BACKGROUND

Janssen Research and Development, L.L.C., a member of Johnson and Johnson's Family of Companies, is recruiting for a Postdoctoral Fellow, Computational Biology with an emphasis on Type 2 Diabetes in Springhouse, PA.

Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit http://www.janssenrnd.com for more information.

Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.

RESPONSIBILITIES

Selected postdoctoral candidates will join a dynamic cardiovascular and metabolic drug discovery and development organization that advances therapeutics to treat Type 2 diabetes. Candidates will have the opportunity to collaborate across the discovery and translational research departments at Janssen, as well as with prominent academic labs and recognized experts studying diabetes, the gut microbiome, alterations in circulating biomarkers and gene expression, and novel technologies in metabolism.

The area of focus for this position will be the identification and characterization of novel therapeutic targets and pathways linked to intestinal metabolism and mechanistic activation signatures in diabetes progression.

Candidates will be performing bioinformatics and statistical analysis, visualization and data interpretation of public and proprietary data for the Diabetes Disease Area Stronghold. Candidates will use statistical and machine learning methods to identify genomic and metabolomic related signatures associated with metabolic activity from high dimensional biological data. Candidates will integrate data from external (e.g. NCBI ENtrez, NCBI GEO, UCSC Genome Browser, TCGA/caBIG, GeneGO, Ingenuity) and internal sources in analyses. Candidates will work independently as part of a matrix organization. Candidates will communicate Bioinformatics results to computational biologists, bench scientists, clinicians and management in an appropriate biological context. Candidates must have an excellent publication record and strong written and verbal communication skills.

Please visit http://www.jnjpharmarnd.com for more information.

REQUIREMENTS

Candidates must have a PhD in Computational Biology or Bioinformatics. A candidate having strong BioConductor programming skills and working experience in a Unix/Linux environment is preferred. Experience in Diabetes and/or obesity is desired. Candidates with experience in high dimensional data integration, gene expression analysis, next generation sequencing analysis, metabolomic or metagenomic analysis, and biological network inference is preferred. Candidates with statistical analysis experience and a working knowledge of regression analysis, multivariate data analysis and linear/nonlinear mixed effects modeling is required. Scripting language experience (e.g. Perl or Python) is preferred. Other high level programming (e.g. Java, C++, etc.) and database (e.g. MySQL, PostgreSQL, Oracle) experience is preferred.

LOCALE

This position is located in Spring House, PA.

HOW TO APPLY

Apply here: http://www.Click2Apply.net/fm2z8j7k3v

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