[Next-Generation Sequencing Book]
  • [Photo] St. Jude Children's Research Hos • October 30, 2015

    BACKGROUND

    St. Jude Children's Research Hospital is a world-renowned institution that is recognized as one of the best places to work in the nation. As a premier center for research and treatment of childhood catastrophic diseases, we employ a diverse team of scientific and healthcare professionals dedicated to the promise of hope. Children from all 50 states and from around the world have come through the doors of St. Jude for treatment, and thousands more have benefited from our research.

    RESPONSIBILITIES

    Job Summary:
    St. Jude Children's Research Hospital's Computational Biology Department is looking for a highly motivated bioinformatics research scientist as the key analyst to integrate epigenetic, genomic and transcriptome data in the analysis of pediatric cancer. The Department has a well-established track record in leading bioinformatics analysis for high-profile genomic and translational research projects such as the St. Jude/Washington University Pediatric Cancer Genome Project which has resulted in multiple, high impact publications in the journals of New England Journal of Medicine, Nature, Nature Genetics, Nature Methods, JAMA and Cancer Cell. Computational Biology provides a highly collaborative teamwork environment, access to state-of-art computation infrastructure and visualization tools, highly automated analytical pipeline, and mentorship from senior scientists with deep experience in data analysis, data management and delivery of high-quality results for highly competitive projects. The bioinformatics research scientist will work on integrative analysis of whole-genome, whole exome and transcriptoming sequencing data with epigenetic data including ChIP-sez and ATAC-seq, and possibly incorporating DNase-seq, 4C-seq, ChIA-PET, and other methods to understand the role of epigenetic regulation in childhood cancer. This may include development of novel computational methods to facilitate clinical decision making, immunotherapy and pharmacogenomics. Candidates with deep understanding of cancer genomics, genetics or epigenetics, strong problem solving skills, attention to detail, critical thinking, and expertise in next-generation sequencing data analysis are highly encouraged to apply for this position.

    REQUIREMENTS

    Education/Experience Requirements:
    • Ph.D. in Molecular Biology, Biochemistry, Computer Science, Statistics, Mathematics, Bioinformatics or related field required.
    • Ph.D. which must include research related to bioinformatics (such as analysis of sequence data, microarrays, SNPs, image data, proteomics data, or biological pathways; development of algorithms, statistical methods, or scientific software).
    OR
    • If Ph.D. with no bioinformatics research, then two (2) years of pre-or postdoctoral experience in Computational Biology or Bioinformatics research is required.
    • Experience with programming languages such as Perl, C, or Java required.

    PREFERENCES

    Preferred skills: Experience with Python and knowledge on statistical analysis package such as R and Matlab is highly desired. Experience in epigenetics analysis such as ChIP-seq, ATAC-seq, DNase-seq, 4C-seq, ChIA-PET, WGBS is preferred. Knowledge about neurobiology is also a plus.

    LOCALE

    Memphis, TN

    HOW TO APPLY

    To apply online, visit: https://jobs.stjude.org/css_external/CSSPage_Referred.ASP?Req=34818&s_cid=3-1-391-5-25968

    Department: Computational Biology
    Job Number: 34818

    POLICY

    St. Jude Children's Research Hospital is an Equal Opportunity Employer. St. Jude does not discriminate on the basis of race, national origin, sex, genetic information, age, religion, disability, sexual orientation, gender identity, transgender status, veteran's status or disabled veteran's status with respect to employment opportunities.  All qualified applicants will be considered for employment.  St. Jude engages in affirmative action to increase employment opportunities for minorities, women, veterans and individuals with disabilities.

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