BACKGROUND

The Rady Children's Institute for Genomic Medicine brings together world-class scientists and clinicians into a shared research infrastructure, one that will enable them to accelerate the translation and implementation of research discoveries for prevention, diagnosis, treatment, and ultimately cures for childhood diseases. Under the direction of world-renowned researcher Stephen Kingsmore, M.D., D.Sc., the Institute seeks to translate research findings into new clinical tests and treatments to improve patient outcomes, enhance the knowledge in this field among current and future healthcare providers and generate and share data and discoveries with other researchers.

We have an immediate opening a Bioinformaticist.

RESPONSIBILITIES

We are looking for superstar computational-biologists/bioinformaticists who have a demonstrated experience in a large-scale production setting to deploy, maintain and evolve the bioinformatics framework for a high-throughput; ultra-rapid turnaround time whole-genome sequencing based clinical setting. You will have the opportunity to be a part of a team that'll build the infrastructure ground up using the latest and greatest of the technologies in infrastructure, data storage and analytics, with a strong focus on automation and integration. The environment is highly cross-functional, with a rich medical research heritage and multitude of collaborations with the biotech industry, academic institutions and federal programs. The end deliverable from your work will tangibly influence the quality of life of the children being seen at the hospital making your work experience exciting, challenging, rewarding and meaningful. And to top it all, you'll be located in one the finest cities in the country, with a wonderful year-round weather and a multitude of outdoor activity options.

Depending on the level of relevant experience, your candidature will be considered for the (junior/senior) bioinformaticist positions.

REQUIREMENTS

Minimum Qualifications:
Bachelor's degree in Computer Science, Information Systems, Bioinformatics or Life Sciences, including fields, i.e., Biology, Molecular Biology, Genetics.
Two to five years' experience analyzing next-gen sequencing data (Illumina whole genomes or exomes): BCL to annotated variants
Two to five years' experience developing and maintaining pipelines for 24x7 automated bioinformatics analyses
Two to five years' experience integrating pipeline with the LIMS
Two to five years' experience working with and understanding of open source NGS tools like bwa, samtools, vcftools, picard, GATK, Freebayes, ANNOVAR, VEP, etc.
Two to five years' experience incorporating dbGaP, 1000 genomes, ExAC, Clinvar, OMIM, etc
Two to five years' experience with unix/linux operating system
Two to five years' experience software development using any of Ruby, Python, Perl, Bash
Two to five years' experience working with SVN, git
Two to five years' experience working with HPC scheduling systems such as Moab, TORQUE, LSF, OpenGrid Engine, etc.

PREFERENCES

Preferred Qualifications:
Demonstrated experience working in CNV and SV calling
Demonstrated experience in phenotype-genotype integration frameworks
Demonstrated experience working with cloud-based development or analysis
Demonstrated experience working in a CAP/CLIA environment
Demonstrated experience performing benchmarking of bioinformatics tools
Demonstrated experience developing and working with Docker and AWS images
Demonstrated experience in database development using MySQL, or any NoSQL flavors
Demonstrated experience in setting up and computing on a hadoop cluster
Demonstrated experience programming using C or Java

HOW TO APPLY

For more information and to apply: http://jobs.rchsd.org/bioinformaticist-full-time-benefits-eligible/job/5992307

POLICY

EEO/AA/Minorities/Females/Disabled/Veterans