[Next-Generation Sequencing Book]
  • [Photo] Abhishek Pratap • February 11, 2014
    Starting February 10, 2014
    https://www.synapse.org/#!Synapse:syn1734172

    The Rheumatoid Arthritis Responder DREAM Challenge tasks participants to predict the response of Rheumatoid Arthritis patients to anti-TNF therapy based on genetics and clinical data.

    The Data. Challenge participants can now download the 2.5 million SNPS and clinical information of about 2000 patients. Data can be downloaded from the Challenge website (https://www.synapse.org/#!Synapse:syn1734172/files/).

    Data Download Requirements. To download the data please follow the directions on the Challenge website to register for the Challenge and complete the mandatory data use agreement.

    Leaderboard/Compute Resources. We will implement a Leaderboard for the preliminary assessment of predictive models. We will also shortly provide access to an IBM ZEC12 system with 20 processors, 124 GB memory and with 9 TB storage space in order to support the computational need of the Challenge participants.

    Publication Opportunities. We are working closely with Nature Genetics to implement a novel process of Challenge Assisted Peer Review as anticipated in Nat Genet. 2013 May;45(5):468-9. Our aim is to increase transparency of peer review and help in the identification of methods deserving of publication.

    Presentation at the DREAM Conference. The best performing teams will be invited to attend and give an oral presentation at the 2014 RECOMB/ISCB Regulatory, Systems Genomics and DREAM conference

    Discussion Forum. A community forum is available where you can post your questions about the Challenge and interact with other Challenge participants as well as Challenge organizers. We will be posting information to the forum throughout the Challenge. To sign up for the forum, please follow this link:(http://support.sagebase.org/sagebase/topics/welcome_to_the_rheumatoid_arthritis_responder_challenge?rfm=1).

    Challenge Webinar. On February 26th at 9am Pacific, we will be holding a live webinar to describe the scientific rationale behind the Challenge, a tutorial for data access, information on timelines, incentives, and leaderboards. To register for the webinar, please follow this link: https://attendee.gotowebinar.com/register/2853746502066685953

Discussion forums: Events: The Rheumatoid Arthritis Responder DREAM Challenge is Now Open for Participation

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