92), Expect = 2e-05 Identities = 65/368 (17%), Positives = 124/368 (33%), Gaps = 45/368 (12%) Query: 43 IAPDIGLSSTAASLIVSLTQIGYALGLFFLVPLGDLLENRRLMLVTTVVAVL-SLLGAAF 101 IA D + + + + + +++G L D L +RL+L ++ S++G Sbjct: 40 IANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVG 99 Query: 102 AEQPNLFLLVSLLVGFSSVSVQMLIPLA-AHLAPEESRGRVVGSIMGGLLLGILLARPIA 160 +L ++ + G + + L+ + A P+E+RG+ G I + +G + I Sbjct: 100 HSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIG 159 Query: 161 SLVADHFGWRAVFGSAAVVMIGISVVLATTMP-KRLPEH-------------------RA 200 ++A + W + + +I + ++ R+ H Sbjct: 160 GMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT 219 Query: 201 SYGQLLFSLWTLLRTQPVLRQRA--------------------FYQACMFATFSLFWTAV 240 SY + L V R +F T + F + V Sbjct: 220 SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMV 279 Query: 241 PLELSRNHGLSQTQI-ALFALIGAI-GAIAAPISGRLADAGYTRITSLGALLFGALSFLP 298 P + H LS +I ++ G + I I G L D + F ++SFL Sbjct: 280 PYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLT 339 Query: 299 GLIHPVYSVIGLSITGV-VLDFCVQTSMVLGQRTVYALDAASRSRLNALYMTSIFIGGAI 357 + ++I V VL T V+ +L +L + F+ Sbjct: 340 ASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGT 399 Query: 358 GSAVASPL 365 G A+ L Sbjct: 400 GIAIVGGL 407
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 29.8 bits (67), Expect = 0.007 Identities = 39/143 (27%), Positives = 58/143 (40%), Gaps = 24/143 (16%) Query: 1 MLKFFAALLFAVATMAQAQ---DNTLHTDLPLDYLAQANVET--PDRPLVIFIHGYGSNA 55 ++K + LL A A DN T LP++ Q N + PLVIF+ G G A Sbjct: 5 LIKILSVLLLCSTANAFADEFADNLGLTLLPVEPSTQVNAASSHTKPPLVIFLSGDGGWA 64 Query: 56 ADLFGLKEHLPAGFNYLSVQAPVELQADSYKWFTQKKGGTDYDGVTEDLKSSGKRLTDFI 115 L + + PV + S K++ ++K D K + I Sbjct: 65 ----TLDKAVGGILQQQGW--PV-VGWSSLKYYWKQK----------DPKDVTQDTLAII 107 Query: 116 TQATEKFRTQPGKVFLVGFSQGA 138 + +F TQ KV L+G+S GA Sbjct: 108 DKYQAEFGTQ--KVILIGYSFGA 128
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 409 bits (1052), Expect = e-142 Identities = 84/420 (20%), Positives = 170/420 (40%), Gaps = 10/420 (2%) Query: 1 MLAGAGSFFLWASLAPLDQGIAVQGTVVVSGKRKAVQSLDGGVVSKILVSEGQLVKEGEP 60 ++ F+ + L ++ G + SG+ K ++ ++ +V +I+V EG+ V++G+ Sbjct: 64 IMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDV 123 Query: 61 LFRLDQTQVQADVQSLGAQYRMAWASLARWQSERDNLDEVRFPAELIAAGQGQNPDPRLA 120 L +L +AD + A R+Q +++ + P +P Sbjct: 124 LLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPE------LKLPDEPYFQ 177 Query: 121 LVLEGQ----RQLFSSRRQALAREQSGLQASIEGAGLQLAGMRRARSDLLAQAESLRQQL 176 V E + L + ++ + +++ + + + + + +L Sbjct: 178 NVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRL 237 Query: 177 RNLEPLAQNGFIPGNRLLEFQRQLSQVQQSLAQNAGETGRIEQGIVESRLRLQQQREEYQ 236 + L I + +LE + + + L + +IE I+ ++ Q + ++ Sbjct: 238 DDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFK 297 Query: 237 KEVRSQWADAQVKALTLEQQLASAGFSLQHSAILAPADGIAVNMGVHTEGAVVRAGETLL 296 E+ + L +LA Q S I AP + VHTEG VV ETL+ Sbjct: 298 NEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLM 357 Query: 297 EIVPQGTRLEVEGRLPVQLIDKVASHLPVDILFTAFNQSRTPRVAGEVSLISADQMQDEK 356 IVP+ LEV + + I + I AF +R + G+V I+ D ++D++ Sbjct: 358 VIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQR 417 Query: 357 TGQPYYVLRTSVGDAALEKLNGLVIKPGMPAEMFVRTGERSLLNYLFKPLLDRAGSALTE 416 G + V+ + + + + GM ++TG RS+++YL PL + +L E Sbjct: 418 LGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLEESVTESLRE 477
>MPTASEINHBTR#Metalloprotease inhibitor signature. Length = 122 Score = 101 bits (253), Expect = 4e-31 Identities = 42/120 (35%), Positives = 58/120 (48%), Gaps = 3/120 (2%) Query: 5 YFVRIVPVAVVLLVGISGASMAMSLKLPNPAELSGQWRLSLQGKADDACELQLNTEAPQL 64 + I V VL V +MA S +P+ A+++GQ + +A L Sbjct: 4 FSHLIGCVWQVLFVSAGAQAMASSFVVPSTAQMAGQLGIE---ATGSGVCAGPAEQANAL 60 Query: 65 TGDVACAAKWLHEPPAGWFPTPDGLALTDNQGNRLIHLNRMDEQTYEARLPGGELLILGR 124 GDVACA +WL + P W PTPDG+ L + +G + HLNR E Y R P G + L R Sbjct: 61 AGDVACAEQWLGDKPVSWSPTPDGIWLMNAEGTGITHLNRQKEGEYTGRTPSGADVTLQR 120
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 388 bits (997), Expect = e-133 Identities = 236/477 (49%), Positives = 321/477 (67%), Gaps = 14/477 (2%) Query: 6 ENAAIQLSAATSTSFDQINTFAHEYDRGGNLTINGKPSYSVDQAANFILRDDAAWADRDG 65 ++A LSA TS++++ + F +DRG LT+NGK SYS+DQAA I R++ +W + Sbjct: 10 DDAQHALSANTSSAYNSVYDFLRYHDRGDGLTVNGKTSYSIDQAAAQITRENVSWNGTNV 69 Query: 66 NG-TINLTYTFLTAKPAGFNNALGTFSAFNAQQKAQAVLSMQSWADVAKVSFTQAASGGD 124 G + NLT+ FL + + + F FNA+Q QA LS+QSW+DVA ++FT+ Sbjct: 70 FGKSANLTFKFLQSV-SSIPSGDTGFVKFNAEQIEQAKLSLQSWSDVANLTFTEVTGNKS 128 Query: 125 GHMTFGNYSDGSNG-----GSAFAYLPSGGRTDGQSWYLISDSYRQNVSPDNGNYGRQTL 179 ++TFGNY+ ++G A+AY P + G SWY + S +P + YGRQT Sbjct: 129 ANITFGNYTRDASGNLDYGTQAYAYYPGNYQGAGSSWYNYNQSN--IRNPGSEEYGRQTF 186 Query: 180 THEIGHTLGLSHPGDYNAVDGNPTYKDATYAEDTRGYSVMSYWSESNTDQNFVKGGASSY 239 THEIGH LGL+HPG+YNA +G+P+Y DA YAED+ +S+MSYW E+ T ++ Y Sbjct: 187 THEIGHALGLAHPGEYNAGEGDPSYNDAVYAEDSYQFSIMSYWGENETGADYNG----HY 242 Query: 240 SSAPLLDDIAAVQQLYGANLSTRATDTVYGFNSTAGRDFYSATSASSKVVFSVWDGGGKD 299 AP++DDIAA+Q+LYGAN++TR D+VYGFNS RDFY+AT +S ++FSVWD GG D Sbjct: 243 GGAPMIDDIAAIQRLYGANMTTRTGDSVYGFNSNTDRDFYTATDSSKALIFSVWDAGGTD 302 Query: 300 TLDFSGFTQNQKINLNAASFSDVGGMVGNVSIAKGVVVENAIGGSGNDLLIGNAAANDLK 359 T DFSG++ NQ+INLN SFSDVGG+ GNVSIA GV +ENAIGGSGND+L+GN+A N L+ Sbjct: 303 TFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGNDILVGNSADNILQ 362 Query: 360 GGAGNDIIYGGGGADSLTGGAGADIFVFGASSDSNRAAQDTIRDFVSGQDKIDVSAISTL 419 GGAGND++YGG GAD+L GGAG D FV+G+ DS AA D I DF G DKID+SA Sbjct: 363 GGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDSTVAAYDWIADFQKGIDKIDLSAFRNE 422 Query: 420 SALQFVN-AFSGHAGEAILNYNQSSNLGSLAIDFTGQGAGDFLVGTVGQAFATDIVV 475 L FV F+G E +L ++ ++++ +L + G + DFLV VGQA +DI+V Sbjct: 423 GQLSFVQDQFTGKGQEVMLQWDAANSITNLWLHEAGHSSVDFLVRIVGQAAQSDIIV 479
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.9 bits (70), Expect = 0.010 Identities = 13/38 (34%), Positives = 19/38 (50%) Query: 284 LVGVSNFIWLPIGGMLSDRFGRKPLLVAMTLLTILSAY 321 L + F P+ G LSDRFGR+P+L+ + Sbjct: 51 LYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYA 88
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 38.8 bits (90), Expect = 4e-06 Identities = 16/78 (20%), Positives = 34/78 (43%), Gaps = 2/78 (2%) Query: 93 MDGEVVGFANFSQCHFRGRCSLGNVIIAPKARSKGVGRYMITRMMEIAFDKHEATELIAS 152 ++ +G ++ G + ++ +A R KGVG ++ + +E A + H L+ Sbjct: 72 LENNCIGRIKIRS-NWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENH-FCGLMLE 129 Query: 153 CYNHNVPGLLFYPRMGFR 170 + N+ FY + F Sbjct: 130 TQDINISACHFYAKHHFI 147
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.9 bits (80), Expect = 5e-05 Identities = 14/53 (26%), Positives = 22/53 (41%) Query: 80 VAVDPQQRGKGLGSALVKHAEQALAHLGCVKINLQIHTFNESVQAFYQTLGYT 132 +AV R KG+G+AL+ A + + L+ N S FY + Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 29.5 bits (66), Expect = 0.047 Identities = 19/76 (25%), Positives = 30/76 (39%), Gaps = 5/76 (6%) Query: 240 GERASLTLAYEYNDYISPFDRGTVFTGGHPADISYDKRLDEKWSNTVGISETATARFEYQ 299 G + + L Y D + + R GG + K +T G+S EY Sbjct: 97 GVQLTAKLGYPITDDLDIYTRL----GGMVWRADTKSNVYGKNHDT-GVSPVFAGGVEYA 151 Query: 300 LSDDWKTRLTYGWNND 315 ++ + TRL Y W N+ Sbjct: 152 ITPEIATRLEYQWTNN 167
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 75.0 bits (184), Expect = 6e-19 Identities = 28/169 (16%), Positives = 59/169 (34%), Gaps = 3/169 (1%) Query: 1 MKVRTEARREAIIDAAASVFLEMGYERASMNEVTKRMGGSKATIYSYFPSKEELFIAVVN 60 K + R+ I+D A +F + G S+ E+ K G ++ IY +F K +LF + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 RLATAHLADAVSELTTYNGADTNAELRTLFTRFGERMLMVLINDDNALAVYRMVVAESGH 120 + +++ + E D + LR + E + + + G Sbjct: 65 L-SESNIGELELEYQAKFPGDPLSVLREILIHVLESTV-TEERRRLLMEIIFHKCEFVGE 122 Query: 121 SAIGMMFYDSGPRECLQTVTALMTAAMQRGQLRE-TDPHIAALQLTSLL 168 A+ + E + + ++ L AA+ + + Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYI 171
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 41.2 bits (96), Expect = 1e-05 Identities = 17/74 (22%), Positives = 34/74 (45%), Gaps = 13/74 (17%) Query: 364 SARFTGKIKPTITGAHVFKVRADGAYKLWINDELVLEDEGAQVSFDLIPVIPRTVKTPTL 423 SA ++G IK + + F AD +W++D+ ++I + K L Sbjct: 91 SAIWSGFIKVKKSDEYTFATSADNHVTMWVDDQ------------EVINKASNSNKI-RL 137 Query: 424 KAGTEYNVRLEYRR 437 + G Y ++++Y+R Sbjct: 138 EKGRLYQIKIQYQR 151
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 87.8 bits (217), Expect = 1e-23 Identities = 34/200 (17%), Positives = 78/200 (39%), Gaps = 5/200 (2%) Query: 16 RRRIPKGDLRKVEIIQAAMIIFARDGYAGASLTNIAKVAGISQVGLLHHFPNKLALLQAV 75 R+ + + I+ A+ +F++ G + SL IAK AG+++ + HF +K L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 76 LEHRDTYVASRLQEADQD---GSLQGFMSFLKLVMSFSIEDAAVSQALMIINTESLSVTH 132 E ++ + E L L V+ ++ + + II + V Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 133 --PAHRWFSERFGIVHGHLQAHLNALIQAGEVRSDVDVRQISLEIAAMMDGMQIQWLRSP 190 + + ++ L I+A + +D+ R+ ++ + + G+ WL +P Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAP 182 Query: 191 GDVQIEQAFARFIERLARDL 210 +++ ++ L Sbjct: 183 QSFDLKKEARDYVAILLEMY 202
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.6 bits (160), Expect = 3e-13 Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 4/118 (3%) Query: 706 SGETILIVDDEPTVRMLLTDALGDLGYTLIEASDSLAGLKLLRSDVHIDLLITDVGLPGG 765 +G TIL+ DD+ +R +L AL GY + S++ + + + DL++TDV +P Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAG-DGDLVVTDVVMP-D 59 Query: 766 MNGRQMADAGREVRPHLKTLFITGYAE-NAAIGDEQLGPGMKVLTKPFAIDVLASRVQ 822 N + ++ RP L L ++ AI + G L KPF + L + Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKG-AYDYLPKPFDLTELIGIIG 116
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 78.9 bits (194), Expect = 2e-20 Identities = 33/162 (20%), Positives = 64/162 (39%), Gaps = 8/162 (4%) Query: 5 RERNKELILRAASEEFADKGFAASKTSDIAAKAGVPKPNVYYYFKSKENLYREVLESIIE 64 + ++ IL A F+ +G +++ +IA AGV + +Y++FK K +L+ E+ E Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 65 PILRAS------TPFNPQGVPAEVLSRYIRSKIEISRDLPFASKVFASEIMHGAPHLTPE 118 I P +P V E+L + S + R +F G + + Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 119 QIEQLNGQARHNIE-CIQAWIDKGLIAA-LDPHHLMFTIWAA 158 L ++ IE ++ I+ ++ A L + Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGY 170
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.0 bits (65), Expect = 0.048 Identities = 18/96 (18%), Positives = 37/96 (38%), Gaps = 7/96 (7%) Query: 46 LPPGFAVVWSGFFNFLGVMLSSGAVAFGIIALLPVELIL--QTGS-SAGFAMIFALLIAA 102 LP G W+G + + A A I+ + V L L S S +++ + + Sbjct: 850 LPAGIGYDWTGMSYQE-RLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGI 908 Query: 103 IIWNLGTWWLGLPASSSHTLIGSIIGVGIA--NALM 136 + L ++G + +G++ NA++ Sbjct: 909 VGVLLAATLFNQKNDVY-FMVGLLTTIGLSAKNAIL 943
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 117 bits (294), Expect = 4e-31 Identities = 69/422 (16%), Positives = 141/422 (33%), Gaps = 95/422 (22%) Query: 30 KPRSTRKRVVSSVIFGAVALAGVLLVLYAWQFPPFASPIESTENAQ----VKGQTTLIAP 85 P S R R+V+ I G + +A +L VL +E A G++ I P Sbjct: 51 TPVSRRPRLVAYFIMGFLVIAFILSVL---------GQVEIVATANGKLTHSGRSKEIKP 101 Query: 86 QLSGYVYEVPVQDFQFVKAGDLLVRLDDRIYRQRLDQALAQLAVQKASLA---------- 135 + V E+ V++ + V+ GD+L++L + + L + Sbjct: 102 IENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIE 161 Query: 136 ---------------------------NNLQQRRSA--------EATIGQRQAELQNSIA 160 + ++++ S E + +++AE +A Sbjct: 162 LNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLA 221 Query: 161 QSRKSAADLR-------RNQALVTDGSVSK--------------SELDVTRAADAQANAA 199 + + R +L+ +++K +EL V ++ Q + Sbjct: 222 RINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESE 281 Query: 200 VAEAKAVLLIAREDLQT-VIVNRGSLEASVANAQAAIELARIDLDNTRIVAPRDGQLGQI 258 + AK + + + ++ ++ + + I AP ++ Q+ Sbjct: 282 ILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQL 341 Query: 259 GVR-LGAYVNSGAQLMALVPEQR--WIVANMKETQMANVRLGQPVSFTVDALDGRE---M 312 V G V + LM +VPE + A ++ + + +GQ V+A + Sbjct: 342 KVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYL 401 Query: 313 HGHVQRISPSAGSEFSLLPADNATGNFVKISQRIPVRIVVDADQPMLEHLRPGMSVVVSI 372 G V+ I+ A D G + I + ++ + L GM+V I Sbjct: 402 VGKVKNINLDA-------IEDQRLGLVFNVIISIEENCLSTGNKNIP--LSSGMAVTAEI 452 Query: 373 DT 374 T Sbjct: 453 KT 454
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 310 bits (797), Expect = e-101 Identities = 119/364 (32%), Positives = 193/364 (53%), Gaps = 34/364 (9%) Query: 284 TRKPLKLHSVKPAQAPVAPRSLDLEAISLGDARIEKAVLQAQRLLEKDIPLLIHGETGVG 343 + L +P++ + D + A +++ RL++ D+ L+I GE+G G Sbjct: 115 IGRALAEPKRRPSKLEDDSQ--DGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTG 172 Query: 344 KEVFVKALHQAGSRASEPLIAVNCAAIPADLVEAELFGYERGAFTGANQKGSIGLIRKAD 403 KE+ +ALH G R + P +A+N AAIP DL+E+ELFG+E+GAFTGA + G +A+ Sbjct: 173 KELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRS-TGRFEQAE 231 Query: 404 KGTLFLDEVGDMPMPVQARLLRVLQERCVQPLGSSELYPVDIRLISATNRTLRDQVQTGH 463 GTLFLDE+GDMPM Q RLLRVLQ+ +G D+R+++ATN+ L+ + G Sbjct: 232 GGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGL 291 Query: 464 FRQDLYYRISGLNIELPPLRERT-DKHALIQRIWER-HRDAHQRAGFSREVLELFEHHPW 521 FR+DLYYR++ + + LPPLR+R D L++ ++ ++ F +E LEL + HPW Sbjct: 292 FREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPW 351 Query: 522 PGNIRQLNSVIQVALALADEQPISAEHLPEDFLLDVGMDEECRETAQARQSPYRQSSTQD 581 PGN+R+L ++++ AL + I+ E + + ++ + A++ Q+ ++ Sbjct: 352 PGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEEN 411 Query: 582 LSHQ-----------------------------LQAAGGNISLLAKQLGVSRNTLYKRLR 612 + L A GN A LG++RNTL K++R Sbjct: 412 MRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIR 471 Query: 613 EQRI 616 E + Sbjct: 472 ELGV 475
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 114 bits (286), Expect = 2e-29 Identities = 82/399 (20%), Positives = 151/399 (37%), Gaps = 20/399 (5%) Query: 19 IGLSLATFMQVLDTTIANVALPTIAGNLGVSSEQSTWVITSFAVSNAIALPLTGWLSRRF 78 I L + +F VL+ + NV+LP IA + + WV T+F ++ +I + G LS + Sbjct: 17 IWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQL 76 Query: 79 GEVKLFLWATILFVLASFLCGISQSMPELVGFRALQGMVAGPLYPMTQTLLIAVY-PPAK 137 G +L L+ I+ S + + S L+ +P +++A Y P Sbjct: 77 GIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKEN 136 Query: 138 RGMALALLAMVTVVAPIAGPILGGWITDSYSWPWIFFINIPIGLFAVLVVRSQMAKRPVS 197 RG A L+ + + GP +GG I W ++ I + I + V + + + Sbjct: 137 RGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM-ITIITVPFLMKLL--KKEV 193 Query: 198 TARQPLDYIGLLALIVGVGSLQVVLDKGNDLDWFESNFILFGSLISLVALTFFVIWEMTD 257 + D G++ + VG+ + + S I F + S+++ FV Sbjct: 194 RIKGHFDIKGIILMSVGIVFF---------MLFTTSYSISFLIV-SVLSFLIFVKHIRKV 243 Query: 258 KHPIVNLRLFAYRNFRIGTLVMIGGYSGFFGINLILPQWLQTQMGYTATWAGLAVAPIGI 317 P V+ L F IG L + G ++P ++ + G + G Sbjct: 244 TDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGT 303 Query: 318 LPVLMS-PFVGKYAHKFDLRLLAGLAFLAMGLSCFMRAGF--NTDVDFEHVAMVQLFMGI 374 + V++ G + + + + +S F+ A F T F + +V + G+ Sbjct: 304 MSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVS-FLTASFLLETTSWFMTIIIVFVLGGL 362 Query: 375 GVALFFMPTLSILLSDLPPDQIADGSGLATFLRTLGGSF 413 + T I+ S L + G L F L Sbjct: 363 SFTKTVIST--IVSSSLKQQEAGAGMSLLNFTSFLSEGT 399
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 86.0 bits (213), Expect = 2e-20 Identities = 56/414 (13%), Positives = 110/414 (26%), Gaps = 102/414 (24%) Query: 22 KRKLLLTGLAIIVVLCGLALWGWYHFYGQWSEETDDAYVNGNVV------EITPLVTGTV 75 R+ L I+ L + + A NG + EI P+ V Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSV------LGQVEIVATANGKLTHSGRSKEIKPIENSIV 107 Query: 76 ISIGADDGDLVHEGQVLLQFDPSDAAVSLQSAEANL------------------------ 111 I +G+ V +G VLL+ A +++L Sbjct: 108 KEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPE 167 Query: 112 --------------GKVVRQVRGLYSNVDGMKAQLAAQRTAVQTA--------------- 142 +V+R + + Q + + Sbjct: 168 LKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYE 227 Query: 143 ------QDNYSRRRSLAAGGAIS--------------QEELSHARDSLTSAQSALNNIQQ 182 + SL AI+ EL + L +S + + ++ Sbjct: 228 NLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKE 287 Query: 183 QLSTSVALVDDTVVSSHPDVKAAAAQLRQ----AFLANARSTLVAPVTGYVAKRSVQ-LG 237 + L + ++ L S + APV+ V + V G Sbjct: 288 EYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEG 347 Query: 238 QRIQPGTATMAVIPLDQ-LWIDANFKETQLGKMRIGQPVEISSDLYGSDV--KYSGTIDS 294 + M ++P D L + A + +G + +GQ I + + G + + Sbjct: 348 GVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKN 407 Query: 295 LGAGTGSAFALLPAQNATGNWIKIVQRVPVRVHINPEELAQHPLRIGLSTTVEV 348 + G ++ + + PL G++ T E+ Sbjct: 408 INLDA-------IEDQRLGLVFNVIISIE--ENCLSTGNKNIPLSSGMAVTAEI 452
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 29.0 bits (64), Expect = 0.041 Identities = 23/111 (20%), Positives = 46/111 (41%), Gaps = 4/111 (3%) Query: 243 VEKADRVKQAADMAYEVSLDTDVKAHRGMDLVGDSVIAVQTISQQMASVT--DSMTALKS 300 E + + +A D + D KA + +++ SQ S D+++ + Sbjct: 196 TEAKEALDKATDATVKAGTDAKAKAEKADNILTKFQGTANAASQNQVSQGEQDNLSNVAR 255 Query: 301 QALLIGSIVDTIGSIAAQT--NLLALNAAIEAARAGEHGRGFAVVADEVRK 349 +L+ ++ +G ++ N LAL A++ R E + A +E RK Sbjct: 256 LTMLMAMFIEIVGKNTEESLQNDLALFNALQEGRQAEMEKKSAEFQEETRK 306
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 80.3 bits (198), Expect = 1e-17 Identities = 38/129 (29%), Positives = 60/129 (46%), Gaps = 9/129 (6%) Query: 965 VLVVDDHIEHRKVISGMLEPLGFTVAQAENGMEAVRQVSLLHPDLILMDLSMPDMDGWAT 1024 +LV DD R V++ L G+ V N R ++ DL++ D+ MPD + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 1025 LRMIRRNARSNAPVIVLSANANAST---DDDIG-HDYLSKPVHLRDLLDRLKHHLNLNWQ 1080 L I++ AR + PV+V+SA T + G +DYL KP L +L+ + L Sbjct: 66 LPRIKK-ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL----A 120 Query: 1081 HRSRTASET 1089 R S+ Sbjct: 121 EPKRRPSKL 129
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.1 bits (239), Expect = 3e-25 Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 5/150 (3%) Query: 9 DKGVILIVDDTPDNLALLSDALDEAGYMVMVALDGTSALLRIQRRRPDLILLDAMMPGMD 68 IL+ DD +L+ AL AGY V + + + I DL++ D +MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 69 GFETCRQIKQQPDASNIPVLFMTALTDSEHVVEGFEAGAIDYVIKPIQCNEMIARVASHL 128 F+ +IK+ ++PVL M+A ++ E GA DY+ KP E+I + L Sbjct: 62 AFDLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 129 RTARTLQSARSTSQPPG---INDAAAYTHL 155 + S G + +AA + Sbjct: 120 AEPKRRPSKLEDDSQDGMPLVGRSAAMQEI 149
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 95.5 bits (237), Expect = 9e-26 Identities = 61/258 (23%), Positives = 110/258 (42%), Gaps = 31/258 (12%) Query: 5 KKLLLTGASRGIGHATVKHFNAAGWEVFTAS-RQNWVDDCPWAEGLL----NHIHLDLED 59 K +TGA++GIG A + + G + ++ + D+ D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 60 IDSVSASMAAIKDKLGGRLDALVNNAGVSPKTPEGGRMGVLES-DYSTWIKVFNVNLFST 118 ++ A I+ ++G +D LVN AGV R G++ S W F+VN Sbjct: 69 SAAIDEITARIEREMG-PIDILVNVAGVL-------RPGLIHSLSDEEWEATFSVNSTGV 120 Query: 119 ALLARGLFDELKAAK-GSIINVTSIAGSKVHPFAGV-AYATSKAALSALTREMAFDFGPH 176 +R + + + GSI+ V S P + AYA+SKAA T+ + + + Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGV--PRTSMAAYASSKAAAVMFTKCLGLELAEY 178 Query: 177 GVRVNAIAPGEIDTSI-------------LSPGTAEIVERLVPMHRLGKPEEVASLIYFL 223 +R N ++PG +T + + G+ E + +P+ +L KP ++A + FL Sbjct: 179 NIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFL 238 Query: 224 CTAGASYVNGAEIHVNGG 241 + A ++ + V+GG Sbjct: 239 VSGQAGHITMHNLCVDGG 256
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 92.7 bits (230), Expect = 2e-21 Identities = 57/250 (22%), Positives = 84/250 (33%), Gaps = 26/250 (10%) Query: 441 DQLTDSYRTATTSATDLLTDFNVSQ-----DRIDLANLGFTGLGSGKNGTLNISYNATLD 495 + T + ++ D Q + G S + + + Sbjct: 231 ENETGADYNGHYGGAPMIDDIAAIQRLYGANMTTRTGDSVYGFNSNTDRDF-YTATDSSK 289 Query: 496 RTYVKSLDVDASGNRFELGLTGNLKDTLNASHF------IFQRVTEGTAGGDTLTGTAGN 549 D + G + N + LN F + G +GN Sbjct: 290 ALIFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGN 349 Query: 550 DVINGNAGVDRIDGGAGADTINGGADADTLTGGAGADVFVYSSRLDSYRNYTAGGPKQSD 609 D++ GN+ + + GGAG D + GGA ADTL GGAG D FVY S DS D Sbjct: 350 DILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDSTVA-------AYD 402 Query: 610 TIVDFNVAEDRIDLSAIGLRGPGD-------GSANTLYLSLNGDGSKTYVKTNAVDTTGN 662 I DF D+IDLSA G G + L + S T + + + Sbjct: 403 WIADFQKGIDKIDLSAFRNEGQLSFVQDQFTGKGQEVMLQWDAANSITNLWLHEAGHSSV 462 Query: 663 RFEIALEGNL 672 F + + G Sbjct: 463 DFLVRIVGQA 472 Score = 86.2 bits (213), Expect = 3e-19 Identities = 50/149 (33%), Positives = 67/149 (44%), Gaps = 14/149 (9%) Query: 794 ITGTESAEALYGTEGNDTLLGLGGDDTLRGDTGADVLNGGAGRDALYGGADTDTFVYSTL 853 I + E G GND L+G D+ L+G G DVL GGAG D LYGGA DTFVY + Sbjct: 334 IAHGVTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSG 393 Query: 854 TDSYRDYDASGLTATDTIFDFTPGQDKIDVSALGFLGLGN-------GENHTLYMTLNEA 906 DS + A D I DF G DKID+SA G + G+ + + + A Sbjct: 394 QDST-------VAAYDWIADFQKGIDKIDLSAFRNEGQLSFVQDQFTGKGQEVMLQWDAA 446 Query: 907 GDKTYVKSATSDVEGNRFEIALSGNLINT 935 T + + F + + G + Sbjct: 447 NSITNLWLHEAGHSSVDFLVRIVGQAAQS 475 Score = 85.0 bits (210), Expect = 6e-19 Identities = 57/225 (25%), Positives = 93/225 (41%), Gaps = 28/225 (12%) Query: 319 NGSDNLIRGNLITGSDNSTYGVAERNED----GTDRNSIVGNTI-----------SHTSK 363 L N+ T + +S YG + TD + + ++ S S Sbjct: 252 AAIQRLYGANMTTRTGDSVYGFNSNTDRDFYTATDSSKALIFSVWDAGGTDTFDFSGYSN 311 Query: 364 GLTLVYGDGSFA--GDAFPLVTVLGTEANDVITGGAAHELIFGLAGKDTLNGGTGDDILV 421 + +GSF+ G V++ + GG+ ++++ G + + L GG G+D+L Sbjct: 312 NQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGNDILVGNSADNILQGGAGNDVLY 371 Query: 422 GGAGADKLNGGAGADTFRFDQLTDSYRTATTSATDLLTDFNVSQDRIDLANLGFTGLGS- 480 GGAGAD L GGAG DTF + DS +A D + DF D+IDL+ G S Sbjct: 372 GGAGADTLYGGAGRDTFVYGSGQDST----VAAYDWIADFQKGIDKIDLSAFRNEGQLSF 427 Query: 481 ------GKNGTLNISYNATLDRTYVKSLDVDASGNRFELGLTGNL 519 GK + + ++A T + + S F + + G Sbjct: 428 VQDQFTGKGQEVMLQWDAANSITNLWLHEAGHSSVDFLVRIVGQA 472 Score = 68.8 bits (168), Expect = 7e-14 Identities = 65/282 (23%), Positives = 102/282 (36%), Gaps = 33/282 (11%) Query: 1338 LKGGDGSDSYYVDDVADRVVETNSDAWVGGVDTVYSALASYTLGAHLENIA----ITRTD 1393 G+G SY A+ + + ++ G +T Y +++IA + + Sbjct: 202 YNAGEGDPSYNDAVYAEDSYQFSIMSYWGENETGADYNGHYGGAPMIDDIAAIQRLYGAN 261 Query: 1394 TANATGNALDN--------VLYAGAGD----NVMGGRDGNDTASYLFASAGVTVALNTSA 1441 TG+++ A + G DT + S + LN + Sbjct: 262 MTTRTGDSVYGFNSNTDRDFYTATDSSKALIFSVWDAGGTDTFDFSGYSNNQRINLNEGS 321 Query: 1442 Q-QATGGSGLDTL---KGTENLTGSQFADSLTGNKNANVLNGGAGNDTLSGGAGDDVLIG 1497 G G ++ EN G D L GN N+L GGAGND L GGAG D L G Sbjct: 322 FSDVGGLKGNVSIAHGVTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLYG 381 Query: 1498 SSGADTLIGGTGADRYVFNSIDEVGRDGLRDIINGFKVSEGDKLDFTGFDARPLTDTHDA 1557 +G DT + G+G D V D + D G + D F L+ D Sbjct: 382 GAGRDTFVYGSGQDSTVA------AYDWIADFQKGI--DKIDLSAFRNEGQ--LSFVQDQ 431 Query: 1558 FTFIGNSAFSANNTGELRFADGVLYGNVDDNTGADFEIQLTG 1599 FT G + + L+ + ++ DF +++ G Sbjct: 432 FTGKGQEVMLQWDAAN---SITNLWLHEAGHSSVDFLVRIVG 470 Score = 55.4 bits (133), Expect = 1e-09 Identities = 47/222 (21%), Positives = 77/222 (34%), Gaps = 17/222 (7%) Query: 1234 DDTLIGSAGNDILDGDQGADQMTGGDGNDIYV----VDNSLDTVTESNDS-PSQVDTVVS 1288 + T + + D T D + + DT S S +++ Sbjct: 261 NMTTRTGDSVYGFNSNTDRDFYTATDSSKALIFSVWDAGGTDTFDFSGYSNNQRINLNEG 320 Query: 1289 SVSWTLGANVENLLLTGVSAIDGTGNALKNVITGNSSDNVVDGGAGGDLLKGGDGSDSYY 1348 S S G + GV+ + G + +++ GNS+DN++ GGAG D+L GG G+D+ Y Sbjct: 321 SFSDVGGLKGNVSIAHGVTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLY 380 Query: 1349 VDDVADRVV-ETNSDAWVGGVDTVYSALASYTLGAHLENIAITRTDTANATGNALDNVLY 1407 D V + D+ V D + I + N + + Sbjct: 381 GGAGRDTFVYGSGQDSTVAAYDWIADFQKGID--------KIDLSAFRNEGQLSFVQDQF 432 Query: 1408 AGAGDNVMGGRDGNDTASYL---FASAGVTVALNTSAQQATG 1446 G G VM D ++ + L A L QA Sbjct: 433 TGKGQEVMLQWDAANSITNLWLHEAGHSSVDFLVRIVGQAAQ 474 Score = 50.4 bits (120), Expect = 5e-08 Identities = 21/52 (40%), Positives = 29/52 (55%) Query: 1228 IFGTSDDDTLIGSAGNDILDGDQGADQMTGGDGNDIYVVDNSLDTVTESNDS 1279 + G S D+ L G AGND+L G GAD + GG G D +V + D+ + D Sbjct: 352 LVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDSTVAAYDW 403
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 132 bits (332), Expect = 1e-39 Identities = 82/254 (32%), Positives = 124/254 (48%), Gaps = 11/254 (4%) Query: 4 KVAMITGAASGIGQALAVAFARQGVAVAGGYYPADPHDPDETRRLVEEAGGECLMLPLDV 63 K+A ITGAA GIG+A+A A QG +A Y + + + E E P DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE--AFPADV 66 Query: 64 TFTASVDDLAAAAIKAYGRIDYAVANAGLLRRAPLLQMTDERWNEMLDVDLTGVMRTFRS 123 +A++D++ A + G ID V AG+LR + ++DE W V+ TGV RS Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 124 AVRHM--GEGGALVAISSIAGGVYGWQDHSHYAAAKAGVPGLCRSLAVELAPKGIRCNAV 181 ++M G++V + S GV + YA++KA + L +ELA IRCN V Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGV-PRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 182 IPGLIETP--QSL----DSENSLGPEGLAQAAKAIPLGRVGRADEVAALVRFLCSDEASY 235 PG ET SL + + L IPL ++ + ++A V FL S +A + Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 236 LTGQSIVIDGGLTV 249 +T ++ +DGG T+ Sbjct: 246 ITMHNLCVDGGATL 259
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.3 bits (84), Expect = 2e-04 Identities = 35/160 (21%), Positives = 61/160 (38%), Gaps = 13/160 (8%) Query: 47 LPEIGRHFSWSEVEQAEIATWV---AVGTAVVALAIGPLVDRLGRRVGIIFTVSGSAICS 103 LP + R S A + A+ A +G L DR GRR ++ +++G+A+ Sbjct: 28 LPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDY 87 Query: 104 ALTAIGGSWGKSPLILIRSLGGLGYAEETVNATYLSEIYAASDDPRLARRRGFIYSLVQG 163 A+ A L + R + G+ A V Y+++I + AR GF+ + Sbjct: 88 AIMATAPFL--WVLYIGRIVAGITGATGAVAGAYIADITDGDER---ARHFGFMSACFGF 142 Query: 164 GWPVGALIAAGLTAVLLPIIGWQGCFVFAAIPAIVIAIMA 203 G G ++ L+ F AA + + Sbjct: 143 GMVAGPVLGG-----LMGGFSPHAPFFAAAALNGLNFLTG 177
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 30.9 bits (69), Expect = 0.011 Identities = 17/78 (21%), Positives = 27/78 (34%), Gaps = 3/78 (3%) Query: 36 ERARREAEASAARWKHGQPLSPFDGVPVAWKDLFDVAGCVTTAGATVRNN---LSPALLD 92 E R+ A A + P + A + L VA + + + L L Sbjct: 235 EEQARQQAAIRAANTYAMPANGSVVATAAGRGLIQVAQGAASLAQAISDAIAVLGRVLAS 294 Query: 93 APSVGLLARAGMVSLGKT 110 APSV + A + +T Sbjct: 295 APSVMAVGFASLTYSSRT 312
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 426 bits (1097), Expect = e-149 Identities = 171/478 (35%), Positives = 239/478 (50%), Gaps = 51/478 (10%) Query: 4 SVIVVDDEAPIRQAVEQWLTLSGFEVQVFARAEECLAQMPEHFPGVVLTDVRMPGMTGLQ 63 +++V DD+A IR + Q L+ +G++V++ + A + +V+TDV MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 LLTHLHALDRDLPVILLTGHGDVPMAVEAMREGAYDFLEKPFSPETLISNLRRALEKRQL 123 LL + DLPV++++ A++A +GAYD+L KPF LI + RAL + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK- 123 Query: 124 VLENRRLHEQADARTRLDATLLGVSPSLQTLRRQVLELSQLPVNVIIRGETGSGKELVAR 183 R + + ++ L+G S ++Q + R + L Q + ++I GE+G+GKELVAR Sbjct: 124 -----RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVAR 178 Query: 184 CLHDFGPRAGKPFVALNCAAIPEYLFEAELFGHESGAFTGAQGKRIGRLEYADGGTVFLD 243 LHD+G R PFVA+N AAIP L E+ELFGHE GAFTGAQ + GR E A+GGT+FLD Sbjct: 179 ALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLD 238 Query: 244 EIESMPLAQQVKLLRVLQDKCLERLGSNQSIKVDLRIIAATKPDLLEEARAGRFREDLAY 303 EI MP+ Q +LLRVLQ +G I+ D+RI+AAT DL + G FREDL Y Sbjct: 239 EIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYY 298 Query: 304 RLNVAELRLPALRDRLEDIAQLFSHFSRAAAERMGREAPALSAARLNQLLSHDWPGNVRE 363 RLNV LRLP LRDR EDI L HF AE+ G + L + +H WPGNVRE Sbjct: 299 RLNVVPLRLPPLRDRAEDIPDLVRHF-VQQAEKEGLDVKRFDQEALELMKAHPWPGNVRE 357 Query: 364 LANAAER-------QTLGLE-------------------------------------MTP 379 L N R + E Sbjct: 358 LENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFA 417 Query: 380 PQADTQLPGHSLAARQEAFEAQCLRASLTRHKGDIKAVLNELQLPRRTLNEKMQRHAL 437 D P E + A+LT +G+ + L L R TL +K++ + Sbjct: 418 SFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.3 bits (211), Expect = 2e-19 Identities = 26/120 (21%), Positives = 58/120 (48%), Gaps = 6/120 (5%) Query: 670 VLMVEDNQDIGTYTRPMLEQLGFQVLWVSSASDALQELSGNPENFHVVFSDIAMPGMSGL 729 +L+ +D+ I T L + G+ V S+A+ + ++ +V +D+ MP + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD--GDLVVTDVVMPDENAF 63 Query: 730 ELYAEIEARYPWMPVVLTTGYSTEFATLAQDETHR--FDLLQKPYSRDDLAAMLHKAVSR 787 +L I+ P +PV++ + +T A + + +D L KP+ +L ++ +A++ Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNT--FMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 118 bits (298), Expect = 2e-31 Identities = 75/354 (21%), Positives = 141/354 (39%), Gaps = 52/354 (14%) Query: 3 VGIDLGTTNSLVAVWRDGSSELVTNALGETLTPSVVGLDDDGQ------ILVGKAARERL 56 + IDLGT N+L+ V G +V N PSVV + D VG A++ L Sbjct: 13 LSIDLGTANTLIYVKGQG---IVLN------EPSVVAIRQDRAGSPKSVAAVGHDAKQML 63 Query: 57 QTHPEKTTALFKRYMGSAQEIRLGAGTYRPEELSSLVLKSLKADVERAYGEPVTEAVISV 116 P A+ G + + E++ +K + ++ P ++ V Sbjct: 64 GRTPGNIAAIRPMKDGVIADF------FVTEKMLQHFIKQVH---SNSFMRPSPRVLVCV 114 Query: 117 PAYFSDAQRKATRIAGELAGLKVEKLINEPTAAALAYGLHQKQGETSFLVFDLGGGTFDI 176 P + +R+A R + + AG + LI EP AAA+ GL + S +V D+GGGT ++ Sbjct: 115 PVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGS-MVVDIGGGTTEV 173 Query: 177 SILELFDGVMEVRASAGDNFLGGEDFDRLLVEHFLALHRDEQDFPAKELVTPSLRREAER 236 +++ L V + +GG+ FD ++ + + + AER Sbjct: 174 AVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNY---------GSLIG--EATAER 217 Query: 237 VRKALG------QDDRVDFVLRHAEREWRKT--ITQEQMSDLFAPLLARLRSPIERALRD 288 ++ +G + ++ R+ + + ++ + L + S + AL Sbjct: 218 IKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQ 277 Query: 289 AKIR-VADLNE--ILLVGGTTRMPLIRKLAAGMFGRFPAMTLNPDEVVAQGAAI 339 +D++E ++L GG + + +L G + +P VA+G Sbjct: 278 CPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGK 331
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 35.6 bits (82), Expect = 4e-04 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 7/82 (8%) Query: 82 IGGWLMGLYADYKGRKAALMASVLLMCFGSLIIALTPGYESIGVGAPILLVFARLLQGLS 141 IG + G +D G K L+ +++ CFGS+I + + S+ L+ AR +QG Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSL-------LIMARFIQGAG 116 Query: 142 VGGEYGTSATYLSEMATKERRG 163 ++ KE RG Sbjct: 117 AAAFPALVMVVVARYIPKENRG 138
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 143 bits (363), Expect = 6e-40 Identities = 99/427 (23%), Positives = 192/427 (44%), Gaps = 31/427 (7%) Query: 8 TSLTQTPPAIRSILFALMMAVLLSALDQTIVAVSMPAISAQF-KDIDLLAWVISAYMVSL 66 TS +Q+ IL L + S L++ ++ VS+P I+ F K WV +A+M++ Sbjct: 3 TSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTF 62 Query: 67 TVAVPIYGKLGDLYGRRKLMLFGLGLFTLASLFCGMAQSM-EQLVLARVLQGIGAGGMVS 125 ++ +YGKL D G ++L+LFG+ + S+ + S L++AR +QG GA + Sbjct: 63 SIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPA 122 Query: 126 VSQAIIADIVPPRERGRYQGYFSSMYAVASVAGPVLGGLMTEYLSWRWVFLINLPLGAAA 185 + ++A +P RG+ G S+ A+ GP +GG++ Y+ W +L+ +P+ Sbjct: 123 LVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPM---I 177 Query: 186 LIVAYRTLVGLPVPQ--RKPIIDYLGTVLMIIGLTALLLGITQIGQGHDLGNRDVQLLLG 243 I+ L+ L + K D G +LM +G+ +L T L Sbjct: 178 TIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISF----------LI 227 Query: 244 TALVALAVFVWYERRAPEPLLPMHLFANK---SAVLCWCTVFFTSFQAISLIVLMPLRYQ 300 ++++ +FV + R+ +P + L N VLC +F T + ++P + Sbjct: 228 VSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGT---VAGFVSMVPYMMK 284 Query: 301 TVTG-GGADSAALHLLPLAIGMPMGAYFSGRRTAQTGRYKPLILTGALLMPVAILGMAFT 359 V A+ ++ + P + + + Y G + G L + G + V+ L +F Sbjct: 285 DVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNI-GVTFLSVSFLTASFL 343 Query: 360 PPQSLVVMSLFMILTGIATGMQFPTSLVGT--QNAVQPRDMGVATSTTNLFRSLGGAMGV 417 + M++ ++ G+ F +++ T ++++ ++ G S N L G+ Sbjct: 344 LETTSWFMTIIIVFV--LGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGI 401 Query: 418 ALMSALL 424 A++ LL Sbjct: 402 AIVGGLL 408
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 152 bits (384), Expect = 2e-48 Identities = 82/209 (39%), Positives = 126/209 (60%) Query: 1 MVRRTKEEAQITRSQILEAAEQAFYERGVARTTLADIATLAGVTRGAIYWHFNNKADLVQ 60 M R+TK+EAQ TR IL+ A + F ++GV+ T+L +IA AGVTRGAIYWHF +K+DL Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 AMLDSLQEPLDEMAQASQSEDEEDPLGCMRNLLIHLFHELALDPKTRRINEILFHKCEFT 120 + + + + E+ Q++ DPL +R +LIH+ + + R + EI+FHKCEF Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 121 DEMCDFRRQRQDNAIQCHDRITLGLSNAVRQGQLPQELDTGRAAVALFSYVNGIIYQWLL 180 EM ++ +++ ++ +DRI L + + LP +L T RAA+ + Y++G++ WL Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 181 VPDSFSLPAEAEQLVDVCLDMLRFSPTLR 209 P SF L EA V + L+M PTLR Sbjct: 181 APQSFDLKKEARDYVAILLEMYLLCPTLR 209
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.0 bits (96), Expect = 7e-06 Identities = 25/110 (22%), Positives = 47/110 (42%), Gaps = 6/110 (5%) Query: 55 PGRTTAF-RVAEVRPQVNGIILKRLFTEGGDVKAGQQLYQIDPAIYEANANSAKATLQSA 113 G+ T R E++P N I+ + + EG V+ G L ++ EA+ +++L A Sbjct: 87 NGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQA 146 Query: 114 KSMSDRYKQLV-----NEQAVSRQEYDTALASTQEAQAALQTSQINLRFT 158 + RY+ L N+ + + + E + TS I +F+ Sbjct: 147 RLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFS 196
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1285 bits (3326), Expect = 0.0 Identities = 665/1034 (64%), Positives = 823/1034 (79%), Gaps = 4/1034 (0%) Query: 1 MSKFFIDRPIFAWVIALVIMLVGALSISSLPINQYPSIAPPAIAIQVTYPGASAQTVQDT 60 M+ FFI RPIFAWV+A+++M+ GAL+I LP+ QYP+IAPPA+++ YPGA AQTVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VVQVIEQQLNGIDNLRYVSSESNSDGSMTITATFNQGTNPDTAQVQVQNKLNLATPLLPQ 120 V QVIEQ +NGIDNL Y+SS S+S GS+TIT TF GT+PD AQVQVQNKL LATPLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGIRVTKAVKNFLMVIGLVSEDGSMGKEDLANYIVSNMQDPISRTSGVGDFQVFGS 180 EVQQQGI V K+ ++LMV G VS++ ++D+++Y+ SN++D +SR +GVGD Q+FG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWLDPAKLNNFQLTPVDVRDAITAQNVQVSSGQLGGLPSISGQQLNATIIGKTRL 240 QYAMRIWLD LN ++LTPVDV + + QN Q+++GQLGG P++ GQQLNA+II +TR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 QTAEQFGNIFLKVNTDGSQVRLKDVATVGLGAENYSTDSQFDGKPASGLAIKLATGANAL 300 + E+FG + L+VN+DGS VRLKDVA V LG ENY+ ++ +GKPA+GL IKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAKAIRATVSSLEPFFPPGMKVVYPYDTTPVVSESIKGVVHTLIEAIVLVFLVMYLFLQ 360 DTAKAI+A ++ L+PFFP GMKV+YPYDTTP V SI VV TL EAI+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATVITTLTVPVVLLGTFGILAGFGFTINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 N RAT+I T+ VPVVLLGTF ILA FG++INTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 EEEKLSPRDATIKSMTQIQGALVGIALVLSAVLLPMAFFGGSTGVIYKQFSITIVSAMAL 480 E+KL P++AT KSM+QIQGALVGIA+VLSAV +PMAFFGGSTG IY+QFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVVVALIFTPALCATMLKPIDEKTHGQPKRGFFGWFNRTFDRSVVSYERGVGNMLKHKWL 540 SV+VALI TPALCAT+LKP+ H + K GFFGWFN TFD SV Y VG +L Sbjct: 481 SVLVALILTPALCATLLKPV-SAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 541 SYLGYIVIVAGMVFMFMRIPAAFLPEEDQGVIFAQIQTPAGSSTERTQEVIDNMREYLLT 600 L Y +IVAGMV +F+R+P++FLPEEDQGV IQ PAG++ ERTQ+V+D + +Y L Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 601 KESGAVKSVFSVNGFNFAGRGQSSAIAFVMLKPWEERD-AENSVFKLAERAQGYFFSLRD 659 E V+SVF+VNGF+F+G+ Q++ +AFV LKPWEER+ ENS + RA+ +RD Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 660 AMVFAIVPPSVLELGNATGFDVYLQDQGGVGHAKLMEARNQFLGMAAQSKI-LAGVRPNG 718 V P+++ELG ATGFD L DQ G+GH L +ARNQ LGMAAQ L VRPNG Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 719 LNDEPQYQLLIDDERASALGITLSDINNTLSIALGGSYVNDFIDRGRVKKVYIQGDAGAR 778 L D Q++L +D E+A ALG++LSDIN T+S ALGG+YVNDFIDRGRVKK+Y+Q DA R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 779 MTPEDLKKWYVRNSAGEMVPFSAFASGKWTYGSPKLSRYNGVAAEEILGTPAPGYSSGDA 838 M PED+ K YVR++ GEMVPFSAF + W YGSP+L RYNG+ + EI G APG SSGDA Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 839 MAEVEALAKKLPQGIGISWTGLSYEERLSGSQAPALYALSLLVVFLCLAALYESWSIPIA 898 MA +E LA KLP GIG WTG+SY+ERLSG+QAPAL A+S +VVFLCLAALYESWSIP++ Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 899 VILVVPLGVIGALMATSLRGLSNDVFFQVGLLVTVGLAAKNAILIVEFAKELHE-QGKSL 957 V+LVVPLG++G L+A +L NDV+F VGLL T+GL+AKNAILIVEFAK+L E +GK + Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 958 TDAAIEACRMRLRPIIMTSMAFILGVVPLAISSGAGSGSQHSIGTGVIGGMITAVVLAIF 1017 +A + A RMRLRPI+MTS+AFILGV+PLAIS+GAGSG+Q+++G GV+GGM++A +LAIF Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1018 WVPLFFVSISGLFK 1031 +VP+FFV I FK Sbjct: 1020 FVPVFFVVIRRCFK 1033
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.1 bits (91), Expect = 3e-05 Identities = 70/391 (17%), Positives = 136/391 (34%), Gaps = 58/391 (14%) Query: 76 IGGWLFGRVADKHGRKNSMLISVTMMCAGSLIIACLPTYASIGAWAPALLLMARLLQGLS 135 IG ++G+++D+ G K +L + + C GS+I ++ S+ L+MAR +QG Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSL-------LIMARFIQGAG 116 Query: 136 VGG----EYGTTATYMSEVALRGQRGFYASFQYVT-----LIGGQLL------------- 173 A Y+ + G S + IGG + Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM 176 Query: 174 -AVLTVVILQQFLTTEELRDYGWRIPFVIGAAAAVIALLLRRTLNETT------------ 220 ++TV L + L E + I +I + ++ +L T + Sbjct: 177 ITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIF 236 Query: 221 TAESRQDKDAGSITALFKNHAAAFITVLGYTAGGSLI-FYTFTTYMQKYLVNTGGMEAKT 279 R+ D L KN + G G++ F + YM K + A+ Sbjct: 237 VKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDV--HQLSTAEI 294 Query: 280 ASYIMTGALFLYMCMQPFFGMLADRIGRRNSMLLFGALGTLCTVPILMTLKTTTNPFIAF 339 S I+ + G+L DR G + + ++ + L+TT+ F+ Sbjct: 295 GSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSW-FMTI 353 Query: 340 ALITLALAIVSFYTSISGLVKAEMFPPQVRA----------LGVGLAYAVANAMFGGSAE 389 ++ + + T IS +V + + + A L G A+ + S Sbjct: 354 IIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL--SIP 411 Query: 390 FVALKLKSAGMENSFYWYVTAMMAVAFLFSL 420 + +L ++ S Y Y ++ + + + Sbjct: 412 LLDQRLLPMEVDQSTYLYSNLLLLFSGIIVI 442
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.9 bits (67), Expect = 0.021 Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 12/85 (14%) Query: 246 AFL-FVDIFDNSGTLIGVAKRAGLMGKDGHMPKMGRALIAD---STAAMAGSLLGTSTTT 301 +FL D F + + ++R +G DG +L+A T A+ SL ST Sbjct: 322 SFLSIADKFKRANKIEEYSQRFKKLGYDGD------SLLAAFHKETGAIDASLTTISTVL 375 Query: 302 SYIESAAGVSAGGRTGLTAVVVAVL 326 + + ++G+SA T L V+ L Sbjct: 376 ASV--SSGISAAATTSLVGAPVSAL 398
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 29.5 bits (66), Expect = 0.022 Identities = 10/44 (22%), Positives = 27/44 (61%), Gaps = 3/44 (6%) Query: 242 AALSNLDDNGVDNVTLVRLSAEELTEALNEVRPFRRLQGIDLKS 285 AALSN + + + V++ ++++ + ++++PF + GI++ Sbjct: 248 AALSNANK---PSASPVKVLSDKIIQIYSDIKPFADIAGINVPD 288
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.0 bits (78), Expect = 0.001 Identities = 35/136 (25%), Positives = 55/136 (40%), Gaps = 10/136 (7%) Query: 60 LAQFIPMLLLLMP-AGDLIDRYNRKVILMISWGVQAVCGVILFAFSALKLHDLRLIYGAL 118 LA + M P G L DR+ R+ +L++S AV + A + L ++Y Sbjct: 49 LALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAV-DYAIMATA----PFLWVLYIGR 103 Query: 119 MLYGCARAFTGPALQSLLPQIVPRDQLASAIATNSVIMRCSTVGGPLIGGYLYWLGGAEL 178 ++ G A TG + + I D+ A S V GP++GG +GG Sbjct: 104 IVAGITGA-TGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGL---MGGFSP 159 Query: 179 TYSVCVAAFIAGILLL 194 AA + G+ L Sbjct: 160 HAPFFAAAALNGLNFL 175
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 28.3 bits (63), Expect = 0.016 Identities = 14/51 (27%), Positives = 24/51 (47%), Gaps = 1/51 (1%) Query: 13 LMRQWRDDDLPAFAAMCMDPQVMRYFPEPLSRLESAAMIGRLRGHFAELGF 63 ++RQ R+ DL FA + + P+ L A + L+ F ++GF Sbjct: 138 MLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELKTAF-QIGF 187
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.007 Identities = 13/37 (35%), Positives = 19/37 (51%) Query: 14 SHILRGLSFDVKVGEVTCLLGRNGVGKTTLLRVLMGL 50 H+ R + K L G G+GK+TL+ L+GL Sbjct: 583 GHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.4 bits (76), Expect = 2e-04 Identities = 13/63 (20%), Positives = 26/63 (41%), Gaps = 1/63 (1%) Query: 81 RHTVEHSVYVRADQRGKGLGPRLMAELIERARACDKHMMVAAIESGNAASIALHERLGFK 140 +E + V D R KG+G L+ + IE A+ ++ + N ++ + + F Sbjct: 89 YALIED-IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147 Query: 141 TTG 143 Sbjct: 148 IGA 150
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 29.5 bits (66), Expect = 0.004 Identities = 10/61 (16%), Positives = 21/61 (34%), Gaps = 4/61 (6%) Query: 90 RAEVQKLMVLPTARGRGLGRQLMDEVEQTAVKLKRGLLHLDTEAGSTAEAFYRSLAYHRV 149 A ++ + V R +G+G L+ + + A + L E + Y + Sbjct: 89 YALIEDIAVAKDYRKKGVGTALLHKAIEWA--KENHFCGLMLETQDINISACH--FYAKH 144 Query: 150 G 150 Sbjct: 145 H 145
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 1120 bits (2898), Expect = 0.0 Identities = 427/567 (75%), Positives = 488/567 (86%), Gaps = 2/567 (0%) Query: 2 KISRQAYADMFGPTVGDKVRLADTELWIEVEKDFTTYGEEVKFGGGKVIRDGMGQGQLL- 60 ++SR AYA+MFGPTVGDKVRLADTEL+IEVEKDFTT+GEEVKFGGGKVIRDGMGQ Q+ Sbjct: 4 RMSRAAYANMFGPTVGDKVRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQVTR 63 Query: 61 AADVVDTLITNALIIDHWGIVKADVGIKNGRIAAIGKAGNPDIQPDVTIAVGAATEVIAG 120 VDT+ITNALI+DHWGIVKAD+G+K+GRIAAIGKAGNPD+QP VTI VG TEVIAG Sbjct: 64 EGGAVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAG 123 Query: 121 EGMILTAGGVDTHIHFICPQQIEEALMSGVTTMIGGGTGPATGTNATTVTPGPWHMARML 180 EG I+TAGG+D+HIHFICPQQIEEALMSG+T M+GGGTGPA GT ATT TPGPWH+ARM+ Sbjct: 124 EGKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIARMI 183 Query: 181 QASDSFPMNIGFTGKGNVSLPGPLIEQVKAGAIGLKLHEDWGTTPAAIDNCLSVADEYDV 240 +A+D+FPMN+ F GKGN SLPG L+E V GA LKLHEDWGTTPAAID CLSVADEYDV Sbjct: 184 EAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADEYDV 243 Query: 241 QVAIHTDTLNESGFVETTLAAFKNRTIHTYHTEGAGGGHAPDIIKACGSPNVLPSSTNPT 300 QV IHTDTLNESGFVE T+AA K RTIH YHTEGAGGGHAPDII+ CG PNV+PSSTNPT Sbjct: 244 QVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSSTNPT 303 Query: 301 RPFTRNTIDEHLDMLMVCHHLDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMLSSDS 360 RP+T NT+ EHLDMLMVCHHL P+I ED+AFAESRIR+ETIAAEDILHD+GAFS++SSDS Sbjct: 304 RPYTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDIGAFSIISSDS 363 Query: 361 QAMGRVGEVIMRTWQTADKMKKQRGPLPQDGPGNDNFRAKRYIAKYTINPAITHGISHEV 420 QAMGRVGEV +RTWQTADKMK+QRG L ++ NDNFR KRYIAKYTINPAI HG+SHE+ Sbjct: 364 QAMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVKRYIAKYTINPAIAHGLSHEI 423 Query: 421 GSIEVGKWADLVLWRPAFFGVKPTLILKGGAIAASLMGDANASIPTPQPVHYRPMFASFG 480 GS+EVGK ADLVLW PAFFGVKP ++L GG IAA+ MGD NASIPTPQPVHYRPMF ++G Sbjct: 424 GSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFGAYG 483 Query: 481 SSLHATSLTFISQAAFDAGVPETLGLKKQIGVVKGCR-TVQKKDLIHNDYLPDIEVDPQT 539 S +S+TF+SQA+ DAG+ LG+ K++ V+ R + K +IHN P IEVDP+T Sbjct: 484 RSRTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEVDPET 543 Query: 540 YQVKADGVLLWCEPADVLPMAQRYFLF 566 Y+V+ADG LL CEPA VLPMAQRYFLF Sbjct: 544 YEVRADGELLTCEPATVLPMAQRYFLF 570
>PF06580#Sensor histidine kinase Length = 349 Score = 30.6 bits (69), Expect = 0.009 Identities = 24/112 (21%), Positives = 39/112 (34%), Gaps = 29/112 (25%) Query: 270 LLQNLIGNALQHG----AVSHEITVAVSGGQNAVELRVHNEGKPIAEDAIGTIFDPLVRS 325 L+Q L+ N ++HG +I + + V L V N G + Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALK------------- 305 Query: 326 IREESDTQSTSTSLGLGLFIVKEVVNAHSG---SITVTSTIGDGTTFTVVLP 374 +T S G GL V+E + G I ++ G V++P Sbjct: 306 --------NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 50.5 bits (121), Expect = 5e-09 Identities = 50/221 (22%), Positives = 93/221 (42%), Gaps = 43/221 (19%) Query: 11 GIDFGTSNSTVGWQRPGVESLIALEDDKITL--PSVVFFNIEERRPVYGRLALHEYLEGY 68 ID GT+N+ LI ++ I L PSVV + A+ G+ Sbjct: 14 SIDLGTANT-----------LIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAV-----GH 57 Query: 69 EGRLM--RSLKSLLGSKLIKHDTSVLGTAMPFKDLLALFIGELKKRAENTAGREFEQVVL 126 + + M R+ ++ + +K V+ + +L FI ++ + R +V++ Sbjct: 58 DAKQMLGRTPGNIAAIRPMKD--GVIADFFVTEKMLQHFIKQVHSNS---FMRPSPRVLV 112 Query: 127 GRPVHFVDDDAQADQEAEDTLAEVARKIGFKDVSFQFEPIAAAFDYESTIENEELVLIVD 186 PV + +A +E+ A+ G ++V EP+AAA + ++VD Sbjct: 113 CVPVGATQVERRAIRES-------AQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVD 165 Query: 187 IGGGTSDFSLVRLSPERRTHADREQDILATGGVHIGGTDFD 227 IGGGT++ +++ L+ ++ + V IGG FD Sbjct: 166 IGGGTTEVAVISLN-----------GVVYSSSVRIGGDRFD 195
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 71.0 bits (174), Expect = 2e-14 Identities = 25/112 (22%), Positives = 55/112 (49%), Gaps = 2/112 (1%) Query: 1868 VMVVDDSVTVRKVTSRLLERHGMHVLTAKDGIDAMSLLQEHTPDIMLLDIEMPRMDGFEV 1927 ++V DD +R V ++ L R G V + + D+++ D+ MP + F++ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 1928 ASQIRQDEQLKELPIIMITSRSGQKHRDRAMALGVNEYLSKPYQENVLLESI 1979 +I+ + +LP++++++++ +A G +YL KP+ L+ I Sbjct: 66 LPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 80.3 bits (198), Expect = 5e-21 Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%) Query: 2 ARILIVDDSPTEMYKLTGMLEKHGHEVLKAENGADGVALARQEKPDAVLMDIVMPGLNGF 61 A IL+ DD L L + G++V N A D V+ D+VMP N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 QATRQLTKDADTSNIPVIMITTKDQETDKVWGKRQGARDYLTKPVDEETLMKTLNAVLA 120 ++ K ++PV++++ ++ + +GA DYL KP D L+ + LA Sbjct: 64 DLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.1 bits (169), Expect = 7e-17 Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 2/117 (1%) Query: 6 SALKVMVIDDSKTIRRTAETLLKNAGCEVITAIDGFDALAKIADNHPRIIFVDIMMPRLD 65 + ++V DD IR L AG +V + IA ++ D++MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 66 GYQTCALIKNNRAFKSTPVIMLSSKDGLFDKAKGRIVGSDQFLTKPFSKEELLSAIK 122 + IK R PV+++S+++ K G+ +L KPF EL+ I Sbjct: 62 AFDLLPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>RTXTOXINC#Gram-negative bacterial RTX toxin-activating protein C signature. Length = 170 Score = 28.3 bits (63), Expect = 0.025 Identities = 11/28 (39%), Positives = 14/28 (50%) Query: 196 IMAQGYLPAIKDGDKRILMVDGEPVPYC 223 + A LPAI+ +L D PV YC Sbjct: 30 LFAINVLPAIQANQYVLLTRDDYPVAYC 57
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 64.2 bits (156), Expect = 4e-14 Identities = 39/251 (15%), Positives = 74/251 (29%), Gaps = 43/251 (17%) Query: 20 RLGFTMMIAALIHLAVILGVGFTYVKPEQISQTLEITLATFKSEEKPKQADFLAQDDQQG 79 R + +++ IH AV+ G+ +T V I L +P +A D + Sbjct: 13 RFPWPTLLSVCIHGAVVAGLLYTSV-------HQVIELPA---PAQPISVTMVAPADLE- 61 Query: 80 SGTLDKAETLKTTELAPYQ-DTKVNKVTPPPSSKPVVKQEAPKTAVATTAASPQKTVAKR 138 A V + P P P +EAP K + Sbjct: 62 ------------PPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVK 109 Query: 139 DEVKPEPTTKAAPTFDSSDLSNEIASLEAELSTEQQLYAKRPKIHRLNAASTMRDKGAWY 198 +P+ K + P + A+ K Sbjct: 110 KVEQPKRDVKPVES-----------------RPASPFENTAPARPTSSTATAATSKPVTS 152 Query: 199 KDDWRKKVERVGNLNYPEEARRKQIYGNLRLLVSINRDGSLYEVLVLESSGQPLLDQAAQ 258 + + R YP A+ +I G +++ + DG + V +L + + ++ + Sbjct: 153 VASGPRALSRN-QPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVK 211 Query: 259 RIVRLAAPFAP 269 +R + P Sbjct: 212 NAMR-RWRYEP 221
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 39.6 bits (92), Expect = 1e-05 Identities = 25/125 (20%), Positives = 39/125 (31%), Gaps = 1/125 (0%) Query: 361 VDEDAVPTGSPAQPPTVTTTAPPAGVPAGQAAAQTPRSSIPAPTPAAKPTPAPAPTQVAV 420 + +PAQP +VT AP A + QA P + P V + Sbjct: 36 SVHQVIELPAPAQPISVTMVAP-ADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVI 94 Query: 421 AKPAPAPAPAAKPAEKPAAAAAKPATGGNWYSSQAPGHYVVQILGTSSEATAQAYIAEQG 480 KP P P P KP +K + +S + +++ A + Sbjct: 95 EKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVA 154 Query: 481 GEYRY 485 R Sbjct: 155 SGPRA 159 Score = 30.3 bits (68), Expect = 0.014 Identities = 14/85 (16%), Positives = 25/85 (29%), Gaps = 1/85 (1%) Query: 350 GPLAEAAGSSDVDEDAVPTGSPAQPPTVTTTAPPAGVPAGQAAAQTPRSSIPAPTPAAKP 409 P E + ++A +P P V + + S +P P Sbjct: 75 EPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAP 134 Query: 410 T-PAPAPTQVAVAKPAPAPAPAAKP 433 P + A +KP + A + Sbjct: 135 ARPTSSTATAATSKPVTSVASGPRA 159
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.3 bits (60), Expect = 0.042 Identities = 8/19 (42%), Positives = 11/19 (57%) Query: 4 LILVGPMGAGKSTIGRLLA 22 ++L G G GKST+ L Sbjct: 599 VVLEGTGGIGKSTLINTLV 617
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 273 bits (700), Expect = 3e-84 Identities = 104/405 (25%), Positives = 175/405 (43%), Gaps = 40/405 (9%) Query: 344 VPWDQALDLVLKTKGLDKRKVGSVLLVAPADEIAARERQELESL--------KQIAELAP 395 + W A D+V L+K S L + + A ER + + IA + Sbjct: 199 LSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSRQRIIAMIKQ 258 Query: 396 LRRE--------LLQVNYAKAADIAKLFQSVTS--AESKAEERGS--------ITVDDRT 437 L R+ ++ + YAKA+D+ ++ ++S K + I +T Sbjct: 259 LDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKNIIIKAHGQT 318 Query: 438 NNIIAYQTQDRLDELRRIVSQLDIPVRQVMIEARIVEANVDYNKQLGVRWGGSTNTSRNG 497 N +I D +++L R+++QLDI QV++EA I E LG++W + Sbjct: 319 NALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKN--AGMT 376 Query: 498 KWTTYGLDDNGDEGGNTNANLTSNIPFVDLGAADATTGIGLGFVTNNTLLDLELSAMEKT 557 ++T GL + G N + A + GI GF N + L+A+ + Sbjct: 377 QFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGN--WAMLLTALSSS 434 Query: 558 GNGEIVSQPKVVTSDKETAKILKGTEIPYQESSSSG-----ATTVSFKEASLSLEVTPQI 612 +I++ P +VT D A G E+P S + TV K + L+V PQI Sbjct: 435 TKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVERKTVGIKLKVKPQI 494 Query: 613 TPDNRIIMEVKVTKDEPDY----LNAVLGVPPIKKNEVNAKVLISDGETIVIGGVFSNTQ 668 + +++E++ ++ LG VN VL+ GET+V+GG+ + Sbjct: 495 NEGDSVLLEIEQEVSSVADAASSTSSDLGAT-FNTRTVNNAVLVGSGETVVVGGLLDKSV 553 Query: 669 SKVVDKVPFLGDVPYLGRLFRRDVVSESKSELLVFLTPRIMNNQA 713 S DKVP LGD+P +G LFR SK L++F+ P ++ ++ Sbjct: 554 SDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRD 598 Score = 43.8 bits (103), Expect = 2e-06 Identities = 30/179 (16%), Positives = 69/179 (38%), Gaps = 10/179 (5%) Query: 304 SLNFQDIDVRSVLQLIADFTNLNLVASDTVQGGITLRLQN-VPWDQALDL---VLKTKGL 359 S +F+ D++ + ++ N ++ +V+G IT+R + + +Q VL G Sbjct: 31 SASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVLDVYGF 90 Query: 360 DKRKVG-SVLLVAPADEIAARERQELESLKQIAELAPLRRELLQVNYAKAADIAKLFQSV 418 + VL V + + A + S + ++ + A D+A L + + Sbjct: 91 AVINMNNGVLKVVRSKD-AKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLLRQL 149 Query: 419 TSAESKAEERGSITVDDRTNNIIAYQTQDRLDELRRIVSQLDIPVRQVMIEARIVEANV 477 GS+ + +N ++ + L IV ++D + ++ + A+ Sbjct: 150 NDNAG----VGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVPLSWASA 204
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 31.3 bits (71), Expect = 0.005 Identities = 48/205 (23%), Positives = 79/205 (38%), Gaps = 44/205 (21%) Query: 151 VEVREAALALAGLTARVVDVEAYALERSFGLLAAQLGNG---HDELTVAVVDIGATMTTL 207 VE R + G AR V + +E +AA +G G + VVDIG T + Sbjct: 121 VERRAIRESAQGAGAREV----FLIEEP---MAAAIGAGLPVSEATGSMVVDIGGGTTEV 173 Query: 208 SVLHHGRIIYTREQLFGGRQLTDEI----QRRYGLSMEE--AGLAKKQGG--LPDDYVSE 259 +V+ ++Y+ GG + + I +R YG + E A K + G P D V E Sbjct: 174 AVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVRE 233 Query: 260 VLDPFK------------------EALVQQVSRSLQFFFAAGQYNSVDH--------IML 293 + + EAL + ++ + A + + ++L Sbjct: 234 IEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVL 293 Query: 294 AGGTASISGLEHLIQRRIGTPTMVA 318 GG A + L+ L+ G P +VA Sbjct: 294 TGGGALLRNLDRLLMEETGIPVVVA 318
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 27.6 bits (61), Expect = 0.042 Identities = 20/89 (22%), Positives = 28/89 (31%), Gaps = 3/89 (3%) Query: 66 IAEANKTPPSPTAPVKPKYDFYTLLPESEVIVPNEAVPEKTPPPVAPTAPVSPEQAAKID 125 + A+ PP P PE P EA P P P + + Sbjct: 50 VTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQ 109 Query: 126 TARAQAALSGLTPPPAPPVATTKPAAVTT 154 R + + PA P T PA +T+ Sbjct: 110 PKR---DVKPVESRPASPFENTAPARLTS 135
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.012 Identities = 12/40 (30%), Positives = 20/40 (50%), Gaps = 3/40 (7%) Query: 44 RVEVTPKNILMIGPTGVGKTEIAR---RLAKLANAPFIKV 80 R+ T +++ G +G GK +AR K N PF+ + Sbjct: 155 RLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAI 194
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 63.1 bits (153), Expect = 2e-14 Identities = 34/146 (23%), Positives = 56/146 (38%), Gaps = 8/146 (5%) Query: 1 MKTRDRILECALTLFNQQGEPNVSTLEIANEMGISPGNLYYHFHGKEPLILGLFERFQTE 60 +TR IL+ AL LF+QQG + S EIA G++ G +Y+HF K L ++E ++ Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 61 LAPLL-----DPPSDARLEPEDYWMFLHLIVERLSHYRFLFQDL---SNLAGRLPKLARG 112 + L P D + + + R L + + G + + + Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 113 IRNLLNSIKKTLASLLARLKARGQLV 138 RNL + L L Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLP 155
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.5 bits (76), Expect = 8e-04 Identities = 24/133 (18%), Positives = 35/133 (26%), Gaps = 16/133 (12%) Query: 137 EKAKP---VASRAAPAKPAPKTTAKPL-VKAAAKTVAKTADKAAAKTAAAKPAVKKAAAK 192 E A+ APA P+ T K +KTV K A TA + K+A + Sbjct: 1016 EIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSN 1075 Query: 193 PVDAANKAATATASKAKAVAKPAAAKKPA------------ARKPAAKPAASSPAANSST 240 A + + K+ A + S + Sbjct: 1076 VKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQ 1135 Query: 241 PAATAPAATPETP 253 P A P Sbjct: 1136 SETVQPQAEPARE 1148
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 105 bits (262), Expect = 1e-31 Identities = 38/148 (25%), Positives = 61/148 (41%), Gaps = 7/148 (4%) Query: 1 MFGISFSELLLVGLVALLVLGPERLPGAARTAGLWIGRLKRSFNAIKQEVEREIGADEIR 60 MF I FSELLLV ++ L+VLGP+RLP A +T WI L+ ++ E+ +E+ E + Sbjct: 1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQ 60 Query: 61 RQLHNEHILSLEDEARKMFA-------QNQHPETAYEPVSPQPAPVQTDATDTGHNSLGP 113 L SL + ++ A + + +Y P+ A + Sbjct: 61 DSLKKVEKASLTNLTPELKASMDELRQAAESMKRSYVANDPEKASDEAHTIHNPVVKDNE 120 Query: 114 AEPAAPKTALSLEKTAKPADAGTPVPTP 141 A A + + + P P P Sbjct: 121 AAHEGVTPAAAQTQASSPEQKPETTPEP 148
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 35.4 bits (81), Expect = 8e-04 Identities = 39/261 (14%), Positives = 87/261 (33%), Gaps = 9/261 (3%) Query: 381 TEQTSAGVNSQKVETDQVATAMHEMTATVQEVARNAEEASEAAVAADQQARDGERVVKEA 440 +E T + K E+ V + T T + A+EA A Q + Sbjct: 1034 SETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQ--SGSE 1091 Query: 441 IAQIERLASAVGNSSEAMGALKQESEKIGSVLDVIKSVA-QQTNLLALNAAIEAARAGEA 499 + + + + E K E+EK V V V+ +Q + E AR + Sbjct: 1092 TKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDP 1151 Query: 500 GRGFAVVADEVRSLAQRTQKSTEEIEALIASLQSGTHQAATVMDSSRELSASSVELTRRA 559 V E +S T + + + ++++ ++ TV + + Sbjct: 1152 ----TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATT 1207 Query: 560 GGSLENITKTVSAIQSMNQQIAAAAEQQSATAEEINRSIINVRDVSEQT--SAASEETAA 617 ++ + + + + + AT +RS + + D++ + S+ A Sbjct: 1208 QPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAK 1267 Query: 618 SSVELARLGNHLQLLVSRFTV 638 + +G + +S+ + Sbjct: 1268 AQFVALNVGKAVSQHISQLEM 1288
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.040 Identities = 14/71 (19%), Positives = 24/71 (33%), Gaps = 9/71 (12%) Query: 124 AEIRSNRQSRNQIRQRLDQRSEQALQAVAQVEAEVLKSVSQEQDSSERMEEFTNISQLRQ 183 E+R + QI + E+ + E+L + Q D NI L Sbjct: 266 NELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTD---------NIGLLTL 316 Query: 184 QIQVARYQVQA 194 ++ + QA Sbjct: 317 ELAKNEERQQA 327
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 34.3 bits (78), Expect = 0.002 Identities = 26/145 (17%), Positives = 50/145 (34%), Gaps = 6/145 (4%) Query: 495 KDAGKATEMRAYLLREIPAEPGKEPALLVADKADEKKAAAKEAAAKEAAKPAVAKESAND 554 K+ ATE A A ++ + + KE E + A ++ Sbjct: 1053 KNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKA 1112 Query: 555 QVEIAK-ADAPK---PEAAKPEAGKADASKADAAKGDVAKADAAKADDVAKGKDGKDIQQ 610 +VE K + PK + K E + +A+ A+ + + + ++ D +Q Sbjct: 1113 KVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ--SQTNTTADTEQ 1170 Query: 611 PATEAAPTHPEPAKTLQVMTETWSY 635 PA E + +P + S Sbjct: 1171 PAKETSSNVEQPVTESTTVNTGNSV 1195
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.9 bits (67), Expect = 0.049 Identities = 23/105 (21%), Positives = 44/105 (41%), Gaps = 5/105 (4%) Query: 463 RINNKTNGITFRRWLFQANPKLTEMLVESL----GEDVLDNAETRLKELEPFAEKSSFRK 518 NGITFR W + + ++ +E + G + ++ + E + K+S+ Sbjct: 901 LSIGHKNGITFRNWFEKESGDISNHEIEQIFDKSGRIITPDSLKKALEYQQRNNKASYVY 960 Query: 519 QMADQRLHSKRALAAIIHERLGIAVNPAAMFDVQVKRIHEYKRQL 563 S+ L +I+E + ++ A FDV+ +R QL Sbjct: 961 GNDALAYGSQGDLNPLINE-ISKIISAAGSFDVKEERTAASLLQL 1004
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 32.3 bits (73), Expect = 0.007 Identities = 14/61 (22%), Positives = 18/61 (29%), Gaps = 15/61 (24%) Query: 77 APAFVPPAQDAAPLPVDAVILQAPTAGPELIWDLPDEPQTQPTQPPEPAAALPQPSPPAT 136 PA + P Q P P V EP+ +P P A + P Sbjct: 51 TPADLEPPQAVQPPPEPVV---------------EPEPEPEPIPEPPKEAPVVIEKPKPK 95 Query: 137 P 137 P Sbjct: 96 P 96 Score = 31.1 bits (70), Expect = 0.015 Identities = 13/44 (29%), Positives = 16/44 (36%), Gaps = 1/44 (2%) Query: 95 VILQAPTAGPELIWDLP-DEPQTQPTQPPEPAAALPQPSPPATP 137 + L AP + P D Q QPP P+P P P Sbjct: 36 IELPAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIP 79
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.022 Identities = 5/33 (15%), Positives = 12/33 (36%) Query: 417 LVATQSTDFKRLGLWAVLLLGVLFLGWMAFSTL 449 L+ T + RL + ++ V+ + Sbjct: 48 LIETPVSRRPRLVAYFIMGFLVIAFILSVLGQV 80
>BCTLIPOCALIN#Bacterial lipocalin signature. Length = 171 Score = 111 bits (279), Expect = 2e-33 Identities = 56/150 (37%), Positives = 82/150 (54%), Gaps = 10/150 (6%) Query: 33 VDGVDLKQYQGTWYEIARLPMFFQRKCAQSEALYTLKDDGNIAVTNRCRTIE-GKWEEAT 91 V +L Y G WYE+ARL F+R +Q A Y +++DG I+V NR + E G+W+EA Sbjct: 26 VSDFELNNYLGKWYEVARLDHSFERGLSQVTAEYRVRNDGGISVLNRGYSEEKGEWKEAE 85 Query: 92 GTASPQVPGKTDKLWVVFDNWFSRLLPGVAKGDYWILDVS-EGYRTAVVGNPDRKYLWLL 150 G A L V F F G Y + ++ E Y A V P+ +YLWLL Sbjct: 86 GKAYFVNGSTDGYLKVSFFGPFY--------GSYVVFELDRENYSYAFVSGPNTEYLWLL 137 Query: 151 SRTPTVSASVRENMLGKARQQGYDTSRLIW 180 SRTPTV + + + ++++G+DT+RLI+ Sbjct: 138 SRTPTVERGILDKFIEMSKERGFDTNRLIY 167
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 28.2 bits (62), Expect = 0.032 Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 1/43 (2%) Query: 145 LFSSNPRGQNQEGWQGERYGAYHDLETWRQLLTDAGFAELEHY 187 LF + P+ + GW+GE DLE R TD FAE E + Sbjct: 107 LFGAKPQTELPLGWKGEPLSGAPDLEGMRVAETDK-FAEGESH 148
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 497 bits (1280), Expect = e-161 Identities = 241/1051 (22%), Positives = 442/1051 (42%), Gaps = 68/1051 (6%) Query: 7 LSEWAIKHQSFVWYLMFVALLMGVFSYMKLGREEDPSFTIKTMIIQTRWPGATVDETLEQ 66 ++ + I+ F W L + ++ G + ++L + P+ + + +PGA + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 67 VTDRIEKKLEELDSLDYVKSYT-RPGESTVFVYLRDTTN-AKAIPEIWYQVRKKVDDIRG 124 VT IE+ + +D+L Y+ S + G T+ + + T+ A QV+ K+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQ----VQVQNKLQLATP 116 Query: 125 QFPQGLQGPS-FNDEFGDVYGSIYAFTADGFSMRQ--LRDYVEKVRAD-IREVPGLGKVE 180 PQ +Q ++ Y + F +D Q + DYV D + + G+G V+ Sbjct: 117 LLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQ 176 Query: 181 MIGQQDEVLYLNFSTRKLAALGIDQSQVVQSLQSQNAVTPAGVIEAGPE------RISVR 234 + G Q + + L + V+ L+ QN AG + P S+ Sbjct: 177 LFGAQYAMR-IWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASII 235 Query: 235 TSGQFASEKDLATVNLRINDRFY--RLSDIADITRGYTDPPKPLFRFNGKPAIGLSIAMQ 292 +F + ++ V LR+N RL D+A + G + + R NGKPA GL I + Sbjct: 236 AQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELG-GENYNVIARINGKPAAGLGIKLA 294 Query: 293 KGGNIQAFGKALHERMDATTAELPVGIGVHKVSDQAEVVNKAVGGFTSALFEAVIIVLLV 352 G N KA+ ++ P G+ V D V ++ LFEA+++V LV Sbjct: 295 TGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLV 354 Query: 353 SFVSLG-FRAGLVVACSIPLVLAMVFVFMEYSGITMQRISLGALIIALGLLVDDAMITVE 411 ++ L RA L+ ++P+VL F + G ++ +++ +++A+GLLVDDA++ VE Sbjct: 355 MYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVE 414 Query: 412 MMVTRLEMGETKEQAATY-AYTSTAFPMLTGTLVTVAGFVPIGLNNSSAGEYTFTLFAVI 470 + + + + AT + + ++ +V A F+P+ S G I Sbjct: 415 NVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITI 474 Query: 471 AVAMLVSWVVAVLFAPVIGVHILSANIKPKSEEPGRIGRAFNS-----------SMLWAM 519 AM +S +VA++ P + +L E G FN+ S+ + Sbjct: 475 VSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKIL 534 Query: 520 RHRWLAIGITVGLFAASLFSMQFVQNQFFPSSDRPEILVDLNLPQNASINETRKVVDRF- 578 + I + A + + + F P D+ L + LP A+ T+KV+D+ Sbjct: 535 GSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVT 594 Query: 579 EASLKDD-PDIERWSTYIGQGSVRFYLPLDQQLENPFYAQLVIVSKGLEER-------GA 630 + LK++ ++E T G Q +N A + K EER A Sbjct: 595 DYYLKNEKANVESVFTVNGFS-------FSGQAQNAGMAF--VSLKPWEERNGDENSAEA 645 Query: 631 LTARLQKRL---RDDFVGIGSYVQALEMGPPVGRPLQ-YRVSGESIDKVRQHAIELATLL 686 + R + L RD FV + +E+G G + +G D + Q +L + Sbjct: 646 VIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMA 705 Query: 687 DHNP-HVGEVIYDWNEPGKVLRIDINQDKARQLGLSSEDVAKLMNSVVSGSTVTQVRDDI 745 +P + V + E +++++Q+KA+ LG+S D+ + +++ + G+ V D Sbjct: 706 AQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRG 765 Query: 746 YLINVVGRAEDAERGTPETLQNLQIVTPTGTSIPLLAFATVGYELEQPLVWRRDRKPTIT 805 + + +A+ R PE + L + + G +P AF T + P + R + P++ Sbjct: 766 RVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSME 825 Query: 806 VKGSVRDEIQPTDLVNQLKPEIDKFAAGLPVGYKVATGGTVEESSKAQGPIASVAPLMLF 865 ++G P ++ A+ LP G G + + ++ + Sbjct: 826 IQGEA----APGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFV 881 Query: 866 LMATFLMIQLHSVQKMFLVASVAPLGLIGVVLALIPTGTPLGFVAILGVLALIGIIIRNS 925 ++ L S V V PLG++GV+LA ++G+L IG+ +N+ Sbjct: 882 VVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNA 941 Query: 926 VILVTQI-DAYEKSGYLPWDAVVEATEHRRRPILLTAAAASLGMIPIA------REVFWG 978 +++V D EK G +A + A R RPIL+T+ A LG++P+A Sbjct: 942 ILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQN- 1000 Query: 979 PMAYAMIGGIIIATLLTLLFLPALYVAWYRI 1009 + ++GG++ ATLL + F+P +V R Sbjct: 1001 AVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031 Score = 89.9 bits (223), Expect = 3e-20 Identities = 83/533 (15%), Positives = 180/533 (33%), Gaps = 57/533 (10%) Query: 518 AMRHRWLAIGITVGLFAASLFSMQFVQNQFFPSSDRPEILVDLNLP-QNASINETRKVVD 576 +R A + + L A ++ + +P+ P + V N P +A + V Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT-VTQ 63 Query: 577 RFEASLKDDPDIERW---STYIGQGSVRFYLPLDQQLENPFYAQLVIVSKGLEERGALTA 633 E ++ ++ S G ++ +P AQ+ + +K Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGT---DPDIAQVQVQNK--------LQ 112 Query: 634 RLQKRLRDDFVGIGSYVQALEMGPPVGRPLQYRVSGESIDKVRQHAIELATLLDHN---- 689 L + G V+ + V+G D +++ + N Sbjct: 113 LATPLLPQEVQQQGISVEKSSSSYLM-------VAGFVSDNPGTTQDDISDYVASNVKDT 165 Query: 690 ----PHVGEVIYDWNEPGKVLRIDINQDKARQLGLSSEDVAKLMNS----VVSGSTVTQV 741 VG+V + +RI ++ D + L+ DV + + +G Sbjct: 166 LSRLNGVGDVQLFGAQ--YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTP 223 Query: 742 RDDIYLINVVGRAEDAERGTPETLQNLQI-VTPTGTSIPLLAFATV--GYELEQPLVWRR 798 +N A+ PE + + V G+ + L A V G E + Sbjct: 224 ALPGQQLNASIIAQT-RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARIN 282 Query: 799 DRKPTITVKGSVRDEIQPTDLVNQLKPEIDKFAAGLPVGYKVA----TGGTVEES-SKAQ 853 KP + + D +K ++ + P G KV T V+ S + Sbjct: 283 G-KPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVV 341 Query: 854 GPIASVAPLMLFLMATFLMIQLHSVQKMFLVASVAPLGLIGVVLALIPTGTPLGFVAILG 913 + L+ +M FL +++ + P+ L+G L G + + + G Sbjct: 342 KTLFEAIMLVFLVMYLFL----QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFG 397 Query: 914 VLALIGIIIRNSVILVTQIDAYEKSGYL-PWDAVVEATEHRRRPILLTAAAASLGMIPIA 972 ++ IG+++ +++++V ++ L P +A ++ + ++ A S IP+A Sbjct: 398 MVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMA 457 Query: 973 -----REVFWGPMAYAMIGGIIIATLLTLLFLPALYVAWYRIKEPSDEQRQEA 1020 + + ++ + ++ L+ L+ PAL + + + Sbjct: 458 FFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGG 510
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 39.4 bits (92), Expect = 2e-05 Identities = 19/99 (19%), Positives = 32/99 (32%), Gaps = 7/99 (7%) Query: 64 GRIARRNVDVGSEVKKGDLLATLDPTDQQNNVRGRQGDLANVQAQWINAQANARRQQELF 123 + V G V+KGD+L L G + D Q+ + A+ R Q L Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTAL-------GAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 124 DRGVGAQAQLDVALTDLKTASSSLEQAKAAEQQARDQLS 162 + + + S E+ ++Q S Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFS 196
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 35.2 bits (81), Expect = 3e-04 Identities = 21/144 (14%), Positives = 47/144 (32%), Gaps = 30/144 (20%) Query: 55 DVQARVQTRLSFRVNGKIIQRN---------VDVGDRVTARQVLARLDPRDLQINVDSAA 105 ++ A +L+ K I+ V G+ V VL +L + + Sbjct: 81 EIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQ 140 Query: 106 ASVA---AEQARVSQASAAF------------------VRQQKLLPKGYTSRSEYDSAQA 144 +S+ EQ R S + V ++++L + ++ + Q Sbjct: 141 SSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQN 200 Query: 145 AVRGSESSLKAAQAQLANAREQLS 168 E +L +A+ +++ Sbjct: 201 QKYQKELNLDKKRAERLTVLARIN 224 Score = 31.3 bits (71), Expect = 0.005 Identities = 14/164 (8%), Positives = 51/164 (31%), Gaps = 9/164 (5%) Query: 47 AASVALTGDVQARVQTRLSFRVNGKIIQRNVDVGDRVTARQVLARLDPRDLQINVDSAAA 106 + + + ++ + +D + +Q +A+ + + A Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVN 266 Query: 107 SVAAEQARVSQASAAFVR---QQKLLPKGYTSRSEYDSAQAAVRGSESSLKAAQAQLANA 163 + ++++ Q + + + +L+ + + + Q + +LA Sbjct: 267 ELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDN-----IGLLTLELAKN 321 Query: 164 REQLSYTALVADAPGVITARQA-EVGQVVQATVPIFDLARDGER 206 E+ + + A + + G VV + + + + Sbjct: 322 EERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDT 365
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 32.5 bits (73), Expect = 0.001 Identities = 21/79 (26%), Positives = 30/79 (37%), Gaps = 7/79 (8%) Query: 114 LKTQLESLHARIKEQH--RQHVERLAQEAANRQAQEAAQRQAEEEARASRGGRGGS---- 167 + SL R+ + +E A A QA A+R+AEE+AR R + Sbjct: 193 FTEAISSLQIRMNTLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAANTYAM 252 Query: 168 PTRGRTGCAAGSHRGSVPA 186 P G A RG + Sbjct: 253 PANGSVVATAAG-RGLIQV 270
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 40.7 bits (95), Expect = 7e-07 Identities = 25/105 (23%), Positives = 45/105 (42%), Gaps = 7/105 (6%) Query: 2 RITAFMIAAALAPPVGAAEPFLVPIYTPTPVFPPELVKTRYAGKVRAQLWIKSDGQVREA 61 R T+ AA + PV + + P +P R G+V+ + + DG+V Sbjct: 136 RPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNV 195 Query: 62 RAIES-GHPQLAAVVEQALRQWRYKPWVGTVGAPPMTTITVPVIF 105 + + + V+ A+R+WRY+P P + I V ++F Sbjct: 196 QILSAKPANMFEREVKNAMRRWRYEP------GKPGSGIVVNILF 234
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.4 bits (66), Expect = 0.031 Identities = 33/171 (19%), Positives = 58/171 (33%), Gaps = 21/171 (12%) Query: 55 LIDEGYTRGQLGVAMSAIAIAYGLSKFLMGIISDRSNPRYFLPFGLLVSAGIMFIFGFAP 114 L+ G+ ++ A+ ++G +SDR R L L +A I AP Sbjct: 35 LVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAP 94 Query: 115 WATSSVTIMFVLLFINGWAQGMGWPPSGRTMVHWWSQKER-------GGVVSVWNVAHNV 167 + ++++ + G G +G + ER VA V Sbjct: 95 ----FLWVLYIGRIVAG-ITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPV 149 Query: 168 GGGLIGPLFLLGMGWTNDWHAAFYVPAAVALLVAVFAFATMRDTPQSVGLP 218 GGL+G HA F+ AA+ L + + ++ + P Sbjct: 150 LGGLMGGFSP---------HAPFFAAAALNGLNFLTGCFLLPESHKGERRP 191