BACKGROUND

A shared postdoc position is available between Symphogen A/S and the laboratory of Prof Dr Rune Linding, a world-leading network biologist whose research focuses on the mechanisms by which cells use signaling networks to respond and adapt to changes in their environment. We are seeking a highly motivated and brilliant postdoc to join our highly dynamic, productive and stimulating lab.

The group and our research:
The Linding Laboratory is a network biology research group based at the Biotech Research and Innovation Centre at the University of Copenhagen (BRIC). Our lab explores biological systems by both generating high-throughput data and developing algorithms aimed at predicting cell behavior with accuracy similar to those of weather or aircraft models. A major focus of our lab is studying cellular signal processing and decision-making during cancer progression.

RESPONSIBILITIES

In this position, the successful applicant will perform large-scale integrative studies, combining next generation sequencing, global phospho-proteomics and high content screening, with computational models in order to identify the signaling networks involved in cell migration. Following target identification the applicant will generate novel antibody based anti-cancer therapies that can be taken further into pre-clinical and clinical testing.

The identified targets and therapies will be utilized in a network medicine project focused on developing novel treatments for cancer and will be related to our recent studies on phosphorylation networks and network medicine (Creixell et al. 2012 Nature Biotechnology, Erler & Linding Cell 2012, Bakal, Linding et al. Science 2008, Tan et al. Science 2009 and Tan et al. Science 2011 and Jørgensen et al. Science 2009). The project is a collaboration between the Linding Laboratory, Prof. Doug Lauffenburger's lab at MIT, Prof. Norbert Perrimon's lab at Harvard, Assoc. Prof. Janine Erler's lab at BRIC, Symphogen A/S, Silicon Graphics Inc. and PerkinElmer GmbH.

REQUIREMENTS

Candidates should hold a PhD degree or equivalent in systems biology, molecular biology or other relevant field. Experience in large-scale systems studies, mammalian tissue culture, cell imaging and/or antibody development is desired. Experience in mass-spectrometry and (phospho) proteomics techniques is a distinct advantage.

The post-holder must be keen to generate, analyze and computationally handle large-scale quantitative data to reach a deeper understanding of the biological question at hand. Applicants should be able to work independently and to plan and carry out complicated tasks, while also being part of a large and dynamic group. Strong communication skills in English, both written and spoken are required.

TERMS

Salary, pension and terms of employment will be in accordance with the agreement between the Ministry of Finance and The Academics Central organization.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the "Memorandum on Job Structure for Academic Staff at the Universities" of June 28, 2013.

COMPENSATION

Currently, the monthly salary starts at 31.951 DKK/ca. 4.250 Euro plus pension. Depending on qualifications, a higher salary may be negotiated.

HOW TO APPLY

On-line via our advertisement on http://employment.ku.dk/faculty/.
Here you also find the full legal advertisement.

DEADLINE

5th October 2014