PredictBias

identification of genomic and pathogenicity islands in prokaryotic genome
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A) Input parameters
GenomeNC_000853.txtThreshold dinucleotide bias2
Threshold codon bias4Threshold %GC bias3
E-value (RPSBlast)0.05Genome (non-pathogenic)
 
B) Compare a potential GI or PAI in related non-pathogenic sp. (phylogenetic tree)
Potential GI or PAI start    end  
Select Organism     
 
C) Potential GIs and PAIs in NC_000853 (download)
S.NoStartEndBiasVirulenceInsertion elementsPrediction
1TM0055TM0070Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
TM0055211-0.102878alpha-glucuronidase
TM00562141.262934oligopeptide ABC transporter, periplasmic
TM00572120.643845oligopeptide ABC transporter, ATP-binding
TM00582120.451860oligopeptide ABC transporter, ATP-binding
TM00592140.798793oligopeptide ABC transporter, permease protein
TM00602130.443292oligopeptide ABC transporter, permease protein
TM00612150.629588endo-1,4-beta-xylanase A
TM0062113-0.860073hypothetical protein
TM0063-215-1.217549hypothetical protein
TM0064-115-0.787402uronate isomerase
TM0065-116-1.582616transcriptional regulator, IclR family
TM0066018-0.8044042-dehydro-3-deoxyphosphogluconate
TM0067116-1.4027342-keto-3-deoxygluconate kinase
TM0068216-1.480329D-mannonate oxidoreductase, putative
TM0069315-1.147299mannonate dehydratase
TM0070213-0.758116endo-1,4-beta-xylanase B
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM0062adhesinb302e-04 Adhesin B signature.
		>adhesinb#Adhesin B signature.

Length = 310

Score = 29.8 bits (67), Expect = 2e-04
Identities = 9/40 (22%), Positives = 15/40 (37%), Gaps = 2/40 (5%)

Query: 1 MKKWFLMSVLGVFAFLIILSGCVSAPGTGGALNKVLKVET 40
MKK + +L + L+ C S + + L V
Sbjct: 1 MKKCRFLVLL--LLAFVGLAACSSQKSSTETGSSKLNVVA 38


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM0065PF08280240.020 M protein trans-acting positive regulator
		>PF08280#M protein trans-acting positive regulator

Length = 530

Score = 24.0 bits (52), Expect = 0.020
Identities = 6/27 (22%), Positives = 12/27 (44%)

Query: 13 FIVKNPGDVSVSEIAEKFNMSVSNAYK 39
I +++ A +S S+AY+
Sbjct: 128 LIKNGSHSRPLTDFARSHFLSNSSAYR 154


2TM0087TM0092Y        NNGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
TM0087-318-3.092511hypothetical protein
TM0088-219-4.069872comE protein, putative
TM0089126-5.198591hypothetical protein
TM0090125-5.713229hypothetical protein
TM0091124-5.013096hypothetical protein
TM0092022-4.113033hypothetical protein
3TM0275TM0281Y        NNGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
TM02752110.600307transcriptional regulator, GntR family
TM02762120.947750L-arabinose isomerase
TM02783130.638148sugar ABC transporter, permease protein
TM02793131.155242sugar ABC transporter, permease protein
TM02802130.609768hypothetical protein
TM0281212-0.012130alpha-L-arabinofuranosidase
4TM0296TM0302Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
TM0296218-2.511896fructokinase
TM0297422-3.049026oxidoreductase, short chain
TM0298427-3.966025alcohol dehydrogenase, zinc-containing
TM0299633-5.248599transcriptional regulator, LacI family
TM0300733-4.696014oligopeptide ABC transporter, periplasmic
TM0301527-3.905007oligopeptide ABC transporter, permease protein
TM0302320-2.128906oligopeptide ABC transporter, permease protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM0297DHBDHDRGNASE332e-05 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase sig...
		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

signature.
Length = 261

Score = 32.7 bits (74), Expect = 2e-05
Identities = 15/31 (48%), Positives = 23/31 (74%)

Query: 13 KVALVTGGGQGIGKAIAQALAAAGAAVLIMD 43
K+A +TG QGIG+A+A+ LA+ GA + +D
Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVD 39


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM0299HTHTETR230.046 TetR bacterial regulatory protein HTH signature.
		>HTHTETR#TetR bacterial regulatory protein HTH signature.

Length = 215

Score = 23.0 bits (49), Expect = 0.046
Identities = 10/41 (24%), Positives = 17/41 (41%)

Query: 4 ATLKDIAEYFGVSISTVSRALSGKPGVSSELREKILEKARE 44
+L +IA+ GV+ + K + SE+ E E
Sbjct: 32 TSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72


5TM0322TM0345Y        Y        YPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
TM0322217-1.435935ABC transporter, periplasmic substrate-binding
TM0324220-2.917296hypothetical protein
TM0325-118-2.901622oxidoreductase, short chain
TM0326-217-2.705747transcriptional regulator, RpiR family
TM0327-215-2.226912phosphoglycerate dehydrogenase, putative
TM0328-115-1.368409*m4C-methyltransferase
TM0329116-0.084501hypothetical protein
TM03302161.647009hypothetical protein
TM03311161.920736orotate phosphoribosyltransferase
TM03320162.154125orotidine 5'-phosphate decarboxylase, putative
TM03330162.043094dihydroorotate dehydrogenase
TM03341151.692332dihydroorotate dehydrogenase electron transfer
TM03351151.348837dihydroorotase
TM03362161.411991hypothetical protein
TM03371171.374962hypothetical protein
TM03383191.071803hypothetical protein
TM03392170.854300hypothetical protein
TM03400151.869611hypothetical protein
TM0341-1151.904156hypothetical protein
TM0342-1142.656689permease, putative
TM0343-1152.9034863-deoxy-7-phosphoheptulonate synthase
TM0344-1142.712130prephenate dehydrogenase
TM0345-1153.0678803-phosphoshikimate 1-carboxyvinyltransferase
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM0325DHBDHDRGNASE377e-07 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase sig...
		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

signature.
Length = 261

Score = 36.6 bits (84), Expect = 7e-07
Identities = 17/38 (44%), Positives = 23/38 (60%)

Query: 4 QGKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEK 41
+GK+ ITGA GIG+ A A +GA +A D + EK
Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEK 44


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM0344ARGDEIMINASE240.014 Bacterial arginine deiminase signature.
		>ARGDEIMINASE#Bacterial arginine deiminase signature.

Length = 409

Score = 24.4 bits (53), Expect = 0.014
Identities = 9/20 (45%), Positives = 13/20 (65%)

Query: 25 VTAFDRDEETMKALEENGIE 44
+ A+ R+ T K EENGI+
Sbjct: 362 IIAYSRNHVTNKLFEENGIK 381


6TM0400TM0434Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
TM0400291.351644sensor histidine kinase
TM04014111.342655thymidine kinase
TM04024120.723990ammonium transporter
TM0403313-0.215916nitrogen regulatory protein P-II
TM0404313-0.028828deoxycytidylate deaminase, putative
TM04053130.408755ferrodoxin oxidoreductase beta subunit
TM0406315-0.522493keto/oxoacid ferredoxin oxidoreductase, gamma
TM04074140.583393diacylglycerol kinase, putative
TM04083131.967706chemotaxis-specific methylesterase
TM04092131.778555hypothetical protein
TM04100132.106227hypothetical protein
TM04110121.719204transcriptional regulator, XylR-related
TM04120121.412817alcohol dehydrogenase, zinc-containing
TM04130130.774260creatinine amidohydrolase, putative
TM0414113-0.396524dehydrogenase
TM0415113-0.605463hypothetical protein
TM0416213-0.938653D-tagatose 3-epimerase-related protein
TM0417214-1.301583hypothetical protein
TM0418313-0.637446sugar ABC transporter, periplasmic
TM0419317-1.113558sugar ABC transporter, permease protein
TM0420216-1.168259sugar ABC transporter, permease protein
TM0421317-1.661591sugar ABC transporter, ATP-binding protein
TM0422216-1.721862hypothetical protein
TM0423217-1.542414glycerol dehydrogenase
TM0424013-1.158652hypothetical protein
TM0425115-1.581500oxidoreductase, putative
TM0426116-1.686033PHT4-related protein
TM0427216-1.590460oxidoreductase, putative
TM0428417-1.628943oxidoreductase, putative
TM0429617-0.741499methyl-accepting chemotaxis protein
TM0430719-1.420218sugar ABC transporter, permease protein
TM0431519-0.664515sugar ABC transporter, permease protein
TM0432418-0.563872sugar ABC transporter, periplasmic
TM0433417-0.377926pectate lyase
TM0434316-0.765260alpha-glucosidase, putative
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM0408HTHFIS230.039 FIS bacterial regulatory protein HTH signature.
		>HTHFIS#FIS bacterial regulatory protein HTH signature.

Length = 484

Score = 23.3 bits (50), Expect = 0.039
Identities = 10/40 (25%), Positives = 17/40 (42%), Gaps = 1/40 (2%)

Query: 6 IRVLVVDDSAFMRMVLKDIIDSQP-DMKVVGFAKDGLEAV 44
+LV DD A +R VL + D+++ A +
Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWI 43


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM0411HTHFIS240.033 FIS bacterial regulatory protein HTH signature.
		>HTHFIS#FIS bacterial regulatory protein HTH signature.

Length = 484

Score = 23.6 bits (51), Expect = 0.033
Identities = 8/41 (19%), Positives = 21/41 (51%)

Query: 2 LNEMEKTVLQMIMAGSDISRVDISRALGISKPVVSKAVNRL 42
L EME ++ + + +++ + LG+++ + K + L
Sbjct: 433 LAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL 473


7TM0536TM0555Y        NNGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
TM05362120.084563hypothetical protein
TM05371131.110564hypothetical protein
TM0538-2132.265398cation efflux system protein
TM0539-1152.641425tryptophan synthase subunit beta
TM0540-1141.718534fumarate hydratase, N-terminal subunit
TM0541-1132.689021fumarate hydratase, C-terminal subunit
TM05420132.610867malate oxidoreductase
TM05430142.919773hypothetical protein
TM05440163.376599ABC transporter, ATP-binding protein
TM05450163.331159homoserine kinase, putative
TM05461194.253613threonine synthase
TM05470193.961287aspartokinase II
TM05480224.422585acetolactate synthase, large subunit
TM05490224.522245acetolactate synthase, small subunit
TM05500224.556990ketol-acid reductoisomerase
TM05510214.654945dihydroxy-acid dehydratase
TM0552-1234.5513632-isopropylmalate synthase
TM0553-1204.3944832-isopropylmalate synthase
TM05540173.8387303-isopropylmalate dehydratase, large subunit
TM0555-1153.5264733-isopropylmalate dehydratase, small subunit
8TM0580TM0603Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
TM0580-1234.136542cell division protein FtsH
TM05810193.464036hypothetical protein
TM05820182.847943hypothetical protein
TM0583-1213.913569lipopolysaccharide biosynthesis protein
TM0584-1183.216902hypothetical protein
TM0585-2173.385959lipopolysaccharide biosynthesis protein BplA
TM0586-2163.026362hypothetical protein
TM0587-2183.671266putative manganese-dependent inorganic
TM05880214.766424rod shape-determining protein MreB
TM05891215.046349hypothetical protein
TM05902255.432624penicillin-binding protein 2
TM05912295.366250amino acid ABC transporter, ATP-binding
TM05923295.659120amino acid ABC transporter, permease protein
TM05932315.604331amino acid ABC transporter, periplasmic amino
TM05941295.253832hypothetical protein
TM05953314.822501sugar ABC transporter, periplasmic
TM05963304.439163sugar ABC transporter, permease protein
TM05973284.344967hypothetical protein
TM05984294.115836sugar ABC transporter, permease protein
TM05994263.402612hypothetical protein
TM06002282.484777hypothetical protein
TM06013240.709822hypothetical protein
TM06022211.232723iron-dependent transcriptional repressor,
TM06033222.743673ribosomal protein S6
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM0588SHAPEPROTEIN612e-15 Bacterial cell shape determinant MreB/Mbl protein s...
		>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein

signature.
Length = 347

Score = 60.9 bits (148), Expect = 2e-15
Identities = 23/43 (53%), Positives = 31/43 (72%)

Query: 1 MLRKDIGIDLGTANTLVFLRGKGIVVNEPSVIAIDSTTGEILK 43
M D+ IDLGTANTL++++G+GIV+NEPSV+AI K
Sbjct: 8 MFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPK 50


9TM0613TM0667Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
TM0613020-5.098512hypothetical protein
TM0614-120-5.780328hypothetical protein
TM0615021-5.639863hypothetical protein
TM0616125-5.806219hypothetical protein
TM0617229-5.974336hypothetical protein
TM0618329-6.052493hypothetical protein
TM0619431-6.942379hypothetical protein
TM0620635-8.072814lipopolysaccharide biosynthesis protein
TM0622841-9.809135lipopolysaccharide biosynthesis protein,
TM06231047-11.927188hypothetical protein
TM06241150-13.262614N-acetylglucosaminyl-phosphatidylinositol
TM06251149-12.648937hypothetical protein
TM06261046-11.528192hypothetical protein
TM0627737-9.722133lipopolysaccharide biosynthesis protein
TM0628632-8.615965hypothetical protein
TM0629427-7.276709hypothetical protein
TM0630117-4.086453nucleotide sugar epimerase, putative
TM0631017-4.444960lipopolysaccharide biosynthesis protein
TM0632-119-1.117415extracellular polysaccharide
TM06333253.643071flagellar-related protein
TM06343254.185108hypothetical protein
TM06354263.925656hypothetical protein
TM06363253.435303hypothetical protein
TM06373253.278496hypothetical protein
TM06381232.634135polysaccharide export protein, putative
TM06391190.672551hypothetical protein
TM0640219-0.032949hypothetical protein
TM0641218-0.199063hypothetical protein
TM06422200.235060hypothetical protein
TM06433180.235782clostripain-related protein
TM0644318-0.168836hypothetical protein
TM06452190.807015NH(3)-dependent NAD(+) synthetase, putative
TM06461200.503938hypothetical protein
TM06472221.843667hypothetical protein
TM06482222.438594hypothetical protein
TM06491242.841532hypothetical protein
TM06501263.756741hypothetical protein
TM06512273.286462hypothetical protein
TM06522274.172408hypothetical protein
TM06530284.126124hypothetical protein
TM06540263.746973spermidine synthase
TM06553264.056884hypothetical protein
TM06565283.398163hypothetical protein
TM06575303.953201rubrerythrin
TM06584243.742487neelaredoxin
TM06594223.741320rubredoxin
TM06603214.175266hypothetical protein
TM06611203.947212hypothetical protein
TM06620184.036286acyl carrier protein
TM06630194.297078hypothetical protein
TM06640184.554710hypothetical protein
TM06650173.895349cysteine synthase
TM06660162.481212serine acetyltransferase
TM0667213-0.049747hypothetical protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM0630NUCEPIMERASE412e-08 Nucleotide sugar epimerase signature.
		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

Length = 334

Score = 40.9 bits (96), Expect = 2e-08
Identities = 14/30 (46%), Positives = 21/30 (70%)

Query: 15 RVLVTGGAGAVGSNLVRRLLDLGAFVIVID 44
+ LVTG AG +G ++ +RLL+ G V+ ID
Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGID 31


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM0633FLGFLGJ412e-08 Flagellar protein FlgJ signature.
		>FLGFLGJ#Flagellar protein FlgJ signature.

Length = 313

Score = 40.9 bits (95), Expect = 2e-08
Identities = 15/40 (37%), Positives = 25/40 (62%)

Query: 5 FLERFSESAFLLERLTGIDGKILLAQSALETGWGRHTVGN 44
FL + S A L + +G+ ++LAQ+ALE+GWG+ +
Sbjct: 152 FLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRR 191


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM0643SSPAKPROTEIN260.004 Invasion protein B family signature.
		>SSPAKPROTEIN#Invasion protein B family signature.

Length = 133

Score = 26.1 bits (57), Expect = 0.004
Identities = 10/28 (35%), Positives = 13/28 (46%)

Query: 7 IVVSALFLSGCMPEIYTHASTPSTIIAD 34
+V +LF GC P I T + S I
Sbjct: 9 LVRDSLFTIGCPPSIITDLDSHSAITIS 36


10TM0705TM0710Y        NNGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
TM0705213-0.590761ABC transporter, ATP-binding protein
TM0706211-0.748408hypothetical protein
TM07073140.443256glucose-inhibited division protein B
TM07084140.684201hypothetical protein
TM07095160.156965hypothetical protein
TM07102130.233946transcriptional regulator, MarR family
11TM0776TM0800Y        NYGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
TM07763150.748087transposase, putative
TM07770140.141007transposase
TM07780140.491325hypothetical protein
TM0779-2160.353548hypothetical protein
TM0780-2171.641900bacterioferritin comigratory protein, ahpC/TSA
TM0781-1161.977024hypothetical protein
TM0782-1162.753672hypothetical protein
TM0783-1194.402024hypothetical protein
TM0784-2163.485248hypothetical protein
TM0785-1183.550098bacteriocin
TM0786-1173.325532hypothetical protein
TM0787-1173.243265putative thiazole biosynthetic enzyme
TM07880172.754930thiamine biosynthesis protein ThiC
TM07890131.330060hypothetical protein
TM07900141.810895hypothetical protein
TM0791-1132.137498hypothetical protein
TM0792-1132.081444hypothetical protein
TM0793-1131.766361ABC transporter, ATP-binding protein
TM0794-1112.017083hypothetical protein
TM07950123.762980sugar kinase, pfkB family
TM0796-1133.945300hypothetical protein
TM0797-1134.2930112-phosphosulfolactate phosphatas
TM0798-1144.120502malonyl CoA-acyl carrier protein transacylase
TM0799-1164.156191bioY protein
TM0800-1143.461796hypothetical protein
12TM0946TM0956Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
TM0946217-2.200067hypothetical protein
TM0947321-3.021824hypothetical protein
TM0948423-3.124148hypothetical protein
TM0949424-3.239709transcriptional regulator, LacI family
TM0950525-2.709166hypothetical protein
TM0951529-3.567936hypothetical protein
TM0952530-4.055524glycerol kinase
TM0953630-4.061465transketolase, C-terminal subunit
TM0954631-4.930891transketolase, N-terminal subunit
TM0955531-5.115727ribose ABC transporter, permease protein
TM0956328-4.764269ribose ABC transporter, ATP-binding protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM0949HTHTETR260.004 TetR bacterial regulatory protein HTH signature.
		>HTHTETR#TetR bacterial regulatory protein HTH signature.

Length = 215

Score = 25.7 bits (56), Expect = 0.004
Identities = 10/38 (26%), Positives = 20/38 (52%)

Query: 6 TINDVAKLAGVSISTVSRYLKDPSQVSEKLGERIREAI 43
++ ++AK AGV+ + + KD S + ++ E I
Sbjct: 33 SLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70


13TM0967TM0972Y        NYGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
TM0967018-3.038838integrase-recombinase protein
TM0968120-3.774040hypothetical protein
TM0969325-3.913346hypothetical protein
TM0970224-3.736000hypothetical protein
TM0971226-3.883131hypothetical protein
TM0972224-3.701044conserved hypothetical protein, GGDEF domain
14TM0988TM0998Y        NNGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
TM0988-120-3.858011hypothetical protein
TM0989127-4.664172hypothetical protein
TM0990128-4.829747hypothetical protein
TM0991333-4.455639hypothetical protein
TM0992428-5.299073hypothetical protein
TM0993424-1.357613hypothetical protein
TM0994424-1.696932hypothetical protein
TM0995326-3.027632hypothetical protein
TM0996226-3.857325hypothetical protein
TM0997122-3.524243hypothetical protein
TM0998125-3.331129heavy metal resistance transcriptional
15TM1061TM1072Y        NNGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
TM1061321-0.588786hypothetical protein
TM1062522-1.852839beta-glucuronidase
TM1063828-1.470483oligopeptide ABC transporter, ATP-binding
TM1064825-2.219763oligopeptide ABC transporter, ATP-binding
TM1065826-3.166509oligopeptide ABC transporter, permease protein
TM1066521-2.512069oligopeptide ABC transporter, permease protein
TM1067115-1.031779oligopeptide ABC transporter, periplasmic
TM1068-1171.789094alpha-glucosidase, putative
TM1069-1141.508903transcriptional regulator, DeoR family
TM10700172.570034hypothetical protein
TM10711183.025988sugar isomerase
TM10721213.144652rhamnulose-1-phosphate aldolase
16TM1109TM1124Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
TM11092152.374267hypothetical protein
TM11105142.351709hypothetical protein
TM11113142.360386hypothetical protein
TM11122151.639869hypothetical protein
TM11132130.991293hypothetical protein
TM11141130.281407hypothetical protein
TM1115-112-0.202184hypothetical protein
TM1116-111-0.887654hypothetical protein
TM1117116-2.151200general secretion pathway protein D, putative
TM1118114-1.842942hypothetical protein
TM1119114-1.756161hypothetical protein
TM1120216-2.077275glycerol-3-phosphate ABC transporter,
TM1121117-3.439478glycerol-3-phosphate ABC transporter, permease
TM1122115-3.391454glycerol-3-phosphate ABC transporter, permease
TM1123013-2.997821flagellar hook-associated protein 2, putative
TM1124-214-4.071366hypothetical protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM1124OMADHESIN270.002 Yersinia outer membrane adhesin signature.
		>OMADHESIN#Yersinia outer membrane adhesin signature.

Length = 455

Score = 26.8 bits (58), Expect = 0.002
Identities = 11/33 (33%), Positives = 21/33 (63%)

Query: 10 GNEVLRREITRRELHVKENESTPVAEMKKQQEE 42
G+E L R++T K+ ++ VA++KK+ E+
Sbjct: 188 GHESLNRQLTHLAAGTKDTDAVNVAQLKKEIEK 220


17TM1175TM1223Y        Y        YPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
TM11752170.700430ferredoxin
TM11763150.700699transcriptional regulator, metal-sensing
TM11777130.241600hypothetical protein
TM11785150.377298acetyltransferase-related protein
TM1179411-0.406136flagellar protein FliS
TM1180411-0.381895hypothetical protein
TM1181311-0.368392hypothetical protein
TM1182211-0.733669chromosome segregation SMC protein, putative
TM1183-210-1.357613oxidoreductase, aldo/keto reductase family
TM1184-120-5.591279pleD-related protein
TM1185020-5.248390methylglyoxal synthase
TM1186019-4.624559hypothetical protein
TM1187-113-3.166797hypothetical protein
TM1188-111-1.780761hypothetical protein
TM1189-111-1.430849*hypothetical protein
TM1190-1132.128243galactokinase
TM1191-2121.484742galactose-1-phosphate uridylyltransferase
TM1192-1110.821995alpha-galactosidase
TM1193112-0.110086beta-galactosidase
TM1194513-0.105466oligopeptide ABC transporter, ATP-binding
TM1195311-0.478697beta-galactosidase
TM1196413-1.057236oligopeptide ABC transporter, ATP-binding
TM1197212-1.194447oligopeptide ABC transporter, permease protein
TM1198111-0.809904oligopeptide ABC transporter, permease protein
TM1199011-0.166239oligopeptide ABC transporter, periplasmic
TM1200-111-0.894106transcriptional regulator, LacI family
TM1201-112-0.709809arabinogalactan endo-1,4-beta-galactosidase,
TM1202-114-0.852159maltose ABC transporter, permease protein
TM12030160.678498maltose ABC transporter, permease protein
TM12040171.589594maltose ABC transporter, periplasmic
TM12053171.106253hypothetical protein
TM12062171.587711hypothetical protein
TM12071131.343494hypothetical protein
TM12080121.701787hypothetical protein
TM12091121.928786hypothetical protein
TM12101131.904031hypothetical protein
TM12111132.236566NADH dehydrogenase, putative
TM12122152.372715NADH dehydrogenase subunit N
TM12132152.575175NADH dehydrogenase, putative
TM12141141.883080NADH dehydrogenase beta subunit
TM12151131.425648NADH dehydrogenase, 30 kDa subunit, putative
TM12162121.654145NADH dehydrogenase delta subunit
TM12171111.022166glutamate synthase, beta subunit
TM12180141.142982transcriptional regulator, LacI family
TM12190120.882766oligopeptide ABC transporter, ATP-binding
TM12202111.390202oligopeptide ABC transporter, ATP-binding
TM1221411-0.067896oligopeptide ABC transporter, permease protein
TM1222290.206409oligopeptide ABC transporter, permease protein
TM12232110.667197oligopeptide ABC transporter, periplasmic
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM1199CHLAMIDIAOMP270.003 Chlamydia major outer membrane protein signature.
		>CHLAMIDIAOMP#Chlamydia major outer membrane protein signature.

Length = 393

Score = 26.5 bits (58), Expect = 0.003
Identities = 14/35 (40%), Positives = 19/35 (54%)

Query: 1 MKKVLVFVFLALIAVSAVMAQMLPPGIPREKTLIL 35
MKK+L V + SA Q LP G P E +L++
Sbjct: 1 MKKLLKSVLVFAALSSASSLQALPVGNPAEPSLMI 35


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM1200HTHTETR295e-04 TetR bacterial regulatory protein HTH signature.
		>HTHTETR#TetR bacterial regulatory protein HTH signature.

Length = 215

Score = 28.8 bits (64), Expect = 5e-04
Identities = 8/30 (26%), Positives = 16/30 (53%)

Query: 6 VTIRDIAEKAGVSINTVSRALNNKPDISEE 35
++ +IA+ AGV+ + +K D+ E
Sbjct: 32 TSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM1211PF06580230.047 Sensor histidine kinase
		>PF06580#Sensor histidine kinase

Length = 349

Score = 22.9 bits (49), Expect = 0.047
Identities = 8/44 (18%), Positives = 16/44 (36%)

Query: 1 MISLLVAVPLLAAFVSLFWKKASDVLFSLVALFNVIVVLSKWFP 44
++ L++ + W K + L L +V+ WF
Sbjct: 50 LMGLVLTHAYRSFIKRQGWLKLNMGQIILRVLPACVVIGMVWFV 93


18TM1296TM1339Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
TM1296227-5.679597ribonuclease H-related protein
TM1297128-5.421727oxidoreductase, putative
TM1298229-6.500447hypothetical protein
TM1299427-6.000344hypothetical protein
TM1300427-5.686499hypothetical protein
TM1301426-5.507129astB/chuR-related protein
TM1302321-2.713466ABC transporter, ATP-binding protein
TM1303724-3.191627hypothetical protein
TM13041032-3.058294hypothetical protein
TM1305628-2.848083hypothetical protein
TM1306527-2.629444hypothetical protein
TM1307528-2.839316hypothetical protein
TM1308428-2.878213hypothetical protein
TM1309227-4.270200hypothetical protein
TM1310126-4.558294ABC transporter, ATP-binding protein
TM1311331-5.968595hypothetical protein
TM1312641-9.521316hypothetical protein
TM1313230-7.377570hypothetical protein
TM1314330-7.329127hypothetical protein
TM1315327-6.908303hypothetical protein
TM1316327-6.861219hypothetical protein
TM1317223-6.012097astB/chuR-related protein
TM1319017-3.842424ABC transporter, ATP-binding protein
TM1321117-3.678240hypothetical protein
TM1322115-3.310644hypothetical protein
TM1323114-2.795648hypothetical protein
TM1324015-3.087195astB/chuR-related protein
TM1325117-3.430787astB/chuR-related protein
TM1326121-4.068747hypothetical protein
TM1327222-5.004067ABC transporter, ATP-binding protein
TM1328226-5.673198ABC transporter, ATP-binding protein
TM1329636-8.707602hypothetical protein
TM1330423-6.452554lacI family transcriptional regulator,
TM1331320-5.396433hypothetical protein
TM1332421-4.697992hypothetical protein
TM1333521-4.750036hypothetical protein
TM1334420-4.415126hypothetical protein
TM1335316-0.729781hypothetical protein
TM13366200.752318permease, putative
TM13379231.222620hypothetical protein
TM13384212.152062hypothetical protein
TM13392152.309090hypothetical protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM1336LIPPROTEIN48260.005 Mycoplasma P48 major surface lipoprotein signature.
		>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature.

Length = 428

Score = 25.7 bits (56), Expect = 0.005
Identities = 8/30 (26%), Positives = 12/30 (40%)

Query: 12 SFVSLIGTRIYQVALAWWLYSKTGSSEYVG 41
S + I +Y+ L L + G YV
Sbjct: 310 SVLKHIKQAVYETLLDLILEKEEGYKPYVV 339


19TM1402TM1410Y        NNGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
TM1402-316-3.803258hypothetical protein
TM1403-218-4.331806antibiotic ABC transporter, ATP-binding
TM1404-222-4.969962antibiotic ABC transporter, transmembrane
TM1405-224-5.546198lipopolysaccharide biosynthesis protein-related
TM1406-224-5.463533hypothetical protein
TM1407-125-5.443155hypothetical protein
TM1408127-5.590170hypothetical protein
TM1409-122-4.429321hypothetical protein
TM1410-117-3.007789hypothetical protein
20TM1630TM1645Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
TM1630215-0.658585hypothetical protein
TM1631611-1.016950hypothetical protein
TM1632713-0.833871hypothetical protein
TM1633712-0.533984ATP-dependent protease LA
TM1634810-0.780139hypothetical protein
TM16356110.962211exonuclease, putative
TM16366110.864795hypothetical protein
TM16370141.877467hypothetical protein
TM16380121.602768ABC transporter, ATP-binding protein
TM1639-1131.518771electron transfer protein, putative
TM1640-1121.114670glutamate synthase, beta subunit
TM1641011-0.575769dihydrofolate reductase
TM1642010-0.657905aspartate carbamoyltransferase, catalytic and
TM1643112-0.648481hypothetical protein
TM1644212-0.484250quinolinate synthetase
TM1645213-0.968230nicotinate-nucleotide pyrophosphorylase
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM1642SECA230.034 SecA protein signature.
		>SECA#SecA protein signature.

Length = 901

Score = 23.3 bits (50), Expect = 0.034
Identities = 12/32 (37%), Positives = 16/32 (50%), Gaps = 3/32 (9%)

Query: 13 IEDLSVEEQMFLYEKTRELKQRWYSGEDVSDF 44
+E LS EE L KT E + R GE + +
Sbjct: 35 MEKLSDEE---LKGKTAEFRARLEKGEVLENL 63


21TM1661TM1666Y        NNGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
TM16610173.040707polypeptide deformylase
TM1662-2193.608373stationary phase survival protein
TM1663-2193.287860ABC transporter, ATP-binding protein
TM1664-2183.064013hypothetical protein
TM1665-2193.286431hypothetical protein
TM1666-3193.006638succinyl-diaminopimelate desuccinylase
22TM1742TM1750Y        NNGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
TM1742218-0.606556nagD protein, putative
TM1743522-1.434443oxidoreductase, aldo/keto reductase family
TM1744728-2.850735L-allo-threonine aldolase
TM1745836-4.978431hypothetical protein
TM1746940-6.041531oligopeptide ABC transporter, periplasmic
TM17471042-7.284423oligopeptide ABC transporter, permease protein
TM1748939-7.069326oligopeptide ABC transporter, permease protein
TM1749532-5.728748oligopeptide ABC transporter, ATP-binding
TM1750225-3.687923oligopeptide ABC transporter, ATP-binding
23TM1786TM1811Y        NYGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
TM1786425-3.774805hypothetical protein
TM1787327-3.948722hypothetical protein
TM1788225-4.626632*conserved hypothetical protein, GGDEF domain
TM1789-121-4.113936hypothetical protein
TM1790023-4.724960hypothetical protein
TM1791122-4.664683hypothetical protein
TM1792021-4.765042hypothetical protein
TM1793120-4.640005hypothetical protein
TM1794117-4.236297hypothetical protein
TM1795118-4.211291hypothetical protein
TM1796012-2.911774hypothetical protein
TM1797112-3.273300hypothetical protein
TM1798112-2.621556hypothetical protein
TM1799113-2.670772hypothetical protein
TM1800116-3.068614hypothetical protein
TM1801016-2.639006hypothetical protein
TM1802117-3.397615hypothetical protein
TM1803017-1.923642dnaJ-related protein
TM1804015-1.810718hypothetical protein
TM1805114-1.910895hypothetical protein
TM1806211-1.857214hypothetical protein
TM1807212-3.530204hypothetical protein
TM1808213-3.954940hypothetical protein
TM1809214-4.786171hypothetical protein
TM1810115-5.105012hypothetical protein
TM1811016-4.696902hypothetical protein
24TM1539TM1544N        Y        NPathogenicity Island (unbiased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
TM15390172.330928flagellar P-ring protein precursor
TM1540-1151.046744flagellar L-ring protein
TM1541-211-0.163443flagellar protein FlgA, putative
TM1542-110-0.005521flagellar basal-body rod protein FlgG
TM1543-29-0.401255flagellar basal-body rod protein FlgF
TM1544-18-0.632053rod shape-determining protein MreB
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM1539FLGPRINGFLGI322e-05 Flagellar P-ring protein signature.
		>FLGPRINGFLGI#Flagellar P-ring protein signature.

Length = 373

Score = 32.2 bits (73), Expect = 2e-05
Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 7 LAVLLVIVLTITFSFSVTTRIKDIAFFRGARDNQLFGI 44
L + L+ + + T+RIKDIA + RDNQL G
Sbjct: 11 LVFSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGY 48


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM1542FLGHOOKAP1376e-07 Flagellar hook-associated protein signature.
		>FLGHOOKAP1#Flagellar hook-associated protein signature.

Length = 546

Score = 36.9 bits (85), Expect = 6e-07
Identities = 10/35 (28%), Positives = 22/35 (62%)

Query: 4 SLYSAATGMSAQQFKLDTIANNLANVDTTGYKKVR 38
+ +A +G++A Q L+T +NN+++ + GY +
Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQT 37


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM1543FLGHOOKAP1293e-04 Flagellar hook-associated protein signature.
		>FLGHOOKAP1#Flagellar hook-associated protein signature.

Length = 546

Score = 29.2 bits (65), Expect = 3e-04
Identities = 10/35 (28%), Positives = 19/35 (54%)

Query: 4 GIYNAAMGMLVDMAKLDRIANDLANVDTAGYKQDR 38
I NA G+ A L+ +N++++ + AGY +
Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQT 37


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
TM1544SHAPEPROTEIN538e-13 Bacterial cell shape determinant MreB/Mbl protein s...
		>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein

signature.
Length = 347

Score = 53.2 bits (128), Expect = 8e-13
Identities = 21/39 (53%), Positives = 29/39 (74%)

Query: 1 MPRGDIGIDLGTASIIVYKRGEGIVLHEPSVVAISEKTG 39
M D+ IDLGTA+ ++Y +G+GIVL+EPSVVAI +
Sbjct: 8 MFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRA 46



 
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