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RESPONSIBILITIES

Highly motivated Software Developer/Bioinformatician to help analyse and visualise data from large-scale (Big Data) Cancer Sequencing Studies.

A maternity cover Senior Bioinformatician position has become available within the Cancer Genome Project (CGP) at the Wellcome Trust Sanger Institute (WTSI). The role involves working closely with scientific and IT staff on the project to ensure the efficient analysis of data generated by the project. Specifically, this will include developing IT systems to track the data, to accurately call mutations from cancer samples, analyse the patterns of mutations across all samples and across other cancer types.

The position would suit a Bioinformatician who enjoys applying their skills to analysing large biological data sets (Big Data) and finding novel ways to analyse and display such data. We are looking for an individual who enjoys working in multi-disciplinary team environment to help solve complex biological problems relating to cancer genetics.

REQUIREMENTS

Essential Skills:

Good degree in Bioinformatics, Scientific Discipline or Computer Science
Experience of one or more of the following Perl, Java, R, Python, C/C++
Database skills using ORACLE or MySQL
Development experience in a UNIX/LINUX environment
Ability to work independently and organise own workload
Enjoy working as part of a team

PREFERENCES

Ideal Skills:

Experience of workflow management IT systems
Experience working, developing and compiling software tools in a UNIX/LINUX

environment.

Experience of handling Next Generation sequencing data
LSF or Open Grid scheduling software
Background or interest in cancer genetics
Web development

ABOUT US

The Wellcome Trust Sanger Institute operates at the forefront of genomics, sequencing and analyses targeting a wide range of genomes from single cell pathogens to higher vertebrates, with an emphasis on genomes relevant to human medicine and welfare. The Cancer Genome Project at the Institute has led the way in the systematic analysis of cancer genomes by using the human genome sequence and high throughput mutation detection techniques to identify somatically acquired sequence variants/mutations and hence identify genes critical in the development of human cancers (http://www.sanger.ac.uk/genetics/CGP/).

The IT group has developed a suite of algorithms to analyse genetic variation in cancer genome data. This includes software to detect tumour genetic variation (e.g. single-base substitutions, structural rearrangements, copy number changes) and the ability to annotate the resulting variants and mine the data for patterns and signatures.

The Sanger Institute is a charitably funded research centre that applies the power of genomics to uncover the basis of genetic and infectious disease. We conduct science at a scale and speed that sets our research apart. Our passion is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.

The Institute is located near Cambridge on the stunning Wellcome Trust Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), the Centre for Therapeutic Target Validation, the sequencing centre for Genomics England's 100,000 Genomes Project and will soon host a Biodata Innovation Centre. It is an excellent environment in which to work and collaborate with researchers on campus and around the world and benefit from cross-fertilisation of ideas.

To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops. In addition the Campus is home to the Wellcome Trust Advanced Course and Scientific Conferences programme and the Wellcome Trust Conference Centre.

TERMS

Maternity cover of up to 12 months

COMPENSATION

GBP 31033 to GBP 39142pa dependent on experience

Our Benefits include: Defined Benefit Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Nursery and 25 days Annual Leave plus Bank Holidays. We also have a gym, two cafes, a nursery, dining facilities, and a free campus Bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

Please state your current salary in the covering letter.

HOW TO APPLY

Application link: https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=256702

DEADLINE

Closing date: 14th April 2016

Discussion forums: Opportunity: Senior Bioinformatician (Maternity Leave Cover) -- Cancer Genome Project @ Wellcome Trust Sanger Institute -- Hinxton/Cambridge, UK

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