BACKGROUND:
Two specialists are sought in the area of Bioinformatics to specialize in computational systems facilitate high-throughput next generation sequencing and microarray analysis in the Center for Research Informatics, Research Resources Center (RRC), University of Illinois-Chicago in Chicago, Illinois USA. This position will interact with a multidisciplinary team consisting of geneticists, genomic & molecular biologists, and biomolecular specialists to render final analysis of data coming from various platforms. Identify mutations and other genomic features in a background of normal (wild-type) genes. Will also work on pathway analysis and other `omics data integration.

RESPONSIBILITIES:

• Maintain and operate commercial and open-source sequence database searching software tools for biomolecular identification technologies for RRC Research Informatics Core.
• Set up automated systems for processing of very large volumes of primary and derived data, data mining, statistical analysis, and reporting of results.
• Construct pipelines and workflows for sequence analysis and build custom algorithms and tools for specific problems.
• Work closely with the core laboratories and experimental biologists in analyzing data and collaborate with software engineers to generate robust and stable versions of software.
• Apply existing bioinformatics, and computational tools to projects and experiments.
• Consult with other scientists on study design, identifying elements from their data and suggest alternative approaches.
• Build, test and deploy pipelines and software workflows to deal with analyses.
• Employ high performance computing to solve parallelizable compute problems.
• Provide support and maintenance for existing applications; participate in production support, installation, testing and setup.
• Develop new software methodologies and computational tools as needed by research projects.
• Train students, post-docs and faculty in the use of software tools.
• Translate high-level specifications into business cases, object models and ultimately into designs and implementation.
• Design applications and software methodologies to meet scientific and technical requirements.
• Generate reports and briefs of sequencing analysis and experiments for the Research Resources Center's Research Informatics Core.
• Publish peer-reviewed scientific articles, and work with faculty and the Core Director to write federal grant proposals.
• Perform other related duties and participate in special projects as assigned.

REQUIREMENTS:

• Bachelor's degree in a biological sciences or related field required. Master's degree in biological sciences or informatics preferred, or equivalent 2 years specific experience in DNA sequence/microarray informatics required.
• BS or M. Sc. or equivalent in a computer science or mathematical discipline such as statistics preferred.
• Demonstrated understanding of sequence analysis methods required.
• Familiarity with the Linux &/or Unix computing environments required and previous experience implementing processes in a grid environment strongly desired.
• Experience with short-read DNA sequencing, gene expression, copy number variation, and other genetic anomalies desired.
• Experience in genome assemblies and consensus sequences desired.
• Proficiency in Perl, Python or other programming or scripting language required.
• Experience with SQL query language required.
• Experience developing with tools such as MATLAB and R or other scriptable statistical packages required.
• Experience with bioinformatics software such as BLAST, CLUSTALW, GMOD, ENSMBL, UCSC Genome Browser, EMBOSS, Galaxy, GenePattern.
• Working understanding of information systems and the ability to communicate effectively with IS professionals.
• Knowledge of commercial and publicly available bioinformatics tools and data sets.
• Experience in handling of diverse bioinformatics needs of scientists.
• Successfully demonstrated communication, writing and organization skills.
• The ability to relate biological processes to mathematical models that can be solved computationally.

LOCALE:
Chicago, IL

HOW TO APPLY:
Applicants should submit the following: cover letter highlighting key qualifications; current curriculum vitae with complete bibliography; names and addresses of three references. For fullest consideration, applications should be received by August 6, 2015. All materials should be uploaded to https://jobs.uic.edu/job-board/job-details?jobID=51758

DEADLINE:
August 6, 2015

POLICY:
The University of Illinois at Chicago is an Equal Opportunity, Affirmative Action employer. Minorities, women, veterans and individuals with disabilities are encouraged to apply.