Bioinformatics.org
|
|
Research
|
Online databases
Online analysis tools
Online education tools
|
Development
|
|
Forums
|
News & Commentary
Jobs Forum (Career Center)
|
|
News & Commentary - Message forums
|
|
|
|
Resources: Cello: Genetic circuit design automation
Submitted by Prashanth N Suravajhala; posted on Thursday, August 25, 2016
|
EXCERPT
The Cello input is a high-level logic specification written in Verilog, a hardware description language. The code is parsed to generate a truth table, and logic synthesis produces a circuit diagram with the genetically available gate types to implement the truth table. The gates in the circuit are assigned using experimentally characterized genetic gates. In assignment, a predicted circuit score guides a breadth-first search, or a Monte Carlo simulated annealing search. The assignment with the highest score is chosen, and this assignment can be physically implemented in a combinatorial number of different genetic layouts. The Eugene language is used for rule-based constrained combinatorial design of one or more final DNA sequence(s) for the designed circuit.
|
|
Expanded view | Monitor forum | Save place
Start a new thread:
You have to be to post a reply.
|
|