DESCRIPTION:
About The Hospital For Sick Children:
Dedicated exclusively to children and their families, The Hospital for Sick Children (SickKids) is one of the largest and most respected paediatric healthcare centres in the world. As innovators in child health, we lead and partner to improve the health of children through the integration of healthcare, leading-edge research and education. Our reputation would not have been built – nor could it be maintained – without the skills, knowledge and experience of the extraordinary people who come to work here every day. SickKids is committed to ongoing learning and development, and features a caring and supportive work environment that combines exceptionally high standards of practice.

When you join SickKids, you become part of our community. We share a commitment and determination to fulfill our vision of Healthier Children. A Better World.

Don't miss out on the opportunity to work alongside the world's best in paediatric healthcare.

Bioinformatician:
Are you a bioinformatician interested in using your expertise in gathering and analyzing information to help improve the lives of children? Are you interested in working alongside world experts and being a part of an esteemed program dedicated to finding new therapies for heart failure? Would you enjoy being an integral member of an organization dedicated to providing excellence and innovation in patient care, research, and education?

The Ted Rogers Centre for Heart Research (TRCHR) Precision Cardiac Medicine Program at SickKids is seeking a motivated Senior Bioinformatician who is experienced in dealing with very large volumes of genomic data with strong computer programming skills. This work will be performed in our research laboratory which is dedicated to identifying the genetic causes of heart failure, cardiomyopathies and congenital heart disease.

The Ted Rogers Centre for Heart Research is a newly formed centre in Toronto, Canada, created from one of the largest monetary gifts ever made by the Rogers family of $130 million to bring together three world class institutes: Hospital for Sick Children, University Health Network, and University of Toronto, with the goal of finding new therapies for heart failure. As part of this Centre, the SickKids Program in Precision Medicine will harness the power of genomics and stem cells to develop personalized medicine strategies for patients with heart failure. The program will sequence the genomes of several thousand individuals with heart failure. Genetically characterized patient iPSCs will be differentiated into cardiovascular lineages to identify the molecular signature of childhood onset heart failure and to perform high throughput drug screens to identify new drug therapies.

Here's What You'll Get To Do:

• Leverage appropriate software, tools, and applications to solve bioinformatics problems.
• Write scripts/programs for bioinformatic tasks (e.g., sequence annotation and variant calling).
• Access and analyze large repositories of data through scripting procedures. Query and maintain database for genomic information
• Analyze biological datasets like whole genomes, whole exomes, RNAseq, miRNA screens, DNA microarrays and biomarker data
• Leverage high performance computing service by writing scripts for large jobs.
• Document and manage tasks employing good programming practices in commenting code, minimizing errors, and maximize efficiency (e.g., reusability of code).
• Responsible for executing multiple bioinformatics priorities for the lab or core facility.
• Work independently to meet deadlines.
• Provide input and guidance to trainees, lab staff, or scientists to advance research or project objectives.
• Communicate results and findings of analyses to investigators.

Here's What You'll Need:

• Minimum of Bachelors level education in Computer Science, Bioinformatics or equivalent experience (Masters preferred)
• Experience with large genomic (genome-wide array and/or next generation sequencing) datasets and relevant databases (e.g., Gene Ontology, UCSC Genome Bioinformatics)
• Familiarity with specific laboratory or core facility processes, guidelines, and tools (e.g. sequence alignment, variant annotation)
• Experience with computer operating systems (e.g., UNIX, Windows), programming and scripting (e.g., R, Python, Perl), data storage, management and analysis (SQL, SAS)
• Experience with data visualization and presentation tools
• Excellent communication skills and thrive in a collaborative team
• Candidates who possess knowledge and education in a biology-related field as well as computing will be preferred.
• Knowledge and familiarity with genetics and cardiovascular biology is an asset.
• Minimum of one year experience in an academic or industry setting where the individual has received training in and/or been able to apply knowledge working with data sets
• Applicants with less experience may be considered for a junior bioinformatician position.

TERMS:
Employment Type: Permanent, Full-Time

HOW TO APPLY:
Click here to apply http://tinyurl.com/BioinformaticianPosting

For additional information, please visit us at http://www.sickkids.ca

POLICY:
Our Commitment to Diversity:
SickKids is strongly committed to diversity within its community and welcomes applications from visible minority group members, women, Aboriginal persons, persons with disabilities, members of sexual minority groups and others who may contribute to diversity within our organization.

SickKids is also committed to providing services in both official languages and our preference is to hire employees who are fluent in both English and French whenever possible.

Thank you for your interest in joining SickKids. Only those applicants selected for an interview will be contacted. In accordance with our Hospital policy, employment at SickKids is conditional upon the Hospital's receipt of all necessary documentation.