[Next-Generation Sequencing Book]
  • [Photo] Mary Grant • December 13, 2014

    BACKGROUND

    The Basic Science Program (BSP) pursues independent, multidisciplinary research programs in basic or applied molecular biology, immunology, retrovirology, cancer biology or human genetics. Research efforts and support are an integral part of the Center for Cancer Research (CCR) at the Frederick National Laboratory for Cancer Research (FNLCR).

    RESPONSIBILITIES

    The Microbiome Core undertakes the characterization of microbiome samples by next generation sequencing to determine composition and variation as influenced by immune, genetic, and host health factors. The core provides support across a spectrum of processes, from nucleic acid isolation through bioinformatics and statistical analysis. The Bioinformatics Analyst III will be responsible for computational handling and analysis of Next Generation sequences in multiple output file formats for multiple purposes as part of a team to characterize microbiome samples. This work will be done at the Bethesda, Maryland campus.

    REQUIREMENTS

    • Possession of a Bachelor's degree in biomedical science/bioinformatics/math/computer related field from an accredited college or university or four (4) years related experience in lieu of degree
    • Foreign degrees must be evaluated for U.S. equivalency
    • In addition to educational requirements, a minimum of six (6) years related experience in a laboratory environment with a strong background in database management and utility programming
    • Familiarity with sequence data formats and processing from Next Generation platforms (Illumina, 454, etc.)
    • Ability to use common bioinformatic programs and databases in the area of automated bioinformatics workflows (e.g. GALAXY)
    • Ability to use, maintain, or modify microbiome analysis pipelines (e.g. Qiime, Mothur), and databases (Greengenes)
    • Ability to set-up and manage databases for storage of sequence and biosample information (SQL, MYSQL, or other database languages)
    • Demonstrated skill in programming/scripting languages (C, C++, Perl, Python, Shell)
    • Familiarity with bioinformatics tools for sequence identification, evaluation and assembly (BLAST, BOWTIE, BWA, etc.)
    • Experience in statistical data analysis, evaluation and visualization, including familiarity with statistical software (e.g., R, S, SPSS) and with heatplots, cladograms, and other methods of data representation
    • Familiarity with phylogenetic reconstruction methods and programs
    • Ability to interact and communicate effectively with experimentalists in a team-oriented work environment
    • Ability to provide leadership, to train, or to mentor colleagues when needed
    • This position is subject to obtaining a Public Trust Clearance.

    HOW TO APPLY

    Please visit our website http://www.leidos.com/careers and search by requisition number 611360.

    POLICY

    Leidos is an Equal Opportunity Employer M/F/D/V.

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