[Next-Generation Sequencing Book]
  • [Photo] Grainne Burns • April 27, 2016

    BACKGROUND

    Zymeworks is a fast-growing biotechnology company dedicated to the research, development and commercialization of best-in-class therapeutic bispecific antibodies and antibody drug conjugates for treatment of cancer and autoimmune diseases. Zymeworks is proud to have active collaborations with Merck & Co., Inc., Eli Lilly and Co., GSK and Celgene Corporation, and is committed to making a meaningful difference in the lives of patients.

    RESPONSIBILITIES

    Zymeworks is seeking a Scientist, who will be responsible for developing statistical and bioinformatics tools for advancing our in-house technology platform for antibody engineering and therapeutic development. The position reports to the Technology Integration Team Lead.

    Roles and Responsibilities:
    • Develop and implement bioinformatics methods for application in protein engineering, optimization and antibody discovery.
    • Develop and implement robust statistical and data mining techniques for the analysis of experimental and in silico data.
    • Work with the Protein engineering and Therapeutics R&D teams to gather requirements and specifications for bioinformatics developments.
    • Assist in data driven statistical analysis and validation of Protein Engineering and Preclinical experiments.
    • Collaborate with the software development group for the implementation of user-friendly bioinformatics tools.
    • Conduct analysis of genomic data from external data sources and literature supporting the discovery and characterization of targets and biomarkers.
    • Assist with special projects and other duties as assigned.
    • Participate in the development of rigorous documentation and standard operating procedures.

    REQUIREMENTS

    Required Qualifications and Experience:
    • MSc or PhD in Bioinformatics, Mathematics, Computer Science or related field
    • Strong skills in protein informatics and protein science, including protein sequence analysis and genomic analysis
    • Strong background in statistical analysis with experience in R, SPSS or other statistical packages
    • Experienced in implementing and validating protein informatics methods
    • Experienced in manipulation and analysis of high-throughput sequencing data
    • Experienced in analyzing biological and genomic databases such as TCGA, ICGC etc.
    • Experienced in the application of machine learning algorithms for data analysis
    • Proficient in Python or any other programming language
    • Demonstrated ability to effectively communicate in spoken and written English
    Additional Qualifications and Experience:
    • Knowledge of molecular simulations
    • Experienced in biostatistics and clinical data analysis

    ABOUT US

    Why Work for Us?

    Zymeworks' employees are passionate, engaged and extremely motivated to succeed. Our environment is progressive, collaborative, focused and pragmatic.

    Compensation is on par with industry standards and commensurate with experience and includes an extended benefits plan and participation in the employee stock-option plan.

    To learn more about Zymeworks Inc. and our current openings, please visit our website at http://www.zymeworks.com

    HOW TO APPLY

    If you are interested in applying for this position, please do so through our online jobs board at https://zymeworks.mytribehr.com/careers/view/44. Although we appreciate all applications, due to the high volume of responses only those selected for interviews will be contacted.

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