[I, Librarian]
  • [Photo] Ilya Oblomov • October 20, 2016

    BACKGROUND

    CEA-Genoscope, a dynamic non-profit scientific research organization dedicated to sequence-based science and the advancement of environmental genomics, has two exciting opportunities available for talented and motivated computational biologists or computer programmers.

    The successful candidates will join efforts to extend the range of "assembly-free" and/or "pre-assembly" analyses of metagenomes to unprecedented scales, including by leveraging the power of a massive-memory computer endowed with 30 terabytes of RAM. This dedicated hardware architecture will enable in-memory analyses of terabytes of data (e.g. factorizations of very large matrices), empowering the joint mining of thousands of metagenomic samples, for example to reconstruct across samples the genomes of low abundance bacterial strains.

    The envisioned approach will fully exploit the coverage covariation signal that is embedded in the larger cohorts that are increasingly becoming available for investigating the biomedical impacts of variation in the human microbiome, and will contribute to move the field of metagenomics towards a more strain-resolved and more genome-centric endeavor.

    The successful candidates will be working with the latest technology in a freethinking and dynamic environment. We are looking for individuals who have good communication skills and enjoy working in a multi-disciplinary environment. The position is based at the Genoscope department of CEA's Genomics Institute, and is available immediately.

    REQUIREMENTS

    The candidates should have strong skills in software engineering and have first-hand experience of processing very large datasets in a scientific or commercial domain. We are a multi-disciplinary team, and the successful applicant will work collaboratively with a range of other specialists, therefore teamwork and a collaborative ethos are required.

    Essential Skills:
    • Postgraduate qualification in a data-driven field, with educational emphasis in machine learning, statistics or data science
    • Proven software engineering skills with proficiency in Java or C++
    • Experience of processing large datasets on parallel computing infrastructures
    • Strong analytical and problem solving skills
    • Ability to track and incorporate innovative tools and methods in the public domain
    • Ability to independently carry out creative research with tenacity
    • Strong communication skills, both oral and written

    TERMS

    The two assignments are for a two-year period each.

    LOCALE

    Rapid technological advances in genomics have transformed modern biology. From its inception, Genoscope has been at the forefront of large-scale sequence-based science. Today, our institute performs biological and bioengineering research with applications in environment, healthcare and alternative energy. The Genoscope department of CEA's Genomics Institute harbors a multidisciplinary team of approximately 120 staff, postdocs and technologists with expertise in molecular biology, bioinformatics, microbiology and organic chemistry.

    A major basic research activity in the department aims at developing a systems-level understanding of microbiomes relevant to environment and/or human health. Applied research activities are focused on enzyme and microbial engineering for bioremediation, biological detection and biofuels development.

    The Institute is located near Paris (France) on the stunning Evry Genopole Campus, which is part of the emerging Paris-Saclay federal research university. This growing and dynamic site is an excellent environment in which to work and collaborate with researchers on campus and around the world, and benefit from cross-fertilization of ideas.

    HOW TO APPLY

    Review of applications will begin immediately. Interested individuals should send a CV, cover-letter and the names of three references to bruls[at]genoscope.cns.fr with a subject line "adamme-2017 positions".

Discussion forums: Opportunity: Two Positions for Bioinformatics Engineers / Software Developers in Computational Metagenomics @ CEA-Genoscope -- Paris, France

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