>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 28.8 bits (64), Expect = 0.023 Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 18/120 (15%) Query: 157 IAEELGISRAQFD-----QFLRMMQGGAQFGGGYQQQSGGGNWQQAQRGPTLEDACNVLG 211 EEL R FD F+ + QQQ G G QQAQ T ++A Sbjct: 310 TLEEL---RDSFDGYINNAFVNQIHLNFVMPPQAQQQQGQGQQQQAQ--ATAQEAVAAAA 364 Query: 212 VKPTDDATTIKRAYRKLMS-EHHPDKLVAKGLPPEMMEMAKQKAQEIQ-QAYELIKQQKG 269 V+ + + I + Y+ L+ + H G+ M ++A Q+ ++ + Q KQQ+G Sbjct: 365 VRLLNGSDQIAQLYKDLVKLQRH------AGIRKAMEKLAAQQEEDAKNQGKGDCKQQQG 418
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 29.4 bits (66), Expect = 0.040 Identities = 19/103 (18%), Positives = 39/103 (37%), Gaps = 18/103 (17%) Query: 300 ILIADKQSVGERAVKGICGQVDGSVV------PGFIGLEAGQS-AFGDIYAWFGRVLGWP 352 + I++K+ + + + ++G + G I + + + G P Sbjct: 281 VRISEKEKIK---ITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSV---LGDTKLLP 334 Query: 353 L-EQLAAQHPELKAQINASQKQ----LLPALTEAWAKNPSLDH 390 E++ P L+ + S+ Q LL AL E +P L + Sbjct: 335 QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRY 377
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 227 bits (581), Expect = 5e-73 Identities = 94/405 (23%), Positives = 184/405 (45%), Gaps = 13/405 (3%) Query: 6 LWRWHGITGDGNAQDGMLWAESRTLLLMALQQQMVTPLSLKRIAINSAQ----------- 54 + + + G G A+S L+++ + PLS+ + + Sbjct: 3 QYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRK 62 Query: 55 WRGDKS--AEVIHQLATLLKAGLTLSEGLALLAEQHPSKQWQALLQSLAHDLEQGIAFSN 112 R S A + QLATL+ A + L E L +A+Q L+ ++ + +G + ++ Sbjct: 63 IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 113 ALLPWSEAFPPLYQAMIRTGELTGKLDECCFELARQQKSQRQLTDKVKSALRYPIIILAM 172 A+ + +F LY AM+ GE +G LD LA + ++Q+ +++ A+ YP ++ + Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182 Query: 173 AIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLADFSGEWGWLLVLFGFLLAIANK 232 AI VV +L V+P+ + LP T+ +M ++D +G ++L +A + Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFR 242 Query: 233 LLMRRPTWLIARQKLLLRIPIMGSLMRGQKLTQIFTILALTQSAGITFLQGVESVRETMR 292 +++R+ ++ + LL +P++G + RG + L++ ++ + LQ + + M Sbjct: 243 VMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMS 302 Query: 293 CPYWVQLLTQIQHDISNGHPIWLALKNAGEFSPLCLQLVRTGEASGSLDLMLDNLAHHHR 352 Y L+ + G + AL+ F P+ ++ +GE SG LD ML+ A + Sbjct: 303 NDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQD 362 Query: 353 DNTMALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHLGDAMS 397 + L EP L++ ++ +V+A+ PI L MS Sbjct: 363 REFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLMS 407
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 49.5 bits (118), Expect = 2e-10 Identities = 27/79 (34%), Positives = 43/79 (54%), Gaps = 1/79 (1%) Query: 1 MDKQRGFTLIELMVVIGIIAILSSIGIPAYQNYLRKAALTDMLQTFVPYRTAVELCALEH 60 DKQRGFTL+E+MVVI II +L+S+ +P KA + V A+++ L++ Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDN 63 Query: 61 GGLDTCD-GGSNGIPSPTT 78 T + G + + +PT Sbjct: 64 HHYPTTNQGLESLVEAPTL 82
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.1 bits (73), Expect = 0.006 Identities = 15/60 (25%), Positives = 29/60 (48%), Gaps = 2/60 (3%) Query: 119 EVTEILVKVGDKV-EAEQSLITVEGDKASMEVPAPFAGTVKEIKVN-VGDKVSTGSLIMV 176 E+ + L + D + L E + + + AP + V+++KV+ G V+T +MV Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358 Score = 32.1 bits (73), Expect = 0.007 Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 2/63 (3%) Query: 26 DKVEAEQSLITVEGDKASMEVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAP 85 + V +T G S E+ + IVKEI V G+ + G +++ + AD Sbjct: 81 EIVATANGKLTHSGR--SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 86 AQA 88 Q+ Sbjct: 139 TQS 141 Score = 31.3 bits (71), Expect = 0.013 Identities = 17/106 (16%), Positives = 38/106 (35%), Gaps = 4/106 (3%) Query: 230 DKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIMIFEVEGAAPAAAP 289 + VA +T G S E+ +VKE+ V G+ V+ G + + ++ A Sbjct: 81 EIVATANGKLTHSGR--SKEIKPIENSIVKEIIVKEGESVRKGDV--LLKLTALGAEADT 136 Query: 290 AKQEAAAPAPAAKAEAPAAKAEGKSEFAENDSYVHATPLIRRLARE 335 K +++ + + + + P + ++ E Sbjct: 137 LKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEE 182
>INTIMIN#Intimin signature. Length = 939 Score = 28.9 bits (64), Expect = 0.050 Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 9/84 (10%) Query: 316 RESLASGE---IAAVQSTLVANNTPLNSRVYTVRSGDTLSSIASRLGVSTKDLQQWNKLR 372 + S A+GE S L+ +N+ N YT+++G+T++ ++ ++ + NK Sbjct: 35 QNSFANGENYFKLGSDSKLLTHNSYQNRLFYTLKTGETVADLSKSQDINLSTIWSLNKHL 94 Query: 373 GS------KLKPGQSLTIGAQRLA 390 S K +PGQ + + ++L Sbjct: 95 YSSESEMMKAEPGQQIILPLKKLP 118
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 29.7 bits (66), Expect = 0.019 Identities = 19/69 (27%), Positives = 30/69 (43%) Query: 265 DIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYF 324 + EL + +L + QV G A F +D E L I+ A +IF+ Sbjct: 466 NQFLELEKTKQLRLDTDQVYGNIATYNFENGRVRVDTGSNWSEVLPQIQETTARIIFNGK 525 Query: 325 ALDLAEKKI 333 L+L E++I Sbjct: 526 DLNLVERRI 534
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 30.4 bits (68), Expect = 0.027 Identities = 31/101 (30%), Positives = 42/101 (41%), Gaps = 9/101 (8%) Query: 10 PVGNGGPVITT-----PPIAGESGGMSTGSAVTDVSGAAEEMAEQAAADLFGALPEPSGL 64 P + G VI T P +G GG G + ++ S A A+ + A L E + Sbjct: 13 PYDDKGQVIITLLNGTPDGSGSGGGGGKGGSKSESSAAIHATAKWSTAQLKKTQAEQAAR 72 Query: 65 VKAAVAAAQAAAAA---AGISDMAGAVQDAAASLAAGAPGA 102 KAA A AQA A A A + V +A A+ P A Sbjct: 73 AKAA-AEAQAKAKANRDALTQRLKDIVNEALRHNASRTPSA 112
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 38.4 bits (89), Expect = 2e-05 Identities = 29/118 (24%), Positives = 45/118 (38%), Gaps = 22/118 (18%) Query: 121 FERGSAQIMPFFKTLLVELAPVFDSLY---NKIIITGHTDAM---AYKNNIYNNWNLSGD 174 F A + P + L +L +L +++ G+TD + AY N LS Sbjct: 223 FNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAY------NQGLSER 276 Query: 175 RALSARRVLEEAGMPEDKVMQVS-----AMADQMLLDAKNPQS-----AGNRRIEIMV 222 RA S L G+P DK+ + + K + A +RR+EI V Sbjct: 277 RAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.0 bits (91), Expect = 3e-05 Identities = 71/347 (20%), Positives = 135/347 (38%), Gaps = 20/347 (5%) Query: 62 KFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLEPGTQLRWMAALAVVIAFCS 121 +F +P++ + F RR LL + V A M W+ + ++A + Sbjct: 56 QFACAPVLGALSDRF--GRRPVLLVSLAGAAVDYAIMAT----APFLWVLYIGRIVAGIT 109 Query: 122 ASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSGGLALWLADKWLGWQGMYWLMA 181 + V A+ D+ +ER + GM+ L + ++ A Sbjct: 110 GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG--FSPHAPFFAAA 167 Query: 182 AL-LIPCIIATLLAPEP--TDTIPVPKTLEQAVVAPLRDFFGRNNAWLILLLIVLYKLGD 238 AL + + L PE + P+ + + + A L+ + ++ +G Sbjct: 168 ALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQ 227 Query: 239 AFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGALYGGILMQRLSLFRALLIFGIL 298 A +L F +DA +G+ G+L ++ A+ G + RL RAL+ G++ Sbjct: 228 VPA-ALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALM-LGMI 285 Query: 299 QGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGTSAFVALLMTLCNKSFSATQFALLS 358 A GY LL+ + + V GG+G A A+L ++ L+ Sbjct: 286 --ADGTGYILLAFATRGWMAFPIMVLL--ASGGIGMPALQAMLSRQVDEERQGQLQGSLA 341 Query: 359 ALSAVGRVYVGPVAGWFVEAHGWSTF--YLFSVAAAVPGLILLLVCR 403 AL+++ + VGP+ + A +T+ + + AA+ L L + R Sbjct: 342 ALTSLTSI-VGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>PF06291#Lambda prophage Bor protein Length = 102 Score = 28.9 bits (64), Expect = 0.006 Identities = 12/37 (32%), Positives = 19/37 (51%) Query: 34 NMFKKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQ 70 N KK+LF ++ GCA+ T+ PT P++ Sbjct: 4 NKMKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKE 40
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 29.8 bits (67), Expect = 0.026 Identities = 31/137 (22%), Positives = 54/137 (39%), Gaps = 24/137 (17%) Query: 245 IWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEA 304 W+ L L+ G +A +LR R+ + + P++ G+I Sbjct: 228 PWMLLALLAGFMAFRVMLR------QEKRRVS-----FHRRLLHLPLI----GRIARGLN 272 Query: 305 LARWPQTDGSWLSPDSFIPLAQQTGLS-EPLTLLIIRSVFEDMGDCLRQHPQQHISINLE 363 AR+ +T + S +PL Q +S + ++ R D +R+ H + LE Sbjct: 273 TARYARTLSILNA--SAVPLLQAMRISGDVMSNDYARHRLSLATDAVREGVSLHKA--LE 328 Query: 364 STVLTSEKIPQLLREMI 380 T L P ++R MI Sbjct: 329 QTAL----FPPMMRHMI 341
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1361 bits (3523), Expect = 0.0 Identities = 798/1033 (77%), Positives = 910/1033 (88%), Gaps = 1/1033 (0%) Query: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISRFYPGADAKTVQDT 60 M NFFI RPIFAWV+AII+M+AG LAIL+LPVAQYPTIAPPAV++S YPGADA+TVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMTGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 VTQVIEQNM GIDNLMYMSS SDS G+V ITLTF+SGTD DIAQVQVQNKLQLA PLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS 180 EVQQQG+SVEKSSSS+LMV G ++ + TQ+DISDYVA+N+KD +SR +GVGDVQLFG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 QYAMRIW++ + LNK++LTPVDVI +K QN Q+AAGQLGGTP + GQQLNASIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL 300 + EEFGK+ L+VN DGS V L+DVA++ELGGENY++IA NG+PA+GLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 DTA AI+A+LA+++PFFP G+K++YPYDTTPFV++SIHEVVKTL EAI+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTFA+LAAFG+SINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480 E+ LPPKEAT KSM QIQGALVGIAMVLSAVF+PMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWLNRMFEKSTHHYTDSVGGILRSTGR 540 SVLVALILTPALCAT+LKP++ H E K GFFGW N F+ S +HYT+SVG IL STGR Sbjct: 481 SVLVALILTPALCATLLKPVSAE-HHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 541 YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT 600 YL++Y +IV GM LF+RLPSSFLP+EDQGVF+TM+QLPAGATQERTQKVL++VT YYL Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 601 KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD 660 EK NVESVF VNGF F+G+ QN G+AFVSLK W +R G+EN EA+ RA +I+D Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720 V FN+PAIVELGTATGFDFELIDQAGLGH+ LTQARNQLL AA+HP L SVRPNG Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 LEDT QFK+++DQEKAQALGVS++DIN T+ A GG+YVNDFIDRGRVKK+YV ++AK+R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 781 MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA 840 MLP+D+ YVR+A+G+MVPFSAF++S W YGSPRLERYNGLPSMEI G+AAPG S+G+A Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 841 MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSTPFS 900 M LME LASKLP G+GYDWTGMSYQERLSGNQAP+L AIS +VVFLCLAALYESWS P S Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 901 VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960 VMLVVPLG++G LLAAT NDVYF VGLLTTIGLSAKNAILIVEFAKDLM+KEGKG+ Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIF 1020 +EATL AVRMRLRPILMTSLAFILGV+PL IS GAGSGAQNAVG GVMGGMV+AT+LAIF Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1021 FVPVFFVVVRRRF 1033 FVPVFFVV+RR F Sbjct: 1020 FVPVFFVVIRRCF 1032
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 45.2 bits (107), Expect = 3e-07 Identities = 33/212 (15%), Positives = 72/212 (33%), Gaps = 23/212 (10%) Query: 100 TYQATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQGYDQALADAQQANAAVTA 159 + Y A +L + + Q+ Q +++ ++ L +Q + Sbjct: 256 EQENKYVEAVNELR--VYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGL 313 Query: 160 AKAAVETARINLAYTKVTSPISGRIGKSNV-TEGALVQNGQATVLATVQQLDPIYVDVTQ 218 + + + +P+S ++ + V TEG +V + T++ V + D + V Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE-TLMVIVPEDDTLEVTALV 372 Query: 219 SSNDFLRLKQELA----------NGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVD 268 + D + KV I D I+ + G + ++++ Sbjct: 373 QNKDIGFINVGQNAIIKVEAFPYTRYGYLV---GKVKNINLDAIEDQRLGLVFNVIISIE 429 Query: 269 QTTGSITLRAIFPNPDHTLLPGMFVRARLEEG 300 + S + I L GM V A ++ G Sbjct: 430 ENCLSTGNKNIP------LSSGMAVTAEIKTG 455 Score = 32.9 bits (75), Expect = 0.002 Identities = 26/127 (20%), Positives = 50/127 (39%), Gaps = 10/127 (7%) Query: 49 PLQITTELPGR-TSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQATYDS 107 ++I G+ T + R E++P + I+ + KEG + G L ++ +A Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA---- 134 Query: 108 AKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQGYDQALADAQQANAAVTAAKAAVETA 167 D K Q++ A+L RYQ L + I + + V+ + T+ Sbjct: 135 ---DTLKTQSSLLQARLEQTRYQILSRS--IELNKLPELKLPDEPYFQNVSEEEVLRLTS 189 Query: 168 RINLAYT 174 I ++ Sbjct: 190 LIKEQFS 196
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 222 bits (567), Expect = 5e-76 Identities = 215/215 (100%), Positives = 215/215 (100%) Query: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE Sbjct: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.017 Identities = 19/125 (15%), Positives = 40/125 (32%), Gaps = 6/125 (4%) Query: 28 QNTAFARASSNGDLPTKADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRIKEE 87 N RA L + + L L+ + A L++ ++ E Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSR--LDDFSSLLHKQAIAKHAVLEQENKYVEA 264 Query: 88 TVQLRQKVAEAPEKMRQATAALTALSDVDND--EETRKIL--STLSLRQLETRVAQALDD 143 +LR ++ + + +A V E L +T ++ L +A+ + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEER 324 Query: 144 LQNAQ 148 Q + Sbjct: 325 QQASV 329
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 38.9 bits (90), Expect = 7e-05 Identities = 40/251 (15%), Positives = 77/251 (30%), Gaps = 31/251 (12%) Query: 402 PLPETTSQVLAARQQLQRVQGATKAKKSEPAA----ATRARPVNNAALERLASVTDRVQA 457 P E +Q + + + P+ AR + A + A T Sbjct: 983 PEVEKRNQTVDTTN----ITTPNNIQADVPSVPSNNEEIARV-DEAPVPPPAPATPSETT 1037 Query: 458 RPVPSALEKAPAKKEAYRWKATTPVMQQKE--------VVATPKALKKA---LEHEKTPE 506 V ++ E AT Q +E V A + + A E ++T Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 507 LAVKLAA---------EAIERDPWAAQVSQLSLPKLVEQVALNAWKE-ESDNAVCLHLRS 556 K A E+ +V+ PK + + E +N ++++ Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 557 SQRHLNNRGAQQKLAEALS-MLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARES 615 Q N ++ A+ S ++ E T V N V P A + + + Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSN 1217 Query: 616 IIADNNIQTLR 626 + + +++R Sbjct: 1218 KPKNRHRRSVR 1228
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 385 bits (990), Expect = e-137 Identities = 125/310 (40%), Positives = 175/310 (56%), Gaps = 16/310 (5%) Query: 2 KTLVVALGGNALLQRGEALTAENQYRNIASAVPALARL-ARSYRLAIVHGNGPQVGLLAL 60 K +V+ALGGNAL QRG+ + E N+ +A + AR Y + I HGNGPQVG L L Sbjct: 3 KRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLLL 62 Query: 61 QNLAWKE---VEPYPLDVLVAESQGMIGYMLAQSLSAQPQM----PPVTTVLTRIEVSPD 113 A + + P+DV A SQG IGYM+ Q+L + + V T++T+ V + Sbjct: 63 HMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDKN 122 Query: 114 DPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRD-GKYLRRVVASPQPRKILDSEAIELL 172 DPAF P K +GP Y E + L GW +K D G+ RRVV SP P+ +++E I+ L Sbjct: 123 DPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKL 182 Query: 173 LKEGHVVICSGGGGVPVTEDG---AGSEAVIDKDLAAALLAEQINADGLVILTDADAVYE 229 ++ G +VI SGGGGVPV + G EAVIDKDLA LAE++NAD +ILTD + Sbjct: 183 VERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAAL 242 Query: 230 NWGTPQQRAIRHATPDELAPFAKAD----GSMGPKVTAVSGYVRSRSKPAWIGALSRIEE 285 +GT +++ +R +EL + + GSMGPKV A ++ + A I L + E Sbjct: 243 YYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLEKAVE 302 Query: 286 TLAGEAGTCI 295 L G+ GT + Sbjct: 303 ALEGKTGTQV 312
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.4 bits (66), Expect = 0.031 Identities = 16/150 (10%), Positives = 44/150 (29%), Gaps = 8/150 (5%) Query: 299 RSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTP----- 353 + ++ +L QAR R R + P E F +++ Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192 Query: 354 EAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEV 413 E +S + + + A + + + + + + + + F + Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSS---LLHKQAI 249 Query: 414 AEIEALIQQRLDARKAKDWAAADAARDRLN 443 A+ L Q+ + + +++ Sbjct: 250 AKHAVLEQENKYVEAVNELRVYKSQLEQIE 279
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 133 bits (336), Expect = 9e-39 Identities = 59/167 (35%), Positives = 89/167 (53%), Gaps = 16/167 (9%) Query: 11 QRYTWCL------AGICYSSLAILPSFLSY-----AESYFNPAFLLENGTSVADLSRFER 59 QR T CL + L + +F + AE YFNP FL ++ +VADLSRFE Sbjct: 10 QRNTQCLHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFEN 69 Query: 60 GNHQPAGVYRVDLWRNDEFIGSQDIVFESTTENTGDKSGGLMPCFNQVLLERIGLNSSAF 119 G P G YRVD++ N+ ++ ++D+ F NTGD G++PC + L +GLN+++ Sbjct: 70 GQELPPGTYRVDIYLNNGYMATRDVTF-----NTGDSEQGIVPCLTRAQLASMGLNTASV 124 Query: 120 PELAQQQNNKCINLLKAVPDATINFDFAAMRLNITIPQIALLSSAHG 166 + ++ C+ L + DAT D RLN+TIPQ + + A G Sbjct: 125 SGMNLLADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARG 171
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 56.4 bits (136), Expect = 2e-15 Identities = 18/50 (36%), Positives = 27/50 (54%) Query: 1 MLTKYALVAVIVLCLTVLGFTLLAGDSLCEFTVKERNIEFRAVLAYEPKK 50 + + V+++CLT+L FT L SLCE ++ E A +AYE K Sbjct: 3 LPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK 52
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 275 bits (705), Expect = 7e-97 Identities = 105/183 (57%), Positives = 130/183 (71%), Gaps = 1/183 (0%) Query: 4 MKTTHTSLPFAGHTLHFVEFDPANFCEQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYA 63 M T+H LPFAGH LH V+FD ++F E DLLWLPH+ +L+ AGRKRK EHLAGRIAAV+A Sbjct: 1 MLTSHFPLPFAGHRLHIVDFDASSFREHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHA 60 Query: 64 LREYGYKCVPAIGELRQPVWPAEVYGSISHCGATALAVVSRQPIGVDIEEIFSAQTATEL 123 LRE G + VP +G+ RQP+WP ++GSISHC TALAV+SRQ IG+DIE+I S TATEL Sbjct: 61 LREVGVRTVPGMGDKRQPLWPDGLFGSISHCATTALAVISRQRIGIDIEKIMSQHTATEL 120 Query: 124 TDNIITPAEHERLADCGLAFSLALTLAFSAKESAFKA-SEIQTDAGFLDYQIISWNKQQV 182 +II E + L L F LALTLAFSAKES +KA S+ T GF ++ S + Sbjct: 121 APSIIDSDERQILQASLLPFPLALTLAFSAKESVYKAFSDRVTLPGFNSAKVTSLTATHI 180 Query: 183 IIH 185 +H Sbjct: 181 SLH 183
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.7 bits (85), Expect = 1e-04 Identities = 81/391 (20%), Positives = 142/391 (36%), Gaps = 38/391 (9%) Query: 27 FISIVSLGLLGVAVPVQIQMMTHSTWQV---GLSVTLTGGAMFVGLMVGGVLADRYERKK 83 + V +GL+ +P ++ + HS G+ + L F V G L+DR+ R+ Sbjct: 15 ALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRP 74 Query: 84 VILLARGTCGIGFIGLCLNALL--PEPSLLAIYLLGLWDGFFASLGVTALLAATSALVGR 141 V+L + G ++ + P L +Y+ + G + G A A + + Sbjct: 75 VLL-------VSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVA-GAYIADITDG 126 Query: 142 ENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPE-LP 200 + + G V P++GGL+ A + AA L LPE Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHK 186 Query: 201 PPPQPLEHPLKSLLAGFRFLLASPLLGGLLTMA----------SAVLVLYPALADNWQMS 250 +PL + LA FR+ ++ L+ + +A+ V++ D + Sbjct: 187 GERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG--EDRFHWD 244 Query: 251 AAQIGFLYAAIP-LGAAIGALTSGKLAHSARPGLLMLLSTLGS---FLAIGLFGLMPMWI 306 A IG AA L + A+ +G +A ++L + ++ + M Sbjct: 245 ATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAF 304 Query: 307 LGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGA 366 +V LA G ML Q E G++ G A +G L + A Sbjct: 305 PIMVLLASGGIGMPALQ----AMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYA 360 Query: 367 MMTPVASASASGFGLLIIGVLLLLVLVELRR 397 + + +G+ + L LL L LRR Sbjct: 361 ----ASITTWNGWAWIAGAALYLLCLPALRR 387
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 63.0 bits (153), Expect = 2e-13 Identities = 61/285 (21%), Positives = 102/285 (35%), Gaps = 35/285 (12%) Query: 40 HTLESQPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQ 99 H P RIV+ LLA+ VAD + R W E L Sbjct: 29 HAAAIDPNRIVALEWLPVELLLALGIVPYG---------VADTINY-RLW---VSEPPLP 75 Query: 100 RLYIG-----EPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKS--- 151 I EP+ E + P ++ SA G S + L+ IAP N+ D Sbjct: 76 DSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPS----PEMLARIAPGRGFNFSDGKQPL 131 Query: 152 --WQSLLTQLGEITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLW 209 + LT++ ++ + A +AQ++ + + K + + ++ Sbjct: 132 AMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVF 191 Query: 210 TPESAQGQMLEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQ 269 P S ++L++ G NA Q + + + LAA + + L + Sbjct: 192 GPNSLFQEILDEYGIP--------NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNS 243 Query: 270 KDADAIYANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQVLERL 314 KD DA+ A PL +P V+ + + F SAM + L Sbjct: 244 KDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVL 288
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 444 bits (1142), Expect = e-161 Identities = 146/299 (48%), Positives = 195/299 (65%), Gaps = 18/299 (6%) Query: 1 MAIPKLQAYALPESHDIPQNKVDWAFEPQRAALLIHDMQDYFVSFWGENCPMMEQVIANI 60 MAIP +Q Y +P + D+PQNKV W +P RA LLIHDMQ+YFV + + ++ ANI Sbjct: 1 MAIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANI 60 Query: 61 AALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRSPEQQKVVDRLTPDADDTV 120 L++ C Q IPV YTAQP Q+ +DRALL D WGPGL P ++K++ L P+ DD V Sbjct: 61 RKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLV 120 Query: 121 LVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTTATDAFMRDIKPFMVADALAD 180 L KWRYSAF R+ L +M+++ GR+QLIITG+YAHIGC+ TA +AFM DIK F V DA+AD Sbjct: 121 LTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVAD 180 Query: 181 FSRDEHLMSLKYVAGRSGRVVMTEELL------PAPIPASKA-----------ALREVIL 223 FS ++H M+L+Y AGR VMT+ LL PA + + A +R+ I Sbjct: 181 FSLEKHQMALEYAAGRCAFTVMTDSLLDQLQNAPADVQKTSANTGKKNVFTCENIRKQIA 240 Query: 224 PLLDESDEPFDDD-NLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLS 281 LL E+ E D +L+D GLDSVR+M L +WR+ ++ FV LA+ PTI+ W KLL+ Sbjct: 241 ELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEWQKLLT 299
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 359 bits (922), Expect = e-129 Identities = 108/258 (41%), Positives = 149/258 (57%), Gaps = 20/258 (7%) Query: 5 GKNVWVTGAGKGIGYATALTFVEAGAKVTGFD---------------QAFTQEQYPFATE 49 GK ++TGA +GIG A A T GA + D +A E +P Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP---- 63 Query: 50 VMDVADAGQVAQVCQRLLAETERLDVLINAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 DV D+ + ++ R+ E +D+L+N AG+LR G LS E+W+ TF+VN G FN Sbjct: 64 -ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTARIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + +R G+IVTV S+ A R M+AY +SKAA +GLELA +RC Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N+VSPGST+TDMQ +LW ++ EQ I+G E FK GIPL K+A+P +IA+ +LFL S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 230 ASHITLQDIVVDGGSTLG 247 A HIT+ ++ VDGG+TLG Sbjct: 243 AGHITMHNLCVDGGATLG 260
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 26.7 bits (59), Expect = 0.013 Identities = 7/45 (15%), Positives = 16/45 (35%), Gaps = 1/45 (2%) Query: 6 KRYPEEFKTEAVKQVVDR-GYSVASVATRLDITTHSLYAWIKKYG 49 R E + + + + A L + ++L I++ G Sbjct: 430 DRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELG 474
>BCTLIPOCALIN#Bacterial lipocalin signature. Length = 171 Score = 28.4 bits (63), Expect = 0.019 Identities = 18/98 (18%), Positives = 39/98 (39%), Gaps = 13/98 (13%) Query: 50 QGITIIKTFDAPGGMKGYLGKYQDMGVTIYLTPDGKHAISG--YMYNEKGENLSNTLIEK 107 + + + F+ YLGK+ ++ + G ++ + N+ G ++ N Sbjct: 21 ESVKPVSDFEL----NNYLGKWYEVARLDHSFERGLSQVTAEYRVRNDGGISVLN----- 71 Query: 108 EIYAPAGREMWQRMEQSHWLLDGKKDAPVIVYVFSDPF 145 Y+ + W+ E + ++G D + V F PF Sbjct: 72 RGYSEE-KGEWKEAEGKAYFVNGSTDGYLKVSFFG-PF 107
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 116 bits (292), Expect = 5e-34 Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 4/119 (3%) Query: 55 EEQARLQMQQLQQNNIVYFDLDKYDIRSDFAQMLDAHANFLRSN--PSYKVTVEGHADER 112 +Q + + V F+ +K ++ + LD + L + V V G+ D Sbjct: 205 APAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRI 264 Query: 113 GTPEYNISLGERRANAVKMYLQGKGVSADQISIVSYGKEKPAVLGHDEAAYSKNRRAVL 171 G+ YN L ERRA +V YL KG+ AD+IS G+ P V G+ K R A++ Sbjct: 265 GSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNP-VTGN-TCDNVKQRAALI 321
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 63.5 bits (154), Expect = 7e-13 Identities = 39/210 (18%), Positives = 70/210 (33%), Gaps = 9/210 (4%) Query: 79 EQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEVAA 138 E+R A+ + +E E A +E + AE + Sbjct: 986 EKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSK 1045 Query: 139 AKAAADAKAAEEAAKKAAADAKKKAEAEAAKAAAEAQKKAEVAAAALKKKAEAAEAAAAE 198 ++ K E+ A + A ++ A+ + A Q EVA + +E E E Sbjct: 1046 QESKTVEKN-EQDATETTAQNREVAKEAKSNVKANTQT-NEVA----QSGSETKETQTTE 1099 Query: 199 ARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEKAAADKAAADKKAAA 258 ++ A E EKAK E EK K + E++ + AE A + Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTV---NIK 1156 Query: 259 EKAAADKKAAAAKAAAEKAAAAKAAAEADD 288 E + A + A++ ++ + Sbjct: 1157 EPQSQTNTTADTEQPAKETSSNVEQPVTES 1186 Score = 55.1 bits (132), Expect = 3e-10 Identities = 30/244 (12%), Positives = 81/244 (33%), Gaps = 20/244 (8%) Query: 51 DAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAE-ELREKQAAEQER------L 103 D V A + ++ ++K+ + + EQ A E + ++ A++ + Sbjct: 1021 DEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT 1080 Query: 104 KQLEKERLAAQEQKKQAEEAAKQAELKQKQAEVAAAKAAADAKAAEEAAKKAAADAKKKA 163 + E + ++ ++ Q K+ +K+ KA + + +E K + + K+ Sbjct: 1081 QTNEVAQSGSETKETQ-TTETKETATVEKE-----EKAKVETEKTQEVPKVTSQVSPKQE 1134 Query: 164 EAEAAKAAAEAQKKAEVAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEK 223 ++E + AE ++ + E + + A++ + E+ Sbjct: 1135 QSETVQPQAEPARENDPTVN-------IKEPQSQTNTTADTEQPAKETSSNVEQPVTEST 1187 Query: 224 AAADKKAAAEKAAADKKAAEKAAADKAAADKKAAAEKAAADKKAAAAKAAAEKAAAAKAA 283 + E A + + +++K + + + A + Sbjct: 1188 TVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTV 1247 Query: 284 AEAD 287 A D Sbjct: 1248 ALCD 1251 Score = 54.7 bits (131), Expect = 5e-10 Identities = 33/221 (14%), Positives = 76/221 (34%), Gaps = 8/221 (3%) Query: 66 RMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAK 125 R ++E+ + + + Q+ E +E Q E + +EKE A E +K E Sbjct: 1066 REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKV 1125 Query: 126 QAELKQKQAEVAAAKAAADAKAAEEAAKKAAADAKKKAEAEAAKAAAEAQKKAEVAAAAL 185 +++ KQ ++ AE A + K+ +++ A Q E ++ Sbjct: 1126 TSQVSPKQ-----EQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVE 1180 Query: 186 KKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEKA 245 + E+ + + ++ K + + + + A + Sbjct: 1181 QPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTS 1240 Query: 246 AADKAAADKKAAAEKAAADKKAAAAKAAAEKAAAAKAAAEA 286 + D++ A + + + A + A A+ A +A Sbjct: 1241 SNDRSTV---ALCDLTSTNTNAVLSDARAKAQFVALNVGKA 1278 Score = 52.4 bits (125), Expect = 3e-09 Identities = 32/184 (17%), Positives = 67/184 (36%), Gaps = 12/184 (6%) Query: 99 EQERLKQLEKERLAAQEQKKQAEEAAKQAELKQK----QAEVAAAKAAADAKAAEEAAK- 153 E E+ Q QA+ + + ++ +A V A ++ E A+ Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN 1043 Query: 154 -KAAADAKKKAEAEAAKAAAEAQKKAEVAAAALKKKAEAAEAAAAEARKKAATEAAEKAK 212 K + +K E +A + A+ ++ A+ A + +K + E A ++ +E E Sbjct: 1044 SKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVA------QSGSETKETQT 1097 Query: 213 AEAEKKAAAEKAAADKKAAAEKAAADKKAAEKAAADKAAADKKAAAEKAAADKKAAAAKA 272 E ++ A EK K + K ++ + + + + AE A + K Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 273 AAEK 276 + Sbjct: 1158 PQSQ 1161 Score = 47.4 bits (112), Expect = 9e-08 Identities = 29/213 (13%), Positives = 68/213 (31%), Gaps = 6/213 (2%) Query: 71 ESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAELK 130 +S ++ + Q ++ A E EK E E+ +++ K +++Q+E QAE Sbjct: 1087 QSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPA 1146 Query: 131 QKQAEVAAAKAAADAKAAEEAAKKAAADAKKKAEAEAAKAAAEAQKKAEVAAAALKKKAE 190 ++ K ++ A + E ++ + V A Sbjct: 1147 RENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPAT 1206 Query: 191 AAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEKAAADKA 250 +E+ K ++ A ++ D+ A + Sbjct: 1207 TQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTN------TNAV 1260 Query: 251 AADKKAAAEKAAADKKAAAAKAAAEKAAAAKAA 283 +D +A A+ A + A ++ ++ + Sbjct: 1261 LSDARAKAQFVALNVGKAVSQHISQLEMNNEGQ 1293 Score = 40.4 bits (94), Expect = 1e-05 Identities = 22/156 (14%), Positives = 44/156 (28%), Gaps = 11/156 (7%) Query: 126 QAELKQKQAEVAAAKAAADAKAAEEAAK-KAAADAKKKAEAEAAKAAAEAQKKAEVAAAA 184 + E + + + + +A + A+ A A + E A Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN 1043 Query: 185 LKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEK 244 K++++ E K +A E E A+ E A + + E Sbjct: 1044 SKQESKTVE--------KNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKET 1095 Query: 245 AAADKAAADKKAAAEKAAA--DKKAAAAKAAAEKAA 278 + EKA +K K ++ + Sbjct: 1096 QTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSP 1131
>PF05272#Virulence-associated E family protein Length = 892 Score = 53.9 bits (129), Expect = 2e-09 Identities = 30/82 (36%), Positives = 48/82 (58%), Gaps = 2/82 (2%) Query: 4 SELSDLLWAQVDRVAPHLLPNGKIEGHEWVAGNVNGDKGNSLKVNLIGKKKWADFAEGDG 63 + L+D L + + P LP G + GHE+ G++ G KG+S KVN + KW DF+ G+ Sbjct: 12 TSLADALLTRAKDLLPEWLPGGVLVGHEYECGSLAGGKGDSCKVN-VTTGKWCDFSTGES 70 Query: 64 G-DMLDLWMACRGINLHQAMQE 84 G D+LDL+ G+ + +A + Sbjct: 71 GRDLLDLYAEIHGLKVSKAAAQ 92
>FIMREGULATRY#Escherichia coli: P pili regulatory PapB protein signature. Length = 104 Score = 26.8 bits (59), Expect = 0.014 Identities = 8/31 (25%), Positives = 15/31 (48%) Query: 71 LVDYYVFGMTFMTLARKHGCSDGYIGKKLQK 101 + DY V G + + K+ ++GY L + Sbjct: 51 MKDYLVGGHSRKEVCEKYQMNNGYFSTTLGR 81
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 39.8 bits (93), Expect = 6e-05 Identities = 14/194 (7%), Positives = 43/194 (22%), Gaps = 12/194 (6%) Query: 29 LNGAASDAERSSARMQRFMERQTQAARQTMQAASSAATAASAHAQTVEKNARAHERMARE 88 L ++A+ + Q + + Q S + + E Sbjct: 127 LTALGAEADTLKTQSSL---LQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEE 183 Query: 89 VEQTRLRVDALNQKMREEQAQARALAEAQDKAAAAFYRQIDSVKQAGAGLQELQRIQQQI 148 V + + + ++ Q + + +I+ + + Sbjct: 184 VLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDD---F 240 Query: 149 RQARNSGGVGQQDYLALISEITAKTRALTQAE------EQATRQKAAFIRQLKEQATRQN 202 + + + L ++ L + E + + + + Sbjct: 241 SSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEI 300 Query: 203 LSSSELLRARAAQL 216 L L Sbjct: 301 LDKLRQTTDNIGLL 314 Score = 38.7 bits (90), Expect = 1e-04 Identities = 25/224 (11%), Positives = 63/224 (28%), Gaps = 30/224 (13%) Query: 545 NYQEQQKRRNAENAALNRMNETEAARHQREIARINAMQYADQAVRDAAIQRENERYEKAI 604 + + + A L + + E+ ++ ++ D+ + E R I Sbjct: 133 EADTLKTQSSLLQARLEQ-TRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLI 191 Query: 605 KKNTRATRNDEATRLLLQYSQQQAQVEGQIAAARQSAGIATERMTEAHKQLLALQQRISD 664 K+ + Q+ Q E + R R+ + R+ D Sbjct: 192 KEQ------------FSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDD 239 Query: 665 LDGKKLTADEKSVLARKNELIQALTLLDVKQQELQKQTALNDLRKKTVQLTSQLADKERA 724 L + I +L+ + + ++ L + + Q+ S++ + Sbjct: 240 F--SSL---------LHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEE 288 Query: 725 LREQHNLDIATAGMGDKQRQRYQAQLRIRQEYRQQLQQLENDSR 768 + + + Q I +L + E + Sbjct: 289 YQ-LVTQLFKN----EILDKLRQTTDNIGL-LTLELAKNEERQQ 326 Score = 32.5 bits (74), Expect = 0.009 Identities = 31/238 (13%), Positives = 69/238 (28%), Gaps = 42/238 (17%) Query: 402 DPVNAAKALDNALHFLNATQLEQIRVLGEQGRSSDAARIAMSALAEETGKRTSDIDNNLN 461 + A L +LEQ R RS + ++ L +E + + L Sbjct: 128 TALGAEADTLKTQSSLLQARLEQTRYQILS-RSIELNKLPELKLPDEPYFQNVSEEEVLR 186 Query: 462 ALGSTLQTLSDWWKQFWDAAMNIGREDSLDAQIDALQEKIQRAKKYPWTNASTQVEYDQQ 521 + S W Q + +N+ D A+ + +I R + ++ Sbjct: 187 LTSLIKEQFSTWQNQKYQKELNL---DKKRAERLTVLARINRYEN--------LSRVEKS 235 Query: 522 RLNDLQEKKRRKDLQDAKAQAERNYQEQQKRRNAENAALNRMNETEAARHQREIARINAM 581 RL+D L +A A+ EQ+ + L +++ + Sbjct: 236 RLDDFSS------LLHKQAIAKHAVLEQENKYVEAVNELRVY-----------KSQLEQI 278 Query: 582 QYADQAVRDAAIQRENERYEKAIKKNTRATRNDEATRLLLQYSQQQAQVEGQIAAARQ 639 + + ++ + + K + T + ++A + Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTT-------------DNIGLLTLELAKNEE 323 Score = 31.0 bits (70), Expect = 0.030 Identities = 26/185 (14%), Positives = 57/185 (30%), Gaps = 13/185 (7%) Query: 13 IDAAEFKNEIPRIKNLLNGAASDAERSSARMQRFMERQTQAARQTMQAASSAATAASAHA 72 + E + +E R+ ++ Q + A Sbjct: 157 SRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAER 216 Query: 73 QTVEKNARAHERMAREVEQTRLRVDALNQKMREEQAQARALAEAQDKAAAAFYRQIDSVK 132 TV +E ++R VE++RL + +QA A+ Q+ ++ Sbjct: 217 LTVLARINRYENLSR-VEKSRL---DDFSSLLHKQAIAKHAVLEQENKYVEAVNEL---- 268 Query: 133 QAGAGLQELQRIQQQIRQARNSGGVGQQDYLALISEITAKTRA-LTQAEEQATRQKAAFI 191 +L++I+ +I A+ + Q + I + +T + + K Sbjct: 269 --RVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLE--LAKNEER 324 Query: 192 RQLKE 196 +Q Sbjct: 325 QQASV 329
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 134 bits (339), Expect = 2e-42 Identities = 62/200 (31%), Positives = 98/200 (49%), Gaps = 30/200 (15%) Query: 1 MRKLYAAILSAAICLAVSGAPAWASEHRSTLSAGYLHASTNAPGSDDLNGINVKYRYEFT 60 M+K+ AA+ +G A+ ST++ GY + + + G N+KYRYE Sbjct: 1 MKKIACLSALAAVLAFTAGTSVAAT---STVTGGYAQSDAQGQMNK-MGGFNLKYRYEED 56 Query: 61 DT-LGLVTSFSYANAEDEQKTHYSDTRWHEDSVRNRWFSVMAGLSVRVNEWFSAYAMAGV 119 ++ LG++ SF+Y T S T D +N+++ + AG + R+N+W S Y + GV Sbjct: 57 NSPLGVIGSFTY--------TEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGV 108 Query: 120 AYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDNRHSNTSLAWGAGVQFNPTESVAIDLAYE 179 Y + T T+ HD S+ ++GAG+QFNP E+VA+D +YE Sbjct: 109 GYGKFQT--------TEYPTYKHD---------TSDYGFSYGAGLQFNPMENVALDFSYE 151 Query: 180 GSGSGDWRTDGFIVGVGYKF 199 S +I GVGY+F Sbjct: 152 QSRIRSVDVGTWIAGVGYRF 171
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.010 Identities = 9/18 (50%), Positives = 12/18 (66%) Query: 31 LVLLGPSGAGKSSLLRVL 48 +VL G G GKS+L+ L Sbjct: 599 VVLEGTGGIGKSTLINTL 616
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.4 bits (97), Expect = 7e-06 Identities = 9/74 (12%), Positives = 33/74 (44%), Gaps = 1/74 (1%) Query: 16 LRKQQSRLRQYACQVAGYEQEIERLKAQLDRLRRMLFGQSSEKKRHKLENQIRQAEKRLS 75 + +Q+++ + ++ Y+ ++E++++++ + + K L+ ++RQ + Sbjct: 254 VLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILD-KLRQTTDNIG 312 Query: 76 ELENRLNTARNLLE 89 L L + Sbjct: 313 LLTLELAKNEERQQ 326
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 61.8 bits (150), Expect = 4e-17 Identities = 20/48 (41%), Positives = 34/48 (70%) Query: 23 QKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFVDYESRK 70 + +++ ++++CLT+++ +TRK LCE+R R G EVA F+ YES K Sbjct: 5 RSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK 52
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 822 bits (2125), Expect = 0.0 Identities = 414/862 (48%), Positives = 570/862 (66%), Gaps = 18/862 (2%) Query: 15 GVPSFIGGLVVFVSAAFNAQAETWFDPAFFKDDPSMVADLSRFEKGQKITPGVYRVDIVL 74 G + F + A + AE +F+P F DDP VADLSRFE GQ++ PG YRVDI L Sbjct: 25 GFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYL 84 Query: 75 NQTIVDTRNVNFVEITPEKGIAACLTTESLDAMGVNTDAFPAFKQLDKQVCVPLAEIIPD 134 N + TR+V F E+GI CLT L +MG+NT + L CVPL +I D Sbjct: 85 NNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHD 144 Query: 135 ASVTFNVNKLRLEISVPQIAIKSNARGYVPPERWDEGINALLLGYSFSGANSIHSSADSD 194 A+ +V + RL +++PQ + + ARGY+PPE WD GINA LL Y+FSG + + + Sbjct: 145 ATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNS 204 Query: 195 SGDSYFLNLNSGVNLGPWRLRNNSTWSR-----SSGQTAEWKNLSSYLQRAVIPLKGELT 249 +LNL SG+N+G WRLR+N+TWS SSG +W++++++L+R +IPL+ LT Sbjct: 205 --HYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLT 262 Query: 250 VGDDYTAGDFFDSVSFRGVQLASDDNMLPDSLKGFAPVVRGIAKSNAQITIKQNGYTIYQ 309 +GD YT GD FD ++FRG QLASDDNMLPDS +GFAPV+ GIA+ AQ+TIKQNGY IY Sbjct: 263 LGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYN 322 Query: 310 TYVSPGAFEISDLYSTSSSGDLLVEIKEADGSVNSYSVPFSSVPLLQRQGRIKYAVTLAK 369 + V PG F I+D+Y+ +SGDL V IKEADGS ++VP+SSVPLLQR+G +Y++T + Sbjct: 323 STVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGE 382 Query: 370 YRTNSNEQQESKFAQTTLQWGGPWGTTWYGGGQYAEYYRAAMFGLGFNLGDFGAISFDAT 429 YR+ + +Q++ +F Q+TL G P G T YGG Q A+ YRA FG+G N+G GA+S D T Sbjct: 383 YRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMT 442 Query: 430 QAKSTLADQSEHKGQSYRFLYAKTLNQLGTNFQLMGYRYSTSGFYTLSDTMYKHMDGY-- 487 QA STL D S+H GQS RFLY K+LN+ GTN QL+GYRYSTSG++ +DT Y M+GY Sbjct: 443 QANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNI 502 Query: 488 EFNDGDDEDTPMWSRYYNLFYTKRGKLQVNISQQLGEYGSFYLSGSQQTYWHTDQQDRLL 547 E DG + P ++ YYNL Y KRGKLQ+ ++QQLG + YLSGS QTYW T D Sbjct: 503 ETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQF 562 Query: 548 QFGYNTQIKDLSLGVSWNYSKSRGQPDADQVFALNFSLPLNLLLPRSNDSYTRKKNYAWM 607 Q G NT +D++ +S++ +K+ Q DQ+ ALN ++P + L + S R +A Sbjct: 563 QAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWR---HASA 619 Query: 608 TSNTSIDNEGHITQNLGLTETLLDDGNLSYSVQQGYNSEGKTANGS---ASMDYKGAFAD 664 + + S D G +T G+ TLL+D NLSYSVQ GY G +GS A+++Y+G + + Sbjct: 620 SYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGN 679 Query: 665 ARVGYNYSDNGSQQQLNYALSGSLVAHSQGITLGQSLGETNVLIAAPGAENTRVANSTGL 724 A +GY++SD+ +QL Y +SG ++AH+ G+TLGQ L +T VL+ APGA++ +V N TG+ Sbjct: 680 ANIGYSHSDD--IKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGV 737 Query: 725 KTDWRGYTVVPYATSYRENRIALDAASLKRNVDLENAVVNVVPTKGALVLAEFNAHAGAR 784 +TDWRGY V+PYAT YRENR+ALD +L NVDL+NAV NVVPT+GA+V AEF A G + Sbjct: 738 RTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIK 797 Query: 785 VLMKTSKQGIPLRFGAIATLDGIQTNSGIIDDDGSLYMSGLPAQGAITVRWGEAPDQICH 844 +LM + PL FGA+ T + +SGI+ D+G +Y+SG+P G + V+WGE + C Sbjct: 798 LLMTLTHNNKPLPFGAMVTSES-SQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV 856 Query: 845 ISYQLTEQQINSAITRMDAICR 866 +YQL + +T++ A CR Sbjct: 857 ANYQLPPESQQQLLTQLSAECR 878
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 98.2 bits (244), Expect = 4e-23 Identities = 142/655 (21%), Positives = 227/655 (34%), Gaps = 93/655 (14%) Query: 137 DVDITTHGDNAHAIAARQGTVSFNQGEIYTTGPDAAIAKIYNGGTVTLKNTSAVAHQGSG 196 D + + +V Q + AAI + G VT+ S A G+ Sbjct: 285 PGGFGPVLDGWYGVDVSGSSVELAQSIVEAPELGAAIR-VGRGARVTVSGGSLSAPHGNV 343 Query: 197 IVLESSIN--GQEATVDILSGSSLRSANEILYHKDETSNVTITDSEVSSAADVFINNIKG 254 I + Q A + I + + + L ++ V +T ++ AD + + Sbjct: 344 IETGGARRFAPQAAPLSITLQAGAHAQGKALLYRVLPEPVKLT---LTGGADAQGDIVAT 400 Query: 255 HLTVDATNSKITGSANISTDDN------THTYLSLS-DNSTWDIKADSTVSNLTV--DNS 305 L S G +++ T SLS DN+TW + +S V L + D S Sbjct: 401 ELPSIPGTS--IGPLDVALASQARWTGATRAVDSLSIDNATWVMTDNSNVGALRLASDGS 458 Query: 306 TVYISRADGRDVEPTRLTITENYVGNNGVLHLRTELDDDNSATDKVVINGNTSGTTRVKV 365 + A+ + +T N + +G+ + D +DK+V+ + SG R+ V Sbjct: 459 VDFQQPAEAGRFK----VLTVNTLAGSGLFRMNVFAD--LGLSDKLVVMQDASGQHRLWV 512 Query: 366 TNAGGSGAYTLNGIEIISVEGESNGEFI---KDSRIFAGAYEYSLTRGNTEATNKNWYLT 422 N+G S + N + ++ S F KD ++ G Y Y L N W L Sbjct: 513 RNSG-SEPASANTLLLVQTPLGSAATFTLANKDGKVDIGTYRYRLA----ANGNGQWSLV 567 Query: 423 NFQAT-------SGGETNSGGSSAPTVAPTPVLRPEAGSYVANLAAANTLFVMRLNDRAG 475 +A G AP P A AA NT V A Sbjct: 568 GAKAPPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELSAAANAAVNTGGV----GLAS 623 Query: 476 EMRYIDPVTEQERSSRLWLRQIGGHNAWRDSNGQLRTTSHRY-------VS--QLGGDLL 526 + Y + +R L L G AW Q + +R V+ +LG D Sbjct: 624 TLWYAESNALSKRLGELRLNPDAG-GAWGRGFAQRQQLDNRAGRRFDQKVAGFELGADHA 682 Query: 527 TGGFTDSDSWRLGVMAGYARDYNLTHSSVSDYRSKGSVRGYSAGLYATWFADDISKKGAY 586 W LG +AGY R + G G YAT+ AD G Y Sbjct: 683 VAVAGGR--WHLGGLAGYTR----GDRGFTGDGG-GHTDSVHVGGYATYIADS----GFY 731 Query: 587 IDSWAQYSWFKN----------SVKGDELAYESYSAKGATVSLEAGYGFALNKSFGLEAA 636 +D+ + S +N +VKG Y G SLEAG F Sbjct: 732 LDATLRASRLENDFKVAGSDGYAVKGK------YRTHGVGASLEAGRRFTHADG------ 779 Query: 637 KYTWIFQPQAQAIWMGVDHNAHTEANGSRIENDANNNIQTRLGFRTFIRTQEKNSGPHGD 696 W +PQA+ A+ ANG R+ ++ +++ RLG R + G Sbjct: 780 ---WFLEPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLEVGKRIELAG----GR 832 Query: 697 DFEPFVEMNWIHNSK-DFAVSMNGVKVEQDGVSNLGEIKLGVNGNLNPAASVWGN 750 +P+++ + + V NG+ + E+ LG+ L S++ + Sbjct: 833 QVQPYIKASVLQEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALGRGHSLYAS 887
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.008 Identities = 9/16 (56%), Positives = 11/16 (68%) Query: 55 VVGESGCGKSTFARAI 70 + GESG GK ARA+ Sbjct: 165 ITGESGTGKELVARAL 180
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 31.2 bits (70), Expect = 4e-04 Identities = 16/57 (28%), Positives = 20/57 (35%), Gaps = 2/57 (3%) Query: 41 GPMPAVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPYVAAGVYEHVSVKPFKKV 97 P+PA G GS E + EA W +P A V +V KV Sbjct: 268 APLPA--EGKFAVIGGLGSVAGFEKNTREAVDRWIQENPNAAETVEAVFNVAAAAKV 322
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 256 bits (654), Expect = 2e-88 Identities = 236/239 (98%), Positives = 237/239 (99%) Query: 4 ITLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQA 63 +TLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMV PADLEPPQA Sbjct: 1 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQA 60 Query: 64 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR 123 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR Sbjct: 61 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR 120 Query: 124 PASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 183 PASPFENTAPAR TSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF Sbjct: 121 PASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 180 Query: 184 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ 242 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ Sbjct: 181 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ 239
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 342 bits (879), Expect = e-117 Identities = 125/341 (36%), Positives = 182/341 (53%), Gaps = 23/341 (6%) Query: 11 DNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKELIASRLHYLSSRWQGPFISLNC 70 L+G + + E+ ++ L D ++I GE GTGKEL+A LH R GPF+++N Sbjct: 137 MPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINM 196 Query: 71 AALNENLLDSELFGHEAGAFTGAQKLHPGRFERADGGTLFLDELATAPMMVQEKLLRVIE 130 AA+ +L++SELFGHE GAFTGAQ GRFE+A+GGTLFLDE+ PM Q +LLRV++ Sbjct: 197 AAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQ 256 Query: 131 YGELERVGGSQPLQVNVRLVCATNADLPAMVNEGTFRADLLDRLAFDVVQLPPLRERESD 190 GE VGG P++ +VR+V ATN DL +N+G FR DL RL ++LPPLR+R D Sbjct: 257 QGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAED 316 Query: 191 IMLMAEHFAIQMCREIKLPLFPGFTERARETLLNYRWPGNIRELKNVVERSVYRHGTSDY 250 I + HF Q +E F + A E + + WPGN+REL+N+V R + Sbjct: 317 IPDLVRHFVQQAEKEGLDVK--RFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVI 374 Query: 251 PLDDIIID---PFKRRPPEEAIAVSENTSLPTLPLD------------------LREFQM 289 + I + P E+A A S + S+ + Sbjct: 375 TREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLA 434 Query: 290 QQEKELLQLSLQQGKYNQKRAAELLGLTYHQFRALLKKHQI 330 + E L+ +L + NQ +AA+LLGL + R +++ + Sbjct: 435 EMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>MPTASEINHBTR#Metalloprotease inhibitor signature. Length = 122 Score = 24.6 bits (53), Expect = 0.041 Identities = 6/43 (13%), Positives = 16/43 (37%) Query: 30 SGRSELSQSEQQRLAQLVDEAKRMRERIQALESILDAEHPNWR 72 +G+ + + A ++A + + E L + +W Sbjct: 37 AGQLGIEATGSGVCAGPAEQANALAGDVACAEQWLGDKPVSWS 79
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 65.2 bits (159), Expect = 2e-18 Identities = 19/46 (41%), Positives = 32/46 (69%) Query: 23 QKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFTAYEP 68 + +++ ++++CLT+++ +TRK LCE+R R G EVA F AYE Sbjct: 5 RSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYES 50
>adhesinb#Adhesin B signature. Length = 310 Score = 332 bits (852), Expect = e-116 Identities = 90/296 (30%), Positives = 163/296 (55%), Gaps = 7/296 (2%) Query: 1 MLLGCLALTCSIAFQASATEKFKVITTFTIIADMAKNVAGDAAEVSSITKPGAEIHEYQP 60 +G A + + + + K V+ T +IIAD+ KN+AGD + SI G + HEY+P Sbjct: 13 AFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKNIAGDKINLHSIVPVGQDPHEYEP 72 Query: 61 TPGDIKRAQGAQLILANGMNLEL----WFQRFYQHLNGVPE---VIVSSGVTPVGITEGP 113 P D+K+ A LI NG+NLE WF + ++ VS GV + + Sbjct: 73 LPEDVKKTSQADLIFYNGINLETGGNAWFTKLVENAKKKENKDYYAVSEGVDVIYLEGQS 132 Query: 114 YEGKPNPHAWMSPDNALIYVDNIRDALIKYDPANAQTYQRNADTYKAKITQTLAPLRKQI 173 +GK +PHAW++ +N +IY NI L + DPAN +TY++N Y K++ +++ Sbjct: 133 EKGKEDPHAWLNLENGIIYAQNIAKRLSEKDPANKETYEKNLKAYVEKLSALDKEAKEKF 192 Query: 174 TELPENQRWMVTSEGAFSYLARDLGLKELYLWPINADQQGTPQQVRKVVDIVKKNHIPAV 233 +P ++ +VTSEG F Y ++ + Y+W IN +++GTP Q++ +V+ ++K +P++ Sbjct: 193 NNIPGEKKMIVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIKTLVEKLRKTKVPSL 252 Query: 234 FSESTISDKPARQVARETGAHYGGVLYVDSLSTENGPVPTYIDLLKVTTSTLVQGI 289 F ES++ D+P + V+++T ++ DS++ + +Y ++K + +G+ Sbjct: 253 FVESSVDDRPMKTVSKDTNIPIYAKIFTDSVAEKGEEGDSYYSMMKYNLEKIAEGL 308
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 27.7 bits (61), Expect = 0.022 Identities = 18/61 (29%), Positives = 26/61 (42%) Query: 49 QGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRGVTLMGS 108 Q +I L IG + + LPPS ++ N ++ A VS LG +TL G Sbjct: 174 QRSAIVDGGLHIGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPAAVSVLGASELTLDGG 233 Query: 109 Q 109 Sbjct: 234 H 234
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 28.9 bits (64), Expect = 0.021 Identities = 18/81 (22%), Positives = 34/81 (41%), Gaps = 13/81 (16%) Query: 158 ETTSALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKED-----------VLTDGIQTFPDR 206 E ++AL + N D K S S L + F ++V + + V ++ F + Sbjct: 57 EMSAALAQFRNRRDYEKKS-SNLSNSF-ERVLEDEALPKAKQILKLISVHGGALEDFLRQ 114 Query: 207 TDRVYLNPQDCSVINDEALNR 227 ++ +P D ++ E L R Sbjct: 115 ARSLFPDPSDLVLVLRELLRR 135
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.1 bits (65), Expect = 0.041 Identities = 32/142 (22%), Positives = 47/142 (33%), Gaps = 23/142 (16%) Query: 71 MFLGALVGGIIGDKTGRRNAFILYEAIHIASMVVGAFSPNMDF-LIACRFVMDVGLGALL 129 +G V G + D+ G + + I+ V+G + LI RF+ G A Sbjct: 62 FSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFP 121 Query: 130 VTLFAGFTEYMPGRNR----GTWSSRVSFIGNWSYPLCSLIAMGLTPLISA----EWNWR 181 + Y+P NR G S V+ + G+ P I +W Sbjct: 122 ALVMVVVARYIPKENRGKAFGLIGSIVA------------MGEGVGPAIGGMIAHYIHWS 169 Query: 182 VQLLIPAILSLIATALAWRYFP 203 LLIP I I T Sbjct: 170 YLLLIPMI--TIITVPFLMKLL 189
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 31.2 bits (71), Expect = 0.002 Identities = 14/61 (22%), Positives = 28/61 (45%), Gaps = 5/61 (8%) Query: 93 SNKAELTAIIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHR 152 +NK +L A +A T + ++A V A+ + ++ + GE+ + G +R R Sbjct: 2 ANKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAK-----GEKVQLIGFGNFEVRER 56 Query: 153 P 153 Sbjct: 57 A 57
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 60.6 bits (147), Expect = 5e-17 Identities = 19/46 (41%), Positives = 32/46 (69%) Query: 4 QKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFTAYEP 49 + +++ ++++CLT+++ +TRK LCE+R R G EVA F AYE Sbjct: 5 RSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYES 50
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 26.7 bits (58), Expect = 0.048 Identities = 11/31 (35%), Positives = 16/31 (51%) Query: 78 AYGRRQMNKRAEAERIAKEQRLQAERMREEN 108 A + + AEA+R A+EQ Q +R N Sbjct: 218 AANKAREQAAAEAKRKAEEQARQQAAIRAAN 248
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 31.3 bits (71), Expect = 0.007 Identities = 63/331 (19%), Positives = 113/331 (34%), Gaps = 19/331 (5%) Query: 41 FAGLLSDRFGRRPFIMLGMCCYMAFFFDILQTNNIIIAYVFGFLAGMANSFLDAGTYPSL 100 G LSDRFGRRP +++ + + + + + Y+ +AG+ + A + Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATG-AVAGAYI 120 Query: 101 MEAFPRSPGTANI-LIKAFVSSGQFLLPLIISLLVWAELWFGWSFMIAAGIMFINALFLY 159 + + + A G P++ L+ F AA + +N L Sbjct: 121 ADITDGDERARHFGFMSACFGFGMVAGPVLGGLM--GGFSPHAPFFAAAALNGLNFLTGC 178 Query: 160 RCTFPPHPGRRLPV---IKKTTSSTEHRCSIIDLASYTLYGYISMATFYLVSQWLAQYGQ 216 H G R P+ +S + +A+ +I + + +G+ Sbjct: 179 FLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGE 238 Query: 217 FVAGMSYTM-SIKLLSIYTVGSLLCVFITAPLIRNTVRPTTLLMLYTFISFIALFTVCLH 275 T I L + + SL IT P+ L++ IA T + Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALML-----GMIADGTGYIL 293 Query: 276 PTFYVVIIFAF-VIGFTSAGGVVQIGLTLMAERF--PYAKGKATGIYYSTGSIATFTIPL 332 F AF ++ ++GG+ L M R +G+ G + S+ + PL Sbjct: 294 LAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPL 353 Query: 333 ITAHLSQRSIA---DIMWFDTAIGFLLALFI 360 + + SI W A +LL L Sbjct: 354 LFTAIYAASITTWNGWAWIAGAALYLLCLPA 384 Score = 29.8 bits (67), Expect = 0.019 Identities = 25/137 (18%), Positives = 51/137 (37%), Gaps = 3/137 (2%) Query: 20 NAAGVSIVISSLGI-GRLSVLLFAGLLSDRFGRRPFIMLGMCCYMAFFFDILQTNNIIIA 78 +A + I +++ GI L+ + G ++ R G R +MLGM + + +A Sbjct: 244 DATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMA 303 Query: 79 YVFGFLAGMANSFLDAGTYPSLMEAFPRSPGTANILIKAFVSSGQFLLPLIISLL--VWA 136 + L + A + G + A S + PL+ + + Sbjct: 304 FPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASI 363 Query: 137 ELWFGWSFMIAAGIMFI 153 W GW+++ A + + Sbjct: 364 TTWNGWAWIAGAALYLL 380
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.8 bits (67), Expect = 0.021 Identities = 31/150 (20%), Positives = 63/150 (42%), Gaps = 7/150 (4%) Query: 4 LAEKFSTDNAGIAYLISGIGLGRLISILFFGVISDKFGRRAVILMAVIMY----LLFFFG 59 +A F+ A ++ + L I +G +SD+ G + ++L +I+ ++ F G Sbjct: 40 IANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVG 99 Query: 60 IPACPNLTLAYGLAVCVGIANSALDTGGYPALMECFPKASGSAVILVKAMVSFGQMFYPM 119 L +A + A AL + G A L+ ++V+ G+ P Sbjct: 100 HSFFSLLIMARFIQGAGAAAFPALVMVVVARY--IPKENRGKAFGLIGSIVAMGEGVGP- 156 Query: 120 LVSYMLLNNIWYGYGLIIPGILFVLITLML 149 + M+ + I + Y L+IP I + + ++ Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITVPFLM 186
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 102 bits (255), Expect = 2e-25 Identities = 78/418 (18%), Positives = 172/418 (41%), Gaps = 21/418 (5%) Query: 3 SMRKHIAFASMCMGLFIAQLDIQIVSSSLNEIGGGLSAGKDEMAWLQTSYLIAEIIVIPL 62 ++R + +C+ F + L+ +++ SL +I + W+ T++++ I + Sbjct: 9 NLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAV 68 Query: 63 SGWLSRVFSTRWLFTLSAGIFTLMSIACGLAWN-IQIMILFRALQGAAGASMIPLVFTMA 121 G LS + L I S+ + + ++I+ R +QGA A+ LV + Sbjct: 69 YGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVV 128 Query: 122 FIYYQGKELGLAAAVVSALASLSPTLGPTLGGWLTDNLDWRWLFYINILPGIYLVLSIPF 181 Y + G A ++ ++ ++ +GP +GG + + W +L I ++ ++++PF Sbjct: 129 ARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMI----TIITVPF 184 Query: 182 LVNFDKPDLSLLKVADYPSIILLAMTLGCLEYTLEEGARWGWLDDNTILLTSVLALVSFI 241 L+ K ++ + D IIL+++ + +L +++++SF+ Sbjct: 185 LMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTS-YSISFL---------IVSVLSFL 234 Query: 242 LFAARTLTISNPIMDLHAFKDKNFTLGCFFSFSGGVGIFSTVYLIPVFLGQIRGLNAEEI 301 +F +++P +D K+ F +G + V ++P + + L+ EI Sbjct: 235 IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEI 294 Query: 302 GFAVCTTG-IFQLFSVPFYFWLSKKINLRWLLMAGLGGFVFSMYL--FTPITHEWGWQEL 358 G + G + + L + ++L G+ S F T W + + Sbjct: 295 GSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSW-FMTI 353 Query: 359 LFPQAIRGISQQFAMAPIVTLTLGGIPKERLKLASGVFNLTRNLGGAIGIALCGSILN 416 + + G+S F I T+ + ++ + N T L GIA+ G +L+ Sbjct: 354 IIVFVLGGLS--FTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.2 bits (68), Expect = 0.017 Identities = 10/57 (17%), Positives = 17/57 (29%), Gaps = 2/57 (3%) Query: 164 RFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRF--RLGMLVFFGMLGWALLTAMNQ 218 R L R + + + A L + P R R M ++L + Sbjct: 26 RKQLDTPVREKDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEI 82
>PF01206#SirA family protein Length = 76 Score = 92.5 bits (230), Expect = 6e-29 Identities = 16/71 (22%), Positives = 37/71 (52%) Query: 7 DYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCPQSINNIPLDARNHGYTVLDIQQ 66 D LD G CP P + + + + GE+L V++ P S+ + ++ G+ +L+ ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 67 DGPTIRYLIQK 77 + T + +++ Sbjct: 65 EDGTYHFRLKR 75
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 509 bits (1312), Expect = 0.0 Identities = 239/388 (61%), Positives = 282/388 (72%), Gaps = 33/388 (8%) Query: 1 MKKLTVAISAVAASVLMAMSAQAAEIYNKDSNKLDLYGKVNAKHYFSSNDADDGDTTYVR 60 MK+ +A+ V ++L A +A AAEIYNKD NKLDLYGKV+ HYFS + + DGD TY+R Sbjct: 1 MKRKVLAL--VIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMR 58 Query: 61 LGFKGETQINDQLTGFGQWEYEFKGNRAESQGSSKDKTRLAFAGLKFGDYGSIDYGRNYG 120 +GFKGETQINDQLTG+GQWEY + N E +G++ TRLAFAGLKFGDYGS DYGRNYG Sbjct: 59 VGFKGETQINDQLTGYGQWEYNVQANTTEGEGANS-WTRLAFAGLKFGDYGSFDYGRNYG 117 Query: 121 VAYDIGAWTDVLPEFGGDTWTQTDVFMTGRTTGVATYRNNDFFGLVDGLNFAAQYQGKND 180 V YD+ WTD+LPEFGGD++T D +MTGR GVATYRN DFFGLVDGLNFA QYQGKN+ Sbjct: 118 VLYDVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNE 177 Query: 181 R----------------TDVTEANGDGFGFSTTYEY-EGFGVGATYAKSDRTNDQVIYGN 223 D+ NGDGFG STTY+ GF GA Y SDRTN+QV G Sbjct: 178 SQSADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGG 237 Query: 224 NSLNASGQNAEVWAAGLKYDANNIYLATTYSETQNMTVFG------NNHIANKAQNFEVV 277 A G A+ W AGLKYDANNIYLAT YSET+NMT +G + +ANK QNFEV Sbjct: 238 T--IAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVT 295 Query: 278 AQYQFDFGLRPSVAYLQSKGKDLG----AWGDQDLIEYIDVGATYYFNKNMSTFVDYKIN 333 AQYQFDFGLRP+V++L SKGKDL D+DL++Y DVGATYYFNKN ST+VDYKIN Sbjct: 296 AQYQFDFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKIN 355 Query: 334 LIDKSD-FTKASGVATDDIVAVGLVYQF 360 L+D D F K +G++TDDIVA+G+VYQF Sbjct: 356 LLDDDDPFYKDAGISTDDIVALGMVYQF 383
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.017 Identities = 8/30 (26%), Positives = 16/30 (53%) Query: 176 RTKWTANKVARYLYISVSTLHRRLASEGIS 205 T+ K A L ++ +TL +++ G+S Sbjct: 447 ATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 117 bits (293), Expect = 8e-38 Identities = 102/103 (99%), Positives = 102/103 (99%) Query: 2 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTVARTQAEKFTL 61 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQT ARTQAEKFTL Sbjct: 1 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL 60 Query: 62 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 104 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV Sbjct: 61 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 338 bits (868), Expect = e-118 Identities = 117/329 (35%), Positives = 197/329 (59%), Gaps = 2/329 (0%) Query: 1 MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANVTQISNKQLTDVLAEFE 60 +S LTG K+ ILL++IG + +++VFK+LSQ E+++L+ +A + I+++ +VL EF+ Sbjct: 12 VSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFK 71 Query: 61 QEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRDTASGIETLNFMEPQSAAD 120 + + DY R +L K+LG ++A ++ + L + + E + +P + + Sbjct: 72 ELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINN-LGSALQSRPFEFVRRADPANILN 130 Query: 121 LIRDEHPQIIATILVHLRRAQAADILALFDERLRHDVMLRIATFGGVQPAALAELTEVLN 180 I+ EHPQ IA IL +L +A+ IL+ ++ +V RIA P + E+ VL Sbjct: 131 FIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLE 190 Query: 181 GLLDGQ-NLKRSKMGGVRTAAEIINLMKTQQEEAVITAVREFDGELAQKIIDEMFLFENL 239 L + + GGV EIIN+ + E+ +I ++ E D ELA++I +MF+FE++ Sbjct: 191 KKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDI 250 Query: 240 VDVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLRNMSQRAADILRDDLAKRGPVRLS 299 V +DDRSIQR+L+E+D + L ALK + P++EK +NMS+RAA +L++D+ GP R Sbjct: 251 VLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRK 310 Query: 300 QVENEQKAILLIVRRLAETGEMVIGSGED 328 VE Q+ I+ ++R+L E GE+VI G + Sbjct: 311 DVEESQQKIVSLIRKLEEQGEIVISRGGE 339
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 373 bits (958), Expect = e-135 Identities = 223/228 (97%), Positives = 226/228 (99%) Query: 1 MSDNLPWKTWTPDDLAPPPAEFVPMVESEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI 60 MSDNLPWKTWTPDDLAPP AEFVP+VE EETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI Sbjct: 1 MSDNLPWKTWTPDDLAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI 60 Query: 61 AEGRQQGHEQGYQEGLAQGLEQGLAEAKAQQAPIHARMQQLVSEFQTTLDALDSVIASRL 120 AEGRQQGH+QGYQEGLAQGLEQGLAEAK+QQAPIHARMQQLVSEFQTTLDALDSVIASRL Sbjct: 61 AEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL 120 Query: 121 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT 180 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT Sbjct: 121 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT 180 Query: 181 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV 228 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV Sbjct: 181 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV 228
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 152 bits (384), Expect = 5e-51 Identities = 112/113 (99%), Positives = 113/113 (100%) Query: 2 AEEQLKMLIDYQNEYRNNLNSDMSAGMTSNRWINYQQFIQTLEKAITQHRQQLNQWTQKV 61 AEEQLKMLIDYQNEYRNNLNSDMSAG+TSNRWINYQQFIQTLEKAITQHRQQLNQWTQKV Sbjct: 35 AEEQLKMLIDYQNEYRNNLNSDMSAGITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKV 94 Query: 62 DIALNSWREKKQRLQAWQTLQERQSTAALLAENRLDQKKMDEFAQRAAMRKPE 114 DIALNSWREKKQRLQAWQTLQERQSTAALLAENRLDQKKMDEFAQRAAMRKPE Sbjct: 95 DIALNSWREKKQRLQAWQTLQERQSTAALLAENRLDQKKMDEFAQRAAMRKPE 147
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 468 bits (1204), Expect = e-168 Identities = 364/375 (97%), Positives = 369/375 (98%) Query: 1 MIRLAPLITADVDTTTLPGGKASDAAQDFLTLLSEALAGETTTDKAAPQLLVATDKPTTK 60 MIRLAPLITADVDTTTLPGGKASDAAQDFL LLSEALAGETTTDKAAPQLLVATDKPTTK Sbjct: 1 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK 60 Query: 61 GEPLVSDILADAQQADLLIPVDETLPVINDEQSTSTPLTTAQTMTLAAVADKNTTKDEKA 120 GEPL+SDI++DAQQA+LLIPVDET PVINDEQSTSTPLTTAQTM LAAVADKNTTKDEKA Sbjct: 61 GEPLISDIVSDAQQANLLIPVDETPPVINDEQSTSTPLTTAQTMALAAVADKNTTKDEKA 120 Query: 121 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPAEKPTLFTKLTSAQLTTAQPDDAP 180 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLP EKPTLFTKLTS QLTTAQPDDAP Sbjct: 121 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAP 180 Query: 181 GTPAQPLTPLVAEAQSKAEVISTPSPVTADASPLITPHQTQPLPTVAAPVLSAPLGSHEW 240 GTPAQPLTPLVAEAQSKAEVISTPSPVTA ASPLITPHQTQPLPTVAAPVLSAPLGSHEW Sbjct: 181 GTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW 240 Query: 241 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMISPHQHVRAALEAA 300 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQM+SPHQHVRAALEAA Sbjct: 241 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAA 300 Query: 301 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVS 360 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVS Sbjct: 301 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVS 360 Query: 361 LQGRVTGNSGVDIFA 375 LQGRVTGNSGVDIFA Sbjct: 361 LQGRVTGNSGVDIFA 375
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 380 bits (977), Expect = e-134 Identities = 86/324 (26%), Positives = 148/324 (45%), Gaps = 10/324 (3%) Query: 5 ILSQAEIDALLNGDS--EVKDEPTASISGESDIRPYDPNTQRRVVRERLQALEIINERFA 62 +LSQ EID LL S + E IS I YD + +E+++ L +++E FA Sbjct: 4 VLSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHETFA 63 Query: 63 RHFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNLNLIHLKPLRGTGLVVFSPSL 122 R L LR + V ++ Y EF R++P P+ L +I + PL+G ++ PS+ Sbjct: 64 RLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVDPSI 123 Query: 123 VFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKLALEGYSDAWKAINPLEVEYVRS 182 F +D LFGG G+ KV+ R+ T E V+ ++ L ++W + L + Sbjct: 124 TFSIIDRLFGGTGQ-AAKVQ-RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRLGQI 181 Query: 183 EMQVEFTNITTSPNDIVVNTPFHVEIGNLTGEFNICLPFSMIEPLRELLVNPPLENS--R 240 E +F I P+++VV ++G G N C+P+ IEP+ L + +S R Sbjct: 182 ETNPQFAQI-VPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVRR 240 Query: 241 NEDQNWRDNLVRQVQHSQLELVANFADISLRLSQILKLKPGDVLPIEKP---DRIIAHVD 297 + + L ++ +++VA + L + IL L+ GD++ + D + + Sbjct: 241 SSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIG 300 Query: 298 GVPVLTSQYGTLNGQYALRIEHLI 321 Q G + + A +I I Sbjct: 301 NRKKFLCQPGVVGKKIAAQILERI 324
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 210 bits (537), Expect = 6e-74 Identities = 125/137 (91%), Positives = 133/137 (97%) Query: 1 MSDMNNPADDNNGAMDDLWAEALSEQKSTSEKSAADAVFQQFGGGDVSGTLQDIDLIMDI 60 MSDMNNP+D+N GA+DDLWA+AL+EQK+T+ KSAADAVFQQ GGGDVSG +QDIDLIMDI Sbjct: 1 MSDMNNPSDENTGALDDLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDI 60 Query: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV Sbjct: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 Query: 121 RITDIITPSERMRRLSR 137 RITDIITPSERMRRLSR Sbjct: 121 RITDIITPSERMRRLSR 137
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 281 bits (720), Expect = 4e-99 Identities = 203/204 (99%), Positives = 204/204 (100%) Query: 1 MQTLVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIM 60 +QTLVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIM Sbjct: 42 VQTLVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIM 101 Query: 61 SPVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQG 120 SPVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQG Sbjct: 102 SPVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQG 161 Query: 121 PEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPF 180 PEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPF Sbjct: 162 PEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPF 221 Query: 181 KLMLFVLVDGWQLLVGSLAQSFYS 204 KLMLFVLVDGWQLLVGSLAQSFYS Sbjct: 222 KLMLFVLVDGWQLLVGSLAQSFYS 245
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 67.1 bits (164), Expect = 1e-18 Identities = 22/78 (28%), Positives = 42/78 (53%) Query: 4 ESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQINEMTLSFIPKIIAVFIAII 63 + ++ G +A+ + L L+ +VA + GL++ + Q TQ+ E TL F K++ V + + Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 IAGPWMLNLLLDYVRTLF 81 + W +LL Y R + Sbjct: 62 LLSGWYGEVLLSYGRQVI 79
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 203 bits (517), Expect = 4e-67 Identities = 254/261 (97%), Positives = 257/261 (98%) Query: 1 MMQETSDQWLSWLSLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 M+Q TS+QWLSWL+LYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 Query: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPGSHL 120 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDP SHL Sbjct: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL 120 Query: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGSEPLNSNAFLAPTKAGSLIF 180 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIG EPLNSNAFLA TKAGSLIF Sbjct: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF 180 Query: 181 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC 240 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC Sbjct: 181 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC 240 Query: 241 EHLFSEIFNLLADIISELPLI 261 EHLFSEIFNLLADIISELPLI Sbjct: 241 EHLFSEIFNLLADIISELPLI 261
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 288 bits (739), Expect = 1e-98 Identities = 137/269 (50%), Positives = 165/269 (61%), Gaps = 31/269 (11%) Query: 31 DTSYARVGVKGETQINPEMTGYGQFELDLEASNRHNPDQ---TRLAYAGLSYKDFGSFDY 87 D +Y RVG KGETQIN ++TGYGQ+E +++A+ TRLA+AGL + D+GSFDY Sbjct: 53 DQTYMRVGFKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDY 112 Query: 88 SRNVGVAYDAEAFTDMFVEWGGDSWAGTDLFMTNRTNGVATYRNTDFFGMVEGLNFALQY 147 RN GV YD E +TDM E+GGDS+ D +MT R NGVATYRNTDFFG+V+GLNFALQY Sbjct: 113 GRNYGVLYDVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQY 172 Query: 148 QGKNEGTGNY----------------KANGDGHGLSATYTID-GFSFAGAYANSDRTDWQ 190 QGKNE NGDG G+S TY I GFS AY SDRT+ Q Sbjct: 173 QGKNESQSADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQ 232 Query: 191 SGDGK----GERAEVWALSTKYDANNVYAAVMYGESHNM-------NSDDGDVVNKTQNF 239 G G++A+ W KYDANN+Y A MY E+ NM DG V NKTQNF Sbjct: 233 VNAGGTIAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNF 292 Query: 240 EAVLQYQFDFGLRPSIGYSYSKALDVAGQ 268 E QYQFDFGLRP++ + SK D+ Sbjct: 293 EVTAQYQFDFGLRPAVSFLMSKGKDLTYN 321
>PF06580#Sensor histidine kinase Length = 349 Score = 35.2 bits (81), Expect = 4e-04 Identities = 38/195 (19%), Positives = 73/195 (37%), Gaps = 34/195 (17%) Query: 261 TLSQIRSIAEYQKTIAGN-IEELENISRLTENILFLARADKNNVLVKLDSLSLNKEVENL 319 L+ IR++ T A + L + R + L ++ V SL E+ + Sbjct: 178 ALNNIRALILEDPTKAREMLTSLSELMRYS-----LRYSNARQV-------SLADELTVV 225 Query: 320 LDYL--EYLSDEKEICFKVKCNQQIFADKI---LLQRMLSNLIVNAIRYSPEKSRIHITS 374 YL + E + F+ + N I ++ L+Q ++ N I + I P+ +I + Sbjct: 226 DSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKG 285 Query: 375 FLDANGSLNIDIASPGTKINEPEKLFRRFWRGDNSRHSVGQGLGLSLVKA-IAELHGGSA 433 D NG++ +++ + G+ + K G GL V+ + L+G A Sbjct: 286 TKD-NGTVTLEVENTGSLALKNTKE--------------STGTGLQNVRERLQMLYGTEA 330 Query: 434 TYHYLSKHNVFRITL 448 K + Sbjct: 331 QIKLSEKQGKVNAMV 345
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.6 bits (204), Expect = 1e-20 Identities = 30/117 (25%), Positives = 60/117 (51%), Gaps = 1/117 (0%) Query: 2 KILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGWQ 61 IL+ +D+ + + Q LS AGY + S+ D L++ D+++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 ILQTLRTA-KQTPVICLTARDSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQ 117 +L ++ A PV+ ++A+++ ++ + GA DYL KPF +EL+ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 31.4 bits (71), Expect = 0.002 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 7/66 (10%) Query: 41 TKEHLLPHFL-EHLGNNHLDI------GVGTGFYLTHVPESSLISLMDLNEASLNAASTR 93 T EHL F+ HL + ++I G TGFY++ + S + D A++ Sbjct: 54 TLEHLYAGFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKV 113 Query: 94 AGESKI 99 ++KI Sbjct: 114 ENQNKI 119
>FLAGELLIN#Flagellin signature. Length = 507 Score = 25.0 bits (54), Expect = 0.029 Identities = 14/77 (18%), Positives = 31/77 (40%), Gaps = 9/77 (11%) Query: 2 KSMDKISTGIAYGTSAGSAGYWFL--------QWLDQVSPSQWAAIGVLGSLVLGFLTYL 53 +++++S+G+ ++ A + + L Q S + I + G L + Sbjct: 26 SAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNANDGISIA-QTTEGALNEI 84 Query: 54 TNLYFKIREDKRKAARG 70 N ++RE +A G Sbjct: 85 NNNLQRVRELSVQATNG 101
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 64.1 bits (156), Expect = 5e-18 Identities = 19/46 (41%), Positives = 32/46 (69%) Query: 23 QKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFTAYEP 68 + +++ ++++CLT+++ +TRK LCE+R R G EVA F AYE Sbjct: 5 RSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYES 50
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 46.7 bits (111), Expect = 5e-08 Identities = 33/175 (18%), Positives = 64/175 (36%), Gaps = 35/175 (20%) Query: 1 MNILLFGKTGQVGWELQRALAPLGN-LIALDVHSTDY--------------------CGD 39 M L+ G G +G+ + + L G+ ++ +D + Y D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 40 FSNPEGVAETVKKIRPDVIVNAAAHTAVDKAESEP------NFAQLLNATCVEAIAKAAN 93 ++ EG+ + + + + AV + P N LN + + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLN---ILEGCRHNK 117 Query: 94 EVGAWVIHYSTDYVFPGNGDTPWLETDATA-PLNVYGETKLAGEKALQEHCAKHL 147 + +++ S+ V+ N P+ D+ P+++Y TK A E L H HL Sbjct: 118 -IQH-LLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANE--LMAHTYSHL 168
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 184 bits (469), Expect = 1e-57 Identities = 89/360 (24%), Positives = 149/360 (41%), Gaps = 48/360 (13%) Query: 1 MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLT--YAGNL-ESLADVSDSERYAFEHA 57 MK LVTG AGFIG V + ++ VV +D L Y +L ++ ++ + F Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DICDAVAMSRIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEAARNYWSA 117 D+ D M+ +FA + V V S+ P A+ ++N+ G +LE R+ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN--- 116 Query: 118 LNDEKKKSFRFHHISTDEVYGDLPHPDEANNNEALPLFTETTAYAPSSPYSASKASSDHL 177 K + S+ VYG N +P T+ + P S Y+A+K +++ + Sbjct: 117 ------KIQHLLYASSSSVYGL---------NRKMPFSTDDSVDHPVSLYAATKKANELM 161 Query: 178 VRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEGKALPIYGKGDQIRDWLYVE 237 + YGLP YGP+ P+ + LEGK++ +Y G RD+ Y++ Sbjct: 162 AHTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYID 221 Query: 238 D-------------HARALYTVVTEGKA-----GETYNIGGHNEKKNIDVVLTICDLLDE 279 D HA +TV T A YNIG + + +D + + D L Sbjct: 222 DIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALG- 280 Query: 280 IVPKEKSYREQITYVADRPGHDRRYAIDADKISRELGWKPQETFESGIRKTVEWYLANTN 339 + +K+ +PG + D + +G+ P+ T + G++ V WY Sbjct: 281 -IEAKKNMLPL------QPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDFYK 333
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.0 bits (104), Expect = 5e-07 Identities = 33/167 (19%), Positives = 64/167 (38%), Gaps = 11/167 (6%) Query: 61 ALAQTQGQLAKDKATLANARRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEAS 120 + +L K+ L ++ AK +L + L + T + Sbjct: 260 KYVEAVNELRVYKSQLEQIESEILS----AKEEYQLVTQLFKNEILDKLRQTTDNIGLLT 315 Query: 121 --VASAQLQLDWSRITAPVDGRV-GLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPE 177 +A + + S I APV +V LK G +++ +T +V++ + +++ + Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTALVQN 374 Query: 178 SDIATVVQAQKAGKPLMVEAWDRTNSKKL-SEGTLLSLDNQIDATTG 223 DI + Q A + VEA+ T L + ++LD D G Sbjct: 375 KDIGFINVGQNA--IIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLG 419 Score = 43.7 bits (103), Expect = 8e-07 Identities = 21/122 (17%), Positives = 47/122 (38%), Gaps = 13/122 (10%) Query: 15 GTITAA-NTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPSQFKVALAQTQGQLAKDK 73 G +T + + ++ + + + +EG+ V+ GD+L ++ + K + Sbjct: 88 GKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTAL-------GAEADTLKTQ 140 Query: 74 ATLANARRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRI 133 ++L AR + RYQ L+++ EL+ L E + L + Sbjct: 141 SSLLQARLEQTRYQILSRS-----IELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQF 195 Query: 134 TA 135 + Sbjct: 196 ST 197
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 905 bits (2340), Expect = 0.0 Identities = 286/1035 (27%), Positives = 502/1035 (48%), Gaps = 40/1035 (3%) Query: 6 LFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVAT 65 FI RP+ +L++ + + G L LPVA P + P + VSA+ PGA +T+ +V Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 66 PLERSLGRIAGVSEMTSSS-SLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMP 124 +E+++ I + M+S+S S GS I L F D + A VQ + A LLP + Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ 123 Query: 125 SRPTYRKANPSDAPIMILTLTSDT--YSQGELYDFASTQLAPTISQIDGVGDVDVGGSSL 182 + S + +M+ SD +Q ++ D+ ++ + T+S+++GVGDV + G+ Sbjct: 124 -QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY 182 Query: 183 PAVRVGLTPQALFNQGVSLDDVRTAISNANVRKPQG------ALEDGTHRWQIQTNDELK 236 A+R+ L L ++ DV + N + G AL I K Sbjct: 183 -AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 237 TAAEYQPLIIHYN-NGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQ 295 E+ + + N +G VRL DVA V ++ N KPA L I+ AN + Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 296 TVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRS 355 T +I+AKL ELQ P + + D +P ++ S+ EV +TL ++ LV LV++LFL++ Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 356 GRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHL- 414 RAT+IP +AVPV L+GTFA + G+S+N L++ + +A G +VDDAIVV+EN+ R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 415 EAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGIS 474 E + P +A + ++ ++ +++ L AVF+P+ GG G + R+F++T+ A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 475 LLVSLTLTPMMCGWMLKASKPREQKRLRGFG----RMLVALQQGYGKSLKWVLNHTRLVG 530 +LV+L LTP +C +LK + GF Y S+ +L T Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 531 VVLLGTIALNI----SIPKTFFPEQDTGVLMGGIQADQSISFQ----AMRGKLQDFMKII 582 ++ +A + +P +F PE+D GV + IQ + + + ++K Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 583 RD-DPAVDNVTGFT-GGSRVSSGMMFITLKPRDERS---ETAQQIIDRLRVKLAKEPGAN 637 + +V V GF+ G ++GM F++LKP +ER+ +A+ +I R +++L K Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 638 LFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATL-----PELADVNSD 692 + + I G + ++ L D + + R +L + L V + Sbjct: 662 VIPFNMPAIVELGTATGFDFE---LIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 693 QQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRY 752 ++ A+ L D++ LG+ + N ++ A G ++ K+ ++ D ++ Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 753 TQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSD 812 ++K++V + G+ +P S F + + I G S D Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 813 ASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVH 872 A A ++ ++L P+ + + G + + + N L+ + V++ L LYES+ Sbjct: 839 AMALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSI 896 Query: 873 PLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGN 932 P++++ +P VG LLA LFN + ++G++ IG+ KNAI++V+FA + Sbjct: 897 PVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG 956 Query: 933 LTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLEITIVGGLVMSQLL 992 EA A +R RPI+MT+LA + G LPL +S G GS + + I ++GG+V + LL Sbjct: 957 KGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 1016 Query: 993 TLYTTPVVYLFFDRL 1007 ++ PV ++ R Sbjct: 1017 AIFFVPVFFVVIRRC 1031 Score = 78.7 bits (194), Expect = 7e-17 Identities = 77/446 (17%), Positives = 162/446 (36%), Gaps = 26/446 (5%) Query: 588 VDNVTGFTGGS-RVSSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDI 646 +DN+ + S S + +T + + Q+ ++L++ P + Q I Sbjct: 72 IDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE----VQQQGI 127 Query: 647 RVGGRQSNASYQYTLLSDDLAALREW-----EPKIRKKLATLPELADVNSDQQDNGAE-- 699 V S+ +SD+ ++ ++ L+ L + DV GA+ Sbjct: 128 SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL----FGAQYA 183 Query: 700 MNLVYDRDTMARLGID----VQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQD 755 M + D D + + + + + + T P Q + R+ Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNP 243 Query: 756 ISALEKMFVINNEGKAIPLSYFAK--WQPANAPLSVNHQGLSAASTISFNLPTGKSLSDA 813 + +N++G + L A+ N + G AA +L D Sbjct: 244 EEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL-DT 302 Query: 814 SAAIDRAMTQL--GVPSTVRGSFA-GTAQVFQETMNSQVILIIAAIATVYIVLGILYESY 870 + AI + +L P ++ + T Q +++ V + AI V++V+ + ++ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 871 VHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRH 930 L +P +G L F + + + G++L IG++ +AI++V+ Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 931 GNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLEITIVGGLVMSQ 990 L P+EA ++ ++ + +P+ GG + + ITIV + +S Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 991 LLTLYTTPVVYLFFDRLRLRFSRKPK 1016 L+ L TP + + + K Sbjct: 483 LVALILTPALCATLLKPVSAEHHENK 508
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 125 bits (315), Expect = 2e-33 Identities = 97/429 (22%), Positives = 188/429 (43%), Gaps = 23/429 (5%) Query: 20 FMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFF 79 F L+ ++N +LP +A + P + V +++LT ++ G L+D++G++ + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 80 TAIVLFTLGSLFCALSGTLNELL-LARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTF 138 I++ GS+ + + LL +AR +QG G A + + V + +P+E A Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 139 VTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLM-LMPNYTMQTRRFDL 197 + +G +GPA+GG++ Y HW +L+ IP+ I + LM L+ FD+ Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHY--IHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 198 SGFLLLAVGMAVLTLALDGSKGTGLSPLAIAGLVAVGVVALVLYLLHARNNNRALFSLKL 257 G +L++VG+ L + + V V++ ++++ H R L Sbjct: 202 KGIILMSVGIVFFMLF---------TTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGL 252 Query: 258 FRTRTFSLGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAG-LMMIPMVLGSMGMKRI 316 + F +G+ M P ++ S G +++ P + + I Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI 312 Query: 317 VVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALL----GWYYVLPFVLFLQGMVNSTRFS 372 +V+R G VL +G++ +++ F+T + L W+ + V L G+ S + Sbjct: 313 GGILVDRRGPLYVL---NIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL--SFTKT 367 Query: 373 SMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIAGLLLGLFGSQHISVDSGTTQTVF 432 ++T+ L A +G SLL+ LS G+ I G LL + + Q+ + Sbjct: 368 VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTY 427 Query: 433 MYTWLSMAF 441 +Y+ L + F Sbjct: 428 LYSNLLLLF 436
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 31.3 bits (71), Expect = 0.009 Identities = 27/93 (29%), Positives = 34/93 (36%), Gaps = 27/93 (29%) Query: 173 LATLLAALATFLLA-------------RGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDE 219 LATL+AA A L+A V+ V H LA + P S + Sbjct: 77 LATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD---AMKCFPGSFER 133 Query: 220 L-----------GKLAQDFNQLASTLEKNQQMR 241 L G L N+LA E+ QQMR Sbjct: 134 LYCAMVAAGETSGHLDAVLNRLADYTEQRQQMR 166
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 6e-18 Identities = 28/136 (20%), Positives = 65/136 (47%), Gaps = 1/136 (0%) Query: 11 PRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLAYVRQTPPDLILLDLMLPGTDGL 70 IL+ +D+ + +L L A Y + S+ + ++ DL++ D+++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 71 TLCREIR-RFSDVPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCK 129 L I+ D+P+++++A+ + + E GA DY+ KP+ E++ + L K Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 130 PQRELQQQDAESPLII 145 + + D++ + + Sbjct: 124 RRPSKLEDDSQDGMPL 139
>LIPOLPP20#LPP20 lipoprotein precursor signature. Length = 175 Score = 26.6 bits (58), Expect = 0.026 Identities = 13/38 (34%), Positives = 24/38 (63%), Gaps = 1/38 (2%) Query: 18 EGEMKKIAAISLISIFLISGCAVHNDETSIGKFGLAYK 55 + ++KKI +S+++ +I GC+ H ++ I K AYK Sbjct: 2 KNQVKKILGMSVVAAMVIVGCS-HAPKSGISKSNKAYK 38
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 33.9 bits (77), Expect = 7e-04 Identities = 22/92 (23%), Positives = 36/92 (39%), Gaps = 2/92 (2%) Query: 156 AQGCENKNVIIIGAGT-IGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSE 214 A+G E K I GA IG + + GA + A+D + EKL S + ++ Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAH-IAAVDYNPEKLEKVVSSLKAEARHAEA 61 Query: 215 MSAPQMQSVLRELRFNQLILETAGVPQTVELA 246 A S + ++ E + V +A Sbjct: 62 FPADVRDSAAIDEITARIEREMGPIDILVNVA 93
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 26.4 bits (58), Expect = 0.029 Identities = 13/42 (30%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 6 KMLLGVLLLVTSAAWAAPATAGSTNTSGISKYE-LSSFIADF 46 ++L G LLL++S +WA ++K E L + DF Sbjct: 11 RVLTGTLLLLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDF 52
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 28.1 bits (62), Expect = 0.043 Identities = 17/79 (21%), Positives = 34/79 (43%), Gaps = 8/79 (10%) Query: 93 NITLSNNQ---SSFTSGYSVTVTPAASNAKVNISAGGGGSVMINGVATLSSA-----SSS 144 NI LS N+ + T + T++ S ++ + S G + + + + S+S Sbjct: 297 NIILSKNEDQSTQNTDSQTRTISKNTSTSRTHTSEVHGNAEVHASFFDIGGSVSAGFSNS 356 Query: 145 TRGSAAVQFLLCLLGGKSW 163 + A+ L L G ++W Sbjct: 357 NSSTVAIDHSLSLAGERTW 375
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 713 bits (1843), Expect = 0.0 Identities = 239/843 (28%), Positives = 389/843 (46%), Gaps = 35/843 (4%) Query: 2 LRMTPLASAI---VALLLGIEAYAAEETFDTHFMIGGMKDQQVANIRL--DDNQPLPGQY 56 R+ + A +AE F+ F+ Q VA++ + + PG Y Sbjct: 21 HRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADD--PQAVADLSRFENGQELPPGTY 78 Query: 57 DIDIYVNKQWRGKYEIIVKDNPQET----CLSREVIKRLGIN-----SDNFASGKQCLTF 107 +DIY+N + ++ E CL+R + +G+N N + C+ Sbjct: 79 RVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPL 138 Query: 108 EQLVQGGSYSWDIGVFRLDFSVPQAWVEELESGYVPPENWERGINAFYTSYYVSQYYSDY 167 ++ + D+G RL+ ++PQA++ GY+PPE W+ GINA +Y S Sbjct: 139 TSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQN 198 Query: 168 KASGNNKSTYVRFNSGLNLLEWQLHSDASFSKTNNNPGV-----WKSNTLYLERGFAQFL 222 + GN+ Y+ SGLN+ W+L + ++S +++ W+ +LER Sbjct: 199 RIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLR 258 Query: 223 GTLRVGDMYTSSDIFDSVRFSGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVTIEQNGF 282 L +GD YT DIFD + F G +L D MLP+S++ F P + GIA+ A VTI+QNG+ Sbjct: 259 SRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGY 318 Query: 283 VVYQKEVPPGPFAITDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQPGVSKYDF 342 +Y VPPGPF I D+ AG DL V++KEADGS + VPY++VP + + G ++Y Sbjct: 319 DIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSI 378 Query: 343 AAGRSHIEGASKQSD-FVQAGYQYGFNNLLTLYGGTMVANNYYAFTLGTGWNT-RIGAIS 400 AG A ++ F Q+ +G T+YGGT +A+ Y AF G G N +GA+S Sbjct: 379 TAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALS 438 Query: 401 VDATKSHSKQDNGDVFDGQSYQIAYNKFVSQTSTRFGLAAWRYSSRDYRTFNDHVWANNK 460 VD T+++S + DGQS + YNK ++++ T L +RYS+ Y F D ++ Sbjct: 439 VDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMN 498 Query: 461 DNYRRDENDIYDI----ADYYQNDFGRKNSFSANMSQSLPEGWGSVSLSTLWRDYWGRSG 516 ++ + + DYY + ++ ++Q L ++ LS + YWG S Sbjct: 499 GYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQTYWGTSN 557 Query: 517 SSKDYQLSYSNNWRRISYTLAASQAYGENHHE-EKRFNIFISIPCD--WGDDVTTPRRQI 573 + +Q + + I++TL+ S ++ + ++IP D + R Sbjct: 558 VDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHA 617 Query: 574 YMSNSTTFDDQGFASNNTGLSGTVGSRDQFNYGVNLSHQHQGN---ETTAGANLTWNAPV 630 S S + D G +N G+ GT+ + +Y V + G+ +T A L + Sbjct: 618 SASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGY 677 Query: 631 ATVNGSYSQSSTYRQTGASVSGGIVAWSGGVNLANRLSETFAVMNAPGIKDAYVNGQKYR 690 N YS S +Q VSGG++A + GV L L++T ++ APG KDA V Q Sbjct: 678 GNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGV 737 Query: 691 TTNRNGVVVYDGMTPYRENHLMLDVSQSDSEAELRGNRKIAAPYRGAVVLVNFDTDQRKP 750 T+ G V T YREN + LD + +L P RGA+V F + Sbjct: 738 RTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKA-RVGI 796 Query: 751 WFIKALRADGQPLTFGYEVNDIHGHNIGVVGQGSQLFIRTNEIPPSVNVAIDKQQGLSCT 810 + L + +PL FG V + G+V Q+++ + V V +++ C Sbjct: 797 KLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV 856 Query: 811 ITF 813 + Sbjct: 857 ANY 859
>INTIMIN#Intimin signature. Length = 939 Score = 28.1 bits (62), Expect = 0.015 Identities = 20/94 (21%), Positives = 32/94 (34%) Query: 36 LNGTEIAITYVYKGDKVLKQSSETKIQFASIGATTKEDAAKTLEPLSAKYKNIAGVEEKS 95 + + AITY K K K S ++ F + KT AK + KS Sbjct: 671 VANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKS 730 Query: 96 TYTDTYAQENVTIDMEKVDFKALQGISGINVSAE 129 + + V + +V+F I N+ Sbjct: 731 LVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIV 764
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 71.4 bits (175), Expect = 2e-16 Identities = 41/178 (23%), Positives = 76/178 (42%), Gaps = 14/178 (7%) Query: 2 IKVLIVDDEPLARENL-RIFLQEQSDIEIVGECSNAVEGIGAVHKLRPDVLFLDIQMPRI 60 +L+ DD+ R L + + D+ I NA + D++ D+ MP Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITS---NAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 SGLEMVGMLDPEHRPYI--VFLTAFD--EYAIKAFEEHAFDYLLKPIDEARLEKTLARLR 116 + +++ + + RP + + ++A + AIKA E+ A+DYL KP D L + R Sbjct: 61 NAFDLLPRIK-KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 117 QERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMKDVAFVSSRMSGVYVT--SHEGKE 172 E ++ L ++Q + + G S + +A + + +T S GKE Sbjct: 120 AEPKRRPSKLEDDSQDGMPLV---GRSAAMQEIYRVLARLMQTDLTLMITGESGTGKE 174
>PF06580#Sensor histidine kinase Length = 349 Score = 220 bits (562), Expect = 4e-69 Identities = 63/216 (29%), Positives = 115/216 (53%), Gaps = 3/216 (1%) Query: 343 LGEGIAQLLSAQILAGQYERQKAMLTQSEIKLLHAQVNPHFLFNALNTIKAVIRRDSEQA 402 L G + + + +M ++++ L AQ+NPHF+FNALN I+A+I D +A Sbjct: 134 LYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKA 193 Query: 403 SQLVQYLSTFFRKNLKR-PSEFVTLADEIEHVNAYLQIEKARFQSRLQVNIAIPQELSQQ 461 +++ LS R +L+ + V+LADE+ V++YLQ+ +F+ RLQ I + Sbjct: 194 REMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDV 253 Query: 462 QLPAFTLQPIVENAIKHGTSQLLDTGRVAISARREGQHLMLEIEDNAGL-YQPVTNASGL 520 Q+P +Q +VEN IKHG +QL G++ + ++ + LE+E+ L + ++G Sbjct: 254 QVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGT 313 Query: 521 GMNLVDKRLRERFGDDYGISVACEPDSYTRITLRLP 556 G+ V +RL+ +G + I ++ + + +P Sbjct: 314 GLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.9 bits (153), Expect = 7e-14 Identities = 22/114 (19%), Positives = 46/114 (40%), Gaps = 2/114 (1%) Query: 9 VMIVDDHPLMRRGVRQLLELDPGFEVVAEAGEGASAIDLANRLDIDVILLDLNMKGMSGL 68 +++ DD +R + Q L G++V A+ D D+++ D+ M + Sbjct: 6 ILVADDDAAIRTVLNQALS-RAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 69 DTLNALRRDGVTAQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAIRT 122 D L +++ +++++ + + GA YL K D L+ I Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 34.8 bits (80), Expect = 6e-05 Identities = 14/79 (17%), Positives = 32/79 (40%), Gaps = 12/79 (15%) Query: 1 MIEWQDLHHSELSVSQLYALLQLRCAVFV--------VEQNCPYQDIDGDDLTGDNRHIL 52 M+E D++H+ LS ++ L LR F + D + + ++ Sbjct: 1 MLEIFDVNHTLLSETKSGELFTLRKETFKDRLNWAVQCTDGMEFDQYDNN----NTTYLF 56 Query: 53 GWKNDELVAYARILKSDDD 71 G K++ ++ R +++ Sbjct: 57 GIKDNTVICSLRFIETKYP 75
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 32.7 bits (74), Expect = 4e-04 Identities = 49/182 (26%), Positives = 75/182 (41%), Gaps = 19/182 (10%) Query: 1 MKKKRTLFFISSL-MLLGSGTTIAGDNLHFTGNLISKSCTPVINGSQLAEVHFPAIAASD 59 MKK R L L +L S A DNL F G LI +CT Q AEV++ I + Sbjct: 1 MKKIRGLCLPVMLGAVLMSQHVHAADNLTFKGKLIIPACT-----VQNAEVNWGDIEIQN 55 Query: 60 LMNLGQSERVPLVFQLKDCHSSTLFNVKVTLTGTEDSALPGFLAFDSSSSASGAGIGIET 119 L+ G +++ + +S V +T G ++ + ++S+ASG G+ I Sbjct: 56 LVQSGGNQK-DFTVDMNCPYSLGTMKVTITSNGQTGNS----ILVPNTSTASGDGLLIYL 110 Query: 120 AAGTSVPINNTTGVTLPLNQGN---NSLNFNTWLQAKSG-----RDVTSGDFSATVTATF 171 + I N + + G + L AK G + + +G FSAT T Sbjct: 111 YNSNNSGIGNAVTLGSQVTPGKITGTAPARKITLYAKLGYKGNMQSLQAGTFSATATLVA 170 Query: 172 EY 173 Y Sbjct: 171 SY 172
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 42.8 bits (100), Expect = 8e-08 Identities = 44/171 (25%), Positives = 74/171 (43%), Gaps = 21/171 (12%) Query: 1 MKRISL---ILLWGFCSMALSNVSFHGYLVQPPNCTISNAQTIEITFQDVLIDDINGSNY 57 M R+SL +LL +A ++ G + PP CTI+N Q I + F ++ + ++ S Sbjct: 1 MIRLSLFISLLLTSVAVLADVQINIRGNVYIPP-CTINNGQNIVVDFGNINPEHVDNSRG 59 Query: 58 EQTVPYSITCDTAVRDPLMEMTLSWSGTPSDFDNAAVSSNITGLGIQLKQ---------- 107 E T SI+C +++T + G N +++NIT GI L Q Sbjct: 60 EVTKNISISCPYKSGSLWIKVTGNTMGVGQ---NNVLATNITHFGIALYQGKGMSTPLTL 116 Query: 108 ---AGQSFTINTPLVVNETDLPVLTAVPVKKSGVILPEADFEAWATLQVDY 155 +G + + L + T+VP + IL DF A++ + Y Sbjct: 117 GNGSGNGYRVTAGLDTARSTF-TFTSVPFRNGSGILNGGDFRTTASMSMIY 166
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 407 bits (1048), Expect = e-148 Identities = 251/251 (100%), Positives = 251/251 (100%) Query: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR Sbjct: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 Query: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM Sbjct: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 Query: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSWLTWPM 180 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSWLTWPM Sbjct: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSWLTWPM 180 Query: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA Sbjct: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 Query: 241 IQDDLKDIDSE 251 IQDDLKDIDSE Sbjct: 241 IQDDLKDIDSE 251
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 119 bits (300), Expect = 3e-31 Identities = 98/408 (24%), Positives = 168/408 (41%), Gaps = 25/408 (6%) Query: 19 VTIALSLATFMQMLDSTISNVAIPTISGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQ 78 + I L + +F +L+ + NV++P I+ WV T+F + +I V G+L+ Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 79 RIGELRLFLLSVTFFSLSSLMCSLS-TNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPP 137 ++G RL L + S++ + + +LI R +QG A L ++ R P Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 138 EKRTFALALWSMTVIIAPICGPILGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRE 197 E R A L V + GP +GG I W +L+ +PM I+ L L +E Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKE 192 Query: 198 TETSPVKMNLPRLTLLVLGVGGLQIMLDKGRDLDWFNSSTIIILTVVSVISLISLVIWES 257 K + ++++ VG + ML F +S I +VSV+S + V Sbjct: 193 VRI---KGHFDIKGIILMSVGIVFFML--------FTTSYSISFLIVSVLSFLIFVKHIR 241 Query: 258 TSENPILDLSLFKSRNFTIGIVSITCAYLFYSGAIVLMPQLLQKTMGYNAIWAGLAYAPI 317 +P +D L K+ F IG++ + +G + ++P +++ + G Sbjct: 242 KVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFP 301 Query: 318 GIMPLLISPLIG-----RYGNKIDMRVLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQ 372 G M ++I IG R G + + VTF +V + S T F II+ Sbjct: 302 GTMSVIIFGYIGGILVDRRGPLYVLNIGVTFL----SVSFLTASFLLETTSWFMTIIIVF 357 Query: 373 FFQGFAVACFFLPLTTISFSGLPDNKFANASSMSNFFRTLSGSVGTSL 420 G + ++TI S L + S+ NF LS G ++ Sbjct: 358 VLGGLSFTK--TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 77.2 bits (190), Expect = 1e-17 Identities = 63/419 (15%), Positives = 125/419 (29%), Gaps = 96/419 (22%) Query: 8 KKQSNRKKYFSLLVIVLFIAFSGAYAYWSMELEDMISTDDAYVT-GNADPISAQVSGSVT 66 + +R+ I+ F+ + + ++E + + + G + I + V Sbjct: 50 ETPVSRRPRLVAYFIMGFLVIAFILSVLG-QVEIVATANGKLTHSGRSKEIKPIENSIVK 108 Query: 67 VVNHKDTNYVRQGDILVSLDKTDATIALNKA----------------------------- 97 + K+ VR+GD+L+ L A K Sbjct: 109 EIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPEL 168 Query: 98 -----------------------KNNLANIVRQTNKLYLQDKQYSAEVASARIQ---YQQ 131 K + Q + L + AE + + Y+ Sbjct: 169 KLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYEN 228 Query: 132 SLEDYNRRV----PLAKQGVISKE----------TLEHTKDTLISSKAALNAAIQAYKAN 177 R+ L + I+K + S + + I + K Sbjct: 229 LSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEE 288 Query: 178 KALVMN-------TPLNR-QPQVVEAADATKEAWLVLKRTDIRSPVTGYIAQRSVQ-VGE 228 LV L + + + + + IR+PV+ + Q V G Sbjct: 289 YQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGG 348 Query: 229 TVSSGQSLMAVVPARQ-MWVNANFKETQLTDVRIGQSVNIISDLYGENVVFHGRVTGINM 287 V++ ++LM +VP + V A + + + +GQ+ I + F G + Sbjct: 349 VVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVE------AFPYTRYGYLV 402 Query: 288 GTGNAFSLLPAQNATGNWIKIVQRVPVEVSLDPKELMEH----PLRIGLSMTATIDTKD 342 G + + +V V +S++ L PL G+++TA I T Sbjct: 403 GK---VKNINLDAIEDQRLGLVFNVI--ISIEENCLSTGNKNIPLSSGMAVTAEIKTGM 456
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 49.1 bits (117), Expect = 3e-09 Identities = 22/148 (14%), Positives = 53/148 (35%), Gaps = 31/148 (20%) Query: 4 IIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETLKPDIVIIDVDIPGVNGIQV 63 ++ DD + L + ++ + + + + D+V+ DV +P N + Sbjct: 7 LVADDDAAIRTVLNQALSRAGYDVRIT-SNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 64 LETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSKKEGMNNIIAAIEAAKNGYCYF 123 L ++K + ++++SA+N + AI+A++ G + Sbjct: 66 LPRIKKARPDLPVLVMSAQNT------------------------FMTAIKASEKGAYDY 101 Query: 124 ---PFSLNRFVGSLTSDQQKLDSLSKQE 148 PF L + + L ++ Sbjct: 102 LPKPFDLTE---LIGIIGRALAEPKRRP 126
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.9 bits (197), Expect = 2e-17 Identities = 30/105 (28%), Positives = 51/105 (48%) Query: 960 SILIADDHPTNRLLLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNMDGFE 1019 +IL+ADD R +L + L+ GYDV ++ ++ DL++TDV MP+ + F+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1020 LTRKLREQNSSLPIWGLTANAQANEREKGLSCGMNLCLFKPLTLD 1064 L ++++ LP+ ++A K G L KP L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.5 bits (71), Expect = 6e-04 Identities = 15/102 (14%), Positives = 38/102 (37%), Gaps = 4/102 (3%) Query: 24 LRPWNDPEMDIERKMNHDVSLFLVAEVNGEVVG--TVMGGYDGHRGSAYYLGVHPEFRGR 81 + + D +MD+ + FL + +G + ++G + V ++R + Sbjct: 47 FKQYEDDDMDVSYVEEEGKAAFL-YYLENNCIGRIKIRSNWNG-YALIEDIAVAKDYRKK 104 Query: 82 GIANALLNRLEKKLIARGCPKIQINVPEDNDMVLGMYERLGY 123 G+ ALL++ + + + + N Y + + Sbjct: 105 GVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 29.7 bits (66), Expect = 0.014 Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 21/120 (17%) Query: 127 GNPLSSQEILEGGESLILSE-----VAEPPAQMIDSLTTLFKTIKPVKRAFICSIKENEE 181 G+ ++SQE+L +S++ + E + ++ +F+TI P+ + F +K E+ Sbjct: 217 GDTITSQELLAQAQSILNKNHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYRVKNREQ 276 Query: 182 A-QPNLLIGIEADGDIEEIIQATGSVATDTLPGDEPIDICQVKKGEKGISHFITEHIAPF 240 A + N G+ + + ++I V +KKGEK F H+ F Sbjct: 277 AYRINKKSGLNEEINNTDLISEKYYV---------------LKKGEKPYDPFDRSHLKLF 321
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 114 bits (286), Expect = 9e-30 Identities = 80/371 (21%), Positives = 143/371 (38%), Gaps = 74/371 (19%) Query: 23 GIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHS-------VGYDARTNAA 75 IDLGT N+L+ G + +E PSVV +Q VG+DA+ Sbjct: 14 SIDLGTANTLIYVKGQG----IVLNE-----PSVVAIRQDRAGSPKSVAAVGHDAK-QML 63 Query: 76 LDTANTISSVKRLMGRSLADIQQRYPHLPYQFQASENGLPMIETAAGLLNPVRVSADILK 135 T I++++ + +AD V+ +L+ Sbjct: 64 GRTPGNIAAIRPMKDGVIADF-------------------------------FVTEKMLQ 92 Query: 136 ALAARATEALAGE-LDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYG 194 + V++ VP +R+ +++A+ AG + L+ EP AAAI G Sbjct: 93 HFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAG 152 Query: 195 LDSGQEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAD 254 L + V D+GGGT +++++ L+ V +GGD FD + +Y+R Sbjct: 153 LPVSEATGSMVVDIGGGTTEVAVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYG 207 Query: 255 --IPDRSDNRVQRELLDATIAAKIALSDADSVTVNVAG---WQG-----EISREQFNELI 304 I + + R++ E+ A + + V G +G ++ + E + Sbjct: 208 SLIGEATAERIKHEI-------GSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEAL 260 Query: 305 APLVKRTLLACRRALKDAGVE-ADEVLE--VVMVGGSTRVPLVRERVGEFFGRPPLTSID 361 + + A AL+ E A ++ E +V+ GG + + + E G P + + D Sbjct: 261 QEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAED 320 Query: 362 PDKVVAIGAAI 372 P VA G Sbjct: 321 PLTCVARGGGK 331
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 27.8 bits (61), Expect = 0.019 Identities = 15/24 (62%), Positives = 18/24 (75%), Gaps = 2/24 (8%) Query: 42 RPGLK--KLLKTLSAGDTLVVWKL 63 RPGLK KLLKTL+ GDT+ +L Sbjct: 202 RPGLKDTKLLKTLAIGDTITSQEL 225
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 26.3 bits (58), Expect = 0.032 Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 11/87 (12%) Query: 4 KTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVSKIRV--GMTQQQVAYALGT 61 K + AVL + AG LER ++ Q + + + VS+ + GMT ++ A Sbjct: 69 KVV-LCGAVLARVDAGDEQLERKIH---YRQQDLVDYSPVSEKHLADGMTVGELCAA--A 122 Query: 62 PLMSDPFGTNTWFYVFRQQPGHEGVTQ 88 MSD N + G G+T Sbjct: 123 ITMSDNSAANL---LLATVGGPAGLTA 146
>PF07675#Cleaved Adhesin Length = 1358 Score = 26.2 bits (57), Expect = 0.014 Identities = 11/36 (30%), Positives = 14/36 (38%), Gaps = 1/36 (2%) Query: 31 INVDRVPEAAEALRAQG-FRQLPVVIAGDLSWSGFR 65 V PEA R QG + Q V + + FR Sbjct: 750 KTVVTAPEAIRGTRVQGTWYQKTVQLPAGTKYVAFR 785
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 28.7 bits (64), Expect = 0.014 Identities = 20/105 (19%), Positives = 35/105 (33%), Gaps = 17/105 (16%) Query: 1 MKPRQRQAAILEYLQKQGKCSVEEL-----AQYFDTTGTTIRKDLVILEHAGTVIRTYGG 55 M QR I E + + +EL ++ T T+ +D+ E + T G Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIK--ELHLVKVPTNNG 58 Query: 56 ---VVLNKEESDPPIDHKTLINTHKKELIAEAAVSFIHDGDSIIL 97 L ++ P+ K + +A V I+L Sbjct: 59 SYKYSLPADQRFNPLS-------KLKRSLMDAFVKIDSASHLIVL 96
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 377 bits (970), Expect = e-128 Identities = 125/388 (32%), Positives = 194/388 (50%), Gaps = 33/388 (8%) Query: 174 IAALAAGALS----------NALLIEQLESQNMLPGDATPFEAVKQTQMIGLSPGMTQLK 223 I A GA +I + ++ ++ ++G S M ++ Sbjct: 91 IKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIY 150 Query: 224 KEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFG 283 + + + +DL ++I+GE+GTGKELVA+A+H+ R P V +N AA+P + ESELFG Sbjct: 151 RVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFG 210 Query: 284 HVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLR 343 H KGAFTGA + +G+FE A+ GTLFLDEIG++ + Q +LLRVLQ G+ VG +R Sbjct: 211 HEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIR 270 Query: 344 VDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRL 403 DVR++AATN+DL++ + G FR DL++RL+V PL +PPLR+R +D+ L +F +Q Sbjct: 271 SDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE- 329 Query: 404 RQGLSRVVLSAGARNLLQHYSFPGNVRELEHAIHRAVVLARATRNGDEVIL-----EAQH 458 ++GL A L++ + +PGNVRELE+ + R L E+I E Sbjct: 330 KEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPD 389 Query: 459 FAFPEVTLPPPEAAAVPVVKQNLR-----------------EATEAFQRETIRQALAQNH 501 + + V++N+R + I AL Sbjct: 390 SPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATR 449 Query: 502 HNWAACARMLETDVANLHRLAKRLGLKD 529 N A +L + L + + LG+ Sbjct: 450 GNQIKAADLLGLNRNTLRKKIRELGVSV 477
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 29.8 bits (67), Expect = 0.039 Identities = 9/47 (19%), Positives = 13/47 (27%), Gaps = 2/47 (4%) Query: 4 PLFWHFSFQKALSGWIAGIGGAVGS--LYTAAAGFTVLTGAVGVSGA 48 P F+ + L GG + G GA+G Sbjct: 393 PRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSV 439
>PF07675#Cleaved Adhesin Length = 1358 Score = 30.4 bits (68), Expect = 0.021 Identities = 20/92 (21%), Positives = 39/92 (42%), Gaps = 12/92 (13%) Query: 206 ILGQTYLPRKFKTTVVIP---PQND--IDLHANDMNFVAIAENGKLVGFNLLVGGGLSIE 260 ++ +P+ T +P PQN + A+ ++VAI+++G L G + G++ Sbjct: 240 VMPYRAMPKT--NTYTLPASLPQNQASYSIQASAGSYVAISKDGVLYGTGVANASGVATV 297 Query: 261 HGNK-----KTYARTASEFGYLPLEHTLAVAE 287 + K Y + YLP+ + E Sbjct: 298 NMTKQITENGNYDVVITRSNYLPVIKQIQAGE 329
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.5 bits (79), Expect = 0.001 Identities = 27/137 (19%), Positives = 55/137 (40%), Gaps = 11/137 (8%) Query: 93 LGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTP-EHLIGLRILIGIGLGGDYSV 151 +G+ V G +SD +G +++ F ++ S + F + LI R + G G ++ Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPAL 123 Query: 152 GHTLLAEFSPRRHRGILLGAFSVVWT----VGYVLASIAGHHFISENPEAWRWLLASAAL 207 ++A + P+ +RG G + VG + + H+ W +LL + Sbjct: 124 VMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI------HWSYLLLIPMI 177 Query: 208 PALLITLLRWGTPESPR 224 + + L + R Sbjct: 178 TIITVPFLMKLLKKEVR 194
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 283 bits (726), Expect = 3e-80 Identities = 136/571 (23%), Positives = 223/571 (39%), Gaps = 122/571 (21%) Query: 33 KKVILGIILSSIYGSYGETAFA-AMLDINNIWTRDYLDLAQNRGEFRPGATNVQLMMKDG 91 KK L I ++ +Y T + A L +++ + + D A+N+G+F GATNV + K+ Sbjct: 4 KKFKLNFIALTV--AYALTPYTEAALVRDDVDYQIFRDFAENKGKFSVGATNVLVKDKNN 61 Query: 92 KIFH--FPE-LPVPDFSAVS-NKGATTSIGGAYSVTATH--------------------N 127 K P +P+ DFS V +K T I Y V H N Sbjct: 62 KDLGTALPNGIPMIDFSVVDVDKRIATLINPQYVVGVKHVSNGVSELHFGNLNGNMNNGN 121 Query: 128 GTQHHAITTQSWDQTAYKASNRVSS----------------GDFSVHRLNKFVVETTGVT 171 H ++++ + + + + D+ + RL+KFV T Sbjct: 122 AKAHRDVSSEENRYFSVEKNEYPTKLNGKTVTTEDQTQKRREDYYMPRLDKFV------T 175 Query: 172 ESADFSLSPEDAMKRYGVNYNGKEQ-IIGFRAGAGTTSTILNGKQY-------------- 216 E A S + YN + + R G+G+ G Y Sbjct: 176 EVAPIEASTASS---DAGTYNDQNKYPAFVRLGSGSQFIYKKGDNYSLILNNHEVGGNNL 232 Query: 217 -LFGQNYNPDLLSASLFNLDWKNKSYIYT--------------NRTPFKNSPIFGDSGSG 261 L G Y ++ + + ++ +N I ++ P N + GDSGS Sbjct: 233 KLVGDAYTY-GIAGTPYKVNHENNGLIGFGNSKEEHSDPKGILSQDPLTNYAVLGDSGSP 291 Query: 262 SYLYDKEQQKWVFHGVTSTVGFISSTNIAWTNYSLFNNILVNNLKKNFTNTMQLDGKKQE 321 ++YD+E+ KW+F G + +W ++++ + ++ + + K Sbjct: 292 LFVYDREKGKWLFLGSYD--FWAGYNKKSWQEWNIYKSQFTKDVLNKDSAGSLIGSKTDY 349 Query: 322 LSSIIKD-------------------------KDLSVSGGGVLTLKQDTDLGIGGLIFDK 356 S K ++ G G LTL + D G GGL F+ Sbjct: 350 SWSSNGKTSTITGGEKSLNVDLADGKDKPNHGKSVTFEGSGTLTLNNNIDQGAGGLFFEG 409 Query: 357 NQTYKVYGKDKSYKGAGIDIDNNTTVEWNVKGVAGDNLHKIGSGTLDVKIAQGN--NLKI 414 + K + ++KGAG+ + TV W V D L KIG GTL V+ N +LK+ Sbjct: 410 DYEVKGTSDNTTWKGAGVSVAEGKTVTWKVHNPQYDRLAKIGKGTLIVEGTGDNKGSLKV 469 Query: 415 GNGTVIL------SAEKAFNKIYMAGGKGTVKINAKDALSESGNGEIYFTRNGGTLDLNG 468 G+GTVIL S + AF + + G+ T+ +N + + IYF GG LDLNG Sbjct: 470 GDGTVILKQQTNGSGQHAFASVGIVSGRSTLVLNDDKQVDPNS---IYFGFRGGRLDLNG 526 Query: 469 YDQSFQKIAATDAGTTVTNSNVKQ-STLSLT 498 +F I D G + N N+ S +++T Sbjct: 527 NSLTFDHIRNIDDGARLVNHNMTNASNITIT 557
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 752 bits (1942), Expect = 0.0 Identities = 258/870 (29%), Positives = 400/870 (45%), Gaps = 115/870 (13%) Query: 45 ICLCYSQISQAGIVRSDIAYQIYRDFAENKGLFVPGANDIPVYDKDGKLVGRL--GKAPM 102 + + ++A +VR D+ YQI+RDFAENKG F GA ++ V DK+ K +G PM Sbjct: 15 VAYALTPYTEAALVRDDVDYQIFRDFAENKGKFSVGATNVLVKDKNNKDLGTALPNGIPM 74 Query: 103 ADFSSVSSN-GVATLVSPQYIVSVKH-NGGYRSVSFGN------------------GKNT 142 DFS V + +ATL++PQY+V VKH + G + FGN +N Sbjct: 75 IDFSVVDVDKRIATLINPQYVVGVKHVSNGVSELHFGNLNGNMNNGNAKAHRDVSSEENR 134 Query: 143 YSLVDRNNHPSI-----------------DFHAPRLNKLVTEVIPSAVTSEGTKANAYKY 185 Y V++N +P+ D++ PRL+K VTEV P ++ + A Y Sbjct: 135 YFSVEKNEYPTKLNGKTVTTEDQTQKRREDYYMPRLDKFVTEVAPIEASTASSDAGTYND 194 Query: 186 TERYTAFYRVGSGTQYTKDKDGNLVKVAGGYAFKTGGTTGVPLISDATIVSNPGQTYNPV 245 +Y AF R+GSG+Q+ K N + + V I P + + Sbjct: 195 QNKYPAFVRLGSGSQFIYKKGDNYSLILNNHEVGGNNLKLVGDAYTYGIAGTPYKVNHEN 254 Query: 246 NG---------------------PLPDYGAPGDSGSPLFAYDKQQKKWVIVAVLRAYAGI 284 NG PL +Y GDSGSPLF YD+++ KW+ + +AG Sbjct: 255 NGLIGFGNSKEEHSDPKGILSQDPLTNYAVLGDSGSPLFVYDREKGKWLFLGSYDFWAGY 314 Query: 285 NGAT-NWWNVIPTDYLNQVMQDDFDAPVDFVSGLGPLNWTYDKTSGTGTLSQGSKNWTMH 343 N + WN+ + + V+ D + + +W+ + + T T + S N + Sbjct: 315 NKKSWQEWNIYKSQFTKDVLNKD--SAGSLIGSKTDYSWSSNGKTSTITGGEKSLNVDLA 372 Query: 344 GQKDNDLNAGKNLVFSGQNGAIILKDSVTQGAGYLEFKDSYTVSAES-GKTWTGAGIITD 402 KD N GK++ F G +G + L +++ QGAG L F+ Y V S TW GAG+ Sbjct: 373 DGKDKP-NHGKSVTFEG-SGTLTLNNNIDQGAGGLFFEGDYEVKGTSDNTTWKGAGVSVA 430 Query: 403 KGTNVTWKVNGVAGDNLHKLGEGTLTINGTGVNPGGLKTGDGIVVLNQQADTAGNIQAFS 462 +G VTWKV+ D L K+G+GTL + GTG N G LK GDG V+L QQ + +G AF+ Sbjct: 431 EGKTVTWKVHNPQYDRLAKIGKGTLIVEGTGDNKGSLKVGDGTVILKQQTNGSGQ-HAFA 489 Query: 463 SVNLASGRPTVVLGDARQVNPDNISWGYRGGKLDLNGNAVTFTRLQAADYGAVITN-NAQ 521 SV + SGR T+VL D +QV+P++I +G+RGG+LDLNGN++TF ++ D GA + N N Sbjct: 490 SVGIVSGRSTLVLNDDKQVDPNSIYFGFRGGRLDLNGNSLTFDHIRNIDDGARLVNHNMT 549 Query: 522 QKSQLLLDLKAQDT--------NVSEPTIGNISPFGGTGTPGNLYSMILNSQTRFYILKS 573 S + + ++ T N+ P N F G LY + L + T + + K Sbjct: 550 NASNITITGESLITDPNTITPYNIDAPDEDNPYAFRRIKDGGQLY-LNLENYTYYALRKG 608 Query: 574 ASYGNTLWGNSLNDPAQWEFVGMNKNKAVQTVKDRILAGRAKQPVIF----HGQLTGNMD 629 AS + L NS W ++G ++A + V + I R + G+ GN++ Sbjct: 609 ASTRSELPKNSGESNENWLYMGKTSDEAKRNVMNHINNERMNGFNGYFGEEEGKNNGNLN 668 Query: 630 VAIPQVPGGRKVIFDGSVNLPEGTLSQDSGTLIFQGHPVIHA-SISGSAPVSLN------ 682 V + + G NL G L+ + GTL G P HA I+G + + Sbjct: 669 VTFKGKSEQNRFLLTGGTNL-NGDLTVEKGTLFLSGRPTPHARDIAGISSTKKDPHFAEN 727 Query: 683 -----QKDWENRQFTMKTLSLK-DADFHLSRN-ASLNSDIKSDNS---HITLGSDRAFVD 732 + DW NR F T+++ +A + RN A++ S+I + N HI + Sbjct: 728 NEVVVEDDWINRNFKATTMNVTGNASLYSGRNVANITSNITASNKAQVHIGYKTGDTVCV 787 Query: 733 KNDGTGNYVIPEEGTSVPDTVNDR-------SQYEGNITLNHNSALDIGSR--FTGGIDA 783 ++D TG T D ++D+ + GN+ L ++ +G F Sbjct: 788 RSDYTGY------VTCTTDKLSDKALNSFNPTNLRGNVNLTESANFVLGKANLFGTIQSR 841 Query: 784 YDSAVSITSPDVLLTAPGAFAGSSLTVHDG 813 +S V +T + G L + +G Sbjct: 842 GNSQVRLTE-NSHWHLTGNSDVHQLDLANG 870 Score = 78.6 bits (193), Expect = 1e-16 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 18/154 (11%) Query: 865 DNAALEITRGAHASGDIHASAASTVTIGSDTPAELASAETAASAFAG--------SLLEG 916 + A + I + + + VT +D ++ A + G + + G Sbjct: 771 NKAQVHIGYKTGDTVCVRSDYTGYVTCTTDKLSDKALNSFNPTNLRGNVNLTESANFVLG 830 Query: 917 YNAAFNGAITGGRADVSM-HNALWTLGGDSAIHSLTVRNSRI------SSEGDRTFRTLT 969 F + G + V + N+ W L G+S +H L + N I +S + TLT Sbjct: 831 KANLFGTIQSRGNSQVRLTENSHWHLTGNSDVHQLDLANGHIHLNSADNSNNVTKYNTLT 890 Query: 970 VNKLDATGSDFVLRTDLKN--ADKINVTEKATGS 1001 VN L GS + L TDL N DK+ VT+ ATG+ Sbjct: 891 VNSLSGNGSFYYL-TDLSNKQGDKVVVTKSATGN 923
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 43.1 bits (101), Expect = 6e-06 Identities = 124/629 (19%), Positives = 199/629 (31%), Gaps = 75/629 (11%) Query: 311 QNTGGALVTSTAATVTGTNRLGAFSVVEGKADNVVLENGGRLDVLTGHTATNTRVDDGGT 370 ++ + V VT GA + V + + +GG + G A + Sbjct: 194 EDLPPSRVVLRDTNVTAVPASGAPAAVSVLGASELTLDGGH--ITGGRAAGVAAMQGAVV 251 Query: 371 LDVRNGGTATTVSMGNGGVLLADSGAAVSGTRSDGKAFSIGGGQA----DALMLEKGSSF 426 R G A G AV G G + G +E S Sbjct: 252 HLQRATIRRGDAPAGGAVPGGAVPGGAVPGGFGPGGFGPVLDGWYGVDVSGSSVELAQSI 311 Query: 427 TLNAGDTATDTTVNGGLFTARGGTLAGTTTLNNGAILTLSGKTV---NNDTLTIR-EGDA 482 A G T GG+L+ G ++ G L+I + A Sbjct: 312 VEAPELGAAIRVGRGARVTVSGGSLSAPH----GNVIETGGARRFAPQAAPLSITLQAGA 367 Query: 483 LLQGGALTGNGSVEKSGSGTLTVSNTTLTQKAVNLNEGTLTLNDSTVTTDVIAQRGTALK 542 QG AL E LT++ Q + E S DV Sbjct: 368 HAQGKALLYRVLPEPV---KLTLTGGADAQGDIVATELPSIPGTSIGPLDVALASQARWT 424 Query: 543 LTGSTVLNGAIDPTNVTLASGATWNIPDNATVQSVVDDLSHAGQIHF-TSTRTGKFVPAT 601 GA + ATW + DN+ V ++ L+ G + F G+F Sbjct: 425 --------GATRAVDSLSIDNATWVMTDNSNVGAL--RLASDGSVDFQQPAEAGRF--KV 472 Query: 602 LKVKNLNGQNGTISLRVRPDMAQNNADRLVIDGGRATGKTILNLVNAGNSASGLATSGKG 661 L V L G +G + V D+ + D+LV+ A+G+ L + N+G+ + T Sbjct: 473 LTVNTLAG-SGLFRMNVFADLGLS--DKLVVMQD-ASGQHRLWVRNSGSEPASANTL--- 525 Query: 662 IQVVEAINGATTEEGAFIQGNKLQAGAFNYSLNRDSDESWYLRSENAYRAEVPLYASMLT 721 + V + A T A + K+ G + Y L + + W L A A P Sbjct: 526 LLVQTPLGSAATFTLAN-KDGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQ 584 Query: 722 QAMDYDRILAGSRSHQTGVSGENNSVRLSIQGGHLGHDNNGGIARG-----------ATP 770 + + ++ G +G + A P Sbjct: 585 PPQPPQPQPEAPAPQPPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRLNP 644 Query: 771 ESSGSYG--FVRLE------GDLLRTEVAG--------MSVTAGVYGAAGHSSVDVKDDD 814 ++ G++G F + + G +VAG ++V G + G + D Sbjct: 645 DAGGAWGRGFAQRQQLDNRAGRRFDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDRG 704 Query: 815 GSRAGTVRDDAGSLGGYLNLIHNASGLWADIVAQGTRH-------SMKASSDNNDFRVRG 867 + G D+ +GGY I + SG + D + +R + +R G Sbjct: 705 FTGDGGGHTDSVHVGGYATYIAD-SGFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHG 763 Query: 868 WGWLGSLETGLPFSITDNLMLEPQLQYTW 896 G SLE G F+ D LEPQ + Sbjct: 764 VGA--SLEAGRRFTHADGWFLEPQAELAV 790
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 73.4 bits (180), Expect = 2e-15 Identities = 69/313 (22%), Positives = 109/313 (34%), Gaps = 77/313 (24%) Query: 388 IMGHVDHGKTSLLDYI-----RSTKVASGEAG-------------GITQHIGAYHVETEN 429 ++ HVD GKT+L + + T++ S + G GIT G + EN Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 430 GMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAV 489 + +DTPGH F + R D +L+++A DGV QT + +P + + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 490 NKIDKPEADPDRV----KNELSQYGI-----------------LPEEWG----------- 517 NKID+ D V K +LS + E+W Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 518 ---------------GESQFV---------HVSAKAGTGIDELLDAILLQAEVLELKAVR 553 ES H SAK GID L++ I + Sbjct: 188 KYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT--NKFYSSTHRG 245 Query: 554 KGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVL-CGFEYGRVRAMRNELGQEVLEA 612 + G V + + R +A + + G LH D V E ++ M + E+ + Sbjct: 246 QSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSINGELCKI 305 Query: 613 GPSIPVEILGLSG 625 + EI+ L Sbjct: 306 DKAYSGEIVILQN 318
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 39.7 bits (92), Expect = 2e-05 Identities = 41/160 (25%), Positives = 68/160 (42%), Gaps = 14/160 (8%) Query: 134 GHLLSQPFNSSTSVLYYNKDAFKKAGLDPEQPPKTWQDLADYSAKLKASGIKCGYASGWQ 193 G L++ P L YNKD L P PPKTW+++ +LKA G + + Sbjct: 127 GKLIAYPIAVEALSLIYNKD------LLP-NPPKTWEEIPALDKELKAKGKSALMFNLQE 179 Query: 194 GWIQLENFSAWNGLPFASKNNGFDGTDAVLEF--NKPEQVKHIAMLEEMNKKGDFSYVGR 251 + +A G F +N +D D ++ K + +++ + D Y Sbjct: 180 PYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDY--- 236 Query: 252 KDESTEKFYNGDCAMTTASSGSLANIREYAKFNYGVGMMP 291 + F G+ AMT + +NI + +K NYGV ++P Sbjct: 237 -SIAEAAFNKGETAMTINGPWAWSNI-DTSKVNYGVTVLP 274
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 50.8 bits (121), Expect = 9e-09 Identities = 36/181 (19%), Positives = 60/181 (33%), Gaps = 13/181 (7%) Query: 19 EQTPEKETEVQNEQPVVEEI---VQAQEPAKASEQAVEEQPQAHTEAEAETFAADVVEVT 75 TP + TE E E Q+ + + Q E +A + +A T EV Sbjct: 1030 PATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTN---EVA 1086 Query: 76 EQVVESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEEVSPEEWQAEAETV 135 + E+++ Q + V +E V E+ + +VSP++ Q+E Sbjct: 1087 QSGSETKETQTTE--TKETATVEKEEKAKVETEKTQ---EVPKVTSQVSPKQEQSETVQP 1141 Query: 136 EIVEAAEEEAAK--EEITDEELEAQALAAEAAEEAVMVVPPAEEEQPVAEIAQEQEKPTK 193 + A E + +E + A E + V P E V E P Sbjct: 1142 QAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPEN 1201 Query: 194 E 194 Sbjct: 1202 T 1202 Score = 47.4 bits (112), Expect = 1e-07 Identities = 40/192 (20%), Positives = 69/192 (35%), Gaps = 26/192 (13%) Query: 20 QTPEK-ETEVQNEQPVVEEIVQAQE----------PAKASEQAVEEQPQAHTEAE----- 63 TP + +V + EEI + E P++ +E E Q E Sbjct: 998 TTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQD 1057 Query: 64 AETFAADVVEVTEQVVESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEEV 123 A A EV ++ + KA + VAQ +ET + E V EE Sbjct: 1058 ATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKET------QTTETKETATVEKEEK 1111 Query: 124 SPEEWQAEAETVEIVEAAEEEAAKEEITDEELEAQALAAEAAEEAVMVVPPAEEEQPVAE 183 + E +T E+ + + + K+E E ++ QA A + V + P + A+ Sbjct: 1112 AKVE---TEKTQEVPKVTSQVSPKQE-QSETVQPQAEPARENDPTVNIKEPQSQTNTTAD 1167 Query: 184 IAQEQEKPTKEG 195 Q ++ + Sbjct: 1168 TEQPAKETSSNV 1179 Score = 46.2 bits (109), Expect = 3e-07 Identities = 36/177 (20%), Positives = 60/177 (33%), Gaps = 18/177 (10%) Query: 22 PEKETE---VQNEQPVVEEIVQAQEPAKASEQAVEEQPQAHTEAEAETFAADVVEVTEQV 78 PE E V +QA P+ S + A E TE V Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVD--EAPVPPPAPATPSETTETV 1040 Query: 79 VESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEEVSPEEWQAEAETVEIV 138 E+ K + + + + + + + + EV+ Q+ +ET E Sbjct: 1041 AENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVA----QSGSETKETQ 1096 Query: 139 EAAEEEAAKEEITDEELEAQALAAEAAEEAVMV--VPP----AEEEQPVAEIAQEQE 189 +E A E +E +A+ + E + V P +E QP AE A+E + Sbjct: 1097 TTETKETATVE---KEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREND 1150 Score = 45.1 bits (106), Expect = 6e-07 Identities = 26/159 (16%), Positives = 48/159 (30%), Gaps = 7/159 (4%) Query: 17 QKEQTPEKETEVQNEQPVVEEIVQAQEPAKASE------QAVEEQPQAHTEAEAETFAAD 70 Q +T E T + E+ VE + P S+ Q+ QPQA E + Sbjct: 1096 QTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNI 1155 Query: 71 VVEVTEQVVESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEEVSPEEWQA 130 ++ ++ QP E + E V E+ V + PE+ P Sbjct: 1156 KEPQSQTNTTADTEQPAKETSSNVEQPVTES-TTVNTGNSVVENPENTTPATTQPTVNSE 1214 Query: 131 EAETVEIVEAAEEEAAKEEITDEELEAQALAAEAAEEAV 169 + + + + + + A + Sbjct: 1215 SSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLT 1253 Score = 38.5 bits (89), Expect = 7e-05 Identities = 27/177 (15%), Positives = 52/177 (29%), Gaps = 12/177 (6%) Query: 17 QKEQTPEKETEVQNEQPVVEEIVQAQEPAKASEQAVEEQPQAHTEAEAETFAAD------ 70 +E E ++ V+ E E + +E + E + Sbjct: 1065 NREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE-TATVEKEEKAKVETEKTQEVP 1123 Query: 71 --VVEVTEQVVESEKAQPEAEVVAQPEPVV--EETPEPVAIEREELPLPEDVNAEEVSPE 126 +V+ + +SE QP+AE + +P V +E + ++ ++ P Sbjct: 1124 KVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPV 1183 Query: 127 EWQAEAETV-EIVEAAEEEAAKEEITDEELEAQALAAEAAEEAVMVVPPAEEEQPVA 182 T +VE E E+ +V VP E + Sbjct: 1184 TESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTS 1240
>SHIGARICIN#Ribosome inactivating protein family signature. Length = 289 Score = 25.9 bits (57), Expect = 0.039 Identities = 6/21 (28%), Positives = 13/21 (61%) Query: 7 FFIVIIGLIVVAASFRFMQQR 27 +V+I AA ++F++Q+ Sbjct: 173 ALMVLIQSTSEAARYKFIEQQ 193
>PF01206#SirA family protein Length = 76 Score = 105 bits (265), Expect = 3e-34 Identities = 24/72 (33%), Positives = 41/72 (56%) Query: 9 DHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKET 68 D +LDA GL CP P++ +KT+ M GE L ++A DP + +D F HEL+ ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 69 DGLPYRYLIRKG 80 + Y + +++ Sbjct: 65 EDGTYHFRLKRA 76
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 55.2 bits (133), Expect = 2e-10 Identities = 80/398 (20%), Positives = 147/398 (36%), Gaps = 32/398 (8%) Query: 27 LRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHDVM--GFSAFWAGLVISLQYFATLLSR 84 ++ N ++ I+ + IGL + VLPG + D++ G++++L Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 85 PHAGRYADLLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRVILGI-GQS 143 P G +D G + +++ L G + + Y L V L +GR++ GI G + Sbjct: 61 PVLGALSDRFGRRPVLLVSLAG---AAVDYAIMATAPFLWV-----LYIGRIVAGITGAT 112 Query: 144 FAGTGSTLWGVGVVGSL--HIGRVISWNGIVTYGAMAMGAPLGVVFYHWGGLQALALIIM 201 A G+ + + H G + + G +G +G H A AL + Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGL 172 Query: 202 GVALVAILLAIPRPTVK--ASKGKPLPFRAVLGRVWLYGMALALA-----SAGFGVIATF 254 LL + + P + + +A +A V A Sbjct: 173 NFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAAL 232 Query: 255 ITLFYDAK-GWDGAAFALTLFSCAFVGT---RLLFPNGINRIGGLNVAMICFSVEIIGLL 310 +F + + WD ++L + + + ++ R+G M+ + G + Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI 292 Query: 311 LVGVATMPWMAKIG-VLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGV 369 L+ AT WMA VLLA G + PAL + + V ++ QG + L+ + Sbjct: 293 LLAFATRGWMAFPIMVLLASGGIGM--PALQAMLSRQVDEERQGQLQGSLAALTSLT-SI 349 Query: 370 TGPLAGLVMSWAGVPV----IYLAAAGLVAIALLLTWR 403 GPL + A + ++A A L + L R Sbjct: 350 VGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.4 bits (66), Expect = 0.018 Identities = 10/34 (29%), Positives = 19/34 (55%) Query: 25 QAVLNNVSLTLKSGETVALLGRSGCGKSTLARLL 58 Q + ++ +++ T+ + G SG GK +AR L Sbjct: 147 QEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 49.9 bits (119), Expect = 5e-09 Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 7/171 (4%) Query: 200 REREHGTVEHLLVMPITPFEIMMAKI-WSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPL 258 R T E +L + +I++ ++ W+ L +G+ +V G + L Sbjct: 93 RMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGY----TQWLSLL 148 Query: 259 FMLGV-ALSLFATTSIGIFMGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQD 317 + L V AL+ A S+G+ + +A S LV+ P+ LSG P + +P + Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 318 IMLTMPTTHFVSLAQAILYRGAGFEIVWPQFLTLMAIGGAFF-TIALLRFR 367 +P +H + L + I+ ++ + I FF + ALLR R Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTALLRRR 259
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.045 Identities = 9/26 (34%), Positives = 14/26 (53%) Query: 37 ARCMVGLIGPDGVGKSSLLSLISGAR 62 V L G G+GKS+L++ + G Sbjct: 595 FDYSVVLEGTGGIGKSTLINTLVGLD 620
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 84.5 bits (209), Expect = 4e-20 Identities = 71/408 (17%), Positives = 139/408 (34%), Gaps = 81/408 (19%) Query: 6 RHLAWWVVGALAVAAVVAWWLLRPAGVP-EGFAVSNGRIEATEVDIASKIAGRIDTILVK 64 R +A++++G L +A +++ G +GR + I + I+VK Sbjct: 58 RLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKE----IKPIENSIVKEIIVK 113 Query: 65 EGQFVREGEVLAKMDTRV----------------LQEQRLEAI----------------- 91 EG+ VR+G+VL K+ L++ R + + Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 92 -------------------AQIKEAQSAVAAAQALLEQRQSETRAAQSLVNQRQAELDSV 132 Q Q+ + L+++++E + +N+ + Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 133 AKRHTRSRSLAQRGAISAQQLDDDRAAAESARAALESAKAQVSASKAAIEAARTNIIQ-- 190 R SL + AI+ + + A L K+Q+ ++ I +A+ Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 191 -----------AQTRVEAAQATERRIAADID--DSELKAPRDGRV-QYRVAEPGEVLAAG 236 QT T + S ++AP +V Q +V G V+ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 237 GRVLNMVDLSDVY-MTFFLPTEQAGTLKLGGEARLILDAAPDLRIPATISFVASVAQFTP 295 ++ +V D +T + + G + +G A + ++A P R V V Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYG---YLVGKVKNINL 410 Query: 296 KTVETSDERLKLMFRVKARIPPELLQQHLEYV--KTGLPGVAWVRVNE 341 +E D+RL L+F V I L + + +G+ A ++ Sbjct: 411 DAIE--DQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGM 456
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 264 bits (675), Expect = 9e-83 Identities = 106/409 (25%), Positives = 176/409 (43%), Gaps = 35/409 (8%) Query: 2 SITTNRYAS-GYATLTEAVSAQDERNRKRDKNSHDGS------------------TISLS 42 + RY++ GY + ++ ++ ++++ Sbjct: 475 QLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVT 534 Query: 43 QPLGNIGNLNFNTTRYNSSRGTGNTRSTSLSYSTVWRGITFSINWAKNDLLTSHKWKVDR 102 Q LG L + + + +T + I ++++++ D+ Sbjct: 535 QQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGR--DQ 592 Query: 103 KLSVGISVPLSLG-------DENQIYASSQMSRSGEQGNNYQVSLSGQ--NSGGVWWDVA 153 L++ +++P S AS MS + G + + V Sbjct: 593 MLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQ 652 Query: 154 TNITNAHQSQPKSTMNIVQVGKNGSYGQFSSHYSSSENMKQLGANLSGGILITRDGLTFG 213 T ST + G YG + YS S+++KQL +SGG+L +G+T G Sbjct: 653 TGYAGGGDGNSGSTGY-ATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLG 711 Query: 214 QNVDGTLALIEAPGATGVNVNGWPGLSTDFRGYAILP-VQPYRRDDVILDEKTIGKNYDL 272 Q ++ T+ L++APGA V G+ TD+RGYA+LP YR + V LD T+ N DL Sbjct: 712 QPLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDL 771 Query: 273 PQTSQLVVPTAGAVVPATLAVKSGDKGLVTLKQKEGKPIPFGAVISYSKDTENMAGIVGE 332 VVPT GA+V A + G K L+TL KP+PFGA+++ +GIV + Sbjct: 772 DNAVANVVPTRGAIVRAEFKARVGIKLLMTLTH-NNKPLPFGAMVTSESSQS--SGIVAD 828 Query: 333 DGIAYVSGLSAEGEFNVKWGYSKDQSCIAKYQLPAKKSASGLYQIAATC 381 +G Y+SG+ G+ VKWG ++ C+A YQLP + L Q++A C Sbjct: 829 NGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAEC 877
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 296 bits (758), Expect = e-101 Identities = 137/268 (51%), Positives = 165/268 (61%), Gaps = 31/268 (11%) Query: 31 DTSYARVGVKGETQINPEMTGYGQFELDLEASNRHNPDQ---TRLAYAGLSYKDFGSFDY 87 D +Y RVG KGETQIN ++TGYGQ+E +++A+ TRLA+AGL + D+GSFDY Sbjct: 53 DQTYMRVGFKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDY 112 Query: 88 SRNVGVAYDAEAFTDMFVEWGGDSWAGTDLFMTNRTNGVATYRNTDFFGMVEGLNFALQY 147 RN GV YD E +TDM E+GGDS+ D +MT R NGVATYRNTDFFG+V+GLNFALQY Sbjct: 113 GRNYGVLYDVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQY 172 Query: 148 QGKNEGTGNY----------------KANGDGHGLSATYTID-GFSFAGAYANSDRTDWQ 190 QGKNE NGDG G+S TY I GFS AY SDRT+ Q Sbjct: 173 QGKNESQSADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQ 232 Query: 191 SGDGK----GERAEVWALSTKYDANNVYAAVMYGESHNM-------NSDDGDVVNKTQNF 239 G G++A+ W KYDANN+Y A MY E+ NM DG V NKTQNF Sbjct: 233 VNAGGTIAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNF 292 Query: 240 EAVLQYQFDFGLRPSIGYSYSKALDVAG 267 E QYQFDFGLRP++ + SK D+ Sbjct: 293 EVTAQYQFDFGLRPAVSFLMSKGKDLTY 320
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 27.5 bits (61), Expect = 0.017 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 1/66 (1%) Query: 77 MTCLTVFIISVALLMVGLWNATLLLSEKGFYGLAFFLSLFGAVAVQKNIRDAGINPPKET 136 MT T II LL L + + GLA FL+ F V I P E Sbjct: 61 MTSFTRIIIVFGLLRNALGTPSAP-PNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEE 119 Query: 137 QVTQEE 142 +++ +E Sbjct: 120 KISMQE 125
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 63.0 bits (152), Expect = 5e-13 Identities = 52/146 (35%), Positives = 86/146 (58%), Gaps = 3/146 (2%) Query: 153 GRYSKALGKLSIAMGDSSKAEGANAIALGRSSVASGTDSLAFGRQSLASAANAIAIGAET 212 G + A G SIA+G +++A A+A+G S+A+G +S+A G S A +A+ GA + Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAAS 121 Query: 213 EAAENATAIGNNAKAKGTNSMAMGFGSLADKVNTIALGNGSQALADN--AIAIGQGNKAD 270 A ++ AIG A T +A+GF S AD N++A+G+ S A++ +IAIG +K D Sbjct: 122 TAQKDGVAIGARASTSDT-GVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKTD 180 Query: 271 GVDAIALGNGSQSRGLNTIALGTASN 296 +++++G+ S +R L +A GT Sbjct: 181 RENSVSIGHESLNRQLTHLAAGTKDT 206 Score = 53.0 bits (126), Expect = 8e-10 Identities = 56/158 (35%), Positives = 87/158 (55%), Gaps = 21/158 (13%) Query: 222 GNNAKAKGTNSMAMGFGSLADKVNTIALGNGSQALADNAIAIGQGNKADGVDAIALGNGS 281 G NA AKG +S+A+G + A K +A+G GS A N++AIG +KA G A+ G S Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAAS 121 Query: 282 QSRGLNTIALGTASNATGDKSLALGSNSSANGINSVALGAD----------------SIA 325 ++ + +A+G A +T D +A+G NS A+ NSVA+G S Sbjct: 122 TAQK-DGVAIG-ARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKT 179 Query: 326 DLDNTVSVGNSSLKRKIVNVKNGAIKSDSYDAINGSQL 363 D +N+VS+G+ SL R++ ++ G + DA+N +QL Sbjct: 180 DRENSVSIGHESLNRQLTHLAAG---TKDTDAVNVAQL 214 Score = 48.4 bits (114), Expect = 3e-08 Identities = 64/214 (29%), Positives = 102/214 (47%), Gaps = 24/214 (11%) Query: 97 GYDAIAEGQYSSAIGSKTHAIGGASMAFGVSAISEGDRSIALGASSYSLGQYSMALGRYS 156 G +A A+G +S AIG+ A GA ++A+GA S + G S+A+G S Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGA--------------AVAVGAGSIATGVNSVAIGPLS 107 Query: 157 KALGKLSIAMGDSSKAEGANAIALGRSSVASGTDSLAFGRQSLASAANAIAIGAETEAAE 216 KALG ++ G +S A+ + +A+G + S T +A G S A A N++AIG + A Sbjct: 108 KALGDSAVTYGAASTAQ-KDGVAIGARASTSDT-GVAVGFNSKADAKNSVAIGHSSHVAA 165 Query: 217 N---ATAIGNNAKAKGTNSMAMGFGSLADKVNTIALGNGSQALADNA-----IAIGQGNK 268 N + AIG+ +K NS+++G SL ++ +A G + A I Q N Sbjct: 166 NHGYSIAIGDRSKTDRENSVSIGHESLNRQLTHLAAGTKDTDAVNVAQLKKEIEKTQENT 225 Query: 269 ADGVDAIALGNGSQSRGLNTIALGTASNATGDKS 302 + + + ++ LG A+N T KS Sbjct: 226 NKRSAELLANANAYADNKSSSVLGIANNYTDSKS 259 Score = 40.7 bits (94), Expect = 7e-06 Identities = 49/160 (30%), Positives = 82/160 (51%), Gaps = 9/160 (5%) Query: 75 VAIGKGAKANTFMNTSGSSTAVGYDAIAEGQYSSAIGSKTHAIGGASMAFGVSAISEGDR 134 +AIG A+A G++ AVG +IA G S AIG + A+G +++ +G ++ ++ D Sbjct: 73 IAIGATAEA-----AKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAASTAQKD- 126 Query: 135 SIALGASSYSLGQYSMALGRYSKALGKLSIAMGDSS--KAEGANAIALGRSSVASGTDSL 192 +A+GA + S +A+G SKA K S+A+G SS A +IA+G S +S+ Sbjct: 127 GVAIGARA-STSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKTDRENSV 185 Query: 193 AFGRQSLASAANAIAIGAETEAAENATAIGNNAKAKGTNS 232 + G +SL +A G + A N + + N+ Sbjct: 186 SIGHESLNRQLTHLAAGTKDTDAVNVAQLKKEIEKTQENT 225
>PF03895#Serum resistance protein DsrA. Length = 79 Score = 67.2 bits (164), Expect = 6e-16 Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 2/79 (2%) Query: 913 ESKLSGGIASAMAMTGLPQAYTPGASMASIGGGTYNGESAVALGV-SMVSANGRWVYKLQ 971 +L G+A+ A++ L Q G + S G Y ++A+A+GV S ++ + Sbjct: 2 SKELQTGLANQSALSMLVQPNGVGKTSVSAAVGGYRDKTALAIGVGSRITDRFTAKAGVA 61 Query: 972 GSTNSQGEYSAALGAGIQW 990 +T + G S G ++ Sbjct: 62 FNTYN-GGMSYGASVGYEF 79
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 104 bits (260), Expect = 7e-28 Identities = 77/348 (22%), Positives = 127/348 (36%), Gaps = 67/348 (19%) Query: 2 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKD--------------GTKFVNLVDLDI 47 +VTG AGFIG ++ K L + G ++ +DNL D +D+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 48 ADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSK-------EL 100 AD + + + A F E +F + +Y ++N + Y+ + Sbjct: 62 ADR----EGMTDLFASGHF---ERVFISPHRLAV-----RYSLENPHAYADSNLTGFLNI 109 Query: 101 LHYCLEREIP-FLYASSAATYGGRTSD-FIESREYEKPLNVYGYSKFLFDEYVRQILPEA 158 L C +I LYASS++ YG F + P+++Y +K + Sbjct: 110 LEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLY 169 Query: 159 NSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA 218 G R+F VYGP + MA F + G+S ++ KRDF Y+ D+A Sbjct: 170 GLPATGLRFFTVYGPWG--RPDMA--LFKFTKAMLEGKSIDVY-NYGKMKRDFTYIDDIA 224 Query: 219 DVNL------------WFLENGVSG-------IFNLGTGRAESFQAVADATLAY-HKKGQ 258 + + W +E G ++N+G A + + Sbjct: 225 EAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAK 284 Query: 259 IEYIPFPDKLKGRYQAFTQADLTNLRAA-GYDKPFKTVAEGVTEYMAW 305 +P G T AD L G+ P TV +GV ++ W Sbjct: 285 KNMLPLQ---PGDVL-ETSADTKALYEVIGF-TPETTVKDGVKNFVNW 327
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 32.2 bits (73), Expect = 0.003 Identities = 25/117 (21%), Positives = 45/117 (38%), Gaps = 10/117 (8%) Query: 60 HVFTDYISDKDKLYFSDL-------AKQYNSRINIYVINCDKLKSLPSTKNWTYATYFRF 112 H+ D +DKL +D+ ++ N I + S+ T+ +F Sbjct: 860 HIIDDDGGKEDKLSLADIDFRDVAFKREGNDLIMYKGEG--NVLSIGHKNGITFRNWFEK 917 Query: 113 IIADYFYHKHEKILYLDADIACKGSIKELLDYQFSTNEIAAVVAERDIEWWQNRASV 169 D H+ E+I I S+K+ L+YQ N A+ V D + ++ + Sbjct: 918 ESGDISNHEIEQIFDKSGRIITPDSLKKALEYQ-QRNNKASYVYGNDALAYGSQGDL 973
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 26.3 bits (58), Expect = 0.024 Identities = 15/80 (18%), Positives = 27/80 (33%), Gaps = 6/80 (7%) Query: 17 PEFRNEALKLAERIGVAAAARELSLYESQLYAWRSKQQQ-----QMSSSERESELAAENV 71 PE + + + R SL + Q W++++ Q +ER + LA N Sbjct: 166 PELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARIN- 224 Query: 72 RLKRQLAEQAEELSILQKAA 91 R + + L Sbjct: 225 RYENLSRVEKSRLDDFSSLL 244
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 47.5 bits (113), Expect = 5e-08 Identities = 81/375 (21%), Positives = 135/375 (36%), Gaps = 41/375 (10%) Query: 20 FSAGLLGIGQNGLLVVLPVLVIQTNLSLSV---WAALLMLGSMLFLPSSPWWGKQISRTG 76 + L +G ++ VLP L+ S V + LL L +++ +P G R G Sbjct: 12 STVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFG 71 Query: 77 SKPVVLWALGGYGISFTLLGLGSVLMATSAITTAVGLGILIIARIAYGLTVSAMVPACQV 136 +PV+L +L G + + ++ L +L I RI G+T + A Sbjct: 72 RRPVLLVSLAGAAVDYAIMATAPFLW------------VLYIGRIVAGITGATGAVAGAY 119 Query: 137 WALQRAGEGNRMAALATISSGLSCGRLFGPLCAAAMLAIHPLAPLGLLMAAPVLALLMLL 196 A R +S+ G + GP+ M P AP A L L Sbjct: 120 IA-DITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGC 178 Query: 197 RL------PGTPPQPTPECKSVSLKRDCLPYLLCAILLAAAVSMMQLGLSPAL------T 244 L P ++ R + A L+A M +G PA Sbjct: 179 FLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGE 238 Query: 245 RQFATDTTAISQQVAWLLGLSAVAALIAQFGVLRPQRLTPVALLLSAGVLMSGGLAIMLS 304 +F D T I +A L ++A + G + + AL+L +G + + + Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMI-TGPVAARLGERRALMLGMIADGTGYILLAFA 297 Query: 305 EQLWLFYPGCAVLSFGAALATPAYQLLLNDKLADGAGAGWLATSHTLGYGLCALLVPLVS 364 + W+ +P +L+ G + PA Q +L+ + D G L L L S Sbjct: 298 TRGWMAFPIMVLLASG-GIGMPALQAMLS-RQVDEERQGQLQ----------GSLAALTS 345 Query: 365 KTGVAIALIMAALFA 379 T + L+ A++A Sbjct: 346 LTSIVGPLLFTAIYA 360
>PF04183#IucA / IucC family Length = 580 Score = 339 bits (872), Expect = e-111 Identities = 104/480 (21%), Positives = 178/480 (37%), Gaps = 46/480 (9%) Query: 56 ELLIPLDEQKSLHFRVAYFSPTQHHRF-----AFPARLVTASGSYPVDFTTLSRLIIDKL 110 E + + Q + + P RF + + A D L++ ++ +L Sbjct: 24 EQVFHAESQGDDRYCIN--LPGAQWRFIAERGIWGWLWIDAQTLRCADEPVLAQTLLMQL 81 Query: 111 RHQLFLPVPLCETFHQRVLESHVHTQQAIDARHDWAALREKALNFGEAEQALLTGHAFHP 170 + L + Q + + + Q + AR +A LN + Q LL+GH Sbjct: 82 KQVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINLNA-DRLQCLLSGHPKFV 140 Query: 171 APKSHEPFNRREAERYLPDMAPHFPLRWFSVDKTQIAGES-LHLNLQQRLTRFAAENAPQ 229 K + + ERY P+ A F L W +V + + +++ Q LT A PQ Sbjct: 141 FNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRCDNEMDIHQLLT---AAMDPQ 197 Query: 230 LLNELS--------DNQWLF-PLHPWQGEYLLQQGWCQALVAKGLIKDLGEAGTSWLPTT 280 S D+ WL P+HPWQ + + + A+G + LGE G WL Sbjct: 198 EFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADF-AEGRMVSLGEFGDQWLAQQ 256 Query: 281 SSRSLYCATSRD--MIKFSLSVRLTNSIRTLSVKEVKRGMRLARLAQ----TDGWQMLQ- 333 S R+L A+ R IK L++ T+ R + + + G +R Q TD + Sbjct: 257 SLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSG 316 Query: 334 ---VRFPTFRVMQEDGWAGLLDLNGNIMQESLFALRENLLVDQPKSQTNVLVSLTQAAPD 390 + P + +G+A L + REN ++ VL++ + Sbjct: 317 AVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDE 376 Query: 391 GGDSLLVSAVKRLSDRLGITVQQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILV 450 L + + DR G+ A W+ + V+ PL+ YG+ L+AH QNI + Sbjct: 377 NNQPLAGAYI----DRSGLD----AETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITL 428 Query: 451 QMLGDLPVGFIYRDCQGSAFMPHATDWLDSIGEAQAENIFTHEQLLRYFPYYLLVNSTFA 510 M +P + +D QG M + + E + L++ Sbjct: 429 AMKEGVPQRVLLKDFQGD--MRLVKEEFPEMDSLPQE----VRDVTSRLSADYLIHDLQT 482
>PF04183#IucA / IucC family Length = 580 Score = 816 bits (2109), Expect = 0.0 Identities = 565/580 (97%), Positives = 571/580 (98%) Query: 1 MNHKDWDFVNRRLVAKMLSEMEYEQVFHAESQGDDHYCINLPGAQWRFIAERGIWGWLWI 60 MNHKDWD VNRRLVAKMLSE+EYEQVFHAESQGDD YCINLPGAQWRFIAERGIWGWLWI Sbjct: 1 MNHKDWDLVNRRLVAKMLSELEYEQVFHAESQGDDRYCINLPGAQWRFIAERGIWGWLWI 60 Query: 61 DAQTLRCTDEPVLAQTLLMQLKPVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASD 120 DAQTLRC DEPVLAQTLLMQLK VLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASD Sbjct: 61 DAQTLRCADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASD 120 Query: 121 LINLDADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYTNTFRLHWLAVKREHMIWRC 180 LINL+ADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEY NTFRLHWLAVKREHMIWRC Sbjct: 121 LINLNADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRC 180 Query: 181 DNDLDIQQLLTAAMDPQEFTRFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEG 240 DN++DI QLLTAAMDPQEF RFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEG Sbjct: 181 DNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEG 240 Query: 241 RMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASR 300 RMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASR Sbjct: 241 RMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASR 300 Query: 301 WLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLK 360 WLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLK Sbjct: 301 WLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLK 360 Query: 361 PDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGVALI 420 PDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGVALI Sbjct: 361 PDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGVALI 420 Query: 421 AHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEAFPEMDSLPQEVRDVTSRLSADYLIHDL 480 AHGQNITLAMKEGVPQRVLLKDFQGDMRLVKE FPEMDSLPQEVRDVTSRLSADYLIHDL Sbjct: 421 AHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSRLSADYLIHDL 480 Query: 481 QTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMNKHPQMAERFALFSLFRPQIIR 540 QTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYM KHPQM+ERFALFSLFRPQIIR Sbjct: 481 QTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMKKHPQMSERFALFSLFRPQIIR 540 Query: 541 VVLNPVKLTWPDLDGGSRMLPNYLENLQNPLWLVTQEYES 580 VVLNPVKLTWPDLDGGSRMLPNYLE+LQNPLWLVTQEYES Sbjct: 541 VVLNPVKLTWPDLDGGSRMLPNYLEDLQNPLWLVTQEYES 580
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 80.5 bits (198), Expect = 2e-19 Identities = 48/214 (22%), Positives = 74/214 (34%), Gaps = 52/214 (24%) Query: 35 NRKLVATMLSLAVAGTVNA---ANIDISNVWARDYLDLAQNKGIFQPGATDVTITLKNGD 91 N+K ++L VA + A + +V + + D A+NKG F GAT+V + KN Sbjct: 3 NKKFKLNFIALTVAYALTPYTEAALVRDDVDYQIFRDFAENKGKFSVGATNVLVKDKNNK 62 Query: 92 KF--SFHN-LSIPDFSGAAAS-GAATAIGGSYSVTVAH-----------------NKKNP 130 + N + + DFS AT I Y V V H N N Sbjct: 63 DLGTALPNGIPMIDFSVVDVDKRIATLINPQYVVGVKHVSNGVSELHFGNLNGNMNNGNA 122 Query: 131 QAAETQVYAQSSYKVVDRRNSN-------------------DFEIQRLNKFVVETVGATP 171 +A ++ Y V++ D+ + RL+KFV E Sbjct: 123 KAHRDVSSEENRYFSVEKNEYPTKLNGKTVTTEDQTQKRREDYYMPRLDKFVTEVAPIEA 182 Query: 172 AETNPTTYSDALERYGIVTSDGSKKIIGFRAGSG 205 + + +D +K R GSG Sbjct: 183 STAS---------SDAGTYNDQNKYPAFVRLGSG 207
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 756 bits (1954), Expect = 0.0 Identities = 328/870 (37%), Positives = 484/870 (55%), Gaps = 54/870 (6%) Query: 6 IVVGLTAGTCLIFSQNLMAEVSVFNPALLEINHQSGVDIRQFNRANLMPPGVYSVDIFIN 65 V L L + FNP L + Q+ D+ +F +PPG Y VDI++N Sbjct: 26 FFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLN 85 Query: 66 GKMFERQDVTFVQDNPDADLHACFIAIKKTLSSFGIKVDALKSFNDVDETVCLDPAPRIE 125 +DVTF + + + C L+S G+ ++ N + + C+ I Sbjct: 86 NGYMATRDVTFNTGDSEQGIVPCLTR--AQLASMGLNTASVSGMNLLADDACVPLTSMIH 143 Query: 126 GSSWQFDSDKLQLNISIHQIYMDAMAYDYISPTRWDEGINALTINYDFSGSHTLRSDYGS 185 ++ Q D + +LN++I Q +M A YI P WD GINA +NY+FSG+ + Sbjct: 144 DATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSV--QNRIG 201 Query: 186 QETDTSYLNLRNGLNIGPWRLRNYSTLN------TSDGRAEYNSISTWIQRDIAALRSQI 239 + +YLNL++GLNIG WRLR+ +T + +S + ++ I+TW++RDI LRS++ Sbjct: 202 GNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRL 261 Query: 240 MIGDTWTASDIFDSTQIRGARLYTDNDMLPASQNGFAPVVRGIAKSNATVIIRQNGYVIY 299 +GD +T DIFD RGA+L +D++MLP SQ GFAPV+ GIA+ A V I+QNGY IY Sbjct: 262 TLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIY 321 Query: 300 QSAVPQGAFEITDLNTASTGGDLDVTIKEEDGSEQRFTQPYASLAILKREGLTDVDVSVG 359 S VP G F I D+ A GDL VTIKE DGS Q FT PY+S+ +L+REG T ++ G Sbjct: 322 NSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAG 381 Query: 360 ELRDEDG--FTPDVLQAQILHGFSHGITLYGGMQAAENYGSAALGVGKDLGALGAISFDV 417 E R + P Q+ +LHG G T+YGG Q A+ Y + G+GK++GALGA+S D+ Sbjct: 382 EYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDM 441 Query: 418 THARANFSHDDTETGQSYRFLYSKLFDDTDTSLRLVGYRYSTEGYYTLNEWASRRNS--- 474 T A + D GQS RFLY+K +++ T+++LVGYRYST GY+ + R + Sbjct: 442 TQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYN 501 Query: 475 --------------PEDFWETGNRRSRVEGTLTQSLGRDYGNLYLTLSRQQYWHTDDVER 520 + + N+R +++ T+TQ LGR LYL+ S Q YW T +V+ Sbjct: 502 IETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQTYWGTSNVDE 560 Query: 521 LMQFGYSSSWKRLSWNVSWSYSNTARQGTGNNHASDNTSEQIYMLSLSVPLSGW------ 574 Q G +++++ ++W +S+S + A +Q+ L++++P S W Sbjct: 561 QFQAGLNTAFEDINWTLSYSLTKN---------AWQKGRDQMLALNVNIPFSHWLRSDSK 611 Query: 575 --WGNSYATYSVSQNDNSGSSHQLGLSGTALERNNLSWNLMQSYNSHDDEVGGN---MSL 629 W ++ A+YS+S + N ++ G+ GT LE NNLS+++ Y D G+ +L Sbjct: 612 SQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATL 671 Query: 630 TYDGSYGTVNGSYNYSQNSQRLNYGIRGGILAHSEGVTLSQELGETIALVKAPGAAGLEI 689 Y G YG N Y++S + ++L YG+ GG+LAH+ GVTL Q L +T+ LVKAPGA ++ Sbjct: 672 NYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKV 731 Query: 690 DNMRGAATDWRGYTVKTQLNPYDENRVAISDNYFSKSNIELDNTVVTMVPTRGAVVKAEF 749 +N G TDWRGY V Y ENRVA+ N + N++LDN V +VPTRGA+V+AEF Sbjct: 732 ENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLA-DNVDLDNAVANVVPTRGAIVRAEF 790 Query: 750 VTHVGYRVLFRVLNANGKPVPFGAIAAIQDASLADSGIVGDRGELYLSGLPEKGQVTLSW 809 VG ++L L N KP+PFG A + S SGIV D G++YLSG+P G+V + W Sbjct: 791 KARVGIKLLMT-LTHNNKPLPFG--AMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKW 847 Query: 810 GENASTKCIFNYSFSTPESESGLIEQGVTC 839 GE + C+ NY + L + C Sbjct: 848 GEEENAHCVANYQLPPESQQQLLTQLSAEC 877
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 46.4 bits (110), Expect = 9e-08 Identities = 33/141 (23%), Positives = 62/141 (43%), Gaps = 1/141 (0%) Query: 4 VMGAYLLTYGVSQLFYGPISDRVGRRPVILVGMSIFMLATLVA-VTTSSLTVLIAASAMQ 62 V A++LT+ + YG +SD++G + ++L G+ I +++ V S ++LI A +Q Sbjct: 54 VNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQ 113 Query: 63 GMGTGVGGVMARTLPRDLYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWNWRACYL 122 G G + + + A L+ + + + P IGG++ +W L Sbjct: 114 GAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLL 173 Query: 123 FLLVLCAGVTFSMARWMPETR 143 ++ V F M E R Sbjct: 174 IPMITIITVPFLMKLLKKEVR 194
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 2e-13 Identities = 29/174 (16%), Positives = 59/174 (33%), Gaps = 20/174 (11%) Query: 2 ITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDIS 61 T+ + DD +R+ Q L V + + + + D+ MPD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLELLSQLPK---GMATIMLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATG 118 +LL ++ K + +++S ++ +A GA +L K ELI + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR---- 117 Query: 119 GCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQG---MAVKEIAAELGLSPKTV 169 A+ R L + + + + + A L + T+ Sbjct: 118 --------ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL 163
>PF06580#Sensor histidine kinase Length = 349 Score = 39.8 bits (93), Expect = 2e-05 Identities = 28/142 (19%), Positives = 56/142 (39%), Gaps = 11/142 (7%) Query: 365 LRPRQLDDLTLEQAIRSLMREMELEGRGIVSHLEWRIDESALSENQRVTLFRVCQEGLNN 424 LR ++L + + ++L L++ + + +V + Q + N Sbjct: 208 LRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPM-LVQTLVEN 266 Query: 425 IVKHA-----DASAVTLQGWQQDERLMLVIEDDGSGLPPGSGQ-QGFGLTGMRERVTALG 478 +KH + L+G + + + L +E+ GS + + G GL +RER+ L Sbjct: 267 GIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLY 326 Query: 479 G---TLHISCLHG-TRVSVSLP 496 G + +S G V +P Sbjct: 327 GTEAQIKLSEKQGKVNAMVLIP 348
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 40.6 bits (95), Expect = 8e-06 Identities = 65/408 (15%), Positives = 137/408 (33%), Gaps = 60/408 (14%) Query: 29 RHILLTIWLGYALFY--FTRKSFNAAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSG 86 RH + IWL F+ N ++P+I + + + T F +T+ + V G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 87 IVSDRSNARYFMGIGLIATGIMNILFGFSTSLWAFAVLWVLNAFFQGWGS---PVCARLL 143 +SD+ + + G+I +++ S F L ++ F QG G+ P ++ Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHS---FFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 144 TAWY-SRTERGGWWALWNTAHNVGGALIPIVMAASALHYGWRAGMMIAGCMAIVVGIFLC 202 A Y + RG + L + +G + P + A + W ++ M ++ + Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW--SYLLLIPMITIITVPF- 184 Query: 203 WRLRDRPQALGLPAVGEWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLV 262 + L +I G L I+ + Y VL Sbjct: 185 --------LMKLLKKEVRIKGHFDIK----GIILMSVGIVFFMLFTTSYSISFLIVSVLS 232 Query: 263 YVV-----RAAINDWGNLYMSETLGVDLVTANTAVTMFELGGFI-----------GALVA 306 +++ R + + + + + + + + + GF+ A Sbjct: 233 FLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTA 292 Query: 307 GWGSDKLFNGNRGPMNLIFAAGILL-SVGSLWLMPFASYVMQATCFFTIGFFVFGPQMLI 365 GS +F G + + GIL+ G L+++ + + F T F + + Sbjct: 293 EIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFL-SVSFLTASFLLETTSWFM 351 Query: 366 ---------GMAAAECS---------HKEAAGAATGFVGLFAYLGASL 395 G++ + ++ AGA + ++L Sbjct: 352 TIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGT 399
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.1 bits (78), Expect = 0.001 Identities = 28/168 (16%), Positives = 61/168 (36%), Gaps = 17/168 (10%) Query: 49 FNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFMLILSAIC 108 N++ D+ + + + F +T+ +G + +D K+ L F +I++ C Sbjct: 33 LNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIIN--C 90 Query: 109 MLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTI----TKWTPRRKRGTFLGFW 164 +G SL +M + F Q G + + + ++ P+ RG G Sbjct: 91 FGSVIGFVGHSFFSLLIM------ARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLI 144 Query: 165 NISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRY 212 +G + A+Y+ + + + P + I+ L Sbjct: 145 GSIVAMGEGVGPAIGGMIAHYIHWSY---LLLIP--MITIITVPFLMK 187
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 39.7 bits (93), Expect = 3e-05 Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 17/105 (16%) Query: 22 AVSRGDAVADYIIDNVSILDLINAGEISGPIVIKGRYIAGVG-AEYADT---------PA 71 V+R D +I N ILD + G + I +K IA +G A D P Sbjct: 60 QVTREGGAVDTVITNALILD--HWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPG 117 Query: 72 LQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVI 116 + I G G +D+H+H + P E A L GLT ++ Sbjct: 118 TEVIAGEGKIVTAGGMDSHIH----FICPQQIEEA-LMSGLTCML 157
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.4 bits (92), Expect = 2e-05 Identities = 35/208 (16%), Positives = 71/208 (34%), Gaps = 13/208 (6%) Query: 88 IIVEFLPVSLLTP----MAQDLGISEGVAGQSVTVTAFVAMFASLFITQTIQATDR--RY 141 + ++ + + L+ P + +DL S V + A A+ +DR R Sbjct: 14 VALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRR 73 Query: 142 VVILFAVLL-TLSCLLVSFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKA 200 V+L ++ + +++ A +L IGR G+ G A++ + + + Sbjct: 74 PVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARH 132 Query: 201 LSVIFGAVSIALVIAAPLGSFLGELIGWRNVFNAAAVMG----VLCIFWIIKSLPSLPGE 256 + +V LG +G F AAA + + F + +S Sbjct: 133 FGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRP 191 Query: 257 PSHQKQNTFRLLQRPGVMAGMIAIFMSF 284 + N + M + A+ F Sbjct: 192 LRREALNPLASFRWARGMTVVAALMAVF 219
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 185 bits (470), Expect = 2e-54 Identities = 84/316 (26%), Positives = 139/316 (43%), Gaps = 29/316 (9%) Query: 4 YKNDKTFRNLEIFGDSGSGAYLYDNKLEKWVLVGTTHGIASVNGDQLTWITKYNDKLVSE 63 + N + GDSGS ++YD + KW+ +G+ A N Y + + Sbjct: 273 ILSQDPLTNYAVLGDSGSPLFVYDREKGKWLFLGSYDFWAGYNKKSWQEWNIYKSQFTKD 332 Query: 64 LKDTYS----------HKINLNGNNVTIKNTDITLHQNNADTTGTQEKITKDKDIVFTNG 113 + + S + + NG TI + +L N D ++K K + F Sbjct: 333 VLNKDSAGSLIGSKTDYSWSSNGKTSTITGGEKSL---NVDLADGKDKPNHGKSVTFEGS 389 Query: 114 GNVLFKDNLDFGSGGIIFDEGHEYNINGQRFTFKGAGIDIGKESIVNWNALYSSDDVLHK 173 G + +N+D G+GG+ F+ +E T+KGAG+ + + V W D L K Sbjct: 390 GTLTLNNNIDQGAGGLFFEGDYEVKGTSDNTTWKGAGVSVAEGKTVTWKVHNPQYDRLAK 449 Query: 174 IGPGTLNVQKKQG--ANIKIGEGNVILNEEG------TFNNIYLASGNGKVILNKDNSLG 225 IG GTL V+ ++K+G+G VIL ++ F ++ + SG ++LN D + Sbjct: 450 IGKGTLIVEGTGDNKGSLKVGDGTVILKQQTNGSGQHAFASVGIVSGRSTLVLNDDKQVD 509 Query: 226 NDQYAGIFFTKRGGTLDLNGHNQTFTRIAATDDGTTITNSDTKKEAVLAINNEDSYIYHG 285 + I+F RGG LDLNG++ TF I DDG + N + + + I E Sbjct: 510 PN---SIYFGFRGGRLDLNGNSLTFDHIRNIDDGARLVNHNMTNASNITITGESLI---- 562 Query: 286 NINGNIKLTHNINSQD 301 + N +NI++ D Sbjct: 563 -TDPNTITPYNIDAPD 577 Score = 32.7 bits (74), Expect = 0.002 Identities = 52/280 (18%), Positives = 84/280 (30%), Gaps = 42/280 (15%) Query: 71 KINLNGNNVT---IKNTDI-TLHQNNADTTGTQEKITKDKDIVFTNGGNVLFKDNLDFGS 126 +++LNGN++T I+N D N+ T + IT + I N D D + Sbjct: 521 RLDLNGNSLTFDHIRNIDDGARLVNHNMTNASNITITGESLITDPNTITPYNIDAPDEDN 580 Query: 127 GGIIFDEGHEYNI-----NGQRFTFKGAG------IDIGKESIVNWNALYSSDDVLHKIG 175 + N + + ES NW + + D + Sbjct: 581 PYAFRRIKDGGQLYLNLENYTYYALRKGASTRSELPKNSGESNENWLYMGKTSDEAKRNV 640 Query: 176 PGTLNVQKKQGANIKIGEGNVILNEEGTFN-NIYLASGNGKVILNKDNSLGNDQYAGIFF 234 +N ++ G N GE N G N S + +L +L D Sbjct: 641 MNHINNERMNGFNGYFGEEEGKNN--GNLNVTFKGKSEQNRFLLTGGTNLNGD------L 692 Query: 235 TKRGGTLDLNG----HNQTFTRIAATDDGTTITNSDT------------KKEAVLAINNE 278 T GTL L+G H + I++T ++ K + N Sbjct: 693 TVEKGTLFLSGRPTPHARDIAGISSTKKDPHFAENNEVVVEDDWINRNFKATTMNVTGNA 752 Query: 279 DSY--IYHGNINGNIKLTHNINSQDKKTNAKLILDGSVNT 316 Y NI NI ++ + S T Sbjct: 753 SLYSGRNVANITSNITASNKAQVHIGYKTGDTVCVRSDYT 792
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.2 bits (65), Expect = 0.047 Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 10/80 (12%) Query: 367 LGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTT 426 LGD + D V + AG+ N G DV T G AT A T Sbjct: 616 LGDGD--DKVFLSAGSA--NIYAGK------GHDVVYYDKTDTGYLTIDGTKATEAGNYT 665 Query: 427 VTRNVGENALAISRVPQTQK 446 VTR +G + + V + Q+ Sbjct: 666 VTRVLGGDVKVLQEVVKEQE 685
>SECA#SecA protein signature. Length = 901 Score = 30.2 bits (68), Expect = 0.004 Identities = 11/71 (15%), Positives = 30/71 (42%) Query: 14 AKARRKTREELDQEARDRKRQKKRRGHAPGSRAAGGNTTSGSKGQNAPKDPRIGSKTPIP 73 +K + + EE+++ + R+ + +R ++ + + + ++G P P Sbjct: 827 SKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCP 886 Query: 74 LGVTEKVTKQH 84 G +K + H Sbjct: 887 CGSGKKYKQCH 897
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 597 bits (1542), Expect = 0.0 Identities = 206/478 (43%), Positives = 300/478 (62%), Gaps = 11/478 (2%) Query: 1 MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALASKTPDVLLSDIRMPGM 60 M + V DDD++IR VL +AL+ AG N A + +A+ D++++D+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYLPKPFDIDEAVALVERAIS 120 + LL +IK+ P LPV++M+A + A+ A ++GA+DYLPKPFD+ E + ++ RA++ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 HYQEQQQPRNIQLNGPTTDIIGEAQAMQDVFRIIGRLSRSSISVLINGESGTGKELVAHA 180 + + ++G + AMQ+++R++ RL ++ ++++I GESGTGKELVA A Sbjct: 121 EPKRRPSKLEDDSQDGM-PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 181 LHRHSPRTKAPFIALNMAAIPKDLIESELFGHEKGAFTGANTIRQGRFEQADGGTLFLDE 240 LH + R PF+A+NMAAIP+DLIESELFGHEKGAFTGA T GRFEQA+GGTLFLDE Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 241 IGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRIIAATHQNLEQRVQEGKFREDLFHR 300 IGDMP+D QTRLLRVL G++ VGG P++ DVRI+AAT+++L+Q + +G FREDL++R Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 301 LNVIRVHLPPLRERREDIPRLARHFLQVAARELGVEAKLLHPETEAALTRLAWPGNVRQL 360 LNV+ + LPPLR+R EDIP L RHF+Q A +E G++ K E + WPGNVR+L Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVREL 358 Query: 361 ENTCRWLTVMAAGQEVLIQDLPGELFESTVAESTSQMQPDSWATLLAQWADRALRS---- 416 EN R LT + + + + EL + S + ++Q + +R Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 417 -----GHQNLLSEAQPELERTLLTTALRHTQGHKQEAARLLGWGRNTLTRKLKELGME 469 L E+E L+ AL T+G++ +AA LLG RNTL +K++ELG+ Sbjct: 419 FGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>PF06580#Sensor histidine kinase Length = 349 Score = 28.3 bits (63), Expect = 0.042 Identities = 34/190 (17%), Positives = 72/190 (37%), Gaps = 41/190 (21%) Query: 171 IIEQADRLRNLVDRL---LGPQLPGTRVTE-SIHKVAERV---VTLVSMELPDNVRLIRD 223 I+E + R ++ L + L + + S+ V + L S++ D ++ Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 224 YDPSLPELAHDPDQIEQVLLN-IVRNALQ---ALGPEGGEIILRTRTAFQLTLHGERYRL 279 +P++ ++ Q+ +L+ +V N ++ A P+GG+I+L+ Sbjct: 246 INPAIMDV-----QVPPMLVQTLVENGIKHGIAQLPQGGKILLKGT------KDNGTVT- 293 Query: 280 AARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGK---IEFTSWP 336 ++VE+ G + ++ TG GL R + G I+ + Sbjct: 294 ---LEVENTGSLALKNTKE------------STGTGLQNVRERLQMLYGTEAQIKLSEKQ 338 Query: 337 GHTEFSVYLP 346 G V +P Sbjct: 339 GKVNAMVLIP 348
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 180 bits (458), Expect = 4e-51 Identities = 97/445 (21%), Positives = 170/445 (38%), Gaps = 81/445 (18%) Query: 4 KLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQE--RVMDSNDLEKERGITILAKNT 61 K+ NI ++AHVD GKTTL + LL SG + D+ LE++RGITI T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 62 AIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAFDGPMPQTRFVTKKAFAYGL 121 + +W + ++NI+DTPGH DF EV R +S++D +L++ A DG QTR + G+ Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 122 KPIVVINKVDRPGARPDWVVDQVFD-------------LFVNLDATDEQLD--------- 159 I INK+D+ G V + + L+ N+ T+ Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 160 --------------------------------FPIVYASALNGIAGLDHEDMAEDMTPLY 187 FP+ + SA N I G+D+ L Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNI-GIDN---------LI 231 Query: 188 QAIVDHVPAPDVDLDGPFQMQISQLDYNSYVGVIGIGRIKRGKVKPNQQVTIIDSEGKTR 247 + I + + ++ +++Y+ + R+ G + V I + E Sbjct: 232 EVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-- 289 Query: 248 NAKVGKVLGHLGLERIETDLAEAGDIVAITGLGELNISDTVCDTQNVEALPALSVDEPTV 307 K+ ++ + E + D A +G+IV + L ++ + DT+ + + P + Sbjct: 290 --KITEMYTSINGELCKIDKAYSGEIVILQNEF-LKLNSVLGDTKLLPQRERIENPLPLL 346 Query: 308 SMFFCVNTSPFCGKEGKFVTSRQILDRLNKELVHNVALRVEETEDADAFRVSGRGELHLS 367 + + D L LR +S G++ + Sbjct: 347 QTTVEPSKPQQREMLLDALLEISDSDPL---------LRYYVDSATHEIILSFLGKVQME 397 Query: 368 VLIENMRRE-GFELAVSRPKVIFRE 391 V ++ + E+ + P VI+ E Sbjct: 398 VTCALLQEKYHVEIEIKEPTVIYME 422 Score = 32.5 bits (74), Expect = 0.005 Identities = 13/75 (17%), Positives = 29/75 (38%), Gaps = 1/75 (1%) Query: 398 EPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIGFRSEFMT 457 EPY + + +++ + ++ + V L IP+R + +RS+ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKN-NEVILSGEIPARCIQEYRSDLTF 595 Query: 458 MTSGTGLLYSTFSHY 472 T+G + + Y Sbjct: 596 FTNGRSVCLTELKGY 610
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 42.0 bits (98), Expect = 2e-06 Identities = 32/155 (20%), Positives = 64/155 (41%), Gaps = 5/155 (3%) Query: 114 LTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQQLAEQQRLAQQSR 173 + +QAD+ P+ E+ ++ P + +AE + Q+S+ Sbjct: 992 VDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSK--QESK 1049 Query: 174 TTEQSWQQQT-RTSQAAPVQAQPRQSKPASTQQPYQDLLQTPAHTTAQSKPQQAAPVARA 232 T E++ Q T T+Q V + + + A+TQ + T ++ ++ A V + Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 233 ADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQ 267 A T + ++ + Q + EQ+ETV+ Q Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQ--EQSETVQPQ 1142
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 35.1 bits (81), Expect = 4e-04 Identities = 21/85 (24%), Positives = 37/85 (43%), Gaps = 20/85 (23%) Query: 26 CDVLVANGKIIAVASNIPSDIVPNCT--------VVDLSGQILCPGFIDQHVHLIGGGGE 77 D+ + +G+I A+ D+ P T V+ G+I+ G +D H+H I Sbjct: 86 ADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFI----- 140 Query: 78 AGPTTRTPEVALSRLTEAGVTSVVG 102 + E AL +G+T ++G Sbjct: 141 ---CPQQIEEALM----SGLTCMLG 158
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.008 Identities = 10/49 (20%), Positives = 25/49 (51%) Query: 230 LVPLIPAIIMISTTIANIWLVKDTPAWEVVNFIGSSPIAMFIAMVVAFV 278 + +I ++ I +W V +T W ++ FI + P+A + + ++ + Sbjct: 73 MGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLALSII 121
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 28.1 bits (62), Expect = 0.047 Identities = 19/79 (24%), Positives = 32/79 (40%), Gaps = 1/79 (1%) Query: 211 SQNLGYYLSGTTADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVS 270 S+N G ++ +A+ N FT PA V V L ++G ++ + + + Sbjct: 133 SENAGKEITIGSAN-PNVTFTEKTGDQPASTVKVTLDQDGVAKLSSVQIKNVYAIDTTYN 191 Query: 271 LGLTANYARTGGQVTAGNV 289 + TG VT G V Sbjct: 192 SNVNFYDVTTGATVTTGAV 210
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 33.5 bits (76), Expect = 4e-04 Identities = 30/158 (18%), Positives = 49/158 (31%), Gaps = 9/158 (5%) Query: 3 WCKRGYVLAAMLALASATIQAADVTITVNGKVVAKPCTVSTTNATVDLGDLYSFSLMSAG 62 W R + A LA + +TI + VT VN + + + + G Sbjct: 258 WMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGDHNAAQAGIIASNKTH------IG 311 Query: 63 AASAWHDVALELTNCPVG--TSRVTASFSGAADSTGYYKNQGTAQNIQLELQDDSGNTLN 120 W L + P G + S + Q ++QN + N+ Sbjct: 312 TLDLWQSAGLNIIAPPEGGYKDKPNDKPSNTTQNNAKNDKQESSQNNSNTQVINPPNSAQ 371 Query: 121 TGATKTVQVDDSSQSAHFPLQVRALTVNGGATQGTIQA 158 + QV D + V +N A GTI+ Sbjct: 372 KTEIQPTQVIDGPFAGGKNTVVNINRINTNA-DGTIRV 408
>SECA#SecA protein signature. Length = 901 Score = 32.2 bits (73), Expect = 0.005 Identities = 26/144 (18%), Positives = 54/144 (37%), Gaps = 6/144 (4%) Query: 282 HVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLEDFEPRIDRDEENK-PIRV 340 ++D +DV N + IDA+ P L ++ + + R+ D + PI Sbjct: 665 ELLDVSDVSETINSIREDVFKATIDAYIPPQSL--EEMWDIPGLQERLKNDFDLDLPIAE 722 Query: 341 WLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSV 400 WL + L + + + + + + R + LQ ++ W E ++ Sbjct: 723 WLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAM 782 Query: 401 SLQVRMPIVDWRRLCKQEPALIDY 424 +R I R +++P +Y Sbjct: 783 D-YLRQGIH-LRGYAQKDP-KQEY 803
>cloacin#Cloacin signature. Length = 551 Score = 31.6 bits (71), Expect = 0.006 Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 10/81 (12%) Query: 17 GSSKPGGNSEGNGNKGGRDQGPPDLDDIFRKLSKKLGGLGGGKGTGSGGGSSSQGP---- 72 S G +SE N GG G G GGG GTG G S+ P Sbjct: 33 ASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTG-GNLSAVAAPVAFG 91 Query: 73 -----RPQLGGRVVTIAAAAI 88 P GG V+I+A A+ Sbjct: 92 FPALSTPGAGGLAVSISAGAL 112
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.026 Identities = 12/55 (21%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 179 VVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAV-GKIVEVLGDNM 232 +VP+D L L+ I +G ++++ P R + GK+ + D + Sbjct: 359 IVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAI 413
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 26.7 bits (59), Expect = 0.013 Identities = 7/45 (15%), Positives = 16/45 (35%), Gaps = 1/45 (2%) Query: 4 KRYPEEFKTEAVKQVVDR-GYSVASVATRLDITTHSLYAWIKKYG 47 R E + + + + A L + ++L I++ G Sbjct: 430 DRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELG 474
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 29.4 bits (66), Expect = 0.021 Identities = 17/69 (24%), Positives = 29/69 (42%), Gaps = 10/69 (14%) Query: 233 FISGTGFATDYRRLSGHALKGSEIIRLVEESDPVAELALRRYELRLAKSLAHVVNILDP- 291 +G ++D+R L A + D A+LAL + R+ K++ + Sbjct: 273 VYGISGISSDFRDLEDAAF---------KNGDKRAQLALNVFAYRVKKTIGSYAAAMGGV 323 Query: 292 DVIVLGGGM 300 DVIV G+ Sbjct: 324 DVIVFTAGI 332
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 52.9 bits (127), Expect = 1e-09 Identities = 73/356 (20%), Positives = 126/356 (35%), Gaps = 36/356 (10%) Query: 5 ILSLALGTFGLGMAEFGIMSVLTELAHNVGISIPAAGH---MISYYALVVVVGAPIIALF 61 + ++AL G+G+ IM VL L ++ S H +++ YAL+ AP++ Sbjct: 11 LSTVALDAVGIGL----IMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 62 SSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIK 121 S R+ + +LL +A + A+ + +L IGR+V+G GA + I Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD--IT 124 Query: 122 PGKVTAAVAGMVSGMTVANLLGIP-LGTYLSQECWRYTFLLIAVFNIAVMASVYFWVPDI 180 G A G +S ++ P LG + F A N + F +P+ Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 181 RDEAKGNLREQ----------FHFLRSPAPWLI--FAATMFGNAGVFAWFSYVKPYMMFI 228 + LR + + A + F + G W + Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG------E 238 Query: 229 SGFSETAMTFIMMLVGLGM---VLGNMLSGRISGRYSPLRIAAVTDFIIVLALLMLFFCG 285 F A T + L G+ + M++G ++ R R + ++L F Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 286 GMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAF--NLGSAVG 339 I + G+ LQ +L + E G G +A +L S VG Sbjct: 299 RGWMAFPIMVLLASGGIG--MPALQAMLSRQV-DEERQGQLQGSLAALTSLTSIVG 351
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 39.4 bits (92), Expect = 7e-05 Identities = 34/199 (17%), Positives = 71/199 (35%), Gaps = 14/199 (7%) Query: 671 QQEAQSWQQRQNELTALQNRIQQLTPILETLPQSDDLPHSEETVALDNWRQVHEQCLALH 730 + + Q + Q R Q L+ +E + E + +V + Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192 Query: 731 SQQQTLQQQDVLAAQSLQKAQAQFDTAL--------QASVFDDQQAFLAALMDEQTLTQL 782 Q T Q Q +L K +A+ T L + V + ++L+ +Q + Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIA-- 250 Query: 783 EQLKQNLENQRRQAQTLVTQTAETLAQHQQHRPDGLALTVTVEQIQQEL-AQTHQKLREN 841 K + Q + V + +Q +Q + L+ + + Q + KLR+ Sbjct: 251 ---KHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQT 307 Query: 842 TTSQGEIRQQLKQDADNRQ 860 T + G + +L ++ + +Q Sbjct: 308 TDNIGLLTLELAKNEERQQ 326 Score = 39.4 bits (92), Expect = 7e-05 Identities = 25/204 (12%), Positives = 59/204 (28%), Gaps = 18/204 (8%) Query: 487 EARIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEG 546 EA ++ Q + Q ++E + E + +E + L Sbjct: 133 EADTLKTQSSLLQARLEQ---TRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLT- 188 Query: 547 AALRGQLDALTKQLQRDENEAQSLRQDEQALTQQWQAVTASLNITLQPQDDIQPWLDAQD 606 + ++ Q Q + E R + + + + DD L Q Sbjct: 189 SLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQA 248 Query: 607 -------EHERQL-RLLSQRHELQGQIAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLP 658 E E + +++ + Q+ +I+ +++ + Q L Sbjct: 249 IAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLF------KNEILD 302 Query: 659 QEDEEESWLATRQQEAQSWQQRQN 682 + + + E ++RQ Sbjct: 303 KLRQTTDNIGLLTLELAKNEERQQ 326 Score = 32.5 bits (74), Expect = 0.009 Identities = 16/150 (10%), Positives = 42/150 (28%), Gaps = 5/150 (3%) Query: 731 SQQQTLQQQDVLAAQSLQKAQAQFDTA----LQASVFDDQQAFLAALMDEQTLTQLEQLK 786 + Q + A + Q + L D+ F +E+ L +K Sbjct: 134 ADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVS-EEEVLRLTSLIK 192 Query: 787 QNLENQRRQAQTLVTQTAETLAQHQQHRPDGLALTVTVEQIQQELAQTHQKLRENTTSQG 846 + + Q + A+ + L L + ++ Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKH 252 Query: 847 EIRQQLKQDADNRQQQQTLMQQIAQMTQQV 876 + +Q + + + + Q+ Q+ ++ Sbjct: 253 AVLEQENKYVEAVNELRVYKSQLEQIESEI 282
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 30.8 bits (69), Expect = 0.010 Identities = 14/70 (20%), Positives = 25/70 (35%), Gaps = 4/70 (5%) Query: 149 KQQHLLAAITDYYQQHYADACKLRGDQPLPIIATGHLTTVGSSKSDAVRDIYIGTLDAFP 208 K+ ++ I ++Y + + + I T S+ D + + I A Sbjct: 135 KEAQMMNEIAEFYAAPFKKTRAINEKEAFECI-YDSRTR--SAGKD-IVSVKINIDKAKK 190 Query: 209 AQNFPPADYI 218 N P DYI Sbjct: 191 ILNLPECDYI 200
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.5 bits (235), Expect = 1e-24 Identities = 32/149 (21%), Positives = 63/149 (42%), Gaps = 9/149 (6%) Query: 4 RILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGIQ 63 ILV +D+A IR ++ L + G+ + + + DL++ D ++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 FIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRI 123 + +K+ D+PV++++A+ ++ E GA DY+ KPF EL+ I + Sbjct: 65 LLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA-- 120 Query: 124 SPMAVEEVIKMQGLSLNPTSHRVMAGEEP 152 E + L + + G Sbjct: 121 -----EPKRRPSKLEDDSQDGMPLVGRSA 144
>PF06580#Sensor histidine kinase Length = 349 Score = 34.1 bits (78), Expect = 0.001 Identities = 19/105 (18%), Positives = 33/105 (31%), Gaps = 26/105 (24%) Query: 325 LVYNAVNH----TPEGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKAR 380 LV N + H P+G I ++ + VE+ G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN---------------- 306 Query: 381 SRQTGGSGLGLAIVKHAVNH---HESRLNIESTVGKGTRFSFVIP 422 +G GL V+ + E+++ + GK +IP Sbjct: 307 --TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM-VLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.043 Identities = 16/73 (21%), Positives = 29/73 (39%), Gaps = 13/73 (17%) Query: 60 ERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIG 119 E P+ E + ++G+ A + +Y RL D +++ G Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQ----EIYRVLARLMQTD---------LTLMITG 167 Query: 120 PTGSGKTLLAETL 132 +G+GK L+A L Sbjct: 168 ESGTGKELVARAL 180
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 35.0 bits (80), Expect = 0.001 Identities = 34/133 (25%), Positives = 69/133 (51%), Gaps = 15/133 (11%) Query: 191 ERLEYLMAMMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKELGEMDDVPD- 249 LE A +E + +L R +++ ++ S+ +Q++A ++L E + + + Sbjct: 291 AALEAEKADLEHQSQVLNAN---RQSLRRDLDASREAK---KQLEAEHQKLEEQNKISEA 344 Query: 250 ENEALKRKIDAAKMPKEAKEKAEAELQKLKMMSPMS-AEATVVRGYIDWMVQVPWNARSK 308 ++L+R +DA++ EAK++ EAE QKL+ + +S A +R +D + A+ + Sbjct: 345 SRQSLRRDLDASR---EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASRE----AKKQ 397 Query: 309 VKKDLRQAQEILD 321 V+K L +A L Sbjct: 398 VEKALEEANSKLA 410
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 117 bits (294), Expect = 3e-38 Identities = 49/88 (55%), Positives = 67/88 (76%) Query: 2 NKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVALVGFGTFAVKERAARTGR 61 NK LI K+A +++K + A+DA+ ++V+ L +G+ V L+GFG F V+ERAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEITIAAAKVPSFRAGKALKDAV 89 NPQTG+EI I A+KVP+F+AGKALKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 47.2 bits (112), Expect = 3e-08 Identities = 36/146 (24%), Positives = 63/146 (43%), Gaps = 5/146 (3%) Query: 197 AREREQGTLDQLLVSPLTTWQIFIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALF 256 R Q T + +L + L I +G+ A A IG+ A + + L+L Sbjct: 92 GRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGA---GIGVVAAALGYTQWLSLL 148 Query: 257 YFTMVI--YGLSLVGFGLLISSLCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQN 314 Y VI GL+ G+++++L + + + P + LSG V PV+ +P+ Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 315 LTWINPIRHFTDITKQIYLKDASLDI 340 P+ H D+ + I L +D+ Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDV 234
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.012 Identities = 20/90 (22%), Positives = 28/90 (31%), Gaps = 21/90 (23%) Query: 298 TPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKELTKKFGDFAATDHVNFAV 357 PR E + +LG P + + + K HV + Sbjct: 547 VPRLEKWLVHVLGKTPDDYKP-------------RRLRYLQLVGKYI----LMGHVARVM 589 Query: 358 KRGEIFG----LLGPNGAGKSTTFKMMCGL 383 + G F L G G GKST + GL Sbjct: 590 EPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619 Score = 29.3 bits (65), Expect = 0.047 Identities = 11/23 (47%), Positives = 13/23 (56%) Query: 39 YVTGLVGPDGAGKTTLMRMLAGL 61 Y L G G GK+TL+ L GL Sbjct: 597 YSVVLEGTGGIGKSTLINTLVGL 619
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 62.5 bits (152), Expect = 5e-13 Identities = 42/259 (16%), Positives = 92/259 (35%), Gaps = 25/259 (9%) Query: 83 ALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVKQAQAAYDYEQNFYNRQQGLWKSRT 142 Q + + +A+ +LA E + + + + L + Sbjct: 201 QKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENK 260 Query: 143 ISA--NDLENARSSRDQAQATLKSAQDKLRQYRSGNREQ---DIAQAKASLEQAQAQLAQ 197 N+L +S +Q ++ + SA+++ + + + + Q ++ +LA+ Sbjct: 261 YVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAK 320 Query: 198 AELNLQDSTLIAPSDGTLLTRAV-EPGTVLNEGGTVFTVSLT-RPVWVRAYVDERNLDQA 255 E Q S + AP + V G V+ T+ + + V A V +++ Sbjct: 321 NEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFI 380 Query: 256 QPGRKVLLYTDGRPDKPYH---GQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVT--- 309 G+ ++ + P Y G++ ++ A D R LV+ + I + Sbjct: 381 NVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA--------IEDQRLGLVFNVIISIEENC 432 Query: 310 ----DADDALRQGMPVTVQ 324 + + L GM VT + Sbjct: 433 LSTGNKNIPLSSGMAVTAE 451
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 73.1 bits (179), Expect = 6e-18 Identities = 33/214 (15%), Positives = 77/214 (35%), Gaps = 17/214 (7%) Query: 13 KGEQAKKQLIAAALAQFGEYGMNATT-REIAAQAGQNIAAITYYFGSKEDLYLACAQWIA 71 + ++ ++ ++ AL F + G+++T+ EIA AG AI ++F K DL+ + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 72 DFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRACRNMIKLLTQDDTVNLSKFISREQL 131 IGE E + P + +RE+++ + + + + + F E + Sbjct: 68 SNIGELEL---EYQAKFPGDP---LSVLREILIHVLESTVTEERRRLLMEII-FHKCEFV 120 Query: 132 SPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDANDTRMILHTHALIGEILAFRLGKETIL 191 A + + + + + +A L T + + G Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKH--CIEAKMLPADLMTRRAAIIMRGYISG----- 173 Query: 192 LRTGWTAFDEEKTELINQTVTCHIDLILQGLSQR 225 L W + + + ++ ++L+ Sbjct: 174 LMENWLFAPQSFD--LKKEARDYVAILLEMYLLC 205
>SECA#SecA protein signature. Length = 901 Score = 30.6 bits (69), Expect = 0.013 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Query: 246 QQVLVFTRTKHGANHLAEQLNKDGIRSVAIHG-NKSQGARTRALADFKSGDIRVLVATDI 304 Q VLV T + + ++ +L K GI+ ++ + A A A + + V +AT++ Sbjct: 450 QPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAA---VTIATNM 506 Query: 305 AARGLDI 311 A RG DI Sbjct: 507 AGRGTDI 513
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 38.7 bits (90), Expect = 3e-05 Identities = 28/155 (18%), Positives = 61/155 (39%), Gaps = 5/155 (3%) Query: 48 QAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQ 107 A +WV T+ + G + G LSD++G + ++L G++ + + + Sbjct: 48 PASTNWVNTAFMLTFSIGTAV---YGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFS 104 Query: 108 FTLL-RFLQGISFCFIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLVGAAWIH 166 ++ RF+QG A+ + + K L+ ++ + +GP +G H Sbjct: 105 LLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAH 164 Query: 167 VLPWEGMFVLFAALAAISFFGLQRAMPETAMRIGE 201 + W +L + I+ L + + + G Sbjct: 165 YIHW-SYLLLIPMITIITVPFLMKLLKKEVRIKGH 198
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.1 bits (75), Expect = 0.002 Identities = 24/61 (39%), Positives = 29/61 (47%), Gaps = 1/61 (1%) Query: 302 DSAWVAGVSVVLWGLGASLGFPLTISAASDTGPDAPTRVSVVATTGYLAFLVGPPLLGYL 361 D +W+AG +VVLW SL LT DT PD R ++A YL F P L Sbjct: 270 DWSWLAGCTVVLWPDCDSLREKLTRQELKDT-PDPLAREKLLAAKPYLPFDKQPGQKAML 328 Query: 362 G 362 G Sbjct: 329 G 329
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 46.2 bits (109), Expect = 1e-08 Identities = 13/83 (15%), Positives = 29/83 (34%), Gaps = 4/83 (4%) Query: 2 RRANDPQRRGKMIQATLEAVKLYGIHAVTHRKIATLAGVPLGSMTYYFSGIDELLLEAFS 61 + + R ++ L G+ + + +IA AGV G++ ++F +L E + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW- 63 Query: 62 SFTEIMSRQYQAFFSDVSDAQGA 84 E+ + Sbjct: 64 ---ELSESNIGELELEYQAKFPG 83
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.1 bits (73), Expect = 0.006 Identities = 21/106 (19%), Positives = 34/106 (32%), Gaps = 6/106 (5%) Query: 394 LMIGMITFQFSTFSFGMGNAAGLLFAGIML-GFMRANHPTFG-YIPQ--GALSMVKEFGL 449 L++ + +L+ G ++ G A G YI + FG Sbjct: 76 LLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGF 135 Query: 450 MVFMAGVGLSAGSGINNGLGAIGGQM--LIAGLIVSLVPVVICFLF 493 M G G+ AG + +G A + L + CFL Sbjct: 136 MSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLL 181
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 29.9 bits (67), Expect = 0.010 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 9/54 (16%) Query: 2 RRVFWLVAAALLLAGCAGEKGIVEKEGYQLDTRHQAQAAYPRIKVLVIHYTADD 55 R+V LV ALL AG A I K+G +LD Y ++ L HY +DD Sbjct: 3 RKVLALVIPALLAAGAAHAAEIYNKDGNKLDL-------YGKVDGL--HYFSDD 47
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 74.0 bits (182), Expect = 6e-17 Identities = 70/363 (19%), Positives = 123/363 (33%), Gaps = 65/363 (17%) Query: 13 MKVLVTGATSGLGRNAVEFLCQKGISVRA---------SGRNEAMGKLLEKMGAEFVPTD 63 MK LVTGA +G + + L + G V +A +LL + G +F D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 64 LTELVSSQAKVMLAGIDTLWHCS-------SFTSPWGTQQAFDLANVRATRRLGEWAVAW 116 L + + ++ S +P A+ +N+ + E Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPH----AYADSNLTGFLNILEGCRHN 116 Query: 117 GVRNFIHISSPSLYFDYHHHRNIKEDFRPHRFANEFARSKAASEEVINMLSQANPQTRFT 176 +++ ++ SS S+Y + D + +A +K A+E + + S T Sbjct: 117 KIQHLLYASSSSVYGL-NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSH-LYGLPAT 174 Query: 177 ILRPQSLFGPHDK--VFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLASQEA 234 LR +++GP + + + + M SI + + G D TY ++ A+ Sbjct: 175 GLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVI 234 Query: 235 CDKLPS--------------GRVYNITNGEHRTLRSIVQKLIDELNIDCRIRSVPYPMLD 280 RVYNI N L +Q L D L I+ + +P D Sbjct: 235 PHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGD 294 Query: 281 MIARSMERLGRKSAKEPPLTHYGASKLNFDFTLDITRAQEELGYQPVITLDEGIEKTAAW 340 + T D E +G+ P T+ +G++ W Sbjct: 295 V----------------LETS-----------ADTKALYEVIGFTPETTVKDGVKNFVNW 327 Query: 341 LRD 343 RD Sbjct: 328 YRD 330
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 55.6 bits (134), Expect = 2e-10 Identities = 29/125 (23%), Positives = 52/125 (41%), Gaps = 17/125 (13%) Query: 4 RILVLGASGYIGQHLVRTLSQQGHQILA---------AARHVDRLAKLQLANVSCHKVDL 54 + LV GA+G+IG H+ + L + GHQ++ + RL L HK+DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 55 SWPDNLPALLQD--IDTVYFLVH------SMGEGGDFIAQERQLALNVRDALREVPVKQL 106 + + + L + V+ H S+ + LN+ + R ++ L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 107 IFLSS 111 ++ SS Sbjct: 122 LYASS 126
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 39.6 bits (92), Expect = 4e-05 Identities = 16/49 (32%), Positives = 28/49 (57%) Query: 594 TLTNGALEASNVDLSKELVNMIVAQRNYKSNAQTIKTQDQILNTRVNLR 642 L+N S V+L +E N+ Q+ Y +NAQ ++T + I + +N+R Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 37.6 bits (87), Expect = 2e-04 Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 4/56 (7%) Query: 246 AVSGLNAAATNLDVIGNNIANSATYGFKSGTASFAD----MFAGSKVGLGVKVAGI 297 A+SGLNAA L+ NNI++ G+ T A + AG VG GV V+G+ Sbjct: 7 AMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGV 62
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.8 bits (103), Expect = 4e-07 Identities = 18/81 (22%), Positives = 36/81 (44%), Gaps = 14/81 (17%) Query: 3 SSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDLLYQTIRQPGAQSSEQTTL 62 S + A +GL+A Q ++ +NN+++ + G+ RQ + + +TL Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANSTL 47 Query: 63 PSGLQIGTGVRPVATERLHSQ 83 +G +G GV +R + Sbjct: 48 GAGGWVGNGVYVSGVQREYDA 68 Score = 41.1 bits (96), Expect = 3e-06 Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 220 ETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL 260 S VN+ EE N+ + Q+ Y N++ + T + + L + Sbjct: 505 SISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 349 bits (897), Expect = e-126 Identities = 232/232 (100%), Positives = 232/232 (100%) Query: 1 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY Sbjct: 1 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60 Query: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 120 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA Sbjct: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 120 Query: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF Sbjct: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180 Query: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM Sbjct: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 427 bits (1100), Expect = e-152 Identities = 157/363 (43%), Positives = 213/363 (58%), Gaps = 9/363 (2%) Query: 4 FLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLN 63 F + L A RI+D+ S+Q R N LIGYGLVVGL GTGD +PFT Q++ Sbjct: 13 FSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMR 72 Query: 64 NMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQTIDVVVSSMGNAKSLRGGTLLM 123 ML LGIT G + KN+AAVMVTA+LPPF G +DV VSS+G+A SLRGG L+M Sbjct: 73 AMLQNLGITTQGGQS-NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIM 131 Query: 124 TPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAVIERELPSQFGVGN 183 T L G D Q+YA+AQG ++V G A +++ R+ NGA+IERELPS+F Sbjct: 132 TSLSGADGQIYAVAQGALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSV 191 Query: 184 TLNLQLNDEDFSMAQQIADTINRVR----GYGSATALDARTIQVRVPSGNSSQVRFLADI 239 L LQL + DFS A ++AD +N G A D++ I V+ P + R +A+I Sbjct: 192 NLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPRV-ADLTRLMAEI 250 Query: 240 QNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQANVSQPDTPFGG 299 +N+ V T AKVVIN RTG++V+ +V + AV+ G L+V V V QP PF Sbjct: 251 ENLTVE-TDTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQP-APFSR 308 Query: 300 GQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRALNALGATPMDLMSILQSMQSAGCLR 359 GQT V PQT I Q G + ++ L +V LN++G +++ILQ ++SAG L+ Sbjct: 309 GQTAVQPQTDIMAMQEGSKV-AIVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGALQ 367 Query: 360 AKL 362 A+L Sbjct: 368 AEL 370
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 503 bits (1297), Expect = 0.0 Identities = 308/313 (98%), Positives = 309/313 (98%) Query: 1 MISDSKLLASAAWDAQSLNELKAKASEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60 MISDSKLLASAAWDAQSLNELKAKA EDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG Sbjct: 1 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60 Query: 61 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET Sbjct: 61 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120 Query: 121 VVRYQNQTLSQLVQKAVPRNYDDSLPGDSRAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180 VVRYQNQ LSQLVQKAVPRNYDDSLPGDS+AFLAQLSLPAQLASQQSGVPHHLILAQAAL Sbjct: 121 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180 Query: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGQVTEITTTEYENGEAKKVKAKFRVYSSYL 240 ESGWGQRQIRRENGEPSYNLFGVKASGNWKG VTEITTTEYENGEAKKVKAKFRVYSSYL Sbjct: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 240 Query: 241 EALSDYVGLLTRNPRYAAVTTAASAEQGAQVLQDAGYATDPHYARKLTNMIQQMKSISDK 300 EALSDYVGLLTRNPRYAAVTTAASAEQGAQ LQDAGYATDPHYARKLTNMIQQMKSISDK Sbjct: 241 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK 300 Query: 301 VSKTYSMNIDNLF 313 VSKTYSMNIDNLF Sbjct: 301 VSKTYSMNIDNLF 313
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 68.2 bits (166), Expect = 2e-13 Identities = 49/261 (18%), Positives = 87/261 (33%), Gaps = 26/261 (9%) Query: 548 VAPAPKAATATPAAPAQPGLLSRFFGALKALFSGGEEAKPTEQP-TPKAEAKPERQQDRR 606 T P + S E A+ E P P A A P Sbjct: 991 TVDTTNITTPNNIQADVPSVPSN----------NEEIARVDEAPVPPPAPATPSET---- 1036 Query: 607 KPRQSNRRDRNERRDTRSERTEGSDNREENRRNRRQAQQQTAETRESRQQAEV------T 660 + N ++++++ D E +NR A++ + + + Q EV T Sbjct: 1037 ----TETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSET 1092 Query: 661 EKARTTDEQQAPRRERSRRRNDDKRQAQQEAKALNVEEQSVQETEQEERVRPVQPRRKQR 720 ++ +TT+ ++ E+ + + + Q+ K + + QE + + + R Sbjct: 1093 KETQTTETKETATVEKEEKAKVETEKTQEVPK-VTSQVSPKQEQSETVQPQAEPARENDP 1151 Query: 721 QLNQKVRYEQSVAEEAVVAPVVEETAAAEPIVQEAPAPRTELVKVPLPVVAQTAPEQQEE 780 +N K Q+ P E ++ E V E+ T V P A Q Sbjct: 1152 TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTV 1211 Query: 781 NNADNRDNGGMPRRSRRSPRH 801 N+ + RRS RS H Sbjct: 1212 NSESSNKPKNRHRRSVRSVPH 1232 Score = 61.2 bits (148), Expect = 2e-11 Identities = 48/288 (16%), Positives = 88/288 (30%), Gaps = 36/288 (12%) Query: 510 PSEEEFAERKRPEQPALATFAMPDVPPAPT-PAEPAATVVAPAPKAATATPAAPAQPGLL 568 P E+ + DVP P+ E A AP P A ATP+ + Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE---- 1038 Query: 569 SRFFGALKALFSGGEEAKPTEQPTPKAEAKPERQQDRRKPRQSNRRDRNERRDTRSER-- 626 A E +K + K E Q+ + + + ++ Sbjct: 1039 ------TVA-----ENSKQESKTVEKNEQDATE-----TTAQNREVAKEAKSNVKANTQT 1082 Query: 627 TEGSDNREENRRNRRQAQQQTAETRESRQQAEVTEKARTTDEQQAPRRERSRRRNDDKRQ 686 E + + E + + ++TA + + TEK + + + + + + Q Sbjct: 1083 NEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQ 1142 Query: 687 AQ---QEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSV--AEEAVVAPV 741 A+ + +N++E Q + +P + + Q V +V V P Sbjct: 1143 AEPARENDPTVNIKEPQSQTNTTADTEQPA--KETSSNVEQPVTESTTVNTGNSVVENPE 1200 Query: 742 VEETAAAEPIVQEAPA------PRTELVKVPLPVVAQTAPEQQEENNA 783 A +P V + R + VP V T A Sbjct: 1201 NTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 140 bits (355), Expect = 2e-38 Identities = 60/206 (29%), Positives = 100/206 (48%), Gaps = 1/206 (0%) Query: 258 GKAFYYQPVLCTVQAKSTLTAEEEQDRLRQAIDFTLLDLMTLTAKAEASGLDDIAAIFSG 317 KAF + ++ S E ++L A++ + +L + + EAS D A IF+ Sbjct: 17 AKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTEASMGADKAEIFAA 76 Query: 318 HHTLLGDPELLAAASELLQHEHCTAEYAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLH 377 H +L DPEL+ +++E AEYA ++V ++ +D+EY++ R D+ D+ Sbjct: 77 HLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEYMKERAADIRDVSK 136 Query: 378 RTLVHLT-QTKEELPQFNSPTILLAENIYPSTVLQLDPAVVKGICLSAGSPVSHSALIAR 436 R L HL L T+++AE++ PS QL+ VKG G SHSA+++R Sbjct: 137 RVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHSAIMSR 196 Query: 437 ELGIGWICQQGEKLYAIQPEETLTLD 462 L I + E IQ + + +D Sbjct: 197 SLEIPAVVGTKEVTEKIQHGDMVIVD 222
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 28.5 bits (63), Expect = 0.020 Identities = 10/47 (21%), Positives = 26/47 (55%) Query: 138 VESLRQSSEQNLSVPVALEAASSIAESAAQSTITMQARKGRASYLGE 184 E++ + ++N + +EA ++A +A + + A+ G+A+ G+ Sbjct: 293 REAVDRWIQENPNAAETVEAVFNVAAAAKVAKLAKAAKPGKAAVSGD 339
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 244 bits (624), Expect = 1e-75 Identities = 91/363 (25%), Positives = 155/363 (42%), Gaps = 33/363 (9%) Query: 311 QMRQLMTSQLGKVSHTFAHMPQDDPQTRRLIHFGRQAARSSFPVLLCGEEGVGKALLSQA 370 + S+L S + + + + ++ +++ GE G GK L+++A Sbjct: 120 AEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 371 IHNESERAAGPYIAVNCELYGDAALAEEFIG---GDRTDNENGRLSRLELAHGGTLFLEK 427 +H+ +R GP++A+N + E G G T + R E A GGTLFL++ Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 428 IEYLAVELQSALLQVIKQGVITRLDARRLIPIDVKVIATTTADLAMLVEQNRFSRQLYYA 487 I + ++ Q+ LL+V++QG T + R I DV+++A T DL + Q F LYY Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 488 LHAFEITIPPLRMRRGSIPALVNNKLRSLEKRFSTRLKIDDDALARLVSCAWPGNDFELY 547 L+ + +PPLR R IP LV + ++ EK + D +AL + + WPGN EL Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELE 359 Query: 548 SVIENLALSSDNGRIRVSDLPEHLFTEQATDDVSATRLSTS------------------- 588 +++ L I + L +E + + Sbjct: 360 NLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASF 419 Query: 589 -----------LSFAEVEKEAIINAAQVTGGRIQEMSALLGIGRTTLWRKMKQHGIDAGQ 637 AE+E I+ A T G + + LLG+ R TL +K+++ G+ + Sbjct: 420 GDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSVYR 479 Query: 638 FKR 640 R Sbjct: 480 SSR 482
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 212 bits (540), Expect = 3e-59 Identities = 247/980 (25%), Positives = 402/980 (41%), Gaps = 117/980 (11%) Query: 14 RLAELKIRSPSIQLIKFGAIGLNAIIFSPLLIAADTGSQYGTNITINDGDRI---TGDTA 70 + A L+ + ++ L GA ++ I Q+G +I +D + +G T Sbjct: 10 KAAPLRRTTLAMALGALGAAPAAHADWNNQSIVKTGERQHGIHIQGSDPGGVRTASGTTI 69 Query: 71 DPSGN-LYGVMTPAGNTPGNINLGNDVTVN---VNDASGYAKGIIIQGKNSSLTANRLTV 126 SG G++ N + N + ++D + K L A+ T+ Sbjct: 70 KVSGRQAQGILLE--NPAAELQFRNGSVTSSGQLSDDGIRRFLGTVTVKAGKLVADHATL 127 Query: 127 DVVGQT---SAIGINLIGDYTHADLGTGSTIKSNDDGIIIGHSSTLTATQFTIENSNGIG 183 VG T I + + G+ A + ST++ G+ I + +T + I + G+ Sbjct: 128 ANVGDTWDDDGIALYVAGEQAQASIAD-STLQGAG-GVQIERGANVTVQRSAIVD-GGLH 184 Query: 184 LTINDYGTSVDLGSGSKIKTDGS-TGVYIGGLNGNNANGAARFTATDLTID---VQGYSA 239 + DL + D + T V G + A++LT+D + G A Sbjct: 185 IGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPA----AVSVLGASELTLDGGHITGGRA 240 Query: 240 MGINVQKNSVVDLGTNSTIKTNGDNAHGLWSFGQVSANAL-------TVDVTGAAANGVE 292 G+ + +VV L +TI+ A G G V A+ GV+ Sbjct: 241 AGVAAMQGAVVHL-QRATIRRGDAPAGGAVPGGAVPGGAVPGGFGPGGFGPVLDGWYGVD 299 Query: 293 VRGGTTTIGADSHISSAQGGGLVTSSSDATINFSG---TAAQRNSIFSGGSYGASAQTAT 349 V G + + A S + + + G + A + SG +A N I +GG+ + Q A Sbjct: 300 VSGSSVEL-AQSIVEAPELGAAIRVGRGARVTVSGGSLSAPHGNVIETGGARRFAPQAAP 358 Query: 350 AVINMQNTDITVDRNGSLALGLWALSGGRITGDSLAITGAAGARGIYAMTNSQIDLTSDL 409 I +Q G+ A G L L +TG A A+G T + + Sbjct: 359 LSITLQA--------GAHAQGKALLYRVLPEPVKLTLTGGADAQGDIVATELPSIPGTSI 410 Query: 410 VIDMSTPDQMAIATQHDDGYAASRINASGRMLINGSVLSKGGLINLDMHPGSVWTGSSLS 469 P +A+A+ + WTG++ Sbjct: 411 -----GPLDVALAS------------------------------------QARWTGAT-- 427 Query: 470 DNVNGGKLDVAMNNSVWNVTSNSNLDTLAL-SHSTVDFASHGSTAGTFTTLNVENLSGNS 528 V+ +D N+ W +T NSN+ L L S +VDF + AG F L V L+G+ Sbjct: 428 RAVDSLSID----NATWVMTDNSNVGALRLASDGSVDFQQ-PAEAGRFKVLTVNTLAGSG 482 Query: 529 TFIMRADVVGEGNGVNNRGDLLNISGSSAGNHVLAIRNQGSEATTGNEVLTVVKTTDGAA 588 F M D L + ++G H L +RN GSE + N +L V AA Sbjct: 483 LFRMNV------FADLGLSDKLVVMQDASGQHRLWVRNSGSEPASANTLLLVQTPLGSAA 536 Query: 589 SFSASS---QVELGGYLYDVRKNG-TNWELYASGTVPEPTPNPEPTPAPAQPPIVNPD-P 643 +F+ ++ +V++G Y Y + NG W L + P P P P+P P P QPP P+ P Sbjct: 537 TFTLANKDGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAP 596 Query: 644 TPEPAPTPKPTTTADAGGNYLNVGYL--LNYVENRTLMQRMGDLRNQSKDGNIWLRSYG- 700 P+P + + A+A N VG L Y E+ L +R+G+LR G W R + Sbjct: 597 APQPPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRLNPDAGGAWGRGFAQ 656 Query: 701 -GSLDSFASGKLSGFDMGYSGIQFGGDKRLSDVM-PLYVGLYIDSTHASPDYSG-GDGTA 757 LD+ A + FD +G + G D ++ ++G T ++G G G Sbjct: 657 RQQLDNRAGRR---FDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDRGFTGDGGGHT 713 Query: 758 RSDYMGMYASYMAQNGFYSDLVIKASRQKNSFHVLDSQNNGVNANGTANGMSISLEAGQR 817 S ++G YA+Y+A +GFY D ++ASR +N F V S V +G+ SLEAG+R Sbjct: 714 DSVHVGGYATYIADSGFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGASLEAGRR 773 Query: 818 FNLSPTGYGFYIEPQTQLTYSHQNEMAMKASNGLNIHLNHYESLLGRASMILGYDIT-AG 876 F + G+++EPQ +L A +A+NGL + S+LGR + +G I AG Sbjct: 774 FTHAD---GWFLEPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLEVGKRIELAG 830 Query: 877 NSQLNVYVKTGAIREFSGDTEYLLNDSREKYSFKGNGWNNGVGVSAQYNKQHTFYLEADY 936 Q+ Y+K ++EF G N + +G G+G++A + H+ Y +Y Sbjct: 831 GRQVQPYIKASVLQEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALGRGHSLYASYEY 890 Query: 937 TQGNLFDQK-QVNGGYRFSF 955 ++G + GYR+S+ Sbjct: 891 SKGPKLAMPWTFHAGYRYSW 910
>INTIMIN#Intimin signature. Length = 939 Score = 254 bits (650), Expect = 2e-78 Identities = 120/378 (31%), Positives = 197/378 (52%), Gaps = 21/378 (5%) Query: 32 GEQAKAFALGKVRDALSQQVNQHVESWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDN 91 G+ AK ALG + Q + +++WL +G A V+++ N F GS + +P D+ Sbjct: 184 GDYAKDTALGIAGN----QASSQLQAWLQHYGTAEVNLQSGNN--FDGSSLDFLLPFYDS 237 Query: 92 DRYLTWSQLGLTQQDNGLVSNVGVGQRWARGNWLVGYNTFYDNLQDENLQRAGFGAEAWG 151 ++ L + Q+G D+ +N+G GQR+ ++GYN F D + R G G E W Sbjct: 238 EKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDFSGDNTRLGIGGEYWR 297 Query: 152 EYLRLSANFYQPFAAWHE--QTATQEQRMARGYDLTARMRMPFYQHLNTSVSLEQYFGDR 209 +Y + S N Y + WHE ++R A G+D+ +P Y L + EQY+GD Sbjct: 298 DYFKSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDN 357 Query: 210 VDLFNSGTGYHNPVALSLGLNYTPVPLVTVTAQHKQGESGENQNNLGLNLNYRFGVPLKK 269 V LFNS NP A ++G+NYTP+PLVT+ ++ G EN + Y+F P + Sbjct: 358 VALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQ 417 Query: 270 QLSAGEVAESQSLRGSRYDNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQI 329 Q+ V E ++L GSRYD QRNN LEY+++ L++ + + T ++L + Sbjct: 418 QIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNI-PHDINGTERSTQKIQLIV 476 Query: 330 RSRYGIRQLIWQGDTQILS-----LTPGAQANSAEGWTLIMPDWQNGEGASNHWRLSVVV 384 +S+YG+ +++W D+ + S G+Q SA+ + I+P + +G SN ++++ Sbjct: 477 KSKYGLDRIVWD-DSALRSQGGQIQHSGSQ--SAQDYQAILPAYV--QGGSNVYKVTARA 531 Query: 385 EDNQGQRVSSNEITLTLV 402 D G SSN + LT+ Sbjct: 532 YDRNGN--SSNNVLLTIT 547
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.7 bits (181), Expect = 2e-17 Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 2/117 (1%) Query: 7 ATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQGIELAESLDPDLILLDLNMPGMN 66 ATIL+ DD +RT + Q +S A + SN + D DL++ D+ MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 67 GLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALHQA 123 + L ++++ ++V S N + A ++GA YL K + +L+ + +A Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>PF06580#Sensor histidine kinase Length = 349 Score = 53.3 bits (128), Expect = 1e-09 Identities = 36/172 (20%), Positives = 73/172 (42%), Gaps = 23/172 (13%) Query: 424 PESSRELLSQIRNELNASWAQLRELLTTFRLQLTEPGLRPALEASCEEYSAKFGFPVKLD 483 P +RE+L+ + + S + +LT +++ + S +F ++ + Sbjct: 190 PTKAREMLTSLSELMRYSLRYSNARQVSLADELT------VVDSYLQLASIQFEDRLQFE 243 Query: 484 YQLPPRL----VPSHQAIHLLQIAREALSNALKH-----SQASEVVVTVAQNDNQVKLTV 534 Q+ P + VP L+Q E N +KH Q ++++ +++ V L V Sbjct: 244 NQINPAIMDVQVPPM----LVQTLVE---NGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 535 QDNGCGVPENAIRSNHYGMIIMRDRAQSLRG-DCRVRRRESGGTEVVVTFIP 585 ++ G +N S G+ +R+R Q L G + +++ E G + IP Sbjct: 297 ENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 32.5 bits (74), Expect = 0.004 Identities = 35/166 (21%), Positives = 60/166 (36%), Gaps = 22/166 (13%) Query: 258 IMSLLYLATFGSFIGFSAGFAMLSKTQFPDVQILQYAFFGPFIGALARSA---GGALSDR 314 I+S + L+ + I A A L K + + FFG F S ++ Sbjct: 474 IVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKI 533 Query: 315 LGGTRVTLVNFILMAIFSGLLFLTLPTD----GQGGSFMAFFAVFLALFLTAGLGSGSTF 370 LG T L+ + L+ +LFL LP+ G F+ L +G+T Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTM----------IQLPAGATQ 583 Query: 371 QMISVIFRKLTMDRVKAEGGSDER-----AMREAATGTAAALGFIS 411 + + ++T +K E + E + A + F+S Sbjct: 584 ERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVS 629
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 45.6 bits (108), Expect = 2e-07 Identities = 75/382 (19%), Positives = 138/382 (36%), Gaps = 22/382 (5%) Query: 7 LLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAA---GMLISAYAVGVMVGAPLMTLL 63 L +A+ A GIG M +LP + R + S G+L++ YA+ AP++ L Sbjct: 11 LSTVALDAVGIGLI----MPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 64 LSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVP 123 RR L+ +A + + A AP L + RI+ + G+ + A + Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYI-ADITD 125 Query: 124 KHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRMSFLATAGLGVISMVSLFFSLPKG 183 ++A M + G +G F A A L ++ ++ F LP+ Sbjct: 126 GDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 184 GTGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSI--------THAT 235 G R +++E + + +T V A+F + + V ++ H Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWD 244 Query: 236 PVFVTAMLVLIGVGFSIGN-YLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNEFGAA 294 + L G+ S+ + G +A R ++ + A + A Sbjct: 245 ATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAF 304 Query: 295 ISMVVWGAATFAVVPPLQ-MRVMHVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGL 353 MV+ + +P LQ M V E G +L + +G A+ +A + Sbjct: 305 PIMVLLASGGIG-MPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASI 363 Query: 354 GY--SFVPVTGAIVAGLALLLV 373 + + GA + L L + Sbjct: 364 TTWNGWAWIAGAALYLLCLPAL 385
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 74.9 bits (184), Expect = 8e-17 Identities = 45/188 (23%), Positives = 81/188 (43%), Gaps = 2/188 (1%) Query: 6 RFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLS 65 + L+WL LS L + + I D P ++ + + F+ F+ ++G LS Sbjct: 14 QILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73 Query: 66 DRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVL-RFVQAVGVCAAPVIWQALVTDYYR 124 D+ G K +LL G+ I GS+ + +LL++ RF+Q G A P + +V Y Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIP 133 Query: 125 SQKVNRIFATIMPLVGLSPALAPLLGSWIMVHFSWQAILATLYAITVVMILPIFWLKPTT 184 + + F I +V + + P +G I + W + L + IT++ + + L Sbjct: 134 KENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW-SYLLLIPMITIITVPFLMKLLKKE 192 Query: 185 KARNNSQD 192 D Sbjct: 193 VRIKGHFD 200
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.0 bits (67), Expect = 0.023 Identities = 26/128 (20%), Positives = 45/128 (35%), Gaps = 5/128 (3%) Query: 278 VELTGSVALLDGASMIIGYGAELQQSTITV-QQGGVLILDGSTVKGDSVTFIVGNINLNG 336 V LT S + G + + G S + + + + S V + G+I+LN Sbjct: 819 VNLTESANFVLGKANLFGTIQSRGNSQVRLTENSHWHLTGNSDVH--QLDLANGHIHLNS 876 Query: 337 GKLWLITGAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVNGDIRVEITDASRQ 396 + L V L G G+ T D + V G+ +++ D + + Sbjct: 877 ADN--SNNVTKYNTLTVNSLSGNGSFYYLTDLSNKQGDKVVVTKSATGNFTLQVADKTGE 934 Query: 397 TLCNALKL 404 N L L Sbjct: 935 PNHNELTL 942
>ICENUCLEATIN#Ice nucleation protein signature. Length = 1258 Score = 29.0 bits (64), Expect = 0.026 Identities = 39/163 (23%), Positives = 74/163 (45%), Gaps = 24/163 (14%) Query: 108 TAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRIANTGMRV 167 TAGY + + S SV++ +GER ++ +S++ +AGD S++ Sbjct: 1113 TAGYRSTLISGADSVQM-----------AGERGKLIAGADSTQ--TAGDRSKL--LAGNN 1157 Query: 168 RVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGL 227 T G+R + + D + +A G +++ +G N + A + + S G L Sbjct: 1158 SYLTAGDRSKLTAGNDCILMA--GDRSKLT-AGINSILTAGCRSKLIGSNGST----LTA 1210 Query: 228 GGSAALAYH--DGERVRFAVAIEGENNIRTGVRYRLNEQHQFV 268 G ++ L + DG+R VA G+ I + Y+++E + V Sbjct: 1211 GENSVLIFRCWDGKRYTNVVAKTGKGGIEADMPYQMDEDNNIV 1253
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 4e-24 Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 7 KFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGL 66 LV DD + +R ++ L G++ V + + AG V++D MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYD-VRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 67 ELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAGASGYVVKPF 111 +LL I+ LPVL+++A+ I A++ GA Y+ KPF Sbjct: 64 DLLPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.2 bits (159), Expect = 9e-14 Identities = 35/188 (18%), Positives = 72/188 (38%), Gaps = 23/188 (12%) Query: 1 MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMP 60 M+ +L DD A +R ++ + ++ V + I + D++ DV MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 RMDGLDFLEKLMRLRPMPVVMVSSLTGKGS-EVTLRALELGAIDFVTKPQLGIREGMLAY 119 + D L ++ + RP V+V ++ + + ++A E GA D++ KP + E + Sbjct: 59 DENAFDLLPRIKKARPDLPVLV--MSAQNTFMTAIKASEKGAYDYLPKP-FDLTELIGII 115 Query: 120 SEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQPLP 179 +AE R +K + + +G S E R + + + Sbjct: 116 GRALAEPKRRPSKLEDDSQDGMP-----------------LVGRSAAMQEIYRVLARLMQ 158 Query: 180 LSSPALLI 187 ++ Sbjct: 159 TDLTLMIT 166
>PF06580#Sensor histidine kinase Length = 349 Score = 42.2 bits (99), Expect = 4e-06 Identities = 23/151 (15%), Positives = 49/151 (32%), Gaps = 52/151 (34%) Query: 361 ELDKSLIERIIDPLT--HLVRNSLDHGIELPEKRLAAGKNSVGNLILSAEHQGGNICIEV 418 +++ ++++ + P+ LV N + HGI G ++L G + +EV Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTLEV 296 Query: 419 TDDGAGLNRERILAKAASQGLTVSENMSDDEVAMLIFAPGFSTAEQVTDVSGRGVGMDVV 478 + G+ + G G+ V Sbjct: 297 ENTGSLALKNTK--------------------------------------ESTGTGLQNV 318 Query: 479 KRNIQEMGG---HVEIQSKQGTGTTIRILLP 506 + +Q + G +++ KQG +L+P Sbjct: 319 RERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.009 Identities = 22/93 (23%), Positives = 35/93 (37%), Gaps = 11/93 (11%) Query: 46 LISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKQPNIEE 105 L +SSP A P + G + ++ PGGGDD GE +++ Sbjct: 384 LADVSSPTAAAGGAGGGEPPKKRDPSAG---AGTDPGGPGGGDD-----GEDPFGEWLDD 435 Query: 106 LKKRM---EQSRLRKLRGDLDQLIESDPKLRAL 135 R+ + L+ R L + + S P L Sbjct: 436 EVARLRLRGRWLLKPRRAALIEALRSAPALAGC 468
>PF05844#YopD protein Length = 295 Score = 33.1 bits (75), Expect = 0.001 Identities = 12/28 (42%), Positives = 22/28 (78%), Gaps = 2/28 (7%) Query: 76 MDLLALLYRLMAKSRQMGMFSLERDIEN 103 ++LL +L+R+ K+R++G+ L+RD EN Sbjct: 74 VELLLILFRIAQKARELGV--LQRDNEN 99
>FLAGELLIN#Flagellin signature. Length = 507 Score = 234 bits (599), Expect = 9e-73 Identities = 260/551 (47%), Positives = 311/551 (56%), Gaps = 47/551 (8%) Query: 2 AQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 61 AQVINTNSLSL+TQNN+NK+QS+LSS+IERLSSGLRINSAKDDAAGQAIANRFTSNIKGL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 TQAARNANDGISVAQTTEGALSEINNNLQRIRELTVQASTGTNSDSDLDSIQDEIKSRLD 121 TQA+RNANDGIS+AQTTEGAL+EINNNLQR+REL+VQA+ GTNSDSDL SIQDEI+ RL+ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EIDRVSGQTQFNGVNVLAKDGSMKIQVGANDGQTITIDLKKIDSDTLGLNGFNVNGGGAV 181 EIDRVS QTQFNGV VL++D MKIQVGANDG+TITIDL+KID +LGL+GFNVNG Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEA 180 Query: 182 A---NTAASKADLVAANATVVGNKYTVSAGYDAAKASDLLAGVSDGDTVQATINNGFGTA 238 ++ K V NKY V A V D V A N T Sbjct: 181 TVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAA-NGQLTTD 239 Query: 239 ASATNYKYDSASKSYSFDTTTASAADVQKYLTPGVGDTAKGTITIDGSAQDVQISSDGKI 298 + N D + S T + A GDT +GK+ Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKV 299 Query: 299 TASNGDKLYIDTTGRLTKNGSGASLTEASLSTLAANNTKATTIDIGGTSISFTGNSTTPD 358 + T NG +LT A ++ AAN AT S T D Sbjct: 300 ST--------------TINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFD 345 Query: 359 TITYSVTGAKVDQAAFDKAVSTSGNNVDFTTAGYSVNGTTGAVTKGVDSVYVDNNEALTT 418 T + + D A + S V+ + G + Sbjct: 346 DKTKNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLA---------------- 389 Query: 419 SDTVDFYLQDDGSVTNGSGKAVYKDADGKLTTDAETKAATTADPLKALDEAISSIDKFRS 478 + DA +TA+PL ++D A+S +D RS Sbjct: 390 -------------GKTMFIDKTASGVSTLINEDAAAAKKSTANPLASIDSALSKVDAVRS 436 Query: 479 SLGAVQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLAKAN 538 SLGA+QNR DSA+TNL NT TNL+ A+SRI+DADYATEVSNMSKAQI+QQAG SVLA+AN Sbjct: 437 SLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKAQILQQAGTSVLAQAN 496 Query: 539 QVPQQVLSLLQ 549 QVPQ VLSLL+ Sbjct: 497 QVPQNVLSLLR 507
>TYPE3OMBPROT#Type III secretion system outer membrane B protein family signature. Length = 538 Score = 32.0 bits (72), Expect = 0.005 Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 2/72 (2%) Query: 214 NGMEVSVAAQNAQLTVNNVAIENSSNTISDALENITLNLNDVTTGNQTLTITQDTSKVQT 273 N E +VAA+N + + A+ + +S AL T++L V+T LT T T ++ Sbjct: 236 NSSERAVAARNKAEELVSAALYSRPELLSQALSGKTVDLKIVSTS--LLTPTSLTGGEES 293 Query: 274 AIKDWVNAYNSL 285 +KD VNA L Sbjct: 294 MLKDQVNALKGL 305
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 28.9 bits (64), Expect = 0.022 Identities = 41/160 (25%), Positives = 67/160 (41%), Gaps = 21/160 (13%) Query: 208 VKLSIQGNLTAPQSCKINQGDVIKVNFGFINGQKFTTRNAMPDGFTPVDFDITYDCGDTS 267 V+++I+GN+ P C IN G I V+FG IN + V +I+ C S Sbjct: 21 VQINIRGNVYIP-PCTINNGQNIVVDFGNINPEHVDNSRG------EVTKNISISCPYKS 73 Query: 268 KIKNSLQMRIDGTTGVVDQYNLVARRRSSDNVPDVGIRIENLGGGVANIPFQNG------ 321 SL +++ G T V Q N++A N+ GI + G + NG Sbjct: 74 ---GSLWIKVTGNTMGVGQNNVLA-----TNITHFGIALYQGKGMSTPLTLGNGSGNGYR 125 Query: 322 ILPVDPSGHGTVNMRAWPVNLVGGELETGKFQGTATITVM 361 + + T + P G L G F+ TA+++++ Sbjct: 126 VTAGLDTARSTFTFTSVPFRNGSGILNGGDFRTTASMSMI 165
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.4 bits (68), Expect = 0.029 Identities = 41/266 (15%), Positives = 83/266 (31%), Gaps = 15/266 (5%) Query: 277 QQGFEAAKNIGTQPVAAQVAAAPAADVAEQPQPQTADSVASPAQASVSDLTGDQPAAQPV 336 Q G E + T+ E + Q V S QP A+P Sbjct: 1087 QSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPA 1146 Query: 337 PVSAPATSTAAVSAPANPSAELKIYDTSSQPLSQILSQVQQDGASIVVGPLLKNNVEELL 396 + P + + N +A+ + + S + V + +++N Sbjct: 1147 RENDPTVNIKEPQSQTNTTAD--TEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTP 1204 Query: 397 KSNTPLNVLALNQPENIENRVNICYFALSPEDEARDAARHIRDQGKQAPLVLIPR---SA 453 + P + +R ++ + E A D+ A L + Sbjct: 1205 ATTQPTVNSESSNKPKNRHRRSVRSVPHNVE----PATTSSNDRSTVALCDLTSTNTNAV 1260 Query: 454 LGDRVANAFAQEWQKLGGGTVLQQKFGSTSELRAGVNGGSGIALTGSPITPRATTDSGMT 513 L D A A ++ L G + Q S+L G + ++ + + ++ Sbjct: 1261 LSDARAKA---QFVALNVGKAVSQHI---SQLEMNNEGQYNVWVSNTSMNKNYSSSQYRR 1314 Query: 514 TNNPTLQTTPTDDQFTNNGGRVDAVY 539 ++ + QT DQ +N ++ V+ Sbjct: 1315 FSSKSTQTQLGWDQTISNNVQLGGVF 1340
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 27.6 bits (61), Expect = 0.036 Identities = 26/111 (23%), Positives = 44/111 (39%), Gaps = 22/111 (19%) Query: 42 NKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIA-------NDRL 94 K+L GN + A T + IA + V AI+ D+ Sbjct: 277 TKVL--GNVGKGISQYIIAQRAAQGLSTSAAAAGLIA----SAVTLAISPLSFLSIADKF 330 Query: 95 HD----EVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVA 141 E Y+++ + LG+ GD LLA + A++A++T T++A Sbjct: 331 KRANKIEEYSQRFKKLGYDGDSLLAAFHKETG-----AIDASLTTISTVLA 376
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.0 bits (65), Expect = 0.013 Identities = 8/22 (36%), Positives = 13/22 (59%) Query: 19 VLITGATGLVGGHLLRMLINEP 40 L+TGA G +G H+ + L+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG 24
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 52.7 bits (126), Expect = 8e-10 Identities = 31/160 (19%), Positives = 59/160 (36%), Gaps = 26/160 (16%) Query: 77 RTLGSGVIMDQRGYIITNKHVINDADQIIVALQ------------DGRVFEALLVGSDSL 124 + SGV++ + ++TNKHV++ AL+ +G + Sbjct: 101 TFIASGVVVG-KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGE 159 Query: 125 TDLAVLKI-------NATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATG 177 DLA++K + + ++ + + G P + T + G Sbjct: 160 GDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGD-KPVATMW--ESKG 216 Query: 178 RIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINT 217 +I + +Q D S GNSG + N E++GI+ Sbjct: 217 KI---TYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHW 253
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.1 bits (62), Expect = 0.045 Identities = 37/167 (22%), Positives = 61/167 (36%), Gaps = 27/167 (16%) Query: 3 VAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGED 62 + GAA GIG+A+A L G+ ++ D P V S A + F + Sbjct: 11 AFITGAAQGIGEAVARTL---ASQGAHIAAVDYNP-EKLEKVVSSLKAEARHAEAFPADV 66 Query: 63 ATPA------------LEGADVVLISAGVARK------PGMDRSDLFNVNAGIVKNLVQQ 104 A + D+++ AGV R + F+VN+ V N + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 105 VAKNCPK----ACIGIITNPVNTT-VAIAAEVLKKAGVYDKNKLFGV 146 V+K + + + +NP ++AA KA K G+ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGL 173
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 169 bits (430), Expect = 4e-57 Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 5/141 (3%) Query: 15 KALLKEEKFSSQGEIVAALQEQGFDNINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELG 74 + ++ + +Q E+V L++ G+ N+ Q+ VSR + + V+ Y LPA+ Sbjct: 11 REIITANEIETQDELVDILKKDGY-NVTQATVSRDIKELHLVKVPTNNGSYKYSLPADQR 69 Query: 75 VPTTSSPLKNLV---LDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTI 131 S ++L+ + ID ++V+ T PG AQ I L+D+L E I+GTI GDDTI Sbjct: 70 FNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEE-IMGTICGDDTI 128 Query: 132 FTTPANGFTVKDLYEAILELF 152 K + + ILEL Sbjct: 129 LIICRTHDDTKVVQKKILELL 149
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 53.3 bits (128), Expect = 5e-10 Identities = 28/163 (17%), Positives = 59/163 (36%), Gaps = 16/163 (9%) Query: 6 RKFSRTAITVVLVILAFIAIFNAWVYYTE----SPWTRDARFSADVVAIAPDVSGLITQV 61 SR V I+ F+ I + + S I P + ++ ++ Sbjct: 51 TPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEI 110 Query: 62 NVHDNQLVKKGQILFTIDQPR-------YQKALEEAQADVAYYQVLAQEKRQEAGRRNRL 114 V + + V+KG +L + Q +L +A+ + YQ+L++ E + L Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRS--IELNKLPEL 168 Query: 115 GVQAMSREEIDQANNVL---QTVLHQLAKAQATRDLAKLDLER 154 + + VL + Q + Q + +L+L++ Sbjct: 169 KLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDK 211 Score = 51.4 bits (123), Expect = 2e-09 Identities = 28/147 (19%), Positives = 54/147 (36%), Gaps = 15/147 (10%) Query: 100 LAQEKRQEAGRRNRLGVQ-AMSREEIDQANNVLQT-VLHQLAKAQAT-------RDLAKL 150 E R + ++ + ++EE + + +L +L + + Sbjct: 264 AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEE 323 Query: 151 DLERTVIRAPADGWVTNLNVYT-GEFITRGSTAVALVKQNSFY-VLAYMEETKLEGVRPG 208 + +VIRAP V L V+T G +T T + +V ++ V A ++ + + G Sbjct: 324 RQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVG 383 Query: 209 YRAEIT----PLGSNKVLKGTVDSVAA 231 A I P L G V ++ Sbjct: 384 QNAIIKVEAFPYTRYGYLVGKVKNINL 410
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.0 bits (65), Expect = 0.021 Identities = 14/62 (22%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 160 ASSVEDLVTQTLEFTIEEVNADRNV-SNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI 218 A +V+D VTQ +E + ++ + S + + + L + D A QV ++L + Sbjct: 54 AQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQL 113 Query: 219 SK 220 + Sbjct: 114 AT 115
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 133 bits (337), Expect = 2e-40 Identities = 80/226 (35%), Positives = 124/226 (54%), Gaps = 9/226 (3%) Query: 28 AAKPATTADSKASFKNDDQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAF 87 A A A S D K +Y++GA LG K + GI ++ D L G+QD Sbjct: 14 AMSTAMAATDATSLTTDKDKLSYSIGADLG-------KNFKNQGIDINPDVLAKGMQDGM 66 Query: 88 A-DKSKLSDQEIEQTLQAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSST 146 + + L++++++ L F+ + + A+ K A +N+AKG + + G+ + Sbjct: 67 SGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPGIVVLPS 126 Query: 147 GLVYQVVEAGKGEAPKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGL 206 GL Y++++AG G P SDTV V Y GTLIDG FD++ G+P +F++ VIPGWTE L Sbjct: 127 GLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEAL 186 Query: 207 KNIKKGGKIKLVIPPELAYGKAGVPG-IPPNSTLVFDVELLDVKPA 251 + + G ++ +P +LAYG V G I PN TL+F + L+ VK A Sbjct: 187 QLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVKKA 232
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 31.9 bits (72), Expect = 0.001 Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 16/135 (11%) Query: 11 YAHPESQDSVANRVLLKPATQLSNVTVHDLYAHYPDFFIDIPREQALLREHEVIVFQH-- 68 Y P + D N+V P + + +HD+ ++ D F L + + Sbjct: 9 YQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCV 68 Query: 69 ----PLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAGKYWRNVITTGEPESA------Y 118 P+ + P DR L F GPG N +G Y +IT PE + Sbjct: 69 QLGIPVVYTAQPGSQNP-DDRALLTDFW-GPGLN--SGPYEEKIITELAPEDDDLVLTKW 124 Query: 119 RYDALNRYPMSDVLR 133 RY A R + +++R Sbjct: 125 RYSAFKRTNLLEMMR 139
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.7 bits (74), Expect = 0.005 Identities = 28/152 (18%), Positives = 54/152 (35%), Gaps = 22/152 (14%) Query: 504 KVEPFDGDLEDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKE 563 + D + ++ E + + ++ R+ +R R + L E Sbjct: 272 AMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAE 331 Query: 564 IARLEKEME---------------------KLNAQLAQAEEKLGDSELYDQSRKAELTAC 602 +LE++ + +L A+ + EE+ SE QS + +L A Sbjct: 332 HQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDAS 391 Query: 603 LQQQASAKSGLEECEMAWLEAQEQLEQMLLEG 634 + + + LEE L A E+L + L E Sbjct: 392 REAKKQVEKALEEANSK-LAALEKLNKELEES 422 Score = 32.0 bits (72), Expect = 0.008 Identities = 13/125 (10%), Positives = 39/125 (31%), Gaps = 7/125 (5%) Query: 513 EDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKEIARLEKEME 572 + + ++ + E A A + D ++ + +++ Sbjct: 127 KALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFST-------ADSAKIK 179 Query: 573 KLNAQLAQAEEKLGDSELYDQSRKAELTACLQQQASAKSGLEECEMAWLEAQEQLEQMLL 632 L A+ A E + + E + TA + + ++ + ++ LE + Sbjct: 180 TLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMN 239 Query: 633 EGQSN 637 ++ Sbjct: 240 FSTAD 244
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 37.2 bits (86), Expect = 1e-05 Identities = 21/92 (22%), Positives = 33/92 (35%), Gaps = 16/92 (17%) Query: 55 VACIDGDVVGHLTIDVQQRPRRSHVADFGICVDSRWKNRGVASALMREMIE------MCD 108 + ++ + +G + I + + D + D R K GV +AL+ + IE C Sbjct: 69 LYYLENNCIGRIKIR-SNWNGYALIEDIAVAKDYRKK--GVGTALLHKAIEWAKENHFCG 125 Query: 109 NWLRVDRIELTVFVDNAPAIKVYKKFGFEIEG 140 L I N A Y K F I Sbjct: 126 LMLETQDI-------NISACHFYAKHHFIIGA 150
>NAFLGMOTY#Sodium-type flagellar protein MotY precursor signature. Length = 293 Score = 31.6 bits (71), Expect = 0.007 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 17/82 (20%) Query: 275 RTPISGDYRGYQVYSMPPPSSGGIHIVQILNI--LENFDMKKYGF-GSADAMQIMAEAEK 331 R P+ G+ R + SMPPP G H +I N+ + FD G+ G A I++E EK Sbjct: 77 RRPM-GETRNVSLISMPPPWRPGEHADRITNLKFFKQFD----GYVGGQTAWGILSELEK 131 Query: 332 YAYADRSEYLGDPDFVKVPWQA 353 Y P F WQ+ Sbjct: 132 GRY---------PTFSYQDWQS 144
>PF04619#Dr-family adhesin Length = 160 Score = 28.4 bits (63), Expect = 0.017 Identities = 12/60 (20%), Positives = 22/60 (36%), Gaps = 4/60 (6%) Query: 29 VGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQD----LLRVDAGSW 84 +G ++ D + G+ FL+ D+N ++ W + D GSW Sbjct: 70 LGCDARQVALKADTDNFEQGKFFLISDNNRDKLYVNIRPTDNSAWTTDNGVFYKNDVGSW 129
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.9 bits (101), Expect = 1e-06 Identities = 47/275 (17%), Positives = 94/275 (34%), Gaps = 32/275 (11%) Query: 44 PVSQVAFSFGLLSLGLAIS----SSVAGKLQERFGVKRVTVASGILLGLGFFLTAHSNNL 99 + V +G+L A+ + V G L +RFG + V + S + + + A + L Sbjct: 37 HSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFL 96 Query: 100 MMLWLS---AGVLVGLADGAGYLL----TLSNCVKWFPERKGLISAFAIGSYGLGSLGFK 152 +L++ AG+ AG + + F + LG Sbjct: 97 WVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGG---- 152 Query: 153 FIDTQLLETVGLEKTFVIWGAIALVMIVFGATLMKDAPKQEVKTSNGVVEKDYTLAESMR 212 L+ F A+ + + G L+ ++ K E + R Sbjct: 153 -----LMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWAR 207 Query: 213 --KPQYWMLAVMFLTACMSG----LYVIGVAKDIAQSLAHLDVVSAANAVTVISIAN-LS 265 ++AV F+ + L+VI + H D + ++ I + L+ Sbjct: 208 GMTVVAALMAVFFIMQLVGQVPAALWVI-----FGEDRFHWDATTIGISLAAFGILHSLA 262 Query: 266 GRLVLGILSDKIARIRVITIGQVISLVGMAALLFA 300 ++ G ++ ++ R + +G + G L FA Sbjct: 263 QAMITGPVAARLGERRALMLGMIADGTGYILLAFA 297 Score = 36.0 bits (83), Expect = 2e-04 Identities = 37/155 (23%), Positives = 64/155 (41%), Gaps = 9/155 (5%) Query: 241 AQSLAHLDVVSAANAVTVISIANLSGRLVLGILSDKIARIRVITIGQVISLVGMAALLFA 300 AH ++ A A+ + A + G L SD+ R V+ + + V A + A Sbjct: 39 NDVTAHYGILLALYALMQFACAPVLGAL-----SDRFGRRPVLLVSLAGAAVDYAIMATA 93 Query: 301 PLNAVTFFAAIACVAFNFGGTITVFPSLVSEFFGLNNLAKNYGVIYLGFGIGSIFGSIIA 360 P V + I VA G T V + +++ + A+++G + FG G + G ++ Sbjct: 94 PFLWVLYIGRI--VAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLG 151 Query: 361 SLFGGF--YVTFYVIFALLILSLALSTTIRQPEQK 393 L GGF + F+ AL L+ + K Sbjct: 152 GLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHK 186
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 27.8 bits (62), Expect = 0.039 Identities = 19/90 (21%), Positives = 37/90 (41%), Gaps = 13/90 (14%) Query: 119 SMYNEFGDSTTTLTDPLWHASVSSLGWRVDSRLGDLRPWAQISYNQQFGENIWKAQSGLS 178 S+ + D+ + H S + + + R G++ P ++SY F + Sbjct: 228 SVAVQQQDAKLV-EENYSHNSQTEVAATLAYRFGNVTP--RVSYAHGFKGSF-------- 276 Query: 179 RMTATNQNGNWLDVTVGADMLLNQNIAAYA 208 ATN N ++ V VGA+ ++ +A Sbjct: 277 --DATNYNNDYDQVVVGAEYDFSKRTSALV 304
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.9 bits (80), Expect = 5e-05 Identities = 16/52 (30%), Positives = 22/52 (42%), Gaps = 5/52 (9%) Query: 76 VAPKAVRRGIGKALMQYV-----QQRYPHLMLEVYQKNQPAIDFYRAQGFHI 122 VA ++G+G AL+ + + LMLE N A FY F I Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 111 bits (280), Expect = 1e-31 Identities = 40/122 (32%), Positives = 61/122 (50%), Gaps = 11/122 (9%) Query: 97 LNMPNNVTFDSSSAPLKPAGANTLTGVAMVLKEY--PKTAVNVIGYTDSTGGHDLNMRLS 154 + ++V F+ + A LKP G L + L +V V+GYTD G N LS Sbjct: 215 FTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLS 274 Query: 155 QQRADSVASALITQGVDASRIRTQGLGPANPIASNSTAEGK---------AQNRRVEITL 205 ++RA SV LI++G+ A +I +G+G +NP+ N+ K A +RRVEI + Sbjct: 275 ERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334 Query: 206 SP 207 Sbjct: 335 KG 336
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 120 bits (302), Expect = 2e-39 Identities = 50/89 (56%), Positives = 66/89 (74%) Query: 2 NKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQLVGFGTFKVNHRAERTGR 61 NK LI +AE EL+K + AA+++ +A++ L +G+ VQL+GFG F+V RA R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEIKIAAANVPAFVSGKALKDAVK 90 NPQTG+EIKI A+ VPAF +GKALKDAVK Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>PF06580#Sensor histidine kinase Length = 349 Score = 36.4 bits (84), Expect = 2e-04 Identities = 49/262 (18%), Positives = 104/262 (39%), Gaps = 43/262 (16%) Query: 197 ILFALATVLLA-SVLSFFW-YRRYLRSRQLLQDEMKRKEKLVALGHLAAGV-AHEIRNPL 253 I+F + V S+L F W + + + ++ Q +M + L L A + H + N L Sbjct: 120 IIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNAL 179 Query: 254 SSIKGLAKYFAERAPAGGEAHQLAQVM---AKEADRLNRVVSELLELVKPTHLALQAVDL 310 ++I+ L +A L+++M + ++ +++ L +V ++L L ++ Sbjct: 180 NNIRALILEDPTKAREM--LTSLSELMRYSLRYSNARQVSLADELTVVD-SYLQLASIQF 236 Query: 311 NTLINHSLQLVSQDANSREIQLRFTANDTLPEIQADPDRLTQVLL-NLYLNAIQAIGQHG 369 + Q+ + ++Q+ P L Q L+ N + I + Q G Sbjct: 237 EDRLQFENQI---NPAIMDVQV--------------PPMLVQTLVENGIKHGIAQLPQGG 279 Query: 370 VISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGG 429 I + ++ V + V ++G + E TG GL V ++ G Sbjct: 280 KILLKGTKDNGTVTLEVENTGSLALKNT------------KESTGTGLQNVRERLQMLYG 327 Query: 430 ---TIQVASQEGKGSTFTLWLP 448 I+++ ++GK + +P Sbjct: 328 TEAQIKLSEKQGKV-NAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 525 bits (1355), Expect = 0.0 Identities = 183/468 (39%), Positives = 253/468 (54%), Gaps = 35/468 (7%) Query: 8 ILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQVREQVFDLVLCDVRMAEMDGIAT 67 ILV DDD + T+L L GY+V + ++ + DLV+ DV M + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 68 LKEIKALNPAIPVLIMTAYSSVETAVEALKTGAQDYLIKPLDFDNLQATLEKALAHTHSI 127 L IK P +PVL+M+A ++ TA++A + GA DYL KP D L + +ALA Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 128 DAETPAVTASQFGMVGKSPAMQHLLSEIALVAPSEATVLIHGDSGTGKELVARAIHASSA 187 ++ + +VG+S AMQ + +A + ++ T++I G+SGTGKELVARA+H Sbjct: 126 PSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGK 185 Query: 188 RSEKPLVTLNCAALNESLLESELFGHEKGAFTGADKRREGRFVEADGGTLFLDEIGDISP 247 R P V +N AA+ L+ESELFGHEKGAFTGA R GRF +A+GGTLFLDEIGD+ Sbjct: 186 RRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPM 245 Query: 248 MMQVRLLRAIQEREVQRVGSNQTISVDVRLIAATHRDLAAEVNAGRFRQDLYYRLNVVAI 307 Q RLLR +Q+ E VG I DVR++AAT++DL +N G FR+DLYYRLNVV + Sbjct: 246 DAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPL 305 Query: 308 EVPSLRQRREDIPLLAGHFLQRFAERNRKAVKGFTPQAMDLLIHYDWPGNIRELENAVER 367 +P LR R EDIP L HF+Q+ + VK F +A++L+ + WPGN+RELEN V R Sbjct: 306 RLPPLRDRAEDIPDLVRHFVQQAEKEGLD-VKRFDQEALELMKAHPWPGNVRELENLVRR 364 Query: 368 AVVLLTGEYISERELPLAIASTPIPLGQSQDIQP-------------------------- 401 L + I+ + + S + Sbjct: 365 LTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALP 424 Query: 402 --------LVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR 441 L E+E +ILAAL T GN+ +AA LG+ R TL K+ Sbjct: 425 PSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 32.3 bits (73), Expect = 0.004 Identities = 14/58 (24%), Positives = 23/58 (39%) Query: 289 ETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIASFQQQLSDMGYK 346 ET+ PD+ L A P L Y + N D +T + + QL+++ Sbjct: 544 ETTKPDMTLKEALKIAFGFNEPNGNLQYQGKDITEFDFNFDQQTSQNIKNQLAELNAT 601
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 34.1 bits (78), Expect = 0.004 Identities = 20/87 (22%), Positives = 37/87 (42%), Gaps = 17/87 (19%) Query: 343 SGLEPLNIGDDSLFVNVGERTN---VTGSA----KFKRLIKEEKYSEALDVARQQVENGA 395 +P+ D ++ + +TN VT + +R+I + LD+ R QV A Sbjct: 298 QAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQ------LDIRRPQVLVEA 351 Query: 396 QIIDINMDEGMLDAEAAMVRFLNLIAG 422 I ++ D L+ +++ N AG Sbjct: 352 IIAEVQ-DADGLNLG---IQWANKNAG 374
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 115 bits (289), Expect = 5e-33 Identities = 79/272 (29%), Positives = 128/272 (47%), Gaps = 27/272 (9%) Query: 7 LQDKIIIVTGGASGIGLAIVEELLAQGANVQMVDIHG-------GDGQYEGHKGYQFWPT 59 ++ KI +TG A GIG A+ L +QGA++ VD + + E F P Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF-PA 64 Query: 60 DISSTKEVNHTVAEIIQRFGRIDGLVNNAGVNFPRLLVDEKAPAGQYELNEAAFEKMVNI 119 D+ + ++ A I + G ID LVN AGV P L+ + L++ +E ++ Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLI---------HSLSDEEWEATFSV 115 Query: 120 NQKGVFLMSQAVARQMVKQHDGVIVNVSSESGLEGSEGQSCYAATKAALNSFTRSWSKEL 179 N GVF S++V++ M+ + G IV V S + YA++KAA FT+ EL Sbjct: 116 NSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLEL 175 Query: 180 GKHGIRVVGIAPGILEKTGLRTPEYEEALAWTRNITVEQLREGYT---KNAIPIGRAGRL 236 ++ IR ++PG E + W EQ+ +G K IP+ + + Sbjct: 176 AEYNIRCNIVSPGSTETDMQWS-------LWADENGAEQVIKGSLETFKTGIPLKKLAKP 228 Query: 237 AEVADFVCYLLSERASYITGVTTNIAGGKTRG 268 +++AD V +L+S +A +IT + GG T G Sbjct: 229 SDIADAVLFLVSGQAGHITMHNLCVDGGATLG 260
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.6 bits (64), Expect = 0.033 Identities = 6/21 (28%), Positives = 12/21 (57%) Query: 24 QAQIARELGIYRTTISRLLKR 44 Q + A LG+ R T+ + ++ Sbjct: 452 QIKAADLLGLNRNTLRKKIRE 472
>PF06580#Sensor histidine kinase Length = 349 Score = 41.0 bits (96), Expect = 8e-06 Identities = 21/99 (21%), Positives = 38/99 (38%), Gaps = 18/99 (18%) Query: 442 LIENALE-ALGP-EPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSE 499 L+EN ++ + GG+I + +G + EV + G + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN------------TKES 310 Query: 500 RGVGLALVKQQVENLGG---SIAVESEPGIFTQFFVQIP 535 G GL V+++++ L G I + + G V IP Sbjct: 311 TGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 71.4 bits (175), Expect = 2e-16 Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 4/109 (3%) Query: 4 VLIIDDDAMVAELNRRYVAQIPGFQCCGTASTLEKAKEIIFNSDAPIDLILLDIYMQKEN 63 +L+ DDDA + + + +++ G+ S I + DL++ D+ M EN Sbjct: 6 ILVADDDAAIRTVLNQALSRA-GYDVR-ITSNAATLWRWI--AAGDGDLVVTDVVMPDEN 61 Query: 64 GLDLLPVLHNARCKSDVIVISSAADAATIKDSLHYGVVDYLIKPFQASR 112 DLLP + AR V+V+S+ T + G DYL KPF + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTE 110
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 90.7 bits (225), Expect = 2e-23 Identities = 40/121 (33%), Positives = 59/121 (48%) Query: 2 KILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEDGHYSLVVLDLGLPDEDGLH 61 IL+ +DD + L A GY + A + + G LVV D+ +PDE+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 FLARIRQKKYTLPVLILTARDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRRHNN 121 L RI++ + LPVL+++A++T I + GA DYL KPF L EL I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 Q 122 + Sbjct: 125 R 125
>PF06580#Sensor histidine kinase Length = 349 Score = 36.8 bits (85), Expect = 1e-04 Identities = 40/182 (21%), Positives = 80/182 (43%), Gaps = 34/182 (18%) Query: 184 ARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDV-ILPSYDELSTML--DQRQQTLL 240 + +M+ S+S+L++ S N + V L +++ ++ SY +L+++ D+ Q Sbjct: 191 TKAREMLTSLSELMR-----YSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 241 LPESAADITVQGDATLLRMLLRNLVENAHRY----SPQGSNIMIKLQEDGGAV-MAVEDE 295 + + D+ V ML++ LVEN ++ PQG I++K +D G V + VE+ Sbjct: 246 INPAIMDVQV------PPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENT 299 Query: 296 GPGIDESKCGELSKAFVRMDSRYGGIGLGLSIV-SRITQLHHGQFFLQNRQETSGTRAWV 354 G + + G GL V R+ L+ + ++ ++ A V Sbjct: 300 GSLA--------------LKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 355 RL 356 + Sbjct: 346 LI 347
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.9 bits (101), Expect = 2e-06 Identities = 57/290 (19%), Positives = 105/290 (36%), Gaps = 55/290 (18%) Query: 85 FFGMLGDKYGRQKILAITIVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGE 144 G L D++GR+ +L +++ ++ + P +W +L I ++ G + G Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPF-----LW---VLYIGRIVAGIT-GAT 112 Query: 145 YTGASIFVAEYSPDRKR----GFMGSWLDFGSIAGFVLGAGVVVLISTIVGEANFLDWGW 200 A ++A+ + +R GFM + FG +AG VLG G++ S Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLG-GLMGGFSP------------ 159 Query: 201 RIPFFIALPLGIIGLYLRHALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKYWRS 260 PFF A L + L K E+ P SF+ W Sbjct: 160 HAPFFAAAALNGLNFLTGCFLLPESH------KGERRPLRREALNPLASFR------WAR 207 Query: 261 LLTCIGLVIATNVTYYML----LTYMPSYLSHNLHYS-EDHGVLIIIAIMIGMLFVQPVM 315 +T + ++A ++ + H+ G+ + ++ L + Sbjct: 208 GMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMIT 267 Query: 316 GLLSDRFGRRPFVLLG----SVALFVLA--------IPAFILINSNVIGL 353 G ++ R G R ++LG +LA P +L+ S IG+ Sbjct: 268 GPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGM 317 Score = 41.0 bits (96), Expect = 8e-06 Identities = 39/164 (23%), Positives = 73/164 (44%), Gaps = 16/164 (9%) Query: 286 LSHNLHYSEDHGVLI-IIAIMIGMLFVQPVMGLLSDRFGRRPFVLLGSVALFVLAIPAFI 344 L H+ + +G+L+ + A+M PV+G LSDRFGRRP +L+ L A+ I Sbjct: 35 LVHSNDVTAHYGILLALYALM--QFACAPVLGALSDRFGRRPVLLVS---LAGAAVDYAI 89 Query: 345 LINSNVIGLIFAGLLMLAVILNCFMGVMASTLPAMFPTHIR---YSALAAAFNISVLVAG 401 + + + +++ G ++A I V + + + R + ++A F +VAG Sbjct: 90 MATAPFLWVLYIG-RIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFG-MVAG 147 Query: 402 LTPTLAAWLVESSQNLMMPAYYLMVVAVIGLITG-VTMKETANR 444 P L + S + P + + + +TG + E+ Sbjct: 148 --PVLGGLMGGFSPH--APFFAAAALNGLNFLTGCFLLPESHKG 187
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.019 Identities = 12/22 (54%), Positives = 13/22 (59%) Query: 32 MVALLGPSGSGKSTLLRHLSGL 53 V L G G GKSTL+ L GL Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL 619
>PF05272#Virulence-associated E family protein Length = 892 Score = 34.7 bits (79), Expect = 6e-04 Identities = 13/35 (37%), Positives = 18/35 (51%) Query: 32 VVFVGPSGCGKSTLLRMIAGLETITSGDLFIGEKR 66 VV G G GKSTL+ + GL+ + IG + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGK 633
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 755 bits (1951), Expect = 0.0 Identities = 395/396 (99%), Positives = 395/396 (99%) Query: 1 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK 60 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK Sbjct: 1 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK 60 Query: 61 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW 120 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW Sbjct: 61 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW 120 Query: 121 DAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP 180 DAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP Sbjct: 121 DAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP 180 Query: 181 YFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE 240 YFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE Sbjct: 181 YFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE 240 Query: 241 AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSTGINAASPNKE 300 AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLS GINAASPNKE Sbjct: 241 AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKE 300 Query: 301 LAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIP 360 LAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIP Sbjct: 301 LAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIP 360 Query: 361 QMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK 396 QMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK Sbjct: 361 QMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK 396
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 31.1 bits (70), Expect = 0.012 Identities = 22/124 (17%), Positives = 43/124 (34%), Gaps = 21/124 (16%) Query: 128 GDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNRQALSDIT 187 ++WQ+ T DA L+L T + L+ + A+ ++ Sbjct: 367 NNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPV---SDAIVNMD 423 Query: 188 AILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNNQ--------IGFYQS 239 ++ D K+ M+S GD N Q+ + + N++ Y S Sbjct: 424 VLITDEAKIAMAS----------EEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYAS 473 Query: 240 ITAD 243 + +D Sbjct: 474 LVSD 477
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.0 bits (83), Expect = 3e-04 Identities = 20/87 (22%), Positives = 42/87 (48%), Gaps = 3/87 (3%) Query: 279 VIGVMLSIFQQFVGINVVLYYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIMT--- 335 +I ++ ++ VGI +++ P + + L S D+ I++ + L A + Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 336 VDKFGRKPLQIIGALGMAIGMFSLGTA 362 D+FGR+P+ ++ G A+ + TA Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATA 93
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 30.8 bits (69), Expect = 0.006 Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 3/95 (3%) Query: 20 AAGTVKVFSNGSSEAKTLTGAEHLIDLVGQPRLANSWWPGAVISEELATAAALRQQQALL 79 A + + + LT + L D+V + N+ + A AA++ + L Sbjct: 73 AKAAAEAQAKAKANRDALT--QRLKDIVNEALRHNASRTPSATELAHANNAAMQAEDERL 130 Query: 80 TRLAEQGADSSTDDAAAINALRQQIQALKVTGRQK 114 RLA+ + + AA A ++ Q K R+K Sbjct: 131 -RLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREK 164
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 29.2 bits (65), Expect = 0.014 Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 4/45 (8%) Query: 145 PLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLW 189 P +V GIA G V T+ GL W ++ N D + +W Sbjct: 42 PAIVG-GIATGAAVGTVSGLLGWGLKQAEEAN---KTPDKPDKVW 82
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.8 bits (215), Expect = 6e-22 Identities = 33/139 (23%), Positives = 60/139 (43%) Query: 1 MQRETVWLVEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKARQQVPDVMILDVGLPDI 60 M T+ + +D+ I L L + G+ V + + D+++ DV +PD Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 SGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYVAKPFSPREVCARVRTLLR 120 + F+L ++ P LPVL ++A++ + + E GA DY+ KPF E+ + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 RVKKFSTPSPVIRIGHFEL 139 K+ + L Sbjct: 121 EPKRRPSKLEDDSQDGMPL 139
>PF06580#Sensor histidine kinase Length = 349 Score = 32.9 bits (75), Expect = 0.003 Identities = 47/207 (22%), Positives = 80/207 (38%), Gaps = 51/207 (24%) Query: 298 LTQNARMQAL---------VETL--LRQARLENRQEVVLTAVDVAALFR---RVSEARTV 343 + Q A++ AL L +R LE+ + ++ L R R S AR V Sbjct: 157 MAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQV 216 Query: 344 QLAE--KNITLHVM--------PTEVNVAAEPALLDQALGNLL-----DNA----IDFTP 384 LA+ + ++ + PA++D + +L +N I P Sbjct: 217 SLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLP 276 Query: 385 ESGCITLSAEVDQEHVTLKVLDTGSGIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSE 444 + G I L D VTL+V +TGS N ++S+G GL V E Sbjct: 277 QGGKILLKGTKDNGTVTLEVENTGSLALK----------------NTKESTGTGLQNVRE 320 Query: 445 -VARLFNGEVTLR-NVQEGGVLASLRL 469 + L+ E ++ + ++G V A + + Sbjct: 321 RLQMLYGTEAQIKLSEKQGKVNAMVLI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 4e-20 Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 1/122 (0%) Query: 1 MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILSEYDINLVIMDINLPGK 60 M IL+ +D+ R L GYDV ++ A + + ++ D +LV+ D+ +P + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLLLARELRE-QANVALMFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLS 119 N L +++ + ++ ++ ++ ++ + I E GA DY+ KPF+ EL L+ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RT 121 Sbjct: 121 EP 122