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This individual will use proprietary de novo methods to design leads for protein targets and develop methods to optimize their physiochemical properties.
Responsibilities:
· Demonstrated experience in applying typical modeling techniques to problems in the pharmaceutical industry, ranging from lead identification to optimization of compounds as preclinical candidates, is essential.
· Experience with de novo and ligand design methods, 2D and 3D QSAR/QSPR, development of physio-chemical/ADME models of biological activity, and strong communication skills are essential.
· Experience with compound library design/diversity analysis, combinatorial library design and informatics, homology model building, software design, experience in C++, object-oriented programming, C, Fortran programming, or database management is desirable.
Qualifications:
· Ph.D in computational chemistry, organic chemistry, physical chemistry, biochemistry, biophysics, or the equivalent.
Salary/Benefits:
Salary: $110,000
Benefits: Employee stock option plan, comprehensive health, dental and vision coverage, tuition reimbursement, life insurance and a 401K plan.
Contact:
ileibson[at]execrecruiter.com
Discussion forums: Computational Chemist needed for the Northeast
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