BACKGROUND:
OHSU is ranked as one of the nation's top biomedical institutions in patient care, research, and education, with an annual operating budget of over $2.3 billion, over $340 million in annual grant funding, over 4,000 students and trainees, and nearly 1 million patient visits per year. Multiple departments rank among the top 5 in annual grant funding, including neuroscience, microbiology, ophthalmology, otolaryngology, and emergency medicine. OHSU is one of the nation's fastest growing biomedical institutions, bolstered by long-term resource commitments, such as the $1 billion Phil and Penny Knight "challenge" to support research in OHSU's Knight Cancer Institute, led by Dr. Brian Druker, who pioneered the concept of gene targeted therapy by demonstrating the efficacy of the revolutionary cancer drug Gleevec in chronic myelogenous leukemia.

OHSU provides substantial resources to enable data intensive science, including a world-class exascale super computing cluster, close interactions and resource commitments by leading technology companies such as Intel, tight integration with clinical and basic research programs across campus, graduate training programs in quantitative biosciences, biostatistics, biomedical informatics, bioinformatics and computational biology, and substantial long-term resource commitments, including the $1 billion Phil and Penny Knight "challenge" to support cancer research, with a significant focus on computation.

RESPONSIBILITIES:
1. Develop custom analytics and data management applications to facilitate one or more of the following: large-scale genomic data analysis; machine learning methods to infer genotype-to-phenotype predictive models; analysis of quantitative imaging data.
2. Work with the platform development team to implement scalable cloud-enabled workflows to disseminate analytical advances to the research community.
3. Establish and maintain standards for structured software & systems engineering, including requirements, design, code, test, quality, configuration & release management and project management.
4. Provide documentation and user support allowing computational researchers across campus to access and re-use analysis tools.
5. Develop tools to integrate commonly used open source bioinformatics software applications.
6. Participate in leading international efforts aimed at establishing best practices and standards for genomic data representation and analysis.

REQUIREMENTS:

• Bachelor's degree with major courses in field of research. Additional experience in lieu of degree may be considered.
• Experience in one of the following:
  
  • Analyzing next-generation DNA or RNA sequencing data
  • Advanced machine learning or statistical techniques, such as probabilistic graphical models, Bayesian inference, and optimization methods
  • Image processing algorithms and biomedical image analysis workflows
• Experience using structured engineering methods for specifying, designing, and implementing systems
• Experience with architecture and tools for managing "omics" or imaging data
• Advanced skills in a high level programming language, preferably Python, R, or Java
• Ability to prioritize multiple tasks at one time
• Excellent communication, analytical and organizational skills, both written and verbal
• Ability to work independently and as part of a team while being collaborative in resolving problems
• A desire to change the world and contribute to the elimination of human disease

PREFERENCES:

• Masters or doctorate degree in field of research
• At least 3 years' experience with distributed file systems, such as Lustre, and working with "big data"
• High performance computing experience in a Unix/Linux environment
• For image analysis, familiarity with commonly used tools such as Slicer or CellProfiler
• Experience in a professional, team-oriented software development environment
• A passion for open-access innovation

LOCALE:
Portland, OR

HOW TO APPLY:
Go to "Find a Job" at the OHSU Jobs site (https://ais.ohsu.edu/OA_HTML/IrcVisitor.jsp) and search under job posting ID: IRC46014

DEADLINE:
Open till filled

POLICY:
Inclusion, Collaboration and Teamwork:
Every person matters. We benefit from the rich variety of ideas, skills and perspectives that emerge when we work together. Our collaboration fuels innovation, better solutions to complex problems, and a sense of community. Cultivating a climate of inclusion and respect enables us to partner with those who can help OHSU achieve its vision.

See the specific behaviors expected of an individual in this role on the attached document.

Organizational Perspective:
We are all connected. Whether our role is caring for patients, inspiring students, advancing scientific knowledge, or supporting those endeavors, each person's work impacts another's. When we understand how our actions and decisions affect the whole, we can better align the needs of our workgroup with the best interests of OHSU. We have a common purpose that guides what we do and why.

See the specific behaviors expected of an individual in this role on the attached document.

Performance Results:
We work hard to make great things happen. We hold ourselves and our colleagues to high standards of performance that are focused on results. We pursue excellence by giving and receiving feedback openly and directly. We continually seek to improve ourselves and our work by setting goals, measuring outcomes and developing our knowledge and skills. We exceed expectations in pursuit of our vision.

Personal Effectiveness:
We are strong in character. As individuals, we value integrity and inspire trust. We meet obstacles with calm resolve, and can adapt quickly to change. We continue to move forward, even when the way is unclear. Each of us aspires to be our best self, accountable for the work we do and dedicated to the purpose of OHSU.