Not logged in

Bioinformatics.org

Membership (44435+)

Basic Free!
Professional

Group hosting

Hosted groups (569)

Wiki
Franklin Award
Sponsorships

Careers

About bioinformatics
Bioinformatics jobs

Research

All information groups
Online databases

Online analysis tools

Online education tools

Atlas of Macromolecules

More tools

Development

All software groups
FTP repository
SVN & CVS repositories
Mailing lists

Forums

News & Commentary

Submit

BACKGROUND

The Wellcome Trust Sanger Institute operates at the forefront of genomics, sequencing and analyses targeting a wide range of genomes from single cell pathogens to higher vertebrates, with an emphasis on genomes relevant to human medicine and welfare. The Cancer Genome Project at the Institute has led the way in the systematic analysis of cancer genomes by using the human genome sequence and high throughput mutation detection techniques to identify somatically acquired sequence variants/mutations and hence identify genes critical in the development of human cancers (http://www.sanger.ac.uk/research/projects/cancergenome/).

RESPONSIBILITIES

A highly motivated Bioinformatician is required, to undertake the analysis of genomic data from defined projects carried out by teams 82 (Mouse genomics) and 163 (Haematological cancer genetics).

This is a new position that has been created to carry out the analysis of genomic datasets generated by our teams. We perform genetic screens using insertional mutagens, including cancer gene/pathway discovery and drug sensitivity/resistance screens in vivo. Additionally, we are generating parallel genomic datasets from bespoke genetically modified stem cells and mice, including DNA methylation, gene expression and chromatin immunoprecipitation. The analysis, integration and visualisation of these datasets will be an important role of the successful applicant, who will be able to harness specific expertise already available at the Sanger Institute for such analyses.

The post holder will have good knowledge of molecular biology, bioinformatics and data acquisition methods. They will have a track record of delivering complex projects and a solid publication record. Highly experienced in system design, programming and the use of relational databases, they will ensure large scale data are managed and analysed in a robust, efficient manner.

Additional, they will be responsive and reactive to the needs of their project, hands-on and able to instruct others in the use of simple command line skills for routine tasks. It is envisaged that they will be able, in due course, to take on strategic responsibilities, while maintaining a hands-on attitude.

REQUIREMENTS

Essential Skills:

PhD or equivalent expertise in a relevant subject area (e.g. Computational Biology, Genetics/Genomics, Computer Science, Physics or similar)
Excellent programming skills (e.g. C, C++, Perl, Python, Java)
Strong knowledge and experience of UNIX/Linux and cluster computing
Strong statistical and quantitative skills
Ability to perform & troubleshoot bioinformatic analyses competently and independently
Strong publication record
Ability to work to tight deadlines
Ability to communicate ideas and results effectively
Ability to work within a team
Ability to work independently and organise own workload

PREFERENCES

Ideal Skills:

Experience of developing software systems
Education or experience in biomedical research
Experience with analysis of next generation sequencing data
Experience with analysis of -omics data sets
Experience in presenting data to outside groups or at national/international meetings
Previous experience with stem cells
Previous work with mouse-derived data & databases

TERMS

This position is fixed-term for 3 years with a 6-month probation period.

COMPENSATION

Salary range: GBP 29,750 to GBP 37,525pa dependent on experience.

The Institute has excellent purpose built facilities on the Genome Campus, Hinxton on the outskirts of Cambridge. We offer a comprehensive range of benefits including a final salary pension scheme and excellent on-site facilities. Further details can be found on our website https://jobs.sanger.ac.uk.

HOW TO APPLY

To submit your CV and apply for this job please go to https://jobs.sanger.ac.uk to register and apply on line.

DEADLINE

Closing date: 12th March 2013

Discussion forums: Opportunity: Senior BIOINFORMATICIAN (#81363) @ Wellcome Trust Sanger Institute -- Hinxton/Cambridge, UK

Expanded view | Monitor forum | Save place

Start a new thread:

You have to be logged in to post a reply.