RESPONSIBILITIES

• Accountable for the delivery of new molecular entities from DP3 to DP4.5 for Cardiovascular medicine
• Responsible for the definition of the clinical plan and for the design and implementation of the early clinical studies and of exploratory clinical research required to inform both discovery and development
• Works closely with Cardiovascular Discovery to identify novel targets, define the medical need and clinical relevance of that target in the context of the disease, and together with the discovery and biomarker leads to define the biology and biomarker package required at FIH
• Responsible for ensuring integration of TR&D activities across early development and integration of those activities into the clinical plan
• Accountable for assessing the resource needs required to deliver on the ECTR goals
• Critically evaluates licensing opportunities both molecular and technology, across the value chain in close partnership with business development
• Functions as co-chair for the Development Forum and is accountable for the definition of the clinical strategy for new molecules ensuring alignment with GCR and commercial and regulatory compliance
• Member of the ECTR SLT and contributes to the leadership and governance of the department ensuring scientific excellence and driving innovation
• Provides expert scientific and technical expertise to the Research Operating Committee Managing Multiple Stakeholders
• Ability to work effectively in a matrix environment that includes interactions with multiple stakeholder groups, including Research, Technical Operations, Clinical Development and the Commercial organization to ensure assets are developed in such a way as to have optimal market penetration at launch and throughout product lifecycle
• Organizational Leadership: Ability to execute on key organizational initiatives and provide a strategic view to the structure and design of the ECTR organization. Builds an organization that is focused on scientific excellence and operates with the utmost integrity at all times

REQUIREMENTS

• MD and or MD/PhD
• Extensive pharmaceutical, biotech firm and or relevant academic experience, including demonstrated strong investigative medicine skills and experience
• Track record of productive scientific management experience is required.
• Recognized expert in investigative medicine who can recruit and retain highly talented clinical researchers
• Experience in directing diverse investigative medicine studies/projects as investigator and as study director
• Experience in applying experimental medicine principles towards early drug development
• An expert recognized by the medical community and key investigators for their opinion/input on indications, protocol design and interpretation of findings
• Experience successfully guiding the development of compounds from discovery through early development

LOCALE

HOW TO APPLY